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https://www.readbyqxmd.com/read/29046995/aquablation-of-the-prostate-for-symptomatic-benign-prostatic-hyperplasia-early-results
#1
REVIEW
Omid Yassaie, Joshua A Silverman, Peter J Gilling
Aquablation is a novel technique for the surgical management of bladder outlet obstruction secondary to benign prostatic hyperplasia. Following first-in-man studies, a multicenter trial was conducted with results now out to 1 year. Aquablation resulted in a mean International Prostate Symptom Score improvement of 16 points (p < 0.01) and a mean maximum urinary flow rate increase from 8.7 to 18.3 ml/s (p < 0.01) at 12 months. Due to the precise prostate mapping, aquablation has also demonstrated favorable sexual and urinary outcomes with no new erectile dysfunction, retrograde ejaculation, or urinary incontinence as often experienced with other techniques...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046467/-clinical-characteristics-of-craniocervical-junction-arteriovenous-fistulas
#2
Michio Nakamura, Tadashi Miyazaki, Natsuki Shinozaki, Masaki Izumi, Takashi Itabashi
OBJECTIVE: Craniocervical junction arteriovenous fistulas(CCJ-AVFs)are extremely rare lesions that may result in both subarachnoid hemorrhage(SAH)and myelopathy. Diagnosis of CCJ-AVF is difficult and may be delayed due to variable clinical features and a spectrum of neuroradiological findings. To elucidate the clinical characteristics of CCJ-AVF, we analyzed the clinical symptoms, neuroimaging findings, and the results of surgical treatment in five patients. RESULTS: Among the five patients, four were diagnosed with dural AVFs, and the remaining patient was diagnosed with radicular AVF...
October 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29044968/a-prospective-randomised-placebo-controlled-study-of-the-impact-of-dutasteride-tamsulosin-combination-therapy-on-sexual-function-domains-in-sexually-active-men-with-lower-urinary-tract-symptoms-luts-secondary-to-benign-prostatic-hyperplasia-bph
#3
Claus G Roehrborn, Michael J Manyak, Juan Manuel Palacios-Moreno, Timothy H Wilson, Erik Pm Roos, Javier Cambronero Santos, Dimitrios Karanastasis, Janet Plastino, Francois Giuliano, Raymond C Rosen
OBJECTIVE: To prospectively assess the impact of the fixed-dose combination of the 5-alpha reductase inhibitor (5ARI), dutasteride 0.5 mg and the alpha-1 blocker, tamsulosin 0.4 mg (DUT-TAM FDC) therapy on sexual function domain scores in sexually active males with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), using the Men's Sexual Health Questionnaire (MSHQ). PATIENTS AND METHODS: This European and Australian double-blind, placebo-controlled, parallel-group study was conducted at 51 centres...
October 16, 2017: BJU International
https://www.readbyqxmd.com/read/29040216/depressive-symptoms-screening-in-postmenopausal-women-with-symptomatic-pelvic-organ-prolapse
#4
Fangfang Ai, Mou Deng, Meng Mao, Tao Xu, Lan Zhu
OBJECTIVE: This study aimed to investigate the prevalence of depressive symptoms in postmenopausal women with symptomatic pelvic organ prolapse (POP) and to identify the factors associated with depressive symptoms in this population. METHODS: We conducted a cross-sectional study involving postmenopausal women with symptomatic POP who visited the Center of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, between July 2016 and March 2017...
October 16, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29034074/recent-advances-in-managing-chronic-prostatitis-chronic-pelvic-pain-syndrome
#5
REVIEW
Jaspreet Sandhu, Hin Yu Vincent Tu
Chronic prostatitis/chronic pelvic pain syndrome is a common disorder seen in men under the age of 50 and has a considerable negative impact on quality of life; it is a complex and difficult condition to treat, owing to its wide symptomatology. In order to effectively treat this condition, the UPOINT system was developed: it allows clinical profiling of a patient's symptoms into six broad categories (urinary symptoms, psychological dysfunction, organ-specific symptoms, infectious causes, neurologic dysfunction, and tenderness of the pelvic floor muscles) to allow individualized and multimodal therapy...
2017: F1000Research
https://www.readbyqxmd.com/read/29031900/resveratrol-improved-detrusor-fibrosis-induced-by-mast-cells-during-progression-of-chronic-prostatitis-in-rats
#6
Yi He, Huizhi Zeng, Yang Yu, Jiashu Zhang, Qi Liu, Bo Yang
To investigate the detrusor fibrosis and urinary dysfunction in chronic prostatitis (CP), and to investigate whether resveratrol can improve the urinary dysfunction and the underlying molecular mechanism. After rat model of CP is established by subcutaneously injecting DPT vaccine, rats are treated with resveratrol. Experiments of bladder pressure and volume test in rats are used to investigate the effect of resveratrol on urinary dysfunction in CP rats. To assess tissue fibrosis, picrosirius red staining is performed...
October 11, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29031313/routes-to-diagnosis-for-men-with-prostate-cancer-men-s-cultural-beliefs-about-how-changes-to-their-bodies-and-symptoms-influence-help-seeking-actions-a-narrative-review-of-the-literature
#7
REVIEW
Michelle King-Okoye, Anne Arber, Sara Faithfull
PURPOSE: To examine the findings of existing studies in relation to men's cultural beliefs about changes to their bodies relevant to prostate cancer and how these affect interpretation of bodily changes and help-seeking actions. METHOD: We undertook a narrative review of studies conducted from 2004 to 2017 in 6 databases that highlighted men's beliefs and help-seeking actions for bodily changes suggestive of prostate cancer. RESULTS: Eighteen (18) studies reflecting men from various ethnicities and nationalities were included...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/29028208/tunable-and-lightweight-on-chip-event-detection-for-implantable-bladder-pressure-monitoring-devices
#8
Robert Karam, Steve J A Majerus, Dennis J Bourbeau, Margot S Damaser, Swarup Bhunia
Lower urinary tract dysfunctions, such as urinary incontinence and overactive bladder, are conditions that greatly affect the quality of life for millions of individuals worldwide. For those with more complex pathophysiologies, diagnosis of these conditions often requires a urodynamics study, providing physicians with a snapshot view of bladder mechanics. Recent advancements in implantable bladder pressure monitors and advanced data analysis techniques have made diagnosis through chronic monitoring a promising prospect...
October 11, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/29023939/comparing-a-novel-hand-held-device-peritron-to-standard-urodynamics-in-measuring-intravesical-pressure
#9
Vladimir A Ruzhynsky, Stephanie Bitzos, Ing Goping, Sidney B Radomski
AIMS: Peritron+ is a new handheld device, which can be attached to a urethral catheter to measure intravesical pressures (Pves). The goal of this study was to assess if Pves recorded by standard urodynamics (UDs) are comparable to those recorded by the Peritron+. METHODS: Patients with voiding dysfunction and an indication for UD underwent measurement of Pves with nonvideo UD and Peritron+. Pves were recorded at volumes of 50, 100, and 200 mL for the supine and sitting positions...
October 11, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29021649/follow-up-urodynamics-in-patients-with-neurogenic-bladder
#10
REVIEW
Sanjay Sinha
INTRODUCTION: Neurogenic bladder patients are at long-term risk of secondary upper urinary tract damage. Symptoms are unreliable and follow-up urodynamics is the only method of ascertaining safety of bladder pressures. This review examines the recommendations, shortcomings and utilization of existing guidelines. The evidence with regard to follow-up urodynamics in different settings relevant to neurogenic bladder is evaluated and an algorithm is proposed. METHODS: A pubmed search was conducted for studies on follow-up urodynamics in patients with neurogenic bladder...
October 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29021382/sustained-activation-of-guanylate-cyclase-a-with-tdt-a-natriuretic-peptide-derivative-exhibits-cardiorenal-protection-in-dahl-salt-sensitive-hypertensive-rats
#11
Shohei Oishi, Naoko Suzuki, Yuri Hasui, Tsuyoshi Homma, Masanori Obana, Takahiro Nagayama, Yasushi Fujio
Heart failure often presents with prognosis-relevant impaired renal function. To investigate whether the chronic activation of guanylate cyclase-A (GC-A) protects both heart and kidney, we examined the effects of TDT, a neprilysin (NEP)-resistant natriuretic peptide (NP) derivative, on cardiac and renal dysfunction in Dahl salt-sensitive hypertensive rats (DS rats). Pretreatment with NEP or NEP inhibitor did not influence GC-A activation by TDT both in vitro and in vivo, resulting in a long-acting profile of TDT compared to native human atrial NP (hANP)...
October 11, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29016579/iodine-and-thyroid-function-status-and-anti-thyroid-peroxidase-antibody-among-pregnant-women-in-eastern-nepal
#12
Lalit Narayan Chaudhary, Saroj Khatiwada, Basanta Gelal, Sharad Gautam, Madhab Lamsal, Hanoon Pokharel, Nirmal Baral
BACKGROUND: Iodine deficiency, thyroid dysfunction and development of thyroid autoimmunity during pregnancy may affect mother and the developing fetus. This study was carried out to find iodine status, thyroid dysfunction and thyroid autoimmunity among pregnant women. METHODS: Ninety two pregnant women from three districts of eastern Nepal (Sunsari, Morang and Jhapa) were enrolled for the study, and urine and blood samples were collected. Urinary iodine concentration (UIC), free thyroxine (free T4), thyroid stimulating hormone (TSH), thyroglobulin and anti-thyroid peroxidase (TPO) antibody levels were estimated...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28991086/bowel-dysfunction-related-to-spina-bifida-keep-it-simple
#13
Charlène Brochard, Benoît Peyronnet, Anne Dariel, Hélène Ménard, Andréa Manunta, Alain Ropert, Michel Neunlist, Guillaume Bouguen, Laurent Siproudhis
BACKGROUND: Although care of urological disorders in spina bifida is well established, there is yet no agreement on a standardized approach to bowel dysfunction in this population. OBJECTIVE: The purpose of this study was to assess bowel dysfunction using validated instruments and the risk factors in adults with spina bifida. DESIGN: A multidisciplinary team prospectively collected patient data, focusing on anorectal and urological symptoms...
November 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28988966/murine-social-stress-results-in-long-lasting-voiding-dysfunction
#14
Stephan Butler, Sandra Luz, Kile McFadden, Joanna Fesi, Christopher Long, Lynn Spruce, Steven Seeholzer, Douglas Canning, Rita Valentino, Stephen Zderic
Repeated exposure to social stress shifts the voiding phenotype in male mice leading to bladder wall remodeling and is associated with increased expression of the stress neuropeptide, corticotropin-releasing factor (CRF) in Barrington's nucleus neurons. In these studies, we set out to determine if the voiding phenotype could recover upon removal from the stressor. Male mice were exposed for 1h daily to an aggressor and the voiding phenotype was assessed at one month followed by randomization to three groups...
October 6, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28988230/urinary-kidney-injury-molecule-1-but-not-urinary-neutrophil-gelatinase-associated-lipocalin-is-increased-after-short-maximal-exercise
#15
Wojciech Wołyniec, Wojciech Ratkowski, Robert Urbański, Maria Bartoszewicz, Danuta Siluk, Zuzanna Wołyniec, Katarzyna Kasprowicz, Katarzyna Zorena, Marcin Renke
BACKGROUND AND AIMS: Urinary neutrophil gelatinase associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are markers of acute kidney injury. The albuminuria is a well-known abnormality after physical exercise. The aim of this study was to investigate changes in uNGAL and uKIM-1 after intensive exercise causing albuminuria. METHODS: The study population consisted of 19 participants (10 males and 9 females). The mean age of participants was 35...
October 7, 2017: Nephron
https://www.readbyqxmd.com/read/28986089/anterior-deflected-urinary-stream
#16
Wisam Abbas, Mark Woodward, Mohamed Sameh Shalaby
We present a case of anterior deflected urinary stream (ADUS) secondary to meatal shelf with no dysfunctional voiding symptoms (DV). The video illustrates the presentation, operative management and literature review. Meatal deformity in girls has been described in association with DV. Hoebeke et al. highlighted the strong correlation between meatal abnormality and non-neurogenic bladder dysfunction in girls. They demonstrated that girls with ADUS had more severe dysfunction on urodynamics. Klijn et al. prospectively evaluated the effect of surgical meatal correction in girls with ADUS...
September 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28976343/urodynamics-before-surgery-for-stress-urinary-incontinence-in-female-patients-an-open-debate
#17
Enrico Finazzi Agro, Valerio Iacovelli, Ester Illiano, Elisabetta Costantini
Currently the debate on the role of urodynamic tests in the preoperative evaluation of female stress urinary incontinence is alight. Although urodynamic investigation (UDI) has been considered mandatory before surgery in all female patients affected by stress urinary incontinence, nowadays international guidelines are more cautious. Literature on this topic has been reviewed in order to clarify the role of UDI before surgery for "complicated" and "uncomplicated" stress urinary incontinence in female patients...
October 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28975420/diagnosis-and-management-of-bladder-bowel-dysfunction-in-children-with-urinary-tract-infections-a-position-statement-from-the-international-children-s-continence-society
#18
Stephen Yang, Michael E Chua, Stuart Bauer, Anne Wright, Per Brandström, Piet Hoebeke, Søren Rittig, Mario De Gennaro, Elizabeth Jackson, Eliane Fonseca, Anka Nieuwhof-Leppink, Paul Austin
BACKGROUND: We present a consensus view from the International Children's Continence Society (ICCS) on the evaluation and management of bladder bowel dysfunction (BBD) in children with urinary tract infection (UTI). The statement aims to highlight the importance of BBD in the development and recurrence of childhood UTI and its management to reduce its associated morbidity and sequelae. METHODS: A systematic literature search was done on PubMed, Embase, and Scopus databases until August 15, 2016...
October 3, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28974905/recent-advances-in-recurrent-urinary-tract-infection-from-pathogenesis-and-biomarkers-to-prevention
#19
REVIEW
Jia-Fong Jhang, Hann-Chorng Kuo
Recurrent urinary tract infection (UTI) might be one of the most common problems in urological clinics. Recent research has revealed novel evidence about recurrent UTI and it should be considered a different disease from the first infection. The pathogenesis of recurrent UTI might include two mechanisms, bacterial factors and deficiencies in host defense. Bacterial survival in the urinary bladder after antibiotic treatment and progression to form intracellular bacterial communities might be the most important bacterial factors...
July 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28974365/predictors-of-outcome-in-children-and-adolescents-with-overactive-bladder-treated-with-parasacral-transcutaneous-electrical-nerve-stimulation
#20
Anselmo Hoffmann, Clara Sampaio, Ana Aparecida Nascimento, Maria Luiza Veiga, Ubirajara Barroso
BACKGROUND: Parasacral transcutaneous electrical nerve stimulation (TENS) has emerged as an effective treatment for overactive bladder (OAB) in view of its high success rates in improving lower urinary tract symptoms and constipation, with no direct side effects. However, the clinical characteristics associated with the outcomes remain to be established. OBJECTIVE: The aim of this study was to evaluate potential predictors of outcome in children with OAB treated using parasacral TENS...
September 8, 2017: Journal of Pediatric Urology
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