keyword
MENU ▼
Read by QxMD icon Read
search

Cirrhotic cardiomyopathy

keyword
https://www.readbyqxmd.com/read/27843430/cirrhotic-cardiomyopathy-another-case-of-a-successful-approach-to-treatment-of-hepatorenal-syndrome
#1
Luis Otávio Mocarzel, Jessica Bicca, Luiza Jarske, Thamires Oliveira, Pedro Lanzieri, Ronaldo Gismondi, Mario Luiz Ribeiro
Hepatorenal syndrome (HRS) is defined as a failure of renal function, potentially reversible, in patients with liver cirrhosis and ascites. Recently, a component of cardiomyopathy associated with HRS was described, but the use of positive inotropic medicine as part of the treatment of the acute phase has not been extensively evaluated. We report a second case in our hospital of a patient with HRS type I without previous heart disease, with secondary hemodynamic decompensation due to liver disease, in which the abnormalities in systolic function by speckle-tracking echocardiography were observed and could be reversed by the use of inotropes...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27816131/anesthesia-patients-with-concomitant-cardiac-and-hepatic-dysfunction
#2
REVIEW
Julianne Ahdout, Michael Nurok
Anesthesia and surgery in patients with hepatic and cardiac dysfunction poses a challenge for anesthesiologists. It is imperative to optimize these patients perioperatively. Cirrhosis is associated with a wide range of cardiovascular abnormalities. Cirrhotic cardiomyopathy is characterized by blunted contractile responsiveness or systolic incompetence, and/or diastolic dysfunction. In liver disease, anesthetic drug distribution, metabolism, and elimination may be altered. Among patients with liver disease, propofol is a reasonable anesthetic choice and cisatracurium is the preferred neuromuscular blocker...
December 2016: Anesthesiology Clinics
https://www.readbyqxmd.com/read/27782364/survival-at-2%C3%A2-years-among-liver-cirrhotic-patients-is-influenced-by-left-atrial-volume-and-left-ventricular-mass
#3
Manuela Merli, Concetta Torromeo, Michela Giusto, Gianna Iacovone, Oliviero Riggio, Paolo E Puddu
BACKGROUND & AIMS: Cirrhotic cardiomyopathy (CC) may interact with the clinical course of cirrhosis and can be implicated in the development of several complications in advanced liver disease. The best and easiest parameters which should define a condition of reduced cardiac reserve in cirrhosis are still controversial. This study was aimed at selecting the cardiac parameters, derived by Doppler echocardiography, predictive of survival during follow-up. METHODS: This study included cirrhotic patients without cardiovascular or pulmonary diseases...
October 26, 2016: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/27727569/prevalence-of-cirrhotic-cardiomyopathy-in-patients-with-cirrhosis-of-liver
#4
S Sakthi Selva Kumar
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27686680/effect-of-ventriculo-arterial-coupling-on-transplant-outcomes-in-cirrhotics-analysis-of-pressure-volume-curve-relations
#5
Won-Jung Shin, Jun-Gol Song, In-Gu Jun, Young-Jin Moon, Hye-Mee Kwon, Kyeowoon Jung, Seon-Ok Kim, Gyu-Sam Hwang
BACKGROUND AND AIMS: Ventriculo-arterial coupling (VAC) reflects the interaction between ventricular performance and effective arterial load. Current criteria for cirrhotic cardiomyopathy focus only on cardiac function without addressing the effect of hyperdynamic, low-resistance circulation. We investigated alterations in VAC in cirrhotic patients and their associations with post-liver transplant all-cause mortality. METHODS: In this single institution cohort study, cirrhotic patients who underwent liver transplantation (LT) (n = 914) were retrospectively compared with healthy matched controls using noninvasively measured end-systolic ventricular elastance (Ees), arterial elastance (Ea), and VAC (Ea/Ees)...
September 26, 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27458853/galactin-3-and-brain-natriuretic-peptide-versus-conventional-echocardiography-in-the-early-detection-of-cirrhotic-cardiomyopathy
#6
Wael A Abbas, Soheir M Kasem Ahmed, Amal M Abdel Aal, Amal A Mahmoud, Mohamed O Abdelmalek, Mohamed A Mekky, Mohamed A A Abozaid, Ahmed K Ibrahim
BACKGROUND/AIMS: Cirrhotic cardiomyopathy (CCM) is defined as an abnormal heart structure and function in cirrhotic patients. CCM includes systolic and diastolic dysfunction, electrophysiological abnormalities, and structural changes, both microscopic and macroscopic. Currently, there is no one diagnostic test that can identify patients with CCM. Evaluation of the validity of galactin-3 and brain natriuretic peptide (BNP) as biomarkers in the early detection of CCM in comparison to conventional echocardiography...
July 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27353220/harm-reduction-a-systematic-review-on-effects-of-alcohol-reduction-on-physical-and-mental-symptoms
#7
Katrin Charlet, Andreas Heinz
Based on the knowledge that alcohol misuse causes a multitude of diseases and increased mortality, this systematic review examines whether a reduction of the individual alcohol consumption can contribute to a minimization of health risks within a harm reduction approach. In fact, the reviewed 63 studies indicate that interventions aiming at alcohol reduction (including total abstinence as one possible therapeutic aim) indeed resulted in or were associated with positive effects in harmful, hazardous or alcohol-dependent drinkers...
June 29, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27348483/ledipasvir-sofosbuvir-based-treatment-of-patients-with-chronic-genotype-1-hcv-infection-and-cirrhosis-results-from-two-phase-ii-studies
#8
Eric Lawitz, Fred Poordad, Robert H Hyland, Jing Wang, Lin Liu, Hadas Dvory-Sobol, Diana M Brainard, John G McHutchison, Julio A Gutierrez
BACKGROUND: Ledipasvir/sofosbuvir ± ribavirin administered for 12 weeks to patients with genotype 1 hepatitis C virus (HCV) infection and compensated cirrhosis is effective and well-tolerated. The Phase II TRILOGY-1 and TRILOGY-2 studies investigated whether ledipasvir/sofosbuvir plus the non-nucleotide NS5B inhibitor GS-9669 or the NS3/4A protease inhibitor vedroprevir could reduce treatment duration and/or eliminate the need for ribavirin in genotype 1 HCV-infected patients with compensated cirrhosis...
June 27, 2016: Antiviral Therapy
https://www.readbyqxmd.com/read/27292629/impact-and-persistence-of-cirrhotic-cardiomyopathy-after-liver-transplantation
#9
Abraham Sonny, Ahmed Ibrahim, Andres Schuster, Wael A Jaber, Jacek B Cywinski
Cirrhotic cardiomyopathy causes variable degree of systolic and diastolic dysfunction (DD) and conduction abnormalities. The primary aim of our study was to determine whether pre-transplant DD and prolonged corrected QT (QTc) predict a composite of mortality, graft failure, and major cardiovascular events after liver transplantation. We also evaluated the reversibility of cirrhotic cardiomyopathy after transplantation. Adult patients who underwent liver transplantation at our institution from January 2007 to March 2009 were included...
September 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27217700/contribution-of-mammalian-target-of-rapamycin-in-the-pathophysiology-of-cirrhotic-cardiomyopathy
#10
Seyed Soheil Saeedi Saravi, Mahmoud Ghazi-Khansari, Shahram Ejtemaei Mehr, Maliheh Nobakht, Seyyedeh Elaheh Mousavi, Ahmad Reza Dehpour
AIM: To explore the role of mammalian target of rapamycin (mTOR) in the pathogenesis of cirrhotic cardiomyopathy and the potential of rapamycin to improve this pathologic condition. METHODS: Male albino Wistar rats weighing 100-120 g were treated with tetrachloride carbon (CCl4) for 8 wk to induce cirrhosis. Subsequently, animals were administered rapamycin (2 mg/kg per day). The QTc intervals were calculated in a 5-min electrocardiogram. Then, the left ventricular papillary muscles were isolated to examine inotropic responsiveness to β-adrenergic stimulation using a standard organ bath equipped by Powerlab system...
May 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27075496/diastolic-dysfunction-in-cirrhosis
#11
Søren Møller, Signe Wiese, Hanne Halgreen, Jens D Hove
Development of esophageal varices, ascites, and hepatic nephropathy is among the major complications of cirrhosis. The presence of cirrhotic cardiomyopathy, which includes a left ventricular diastolic dysfunction (DD), seems to deteriorate the course of the disease and the prognosis. Increased stiffness of the cirrhotic heart may decrease the compliance and result in DD. The prevalence of DD in cirrhotic patients averages about 50 %. It can be evaluated by transmitral Doppler echocardiography, tissue Doppler echocardiography, and cardiac magnetic resonance imaging...
September 2016: Heart Failure Reviews
https://www.readbyqxmd.com/read/27011687/evaluation-of-cardiac-functions-of-cirrhotic-children-using-serum-brain-natriuretic-peptide-and-tissue-doppler-imaging
#12
Aya M Fattouh, Mortada H El-Shabrawi, Enas H Mahmoud, Wafaa O Ahmed
BACKGROUND: Cirrhotic cardiomyopathy (CCM) is described as the presence of cardiac dysfunction in cirrhotic patients. In children with chronic liver disease, CCM has been very rarely investigated. THE AIM OF THE STUDY: Is to evaluate the cardiac function of cirrhotic children to identify those with CCM. PATIENTS AND METHODS: Fifty-two cirrhotic patients and 53 age and sex matched controls were assessed using serum brain-type natriuretic peptide (BNP), conventional echocardiography, and tissue Doppler imaging...
January 2016: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/26973406/outcomes-of-abdominal-surgery-in-patients-with-liver-cirrhosis
#13
REVIEW
Juan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Antoni J Betbese, Joan A Roncal, Casimiro Javierre
Patients suffering from liver cirrhosis (LC) frequently require non-hepatic abdominal surgery, even before liver transplantation. LC is an important risk factor itself for surgery, due to the higher than average associated morbidity and mortality. This high surgical risk occurs because of the pathophysiology of liver disease itself and to the presence of contributing factors, such as coagulopathy, poor nutritional status, adaptive immune dysfunction, cirrhotic cardiomyopathy, and renal and pulmonary dysfunction, which all lead to poor outcomes...
March 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26915857/diastolic-dysfunction-in-liver-cirrhosis-prognostic-predictor-in-liver-transplantation
#14
F Carvalheiro, C Rodrigues, T Adrego, J Viana, H Vieira, C Seco, L Pereira, F Pinto, A Eufrásio, C Bento, E Furtado
BACKGROUND: Patients with liver cirrhosis may develop cirrhotic cardiomyopathy (CC), characterized by blunted contractile responsiveness to stress, diastolic dysfunction (DD), and electrophysiological abnormalities. It may adversely affect the long-term prognosis of these patients. METHODS: We conducted a retrospective analysis of patients undergoing liver transplantation (LT) for cirrhosis from January 2012 to June 2015. We analyzed demographic characteristics, the etiology of cirrhosis, Child-Pugh and Model for End-Stage Liver Disease (MELD) scores, the corrected QT (QTc) interval in the preoperative period, diastolic and systolic dysfunction, mortality and survival, and duration of mechanical ventilation and vasopressor support in the post-LT period...
January 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/26850503/cardiac-manifestations-in-alcoholic-liver-disease
#15
REVIEW
Sandra Milić, Davorka Lulić, Davor Štimac, Alen Ružić, Luka Zaputović
Alcoholic liver disease is the most prevalent cause of progressive liver disease in Europe. Alcoholic cirrhosis occurs in 8%-20% of cases of alcoholic liver disease. It has significant influence on cardiovascular system and haemodynamics through increased heart rate, cardiac output, decreased systemic vascular resistance, arterial pressure and plasma volume expansion. Cirrhotic cardiomyopathy is characterised by systolic and diastolic dysfunction and electrophysiological abnormalities, if no other underlying cardiac disease is present...
April 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/26839643/cirrhotic-cardiomyopathy-isn-t-stress-evaluation-always-required-for-the-diagnosis
#16
Mara Barbosa, Joana Guardado, Carla Marinho, Bruno Rosa, Isabel Quelhas, António Lourenço, José Cotter
AIM: To describe the proportion of patients with cirrhotic cardiomyopathy (CCM) evaluated by stress echocardiography and investigating its association with the severity of liver disease. METHODS: A cross-sectional study was conducted. Cirrhotic patients without risk factors for cardiovascular disease were included. Data regarding etiology and severity of liver disease (Child-Pugh score and model for end-stage liver disease), presence of ascites and gastroesophageal varices, pro-brain natriuretic peptide (pro-BNP) and corrected QT (QTc) interval were collected...
January 28, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/26556983/cirrhotic-cardiomyopathy
#17
REVIEW
Luis Ruiz-del-Árbol, Regina Serradilla
During the course of cirrhosis, there is a progressive deterioration of cardiac function manifested by the disappearance of the hyperdynamic circulation due to a failure in heart function with decreased cardiac output. This is due to a deterioration in inotropic and chronotropic function which takes place in parallel with a diastolic dysfunction and cardiac hypertrophy in the absence of other known cardiac disease. Other findings of this specific cardiomyopathy include impaired contractile responsiveness to stress stimuli and electrophysiological abnormalities with prolonged QT interval...
November 7, 2015: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26541640/cardiac-imaging-in-patients-with-chronic-liver-disease
#18
Signe Wiese, Jens D Hove, Søren Møller
Cirrhotic cardiomyopathy (CCM) is characterized by an impaired contractile response to stress, diastolic dysfunction and the presence of electrophysiological abnormalities, and it may be diagnosed at rest in some patients or demasked by physiological or pharmacological stress. CCM seems to be involved in the development of hepatic nephropathy and is associated with an impaired survival. In the field of cardiac imaging, CCM is not yet a well-characterized entity, hence various modalities of cardiac imaging have been applied...
November 5, 2015: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/26525531/diastolic-dysfunction-diagnosed-by-tissue-doppler-imaging-in-cirrhotic-patients-prevalence-and-its-possible-relationship-with-clinical-outcome
#19
Calogero Falletta, Daniela Filì, Cinzia Nugara, Gabriele Di Gesaro, Chiara Minà, Cesar Mario Hernandez Baravoglia, Giuseppe Romano, Cesare Scardulla, Fabio Tuzzolino, Giovanni Vizzini, Francesco Clemenza
BACKGROUND: Cirrhotic cardiomyopathy has been characterized by impaired contractile response to stress and/or altered diastolic relaxation, with electrophysiological abnormalities in the absence of known cardiac disease. However, the clinical significance of diastolic dysfunction (DDF) in cirrhotic patients has not been clarified. METHODS: We studied 84 cirrhotic patients with normal systolic function to evaluate the prevalence of DDF using tissue Doppler imaging, and to investigate the possible correlation of DDF with outcomes (hospitalization, death) and with the specific causes of death...
December 2015: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/26464674/increased-expression-of-78-kd-glucose-regulated-protein-promotes-cardiomyocyte-apoptosis-in-a-rat-model-of-liver-cirrhosis
#20
Lili Zhang, Huiying Zhang, Minli Lv, Jiantao Jia, Yimin Fan, Xiaoxia Tian, Xujiong Li, Baohong Li, Jingquan Ji, Limin Wang, Zhongfu Zhao, Dewu Han, Cheng Ji
AIMS: This study was to investigate the role and underlying mechanism of 78 kD glucose-regulated protein (GRP78) in cardiomyocyte apoptosis in a rat model of liver cirrhosis. METHODS: A rat model of liver cirrhosis was established with multiple pathogenic factors. A total of 42 male SD rats were randomly divided into the liver cirrhosis group and control group. Cardiac structure analysis was performed to assess alterations in cardiac structure. Cardiomyocytes apoptosis was detected by TdT-mediated dUTP nick end labeling method...
2015: International Journal of Clinical and Experimental Pathology
keyword
keyword
9145
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"