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https://www.readbyqxmd.com/read/27140227/validation-of-a-self-administered-audiometry-application-an-equivalence-study
#1
Jonathon P Whitton, Kenneth E Hancock, Jeffrey M Shannon, Daniel B Polley
OBJECTIVES/HYPOTHESIS: To compare hearing measurements made at home using self-administered audiometric software against audiological tests performed on the same subjects in a clinical setting STUDY DESIGN: Prospective, crossover equivalence study METHODS: In experiment 1, adults with varying degrees of hearing loss (N = 19) performed air-conduction audiometry, frequency discrimination, and speech recognition in noise testing twice at home with an automated tablet application and twice in sound-treated clinical booths with an audiologist...
October 2016: Laryngoscope
https://www.readbyqxmd.com/read/27118819/tablet-audiometry-in-canada-s-north-a-portable-and-efficient-method-for-hearing-screening
#2
Ryan Rourke, David Chan Chun Kong, Matthew Bromwich
BACKGROUND: Access to hearing health care is limited in many parts of the world, creating a lack of prompt diagnosis, which further complicates treatment. The use of portable audiometry for hearing loss testing can improve access to diagnostics in marginalized populations. Our study objectives were twofold: (1) to determine the prevalence of hearing loss in children aged 4 to 11 years in Iqaluit, Nunavut, and (2) to test and demonstrate the use of our tablet audiometer as a portable hearing-testing device in a remote location...
September 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26183518/accuracy-of-a-tablet-audiometer-for-measuring-behavioral-hearing-thresholds-in-a-clinical-population
#3
Gregory P Thompson, Douglas P Sladen, Becky J Hughes Borst, Owen L Still
OBJECTIVE: To examine the validity of a tablet computer-based audiometer for measuring hearing thresholds in a moderately noisy environment. STUDY DESIGN: A prospective single-cohort repeated measures study. SETTING: Tertiary care institution providing hearing health care to a diverse population. SUBJECTS AND METHODS: Subjects included 49 participants (44 adults, 5 children) with all degrees of hearing sensitivity. Potential participants were excluded if they were <4 years old or had cognitive deficits or ear drainage...
November 2015: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26055197/self-administered-hearing-loss-screening-using-an-interactive-tablet-play-audiometer-with-ear-bud-headphones
#4
Jeffrey C Yeung, Sophie Heley, Yves Beauregard, Sandra Champagne, Matthew A Bromwich
BACKGROUND AND OBJECTIVE: The timely diagnosis and treatment of acquired hearing loss in the pediatric population has significant implications for a child's development. Audiological assessment in children, however, carries both technological and logistical challenges. Typically, specialized methods (such as play audiometry) are required to maintain the child's attention and can be resource intensive. These challenges were previously addressed by a novel, calibrated, interactive play audiometer for Apple(®) iOS(®) called "ShoeBOX Audiometry"...
August 2015: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/25363170/comparison-of-local-and-systemic-ciprofloxacin-ototoxicity-in-the-treatment-of-chronic-media-otitis
#5
RANDOMIZED CONTROLLED TRIAL
R Samarei
INTRODUCTION: Chronic media otitis is a common cause of reference to ear, nose and throat clinics and the treatment is one of the health problems among ENT specialists. Ciprofloxacin drop that is of fluoroquinolone drug class due to good treatment effect is now widely used in the treatment of chronic media otitis. Due to the widespread use, it seems proper research on the human population has not been taken to ensure its non-toxicity in the inner ear, therefore comparison of local ciprofloxacin ototoxicity with systemic in chronic media otitis is investigated in this study...
2014: Global Journal of Health Science
https://www.readbyqxmd.com/read/23663317/the-new-age-of-play-audiometry-prospective-validation-testing-of-an-ipad-based-play-audiometer
#6
RANDOMIZED CONTROLLED TRIAL
Jeffrey Yeung, Hedyeh Javidnia, Sophie Heley, Yves Beauregard, Sandra Champagne, Matthew Bromwich
OBJECTIVE: The timely diagnosis of hearing loss in the pediatric population has significant implications for a child's development. However, audiological evaluation in this population poses unique challenges due to difficulties with patient cooperation. Though specialized adaptations exist (such as conditioned play audiometry), these methods can be time consuming and costly. The objective of this study was to validate an iPad-based play audiometer that addresses the shortcomings of existing audiometry...
2013: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/23250528/-the-role-of-neurotropic-therapy-in-the-treatment-of-acute-sensorineural-impairment-of-hearing-following-a-viral-infection
#7
A G Atanesian, S Ia Kosiakov
The objective of the study. To estimate the efficacy of consecutive prescription of combined neurotropic therapy in addition to conventional treatment modalities for the patients presenting with acute sensorineural impairment of hearing. The results of analysis of the examination and treatment of 58 patients presenting with acute sensorineural impairment of hearing following a viral infection are presented. The patients of the study group (group 1) received the treatment according to the following scheme: intramuscular injections of milgamma at a dose of 2 ml for 10 days followed by the intake of milgamma tablets thrice daily during 20 days...
2012: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/23001433/ondansetron-in-patients-with-tinnitus-randomized-double-blind-placebo-controlled-study
#8
RANDOMIZED CONTROLLED TRIAL
Shervin Taslimi, Hamed Vahidi, Ali Pourvaziri, Amirhossein Modabbernia, Arezoo Yeke Fallah, Nasrin Yazdani, Negin Taslimi, Mostafa Hosseini, Masoud Motesadi Zarandi
The aim of this study was to assess the effect of ondansetron on symptoms of patients with subjective tinnitus accompanied by sensorineural hearing loss or normal hearing. Sixty patients with a chief complaint of tinnitus (with duration of more than 3 months) were equally randomized to ondansetron or placebo for 4 weeks. The dose of ondansetron was gradually increased from 4 mg/day (one tablet) to 16 mg/day (4 tablets) during 12 days and then continued up to 4 weeks. The exact number of tablets was prescribed in the placebo group...
May 2013: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/20690865/effect-of-tibolone-on-audiologic-functions-in-menopausal-women
#9
RANDOMIZED CONTROLLED TRIAL
N Köşüş, A Köşüş, N Ö Turhan, H Kurtaran
OBJECTIVE: The aim of this study was to examine the effect of tibolone on hearing function in postmenopausal women. METHODS: This prospective study involved 60 postmenopausal women. Participants were randomly divided into two groups. The tibolone group was assigned to receive a tibolone tablet daily (n = 30). The other 30 cases who had not received any kind of hormone therapy were taken as the control group. The hearing levels of both ears in all women were measured by audiometry before initiation of tibolone therapy and 6 months after therapy...
April 2011: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/19222841/evaluation-of-vardenafil-for-the-treatment-of-subjective-tinnitus-a-controlled-pilot-study
#10
RANDOMIZED CONTROLLED TRIAL
Birgit Mazurek, Heidemarie Haupt, Agnieszka J Szczepek, Jörg Sandmann, Johann Gross, Burghard F Klapp, Holger Kiesewetter, Ulrich Kalus, Timo Stöver, Philipp P Caffier
BACKGROUND: Vardenafil (Levitra(R)) represents a potent and highly selective phosphodiesterase type 5 (PDE5) inhibitor, which is established for treatment of various diseases. There are several unpublished reports from patients stating that vardenafil has a considerable therapeutic effect on their concomitant tinnitus. This pilot study was conducted to specifically assess the effect of vardenafil in patients with chronic tinnitus. METHODS: This trial was based on a prospective, randomized, double-blind, placebo-controlled, parallel group design...
2009: Journal of Negative Results in Biomedicine
https://www.readbyqxmd.com/read/17049780/intratympanic-injection-of-dexamethasone-as-an-alternative-treatment-of-steroid-dependent-sensorineural-hearing-loss-associated-with-aortitis-syndrome
#11
Toshihisa Murofushi, Haruka Nakahara, Aki Sakata, Masaki Matsuzaki
We report a 44-year-old Japanese woman who presented with fluctuating hearing loss. She suffered from aortitis syndrome (AS) since she was 30-year-old and took daily tablets of prednisolone (10mg). Pure tone audiometry showed bilateral high-tone sensorineural hearing loss. Although her hearing recovered with higher doses of steroids, she was concerned about the systemic side effects of frequent administration of high doses of steroids. Thus, she underwent intratympanic injection of dexamethasone at the time of worsening of hearing...
June 2007: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/12053674/-results-of-combined-treatment-for-vestibular-receptor-impairment-with-physical-therapy-and-ginkgo-biloba-extract-egb-761
#12
Krystyna Orendorz-Fraczkowska, Lucyna Pośpiech, Wojciech Gawron
UNLABELLED: Vestibular receptor impairment causes symptoms called vestibular organ peripheral lesion syndrome. Subjective and objective symptoms of vestibular lesion diminish gradually in the process of vestibular compensation. Stimulating a patient to action is a basic factor that influences on the compensation process. The aim of our studies was an evaluation of treatment results in patients with vertigo of peripheral origin with the use of gingko biloba extract together with kinezytherapy...
2002: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/11771024/efficacy-of-amitriptyline-in-the-treatment-of-subjective-tinnitus
#13
RANDOMIZED CONTROLLED TRIAL
N Bayar, B Böke, E Turan, E Belgin
We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus. The study group consisted of 37 adult patients admitted to the Ear, Nose, and Throat and Audiology Department of Hacettepe University. The amitriptyline group consisted of 20 patients and the placebo group consisted of 17 patients. All of the patients were evaluated using a questionnaire, audiologic evaluation, high-frequency audiometry, impedancemetric tests, auditory brainstem response, tinnitus frequency, and loudness matching assessed by audiometric methods at the beginning and end of the study...
October 2001: Journal of Otolaryngology
https://www.readbyqxmd.com/read/11769996/steroids-carbogen-or-placebo-for-sudden-hearing-loss-a-prospective-double-blind-study
#14
RANDOMIZED CONTROLLED TRIAL
U Cinamon, E Bendet, J Kronenberg
There is no consensus regarding treatment modalities for idiopathic sudden sensorineural hearing loss (SNHL). In order to evaluate the effectiveness of steroid or carbogen inhalation therapies, a prospective double-blind placebo controlled study was designed. All 41 patients enrolled in the study had unilateral SNHL with no prior history of SNHL, otological pathological history or otoscopic findings. Patients were assigned to four treatment groups: prednisone tablets, placebo tablets, carbogen inhalation or room air inhalation...
November 2001: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/8509313/effects-of-aspirin-on-human-auditory-filters
#15
R P Carlyon, M Butt
Auditory filter shapes were measured in eight male volunteers with normal hearing, using a notched-noise forward-masking paradigm and a signal frequency of 4 kHz. The measurements were made under three conditions: after listeners had taken eight doses of three 320 mg aspirin tablets every six hours; after an identical schedule of placebo ingestion; and one week after testing in the first two conditions had been completed. Half of the listeners did the placebo condition first, and half did the aspirin condition first...
April 1993: Hearing Research
https://www.readbyqxmd.com/read/8333884/-results-of-a-prospective-open-study-of-therapy-of-sudden-deafness-with-flunarizine
#16
R Meier, K Tschopp, M Podvinec, R Grossenbacher, D Ermanni, R Probst
The treatment effect of the lipophilic calcium antagonist flunarizine on the recovery of sudden hearing loss was evaluated in a prospective phase-II study. Thirty-seven patients presenting with recent and sudden onset of unilateral sensorineural hearing loss were treated with 50 mg flunarizine intravenously for the first two days followed by 10 mg flunarizine orally for four weeks. Pure-tone audiometry was done before the beginning of the treatment and after one and four weeks. The absolute and relative hearing gains after one and four weeks were compared to those of 67 similar patients previously treated with saline infusions and placebo tablets in the same institutions during a double blind study (Probst et al...
June 1993: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/7458751/-therapeutic-results-in-acute-acoustic-trauma-author-s-transl
#17
H Eibach, U Börger
The prime aim of this study is to investigate the influence of therapeutic measures in acute acoustic trauma (AAT). In a controlled clinical trial 209 patients (Table 1) was observed, starting within 2 days after the traumatic event. Various chemical agents, considered to have some influence on microciculation and metabolism of the inner ear, were administered as shown in Table 2. The control group was treated with NaCl infusions and glucose tablets. Statistical analysis of the audiometric data was performed in two different ways (Fig...
1980: Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/6849784/disposition-of-chloroquine-in-man-after-single-intravenous-and-oral-doses
#18
RANDOMIZED CONTROLLED TRIAL
L L Gustafsson, O Walker, G Alván, B Beermann, F Estevez, L Gleisner, B Lindström, F Sjöqvist
1 Chloroquine was given in 300 mg single doses as an i.v. infusion, an oral solution and as tablets at intervals of at least 56 days to 11 healthy volunteers. Concentrations of chloroquine and its metabolite desethylchloroquine were measured in plasma, erythrocytes and urine using h.p.l.c. 2 Chloroquine was detectable in all plasma samples up to 23 days and occasionally up to 52 days after dosage. Urinary concentrations were monitored up to 119 days. The disposition pattern was multiexponential reflecting extensive tissue binding of the drug...
April 1983: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/3744912/-treatment-of-sudden-deafness-with-xantinolnicotinate-complamin-in-increasing-dosage
#19
A Halevy, G Strohm, U Wieczorek
Twenty-nine patients affected by typical unilateral sudden hearing loss were treated with Xantinolnicotinate (Complamin) by a 21 days infusion of 1.5 g-30 g in 500 ml NaCl 0.9% followed by 3 months 1,000 mg sustained release tablets t.i.d. An improvement in hearing was achieved in 90.5% of the cases and in 52% returned to normal. Tinnitus improved in 92% of cases and resolved completely in 54%. The results of speech and sound audiograms correlated well, and showed significant recovery in the first 3 weeks. The infusion therapy was terminated prematurely in 4 patients because of near normalization of hearing (maximum dosage: 15 g Complamin)...
July 1986: HNO
https://www.readbyqxmd.com/read/3602599/multicenter-study-on-the-treatment-of-secretory-otitis-media-with-ambroxol-importance-of-a-surface-tension-lowering-substance
#20
D Passàli, G Zavattini
Animal studies showed the presence of a surfactant substance in the Eustachian tube. On the premise that alteration of surfactant-like substance might cause pathology of the middle ear in man, a multicenter (24 ENT hospitals) double-blind trial versus placebo was carried out in 435 adults and children with secretory otitis media. Treatment was ambroxol, a drug that changes the bronchial secretions and promotes surfactant synthesis. The dosage regimen was as follows: adults--one 30-mg tablet of ambroxol 3 times/day; children--9 mg of ambroxol syrup, 4 times daily...
1987: Respiration; International Review of Thoracic Diseases
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