Yuhang Wen, Yadan Luo, Hao Qiu, Baoting Chen, Jingrong Huang, Shuya Lv, Yan Wang, Jiabi Li, Lingling Tao, Bailin Yang, Ke Li, Lvqin He, Manli He, Qian Yang, Zehui Yu, Wudian Xiao, Mingde Zhao, Xiaoxia Zou, Ruilin Lu, Congwei Gu
INTRODUCTION: It is well-known that different populations and animals, even experimental animals with the same rearing conditions, differ in their susceptibility to obesity. The disparity in gut microbiota could potentially account for the variation in susceptibility to obesity. However, the precise impact of gut microbiota on gut metabolites and its subsequent influence on susceptibility to obesity remains uncertain. METHODS: In this study, we established obesity-prone (OP) and obesity-resistant (OR) mouse models by High Fat Diet (HFD)...
2024: Frontiers in Microbiology