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https://www.readbyqxmd.com/read/28108729/comparative-omega-3-fatty-acid-enrichment-of-egg-yolks-from-first-cycle-laying-hens-fed-flaxseed-oil-or-ground-flaxseed
#1
I J Ehr, M E Persia, E A Bobeck
When laying hen diets are enriched with omega-3 polyunsaturated fatty acids to generate value-added eggs for human consumption markets, concentrations of alpha-linolenic (ALA), eicosapentaenoic (EPA), and docosahexaenoic acids (DHA) in the yolk can reach 250 mg/50 g whole egg. Flaxseed, a rich source of ALA, is commonly used for omega-3 enrichment; however, the impact of dietary flaxseed source (extracted oil vs. milled seed) on fatty acid transfer to egg yolk in laying hens is unknown. Therefore, transfer of ALA, EPA, and DHA into egg yolk from extracted flaxseed oil or milled flaxseed was evaluated in Hy-Line W-36 laying hens over an 8-week feeding period (25 to 33 wk old)...
January 20, 2017: Poultry Science
https://www.readbyqxmd.com/read/28108339/transcriptome-analysis-of-the-effect-of-polyunsaturated-fatty-acids-against-vibrio-vulnificus-infection-in-oreochromis-niloticus
#2
Chieh-Yu Pan, Yu-Hao Liu, Hong-Yi Gong, Jyh-Yih Chen
Vibrio vulnificus infection causes severe economic losses in Oreochromis niloticus aquaculture by inducing pro-inflammatory cytokines, that lead to inflammation and mortality. Omega-3 fatty acids, such as Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA), have been reported for their anti-inflammatory and antibacterial abilities in murine and zebrafish models. However, the anti-inflammatory and antibacterial functions of DHA and EPA in commercial aquaculture organisms such as Oreochromis niloticus remain unknown...
January 17, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28107816/the-time-course-of-erythrocyte-membrane-fatty-acid-concentrations-during-and-after-treatment-of-non-human-primates-with-increasing-doses-of-an-omega-3-rich-phospholipid-preparation-derived-from-krill-oil
#3
Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo, Yong-Fu Xiao
BACKGROUND: A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the omega-3 index changes it follows that the relative fractions of other fatty acids in the membrane are also changed. In the present study, increasing doses of a preparation of omega-3 rich phospholipids extracted from krill oil were administered orally to non-human primates for 12 weeks and the time course of EPA, DHA and 22 other fatty acids in erythrocytes was determined bi-weekly during treatment and for 8 weeks after cessation of treatment...
January 21, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28101948/influence-of-the-marine-feeding-area-on-the-muscle-and-egg-fatty-acid-composition-of-atlantic-salmon-salmo-salar-spawners-estimated-from-the-scale-stable-isotopes
#4
J Torniainen, M J Kainz, R I Jones, M Keinänen, P J Vuorinen, M Kiljunen
Fatty acids in muscle tissue and eggs of female Atlantic salmon Salmo salar spawners were analysed to evaluate the dietary quality of their final feeding areas in the Baltic Sea. The final likely feeding area was identified by comparing stable carbon and nitrogen isotope composition of the outermost growth region (final annulus) of scales of returned S. salar with that of reference S. salar caught from different feeding areas. Some overlap of stable-isotope reference values among the three areas, in addition to prespawning fasting, decreased the ability of muscle tri-acylglycerols to discriminate the final likely feeding area and the area's dietary quality...
January 18, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28098048/folate-and-vitamin-b12-concentrations-are-associated-with-plasma-dha-and-epa-fatty-acids-in-european-adolescents-the-healthy-lifestyle-in-europe-by-nutrition-in-adolescence-helena-study
#5
I Iglesia, I Huybrechts, M González-Gross, T Mouratidou, J Santabárbara, V Chajès, E M González-Gil, J Y Park, S Bel-Serrat, M Cuenca-García, M Castillo, M Kersting, K Widhalm, S De Henauw, M Sjöström, F Gottrand, D Molnár, Y Manios, A Kafatos, M Ferrari, P Stehle, A Marcos, F J Sánchez-Muniz, L A Moreno
This study aimed to examine the association between vitamin B6, folate and vitamin B12 biomarkers and plasma fatty acids in European adolescents. A subsample from the Healthy Lifestyle in Europe by Nutrition in Adolescence study with valid data on B-vitamins and fatty acid blood parameters, and all the other covariates used in the analyses such as BMI, Diet Quality Index, education of the mother and physical activity assessed by a questionnaire, was selected resulting in 674 cases (43 % males). B-vitamin biomarkers were measured by chromatography and immunoassay and fatty acids by enzymatic analyses...
January 18, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28094560/systemic-metabolite-changes-in-wild-type-c57bl-6-mice-fed-black-raspberries
#6
Pan Pan, Chad W Skaer, Hsin-Tzu Wang, Michael A Kreiser, Steven M Stirdivant, Kiyoko Oshima, Yi-Wen Huang, Matthew R Young, Li-Shu Wang
INTRODUCTION: Freeze-dried black raspberries (BRBs) elicit chemopreventive effects against colorectal cancer in humans and in rodents. The objective of this study was to investigate potential BRB-caused metabolite changes using wild-type (WT) C57BL/6 mice. METHODS AND RESULTS: WT mice were fed either control diet or control diet supplemented with 5% BRBs for 8 wk. A nontargeted metabolomic analysis was conducted on colonic mucosa, liver, and fecal specimens collected from both diet groups...
January 17, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28089858/glucose-amino-acids-and-fatty-acids-directly-regulate-ghrelin-and-nucb2-nesfatin-1-in-the-intestine-and-hepatopancreas-of-goldfish-carassius-auratus-in-vitro
#7
Juan Ignacio Bertucci, Ayelén Melisa Blanco, Luis Fabián Canosa, Suraj Unniappan
Ghrelin and nesfatin-1 are two peptidyl hormones primarily involved in food intake regulation. We previously reported that the amount of dietary carbohydrates, protein and lipids modulates the expression of these peptides in goldfish in vivo. In the present work, we aimed to characterize the effects of single nutrients on ghrelin and nesfatin-1 in the intestine and hepatopancreas. First, immunolocalization of ghrelin and NUCB2/nesfatin-1 in goldfish hepatopancreas cells was studied by immunohistochemistry. Second, the effects of 2 and 4hour-long exposures of cultured intestine and hepatopancreas sections to glucose, l-tryptophan, oleic acid, linolenic acid (LNA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on ghrelin and nesfatin-1 gene and protein expression were studied...
January 13, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28089169/the-role-of-n-3-polyunsaturated-fatty-acids-n-3pufas-in-affective-disorders
#8
REVIEW
Valentina Ciappolino, Giuseppe Delvecchio, Carlo Agostoni, Alessandra Mazzocchi, Alfredo Carlo Altamura, Paolo Brambilla
BACKGROUND: Among emerging treatments for depressive disorders several studies suggested that n-3 polyunsaturated fatty acids (n-3PUFAs) supplementation can be used. However, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) differ in terms of biochemistry, metabolism and therapeutic effects. Therefore, a clear picture of their specific and different role on affective disorders has not yet emerged. OBJECTIVES: To investigate the effects of n-3PUFAs on affective disorders including major depression, bipolar disorder and perinatal depression...
December 30, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28088291/bcfa-suppresses-lps-induced-il-8-mrna-expression-in-human-intestinal-epithelial-cells
#9
Y Yan, Z Wang, J Greenwald, K S D Kothapalli, H G Park, R Liu, E Mendralla, P Lawrence, X Wang, J T Brenna
Branched chain fatty acids (BCFA) are components of common food fats and are major constituents of the normal term human newborn GI tract. Polyunsaturated fatty acids (PUFA) have been suggested to reduce the risk and development of inflammatory bowel diseases (IBD); however, little is known about the influence of BCFA on inflammation. We investigated the effect of BCFA on interleukin (IL)-8 and NF-κB production in a human intestinal epithelial cell line (Caco-2). Cells were pre-treated with specific BCFA, or DHA, or EPA, and then activated with lipopolysaccharide (LPS)...
January 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28078500/effects-of-different-omega-3-sources-fish-oil-krill-oil-and-green-lipped-mussel-against-cytokine-mediated-canine-cartilage-degradation
#10
Kittisak Buddhachat, Puntita Siengdee, Siriwadee Chomdej, Kumpanart Soontornvipart, Korakot Nganvongpanit
Our purpose was to evaluate the protective effect of three marine omega-3 sources, fish oil (FO), krill oil (KO), and green-lipped mussel (GLM) against cartilage degradation. Canine cartilage explants were stimulated with either 10 ng/mL interleukin-1β (IL-1β) or IL-1β/oncostatin M (10 ng/mL each) and then treated with various concentrations of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA; 3 and 30 μg/mL), FO, KO, or GLM (250, 500, and 1000 μg/mL) for 28 days. Gene expression was then investigated in primary canine chondrocytes...
January 11, 2017: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28078253/effects-of-eicosapentaenoic-acid-and-docosahexaenoic-acid-on-mitochondrial-dna-replication-and-pgc-1%C3%AE-gene-expression-in-c2c12-muscle-cells
#11
Mak-Soon Lee, Yoonjin Shin, Sohee Moon, Seunghae Kim, Yangha Kim
Mitochondrial biogenesis is a complex process requiring coordinated expression of nuclear and mitochondrial genomes. The peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α) is a key regulator of mitochondrial biogenesis, and it controls mitochondrial DNA (mtDNA) replication within diverse tissues, including muscle tissue. The aim of this study was to investigate the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on mtDNA copy number and PGC-1α promoter activity in C2C12 muscle cells...
December 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28075381/the-n-3-polyunsaturated-fatty-acids-supplementation-improved-the-cognitive-function-in-the-chinese-elderly-with-mild-cognitive-impairment-a-double-blind-randomized-controlled-trial
#12
Yacong Bo, Xueyuan Zhang, Youli Wang, Jie You, Han Cui, Yiwei Zhu, Wei Pang, Wei Liu, Yugang Jiang, Quanjun Lu
OBJECTIVE: Intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) may protect against mild cognitive impairment (MCI). However, there is still a lack of the n-3 PUFAs intervention in the elderly with MCI in China. The aim of the present study was to investigate the effect of n-3 PUFA supplementation on cognitive function in the Chinese elderly with MCI. METHODS: Eighty six MCI individuals aged 60 years or older were randomly assigned to receive either n-3 PUFAs (480 mg DHA and 720 mg EPA per day, n = 44) or placebo (olive oil, n = 42) capsules...
January 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28075380/splenic-immune-response-is-down-regulated-in-c57bl-6j-mice-fed-eicosapentaenoic-acid-and-docosahexaenoic-acid-enriched-high-fat-diet
#13
Nikul K Soni, Alastair B Ross, Nathalie Scheers, Otto I Savolainen, Intawat Nookaew, Britt G Gabrielsson, Ann-Sofie Sandberg
Dietary n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with reduction of inflammation, although the mechanisms are poorly understood, especially how the spleen, as a secondary lymphoid organ, is involved. To investigate the effects of EPA and DHA on spleen gene expression, male C57BL/6J mice were fed high fat diets (HFD) differing in fatty acid composition, either based on corn oil (HFD-CO), or CO enriched with 2 g/100 g EPA and DHA (HFD-ED), for eight weeks. Spleen tissue was analyzed using transcriptomics and for fatty acids profiling...
January 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28069365/polyunsaturated-fatty-acids-and-recurrent-mood-disorders-phenomenology-mechanisms-and-clinical-application
#14
REVIEW
Erik Messamore, Daniel M Almeida, Ronald J Jandacek, Robert K McNamara
A body of evidence has implicated dietary deficiency in omega-3 polyunsaturated fatty acids (n-3 PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in the pathophysiology and etiology of recurrent mood disorders including major depressive disorder (MDD) and bipolar disorder. Cross-national and cross-sectional evidence suggests that greater habitual intake of n-3 PUFA is associated with reduced risk for developing mood symptoms. Meta-analyses provide strong evidence that patients with mood disorders exhibit low blood n-3 PUFA levels which are associated with increased risk for the initial development of mood symptoms in response to inflammation...
January 6, 2017: Progress in Lipid Research
https://www.readbyqxmd.com/read/28062061/a-meta-analysis-of-randomized-controlled-trials-and-prospective-cohort-studies-of-eicosapentaenoic-and-docosahexaenoic-long-chain-omega-3-fatty-acids-and-coronary-heart-disease-risk
#15
Dominik D Alexander, Paige E Miller, Mary E Van Elswyk, Connye N Kuratko, Lauren C Bylsma
OBJECTIVE: To conduct meta-analyses of randomized controlled trials (RCTs) to estimate the effect of eicosapentaenoic and docosahexaenoic acid (EPA+DHA) on coronary heart disease (CHD), and to conduct meta-analyses of prospective cohort studies to estimate the association between EPA+DHA intake and CHD risk. METHODS: A systematic literature search of Ovid/Medline, PubMed, Embase, and the Cochrane Library from January 1, 1947, to November 2, 2015, was conducted; 18 RCTs and 16 prospective cohort studies examining EPA+DHA from foods or supplements and CHD, including myocardial infarction, sudden cardiac death, coronary death, and angina, were identified...
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28053574/evaluation-of-different-commercial-feeds-on-grow-out-silver-black-porgy-sparidentex-hasta-valenciennes-for-optimum-growth-performance-fillet-quality-and-cost-of-production
#16
M A Hossain, K M Al-Abdul-Elah, S El-Dakour
The objective of the study was to find a cost-effective feed from three commercial feeds, namely, Arasco (Saudi Arabia), Skretting (Turkey), and Biomar (Greece) for commercially producing silver black porgy (sobaity bream), Sparidentex hasta in Kuwait. For confidentiality, these feeds were randomly given code names, diets 1, 2, and 3, which were known only to the investigating staffs. The trash fish (diet 4) was used as the control. The experiment was conducted for 28 wk with grow-out sobaity bream (210.0 ± 0...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28041934/benefit-risk-ratio-of-canned-pacific-saury-cololabis-saira-intake-essential-fatty-acids-vs-heavy-metals
#17
O V Anishchenko, N N Sushchik, O N Makhutova, G S Kalachova, I V Gribovskaya, V N Morgun, M I Gladyshev
Fatty acid (FA) and element contents were studied in 14 brands of canned (in its own juice and with sunflower oil) saury (Cololabis saira), a popular product of Russian market. Canned saury is a valuable source of essential polyunsaturated FA - eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). To obtain personal daily dose of EPA + DHA of 1 g for prevention of cardiovascular diseases, neural and inflammatory disorders one needs to intake from 26 to 76 g of canned saury, as was calculated for studied brands...
December 29, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28033525/dietary-polychlorinated-biphenyls-long-chain-n-3-polyunsaturated-fatty-acids-and-incidence-of-malignant-melanoma
#18
Carolina Donat-Vargas, Marika Berglund, Anders Glynn, Alicja Wolk, Agneta Åkesson
BACKGROUND: For malignant melanoma, other risk factors aside from sun exposure have been hardly explored. Polychlorinated biphenyls (PCBs)-mainly from fatty fish- may affect melanogenesis and promote melanoma progression, while long-chain n-3 polyunsaturated fatty acids seem to exert antineoplastic actions in melanoma cells. OBJECTIVES: We aimed to assess the association of validated estimates of dietary PCB exposure as well as the intake of eicosapentaenoic acid and docosahexaenoic acid (EPA-DHA), accounting for sun habits and skin type, with the risk of malignant melanoma in middle-aged and elderly women...
December 26, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28031376/vitamin-b-6-status-in-unsupplemented-pregnant-women-is-associated-positively-with-serum-docosahexaenoic-acid-and-inversely-with-the-n-6-to-n-3-fatty-acid-ratio
#19
Maria F Mujica-Coopman, Ana B Franco-Sena, Dayana R Farias, Juliana S Vaz, Alex Brito, Gilberto Kac, Yvonne Lamers
BACKGROUND: Vitamin B-6-deficient diets decrease plasma docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and arachidonic acid (AA) concentrations in healthy adults. These fatty acids (FAs) are important for fetal neurodevelopment, but the relation between vitamin B-6 status and circulating polyunsaturated FAs (PUFAs) during pregnancy is unknown. OBJECTIVE: We sought to assess the relation between plasma pyridoxal 5' phosphate (PLP; the active form of vitamin B-6) and serum DHA, EPA, AA, linoleic acid, eicosadienoic, and α-linolenic acid concentrations during pregnancy...
December 28, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/28028455/whole-genome-single-nucleotide-polymorphism-snp-marker-discovery-and-association-analysis-with-the-eicosapentaenoic-acid-epa-and-docosahexaenoic-acid-dha-content-in-larimichthys-crocea
#20
Shijun Xiao, Panpan Wang, Linsong Dong, Yaguang Zhang, Zhaofang Han, Qiurong Wang, Zhiyong Wang
Whole-genome single-nucleotide polymorphism (SNP) markers are valuable genetic resources for the association and conservation studies. Genome-wide SNP development in many teleost species are still challenging because of the genome complexity and the cost of re-sequencing. Genotyping-By-Sequencing (GBS) provided an efficient reduced representative method to squeeze cost for SNP detection; however, most of recent GBS applications were reported on plant organisms. In this work, we used an EcoRI-NlaIII based GBS protocol to teleost large yellow croaker, an important commercial fish in China and East-Asia, and reported the first whole-genome SNP development for the species...
2016: PeerJ
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