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https://www.readbyqxmd.com/read/28734105/effects-of-median-nerve-neural-mobilization-in-treating-cervicobrachial-pain-a-randomized-waiting-list-controlled-clinical-trial
#1
David Rodríguez-Sanz, Daniel López-López, Francisco Unda-Solano, Carlos Romero-Morales, Irene Sanz-Corbalán, Hector Beltrán-Alacreu, César Calvo-Lobo
BACKGROUND: There is a current lack of sufficiently high-quality randomized controlled clinical trials that measure the effectiveness of neural tissue mobilization techniques such as median nerve neural mobilization (MNNM) and their specific effects on cervicobrachial pain (CP). This study aim was to compare the effectiveness of MNNM in subjects with CP versus a waiting list control group (WLCG). METHODS: A single-blinded, parallel, randomized controlled clinical trial was performed (NCT02596815)...
July 22, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28727427/high-throughput-synthesis-and-structure-of-zeolite-zsm-43-with-two-directional-8-ring-channels
#2
Tom Willhammar, Jie Su, Yifeng Yun, Xiaodong Zou, Mobae Afeworki, Simon C Weston, Hilda B Vroman, William W Lonergan, Karl G Strohmaier
The aluminosilicate zeolite ZSM-43 (where ZSM = Zeolite Socony Mobil) was first synthesized more than 3 decades ago, but its chemical structure remained unsolved because of its poor crystallinity and small crystal size. Here we present optimization of the ZSM-43 synthesis using a high-throughput approach and subsequent structure determination by the combination of electron crystallographic methods and powder X-ray diffraction. The synthesis required the use of a combination of both inorganic (Cs(+) and K(+)) and organic (choline) structure-directing agents...
July 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28727323/indocyanine-green-near-infrared-lymphangiography-for-evaluation-of-effectiveness-of-edema-fluid-flow-under-therapeutic-compression
#3
Marzanna T Zaleska, Waldemar L Olszewski
The commonly used modalities for therapy of limb lymphedema are manual lymphatic drainage, manual devices moving edema fluid and intermittent pneumatic compression (IPC). What seems to be necessary for validation of the effect of the compression procedure is imaging of the mobilized moving edema fluid. Picture of edema fluid flow would allow the therapist to use force adjusted to the tissue volume and stiffness differing in various limb regions as well as identify sites of abundant accumulation of fluid requiring more compression...
July 20, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28724529/coactivators-and-general-transcription-factors-have-two-distinct-dynamic-populations-dependent-on%C3%A2-transcription
#4
Nikolaos Vosnakis, Marc Koch, Elisabeth Scheer, Pascal Kessler, Yves Mély, Pascal Didier, László Tora
SAGA and ATAC are two distinct chromatin modifying co-activator complexes with distinct enzymatic activities involved in RNA polymerase II (Pol II) transcription regulation. To investigate the mobility of co-activator complexes and general transcription factors in live-cell nuclei, we performed imaging experiments based on photobleaching. SAGA and ATAC, but also two general transcription factors (TFIID and TFIIB), were highly dynamic, exhibiting mainly transient associations with chromatin, contrary to Pol II, which formed more stable chromatin interactions...
July 19, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28722740/spectroscopic-imaging-studies-of-nanoscale-polarity-and-mass-transport-phenomena-in-self-assembled-organic-nanotubes
#5
Hao Xu, Shinobu Nagasaka, Naohiro Kameta, Mitsutoshi Masuda, Takashi Ito, Daniel A Higgins
Synthetic organic nanotubes self-assembled from bolaamphiphile surfactants are now being explored for use as drug delivery vehicles. In this work, several factors important to their implementation in drug delivery are explored. All experiments are performed with the nanotubes immersed in ethanol. First, Nile Red (NR) and a hydroxylated Nile Red derivative (NR-OH) are loaded into the nanotubes and spectroscopic fluorescence imaging methods are used to determine the apparent dielectric constant of their local environment...
July 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28720138/plantar-plate-pathology-is-associated-with-erosive-disease-in-the-painful-forefoot-of-patients-with-rheumatoid-arthritis
#6
Heidi J Siddle, Richard J Hodgson, Elizabeth M A Hensor, Andrew J Grainger, Anthony C Redmond, Richard J Wakefield, Philip S Helliwell
BACKGROUND: Disease-related foot pathology is recognised to have a significant impact on mobility and functional capacity in the majority of patients with rheumatoid arthritis (RA). The forefoot is widely affected and the metatarsophalangeal (MTP) joints are the most common site of symptoms. The plantar plates are the fibrocartilaginous distal attachments of the plantar fascia inserting into the five proximal phalanges. Together with the transverse metatarsal ligament they prevent splaying of the forefoot and subluxation of the MTP joints...
July 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28720119/calcified-amorphous-tumor-of-the-heart-with-mitral-annular-calcification-a-case-report
#7
Ryo Nakamaru, Hiroki Oe, Katsuomi Iwakura, Takafumi Masai, Kenshi Fujii
BACKGROUND: Calcified amorphous tumor of the heart is a rare, non-neoplastic cardiac mass characterized by nodular calcium in the background of amorphous degenerating fibrinous material. Clinical diagnosis of calcified amorphous tumor can be difficult, and current single imaging techniques do not specifically differentiate calcified amorphous tumor from other cardiac tumors such as calcified atrial myxoma, calcified thrombi, or vegetation. Complete surgical resection is the treatment of choice for both symptom improvement and prevention of embolization, as well as for pathological diagnosis...
July 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28718648/multi-imaging-of-cytokinin-and-abscisic-acid-on-the-roots-of-rice-oryza-sativa-using-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#8
Katsuhiro Shiono, Riho Hashizaki, Toyofumi Nakanishi, Tatsuko Sakai, Takushi Yamamoto, Koretsugu Ogata, Ken-Ichi Harada, Hajime Ohtani, Hajime Katano, Shu Taira
Plant hormones are important mobile endogenous signaling molecules that regulate responses to abiotic stress as well as plant growth and development. Visual information on more than one plant hormone from the same sample would be especially powerful, because it could enable rapid, intuitive interpretation. However, multi-imaging techniques for plant hormones have been unavailable. Here, we report the first multi-imaging of two plant hormones, one of cytokinin (i.e. trans-zeatin) and abscisic acid (ABA) by MALDI-TOF-MS imaging...
July 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28717721/evaluation-of-a-smartphone-based-training-strategy-among-health-care-workers-screening-for-cervical-cancer-in-northern-tanzania-the-kilimanjaro-method
#9
Karen E Yeates, Jessica Sleeth, Wilma Hopman, Ophira Ginsburg, Katharine Heus, Linda Andrews, Mary Rose Giattas, Safina Yuma, Godwin Macheku, Aziz Msuya, Olola Oneko
PURPOSE: Almost nine of 10 deaths resulting from cervical cancer occur in low-income countries. Visual inspection under acetic acid (VIA) is an evidence-based, cost-effective approach to cervical cancer screening (CCS), but challenges to effective implementation include health provider training costs, provider turnover, and skills retention. We hypothesized that a smartphone camera and use of cervical image transfer for real-time mentorship by experts located distantly across a closed user group through a commercially available smartphone application would be both feasible and effective in enhancing VIA skills among CCS providers in Tanzania...
December 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28716541/development-and-validation-of-an-accurate-gate-model-for-neuropet-scanner
#10
Peyman Sheikhzadeh, Hamid Sabet, Hossein Ghadiri, Parham Geramifar, Hojjat Mahani, Pardis Ghafarian, Mohammad Reza Ay
NeuroPET is a cylindrical full ring mobile PET/CT scanner for brain imaging that was developed by Photo Diagnostic Systems, Inc. The scanner has 7 modules, each with 3×4 detector blocks. The detectors have two layers of scintillator arrays with a half pixel pitch offset to realize two levels of depth of interaction. In this study, we evaluated the NeuroPET scanner modeled in the GATE simulation tool and analyzed the acquired data to better understand the contribution of inter-detector scattering (IDS). The results show that the average difference between simulated and measured data for a point-like source is 2...
July 14, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28716434/training-midwives-to-perform-basic-obstetric-point-of-care-ultrasound-in-rural-areas-using-a-tablet-platform-and-mobile-phone-transmission-technology-a-wfumb-coe-project
#11
Sudhir Vinayak, Joyce Sande, Harvey Nisenbaum, Christian Pállson Nolsøe
Point-of-care ultrasound (POCUS) has become a topical subject and can be applied in a variety of ways with differing outcomes. The cost of all diagnostic procedures including obstetric ultrasound examinations is a major factor in the developing world and POCUS is only useful if it can be equated to good outcomes at a lower cost than a routine obstetric examination. The aim of this study was to assess a number of processes including accuracy of images and reports generated by midwives, performance of a tablet-sized ultrasound scanner, training of midwives to complete ultrasounds, teleradiology solution transmissions of images via internet, review of images by a radiologist, communication between midwife and radiologist, use of this technique to identify high-risk patients and improvement of the education and teleradiology model components...
July 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28713255/the-impact-of-aerobic-exercise-on-fronto-parietal-network-connectivity-and-its-relation-to-mobility-an-exploratory-analysis-of-a-6-month-randomized-controlled-trial
#12
Chun L Hsu, John R Best, Shirley Wang, Michelle W Voss, Robin G Y Hsiung, Michelle Munkacsy, Winnie Cheung, Todd C Handy, Teresa Liu-Ambrose
Impaired mobility is a major concern for older adults and has significant consequences. While the widely accepted belief is that improved physical function underlies the effectiveness of targeted exercise training in improving mobility and reducing falls, recent evidence suggests cognitive and neural benefits gained through exercise may also play an important role in promoting mobility. However, the underlying neural mechanisms of this relationship are currently unclear. Thus, we hypothesize that 6 months of progressive aerobic exercise training would alter frontoparietal network (FPN) connectivity during a motor task among older adults with mild subcortical ischemic vascular cognitive impairment (SIVCI)-and exercise-induced changes in FPN connectivity would correlate with changes in mobility...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28712014/do-you-see-what-i-see-mobile-eye-tracker-contextual-analysis-and-inter-rater-reliability
#13
S Stuart, D Hunt, J Nell, A Godfrey, J M Hausdorff, L Rochester, L Alcock
Mobile eye-trackers are currently used during real-world tasks (e.g. gait) to monitor visual and cognitive processes, particularly in ageing and Parkinson's disease (PD). However, contextual analysis involving fixation locations during such tasks is rarely performed due to its complexity. This study adapted a validated algorithm and developed a classification method to semi-automate contextual analysis of mobile eye-tracking data. We further assessed inter-rater reliability of the proposed classification method...
July 15, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28711774/a-rotating-slit-collimator-based-gamma-radiation-mapper
#14
Jonas M C Nilsson, Robert R Finck, Christopher L Rääf
For situations with radioactive material out of control where it may be physically difficult or prohibited to access areas close to the source, measurements from distance may be the only way to assess the radiation environment. Using collimated detectors will provide means to locate the direction of the radiation from the source. To investigate the possibilities of mapping gamma emitting radioactive material in a closed non-enterable area, a tentative system for mapping radioactive materials from a distance was built...
July 13, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28710464/analysis-of-mitochondrial-organization-and-function-in-the-drosophila-blastoderm-embryo
#15
Sayali Chowdhary, Darshika Tomer, Dnyanesh Dubal, Devashree Sambre, Richa Rikhy
Mitochondria are inherited maternally as globular and immature organelles in metazoan embryos. We have used the Drosophila blastoderm embryo to characterize their morphology, distribution and functions in embryogenesis. We find that mitochondria are relatively small, dispersed and distinctly distributed along the apico-basal axis in proximity to microtubules by motor protein transport. Live imaging, photobleaching and photoactivation analyses of mitochondrially targeted GFP show that they are mobile in the apico-basal axis along microtubules and are immobile in the lateral plane thereby associating with one syncytial cell...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28708772/successful-laparoscopic-harvesting-of-omental-pedicle-flap-for-salvage-cerebral-revascularization-in-2-adults-with-moyamoya-disease-technique-and-lessons-learned
#16
Max Schumm, Kathleen Simon, Rapheal Sacho, Jon C Gould
Moyamoya is an idiopathic and progressive disease that leads to occlusion of intracranial arteries. When other methods of revascularization fail, omentum can be used as an indirect bypass to improve cerebral perfusion. Laparoscopic mobilization of a pedicled omental flap with subcutaneous tunneling to the brain has been described in small case series in children. We report our techniques and outcomes in 2 adults with Moyamoya to undergo such a procedure. An omental flap based on the right gastroepiploic artery was created and intraoperative fluorescence imaging using indocyanine green was used to assess the viability of the flap and to guide lengthening of the pedicle...
July 13, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28705994/wearable-brain-imaging-with-multi-modal-physiological-recording
#17
Gary E Strangman, Vladimir Ivkovic, Quan Zhang
The brain is a central component of cognitive and physical human performance. Measures including functional brain activation, cerebral perfusion, cerebral oxygenation, evoked electrical responses, and resting hemodynamic and electrical activity are all related to, or can predict health status or performance decrements. However, measuring brain physiology typically requires large, stationary machines that are not suitable for mobile or self-monitoring. Moreover, when individuals are ambulatory, systemic physiological fluctuations-e...
July 13, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28700598/tracing-social-interactions-in-pleistocene-north-america-via-3d-model-analysis-of-stone-tool-asymmetry
#18
Sabrina B Sholts, Joseph A M Gingerich, Stefan Schlager, Dennis J Stanford, Sebastian K T S Wärmländer
Stone tools, often the sole remnant of prehistoric hunter-gatherer behavior, are frequently used as evidence of ancient human mobility, resource use, and environmental adaptation. In North America, studies of morphological variation in projectile points have provided important insights into migration and interactions of human groups as early as 12-13 kya. Using new approaches to 3D imaging and morphometric analysis, we here quantify bifacial asymmetry among early North American projectile point styles to better understand changes in knapping technique and cultural transmission...
2017: PloS One
https://www.readbyqxmd.com/read/28700594/hierarchical-patterning-modes-orchestrate-hair-follicle-morphogenesis
#19
James D Glover, Kirsty L Wells, Franziska Matthäus, Kevin J Painter, William Ho, Jon Riddell, Jeanette A Johansson, Matthew J Ford, Colin A B Jahoda, Vaclav Klika, Richard L Mort, Denis J Headon
Two theories address the origin of repeating patterns, such as hair follicles, limb digits, and intestinal villi, during development. The Turing reaction-diffusion system posits that interacting diffusible signals produced by static cells first define a prepattern that then induces cell rearrangements to produce an anatomical structure. The second theory, that of mesenchymal self-organisation, proposes that mobile cells can form periodic patterns of cell aggregates directly, without reference to any prepattern...
July 2017: PLoS Biology
https://www.readbyqxmd.com/read/28699063/determination-of-collision-cross-sections-using-a-fourier-transform-electrostatic-linear-ion-trap-mass-spectrometer
#20
Eric T Dziekonski, Joshua T Johnson, Kenneth W Lee, Scott A McLuckey
Collision cross sections (CCSs) were determined from the frequency-domain linewidths in a Fourier transform electrostatic linear ion trap. With use of an ultrahigh-vacuum precision leak valve and nitrogen gas, transients were recorded as the background pressure in the mass analyzer chamber was varied between 4× 10(-8) and 7 × 10(-7) Torr. The energetic hard-sphere ion-neutral collision model, described by Xu and coworkers, was used to relate the recorded image charge to the CCS of the molecule. In lieu of our monoisotopically isolating the mass of interest, the known relative isotopic abundances were programmed into the Lorentzian fitting algorithm such that the linewidth was extracted from a sum of Lorentzians...
July 11, 2017: Journal of the American Society for Mass Spectrometry
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