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VASCULAR GRAFTS

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https://www.readbyqxmd.com/read/29663585/perioperative-anticoagulation-practices-for-pediatric-liver-transplantation
#1
Stylianos Voulgarelis, Bernadette Vitola, Stacee M Lerret, Johnny C Hong, John P Scott
Despite continued advancements in perioperative care for pediatric liver transplant (LT), graft-threatening vascular occlusion events including hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) remain a source of significant morbidity and mortality. Perioperative anticoagulation is commonly used for the prevention of HAT and PVT, but evidence-based guidelines are lacking. The goals of this survey were to determine the frequency of use of an anticoagulation protocol and to describe variation in anticoagulation practices among pediatric LT centers...
April 16, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29661648/one-year-rat-study-of-ibta-induced-microbiotube-microvascular-grafts-with-an-ultra-small-diameter-of-0-6-mm
#2
Daizo Ishii, Jun-Ichiro Enmi, Ryosuke Iwai, Kaoru Kurisu, Eisuke Tatsumi, Yasuhide Nakayama
OBJECTIVE: The world's smallest calibre "microbiotube" vascular graft was recently developed, with an inner diameter of 0.6 mm. It was formed using in-body tissue architecture (iBTA) and has a high degree of patency and capacity for regeneration in the acute phase, 1 month after implantation. This consecutive study investigated the compatibility and stability of microbiotubes in the chronic phase of implantation for 12 months for potential application in microsurgery. METHODS: This was an in vivo experimental study...
April 13, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29661443/cyclosporine-versus-tacrolimus-which-calcineurin-inhibitor-has-influence-on-cytomegalovirus-infection-in-cardiac-transplantation
#3
Marina M K Bond, Marisa M K Bond, A Sehn, V H Dias, T L Said, C C Dos Santos, M A Finger, A M G Santos, J M R Neto
INTRODUCTION: Cytomegalovirus (CMV) infection is a relevant cause of morbidity and mortality in transplantation patients. Its major incidence is in the first year and viral replication is related to acute rejection, survival reduction, and graft vascular disease. OBJECTIVE: This study aims to evaluate retrospectively whether a high dose of calcineurin inhibitors correlates with CMV-positive polymerase chain reaction (PCR), need for treatment, and death in cardiac transplantation patients...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29660052/side-to-side-and-end-to-side-double-anastomosis-using-the-parietal-branch-of-the-superficial-temporal-artery-a-novel-technique-for-extracranial-to-intracranial-bypass-surgery-3-dimensional-operative-video
#4
Gregory D Arnone, Ziad A Hage, Fady T Charbel
In this 3-dimensional video, we perform a side-to-side and end-to-side double anastomosis using the parietal-branch of the superficial temporal artery (STA) to provide flow augmentation in a symptomatic 59-yr-old male with bilateral internal carotid artery occlusion at the origin, and left M1 segment occlusion. The patient suffered multiple left hemispheric strokes despite maximal medical therapy and was found to have poor hemodynamic reserve in the left hemisphere during evaluation with regional and global blood oxygenation level-dependent functional magnetic resonance imaging with CO2-challenge as well as quantitative magnetic resonance angiography and noninvasive optimal vessel analysis pre- and post-acetazolamide challenge...
April 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29658944/an-in-vivo-model-of-functional-and-vascularized-human-brain-organoids
#5
Abed AlFatah Mansour, J Tiago Gonçalves, Cooper W Bloyd, Hao Li, Sarah Fernandes, Daphne Quang, Stephen Johnston, Sarah L Parylak, Xin Jin, Fred H Gage
Differentiation of human pluripotent stem cells to small brain-like structures known as brain organoids offers an unprecedented opportunity to model human brain development and disease. To provide a vascularized and functional in vivo model of brain organoids, we established a method for transplanting human brain organoids into the adult mouse brain. Organoid grafts showed progressive neuronal differentiation and maturation, gliogenesis, integration of microglia, and growth of axons to multiple regions of the host brain...
April 16, 2018: Nature Biotechnology
https://www.readbyqxmd.com/read/29658528/gait-changes-in-patients-after-reconstruction-of-facial-bones-with-fibula-and-iliac-crest-free-vascularized-flaps
#6
Małgorzata Syczewska, Romuald Krajewski, Monika Kirwil, Ewa Szczerbik, Małgorzata Kalinowska
PURPOSE: Patients with malignant tumours of the oral cavity require its surgical removal and reconstruction of the bone and soft tissues. The grafts are obtained either from leg (fibula) or pelvis (iliac crest). The removal of grafts from the locomotor apparatus can impair the gait. The aim of this study was to find out how the localization of donor site influences the gait pattern. METHODS: Results obtained for 30 patients were analyzed (16 fibula graft, 14 iliac crest graft)...
2018: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29657207/adoption-of-transposed-basilic-vein-as-access-for-hemodialysis
#7
Jacob A Akoh
The fistula first initiative has rekindled interest in transposition of basilic vein (TBV) in preference to arteriovenous grafts (AVG). TBV is considered to have advantages over AVG. The aim of this study was to analyze the outcome of TBVs in our center comparing them to a historically matched group of patients who had AVG. Thirty-two patients who underwent TBV as a vascular access procedure in Derriford Hospital between January 2010 and October 2014 were included in the study. The historical control group comprised 31 patients who had AVG inserted in the upper arm between January 1999 and December 2010...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29656899/long-term-outcome-of-patients-with-or-without-osseointegrated-implants-after-resection-of-mandibular-ameloblastoma-and-reconstruction-with-vascularized-bone-graft-functional-assessment-and-quality-of-life
#8
Marco Pappalardo, Chung-Kan Tsao, Man Lung Tsang, Jie Zheng, Yang-Ming Chang, Chi-Ying Tsai
BACKGROUND: The optimal management after the resection of mandibular ameloblastoma has been very challenging to surgeons. The aim of this study is to evaluate the functional, aesthetic, and quality of life outcomes of patients who had a segmental mandibular resection and immediate reconstruction with or without osseointegrated implants. METHOD: Patients' demographics, tumor characteristics, treatment, and complications were retrieved. Patients were divided into two groups: dental rehabilitated vs...
March 28, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29655988/tissue-engineering-still-facing-a-long-way-ahead
#9
REVIEW
Parichehr Hassanzadeh, Fatemeh Atyabi, Rassoul Dinarvand
Tissue engineering (TE) has provided promising perspectives to overcome the limited efficiency of the conventional treatment options or organ transplantation. Considerable advances in stem cell therapies and biomaterials science and development of delivery systems capable to mimic the production of growth factors may offer treatment breakthroughs in a variety of diseases. Meanwhile, proper vascularization, creation of the complex tissues, tissue quality, functional integration between the graft and host tissues, and the potential risks of chromosomal instability, mutations, tumorigenesis, or unexpected events have remained challenging...
April 12, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29653080/surgical-treatment-of-native-and-prosthetic-aortic-infection-with-xenopericardial-tube-grafts
#10
Maximilian Kreibich, Matthias Siepe, Julia Morlock, Friedhelm Beyersdorf, Stoyan Kondov, Johannes Scheumann, Fabian A Kari, Tim Berger, Holger Schröfel, Bartosz Rylski, Martin Czerny
BACKGROUND: To report our results of surgical treatment of native and prosthetic aortic infection with xenopericardial tube-grafts from the ascending aorta to beyond the bifurcation. METHODS: Within a 28-month period, 20 patients were treated with a bovine self-made pericardial tube graft to replace infected vascular grafts (after conventional surgical aortic replacement or endovascular stentgraft implantation) or to treat a contaminated surgical site. An integrated standardized therapeutic concept was applied in all patients consisting of complete removal of the infected prosthetic material, extensive debridement, and orthotopic vascular reconstruction with self-made tube grafts constructed from a bovine pericardial patch...
April 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29650408/normothermic-ex-vivo-preservation-with-the-portable-organ-care-system-lung-device-for-bilateral-lung-transplantation-inspire-a-randomised-open-label-non-inferiority-phase-3-study
#11
Gregor Warnecke, Dirk Van Raemdonck, Michael A Smith, Gilbert Massard, Jasleen Kukreja, Federico Rea, Gabriel Loor, Fabio De Robertis, Jayan Nagendran, Kumud K Dhital, Francisco Javier Moradiellos Díez, Christoph Knosalla, Christian A Bermudez, Steven Tsui, Kenneth McCurry, I-Wen Wang, Tobias Deuse, Guy Lesèche, Pascal Thomas, Igor Tudorache, Christian Kühn, Murat Avsar, Bettina Wiegmann, Wiebke Sommer, Arne Neyrinck, Marco Schiavon, Fiorella Calebrese, Nichola Santelmo, Anne Olland, Pierre-Emanuel Falcoz, Andre R Simon, Andres Varela, Joren C Madsen, Marshall Hertz, Axel Haverich, Abbas Ardehali
BACKGROUND: Severe primary graft dysfunction (PGD) of grade 3 (PGD3) is a common serious complication following lung transplantation. We aimed to assess physiological donor lung preservation using the Organ Care System (OCS) Lung device compared with cold static storage. METHODS: In this non-inferiority, randomised, controlled, open-label, phase 3 trial (INSPIRE) recipients were aged 18 years or older and were registered as standard criteria primary double lung transplant candidates...
April 9, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29650375/vascularized-distal-radius-bone-graft-for-treatment-of-ulnar-nonunion
#12
REVIEW
Ezequiel Ernesto Zaidenberg, Ezequiel Martinez, Carlos Rodolfo Zaidenberg
Various methods have been reported to treat forearm nonunions with good results. However, in the presence of infection, inadequate vascularity of surrounding tissues, or failed prior grafts, vascularized bone grafts are a valid alternative. We describe the surgical technique to obtain distal radius vascularized bone graft pedicled on the radial artery (RA) and its clinical application in 1 case of an ulnar nonunion. We studied the surgical technique in 12 freshly injected cadavers. In the distal forearm, the RA provides several periosteal branches to supply the distal radius metaphysis...
April 9, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29649585/effects-of-different-serotonin-receptor-subtype-antagonists-on-the-development-of-cardiac-allograft-vasculopathy-in-murine-aortic-allografts
#13
Annika Gocht, Jörg H W Distler, Bernd Spriewald, Martina Ramsperger-Gleixner, Michael Weyand, Stephan M Ensminger, Christian Heim
BACKGROUND: Cardiac allograft vasculopathy (CAV) is the main obstacle for long-term survival after heart transplantation. Alloimmune mediated chronic vascular rejection results in several mechanisms like platelet activation, immigration of inflammatory cells through the endothelial layer and proliferation and migration of smooth muscle cells (SMCs). Serotonin (5-HT) promotes these processes via activation of 5-HT2 receptors. We hypothesized that inhibiting 5-HT2 receptors ameliorates the development of CAV...
April 9, 2018: Transplant Immunology
https://www.readbyqxmd.com/read/29645355/the-european-experience-on-robot-assisted-kidney-transplantation-minimum-of-one-year-follow-up
#14
Angelo Territo, Lluis Gausa, Antonio Alcaraz, Mireia Musquera, Nicolas Doumerc, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Selcuk Sahin, Volkan Tuǧcu, Giuseppe Basile, Alberto Breda
OBJECTIVES: To evaluate functional results, graft survival, and late complications in patients who underwent robot-assisted kidney transplantation (RAKT), with a minimum follow-up of one year. In addition: to analyze the correlation between surgical data and functional results at a minimum 1-year follow-up and the correlation between renal function in the immediate postoperative period and after one year. MATERIALS AND METHODS: A common prospective recruitment database of RAKT was created by the European Robotic Urological Section (ERUS) RAKT working group, including eight different European centers...
April 12, 2018: BJU International
https://www.readbyqxmd.com/read/29644315/limb-salvage-and-reconstruction-following-a-zebra-attack
#15
Jacob T Carlson, James C Yuen, Matthew R Smeds
Animal bites are fairly rare events but can cause devastating traumatic injuries to the victim. In addition to the soft tissue, vascular, and orthopedic trauma inflicted by these occurrences, bite injuries also have the potential to introduce an inoculum of microbes, which may progress to an infection if not treated properly and expeditiously. We present the case of a healthy male who sustained multiple bite wounds from a domestic zebra to his left upper extremity. This attack caused severe damage, including devascularization of the arm at the brachial artery, disruption of the distal biceps and brachialis, stripping of the forearm nerves, and shearing of the overlying soft tissue...
June 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644103/morphometric-study-of-the-semitendinosus-muscle-and-its-neurovascular-pedicles-in-south-indian-cadavers
#16
Rajanigandha Vadgaonkar, Manoor Dass Prameela, Bukkambudhi Virupakshamurthy Murlimanju, Mamatha Tonse, Chettiar Ganesh Kumar, Amit Massand, Vandana Blossom, Latha Venkatraya Prabhu
The purpose of this study was to determine the length of the semitendinosus muscle belly and its tendon in South Indian population and to study the topography and diameter of its neurovascular pedicles. The study included 46 formalin fixed human cadaveric lower limbs. The length of the semitendinosus muscle belly and its tendon were measured. The neurovascular pedicles of the semitendinosus muscle were identified and counted. The diameter of the neurovascular pedicle was measured just before its entrance into the semitendinosus muscle...
March 2018: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/29644092/the-grafts-modified-by-heparinization-and-catalytic-nitric-oxide-generation-used-for-vascular-implantation-in-rats
#17
Jingchen Gao, Li Jiang, Qinge Liang, Jie Shi, Ding Hou, Di Tang, Siyuan Chen, Deling Kong, Shufang Wang
Small-diameter (<6 mm) vascular grafts are increasingly needed in peripheral vascular surgery but have few successes because of acute thrombosis, incomplete endothelialization and intimal hyperplasia after implantation. This study used electrospun poly(ε-caprolactone) as the matrix material. Heparin and selenium-containing catalyst-organoselenium modified polyethyleneimine were introduced through layer-by-layer assembly in order to build a vascular graft with in situ nitric oxide (NO) generation. The aim of this study was to explore the application of the graft with improved histocompatibility and biological function for vascular implantation in rats...
March 2018: Regenerative Biomaterials
https://www.readbyqxmd.com/read/29643181/smooth-muscle-cells-differentiated-from-human-mesenchymal-stem-cells-regulated-by-microrna-mir-503-and-mir-222-5p-are-suitable-for-vascular-tissue-engineering
#18
Wenduo Gu, Xuechong Hong, Alexandra Le Bras, Witold N Nowak, Shirin Issa Bhaloo, Jiacheng Deng, Yao Xie, Yanhua Hu, Xiong Z Ruan, Qingbo Xu
Tissue-engineered vascular grafts with long-term patency are greatly needed in the clinical settings, and smooth muscle cells (SMCs) are a critical graft component. Human mesenchymal stem cells (MSCs) are used for generating SMCs and understanding the underlying regulatory mechanisms of the MSC-to-SMC differentiation process could improve SMC generation in the clinic. Here, we found that in response to stimulation of transforming growth factor-β 1 (TGFβ1), human umbilical cord-derived MSCs abundantly express the SMC markers α-smooth muscle actin (αSMA), smooth muscle protein 22 (SM22), calponin and smooth muscle myosin heavy chain (SMMHC) at both gene and protein levels...
April 11, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29643130/transcatheter-versus-surgical-aortic-valve-replacement-in-patients-with-prior-coronary-artery-bypass-grafting-trends-in-utilization-and-propensity-matched-analysis-of-in-hospital-outcomes
#19
Tanush Gupta, Sahil Khera, Dhaval Kolte, Kashish Goel, Ankur Kalra, Pedro A Villablanca, Herbert D Aronow, J Dawn Abbott, Gregg C Fonarow, Cynthia C Taub, Neal S Kleiman, Giora Weisz, Ignacio Inglessis, Sammy Elmariah, Charanjit S Rihal, Mario J Garcia, Deepak L Bhatt
BACKGROUND: A significant proportion of patients requiring aortic valve replacement (AVR) have undergone prior coronary artery bypass grafting (CABG). Reoperative heart surgery is associated with increased risk. Data on relative utilization and comparative outcomes of transcatheter (TAVR) versus surgical AVR (SAVR) in patients with prior CABG are limited. METHODS AND RESULTS: We queried the 2012 to 2014 National Inpatient Sample databases to identify isolated AVR hospitalizations in adults with prior CABG...
April 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29642730/long-term-outcomes-of-bovine-pericardial-patch-angioplasty-for-recurrent-stenosis-in-vascular-access-a-uk-single-centre-experience
#20
Owain Fisher, Lewis Meecham, Pauline Buxton, Jocelyn Legge, Jack Fairhead, Sriram Rajagopalan, John Asquith, Arun Pherwani
INTRODUCTION: Stenosis of an arteriovenous fistula or arteriovenous graft for dialysis is a common problem. Stenosis may lead to a number of problems including failure of the fistula. Treatment of stenosis is commonly with percutaneous angioplasty or surgical patch angioplasty with autologous vein or synthetic graft or patch. Here we report the use of bovine pericardial patch angioplasty as an alternative mode of patch angioplasty when percutaneous intervention has failed. METHODS: Patients with fistulae treated with bovine patch angioplasty between 2013 and 2016 were identified from a prospectively maintained renal access database (Cyberren® )...
April 1, 2018: Journal of Vascular Access
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