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https://www.readbyqxmd.com/read/29454130/abscess-within-a-glioblastoma-mimicking-a-matryoshka-doll
#1
Kislay Kishore, Manish Beniwal, Shilpa Rao, K V L N Rao, Vikas Vazhayil, Dwarkanath Srinivas, Sampath Somanna
BACKGROUND: Abscess co-existing within a brain tumor is a rare entity. Case reports in literature primarily consist of sellar pathology and parenchymal lesions including meningioma, glioma, and metastases. We report a case of glioblastoma with an intra-tumoral abscess in a middle-aged lady with no prior invasive procedure or systemic focus of infection. CASE DESCRIPTION: A 45-year old lady presented with new onset generalized seizures and rapidly progressive left hemiparesis...
February 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29454126/iatrogenic-spondylolisthesis-following-open-lumbar-laminectomy-case-series-and-review-of-the-literature
#2
Seba Ramhmdani, Yuanxuan Xia, Risheng Xu, Thomas Kosztowski, Daniel Sciubba, Timothy Witham, Ali Bydon
OBJECTIVE: The diagnosis and surgical management of post-laminectomy spondylolisthesis in patients without pre-operative instability is presented with a review of relevant literature. METHODS: We reviewed the medical records and radiographic studies of 105 patients who underwent first-time bilateral 1-4 level open laminectomies for degenerative lumbar disease at a single academic institution. Patients who initially presented with listhesis and had additional discectomy or fusion procedures were excluded...
February 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29454118/the-factors-affecting-the-difficulty-of-percutaneous-cylindrical-electrode-placement-for-spinal-cord-stimulation
#3
Kyohei Kin, Takashi Agari, Takao Yasuhara, Yousuke Tomita, Ken Kuwahara, Ittetsu Kin, Michiari Umakoshi, Jun Morimoto, Mihoko Okazaki, Tatsuya Sasaki, Isao Date
OBJECTIVE: Optimal placement of electrodes is important for spinal cord stimulation. Unfortunately, factors affecting the difficulty of percutaneous electrode placement are not well known. In this study, we retrospectively evaluated the factors affecting the difficulty of percutaneous electrode placement. METHODS: The authors performed a retrospective analysis of 90 consecutive procedures of percutaneous cylindrical electrodes implantation at the first author's institution...
February 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29453515/micro-fragmented-adipose-tissue-injection-for-the-treatment-of-complex-anal-fistula-a-pilot-study-accessing-safety-and-feasibility
#4
G Naldini, A Sturiale, B Fabiani, I Giani, C Menconi
BACKGROUND: The aim of the present study was to evaluate the safety and efficacy of autologous, micro-fragmented and minimally manipulated adipose tissue injection associated closure of the internal opening in promoting healing of complex anal fistula. METHODS: A pilot study was conducted on patients referred to our center with anal fistula, from April 2015-December 2016. Inclusion criteria were age over 16 years old and a diagnosis of complex anal fistula according to the American Gastroenterological Association classification The patients were divided into 2 groups; the "first time group" (Group I) in which micro-fragmented adipose tissue injection with closure of the internal opening was the first sphincter-saving procedure, and the "recurrent group" (Group II) consisting of patients who had failed prior sphincter-saving procedures...
February 16, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29453242/single-subject-spm-fdg-pet-patterns-predict-risk-of-dementia-progression-in-parkinson-disease
#5
Andrea Pilotto, Enrico Premi, Silvia Paola Caminiti, Luca Presotto, Rosanna Turrone, Antonella Alberici, Barbara Paghera, Barbara Borroni, Alessandro Padovani, Daniela Perani
OBJECTIVE: To evaluate the statistical parametric mapping (SPM) procedure for fluorodeoxyglucose (FDG)-PET imaging as a possible single-subject marker of progression to dementia in Parkinson disease (PD). METHODS: Fifty-four consecutive patients with PD without dementia (age at onset of 59.9 ± 10.1 years, disease duration of 5.3 ± 3.4 years) entered the study. The patients underwent an extensive motor and cognitive assessment and a single-subject FDG-PET SPM evaluation at baseline...
February 16, 2018: Neurology
https://www.readbyqxmd.com/read/29452832/delayed-endovascular-aortic-repair-is-associated-with-reduced-in-hospital-mortality-in-patients-with-blunt-thoracic-aortic-injury
#6
Christina L Marcaccio, Ryan P Dumas, Yanlan Huang, Wei Yang, Grace J Wang, Daniel N Holena
OBJECTIVE: The traditional approach to stable blunt thoracic aortic injury (BTAI) endorsed by the Society for Vascular Surgery is early (<24 hours) thoracic endovascular aortic repair (TEVAR). Recently, some studies have shown improved mortality in stable BTAI patients repaired in a delayed manner (≥24 hours). However, the indications for use of delayed TEVAR for BTAI are not well characterized, and its overall impact on the patient's survival remains poorly understood. We sought to determine whether delayed TEVAR is associated with a decrease in mortality compared with early TEVAR in this population...
February 13, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29452729/postoperative-pneumonia-among-patients-with-and-without-copd-in-spain-from-2001-to-2015
#7
Javier de Miguel-Díez, Ana López-de-Andrés, Valentín Hernández-Barrera, Isabel Jiménez-Trujillo, Manuel Méndez-Bailón, José María de Miguel-Yanes, Rodrigo Jiménez-García
BACKGROUND: To describe and compare incidence, characteristics and outcomes of postoperative pneumonia among patients with or without COPD. METHODS: We included hospitalized patients aged ≥40 years whose medical diagnosis included pneumonia and ventilator-associated pneumonia in the secondary's diagnosis field and who were discharged from Spanish hospitals from 2001 to 2015. Irrespectively of the position at the procedures coding list, we retrieved data about the type of surgical procedures using the enhanced ICD-9-CM codes...
February 13, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29452722/traumatic-lingual-hematoma-resulting-in-bilateral-temporal-mandibular-joint-dislocations
#8
Dhara P Amin, Michael N Cooper, Kim I Newton
BACKGROUND: Lingual hematoma (LH) is a relatively uncommon entity seen after both medical and traumatic etiologies. Regardless of the cause, the feared complication is acute airway obstruction. CASE REPORT: Our case involves a 39-year-old man who presented to the Emergency Department via emergency medical services with an enlarging LH after an unwitnessed fall, suspected to be an alcohol withdrawal seizure. The bleeding was likely exacerbated by previously undiagnosed thrombocytopenia...
February 13, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29452620/pathogen-specific-bacterial-imaging-in-nuclear-medicine
#9
REVIEW
Alvaro A Ordonez, Sanjay K Jain
When serious infections are suspected, patients are often treated empirically with broad-spectrum antibiotics while awaiting results that provide information on the bacterial class and species causing the infection, as well as drug susceptibilities. For deep-seated infections, these traditional diagnostic techniques often rely on tissue biopsies to obtain clinical samples which can be expensive, dangerous, and has the potential of sampling bias. Moreover, these procedures and results can take several days and may not always provide reliable information...
March 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29452618/radionuclide-imaging-of-infection-and-inflammation-in-children-a-review
#10
REVIEW
Marguerite T Parisi, Jeffrey P Otjen, A Luana Stanescu, Barry L Shulkin
With the exception of radiolabeled monoclonal antibodies, antibody fragments and radiolabeled peptides which have seen little application in the pediatric population, the nuclear medicine imaging procedures used in the evaluation of infection and inflammation are the same for both adults and children. These procedures include (1) either a two- or a three-phase bone scan using technetium-99m methylene diphosphonate; (2) Gallium 67-citrate; (3) in vitro radiolabeled white blood cell imaging (using 111 Indium-oxine or 99m Technetium hexamethyl-propylene-amine-oxime-labeled white blood cells); and (4) hybrid imaging with 18 F-FDG...
March 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29452617/imaging-of-spondylodiscitis
#11
REVIEW
Meera Raghavan, Elena Lazzeri, Christopher J Palestro
Spondylodiscitis is an infection of the vertebral body or disc and may also involve the epidural space, posterior elements, and paraspinal soft tissues. It is a cause of morbidity and mortality, and warrants early diagnosis and prompt treatment. Diagnosis can be difficult because of nonspecific signs and symptoms. Magnetic resonance imaging is sensitive and specific and is the imaging modality of choice for spondylodiscitis. Gadolinium contrast can show the extent of soft tissue and bone phlegmon and abscess...
March 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29452615/fever-of-unknown-origin-the-value-of-fdg-pet-ct
#12
REVIEW
Ilse J E Kouijzer, Catharina M Mulders-Manders, Chantal P Bleeker-Rovers, Wim J G Oyen
Fever of unknown origin (FUO) is commonly defined as fever higher than 38.3°C on several occasions during at least 3 weeks with uncertain diagnosis after a number of obligatory investigations. The differential diagnosis of FUO can be subdivided in four categories: infections, malignancies, noninfectious inflammatory diseases, and miscellaneous causes. In most cases of FUO, there is an uncommon presentation of a common disease. FDG-PET/CT is a sensitive diagnostic technique for the evaluation of FUO by facilitating anatomical localization of focally increased FDG uptake, thereby guiding further diagnostic tests to achieve a final diagnosis...
March 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29452105/label-free-electrochemical-aptasensor-for-detection-of-alpha-fetoprotein-based-on-afp-aptamer-and-thionin-reduced-graphene-oxide-gold-nanoparticles
#13
Guiyin Li, Shanshan Li, Zhihong Wang, Yewei Xue, Chenyang Dong, Junxiang Zeng, Yong Huang, Jintao Liang, Zhide Zhou
Sensitive and accurate detection of tumor markers is critical to early diagnosis, point-of-care and portable medical supervision. Alpha fetoprotein (AFP) is an important clinical tumor marker for hepatocellular carcinoma (HCC), and the concentration of AFP in human serum is related to the stage of HCC. In this paper, a label-free electrochemical aptasensor for AFP detection was fabricated using AFP-aptamer as the recognition molecule and thionin/reduced graphene oxide/gold nanoparticles (TH/RGO/Au NPs) as the sensor platform...
February 13, 2018: Analytical Biochemistry
https://www.readbyqxmd.com/read/29451859/harmonization-of-pcr-based-detection-of-intestinal-pathogens-experiences-from-the-dutch-external-quality-assessment-scheme-on-molecular-diagnosis-of-protozoa-in-stool-samples
#14
Theo A Schuurs, Rob Koelewijn, Eric A T Brienen, Titia Kortbeek, Theo G Mank, Bert Mulder, Foekje F Stelma, Lisette van Lieshout, Jaap J van Hellemond
BACKGROUND: Real-time PCR methods are increasingly used in routine patient care settings not only to determine the presence or absence of pathogens in patient materials, but also to obtain semiquantitative results to estimate the pathogen load. However, it is so far unknown how well these methods are harmonized among different laboratories. METHODS: Sets of stool samples were distributed three to four times per year to ca. 25-40 participating laboratories within the European Union as part of an external quality assessment scheme (EQAS) for the detection of gastrointestinal protozoa...
February 16, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29451656/posterior-fossa-decompression-with-duraplasty-in-chiari-surgery-a-technical-note
#15
Marcelo Ferreira Sabba, Beatriz Souza Renor, Enrico Ghizoni, Helder Tedeschi, Andrei Fernandes Joaquim
Chiari malformation (CM) is the most common and prevalent symptomatic congenital craniocervical malformation. Radiological diagnosis is established when the cerebellar tonsils are located 5 mm or more below the level of the foramen magnum on magnetic resonance imaging (MRI). Surgical treatment is indicated whenever there is symptomatic tonsillar herniation or syringomyelia/hydrocephalus. The main surgical treatment for CM without craniocervical instability (such as atlantoaxial luxation) is posterior fossa decompression, with or without duraplasty...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29451590/by-the-book-adhd-prevalence-in-medical-students-varies-with-analogous-methods-of-addressing-dsm-items
#16
Paulo Mattos, Bruno P Nazar, Rosemary Tannock
OBJECTIVE: The marked increase in the prevalence of attention-deficit/hyperactivity disorder (ADHD) among university students gives rise to questions about how best to diagnose in this setting. The aim of the present study was to calculate ADHD prevalence in a large non-clinical sample of medical students using a stepwise design and to determine whether ADHD diagnosis varies if interviewees use additional probing procedures to obtain examples of positive DSM items. METHODS: A total of 726 students were screened with the Adult Self-Report Scale (ASRS) and invited for an interview with the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) adapted for adults...
February 15, 2018: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29451437/do-intraoperative-radiographs-predict-final-lumbar-sagittal-alignment-following-single-level-transforaminal-lumbar-interbody-fusion
#17
Khalid M I Salem, Aditya P Eranki, Scott Paquette, Michael Boyd, John Street, Brian K Kwon, Charles G Fisher, Marcel F Dvorak
OBJECTIVE The study aimed to determine if the intraoperative segmental lordosis (as calculated on a cross-table lateral radiograph following a single-level transforaminal lumbar interbody fusion [TLIF] for degenerative spondylolisthesis/low-grade isthmic spondylolisthesis) is maintained at discharge and at 6 months postsurgery. METHODS The authors reviewed images and medical records of patients ≥ 16 years of age with a diagnosis of an isolated single-level, low-grade spondylolisthesis (degenerative or isthmic) with symptomatic spinal stenosis treated between January 2008 and April 2014...
February 16, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29451167/a-multicenter-comparative-trial-of-a-novel-eus-guided-core-biopsy-needle-sharkcore-%C3%A2-with-the-22-gauge-needle-in-patients-with-solid-pancreatic-mass-lesions
#18
Mariam Naveed, Ali A Siddiqui, Thomas E Kowalski, David E Loren, Ammara Khalid, Ayesha Soomro, Syed M Mazhar, Joseph Yoo, Raza Hasan, Silpa Yalamanchili, Nicholas Tarangelo, Linda J Taylor, Douglas G Adler
Background and Objectives: The ability to obtain adequate tissue of solid pancreatic lesions by EUS-guided remains a challenge. The aim of this study was to compare the performance characteristics and safety of EUS-FNA for evaluating solid pancreatic lesions using the standard 22-gauge needle versus a novel EUS biopsy needle. Methods: This was a multicenter retrospective study of EUS-guided sampling of solid pancreatic lesions between 2009 and 2015. Patients underwent EUS-guided sampling with a 22-gauge SharkCore (SC) needle or a standard 22-gauge FNA needle...
January 2018: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29451124/copper-oxide-loaded-plga-nanospheres-towards-a-multifunctional-nanoscale-platform-for-ultrasound-based-imaging-and-therapy
#19
Or Perlman, Iris S Weitz, Sarit Sivan, Hiba Abu-Khalla, Madeleine Benguigui, Yuval Shaked, Haim Azhari
Copper oxide nanoparticles (CuO-NPs) are increasingly investigated for diagnostic and therapeutic purposes. Recent work have demonstrated their anticancer potential as well as contrast agent capabilities for magnetic resonance imaging (MRI) and through-transmission ultrasound. However, no capabilities of CuO-NPS were demonstrated using conventional ultrasound systems, which, unlike the formers, are widely deployed in the clinic. Furthermore, in spite of their potential as multifunctional nano-based materials for diagnosis and therapy, CuO-NPs were delayed from further clinical translation due to their inherent toxicity...
February 16, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29451037/esophageal-hiatal-hernia-risk-diagnosis-and-management
#20
Hai-Xiang Yu, Chun-Shan Han, Jin-Ru Xue, Zhi-Feng Han, Hua Xin
Esophageal hiatal hernia involves abnormal abdominal entry into thoracic cavity. It is classified based on orientation between esophageal junction and diaphragm. Sliding hiatal hernia (Type-I) comprises the most frequent category, emanating from right crus of diaphragm. Type-II esophageal hernia engages both left and right muscular crura. Type-III and IV additionally include the left crus. Age and increased body mass index are key risk factors, and congenital skeletal aberrations trigger pathogenesis through intestinal malrotations...
February 16, 2018: Expert Review of Gastroenterology & Hepatology
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