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laryngeal steroid injection

Ziya L Gokaslan, Mohamad Bydon, Rafael De la Garza-Ramos, Zachary A Smith, Wellington K Hsu, Sheeraz A Qureshi, Samuel K Cho, Evan O Baird, Thomas E Mroz, Michael Fehlings, Paul M Arnold, K Daniel Riew
STUDY DESIGN: Multicenter retrospective study. OBJECTIVES: To investigate the risk of symptomatic recurrent laryngeal nerve palsy (RLNP) following cervical spine surgery, to examine risk factors for its development, and to report its treatment and outcomes. METHODS: A multicenter study from 21 high-volume surgical centers from the AOSpine North America Clinical Research Network was performed. Each center screened for rare complications following cervical spine surgery, including RLNP...
April 2017: Global Spine Journal
Jung-Hae Cho, Sang-Yeon Kim, Young-Hoon Joo, Young-Hak Park, Woo-Seob Hwang, Dong-Il Sun
OBJECTIVE: This study aims to investigate the clinical efficacy and safety of immediate intralesional steroid injection in patients undergoing laryngeal microsurgery (LMS) for benign vocal fold lesions (BVFLs). STUDY DESIGN: This is a single-institution, retrospective cohort study. METHODS: Patients were divided into two groups according to whether or not they received adjunctive steroid injection after LMS. We evaluated the outcomes using objective, perceptual voice analysis and videostroboscopy...
February 28, 2017: Journal of Voice: Official Journal of the Voice Foundation
Aaron J Feinstein, Alex Goel, Govind Raghavan, Jennifer Long, Dinesh K Chhetri, Gerald S Berke, Abie H Mendelsohn
Importance: Optimal management of subglottic stenosis has not been established. Endoscopic techniques include balloon dilation, radial incisions with carbon dioxide laser or cold knife, and combinations of techniques. Adjunctive measures include mitomycin application and glucocorticoid injection. Objective: To determine whether surgical technique or adjunctive measures are associated with duration between surgical procedures. Design, Setting, and Participants: Adult patients with subglottic stenosis treated endoscopically between 1995-2015 at a quaternary academic medical center were identified...
May 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
Mitsuyoshi Imaizumi, Yasuhiro Tada, Wataru Okano, Akiko Tani, Koichi Omori
Vocal nodules are generally caused by vocal abuse, and conservative treatments such as voice therapy have been advocated as a first-choice treatment for vocal nodules. Reports of vocal fold lesions related to autoimmune diseases, such as bamboo nodules, are rare in the literature. Here we report a very rare case of bamboo nodules in a 30-year-old woman treated by steroid injection into the vocal folds by videoendoscopic laryngeal surgery in an outpatient setting. She was successfully treated without further recurrence...
April 2016: Ear, Nose, & Throat Journal
Pui Y Lee, Eelam A Adil, Alexandria L Irace, Laura Neff, Mary Beth F Son, Edward Y Lee, Antonio Perez-Atayde, Reza Rahbar
OBJECTIVE: Granulomatosis with polyangiitis (GPA) is a necrotizing inflammatory disease that can affect the airway. The purpose of this study was to present a case of pediatric laryngotracheal GPA and provide management recommendations based on a thorough review of the literature. DATA SOURCES: Retrospective chart and literature review REVIEW METHODS: A pediatric patient with laryngotracheal and pulmonary manifestations of GPA who underwent chemotherapy and intralesional corticosteroid injection is described...
January 2017: Laryngoscope
S Y Tian, J R Li, P F Guo, K L Li, H Zhang
OBJECTIVE: To study the efficacy of intralesional steroid injection combined with acid-suppressive therapy for laryngeal contact granuloma. METHODS: Eighty eight patients with laryngeal contact granuloma diagnosed from March 2010 to October 2014 were reviewed.Twenty-one patients took intralesional steroid injection combined with acid-suppressive therapy as experimental group (4 patients in initial treatment group, 17 patients in non-initial treatment group), other 67 patients only received acid-suppressive therapy as control group...
February 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Yi C Zhao, Alkis J Psaltis
PURPOSE OF REVIEW: Optimization of the surgical field involves a complex interplay of many factors. Although it is agreed that hemostasis is critical to safe, efficient, and successful sinus surgery, a lack of consensus exists as to the best way to achieve it. This review examines the current body of evidence supporting many of the practices surgeons believe to influence hemostasis. RECENT FINDINGS: Although many of the practices discussed in this article have long been considered to influence hemostasis, it is not until recently that high-level evidence supporting their use has been available...
February 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
Lucy L Shi, Laureano A Giraldez-Rodriguez, Michael M Johns
OBJECTIVE: The aim of this study was to illustrate the risk of vocal fold atrophy in patients who receive serial subepithelial steroid injections for vocal fold scar. METHODS: This study is a retrospective case report of two patients who underwent a series of weekly subepithelial infusions of 10 mg/mL dexamethasone for benign vocal fold lesion. Shortly after the procedures, both patients developed a weak and breathy voice. The first patient was a 53-year-old man with radiation-induced vocal fold stiffness...
November 2016: Journal of Voice: Official Journal of the Voice Foundation
Ravindhra G Elluru, Melanie R Friess, Gresham T Richter, J Fred Grimmer, David H Darrow, Jennifer J Shin, Jonathan A Perkins
OBJECTIVE: To evaluate the effectiveness of systemic propranolol in airway infantile hemangioma (AIH) treatment. DESIGN: Case series with chart review. PARTICIPANTS: Patients with AIH treated with propranolol between 2009 and 2012 with at least a 1-year follow-up. OUTCOMES: Presenting age, treating institution, syndrome presence, presenting AIH stage, endoscopy status, propranolol initiation location/dose/duration, time to stridor resolution, adjunctive medical and surgical therapy, and treatment-associated complications...
September 2015: Otolaryngology—Head and Neck Surgery
Nicolas Javaud, Anne Gompel, Laurence Bouillet, Isabelle Boccon-Gibod, Delphine Cantin, Nadia Smaiti, Françoise Carpentier, Marouane Boubaya, David Launay, Frédéric Adnet, Olivier Fain
BACKGROUND: Acute attacks of hereditary angioedema are characterized by recurrent localized edema. These attacks can be life threatening and are associated with substantial morbidity and mortality. OBJECTIVE: To determine factors associated with hospital admission of patients with an acute attack of hereditary angioedema presenting at the emergency department. METHODS: This was a multicenter prospective observational study of consecutive patients (January 2011 through December 2013) experiencing an acute hereditary angioedema attack and presenting at the emergency department at 1 of 4 French reference centers for bradykinin-mediated angioedema...
June 2015: Annals of Allergy, Asthma & Immunology
J Todic, V Schweizer, I Leuchter
Bamboo nodes are sub mucous lesions localized in the vocal folds. Their aspect reminds of the nodes in a bamboo, which gives them their name. The diagnosis is made by laryngoscopy. Those lesions are always associated with autoimmune diseases: systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, Hashimoto, progressive systemic sclerosis. The treatment is not clearly described in literature. It is recommended to start with systemic steroids and speech therapy. If the regression of laryngeal lesions is not suf- ficient, it is advised to complete with local steroid injections...
October 1, 2014: Revue Médicale Suisse
J Todic, V Schweizer, I Leuchter
Bamboo nodes are sub mucous lesions localized in the vocal folds. Their aspect reminds of the nodes in a bamboo, which gives them their name. The diagnosis is made by laryngoscopy. Those lesions are always associated with autoimmune diseases: systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, Hashimoto, progressive systemic sclerosis. The treatment is not clearly described in literature. It is recommended to start with systemic steroids and speech therapy. If the regression of laryngeal lesions is not suf- ficient, it is advised to complete with local steroid injections...
October 1, 2014: Revue Médicale Suisse
Jue Xu, Tao Xue, Ying Bao, Dong-Hai Wang, Bing-Liang Ma, Chen-Yi Yin, Guang-Hui Yang, Gang Ren, Long-Jiang Lan, Jian-Qiu Wang, Xiao-Lan Zhang, Yu-Qin Zhao
PURPOSE: Vocal fold leukoplakia is a premalignant precursor of squamous cell carcinoma. Although many efforts have been contributed to therapy of this disease, none exhibits a satisfactory result. The aims of this study were to investigate the effectiveness and feasibility of andrographolide therapy in vocal fold leukoplakia and to explore the preliminary mechanism underlying. MATERIALS AND METHODS: Forty-one eligible patients were enrolled in the study. The patients were treated for 10-minute exposures of 5 ml (25mg/ml) andrographolide injection aerosols twice a day, and 2 weeks was considered as one treatment course...
March 2014: American Journal of Otolaryngology
Seung Won Lee, Hyung Jun Hong, Seung Ho Choi, Dong Il Sun, Young Hak Park, Byung Joo Lee, Seong Keun Kwon, Il Seok Park, Sang Hyuk Lee, Young-Ik Son
OBJECTIVES/HYPOTHESIS: This study evaluated the efficacy of commonly used treatment modalities and determined predictors of treatment outcome for contact granuloma. STUDY DESIGN: Retrospective study. METHODS: Twenty otolaryngologists from 18 university hospitals reviewed the medical records of their own contact granuloma patients for the most recent 4 years. To be enrolled as a valid case, each treatment had to continue for at least 3 months...
May 2014: Laryngoscope
Chi-Te Wang, Li-Jen Liao, Mei-Shu Lai, Po-Wen Cheng
OBJECTIVES/HYPOTHESIS: This study intends to objectively quantify and compare the regression rates of vocal lesions in patients receiving either vocal fold steroid injection (VFSI) or vocal hygiene education (VHE). Potential influence of occupational vocal demands on the treatment outcome was also investigated. STUDY DESIGN: Retrospective case series. METHODS: This study enrolled 176 patients of vocal nodules and vocal polyps. Ninety-two patients received VFSI, while 84 patients received VHE...
February 2014: Laryngoscope
Hee-Jin Jin, Sang-Hyuk Lee, Seon-Uk Lee, Hyun-Sub Lee, Sung-Min Jin, Dong-Hun Kim, Seung-Wan Chae, Jin-Hee Sohn
OBJECTIVES/HYPOTHESIS: The purpose of this study was to investigate the morphological and histological change of vocal folds (VFs) after steroid injection in a rabbit model. STUDY DESIGN: Prospective animal study. SETTING: Tertiary academic medical center. SUBJECTS AND METHODS: Twenty-four New Zealand white rabbits were used in this study. We randomly classified rabbits into the 3 groups and triamcinolone acetonide suspension was injected to the right VF with different concentrations...
August 2013: Otolaryngology—Head and Neck Surgery
Albert L Sheffer, Andrew J MacGinnitie, Marilyn Campion, Leslie E Stolz, William E Pullman
BACKGROUND: Hereditary angioedema (HAE) is a rare disorder associated with episodic attacks of well-demarcated angioedema. Attacks that affect the larynx can result in life-threatening airway obstruction. OBJECTIVES: To examine efficacy and safety of ecallantide treatment for laryngeal HAE attacks. METHODS: Data were combined from 4 clinical studies (EDEMA2, EDEMA3, EDEMA4, and DX-88/19) evaluating 30 mg of subcutaneous ecallantide for treatment of acute HAE attacks...
March 2013: Annals of Allergy, Asthma & Immunology
C Kwang Sung, Gabriel J Tsao
OBJECTIVES: A number of laryngeal injection techniques have been described for performing vocal fold medialization or delivery of medications, including peroral and percutaneous approaches. Although flexible nasolaryngoscopy-guided injection (FNGI) improves visualization and patient tolerance over rigid endoscopy, the technique requires an assistant to manipulate the laryngoscope. The efficacy and patient tolerance of a novel, single-operator technique for FNGI are evaluated. METHODS: Patients who required laryngeal injection for vocal fold medialization or for administration of cidofovir or steroids were included in this study...
January 2013: Annals of Otology, Rhinology, and Laryngology
Shi-Min Yuan
BACKGROUND: The clinical characteristics and outcomes of hoarseness subsequent to cardiovascular surgery, intervention, maneuver and endotracheal intubation have not been systematically elucidated. METHODS: The literature of hoarseness following cardiovascular surgery, intervention, and maneuver and intubation published between 1980 and 2011 was comprehensively retrieved in the MEDLINE database and the Google and Highwire Press search engines. RESULTS: The so-called "iatrogenic Ortner's (cardiovocal) syndrome" developed 0-7 (2...
2012: Cardiology Journal
Chi-Te Wang, Li-Jen Liao, Po-Wen Cheng, Wu-Chia Lo, Mei-Shu Lai
OBJECTIVE: Emerging literature had documented the potential usefulness of vocal fold steroid injection (VFSI) as an alternative treatment option for benign vocal lesions. This study aims to conduct a qualitative synthesis and quantitative meta-analysis of vocal fold steroid injection STUDY DESIGN: Systematic review and meta-analysis. METHODS: Electronic databases were searched using relevant keywords. Extracted data include author, year of publication, diagnosis, steroid regimen, recurrence and side effects...
January 2013: Laryngoscope
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