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https://www.readbyqxmd.com/read/27904870/preclinical-study-of-68-ga-dotatoc-biodistribution-assessment-in-syrian-rats-and-evaluation-of-absorbed-dose-in-human-organs
#1
Mojdeh Naderi, Samaneh Zolghadri, Hassan Yousefnia, Ali Ramazani, Amir Reza Jalilian
OBJECTIVES: Gallium-68 DOTA-DPhe(1)-Tyr(3)-Octreotide ((68)Ga-DOTATOC) has been applied by several European centers for the treatment of a variety of human malignancies. Nevertheless, definitive dosimetric data are yet unavailable. According to the Society of Nuclear Medicine and Molecular Imaging, researchers are investigating the safety and efficacy of this radiotracer to meet Food and Drug Administration requirements. The aim of this study was to introduce the optimized procedure for (68)Ga-DOTATOC preparation, using a novel germanium-68 ((68)Ge)/(68)Ga generator in Iran and evaluate the absorbed doses in numerous organs with high accuracy...
2016: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/27903839/the-effect-of-brain-tomography-findings-on-mortality-in-sniper-shot-head-injuries
#2
Çağdaş Can, M Bolatkale, A Sarıhan, Y Savran, A Ç Acara, M Bulut
OBJECTIVES: Penetrating gunshot head injuries have a poor prognosis and require prompt care. Brain CT is a routine component of the standard evaluation of head wounds and suspected brain injury. We aimed to investigate the effect of brain CT findings on mortality in gunshot head injury patients who were admitted to our emergency department (ED) from the Syrian Civil War. METHODS: The study group comprised patients who were admitted to the ED with gunshot brain injury...
November 30, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27896416/prevalence-of-isolated-maxillary-lateral-incisor-agenesis-in-syrian-adolescents
#3
Tamouh Kabbani, Nagham Abdullah, Yasser Rsheadat, Mohamed Ibrahim Abu Hassan
PURPOSE: This research is designed to obtain a better understanding and provide more insight of this phenomenon through evaluating the prevalence of congenital absence of maxillary lateral incisors in a Syrian population. METHODS: The method involved clinical examination of 8000 school children with an equal number of males and females (age range 12-15 years) to identify students only affected by bilateral or unilateral congenital absence of maxillary lateral incisors...
November 28, 2016: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/27890485/nizar-albache-championing-the-cause-of-syrian-refugees-with-diabetes
#4
Jennifer Thorley
No abstract text is available yet for this article.
November 24, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27889328/multiple-spontaneous-coronary-artery-dissections-an-uncommon-cause-of-acute-coronary-syndrome-in-a-syrian-refugee
#5
Tina Zhu, Peggy DeJong, Amer M Johri
Spontaneous coronary artery dissection is an uncommon nonatherosclerotic cause of acute coronary syndrome. It usually occurs in young women and is often associated with fibromuscular dysplasia, connective tissue diseases, and pregnancy or postpartum states. We present a case of a Syrian woman with a history of grand multiparity and recent miscarriage who presented with non-ST-elevation myocardial infarction and was found to have multivessel spontaneous coronary artery dissection and severe left ventricular dysfunction...
August 24, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27884856/a-refugee-camp-in-the-centre-of-europe-clinical-characteristics-of-asylum-seekers-arriving-in-brussels
#6
Gerlant van Berlaer, Francisca Bohle Carbonell, Sofie Manantsoa, Xavier de Béthune, Ronald Buyl, Michel Debacker, Ives Hubloue
BACKGROUND: In the summer of 2015, the exodus of Syrian war refugees and saturation of refugee camps in neighbouring countries led to the influx of asylum-seekers in European countries, including Belgium. This study aims to describe the demographic and clinical characteristics of asylum seekers who arrived in a huddled refugee camp, in the centre of a well-developed country with all medical facilities. METHODS: Using a descriptive cross-sectional study design, physicians of Médecins du Monde prospectively registered age, gender, origin, medical symptoms and diagnoses of all patients presenting to an erected field hospital in Brussels in September 2015...
November 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27881648/modeling-severe-fever-with-thrombocytopenia-syndrome-virus-infection-in-golden-syrian-hamsters-importance-of-stat2-in-preventing-disease-and-effective-treatment-with-favipiravir
#7
Brian B Gowen, Jonna B Westover, Jinxin Miao, Arnaud J Van Wettere, Johanna D Rigas, Brady T Hickerson, Kie-Hoon Jung, Rong Li, Bettina L Conrad, Skot Nielson, Yousuke Furuta, Zhongde Wang
: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease endemic in parts of Asia. The etiologic agent, SFTS virus (SFTSV; Bunyaviridae family, Phlebovirus genus) has caused significant morbidity and mortality in China, Korea, and Japan, with key features of disease being intense fever, thrombocytopenia, and leukopenia. Case fatality rates are estimated in the 30% range and no antivirals or vaccines are approved for use for treatment and prevention of SFTS...
November 23, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27876089/rapid-onset-obesity-hypoventilation-hypothalamic-dysfunction-autonomic-dysregulation-and-neuroendocrine-tumor-syndrome-with-a-homogenous-enlargement-of-the-pituitary-gland-a-case-report
#8
Lama Aljabban, Lina Kassab, Nour Alhuda Bakoura, Mohammad Fayez Alsalka, Ismaeil Maksoud
BACKGROUND: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation syndrome is a rare pediatric disorder with a variable sequence of clinical presentations, undefined etiology, and high risk of mortality. Our patient presented an unusual course of the disease accompanied by a homogenous mild enlargement of her pituitary gland with an intact pituitary-endocrine axis which, to the best of our knowledge, represents a new finding in rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation syndrome...
November 22, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27872656/nutritional-situation-among-syrian-refugees-hosted-in-iraq-jordan-and-lebanon-cross-sectional-surveys
#9
S M Moazzem Hossain, Eva Leidman, James Kingori, Abdullah Al Harun, Oleg O Bilukha
BACKGROUND: Ongoing armed conflict in Syria has caused large scale displacement. Approximately half of the population of Syria have been displaced including the millions living as refugees in neighboring countries. We sought to assess the health and nutrition of Syrian refugees affected by the conflict. METHODS: Representative cross-sectional surveys of Syrian refugees were conducted between October 2 and November 30, 2013 in Lebanon, April 12 and May 1, 2014 in Jordan, and May 20 and 31, 2013 in Iraq...
2016: Conflict and Health
https://www.readbyqxmd.com/read/27870445/evaluating-social-defeat-as-a-model-for-psychopathology-in-adult-female-rodents
#10
REVIEW
Matia B Solomon
Social conflict is a predominant stressor in humans and is associated with increased risk for developing psychological illnesses including depression and anxiety. Overwhelmingly, more women suffer from these disorders, which may be due to increased stress sensitivity. Like humans, rodents experience a myriad of physiological and behavioral sequelae due to prolonged stress exposure. Although the motivation for social conflict may differ between humans and rodents, female rodents may provide an opportunity to explore the underlying mechanisms by which stress confers risk for psychopathology in women...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27848937/reconstructing-druze-population-history
#11
Scarlett Marshall, Ranajit Das, Mehdi Pirooznia, Eran Elhaik
The Druze are an aggregate of communities in the Levant and Near East living almost exclusively in the mountains of Syria, Lebanon and Israel whose ~1000 year old religion formally opposes mixed marriages and conversions. Despite increasing interest in genetics of the population structure of the Druze, their population history remains unknown. We investigated the genetic relationships between Israeli Druze and both modern and ancient populations. We evaluated our findings in light of three hypotheses purporting to explain Druze history that posit Arabian, Persian or mixed Near Eastern-Levantine roots...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27847016/low-prevalence-of-hepatitis-b-and-c-among-tuberculosis-patients-in-duhok-province-kurdistan-are-hbsag-and-anti-hcv-prerequisite-screening-parameters-in-tuberculosis-control-program
#12
Muayad A Merza, Safer M Haji, Abid Mohialdeen Hasan Alsharafani, Shivan U Muhammed
OBJECTIVE/BACKGROUND: Viral hepatitis, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), infections and tuberculosis (TB) are a global public health concern. Co-infection with HBV or HCV among TB patients may potentiate the risk of hepatotoxicity induced by anti-TB drugs. Hence, the aim of this study was to identify the prevalence of HBV and HCV among TB patients included in the Duhok National Tuberculosis Program (NTP). METHODS: The Duhok NTP Center is a specialized institution in Duhok City, Iraq, concerned with management and follow-up of TB patients...
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27824227/topical-application-of-sulfotanshinone-sodium-suppresses-sebaceous-hyperplasia-in-syrian-hamsters
#13
Maya V Gozali, Bingrong Zhou, Fei Yi, Yang Xu, Dan Luo
No abstract text is available yet for this article.
December 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27812087/identifying-early-target-cells-of-nipah-virus-infection-in-syrian-hamsters
#14
Laura Baseler, Dana P Scott, Greg Saturday, Eva Horne, Rebecca Rosenke, Tina Thomas, Kimberly Meade-White, Elaine Haddock, Heinz Feldmann, Emmie de Wit
BACKGROUND: Nipah virus causes respiratory and neurologic disease with case fatality rates up to 100% in individual outbreaks. End stage lesions have been described in the respiratory and nervous systems, vasculature and often lymphoid organs in fatal human cases; however, the initial target organs of Nipah virus infection have not been identified. Here, we detected the initial target tissues and cells of Nipah virus and tracked virus dissemination during the early phase of infection in Syrian hamsters inoculated with a Nipah virus isolate from Malaysia (NiV-M) or Bangladesh (NiV-B)...
November 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27810703/histone-deacetylase-and-acetyltransferase-inhibitors-modulate-behavioral-responses-to-social-stress
#15
Katharine E McCann, Anna M Rosenhauer, Genna M F Jones, Alisa Norvelle, Dennis C Choi, Kim L Huhman
Histone acetylation has emerged as a critical factor regulating learning and memory both during and after exposure to stressful stimuli. There are drugs that we now know affect histone acetylation that are already in use in clinical populations. The current study uses these drugs to examine the consequences of acutely increasing or decreasing histone acetylation during exposure to social stress. Using an acute model of social defeat in Syrian hamsters, we systemically and site-specifically administered drugs that alter histone acetylation and measured subsequent behavior and immediate-early gene activity...
January 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27807231/replicating-single-cycle-adenovirus-vectors-generate-amplified-influenza-vaccine-responses
#16
Catherine M Crosby, William E Matchett, Stephanie S Anguiano-Zarate, Christopher A Parks, Eric A Weaver, Larry R Pease, Richard J Webby, Michael A Barry
: Head to head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrate these viral vectors can mediate more potent protection against influenza infection in animal models. In most cases, Ad vaccines are engineered to be replication defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent, but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication, but avoid production of infectious virions, we developed "single cycle" adenovirus (SC-Ad) vectors...
November 2, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27800018/endoscopic-removal-of-a-retained-surgical-sponge-in-a-young-syrian-refugee-after-caesarean-section-a-case-report-with-discussion-of-cultural-and-political-consequences
#17
Johannes Ackermann, Moritz Kanzow, Micaela Mathiak, Ulrich Pecks, Nicolai Maass, Ibrahim Alkatout
BACKGROUND: Inadvertently retained sponges and instruments still constitute a major but preventable complication in surgery. Given the high geographic mobility of patients, the fluctuation of physician-patient contact, and communication problems due to language barriers, the conscientious use of structured safety protocols in clinical routine is an essential aspect of quality in health care. CASE PRESENTATION: We report the case of a 24-year-old refugee from Syria who presented at our gynecological outpatient department with a tumor in the lower abdomen, suspected to be a lump in the ovary or the uterus...
2016: Patient Safety in Surgery
https://www.readbyqxmd.com/read/27798992/a-compounding-mental-health-crisis-reflections-from-the-greek-experience-with-syrian-refugees
#18
Dimitris C Anagnostopoulos, George Giannakopoulos, Nikos G Christodoulou
No abstract text is available yet for this article.
November 1, 2016: American Journal of Psychiatry
https://www.readbyqxmd.com/read/27797281/acute-kidney-function-and-morphology-following-topload-administration-of-recombinant-hemoglobin-solution
#19
Alexandre Fabricio Martucci, Ana Carolina Carvalho Ferreira Abreu Martucci, Pedro Cabrales, Paulo do Nascimento, Marcos Intaglietta, Amy G Tsai, Yara Marcondes Machado Castiglia
There is a 0.138% incidence of adverse reactions related to blood transfusion. Transfusion-related acute lung injury, immunosuppression, fever, pathogen transmission, and hemolytic transfusion reactions are the most common ones. Synthetic oxygen carriers have been developed to deal with blood shortages and for use in the field where stored blood was not available. They were also designed to be pathogen free, including unknown viruses. In this study, we used Male Golden Syrian Hamsters implemented with a dorsal window chamber to determine how infusion of three different, genetically crosslinked recombinant acellular hemoglobin (rHb) solutions with different oxygen affinities and nitric oxide kinetics affect mean arterial pressure (MAP), heart rate (HR), kidney function, and kidney structure...
October 31, 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/27797227/incidence-and-mortality-of-testicular-cancer-and-relationships-with-development-in-asia
#20
Mostafa Sadeghi, Mahshid Ghoncheh, Abdollah Mohammadian-Hafshejani, Hamidreza Sadeghi Gandomani, Hosein Rafiemanesh, Hamid Salehiniya
BACKGROUND: Testicular cancer is one of the most common cancers among young men between ages 20-34 in countries with high or very high levels of the Human Development Index (HDI). This study investigated the incidence and mortality of prostate cancer and the relationship with the HDI and its dimensions in Asia in 2012. MATERIALS AND METHODS: The study was conducted based on data from the world data of cancer and the World Bank (including the HDI and its components)...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
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