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https://www.readbyqxmd.com/read/28101206/primary-chondrosarcoma-of-the-thyroid-cartilage-surgery-based-management-of-a-rare-case
#1
Guo-Hua Sun, Yuan-Jin Wang, Li-Li Gao, Ning Qu, Xiang-Ming Mu, Rong-Liang Shi, Qing-Hai Ji
In this study, we present a case of a 52-year-old male with a chondrosarcoma of the left lamina of the thyroid cartilage. Pre-operative evaluations detected typical calcifications and delineated the extent of the tumor. The patient underwent a total laryngectomy to ensure the complete resection of the tumor. The tumor was histopathologically found to consist of chondrocytes in a hyaline cartilage matrix. The patient's post-operative course has been successful apart from the permanent tracheostomy. Herien, we discuss the methods and rationales for the diagnosis and management of and recovery from this rare tumor, and also provide a review of the literature...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28095938/effect-of-the-patient-to-patient-communication-model-on-dysphagia-caused-by-total-laryngectomy
#2
L Tian, R An, J Zhang, Y Sun, R Zhao, M Liu
OBJECTIVE: The study aimed to evaluate the effect of a patient-to-patient communication model on dysphagia in laryngeal cancer patients after total laryngectomy. METHODS: Sixty-five patients who had undergone total laryngectomy were randomly divided into three groups: a routine communication group, a patient communication group (that received the patient-to-patient communication model) and a physician communication group. Questionnaires were used to compare quality of life and swallowing problems among all patient groups...
January 18, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28093768/short-term-and-long-term-follow-up-of-pulmonary-function-in-patients-with-copd-after-total-laryngectomy-a-prospective-study
#3
Charlotte Schönwald, Maria Isabel Körber, Dirk Beutner, Roman Pfister, Konrad Frank, Orlando Guntinas-Lichius, Guido Michels
OBJECTIVE: There exists no standardized method for examining lung function in laryngectomized patients. STUDY DESIGN AND METHODS: We established a base plate adapter (BPA) system for patients after laryngectomy. In 10 patients with chronic obstructive pulmonary disease (COPD), we evaluated pulmonary function before laryngectomy, as well as 2 weeks and 3 months after laryngectomy. RESULTS: The BPA system was well tolerated and delivered reliable results comparable to measurements with a mouthpiece...
January 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28054142/extent-of-thyroid-resection-and-thyroid-function-after-postoperative-radiotherapy-following-total-laryngectomy-or-total-pharyngo-laryngo-esophagectomy
#4
Kiyoaki Tsukahara, Rio Kojima, Ray Motohashi, Takuro Okada, Masanori Yatomi, Yasuaki Katsube, Atsuo Takeda, Ayumi Agata, Yasuo Ogawa
OBJECTIVE: Concurrent chemoradiotherapy (CCRT) is often performed after total pharyngo-laryngo-esophagectomy (TPLE) or total laryngectomy (TL). Hypothyroidism is one of the side-effects of CCRT. The objective of this study was to ascertain the timing of onset and severity of latent hypothyroidism among patients who underwent radiotherapy (RT) or CCRT after TPLE or TL, using thyroid-stimulating hormone (TSH) as a biomarker, and to explore methods of preventing its development. METHODS: Participants comprised 21 patients who underwent these treatments at Tokyo Medical University Hachioji Medical Center between May 2009 and December 2013...
January 4, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28052218/implantation-of-an-artificial-larynx-after-total-laryngectomy
#5
LETTER
Christian Debry, N Engin Vrana, Agnès Dupret-Bories
No abstract text is available yet for this article.
5, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28052013/association-of-genetic-polymorphisms-with-laryngeal-carcinoma-prognosis-in-a-chinese-population
#6
Fang Quan, Feipeng Zhang, Yanxia Bai, Long Zhou, Hua Yang, Bin Li, Tianbo Jin, Huajing Li, Yuan Shao
We analyzed the effects of single-nucleotide polymorphisms (SNPs) on laryngeal carcinoma (LC) risk and overall survival (OS) in 170 Chinese male LC patients followed for 10 years. After assessment of clinical characteristics (age, laryngectomy, neck dissection, tumor differentiation, TNM status), the patients were genotyped for 24 SNPs associated with risk in multiple cancers. LC risk was assessed using log-rank test and Cox proportional hazard models. The median OS time was 48 months. By the follow-up deadline, OS was 41...
December 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/28049900/effect-of-medical-educational-lectures-by-pharmacists-for-understanding-and-relieving-post-laryngectomy-symptoms
#7
Naomi Hyoguchi, Toshio Kubota, Daisuke Kobayashi, Takao Shimazoe
 Patients who underwent total laryngectomy (TL) are limited in their access to health information and have reduced quality of life because of difficulties in communicating with health providers. Understanding the method for coping with symptoms after TL is important to self-control. However, their understanding and relief regarding the method including medicine use are not well known. In this study, we conducted a current situation survey about symptoms after TL and held medical educational lectures (ML) by pharmacists for the patients...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28047883/su-f-t-442-dose-distribution-comparison-for-post-laryngectomy-stoma-area-between-conventional-ap-and-vmat-plans-with-or-without-bolus
#8
B Lee, J Zhang, M Leu, J Cho-Lim, W Inouye, W Lorentz, S Lee
PURPOSE: To compare dose distributions of conventional AP vs. VMAT treatment plans with or without bolus around post-laryngectomy stoma. METHODS: Radiation dose coverage for post-laryngectomy stoma was analyzed using a set of real-case CT-simulation images. After meticulous contouring of the catheter cuff, stoma lumen, peri-stoma skin and subclinical tumor bed at the larynx, the resulting dosimetry plans were analyzed with or without a 5 mm bolus placement. Wet gauze was used to minimize the effect of any air gap...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28033526/induction-chemotherapy%C3%A2-followed-by-radiotherapy-for-larynx-preservation-in-advanced-laryngeal-and-hypopharyngeal-cancer-outcome-prediction-after-one-cycle-induction-chemotherapy-by-a-score-based-on-clinical-evaluation-computed-tomography-based-volumetry%C3%A2-and
#9
Gunnar Wichmann, Anne Krüger, Andreas Boehm, Marlen Kolb, Mathias Hofer, Milos Fischer, Stefan Müller, Sandra Purz, Patrick Stumpp, Osama Sabri, Andreas Dietz, Regine Kluge
BACKGROUND: Long-term laryngectomy-free (LFS), tumour-specific (TSS) and overall survival (OS) is achieved by non-surgical larynx preservation (LP) only in a proportion of patients with locally advanced laryngeal or hypopharyngeal cancer. A score facilitating decision-making after 1 cycle induction chemotherapy (IC-1) may improve LFS and TSS. METHODS: Early response to IC-1 with TPF ± cetuximab was assessed in 52 patients using endoscopic tumour staging for selecting total laryngectomy for non-responders with endoscopic tumour surface shrinkage <30% versus induction chemotherapy plus radiotherapy (IC + RT) for responders...
December 26, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28026864/complications-hospital-length-of-stay-and-readmission-after-total-laryngectomy
#10
Ryan P Goepfert, Katherine A Hutcheson, Jan S Lewin, Neha G Desai, Mark E Zafereo, Amy C Hessel, Carol M Lewis, Randal S Weber, Neil D Gross
BACKGROUND: The purpose of this study was to describe the 30-day incidence of complications after total laryngectomy (TL) in a high-volume institution and their impact on the hospital length of stay (LOS) and readmission rates. METHODS: A retrospective cohort study of all patients who underwent TL at The University of Texas MD Anderson Cancer Center from January 1, 2010 through June 30, 2013 was conducted. The patient demographics, treatment history, LOS, and 30-day post-TL complications and readmissions were extracted from the medical record...
December 27, 2016: Cancer
https://www.readbyqxmd.com/read/28025603/evidence-and-evidence-gaps-of-laryngeal-cancer-surgery
#11
REVIEW
Susanne Wiegand
Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number or organ preservation surgical techniques, like open partial laryngectomy, transoral laser microsurgery, and transoral robotic surgery have been developed. Studies on laryngeal cancer surgery are mainly retrospective case series and cohort studies. The evolution of chemoradiation protocols and their analysis in prospective randomized trials have led to an increasing acceptance of non-surgical treatment procedures...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/28011997/do-salivary-bypass-tubes-lower-the-incidence-of-pharyngocutaneous-fistula-following-total-laryngectomy-a-retrospective-analysis-of-predictive-factors-using-multivariate-analysis
#12
Robert W A Hone, Eqramur Rahman, Gentle Wong, Yvette Annan, Victoria Alexander, Ali Al-Lami, Kiran Varadharajan, Michael Parker, Ricard Simo, Lisa Pitkin, Alasdair Mace, Enyinnaya Ofo, Alistair Balfour, Iain J Nixon
Salivary bypass tubes (SBT) are increasingly used to prevent pharyngocutaneous fistula (PCF) following laryngectomy and pharyngolaryngectomy. There is minimal evidence as to their efficacy and literature is limited. The aim of the study was to determine if SBT prevent PCF. The study was a multicentre retrospective case control series (level of evidence 3b). Patients who underwent laryngectomy or pharyngolaryngectomy for cancer or following cancer treatment between 2011 and 2014 were included in the study...
December 23, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28011050/could-the-addition-of-cetuximab-to-conventional-radiation-therapy-improve-organ-preservation-in-those-patients-with-locally-advanced-larynx-cancer-who-respond-to-induction-chemotherapy-an-organ-preservation-spanish-head-and-neck-cancer-cooperative-group-phase
#13
Ricard Mesía, Jose A Garcia-Saenz, Alicia Lozano, Miguel Pastor, Juan J Grau, Javier Martínez-Trufero, Julio Lambeaz, Joaquina Martínez-Galán, Jose R Mel, Belen González, Silvia Vázquez, Manel Mañós, Miren Taberna, Beatriz Cirauqui, Elvira Del Barco, Esther Casado, Jordi Rubió-Casadevall, Angles Rodríguez-Jaráiz, Juan J Cruz
PURPOSE: To evaluate the efficacy and safety of induction chemotherapy (IC) followed by bioradiotherapy (BRT) to achieve functional larynx preservation in the setting of locally advanced head and neck tumors. METHODS AND MATERIALS: This was a phase 2, open-label, multicenter study of patients with stage III and IVA laryngeal carcinoma who were candidates for total laryngectomy. The primary endpoint was the rate of survival with functional larynx (SFL) at 3 years, with a critical value to consider the study positive of SFL >59%...
November 17, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28005774/a-simple-closure-technic-for-tracheoesophageal-puncture-failures
#14
Ahmet Mutlu, Sinem Dasli, Murat Ozturk, Murat Topdag
Tracheosephageal puncture is the one of the most favorable methods, and widely used by physicians for voice reconstruction after total laryngectomy. Intractable leakages from the tracheosephageal punctures are the most common complication, and management of these fistulas is still troublesome for the patients and physicians. Local surgical sutures, rotational flaps, injections are reported previously, but in this report the authors aimed to mention on a very simple method with silicone septal button. Insertion of a temporary silicone septal button may be well tolerated by patients and can help to manage this complication easily on exact indications...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28004260/the-influence-of-closure-technique-in-total-laryngectomy-on-the-development-of-a-pseudo-diverticulum-and-dysphagia
#15
Martine F van der Kamp, Rico N P M Rinkel, Simone E J Eerenstein
OBJECTIVE: In total laryngectomy, the neopharynx can be closed in several ways. It is suggested that a pseudo-diverticulum is seen more frequently in patients closed with vertical closure than with "T"-shaped closure, causing postoperative dysphagia. We report the results of patients treated with vertical closure and "T"-shaped closure with regard to the formation of a pseudo-diverticulum and postoperative dysphagia. METHODS: In our retrospective cohort study, we identified 117 consecutive laryngectomized patients treated in the VU University Medical Center of Amsterdam between March 2009 and December 2013...
December 21, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28000237/predictors-of-length-of-stay-reoperation-and-readmission-following-total-laryngectomy
#16
Samuel N Helman, Jason A Brant, Sami P Moubayed, Jason G Newman, Steven B Cannady, Raymond L Chai
OBJECTIVES/HYPOTHESIS: To identify relevant patient and surgical risk factors associated with prolonged length of stay, return to the operating room, and readmission within 30 days following total laryngectomy using the American College of Surgeons National Quality Improvement Program (ACS-NSQIP) STUDY DESIGN: Retrospective database study. Patients undergoing total laryngectomy alone for laryngeal cancer were identified from the ACS-NSQIP database from 2005 to 2014. METHODS: Multivariate logistic regression was used to identify independent predictors for prolonged length of stay, readmissions, and unplanned reoperations within 30 days...
December 21, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27988198/primary-total-laryngectomy-and-pharyngolaryngectomy-in-t4-pharyngolaryngeal-cancers-oncologic-and-functional-results-and-prognostic-factors
#17
M Roux, O Dassonville, M Ettaiche, E Chamorey, G Poissonnet, A Bozec
OBJECTIVES: The aims of this study were to assess oncologic and functional outcome in primary total laryngectomy or pharyngolaryngectomy (TL/TL/TPL) for laryngeal or hypopharyngeal cancer with extra-laryngeal extension (T4) and to determine the predictive factors of these results. MATERIAL AND METHODS: A retrospective analysis was performed on the computerized medical records of all patients undergoing primary TL/TPL for T4 larynx or hypopharynx squamous cell carcinoma between 2000 and 2014 at our institution...
December 14, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/27969030/standardizing-nurse-training-strategies-to-improve-knowledge-and-self-efficacy-with-tracheostomy-and-laryngectomy-care
#18
Katie McDonough, Janet Crimlisk, Patrice Nicholas, Howard Cabral, Emily K Quinn, Scharukh Jalisi
OBJECTIVE: Appropriate tracheostomy and laryngectomy care requires that nurses maintain specific knowledge and a particular skillset, to ensure safe, competent care. Deficiencies in this nursing care remain a persistent problem. The objective of this study was to evaluate the effect of a nurse training program on knowledge and self-efficacy with tracheostomy and laryngectomy care. STUDY DESIGN: Prospective, interventional survey design. SETTING: Academic, tertiary care hospital between September 2014 and April 2015...
November 2016: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/27958601/open-partial-horizontal-laryngectomies-is-it-time-to-adopt-a-modular-form-of-consent-for-the-intervention
#19
L Giordano, D Di Santo, E Crosetti, A Bertolin, G Rizzotto, G Succo, M Bussi
Nowadays, open partial horizontal laryngectomies (OPHLs) are well-established procedures for treatment of laryngeal cancer. Their uniqueness is the possibility to modulate the intervention intraoperatively, according to eventual tumour extension. An OPHL procedure is not easy to understand: there are several types of procedures and the possibility to modulate the intervention can produce confusion and lack of adherence to the treatment from the patient. Even if the surgery is tailored to a patient's specific lesion, a unified consent form that discloses any possible extensions, including a total laryngectomy, is still needed...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958597/salvage-total-laryngectomy-after-conservation-laryngeal-surgery-for-recurrent-laryngeal-squamous-cell-carcinoma
#20
A De Virgilio, A Greco, F Bussu, A Gallo, D Rosati, S-H Kim, C-C Wang, M Conte, G Pagliuca, M De Vincentiis
The aim of the present study was to evaluate the oncological efficacy of salvage total laryngectomy in patients who had previously undergone supracricoid partial laryngectomy or transoral laser microsurgery for treatment of laryngeal squamous cell carcinoma. We retrospectively reviewed the medical, surgical and pathological records of 35 patients who underwent salvage total laryngectomy after recurrence of laryngeal cancer (following supracricoid partial laryngectomy or transoral laser microsurgery). Kaplan-Meier survival curves as well as univariate and multivariate analyses of prognostic factors were performed...
October 2016: Acta Otorhinolaryngologica Italica
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