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https://www.readbyqxmd.com/read/28736953/neutropenia-in-kidney-and-liver-transplant-recipients-risk-factors-and-outcomes
#1
Thomas A Mavrakanas, Marie-Andrée Fournier, Sarah Clairoux, Jacques-Alexandre Amiel, Marie-Eve Tremblay, Donald C Vinh, Christian Coursol, Daniel J G Thirion, Marcelo Cantarovich
No studies have directly compared the key characteristics and outcomes of kidney (KTx) and liver transplantation (LTx) recipients with neutropenia. In this single-center, retrospective, cohort study, we enrolled all adult patients who received a KTx or LTx between 2000 and 2011. Neutropenia was defined as two consecutive absolute neutrophil count (ANC) values <1500/mm(3) in patients without preexisting neutropenia. The first neutropenia episode occurring during the first-year posttransplantation was analyzed...
July 24, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28735254/how-should-i-treat-an-edwards-sapien-3-aortic-valve-embolisation-during-a-transaortic-transcatheter-aortic-valve-implantation
#2
Stephane Fournier, Pierre Monney, Christian Roguelov, Enrico Ferrari, Eric Eeckhout, Olivier Muller, Andras Durko, Nicolas M Van Mieghem, Arie Pieter Kappetein, Ronan Margey
No abstract text is available yet for this article.
July 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28733130/a-pilot-randomized-controlled-trial-on-the-effects-of-a-progressive-exercise-program-on-the-range-of-motion-and-upper-extremity-grip-strength-in-young-adults-with-breast-cancer
#3
Marize Ibrahim, Thierry Muanza, Nadia Smirnow, Warren Sateren, Beatrice Fournier, Petr Kavan, Michael Palumbo, Richard Dalfen, Mary-Ann Dalzell
BACKGROUND: The diagnosis of breast cancer in young women (aged 18-45 years) has been increasing. Women are commonly left coping with treatment-related disabilities of the upper limb that can persist for > 2 years postoperatively. PATIENTS AND METHODS: A total of 59 young breast cancer patients (29 in the intervention group and 30 in the control group) participated in a pilot prospective randomized controlled trial to determine whether a 12-week postradiation exercise program would improve long-term arm mobility, pain, and handgrip strength...
June 24, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28725440/description-of-beduinibacterium-massiliense-gen-nov-sp-nov-massilimaliae-massiliensis-gen-nov-sp-nov-provencibacterium-massiliense-gen-nov-sp-nov-and-oscilibacter-massiliensis-sp-nov-isolated-from-a-faecal-specimen-of-a-19-year-old-healthy-saudi-arabian-bedouin
#4
S I Traore, E I Azhar, M Yasir, F Bibi, P-E Fournier, A A Jiman-Fatani, J Delerce, F Cadoret, J-C Lagier, D Raoult
We report here the main characteristics of 'Beduinibacterium massiliense' strain Marseille-P3337(T) gen. nov., sp. nov., 'Massilimaliae massiliensis' Marseille-P2963(T) gen. nov., sp. nov., 'Provencibacterium massiliense' Marseille-P2780(T) gen. nov., sp. nov. and 'Oscilibacter massiliensis' Marseille-P2778(T) sp. nov., all isolated from the stool of a Bedouin from Saudi Arabia. We used a bacterial culturomics approach combined with taxonogenomics.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28723966/activated-carbon-a-useful-medium-to-bind-chlordecone-in-soil-and-limit-its-transfer-to-growing-goat-kids
#5
Sarah Yehya, Matthieu Delannoy, Agnès Fournier, Moomen Baroudi, Guido Rychen, Cyril Feidt
Chlordecone (Kepone) (CLD) is a highly persistent pesticide which was extensively used in the French West Indies; high levels of CLD can still currently be found in large agricultural areas. As CLD transfers from soil to animals mainly via involuntary ingestion, the consumption of foodstuffs derived from animals raised in contaminated areas may significantly contribute to exposure of humans to CLD. The present study was designed to test the efficacy of two different activated carbons (ACs) sources in limiting CLD transfer from soil to animal...
2017: PloS One
https://www.readbyqxmd.com/read/28723479/infectious-complications-of-circumcision-and-their-prevention
#6
REVIEW
Itzhak Brook
CONTEXT: A growing body of evidence supports the health benefits of circumcision, but the occurrence of infectious complications is of concern. OBJECTIVE: To review literature presenting past data and studies of infectious complications of circumcision and their prevention. EVIDENCE ACQUISITION: A literature search was conducted of the Cochrane Library, Embase, Turning Research into Practice, PubMed, and Medline databases from their inception through June 25, 2015...
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28721704/-overweight-and-obesity-in-the-canton-of-vaud-projections-for-2040
#7
Pierre Fournier, Lucie Favre, Michel Montavon, Marjorie Audard-Mariller, Michel Suter, Nicolas Demartines, François Pralong
The worldwide prevalence of obesity has more than doubled since 1980. This global figure needs to be addressed tackled at the local level to face our future challenges at the local level. We attempted to project the prevalence of obesity in the canton of Vaud in the next 25 years. Data from the Enquête suisse sur la santé, a survey conducted every five years since 1992 by the Swiss Federal Office of Public Health, were used. Using different mathematical assumptions, the rate of increase in the prevalence of obesity in Switzerland between 1992 and 2012 was calculated allowing a projection of future prevalences...
March 22, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28712002/mutations-in-gfpt1-related-congenital-myasthenic-syndromes-are-associated-with-synaptic-morphological-defects-and-underlie-a-tubular-aggregate-myopathy-with-synaptopathy
#8
Stéphanie Bauché, Geoffroy Vellieux, Damien Sternberg, Marie-Joséphine Fontenille, Elodie De Bruyckere, Claire-Sophie Davoine, Guy Brochier, Julien Messéant, Lucie Wolf, Michel Fardeau, Emmanuelle Lacène, Norma Romero, Jeanine Koenig, Emmanuel Fournier, Daniel Hantaï, Nathalie Streichenberger, Veronique Manel, Arnaud Lacour, Aleksandra Nadaj-Pakleza, Sylvie Sukno, Françoise Bouhour, Pascal Laforêt, Bertrand Fontaine, Laure Strochlic, Bruno Eymard, Frédéric Chevessier, Tanya Stojkovic, Sophie Nicole
Mutations in GFPT1 (glutamine-fructose-6-phosphate transaminase 1), a gene encoding an enzyme involved in glycosylation of ubiquitous proteins, cause a limb-girdle congenital myasthenic syndrome (LG-CMS) with tubular aggregates (TAs) characterized predominantly by affection of the proximal skeletal muscles and presence of highly organized and remodeled sarcoplasmic tubules in patients' muscle biopsies. We report here the first long-term clinical follow-up of 11 French individuals suffering from LG-CMS with TAs due to GFPT1 mutations, of which nine are new...
July 15, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28711476/treatment-in-early-psychosis-with-n-acetyl-cysteine-for-6months-improves-low-level-auditory-processing-pilot-study
#9
Chrysa Retsa, Jean-François Knebel, Eveline Geiser, Carina Ferrari, Raoul Jenni, Margot Fournier, Luis Alameda, Philipp S Baumann, Stephanie Clarke, Philippe Conus, Kim Q Do, Micah M Murray
Sensory impairments constitute core dysfunctions in schizophrenia. In the auditory modality, impaired mismatch negativity (MMN) has been observed in chronic schizophrenia and may reflect N-methyl-d-aspartate (NMDA) hypo-function, consistent with models of schizophrenia based on oxidative stress. Moreover, a recent study demonstrated deficits in the N100 component of the auditory evoked potential (AEP) in early psychosis patients. Previous work has shown that add-on administration of the glutathione precursor N-acetyl-cysteine (NAC) improves the MMN and clinical symptoms in chronic schizophrenia...
July 12, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28709981/relative-toxicity-for-indoor-semi-volatile-organic-compounds-based-on-neuronal-death
#10
Kevin Fournier, Emmanuel Baumont, Philippe Glorennec, Nathalie Bonvallot
BACKGROUND: Semi Volatile Organic Compounds (SVOCs) are contaminants commonly found in dwellings as a result of their use as plasticizers, flame retardants, or pesticides in building materials and consumer products. Many SVOCs are suspected of being neurotoxic, based on mammal experimentation (impairment of locomotor activity, spatial learning/memory or behavioral changes), raising the question of cumulative risk assessment. The aim of this work is to estimate the relative toxicity of such SVOCs, based on neuronal death...
July 11, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28708471/use-of-bisphosphonates-and-risk-of-breast-cancer-in-a-french-cohort-of-postmenopausal-women
#11
Agnès Fournier, Sylvie Mesrine, Amandine Gelot, Guy Fagherazzi, Laura Baglietto, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Nathalie Chabbert-Buffet
Purpose To assess whether bisphosphonate (BP) use is associated with decreased breast cancer incidence in a cohort of postmenopausal women. Methods The study population included 64,438 postmenopausal women participating in the French E3N (Etude Epidémiologique auprès de femmes de la Mutuelle Générale de l'Education Nationale) prospective cohort, with data self-reported in biennial questionnaires matched with data from a drug reimbursement database. Exposure to BPs and the use of other osteoporosis treatments during follow-up were determined using reimbursement data...
July 14, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28708033/neuropsychological-profile-and-social-cognition-in-congenital-central-hypoventilation-syndrome-cchs-correlation-with-neuroimaging-in-a-clinical-case
#12
Borja Esteso Orduña, Raquel Seijas Gómez, Elena García Esparza, Emily M Briceño, Javier Melero Llorente, María de la Concepción Fournier Del Castillo
INTRODUCTION: Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder due to paired-like homeobox gene (PHOX2B) mutations. CCHS patients suffer from dysregulation of the autonomic nervous system characterized by the absence of or extremely reduced response to hypercapnia and hypoxia, with neuropsychological deficits. The aim of this exploratory study is to describe the longitudinal neuropsychological profile and its correlations with magnetic resonance imaging (MRI) of a child with CCHS with a PHOX2B mutation...
July 14, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28706723/noncontiguous-finished-genome-sequences-and-description-of-bacillus-massiliglaciei-bacillus-mediterraneensis-bacillus-massilinigeriensis-bacillus-phocaeensis-and-bacillus-tuaregi-five-new-species-identified-by-culturomics
#13
F Cadoret, M T Alou, P Afouda, I S Traore, L Bréchard, C Michelle, F Di Pinto, C Andrieu, J Delerce, A Levasseur, P-E Fournier, D Raoult
Microbial culturomics, which investigates microbial diversity by combining diversified culture conditions, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rDNA identification, allowed to identify five new species within the Bacillus genus. Bacillus massiliglaciei strain Marseille-P2600(T), Bacillus mediterraneensis strain Marseille-P2384(T), Bacillus massilinigeriensis strain Marseille-P2366(T), Bacillus tuaregi strain Marseille-P2489(T) and Bacillus phocaeensis strain SIT16(T) are each the type strain of the corresponding bacterial species...
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28706722/-phoenicibacter-massiliensis-gen-nov-sp-nov-a-new-bacterium-isolated-from-the-human-gut-of-a-pygmy-woman
#14
M Bilen, F Cadoret, G Dubourg, P-E Fournier, Z Daoud, D Raoult
This study supports the main characteristics of the new genus and new species 'Phoenicibacter massiliensis' strain Marseille-P3241(T) (CSUR P3241), a new bacterium isolated from a stool sample of a healthy 47-year-old pygmy woman.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28705092/serum-allantoin-and-aminothiols-as-biomarkers-of-chronic-heart-failure
#15
Elizabeth Caussé, Pauline Fournier, Jérome Roncalli, Robert Salvayre, Michel Galinier
Background Oxidative stress (OS) represents the primary mediator of chronic heart failure (CHF) development and progression. It is well established that homocysteine is able to generate reactive oxygen species. Small amounts of allantoin in human serum result from free radical action on urate and may provide a stable marker for in vivo free radical activity. To investigate whether some easily measurable indexes such as antioxidants (uric acid, glutathione) and related molecules (allantoin, homocysteine and cysteine) can serve as OS biomarkers...
July 14, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28703976/l%C3%A2-irm-cardiovasculaire-entre-mythes-et-r%C3%A3-alit%C3%A3-s-quelle-utilit%C3%A3-pour-le-m%C3%A3-decin-praticien
#16
Monica Deac, Marie-Laure Duval, Dominique Fournier
No abstract text is available yet for this article.
January 25, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28702202/-khoudiadiopia-massiliensis-gen-nov-sp-nov-strain-marseille-p2746t-t-a%C3%A2-new-bacterial-genus-isolated-from-the-female-genital-tract
#17
A Diop, D Raoult, F Fenollar, P-E Fournier
We report the main characteristics of 'Khoudiadiopia massiliensis' gen. nov., sp. nov., strain Marseille-P2746(T) (= CSUR P2746), a new member of the Peptoniphilaceae family isolated from a vaginal swab of a patient suffering from bacterial vaginosis.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28702201/-marasmitruncus-massiliensis-gen-nov-sp-nov-clostridium-culturomicum-sp-nov-blautia-provencensis-sp-nov-bacillus-caccae-sp-nov-and-ornithinibacillus-massiliensis-sp-nov-isolated-from-stool-samples-of-undernourished-african-children
#18
T-P-T Pham, F Cadoret, M Tidjani Alou, S Brah, B Ali Diallo, A Diallo, C Sokhna, J Delerce, P-E Fournier, M Million, D Raoult
We report here the main characteristics of five new species, 'Marasmitruncus massiliensis' strain Marseille-P3646(T) (CSUR P3646), 'Clostridium culturomicum' strain Marseille-P3545(T) (CSUR P3545), 'Blautia provencensis' strain Marseille-P3502(T) (CSUR P3502), 'Bacillus caccae' strain Marseille-P3604(T) (CSUR P3604) and 'Ornithinibacillus massiliensis' strain Marseille-P3601(T) (CSUR P3601), which were isolated recently from undernourished children's stool samples from Niger using microbial culturomics.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28699877/isolation-and-characterization-of-kingella-negevensis-sp-nov-a-novel-kingella-species-detected-in-a-healthy-paediatric-population
#19
Nawal El Houmami, Sofiane Bakour, Janek Bzdrenga, Jaishiram Rathored, Hervé Seligmann, Catherine Robert, Nicholas Armstrong, Jacques Schrenzel, Didier Raoult, Pablo Yagupsky, Pierre-Edouard Fournier
We herein report the isolation and characterization of 21 Gram-stain-negative strains cultivated from the oropharynx of healthy children in Israel and Switzerland. Initially described as small colony variants of Kingella kingae, phenotypic analysis, biochemical analysis, phylogenetic analysis based on sequencing of the partial 16S rRNA gene and five housekeeping genes (abcZ, adk, G6PD, groEL and recA), and whole genome sequencing and comparison between members of the genera Kingella and Neisseria provided evidence for assigning them to the genus Kingella...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28698323/performance-of-highly-sensitive-cardiac-troponin-t-assay-to-detect-ischaemia-at-pet-ct-in-low-risk-patients-with-acute-coronary-syndrome-a-prospective-observational-study
#20
Beata Morawiec, Stephane Fournier, Maxime Tapponnier, John O Prior, Pierre Monney, Vincent Dunet, Nathalie Lauriers, Frederique Recordon, Catalina Trana, Juan-Fernando Iglesias, Damian Kawecki, Olivier Boulat, Daniel Bardy, Sabine Lamsidri, Eric Eeckhout, Olivier Hugli, Olivier Muller
BACKGROUND: Highly sensitive troponin T (hs-TnT) assay has improved clinical decision-making for patients admitted with chest pain. However, this assay's performance in detecting myocardial ischaemia in a lowrisk population has been poorly documented. PURPOSE: To assess hs-TnT assay's performance to detect myocardial ischaemia at positron emission tomography/CT (PET-CT) in low-risk patients admitted with chest pain. METHODS: Patients admitted for chest pain with a nonconclusive ECG and negative standard cardiac troponin T results at admission and after 6 hours were prospectively enrolled...
July 10, 2017: BMJ Open
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