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https://www.readbyqxmd.com/read/28097242/anterior-to-psoas-atp-fusion-of-the-lumbar-spine-evolution-of-a-technique-facilitated-by-changes-in-equipment
#1
Cristian Gragnaniello, Kevin Seex
BACKGROUND: Lateral interbody cages have been proven useful in spinal fusions. Spanning both lateral cortical rims while sparing the Anterior Longitudinal Ligament, the lateral interbody cages restore and maintain disc height while adding stability prior to supplemental fixation. The standard approach for their insertion is by a 90-degree lateral transpsoas method. This is relatively bloodless compared to other techniques although has its limitations, requiring neuro-monitoring and being, at times, very difficult at L4/5 due to iliac crest obstruction or an anterior plexus position...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28094955/using-diffusion-to-characterize-interfacial-heterogeneity
#2
Krystyna Kijewska, Gary J Blanchard
We report on the use of molecular diffusional motion over a range of length scales to characterize compositional heterogeneity in monolayer structures. This work focuses on the diffusional motion of perylene in two types of films supported on functionalized silica surfaces; single component (stearic acid) and two-component (hydrocarbon/fluorocarbon) films. Langmuir-Blodgett (LB) monolayers were deposited directly on silica or were bound to surface-modified silica by means of metal ion complexation. The LB films were characterized by their π-A isotherms and by Brewster angle microscopy (BAM) during formation and deposition...
January 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28094784/targeted-dna-sequencing-and-in-situ-mutation-analysis-using-mobile-phone-microscopy
#3
Malte Kühnemund, Qingshan Wei, Evangelia Darai, Yingjie Wang, Iván Hernández-Neuta, Zhao Yang, Derek Tseng, Annika Ahlford, Lucy Mathot, Tobias Sjöblom, Aydogan Ozcan, Mats Nilsson
Molecular diagnostics is typically outsourced to well-equipped centralized laboratories, often far from the patient. We developed molecular assays and portable optical imaging designs that permit on-site diagnostics with a cost-effective mobile-phone-based multimodal microscope. We demonstrate that targeted next-generation DNA sequencing reactions and in situ point mutation detection assays in preserved tumour samples can be imaged and analysed using mobile phone microscopy, achieving a new milestone for tele-medicine technologies...
January 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28093261/experimental-evaluation-of-a-new-morphological-approximation-of-the-articular-surfaces-of-the-ankle-joint
#4
Claudio Belvedere, Sorin Siegler, Andrea Ensini, Jason Toy, Paolo Caravaggi, Ramya Namani, Giulia Giannini, Stefano Durante, Alberto Leardini
The mechanical characteristics of the ankle such as its kinematics and load transfer properties are influenced by the geometry of the articulating surfaces. A recent, image-based study found that these surfaces can be approximated by a saddle-shaped, skewed, truncated cone with its apex oriented laterally. The goal of this study was to establish a reliable experimental technique to study the relationship between the geometry of the articular surfaces of the ankle and its mobility and stability characteristics and to use this technique to determine if morphological approximations of the ankle surfaces based on recent discoveries, produce close to normal behavior...
January 7, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28092549/learning-short-binary-codes-for-large-scale-image-retrieval
#5
Li Liu, Mengyang Yu, Ling Shao
Large-scale visual information retrieval has become an active research area in this big data era. Recently, hashing/ binary coding algorithms prove to be effective for scalable retrieval applications. Most existing hashing methods require relatively long binary codes (i.e., over hundreds of bits, sometimes even thousands of bits) to achieve reasonable retrieval accuracies. However, for some realistic and unique applications such as on wearable or mobile devices, only short binary codes can be used for efficient image retrieval due to the limitation of computational resources or bandwidth on these devices...
January 11, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28091721/influence-of-tooth-dimension-on-the-initial-mobility-based-on-plaster-casts-and-x-ray-images-a-numerical-study
#6
Martin Hartmann, Cornelius Dirk, Susanne Reimann, Ludger Keilig, Anna Konermann, Andreas Jäger, Christoph Bourauel
AIMS: The goal was to determine the influence of different geometric parameters of the tooth on the initial tooth mobility and the position of the center of resistance employing numerical models based on scaled X-ray images and plaster casts. METHODS: The dimensions of tooth 21 were measured in 21 patients, using radiographs and dental casts. Length and mesiodistal width of the tooth were obtained from the X-ray image and the orovestibular diameter from the plaster cast...
January 13, 2017: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/28091541/apelin-receptor-homodimer-oligomers-revealed-by-single-molecule-imaging-and-novel-g-protein-dependent-signaling
#7
Xin Cai, Bo Bai, Rumin Zhang, Chunmei Wang, Jing Chen
The apelin receptor (APJ) belongs to family A of the G protein-coupled receptors (GPCRs) and is a potential pharmacotherapeutic target for heart failure, hypertension, and other cardiovascular diseases. There is evidence APJ heterodimerizes with other GPCRs; however, the existence of APJ homodimers and oligomers remains to be investigated. Here, we measured APJ monomer-homodimer-oligomer interconversion by monitoring APJ dynamically on cells and compared their proportions, spatial arrangement, and mobility using total internal reflection fluorescence microscopy, resonance energy transfer, and proximity biotinylation...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28090375/autologous-bone-marrow-transplantation-in-multiple-sclerosis-biomarker-relevance-for-patient-recruitment-and-follow-up
#8
Ana C Londoño, Carlos A Mora
BACKGROUND: Despite the current availability of disease modifying therapies for the treatment of multiple sclerosis, there are still patients who suffer from severe neurological dysfunction in the relapsing-remitting or early progressive forms of the disease. For these patients autologous hematopoietic stem cell transplant offers an important therapeutic solution to prevent progression to irreversible disability. In spite of multiple studies in the last two decades, patient inclusion criteria, protocols for peripheral blood stem cell mobilization and bone marrow cell conditioning and methodology of follow up for autologous hematopoietic stem cell transplant in multiple sclerosis have not been strictly unified...
October 2016: Journal of Clinical & Cellular Immunology
https://www.readbyqxmd.com/read/28090044/acute-multiple-cerebral-infarction-in-a-patient-with-an-accessory-mitral-valve
#9
Ikuo Misumi, Asako Nagao, Katsuya Iwamoto, Tsuyoshi Honda, Masanobu Ishii, Hidetsugu Ueyama, Yasushi Maeda, Masatoshi Ishizaki, Ryoichi Kurisaki, Toshio Okazaki, Tetsuji Yamashita, Akiko Fujimoto, Yumi Honda
A 96-year-old woman developed hemiparesis 2 weeks after orthopedic surgery. Magnetic resonance imaging revealed multiple cerebral infarctions in the bilateral hemisphere. Transthoracic echocardiography revealed a mobile structure attached to the anterior mitral leaflet that protruded toward the left ventricular outflow tract. The structure was identified as an accessory mitral valve. Doppler echocardiography showed that there was no significant left ventricular outflow obstruction. This is a rare case of a silent accessory mitral valve that was detected after multiple cerebral infarctions...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28089745/dermoid-cysts-clinical-predictors-of-complex-lesions-and-surgical-complications
#10
Lucas T Lenci, Pari Shams, Erin M Shriver, Richard C Allen
PURPOSE: To evaluate the clinical characteristics and role of imaging in the evaluation of dermoid cysts and to determine predictors of cyst rupture during surgical excision of dermoid cysts. METHODS: In this single-center, consecutive, nonrandomized comparative case series, the records of consecutive patients with suspected dermoid cysts who underwent surgery between January 1, 2000, and December 31, 2014, were reviewed retrospectively for demographic information, clinical findings, preoperative imaging, surgical details, and pathology reports...
January 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28089570/use-of-augmented-reality-in-laparoscopic-gynecology-to-visualize-myomas
#11
Nicolas Bourdel, Toby Collins, Daniel Pizarro, Clement Debize, Anne-Sophie Grémeau, Adrien Bartoli, Michel Canis
OBJECTIVE: To report the use of augmented reality (AR) in gynecology. DESIGN: AR is a surgical guidance technology that enables important hidden surface structures to be visualized in endoscopic images. AR has been used for other organs, but never in gynecology and never with a very mobile organ like the uterus. We have developed a new AR approach specifically for uterine surgery and demonstrated its use for myomectomy. SETTING: Tertiary university hospital...
January 12, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28088226/use-of-an-intraoperative-navigation-system-for-retrieving-a-broken-dental-instrument-in-the-mandible-a-case-report
#12
Shintaro Sukegawa, Takahiro Kanno, Akane Shibata, Kenichi Matsumoto, Yuka Sukegawa-Takahashi, Kyosuke Sakaida, Yoshihiko Furuki
BACKGROUND: A fracture of root canal instruments, with a fractured piece protruding beyond the apex, is a troublesome incident during an endodontic treatment. Locating and retrieving them represents a challenge to maxillofacial surgeons because it is difficult to access due to the proximity between the foreign body and vital structures. Although safe and accurate for surgery, radiographs and electromagnetic devices do not provide a precise three-dimensional position. In contrast, computer-aided navigation provides a correlation between preoperatively collected data and intraoperatively encountered anatomy...
January 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28077665/spatial-cognition-in-a-virtual-reality-home-cage-extension-for-freely-moving-rodents
#13
Ursula Kaupert, Kay Thurley, Katja Frei, Francesco Bagorda, Alexej Schatz, Gilad Tocker, Sophia Rapoport, Dori Derdikman, York Winter
Virtual reality environments are part of a powerful tool set to investigate brain mechanisms of behavior in animals. For this, animals are mostly head-fixed or in a harness, and training for cognitively more complex VR paradigms is time consuming. A virtual reality apparatus allowing free animal movement and 24/7 operator-independent training of tasks would enable many new applications. Key prospective usages include brain imaging in behaving animals carrying a miniaturized mobile device such as a fluorescence microscope, or an optetrode...
January 11, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28072470/sonographic-dynamic-description-of-the-laryngeal-tract-definition-of-quantitative-measures-to-characterize-vocal-fold-motion-and-estimation-of-their-normal-values
#14
Héloïse Bergeret-Cassagne, Diane S Lazard, Muriel Lefort, Siham Hachi, Laurence Leenhardt, Fabrice Menegaux, Gilles Russ, Christophe Trésallet, Frédérique Frouin
Vocal fold motion was analyzed during free breathing using two-dimensional dynamic ultrasound imaging. Two cadavers were first analyzed to define easily identifiable landmarks. Motion of the laryngeal tract was then analyzed in an axial plane. Left and right arytenoids and thyroid cartilage were defined on images corresponding to abduction and adduction of the laryngeal tract. Associated area measurements were established for 50 healthy subjects. All area indices were significantly larger during abduction than adduction...
January 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28070456/a-simple-rat-model-of-mild-traumatic-brain-injury-a-device-to-reproduce-anatomical-and-neurological-changes-of-mild-traumatic-brain-injury
#15
Ho Jeong Kim, Soo Jeong Han
Mild traumatic brain injury typically involves temporary impairment of neurological function. Previous studies used water pressure or rotational injury for designing the device to make a rat a mild traumatic brain injury model. The objective of this study was to make a simple model of causing mild traumatic brain injury in rats. The device consisted of a free-fall impactor that was targeted onto the rat skull. The weight (175 g) was freely dropped 30 cm to rat's skull bregma. We installed a safety device made of acrylic panel...
2017: PeerJ
https://www.readbyqxmd.com/read/28069951/calsequestrin-depolymerizes-when-calcium-is-depleted-in-the-sarcoplasmic-reticulum-of-working-muscle
#16
Carlo Manno, Lourdes C Figueroa, Dirk Gillespie, Robert Fitts, ChulHee Kang, Clara Franzini-Armstrong, Eduardo Rios
Calsequestrin, the only known protein with cyclical storage and supply of calcium as main role, is proposed to have other functions, which remain unproven. Voluntary movement and the heart beat require this calcium flow to be massive and fast. How does calsequestrin do it? To bind large amounts of calcium in vitro, calsequestrin must polymerize and then depolymerize to release it. Does this rule apply inside the sarcoplasmic reticulum (SR) of a working cell? We answered using fluorescently tagged calsequestrin expressed in muscles of mice...
January 9, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28066886/precise-observation-of-c-elegans-dynamic-behaviours-under-controlled-thermal-stimulus-using-a-mobile-phone-based-microscope
#17
T Yoon, D-M Shin, S Kim, S Lee, T G Lee, K Kim
We investigated the temperature-dependent locomotion of Caenorhabditis elegans by using the mobile phone-based microscope. We developed the customized imaging system with mini incubator and smartphone to effectively control the thermal stimulation for precisely observing the temperature-dependent locomotory behaviours of C. elegans. Using the mobile phone-based microscope, we successfully followed the long-term progress of specimens of C. elegans in real time as they hatched and explored their temperature-dependent locomotory behaviour...
January 9, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28064140/reduced-radiation-dose-and-improved-image-quality-using-a-mini-mobile-digital-imaging-system-in-a-neonatal-intensive-care-unit
#18
Tae-Hoon Kim, Jong-Hyun Ryu, Chang-Won Jeong, Hong Young Jun, Dong-Woon Heo, Seung Hyun Lee, Yeon Kyun Oh, Mi-Jung Lee, Kwon-Ha Yoon
This study was aimed to assess the radiation dose and image quality of a mini-mobile digital imaging (mini-DI) system for neonatal chest radiography and compared to conventional digital radiography (DR). A total of 64 neonates were examined and anatomical landmarks were assessed. The entrance surface dose of mini DI and conventional DR was 26.64±0.15 μGy and 49.11±1.46 μGy, respectively (p<0.001). The mean SNR values for mini-DI and DR were 233.2±5.1 and 31.6±1.2, and 10% MTF values were 131 and 161μm...
December 6, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/28063264/preimplantation-3d-ultrasound-current-uses-and-challenges
#19
Sushila Arya, Sanja Kupesic Plavsic
The preimplantation ultrasound (US) refers to targeted imaging of the uterus and adnexa prior to assisted reproductive techniques (ART) to optimize the infertility treatment outcomes. After a thorough evidence based literature review, we propose the use of transvaginal three-dimensional (3D) US during the early follicular phase. A systematic approach for 3D US examination consists of a detailed examination of the uterine shape, size and contour, evaluation of the endometrial thickness, volume, pattern and vascularity, and assessment of the junctional zone regularity, echogenicity and thickness...
January 7, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28060865/agent-based-modeling-of-mitochondria-links-sub-cellular-dynamics-to-cellular-homeostasis-and-heterogeneity
#20
Giovanni Dalmasso, Paula Andrea Marin Zapata, Nathan Ryan Brady, Anne Hamacher-Brady
Mitochondria are semi-autonomous organelles that supply energy for cellular biochemistry through oxidative phosphorylation. Within a cell, hundreds of mobile mitochondria undergo fusion and fission events to form a dynamic network. These morphological and mobility dynamics are essential for maintaining mitochondrial functional homeostasis, and alterations both impact and reflect cellular stress states. Mitochondrial homeostasis is further dependent on production (biogenesis) and the removal of damaged mitochondria by selective autophagy (mitophagy)...
2017: PloS One
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