Congyu Liao, Xiaozhi Cao, Siddharth Srinivasan Iyer, Sophie Schauman, Zihan Zhou, Xiaoqian Yan, Quan Chen, Zhitao Li, Nan Wang, Ting Gong, Zhe Wu, Hongjian He, Jianhui Zhong, Yang Yang, Adam Kerr, Kalanit Grill-Spector, Kawin Setsompop
PURPOSE: This study aims to develop a high-resolution whole-brain multi-parametric quantitative MRI approach for simultaneous mapping of myelin-water fraction (MWF), T1 , T2 , and proton-density (PD), all within a clinically feasible scan time. METHODS: We developed 3D visualization of short transverse relaxation time component (ViSTa)-MRF, which combined ViSTa technique with MR fingerprinting (MRF), to achieve high-fidelity whole-brain MWF and T1 /T2 /PD mapping on a clinical 3T scanner...
December 29, 2023: Magnetic Resonance in Medicine