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https://www.readbyqxmd.com/read/28705596/isolation-and-characterization-of-aerobic-anoxygenic-phototrophs-from-exposed-soils-from-the-s%C3%A3-r-rondane-mountains-east-antarctica
#1
Guillaume Tahon, Anne Willems
This study investigated the culturable aerobic phototrophic bacteria present in soil samples collected in the proximity of the Belgian Princess Elisabeth Station in the Sør Rondane Mountains, East Antarctica. Until recently, only oxygenic phototrophic bacteria (Cyanobacteria) were well known from Antarctic soils. However, more recent non-cultivation-based studies have demonstrated the presence of anoxygenic phototrophs and, particularly, aerobic anoxygenic phototrophic bacteria in these areas. Approximately 1000 isolates obtained after prolonged incubation under different growth conditions were studied and characterized by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry...
June 27, 2017: Systematic and Applied Microbiology
https://www.readbyqxmd.com/read/28701847/melioidosis-an-emerging-infection-with-fatal-outcomes
#2
Isabella Princess, R Ebenezer, Nagarajan Ramakrishnan, Arun Kumar Daniel, S Nandini, M A Thirunarayan
According to the Centers for Disease Control and Prevention, from being nonendemic for melioidosis, India has now become endemic for the disease since 2012. Until then, melioidosis cases were being reported sporadically from India. There have been isolated case reports from few states across the country for the past few years. Most of the times, Burkholderia pseudomallei may be misreported as Pseudomonas species, especially in resource-poor laboratories. Due to its varied clinical presentation, the specific clinical diagnosis can be difficult, thereby making laboratory diagnosis mandatory...
June 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28700296/princess-diana-and-reduced-traffic-deaths-in-france-and-the-united-states
#3
Donald A Redelmeier, Junaid A Bhatti
No abstract text is available yet for this article.
August 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28660153/vascular-diseases-of-the-spleen-a-review
#4
REVIEW
Pearl Princess D Uy, Denise Marie Francisco, Anshu Trivedi, Michael O'Loughlin, George Y Wu
Vascular diseases of the spleen are relatively uncommon in the clinical practice. However, the reported incidence has been progressively increasing, probably due to advances in the imaging modalities used to detect them. This disease condition often presents with non-specific clinical manifestations, but can be associated with significant morbidity and mortality. This review article aims to provide updated clinical information on the different vascular diseases of the splenic vasculature-splenic vein thrombosis, splenic vein aneurysm, splenic artery aneurysm, splenic arteriovenous fistula, and spontaneous splenorenal shunt-in order to aid clinicians in early diagnosis and management...
June 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/28647247/spatial-variability-and-possible-sources-of-acetate-and-formate-in-the-surface-snow-of-east-antarctica
#5
Gautami Samui, Runa Antony, Kanthanathan Mahalinganathan, Meloth Thamban
Spatial trends of acetate (Ac(-)) and formate (Fo(-)) were determined in surface snow samples along a coastal-inland transect (180km) in the ice cap region at Princess Elizabeth Land and along a coastal transect in the Amery Ice Shelf (130km), East Antarctica. Variations in both Ac(-) and Fo(-) seem to be unrelated to the acidity of snow. Ionic balance determined for the snow samples indicate the availability of HNO3 that could undergo photolysis to produce hydroxyl radical (OH), one of the major reactants involved in oxidation reactions with organic matter...
July 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28637367/parental-perceptions-of-hypothermia-treatment-for-neonatal-hypoxic-ischaemic-encephalopathy
#6
Balamurugan Thyagarajan, Vijay Baral, Ranjit Gunda, Denise Hart, Lisa Leppard, Brigitte Vollmer
AIMS: Hypothermia Treatment (HT) is now the standard of care for neonatal hypoxic-ischaemic encephalopathy (HIE). We conducted a survey to explore parental perceptions of HT as there is little information about this in the current literature. METHODS: Postal questionnaire survey including families (n=51) whose babies received HT at Princess Anne Hospital, Southampton, UK, with 23 questions covering communication, clinical management, follow-up, and care in general...
June 21, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28630177/integrated-genome-and-transcriptome-sequencing-identifies-a-noncoding-mutation-in-the-genome-replication-factor-donson-as-the-cause-of-microcephaly-micromelia-syndrome
#7
Gilad D Evrony, Dwight R Cordero, Jun Shen, Jennifer N Partlow, Timothy W Yu, Rachel E Rodin, R Sean Hill, Michael E Coulter, Anh-Thu N Lam, Divya Jayaraman, Dianne Gerrelli, Diana G Diaz, Chloe Santos, Victoria Morrison, Antonella Galli, Ulrich Tschulena, Stefan Wiemann, M Jocelyne Martel, Betty Spooner, Steven C Ryu, Princess C Elhosary, Jillian M Richardson, Danielle Tierney, Christopher A Robinson, Rajni Chibbar, Dana Diudea, Rebecca Folkerth, Sheldon Wiebe, A James Barkovich, Ganeshwaran H Mochida, James Irvine, Edmond G Lemire, Patricia Blakley, Christopher A Walsh
While next-generation sequencing has accelerated the discovery of human disease genes, progress has been largely limited to the "low hanging fruit" of mutations with obvious exonic coding or canonical splice site impact. In contrast, the lack of high-throughput, unbiased approaches for functional assessment of most noncoding variants has bottlenecked gene discovery. We report the integration of transcriptome sequencing (RNA-seq), which surveys all mRNAs to reveal functional impacts of variants at the transcription level, into the gene discovery framework for a unique human disease, microcephaly-micromelia syndrome (MMS)...
June 19, 2017: Genome Research
https://www.readbyqxmd.com/read/28622406/building-bridges-to-address-health-disparities-in-puerto-rico-the-salud-para-pi%C3%A3-ones-project
#8
Enid J García-Rivera, Princess Pacheco, Marielis Colón, Mary Helen Mays, Maricruz Rivera, Verónica Munet-Díaz, María Del R González, María Rodríguez, Rebecca Rodríguez, Astrid Morales
Over the past several decades, Puerto Ricans have faced increased health threats from chronic diseases, particularly diabetes and hypertension. The patient-provider relationship is the main platform for individual disease management, whereas the community, as an agent of change for the community's health status, has been limited in its support of individual health. Likewise, traditional research approaches within communities have placed academic researchers at the center of the process, considering their knowledge was of greater value than that of the community...
June 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28600529/synthesis-chemical-characterization-and-multiscale-biological-evaluation-of-a-dimeric-crgd-peptide-for-targeted-imaging-of-%C3%AE-v-%C3%AE-3-integrin-activity
#9
Jamila Hedhli, Andrzej Czerwinski, Matthew Schuelke, Agata Płoska, Paweł Sowinski, Lukas La Hood, Spencer B Mamer, John A Cole, Paulina Czaplewska, Maciej Banach, Iwona T Dobrucki, Leszek Kalinowski, Princess Imoukhuede, Lawrence W Dobrucki
Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β 3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β 3 activity (a radiolabeled version, (64)Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in vitro work). We investigated the performance of this probe at the receptor, cell, organ, and whole-body levels, including its use to detect diabetes associated impairment of ischemia-induced myocardial angiogenesis...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28589804/a-royal-turning-point
#10
Ian Hulatt
In disclosing the mental distress he experienced after the death of his mother Princess Diana, Prince Harry has joined a growing number of famous people who have felt enabled to make such issues public.
June 7, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28539305/deconstructing-cancer-patient-information-seeking-in-a-consumer-health-library-toward-developing-a-virtual-information-consult-for-cancer-patients-and-their-caregivers-a-qualitative-instrumental-case-study
#11
Janet Papadakos, Aileen Trang, Alaina B Cyr, Nazek Abdelmutti, Meredith E Giuliani, Michelle Snow, Tara McCurdie, Menaka Pulandiran, Sara Urowitz, David Wiljer
BACKGROUND: Cancer patients and their caregivers want information about their disease and are interested in finding health information online. Despite the abundance of cancer information online, it is often fragmented, its quality is highly variable, and it can be difficult to navigate without expert-level knowledge of the cancer system. The Patient & Family Library at the Princess Margaret Cancer Centre offers a broad collection of high-quality cancer health information and staff are available to help patrons refine their questions and explore information needs that they may not have considered...
May 24, 2017: JMIR Cancer
https://www.readbyqxmd.com/read/28504035/bleomycin-pulmonary-toxicity-does-not-adversely-affect-the-outcome-of-patients-with-hodgkin-lymphoma
#12
Haowei Linda Sun, Eshetu G Atenafu, Richard Tsang, Vishal Kukreti, Theodore K Marras, Michael Crump, John Kuruvilla
Bleomycin pulmonary toxicity (BPT) is a well-described complication of bleomycin-containing regimens. Previous data on risk factors and the impact of BPT on survival in Hodgkin lymphoma (HL) were conflicting. We reviewed 253 HL patients treated with adriamycin, bleomycin, vinblastine, dacarbazine (ABVD) at the Princess Margaret Hospital from 1999 to 2009 to examine the incidence and risk factors for BPT, and the effect of BPT on survival. BPT was defined by pulmonary symptoms, bilateral interstitial infiltrates on computed tomography, and the absence of infection...
May 15, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28488289/adversity-and-resilience-amongst-resettling-western-australian-paediatric-refugees
#13
Gemma Hanes, Lydia Sung, Raewyn Mutch, Sarah Cherian
AIM: Cumulative adverse childhood experiences have long-term consequences and may manifest within and influence health, educational and psychosocial domains. The Princess Margaret Hospital Refugee Health Service (RHS) undertakes multidisciplinary screening of refugee children <16 years, allowing standardised identification of negative childhood experiences. Addition of the extended Strengths and Difficulties Questionnaire (SDQ) in 2014 aimed to augment psychological assessment of this cohort...
May 10, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28482189/the-princess-and-the-pea-effect-influence-of-the-first-layer-on-polyelectrolyte-multilayer-assembly-and-properties
#14
Xuejian Lyu, Amy M Peterson
In many applications of polyelectrolyte multilayers (PEMs), a base polycation layer is adsorbed to promote adhesion of the PEM to the substrate. In this report, the effect of the first polyelectrolyte adsorbed in a PEM was investigated by assembling PEMs with first layer polycations of different chemistries and molecular weights. In this study, quartz crystal microbalance with dissipation monitoring (QCM-D) was used to monitor the PEM assembly process. First layer choice affects the total mass accumulation of the PEM as well as the stoichiometry of the PEM, although linear growth was observed in all cases...
April 29, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28480074/long-term-responders-to-palliative-chemotherapy-for-advanced-biliary-tract-cancer
#15
Mark K Doherty, Mairéad G McNamara, Priya Aneja, Emma McInerney, Stephanie Moignard, Anne M Horgan, Haiyan Jiang, Tony Panzarella, Raymond Jang, Neesha Dhani, David Hedley, Jennifer J Knox
BACKGROUND: Patients with advanced biliary tract cancer (BTC) are often treated with palliative chemotherapy (PC). Standard PC since 2010 is a cisplatin/gemcitabine doublet, with median overall survival (OS) of 11.7 months from the ABC-02 trial. Prior to this, our institutional standard was gemcitabine and fluoropyrimidine. The ABC-02 study used 8 cycles of PC as standard with treatment stopped even in the absence of disease progression, but some patients may benefit from continuing PC longer than 8 cycles...
April 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28458749/what-false-negative-rates-of-non-invasive-testing-are-active-surveillance-patients-and-uro-oncologists-willing-to-accept-in-order-to-avoid-prostate-biopsy
#16
Rashid Khalid Sayyid, Dharmendra Dingar, Katherine Fleshner, Taylor Thorburn, Joshua Diamond, Erik Yao, Karen Hersey, Karen Chadwick, Nathan Perlis, Laurence Klotz, Antonio Finelli, Robert Hamilton, Girish Kulkarni, Alexandre Zlotta, Neil Fleshner
INTRODUCTION: Repeat prostate biopsies in active surveillance patients are associated with significant complications. Novel imaging and blood/urine-based non-invasive tests are being developed to better predict disease grade and volume progression. We conducted a theoretical study to determine what test performance characteristics and costs would a non-invasive test(s) require in order for patients and their physicians to comfortably avoid biopsy. METHODS: Surveys were administered to two populations to determine an acceptable false-negative rate and cost for such test(s)...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28447222/feeding-strategies-in-pediatric-cancer-patients-with-gastrointestinal-mucositis-a-multicenter-prospective-observational-study-and-international-survey
#17
Nicoline S S Kuiken, Edmond H H M Rings, Marry M van den Heuvel-Eibrink, Marianne D van de Wetering, Wim J E Tissing
INTRODUCTION: Currently, there is no adequate prevention or treatment for both oral and gastrointestinal mucositis induced by chemotherapy and/or radiotherapy. Supportive care of symptoms plays a primary role during mucositis in the pediatric clinical setting. We aimed to get insight in the currently used feeding strategies in clinical practice in pediatric cancer patients with chemotherapy-induced mucositis. METHODS: A prospective observational study was performed to identify feeding strategies after chemotherapy courses causing mucositis in almost all patients at the University Medical Center Groningen (UMCG), the Academic Medical Center Amsterdam (AMC), and the Princess Maxima Center Utrecht (PMC)...
April 26, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28436498/integrative-meta-modeling-identifies-endocytic-vesicles-late-endosome-and-the-nucleus-as-the-cellular-compartments-primarily-directing-rtk-signaling
#18
Jared C Weddell, Princess I Imoukhuede
Recently, intracellular receptor signaling has been identified as a key component mediating cell responses for various receptor tyrosine kinases (RTKs). However, the extent each endocytic compartment (endocytic vesicle, early endosome, recycling endosome, late endosome, lysosome and nucleus) contributes to receptor signaling has not been quantified. Furthermore, our understanding of endocytosis and receptor signaling is complicated by cell- or receptor-specific endocytosis mechanisms. Therefore, towards understanding the differential endocytic compartment signaling roles, and identifying how to achieve signal transduction control for RTKs, we delineate how endocytosis regulates RTK signaling...
May 22, 2017: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/28420907/effectiveness-of-health-education-programme-level-of-knowledge-about-prevention-of-cervical-cancer-among-saudi-female-healthcare-students
#19
Ghadeer Khaled Al-Shaikh, Sadiqa Badar Syed, Amel Ahmed Fayed, Reem Ali Al-Shaikh, Eman Mohammed Al-Mussaed, Farida Habib Khan, Hala Nasser Elmorshedy
OBJECTIVE: To evaluate the effectiveness of health education programme on the knowledge of human papilloma virus among female medical students. METHODS: This quasi-experimental study was conducted in 2014 at the Princess Nourah bint Abulrahman University, Riyadh, Saudi Arabia, and comprised female medical students. An intervention programme was implemented in the form of lectures, videos, posters, etc. on human papillomavirus. SPSS 20 was used for data analysis...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28417030/knowledge-and-attitudes-towards-basic-life-support-among-health-students-at-a-saudi-women-s-university
#20
Maha A Al-Mohaissen
OBJECTIVES: Awareness of basic life support (BLS) is paramount to ensure the provision of essential life-saving medical care in emergency situations. This study aimed to measure knowledge of BLS and attitudes towards BLS training among female health students at a women's university in Saudi Arabia. METHODS: This prospective cross-sectional study took place between January and April 2016 at five health colleges of the Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia...
February 2017: Sultan Qaboos University Medical Journal
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