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https://www.readbyqxmd.com/read/29744935/fast-magnetic-resonance-fingerprinting-for-dynamic-contrast-enhanced-studies-in-mice
#1
Yuning Gu, Charlie Y Wang, Christian E Anderson, Yuchi Liu, He Hu, Mette L Johansen, Dan Ma, Yun Jiang, Ciro Ramos-Estebanez, Susann Brady-Kalnay, Mark A Griswold, Chris A Flask, Xin Yu
PURPOSE: The goal of this study was to develop a fast MR fingerprinting (MRF) method for simultaneous T1 and T2 mapping in DCE-MRI studies in mice. METHODS: The MRF sequences based on balanced SSFP and fast imaging with steady-state precession were implemented and evaluated on a 7T preclinical scanner. The readout used a zeroth-moment-compensated variable-density spiral trajectory that fully sampled the entire k-space and the inner 10 × 10 k-space with 48 and 4 interleaves, respectively...
May 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29732610/image-reconstruction-algorithm-for-motion-insensitive-mr-fingerprinting-mrf-morf
#2
Bhairav Bipin Mehta, Dan Ma, Eric Yann Pierre, Yun Jiang, Simone Coppo, Mark Alan Griswold
PURPOSE: The purpose of this study is to increase the robustness of MR fingerprinting (MRF) toward subject motion. METHODS: A novel reconstruction algorithm, MOtion insensitive MRF (MORF), was developed, which uses an iterative reconstruction based retrospective motion correction approach. Each iteration loops through the following steps: pattern recognition, metric based identification of motion corrupted frames, registration based motion estimation, and motion compensated data consistency verification...
May 6, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29703978/time-efficient-whole-brain-coverage-with-mr-fingerprinting-using-slice-interleaved-echo-planar-imaging
#3
Benedikt Rieger, Mehmet Akçakaya, José C Pariente, Sara Llufriu, Eloy Martinez-Heras, Sebastian Weingärtner, Lothar R Schad
Magnetic resonance fingerprinting (MRF) is a promising method for fast simultaneous quantification of multiple tissue parameters. The objective of this study is to improve the coverage of MRF based on echo-planar imaging (MRF-EPI) by using a slice-interleaved acquisition scheme. For this, the MRF-EPI is modified to acquire several slices in a randomized interleaved manner, increasing the effective repetition time of the spoiled gradient echo readout acquisition in each slice. Per-slice matching of the signal-trace to a precomputed dictionary allows the generation of T1 and T2 * maps with integrated B1 + correction...
April 27, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29674609/pressure-induced-superconductivity-bordering-a-charge-density-wave-state-in-nbte-4-with-strong-spin-orbit-coupling
#4
Xiaojun Yang, Yonghui Zhou, Mengmeng Wang, Hua Bai, Xuliang Chen, Chao An, Ying Zhou, Qian Chen, Yupeng Li, Zhen Wang, Jian Chen, Chao Cao, Yuke Li, Yi Zhou, Zhaorong Yang, Zhu-An Xu
Transition-metal chalcogenides host various phases of matter, such as charge-density wave (CDW), superconductors, and topological insulators or semimetals. Superconductivity and its competition with CDW in low-dimensional compounds have attracted much interest and stimulated considerable research. Here we report pressure induced superconductivity in a strong spin-orbit (SO) coupled quasi-one-dimensional (1D) transition-metal chalcogenide NbTe4 , which is a CDW material under ambient pressure. With increasing pressure, the CDW transition temperature is gradually suppressed, and superconducting transition, which is fingerprinted by a steep resistivity drop, emerges at pressures above 12...
April 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29624736/mr-fingerprinting-deep-reconstruction-network-drone
#5
Ouri Cohen, Bo Zhu, Matthew S Rosen
PURPOSE: Demonstrate a novel fast method for reconstruction of multi-dimensional MR fingerprinting (MRF) data using deep learning methods. METHODS: A neural network (NN) is defined using the TensorFlow framework and trained on simulated MRF data computed with the extended phase graph formalism. The NN reconstruction accuracy for noiseless and noisy data is compared to conventional MRF template matching as a function of training data size and is quantified in simulated numerical brain phantom data and International Society for Magnetic Resonance in Medicine/National Institute of Standards and Technology phantom data measured on 1...
April 6, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29545215/estimation-of-perfusion-properties-with-mr-fingerprinting-arterial-spin-labeling
#6
Katherine L Wright, Yun Jiang, Dan Ma, Douglas C Noll, Mark A Griswold, Vikas Gulani, Luis Hernandez-Garcia
In this study, the acquisition of ASL data and quantification of multiple hemodynamic parameters was explored using a Magnetic Resonance Fingerprinting (MRF) approach. A pseudo-continuous ASL labeling scheme was used with pseudo-randomized timings to acquire the MRF ASL data in a 2.5 min acquisition. A large dictionary of MRF ASL signals was generated by combining a wide range of physical and hemodynamic properties with the pseudo-random MRF ASL sequence and a two-compartment model. The acquired signals were matched to the dictionary to provide simultaneous quantification of cerebral blood flow, tissue time-to-peak, cerebral blood volume, arterial time-to-peak, B1 , and T1...
March 12, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29358016/trimage-a-dedicated-trimodality-pet-mr-eeg-imaging-tool-for-schizophrenia
#7
Alberto Del Guerra, Salleh Ahmad, Mihai Avram, Nicola Belcari, Arne Berneking, Laura Biagi, Maria Giuseppina Bisogni, Felix Brandl, Jorge Cabello, Niccolò Camarlinghi, Piergiorgio Cerello, Chang-Hoon Choi, Silvia Coli, Sabrina Colpo, Julien Fleury, Vito Gagliardi, Giuseppe Giraudo, Karsten Heekeren, Wolfram Kawohl, Theodora Kostou, Jean-Luc Lefaucheur, Christoph Lerche, George Loudos, Matteo Morrocchi, Julien Muller, Mona Mustafa, Irene Neuner, Panagiotis Papadimitroulas, Francesco Pennazio, Ravichandran Rajkumar, Cláudia Régio Brambilla, Julien Rivoire, Elena Rota Kops, Jürgen Scheins, Rémy Schimpf, N Jon Shah, Christian Sorg, Giancarlo Sportelli, Michela Tosetti, Riccardo Trinchero, Christine Wyss, Sibylle Ziegler
Simultaneous PET/MR/EEG (Positron Emission Tomography - Magnetic Resonance - Electroencephalography), a new tool for the investigation of neuronal networks in the human brain, is presented here within the framework of the European Union Project TRIMAGE. The trimodal, cost-effective PET/MR/EEG imaging tool makes use of cutting edge technology both in PET and in MR fields. A novel type of magnet (1.5T, non-cryogenic) has been built together with a PET scanner that makes use of the most advanced photodetectors (i...
April 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29243295/extended-phase-graph-formalism-for-systems-with-magnetization-transfer-and-exchange
#8
Shaihan J Malik, Rui Pedro A G Teixeira, Joseph V Hajnal
PURPOSE: An extended phase graph framework (EPG-X) for modeling systems with exchange or magnetization transfer (MT) is proposed. THEORY: EPG-X models coupled two-compartment systems by describing each compartment with separate phase graphs that exchange during evolution periods. There are two variants: EPG-X(BM) for systems governed by the Bloch-McConnell equations, and EPG-X(MT) for the pulsed MT formalism. For the MT case, the "bound" protons have no transverse components, so their phase graph consists of only longitudinal states...
December 15, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29060592/fast-dictionary-generation-and-searching-for-magnetic-resonance-fingerprinting
#9
Jun Xie, Mengye Lyu, Jian Zhang, Edward S Hui, Ed X Wu, Ze Wang
A super-fast dictionary generation and searching (DGS) algorithm was developed for MR parameter quantification using magnetic resonance fingerprinting (MRF). MRF is a new technique for simultaneously quantifying multiple MR parameters using one temporally resolved MR scan. But it has a multiplicative computation complexity, resulting in a big burden of dictionary generating, saving, and retrieving, which can easily be intractable for any state-of-art computers. Based on retrospective analysis of the dictionary matching object function, a multi-scale ZOOM like DGS algorithm, dubbed as MRF-ZOOM, was proposed...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28842384/3d-mr-fingerprinting-with-accelerated-stack-of-spirals-and-hybrid-sliding-window-and-grappa-reconstruction
#10
Congyu Liao, Berkin Bilgic, Mary Kate Manhard, Bo Zhao, Xiaozhi Cao, Jianhui Zhong, Lawrence L Wald, Kawin Setsompop
PURPOSE: Whole-brain high-resolution quantitative imaging is extremely encoding intensive, and its rapid and robust acquisition remains a challenge. Here we present a 3D MR fingerprinting (MRF) acquisition with a hybrid sliding-window (SW) and GRAPPA reconstruction strategy to obtain high-resolution T1 , T2 and proton density (PD) maps with whole brain coverage in a clinically feasible timeframe. METHODS: 3D MRF data were acquired using a highly under-sampled stack-of-spirals trajectory with a steady-state precession (FISP) sequence...
November 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/28831794/simultaneous-en-face-imaging-of-multiple-layers-with-multiple-reference-optical-coherence-tomography
#11
Kai Neuhaus, Seán O'Gorman, Paul M McNamara, Sergey Alexandrov, Josh Hogan, Carol Wilson, Martin J Leahy
A technique based on multiple reference optical coherence tomography (MR-OCT) is proposed for simultaneous imaging at multiple depths. The technique has been validated by imaging a reference sample and a fingerprint in-vivo. The principle of scanning multiple selected layers is shown by imaging a partial fingerprint with 200×200×200 voxels of 3×3×0.5  mm size and obtaining an arbitrary amount of layers merely by digital processing. The spacing among the layers can be adjusted arbitrarily, and the SNR roll-off is shown for three different spacings...
August 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28804918/low-rank-approximation-methods-for-mr-fingerprinting-with-large-scale-dictionaries
#12
Mingrui Yang, Dan Ma, Yun Jiang, Jesse Hamilton, Nicole Seiberlich, Mark A Griswold, Debra McGivney
PURPOSE: This work proposes new low rank approximation approaches with significant memory savings for large scale MR fingerprinting (MRF) problems. THEORY AND METHODS: We introduce a compressed MRF with randomized singular value decomposition method to significantly reduce the memory requirement for calculating a low rank approximation of large sized MRF dictionaries. We further relax this requirement by exploiting the structures of MRF dictionaries in the randomized singular value decomposition space and fitting them to low-degree polynomials to generate high resolution MRF parameter maps...
April 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28796368/regularly-incremented-phase-encoding-mr-fingerprinting-ripe-mrf-for-enhanced-motion-artifact-suppression-in-preclinical-cartesian-mr-fingerprinting
#13
Christian E Anderson, Charlie Y Wang, Yuning Gu, Rebecca Darrah, Mark A Griswold, Xin Yu, Chris A Flask
PURPOSE: The regularly incremented phase encoding-magnetic resonance fingerprinting (RIPE-MRF) method is introduced to limit the sensitivity of preclinical MRF assessments to pulsatile and respiratory motion artifacts. METHODS: As compared to previously reported standard Cartesian-MRF methods (SC-MRF), the proposed RIPE-MRF method uses a modified Cartesian trajectory that varies the acquired phase-encoding line within each dynamic MRF dataset. Phantoms and mice were scanned without gating or triggering on a 7T preclinical MRI scanner using the RIPE-MRF and SC-MRF methods...
April 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28743861/multimodal-fingerprints-of-resting-state-networks-as-assessed-by-simultaneous-trimodal-mr-pet-eeg-imaging
#14
N J Shah, J Arrubla, R Rajkumar, E Farrher, J Mauler, E Rota Kops, L Tellmann, J Scheins, F Boers, J Dammers, P Sripad, C Lerche, K J Langen, H Herzog, I Neuner
Simultaneous MR-PET-EEG (magnetic resonance imaging - positron emission tomography - electroencephalography), a new tool for the investigation of neuronal networks in the human brain, is presented here for the first time. It enables the assessment of molecular metabolic information with high spatial and temporal resolution in a given brain simultaneously. Here, we characterize the brain's default mode network (DMN) in healthy male subjects using multimodal fingerprinting by quantifying energy metabolism via 2- [(18)F]fluoro-2-desoxy-D-glucose PET (FDG-PET), the inhibition - excitation balance of neuronal activation via magnetic resonance spectroscopy (MRS), its functional connectivity via fMRI and its electrophysiological signature via EEG...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28684268/towards-predicting-the-encoding-capability-of-mr-fingerprinting-sequences
#15
K Sommer, T Amthor, M Doneva, P Koken, J Meineke, P Börnert
Sequence optimization and appropriate sequence selection is still an unmet need in magnetic resonance fingerprinting (MRF). The main challenge in MRF sequence design is the lack of an appropriate measure of the sequence's encoding capability. To find such a measure, three different candidates for judging the encoding capability have been investigated: local and global dot-product-based measures judging dictionary entry similarity as well as a Monte Carlo method that evaluates the noise propagation properties of an MRF sequence...
July 3, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28610928/kinetic-and-biophysical-characterization-of-a-lysosomal-%C3%AE-l-fucosidase-from-the-fresh-water-mussel-lamellidens-corrianus
#16
A Venugopal, C Sudheer Kumar, Nadimpalli Siva Kumar, Musti J Swamy
Kinetic and biophysical studies have been carried out on a lysosomal α-l-fucosidase purified from the fresh water mussel, Lamellidens corrianus. The enzyme migrates as a single band in SDS-PAGE as well as native PAGE corresponding to a Mr of 56kDa. Mass spectrometric analysis yielded a molecular mass of 56175.1Da for the enzyme, and peptide mass fingerprinting studies showed that it shares sequence homology with other fucosidases. Zymogram analysis showed that the α-l-fucosidase hydrolyzed 4-methyl umbelliferyl α-l-fucopyranoside...
November 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28433503/mr-fingerprinting-reconstruction-with-kalman-filter
#17
Xiaodi Zhang, Zechen Zhou, Shiyang Chen, Shuo Chen, Rui Li, Xiaoping Hu
Magnetic resonance fingerprinting (MR fingerprinting or MRF) is a newly introduced quantitative magnetic resonance imaging technique, which enables simultaneous multi-parameter mapping in a single acquisition with improved time efficiency. The current MRF reconstruction method is based on dictionary matching, which may be limited by the discrete and finite nature of the dictionary and the computational cost associated with dictionary construction, storage and matching. In this paper, we describe a reconstruction method based on Kalman filter for MRF, which avoids the use of dictionary to obtain continuous MR parameter measurements...
April 19, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28419591/application-of-spin-echoes-in-the-regime-of-weak-dephasing-to-t-1-mapping-of-the-lung
#18
Jakob Assländer, Steffen J Glaser, Jürgen Hennig
PURPOSE: This work presents an approach to mapping the entire lung's proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition. METHODS: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequency-pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting...
February 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28414052/spiral-mr-fingerprinting-at-7t-with-simultaneous-b1-estimation
#19
Guido Buonincontri, Rolf F Schulte, Mirco Cosottini, Michela Tosetti
Magnetic resonance fingerprinting is an efficient, new approach for quantitative imaging with MR. We aimed to extend this technique to cases with B1+ inhomogeneities within the imaging volume. Previous approaches have used abrupt changes in flip angles to estimate the B1+ field simultaneously with T1 and T2, using a Cartesian approach in a small-animal scanner at 4.7T. Here, we evaluated whether a similar approach would be suitable for imaging human brains using spiral readouts with a 7T scanner. We found that our modified scheme could significantly reduce the adverse effects of B1+ inhomogeneities even in extreme cases, reducing both the bias and the variance in T2 estimations by an order of magnitude when compared to literature methods...
April 14, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28412455/effects-of-rf-pulse-profile-and-intra-voxel-phase-dispersion-on-mr-fingerprinting-with-balanced-ssfp-readout
#20
Su-Chin Chiu, Te-Ming Lin, Jyh-Miin Lin, Hsiao-Wen Chung, Cheng-Wen Ko, Martin Büchert, Michael Bock
PURPOSE: To investigate possible errors in T1 and T2 quantification via MR fingerprinting with balanced steady-state free precession readout in the presence of intra-voxel phase dispersion and RF pulse profile imperfections, using computer simulations based on Bloch equations. MATERIALS AND METHODS: A pulse sequence with TR changing in a Perlin noise pattern and a nearly sinusoidal pattern of flip angle following an initial 180-degree inversion pulse was employed...
April 13, 2017: Magnetic Resonance Imaging
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