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https://www.readbyqxmd.com/read/28898794/surgical-management-of-late-bullet-embolization-from-the-abdomen-to-the-right-ventricle-case-report
#1
Ramos Mayo Alan Elison, Diaz Elizondo Jose Antonio, Segura Marin Hector, Lopez Garnica Dolores, Treviño Garza Francisco Xavier
INTRODUCTION: Secondary embolus from gun projectile is a rare entity, it represents a clinical and therapeutic dilemma because the potential complications involving central and peripheral circulation. Each case reported in the literature represents a challenge because their unique and different clinical scenarios. PRESENTATION OF CASE: We present the management of a 33-year-old man with past history of a gunshot wound on left flank with no evidence of any exit wounds, treated with exploratory laparotomy without removing the gunshot bullet from the abdomen...
September 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28888336/pediatric-firearm-deaths-and-injuries-in-the-united-states
#2
Deborah L McBride
Guns are the third leading cause of death of those aged 1 to 17years, outpaced only by unintentional injuries such as car crashes and drowning, and illnesses like cancer according to a new federal study. The new study, which has been called the most comprehensive examination of current firearms-related deaths and injury among children in the United States used data from the National Electronic Injury Surveillance System and the Centers for Disease Control and Prevention (CDC) National Violent Death Reporting System to assess the magnitude and characteristics of firearm-related deaths and injuries among children (age 0-17years) from 2002 to 2014...
September 6, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28876574/holding-the-torch-up-high-a-medical-historical-evaluation-of-surgical-advances-during-the-great-war-1914-1918-in-memory-of-those-that-served-and-fell
#3
G Scharf
"How wide and varied is the experience of the battlefield and how fertile the blood of warriors in raising good surgeons" Sir Clifford Allbutt (1898). With these sentiments of the medical lessons learned in war and conflict, with the background of the poem of "In Flanders Field", written by a doctor who had South African War connections, reasons (the Somme and third Ypres battles) will be given that this was indeed a "GREAT WAR" as the world history, weapons, strategy, tactics and wounding patterns had changed dramatically...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28873453/satellite-tagging-of-rehabilitated-green-sea-turtles-chelonia-mydas-from-the-united-arab-emirates-including-the-longest-tracked-journey-for-the-species
#4
David P Robinson, Rima W Jabado, Christoph A Rohner, Simon J Pierce, Kevin P Hyland, Warren R Baverstock
We collected movement data for eight rehabilitated and satellite-tagged green sea turtles Chelonia mydas released off the United Arab Emirates between 2005 and 2013. Rehabilitation periods ranged from 96 to 1353 days (mean = 437 ± 399 days). Seven of the eight tagged turtles survived after release; one turtle was killed by what is thought to be a post-release spear gun wound. The majority of turtles (63%) used shallow-water core habitats and established home ranges between Dubai and Abu Dhabi, the same area in which they had originally washed ashore prior to rescue...
2017: PloS One
https://www.readbyqxmd.com/read/28853319/fabrication-and-characterization-of-phlorotannins-poly-vinyl-alcohol-hydrogel-for-wound-healing-application
#5
Hyeon-Ho Park, Seok-Chun Ko, Gun-Woo Oh, Soo-Jin Heo, Do-Hyung Kang, Sung-Yong Bae, Won-Kyo Jung
Phlorotannins (PH) derived from brown algae have been shown to have biological effects. However, the application of PH in biomedical materials has not been investigated. Here, we investigated the effects of PH on normal human dermal fibroblast (NHDF) proliferation and fabricated a composite hydrogel consisting PH and poly (vinyl alcohol) (PVA) (PVA/PH) by a freezing-thawing method for wound healing applications. Cell proliferation was significantly higher in the PH-treated (0.01 and 0.02%) cells than in non-treated cells...
August 30, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28747631/jmjd3-and-nf-%C3%AE%C2%BAb-dependent-activation-of-notch1-gene-is-required-for-keratinocyte-migration-during-skin-wound-healing
#6
Jungtae Na, Jee Yoon Shin, Hayan Jeong, Jee Youn Lee, Beom Joon Kim, Won Sun Kim, Tae Young Yune, Bong-Gun Ju
It has been shown that epigenetic regulation plays an important role in skin wound healing. We previously found that histone H3K27me3 demethylase JMJD3 regulates inflammation and cell migration in keratinocyte wound healing. In this study, we identified Notch1 as a direct target of JMJD3 and NF-κB in wounded keratinocytes using in vitro cell and in vivo animal models. We found that Notch1 is up-regulated in the wound edge and its expression is dependent on JMJD3 and NF-κB in wounded keratinocytes. We also found that Notch1 activates the expression of RhoU and PLAU gene, which are critical regulators of cell migration...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28717964/wound-morphology-in-contact-shots-from-blank-cartridge-handguns-a-study-on-composite-models
#7
Rebecca Pircher, Markus Große Perdekamp, Annette Thierauf-Emberger, Lena Kramer, Stefan Pollak, Dorothee Geisenberger
It is a well-known fact that blank cartridge guns can cause penetrating and even fatal injuries when discharged in contact or at very close ranges. In these cases, the gas jet perforates the skin leaving an entrance wound similar to that from a conventional gun. In order to investigate the wound morphology in contact shots from blank firearms, test shots were fired at composite models of pig skin and gelatin blocks using three different calibre 9-mm blank cartridge handguns (two pistols and one revolver) and two types of ammunition...
July 17, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28697020/good-news-bad-news-an-analysis-of-11-294-gunshot-wounds-gsws-over-two-decades-in-a-single-center
#8
Nathan R Manley, Timothy C Fabian, John P Sharpe, Louis J Magnotti, Martin A Croce
INTRODUCTION: Gun violence is a substantial public health problem accounting for significant physical, psychological and financial costs. While aggregate data sources demonstrate decreasing rates of firearm violence, analyses from individual trauma centers have shown that mortality and injury severity from GSWs are increasing. To evaluate the evolving characteristics of gun violence in our region, we studied all GSWs admitted to our trauma center over a twenty-year period. METHODS: A retrospective analysis of all newly admitted patients with GSWs was performed from 1996 to 2016...
July 8, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28684299/cyperus-amuricus-induces-g1-arrest-and-apoptosis-through-endoplasmic-reticulum-stress-and-mitochondrial-signaling-in-human-hepatocellular-carcinoma-hep3b-cells
#9
Hai Ha Thi Pham, Yeong-Ae Seong, Daniel Ngabire, Chul-Woong Oh, Gun-Do Kim
ETHNOPHARMACOLOGY RELEVANCE: Cyperus amuricus (C. amuricus), belongs to the family Cyperaceae, was used to exert wound healing, diuretic, astringent and other intestinal problems in oriental medicine. However, only a few studies have reported its anticancer activities. AIM OF THE STUDY: In this study, we determined the activity of C. amuricus on ER stress-induced cell death and G1 cell cycle arrest in human hepatocellular carcinoma (HCC) Hep3B cells. MATERIALS AND METHODS: The in vitro cell proliferation assay of C...
July 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28661608/-spongy-microporous-tampon-for-mechanical-clearance-of-a-gun-shot-wounos
#10
R N Mikhaylusov
Application of a spongy microporous tampon in accordance to technology elaborated was proposed for enhancement of the mechanical clearance efficacy of the gun-shot soft tissues wounds. A procedure of manufacturing and application of spongy microp- orous tampon for the mechanical clearance of a gun-shot wounds was depicted. The clearance efficacy was improved due to application of the method elaborated, wit- nessing possibility of its usage on all stages of the surgical aid delivery.
August 2016: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/28632556/watertight-sealing-without-lumbar-drainage-for-incidental-ventral-dural-defect-in-transthoracic-spine-surgery-a-retrospective-review-of-53-cases
#11
Sang-Hyeop Jeon, Sang-Ho Lee, Yi Sheng Tsang, Tag-Geun Jung, Ki-Hyoung Moon, Gun Choi, Ketan D Dilip
STUDY DESIGN: A retrospective review. OBJECTIVES: To evaluate the therapeutic efficacy of the triple layer closure technique to establish watertight sealing without diversion of lumbar drainage, in preventing persistent incidental subarachnoid-pleural fistula and other neurological complications related to excessive drainage of cerebrospinal fluid (CSF) after dural defect in transthoracic ossified posterior longitudinal ligament (OPLL) surgery. SUMMARY OF BACKGROUND DATA: CSF leakage into the pleural cavity leads to unfavorable conditions for natural healing of incidental durotomy due to the negative pressure environment of the pleural space and lack of wound healing around the bony cavity near the decompressed spinal cord...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28630118/childhood-firearm-injuries-in-the-united-states
#12
Katherine A Fowler, Linda L Dahlberg, Tadesse Haileyesus, Carmen Gutierrez, Sarah Bacon
OBJECTIVES: Examine fatal and nonfatal firearm injuries among children aged 0 to 17 in the United States, including intent, demographic characteristics, trends, state-level patterns, and circumstances. METHODS: Fatal injuries were examined by using data from the National Vital Statistics System and nonfatal injuries by using data from the National Electronic Injury Surveillance System. Trends from 2002 to 2014 were tested using joinpoint regression analyses. Incident characteristics and circumstances were examined by using data from the National Violent Death Reporting System...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28603241/-the-treatment-of-wounds-during-world-war-i
#13
Sergio Sabbatani, Sirio Fiorino
The First World War was a huge tragedy for mankind, but, paradoxically, it represented a source of significant progress in a broad series of human activities, including medicine, since it forced physicians to improve their knowledge in the treatment of a large number of wounded soldiers. The use of heavy artillery and machine guns, as well as chemical warfare, caused very serious and life-threatening lesions and wounds. The most frequent causes of death were not mainly related to gunshot wounds, but rather to fractures, tetanus and septic complications of infectious diseases...
June 1, 2017: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28598594/tethering-growth-factors-to-collagen-surfaces-using-copper-free-click-chemistry-surface-characterization-and-in-vitro-biological-response
#14
Hyun Jong Lee, Gabriella M Fernandes-Cunha, Ilham Putra, Won-Gun Koh, David Myung
Surface modifications with tethered growth factors have mainly been applied to synthetic polymeric biomaterials in well-controlled, acellular settings, followed by seeding with cells. The known bio-orthogonality of copper-free click chemistry provides an opportunity to not only use it in vitro to create scaffolds or pro-migratory tracks in the presence of living cells, but also potentially apply it to living tissues directly as a coupling modality in situ. In this study, we studied the chemical coupling of growth factors to collagen using biocompatible copper-free click chemistry and its effect on the enhancement of growth factor activity in vitro...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28498136/gunshot-wound-in-an-18-year-old-woman-inflicted-with-a-hunting-weapon-through-an-obstacle-mobile-phone-reconstruction-of-events
#15
Anna Smędra, Przemysław Sidelnik, Wojciech Goryca, Jarosław Berent
The article presents a case of an 18-year-old woman wounded by a shot fired from a distance with a hunting weapon. Because the location of the entrance and exit wounds initially seemed inconsistent with the reports (both wounds were described as "large and irregular in shape") and no photographs documenting the inflicted injuries were taken, the case was referred for an opinion to the Department of Forensic Medicine in Lodz. After a review of the medical records, radiology, the victim's clothing, and performance of an experiment using the gun and ammunition, it was established that the entrance wound was located on the abdomen, and the exit wound was located on the buttock...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28457327/an-epidemiologic-overview-of-13%C3%A2-years-of-firearm-hospitalizations-in-pennsylvania
#16
Brian W Gross, Alan D Cook, Cole D Rinehart, Caitlin A Lynch, Eric H Bradburn, Katherine A Bupp, Chet A Morrison, Frederick B Rogers
BACKGROUND: Gun violence is a controversial public health issue plagued by a lack of recent research. We sought to provide a 13-y overview of firearm hospitalizations in Pennsylvania, analyzing trends in mode, intent, and outcome. We hypothesized that no adjusted change in mortality or functional status at discharge (FSD) would be observed for gunshot wound (GSW) victims over the study period. METHODS: All admissions to the Pennsylvania Trauma Outcome Study database from 2003 to 2015 were queried...
April 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28448860/a-unique-presentation-of-renal-cell-transformation-into-renal-cell-carcinoma-in-subcutaneous-fatty-tissue-post-twenty-year-old-healing-gun-shot-wound-a-case-report
#17
Awadh R Alqahtani, Mohammed A Alqahtani
INTRODUCTION: Renal cell carcinoma (RCC) is the most common malignancy in the genitourinary tract, and is among the 10 most common cancers in both males and females. PRESENTATION OF CASE: We report a case of a 61-year-old male who presented with a cutaneous lesion on his left back side at a site where he had undergone several surgeries - including Left nephrectomy - twenty years ago for a gun-shot wound he sustained which penetrated his abdomen. DISCUSSION: At that time pathology reports turned out to be normal, specially left kidney pathology report which was negative for any malignancy...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28431393/loss-of-tpm4-1-leads-to-disruption-of-cell-cell-adhesions-and-invasive-behavior-in-breast-epithelial-cells-via-increased-rac1-signaling
#18
SukYeong Jeong, SunYoung Lim, Galina Schevzov, Peter W Gunning, David M Helfman
Here we report the identification and characterization of a novel high molecular weight isoform of tropomyosin, Tpm4.1, expressed from the human TPM4 gene. Tpm4.1 expression is down-regulated in a subset of breast cancer cells compared with untransformed MCF10A breast epithelial cells and in highly metastatic breast cancer cell lines derived from poorly metastatic MDA-MD-231 cells. In addition, patients with invasive ductal breast carcinoma show decreased TPM4 expression compared with patients with ductal breast carcinoma in situ, and low TPM4 expression is associated with poor prognosis...
May 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28403495/-diagnosis-and-therapeutic-management-in-kidney-ureter-and-bladder-trauma
#19
Karin Hirsch, Marco Heinz, Bernd Wullich
Trauma refers to the destruction of tissues or organs by external forces and it is the most common cause of mortality and morbidity in children (1, 2). Injuries of the genitourinary tract may be the result of blunt (falls, sport injuries, motor vehicle accidents and sexual abuse) or penetrating (stab wounds, gun shots, falling onto sharp objects) injuries. The genitourinary tract is significantly injured in 2.9% of paediatric trauma patients 4.In the paediatric population, the kidney is the most affected organ in the genitourinary tract (>60% of all genitourinary tract injuries) 4...
February 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28399089/-the-topical-problems-of-the-application-of-the-taser-electroshock-devices
#20
REVIEW
I V Kondratova, K Yu Kulinkovich
The objective of the present study was the analysis of publications in the foreign medical literature concerning the problems of safety, clinical diagnostics, pathological morphology, and treatment of the patients subjected to the impact by various models of the TASER electroshock devices. The materials for this article were borrowed from the available Internet resources and libraries. The methods of scientific analysis were employed to follow up the dynamics of publication and to determine the number of publications on the issues of interest...
2017: Sudebno-meditsinskaia Ekspertiza
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