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Tong-Xin Yang, Bang-Hua Liao, Yun-Tian Chen, Hong Li, Qing He, Qin-Yu Liu, Kun-Jie Wang
We applied a newly introduced method, network meta-analysis, to re-evaluate the expulsion effect of drugs including tamsulosin, doxazosin, nifedipine, terazosin and rowatinex after extracorporeal shock wave lithotripsy (ESWL) as described in the literature. A systematic search was performed in Medline, Embase and Cochrane Library for articles published before March 2016. Twenty-six studies with 2775 patients were included. The primary outcome was the number of patients with successful stone expulsion. The data were subdivided into three groups according to duration of follow-up...
October 31, 2017: Scientific Reports
Tarek K Motawi, Samia A Ahmed, Manal A Hamed, Shohda A El-Maraghy, Wessam M Aziz
The study aimed to explore the prophylactic effect of melatonin, rowatinex; a naturally occurring renal drug, and its combination on diabetic nephropathy in type 2 diabetic rats. Diabetes was induced by intraperitoneal injection of a single dose of streptozotocin (50 mg/g body weight). Three days before diabetes induction, rats were daily treated with melatonin, rowatinex and their combination continuously for 8 weeks. Evaluation was done through measuring blood urea nitrogen (BUN), serum uric acid, serum creatinine, urine creatinine, creatinine clearance, nitric oxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH), total antioxidant capacity (TAC), kidney injury molecule-1 (KIM-1), heat shock protein-70 (HSP-70), caspase-3, transforming growth factor β1 (TGFβ1), DNA degradation by the comet assay and total protein contents...
November 1, 2017: Journal of Biomedical Research
Yu G Alyaev, V I Rudenko, A N Perekalina, I G Kraev, Zh Sh Inoyatov
Numerous metabolic abnormalities intrinsic to urolithiasis require drug therapy. At the same time, despite the constant expansion of synthetic drugs, plant-derived medications play a large role in the treatment and prevention of the disease. AIM: To evaluate the effect of a plant-derived preparation Rowatinex in patients with urolithiasis after extracorporeal shock wave lithotripsy (ESWL) and analyze the changes in blood and urine parameters in patients receiving the preparation. MATERIALS AND METHODS: Depending on the type of post-ESWL treatment, patients were divided into two groups...
April 2016: Urologii︠a︡
Andreas Skolarikos, Nikolaos Grivas, Panagiotis Kallidonis, Panagiotis Mourmouris, Thomas Rountos, Alexandros Fiamegos, Sotirios Stavrou, Chris Venetis
In this meta-analysis, we included randomized studies on medical expulsive therapy implemented following shock wave lithotripsy for renal and ureteral stones. Pooled results demonstrated the efficacy of α-blockers, nifedipine, Rowatinex, and Uriston in increasing stone clearance. In addition, the time to stone elimination, the intensity of pain, the formation of steinstrasse, and the need for auxiliary procedures were reduced mainly with α-blockers. Expulsion rate was not correlated with the type of α-blocker, the diameter, and the location of stone...
December 2015: Urology
İlknur Akyol-Salman, Deniz Leçe-Sertöz, Uğur Mumcu, Orhan Ateş, Orhan Baykal
Central serous chorioretinopathy (CSC) is an idiopathic disorder characterized by serous detachment of the neurosensory retina. This report describes a case of CSC associated with rowatinex usage.
December 2009: Eurasian Journal of Medicine
J Whan Lee, M Young Lee, I Young Seo
AIM: The aim of this study was to evaluate whether tamsulosin, an alpha-blocker, has an effect on decreasing spontaneous ureteral contractility with or without phenylephrine, an alpha-agonist. Additionally, nifedipine and a terpene mixture (Rowatinex®) were tested and compared with each other. METHODS: We obtained ureteral segments from freshly killed eight-week-old rabbits. Preparation was performed in an aerated Krebs buffer (95% oxygen and 5% carbon dioxide) at a constant temperature of 37 °C...
June 2015: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
V M Popkov, B I Bliumberg, O V Osnovin, T V Shatylko
Despite the high efficacy and safety of ESWL used to disintegrate stones in pyelocaliceal system and upper ureter, the issue of further reduction of the risk of complications of this procedure remains unresolved. The inclusion ofphytopreparations with anti-inflammatory and lithokinetic properties in the scheme of perioperative treatment is one of the ways for prevent complications of ESWL. The effect of the drug Rowatinex on the process of discharge of calculi fragments after ESWL is evaluated. The frequency and intensity of qualitative changes of urine after appointment this drug were assessed...
March 2014: Urologii︠a︡
Dai Hee Kim, Hyeok Jun Goh, Ho Won Lee, Kyu Shik Kim, Yong Tae Kim, Hong Sang Moon, Seung Wook Lee, Sung Yul Park
PURPOSE: Terpene combination (Rowatinex) is known to help with the expulsion of urinary stones. The aim of this study was to determine how Rowatinex affects the expulsion of remnant stones after shock wave lithotripsy (SWL). MATERIALS AND METHODS: Clinical data were collected retrospectively from 499 patients with a diagnosis of ureteral stones who underwent SWL from January 2009 to August 2012. Ureteral stones were diagnosed in all patients by kidney, ureter, and bladder x-ray and abdominal computed tomography (CT)...
January 2014: Korean Journal of Urology
Imre Romics, György Siller, Ralf Kohnen, Stelios Mavrogenis, József Varga, Endre Holman
OBJECTIVE: To investigate the safety and efficacy of a special terpene combination in the treatment of patients with urolithiasis after extracorporeal shockwave lithotripsy (ESWL). PATIENTS AND METHODS: 222 patients with clinically stable kidney or ureter stones of 0.3-2.0 cm undergoing complication-free ESWL were randomised to receive a special terpene combination (Rowatinex®; 3 × 2 capsules/day) or placebo. The study consisted of a 12-week active treatment phase and a 2-week follow-up phase...
2011: Urologia Internationalis
Mustafa Aldemir, Yusuf Emre Uçgül, Onder Kayıgil
PURPOSE: To compare the efficiency and spontaneous expulsion rates of tamsulosin and Rowatinex in patients with distal ureteral stones. METHODS: Between March and July 2009, 90 patients with distal ureteral stones <10 mm in size were included in the study. Patients were randomized in 3 groups: Group 1 (n = 31, those received 0.4 mg tamsulosin once daily), Group 2 (n = 30, those received 100 mg Rowatinex capsules 3 times a day), and Group 3 (n = 29, those received diclofenac 100 mg once daily)...
March 2011: International Urology and Nephrology
Y M Fazil Marickar, Abiya Salim, Adarsh Vijay
Most of the drugs administered to stone patients appear to be inappropriate and doing more harm than good to the patients. The objective of this paper is to identify the prevalence of blind chemotherapy among the stone patients and find out the real indication for the drugs administered. Patients who attended the stone clinic for the first time were interviewed to find out what drugs they had been taking before the attendance at the stone clinic. 350 patients consuming specific drugs relevant to stone formation at least for a period of 15 days were selected for a detailed assessment...
June 2010: Urological Research
Hooman Djaladat, Khatereh Mahouri, Fatemeh Khalifeh Shooshtary, Azadeh Ahmadieh
INTRODUCTION: our aim was to evaluate the effect of Rowatinex, an essential oil preparation of terpenic type, on kidney calculi clearance after extracorporeal shock wave lithotripsy (SWL). MATERIALS AND METHODS: A randomized controlled trial was performed at Hormozgan Hospital in Bandar Abbas, Iran, on 100 patients with 10-mm to 20-mm kidney calculi. They underwent SWL, and then, they were randomly assigned into 2 groups to receive either Rowatinex, 100 mg, 3 times per day, or placebo after SWL...
2009: Urology Journal
Choong Bum Lee, U-Syn Ha, Seung Ju Lee, Sae Woong Kim, Yong-Hyun Cho
To evaluate the efficacy of a terpene mixture (rowatinex) compared to ibuprofen, patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were randomly selected to either receive rowatinex 200 mg t.i.d. or ibuprofen 600 mg t.i.d. After a 6-week treatment, the decrease in the mean total NIH-CPSI score was significant in both groups from 21.4 to 15.3, (6.1 (p < 0.01) and from 21.2 to 16.8, (4.4 (p = 0.04) in the rowatinex and ibuprofen group, respectively. The rate of definite improvement as defined as 25% improvement in the total score was superior (p = 0...
February 2006: World Journal of Urology
C Pricop, C Novac, D Negru, Cristina Ilie, Adriana Pricop, Veronica Tănase
The majority of ureteral stones at presentation in hospital are located within the distal ureter. Knowing that only half of the stones 4 to 5.9 mm will pass spontaneously, we tried to see: if we can facilitate this elimination for the stones smaller than 8 mm by selectve alpha-blockers (alfuzosin and tamsulosin) which induce relaxation of the smooth muscle of uretrotrigonal area and if there is any difference between these two drugs, concerning efficiency and tolerance. The inclusion criteria for each group were: stone size between 4 and 8 mm--even patients with steinstrasse--and previous, at least 2 weeks of expulsion treatment with nonsteroidal antiinflammatory and antispasmodic agents and Rowatinex...
January 2004: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
No abstract text is available yet for this article.
July 1963: Nihon Hinyōkika Gakkai Zasshi. the Japanese Journal of Urology
No abstract text is available yet for this article.
June 1961: Magyar Sebészet
No abstract text is available yet for this article.
May 1959: Urologii︠a︡
Danuta Sybilska, Monika Asztemborska
Capillary gas chromatography was applied to explore the enantiomeric composition of some terpenoids in pharmaceuticals of natural origin. The drugs under investigation were produced in Germany (Rowachol, Rowatinex), Poland (Terpichol, Terpinex, Rub arom, Herbolen and Oleum Camphoratum), Slovenia (Uroterp, Mentoklar) and United Kingdom (Olbas oil, Vicks Vapo Rub). The model compounds tested were: menthone, isomenthone, menthol, fenchone, borneol and camphor. It has been found that depending on the manufacturer, pharmaceuticals possessing similar chemical composition may differ considerably in enantiomer composition...
December 31, 2002: Journal of Biochemical and Biophysical Methods
D Sybilska, J Kowalczyk, M Asztemborska, R J Ochocka, H Lamparczyk
A gas-liquid chromatographic system with alpha-cyclodextrin in formamide medium (coated on Chromosorb) was used for the separation of enantiomers of alpha-pinene, beta-pinene, limonene and camphene in medicines applied in the therapy of liver and kidney diseases. The drugs under investigation were produced in Poland (Terpichol and Terpinex), in Germany (Rowachol and Rowatinex) and in Slovenia (Uroterp). It was found that, depending on the manufacturer, medicines possessing similar chemical compositions differ considerably from one another regarding the content of enantiomers, mainly those of alpha-pinene...
April 8, 1994: Journal of Chromatography. A
D Greenwood, N Johnson, A Eley, R C Slack, G D Bell
No abstract text is available yet for this article.
December 1982: Journal of Antimicrobial Chemotherapy
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