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https://www.readbyqxmd.com/read/27932525/the-pharyngoesophageal-segment-after-total-laryngectomy
#1
Beatriz Arenaz Búa, Rolf Olsson, Ulla Westin, Roland Rydell
OBJECTIVE: The aim of the present study was to characterize the pharyngoesophageal segment in laryngectomees who rated themselves as functional tracheoesophageal speakers. METHODS: Voice perceptual assessment, high-resolution videomanometry of swallowing and phonation, and high-speed camera recording during phonation provided information about the anatomy and function of the pharyngoesophageal segment. RESULTS: Fourteen patients were included in the study...
December 7, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27919993/laryngo-esophageal-dysfunction-free-survival-in-a-preservation-protocol-for-t3-laryngeal-squamous-cell-carcinoma
#2
Philippe Gorphe, Margarida Matias, Caroline Even, Charles Ferte, François Bidault, Gabriel Garcia, Stéphane Temam, France Nguyen, Pierre Blanchard, Yungan Tao, François Janot
BACKGROUND: We reviewed the outcomes of patients with T3 laryngeal neoplasms with a fixed hemilarynx, a large gross tumor volume or a subglottic extension (SGE), treated with a laryngeal-preservation protocol with induction chemotherapy. PATIENTS AND METHODS: The study end-points were laryngo-esophageal dysfunction-free survival (LEDFS), laryngectomy-free survival (LFS), overall survival (OS), and disease-free survival (DFS). RESULTS: A total of 104 patients were included...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27916282/repair-of-complex-pharyngocutaneous-fistula-using-a-staged-temporoparietal-fascial-flap
#3
Nicholas B Abt, Priya Srikanth, Sidharth V Puram, Daniel G Deschler
INTRODUCTION: PCF is the most common major complication after salvage total laryngectomy (TL), especially for previously irradiated patients with laryngeal or hypopharyngeal cancer. METHODS/RESULTS: A 65-year-old woman presented with recurrent bilateral supraglottic SCC requiring salvage TL 5.5years after initial T1N0M0 epiglottic SCC resection. Her post-operative course was complicated by PCF development one month post-operatively and surgical fistula closure was delayed for adjuvant chemoradiotherapy...
November 25, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27916009/insertion-of-a-tracheoesophageal-speech-valve-a-novel-approach-in-a-difficult-situation
#4
C P Yiannakis, R B Townsley, I G Smillie, G L Picozzi
BACKGROUND: Functional voice rehabilitation is becoming increasingly important following total laryngectomy and pharyngolaryngectomy. Tracheoesophageal voice via a shunt valve is currently regarded as the 'gold standard' for voice rehabilitation. Traditional techniques usually allow for the replacement of valves in the out-patient setting; however, patient factors such as altered anatomy may occasionally prevent this. OBJECTIVE: This paper describes a novel approach for speech valve insertion that is safe, quick and cost-effective, and which uses equipment commonly available in ENT wards and the operating theatre...
December 5, 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27893554/stapler-esophageal-closure-during-total-laryngectomy
#5
Onur Ismi, Murat Unal, Yusuf Vayisoglu, Mesut Yesilova, Ilter Helvaci, Kemal Gorur, Cengiz Ozcan
Mechanical esophageal closure with stapler during total laryngectomy has been used by various authors to decrease the surgical time and pharyngocutaneous fistula (PCF) rates. In a few of the studies, surgical site infection (SSI) rates are mentioned and none of the studies emphasize the effect of decreased surgical time on postoperative cardiovascular and cerebrovascular complications. In this study, the authors compared the PCF rates, SSI rates, operation times between 30 mechanical stapler and 40 manual esophageal closure during total laryngectomy for laryngeal cancer patients...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27891275/tortuous-carotid-artery-extended-to-neck-level-iib-mimicking-the-metastatic-mass
#6
Lokman Uzun, Oğuz Kadir Eğilmez, M Tayyar Kalcioglu, Muhammet Tekin
Specifically in neck level IIb, the expected normal anatomy does not contain any vital structures and consequently it might direct a surgeon to perform rapid surgical dissection of tissues. Therefore aberrant anatomy of the vessels in the patients may be overlooked during neck dissection. Unexpected and potentially devastating injuries can be avoided by respecting the possible aberrant anatomy in any level of the neck. In this case report, a 74-year-old man was presented with laryngeal carcinoma who was treated with laryngectomy and bilateral neck dissection...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27888826/clinical-significance-of-ki-67-c-erbb-2-and-e-cadherin-expressions-in-open-partial-laryngectomy-patients
#7
Ozan Barutçu, Medine Kara, Aslı Muratlı, Oğuz Güçlü, Sefa Dereköy
OBJECTIVES: This study aims to analyze the correlation between biomarkers and risks of cervical lymph node invasion, recurrence, distant metastasis and survival regarding the clinicopathological variables in laryngeal cancers. PATIENTS AND METHODS: Forty-one patients with laryngeal cancers were examined retrospectively. The correlations evaluated between E-cadherin, Ki-67, c-erbB-2 expressions, tumor site, differentiation, the risk of cervical lymph node metastasis, perineural, perivascular, pericapsular invasion and recurrence as well as survival time...
September 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27888508/outcomes-following-laryngectomy-refusal-after-insufficient-response-to-induction-chemotherapy
#8
Philippe Gorphe, Margarida Matias, Pierre Blanchard, Caroline Even, Charles Ferte, Yungan Tao, Stéphane Temam, François Bidault, François Janot
OBJECTIVE: To review patients who refused a total laryngectomy and were treated with radiotherapy (RT) after insufficient response to induction chemotherapy in a larynx preservation protocol for advanced-stage cancer of the larynx and to compare their outcomes with good responders. STUDY DESIGN: Retrospective cohort study. METHODS: Eighty-six patients treated with induction chemotherapy followed by RT were included in the analysis: 75 good responders and 11 insufficient responders who refused surgery...
November 26, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27882709/technical-note-using-a-tracheal-stent-for-conservative-management-of-speaking-valve-associated-tracheo-oesophageal-fistula
#9
M Cunnane, S Patil, R Sothinathan, D Walker, M Gaulton, L Pitkin
Surgical voice rehabilitation is an essential dimension of treatment following total laryngectomy. The gold standard is tracheo-oesophageal puncture and speaking valve placement. Whilst offering excellent phonation in many patients, there is a well-documented risk of valve associated fistula formation, the incidence of which varies from 1 to 21% (1) . Risk factors for delayed valve associated tracheo-oesophageal fistula include post chemo-radiotherapy (salvage laryngectomy), oesophageal stricture, persistent fungal infection and poor patient compliance in managing their speaking valve(2) ...
November 24, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27879602/health-related-quality-of-life-following-reconstruction-for-common-head-and-neck-surgical-defects
#10
Wess A Cohen, Claudia R Albornoz, Peter G Cordeiro, Jennifer Cracchiolo, Elizabeth Encarnacion, Meghan Lee, Michele Cavalli, Snehal Patel, Andrea L Pusic, Evan Matros
BACKGROUND: Improved understanding and management of health-related quality of life represents one of the greatest unmet needs for patients with head and neck malignancies. The purpose of this study was to prospectively measure health-related quality of life associated with different anatomical (head and neck) surgical resections. METHODS: A prospective analysis of health-related quality of life was performed in patients undergoing surgical resection with flap reconstruction for stage II or III head and neck malignancies...
December 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27871805/the-survival-rate-and-larynx-preservation-in-elderly-cancer-patients-who-received-surgical-operation-a-retrospective-cohort-study
#11
Qin Wang, Yehai Liu, Guoqin Hu, Ruokun Wang, Yi Zhao, Ming Zhang
BACKGROUND: To investigate the efficiency of surgical operation for patients over 70 years with hypopharyngeal cancer. MATERIALS AND METHODS: A retrospective analysis of the medical records from 68 patients over 70 years-old with hypopharyngeal cancer who underwent different therapeutic regimen between 2000 and 2009 was conducted. 36 of 68 patients underwent larynx preservation. All patients were treated with surgical operation and adjuvant radiotherapy. A Kaplan-Meier method was employed to calculate the survival rate...
November 15, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27865371/assessing-head-and-neck-cancer-patient-preferences-and-expectations-a-systematic-review
#12
REVIEW
Pierre Blanchard, Robert J Volk, Jolie Ringash, Susan K Peterson, Katherine A Hutcheson, Steven J Frank
INTRODUCTION: To enhance the value of care, interventions should aim at improving endpoints that matter to patients. The preferences of head and neck cancer patients regarding treatment outcomes are therefore a major topic for patient-centered research. METHODS: A systematic review (PROSPERO number CRD42016035692) was conducted by searching electronic databases (Medline, Embase, Cochrane, CINAHL) for articles evaluating patient or surrogate preferences in head and neck cancer...
November 2016: Oral Oncology
https://www.readbyqxmd.com/read/27846642/-stomal-cancer-recurrency-a-clinic-pathological-consideration
#13
S Teutsch, M Bas, H Bier, A Knopf
Objectives: Analysis of pre-operative tracheostomy and circumjacent tumour free margins as risk factors in the development of stomal recurrent disease after (pharyngo)laryngectomy. Material and Methods: 124 patients after (pharyngo)laryngectomy were analyzed for disease related data and tumour samples were analyzed for tumour free margins. The overall cohort was divided into patients with/withour pre-operative tracheostomy. Results: 18 patients suffered from recurrent disease (10 stomal, 8 distant metastases)...
November 15, 2016: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27846104/validation-of-the-chinese-version-of-the-readiness-for-hospital-discharge-scale-on-patients-who-have-undergone-laryngectomy
#14
Huiling Zhao, Xianqiong Feng, Rong Yu, Deying Gu, Xiaoqin Ji
BACKGROUND: The Readiness for Hospital Discharge Scale (RHDS) was designed to assess the readiness of patients for discharge. The original English-language instrument has shown high degrees of reliability and validity, but no Chinese version of the scale has been verified. PURPOSE: The purpose of this study was to translate the RHDS into Chinese and assess the psychometric properties of this scale on laryngectomy patients in China. METHODS: The RHDS was translated into Chinese using forward and back translation, semantic equivalence assessment, and pilot testing...
December 2016: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/27833963/anterior-commissure-laryngeal-neoplasm-endoscopic-management
#15
Nicolae Constantin Balica, Mărioara Poenaru, Eugen HoraŢiu Ştefănescu, Eugen Radu Boia, Caius Ion Doroş, Flavia Baderca, Octavian Mazilu
The CO2 laser surgery represents a treatment method of laryngeal bicordal and anterior commissure glottic cancer T1b, T2, N0. In Department of ENT, Timisoara, Romania, during 1.01.2001-31.12.2011 were analyzed 781 files from patients with laryngeal neoplasm. One hundred twenty-seven patients presented the tumor that involved both vocal cords and anterior commissure, stages T1b, T2 and T3. Therapeutic options included CO2 laser microsurgical excision for 55 (43.30%) patients, frontolateral hemilaryngectomy for 16 (12...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27833247/malignant-tumors-of-the-larynx-clinicopathologic-profile-and-implication-for-late-disease-presentation
#16
Ayotunde James Fasunla, Oluwole Agboola Ogundoyin, Paul Adekunle Onakoya, Onyekwere George Nwaorgu
BACKGROUND: Malignant laryngeal tumors are uncommon. Late presentation of the disease may worsen management outcomes. We described the epidemiologic, clinicopathologic profile, and management outcomes of laryngeal tumors in a tertiary health institution in Nigeria. MATERIALS AND METHODS: An 11-year retrospective review of medical records of patients managed for malignant laryngeal tumor at the University College Hospital, Ibadan, Nigeria, was performed. RESULTS: There were 97 patients comprising 74 (76...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27831517/nasal-and-tracheal-cytological-changes-after-total-laryngectomy-in-long-term-survivors
#17
Giuseppe Riva, Monica Boita, Andrea Corvino, Matteo Sensini, Daniela Peruzzetto, Luigi Chiusa, Giancarlo Pecorari, Massimiliano Garzaro
OBJECTIVE: Complete separation of upper and lower respiratory tract after total laryngectomy results in permanent effects on nasal cavities and tracheo-bronchial airways. Aim of this study is evaluating nasal and tracheal cytological alterations of mucosa in laryngectomy long-term survivors, analyzing the feasibility of scraping for cytological examination of tracheal mucosa. METHODS: Twenty-five laryngectomy patients underwent symptoms' evaluation, endoscopic fiber optic examination, prick tests, and nasal and tracheal scraping for cytological exam...
November 9, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27799228/synchronous-perforations-of-the-oesophagus-and-stomach-by-air-insufflation-an-uncommon-complication-of-endoscopic-dilation
#18
Arthur M Fung, Fion S Chan, Ian Y Wong, Simon Law
A 72-year-old woman had a history of carcinoma of the hypopharynx treated by total laryngectomy, circumferential pharyngectomy and free jejunal graft. Endoscopic dilation of the pharyngojejunal anastomotic stricture resulted in synchronous perforations of the oesophagus and stomach. We postulate that the perforations were caused by high intraoesophageal and intragastric pressure resulted from air insufflation during the procedure; in a situation simulating closed-loop obstruction, because of proximal obstruction by the endoscope at the stricture site and distal obstruction by pylorospasm...
October 31, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27798871/radiotherapy-associated-furin-expression-and-tumor-invasiveness-in-recurrent-laryngeal-cancer
#19
Myungjin Lee, Chang Hwan Ryu, Hyo Won Chang, Gui Chul Kim, Seong Who Kim, Sang Yoon Kim
BACKGROUND/AIM: Recurrent laryngeal cancer often shows an aggressive phenotype after radiotherapy and does not respond to conventional therapeutic strategies. In this study, we investigated the contribution of furin to cellular invasiveness in radio-resistant laryngeal cancer. MATERIALS AND METHODS: Using previously established AMC-HN-3 and AMC-HN-8 cell lines from laryngeal carcinoma patients, recurrent laryngeal cancer models were generated by cumulative irradiation (AMC-HN-3-70Gy and AMC-HN-8-70Gy)...
October 2016: Anticancer Research
https://www.readbyqxmd.com/read/27793000/dirc3-and-near-nabp1-genetic-polymorphisms-are-associated-laryngeal-squamous-cell-carcinoma-patient-survival
#20
Zhen Shen, Wanli Ren, Yanxia Bai, Zhengshuai Chen, Jingjie Li, Bin Li, Tianbo Jin, Peilong Cao, Yuan Shao
Laryngeal squamous cell carcinoma (LSCC) is one of the most common and aggressive malignancies of the upper digestive tract. The present study is a retrospective analysis of data from a prospective longitudinal study. A total of 170 male LSCC patients (average age, 60.75±10.082) at the First Affiliated Hospital of Xi'an Jiaotong University School of Medicine were recruited between January 2002 and April 2013 for this study. We assessed correlations between patient characteristics and survival, and sequenced genomic DNA from patient peripheral blood samples...
October 25, 2016: Oncotarget
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