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quality of life glaucoma

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https://www.readbyqxmd.com/read/28516509/the-incidence-and-predictors-of-depressive-and-anxiety-symptoms-in-older-adults-with-vision-impairment-a-longitudinal-prospective-cohort-study
#1
Thomas J Heesterbeek, Hilde P A van der Aa, Ger H M B van Rens, Johannes W R Twisk, Ruth M A van Nispen
PURPOSE: Depression and anxiety are highly prevalent in older adults with vision impairment. Because symptoms of depression and anxiety appear to fluctuate, it is important to identify patients who are at risk of developing these symptoms for early diagnosis and treatment. Therefore, the aim of this study was to determine the incidence of subthreshold depression and anxiety, and to investigate predictors of developing symptoms of depression and anxiety in older adults with vision impairment who had no subthreshold depression or anxiety at baseline...
May 18, 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28499445/vision-related-quality-of-life-following-glaucoma-filtration-surgery
#2
Kazuyuki Hirooka, Eri Nitta, Kaori Ukegawa, Akitaka Tsujikawa
BACKGROUND: To evaluate vision-related quality of life (VR-QOL) following glaucoma filtration surgery. METHODS: A total of 103 glaucoma patients scheduled to undergo glaucoma filtration surgery. Prior to and at three months after glaucoma filtration surgery, trabeculectomy or EX-PRESS, all patients completed the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25). A total of 48 patients underwent combined cataract and filtration surgery. The clinical data collected pre- and postoperatively included best-corrected visual acuity (BCVA) and intraocular pressure (IOP)...
May 12, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28480834/the-conjunctiva-associated-lymphoid-tissue-in-chronic-ocular-surface-diseases
#3
Rodolfo Mastropasqua, Luca Agnifili, Vincenzo Fasanella, Mario Nubile, Agbeanda A Gnama, Gennaro Falconio, Paolo Perri, Silvio Di Staso, Cesare Mariotti
Ocular surface diseases (OSDs) represent a widely investigated field of research given their growing incidence and the negative impact on quality of life. During OSDs, cytokines generated by damaged epithelia trigger and deregulate the lymphoid cells composing the eye-associated lymphoid tissues, inducing an immune-mediated chronic inflammation that amplifies and propagates the disease during time. The conjunctiva-associated lymphoid tissue (CALT), given its particular position that permits immune cells covering the cornea, might play a crucial role in the development of OSDs...
May 8, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28475699/biomarkers-and-surrogate-endpoints-lessons-learned-from-glaucoma
#4
Felipe A Medeiros
With the recent progress in imaging technologies for assessment of structural damage in glaucoma, a debate has emerged on whether these measurements can be used as valid surrogate endpoints in clinical trials evaluating new therapies for the disease. A discussion of surrogates should be grounded on knowledge acquired from their use in other areas of medicine as well as regulatory requirements. This article reviews the conditions for valid surrogacy in the context of glaucoma clinical trials and critically evaluates the role of biomarkers such as IOP and imaging measurements as potential surrogates for clinically relevant outcomes...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28475698/the-growing-need-for-validated-biomarkers-and-endpoints-for-dry-eye-clinical-research
#5
Neeta S Roy, Yi Wei, Eric Kuklinski, Penny A Asbell
Purpose: Biomarkers with minimally invasive and reproducible objective metrics provide the key to future paradigm shifts in understanding of the underlying causes of dry eye disease (DED) and approaches to treatment of DED. We review biomarkers and their validity in providing objective metrics for DED clinical research and patient care. Methods: The English-language literature in PubMed primarily over the last decade was surveyed for studies related to identification of biomarkers of DED: (1) inflammation, (2) point-of-care, (3) ocular imaging, and (4) genetics...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28469940/gradually-then-suddenly-decline-in-vision-related-quality-of-life-as-glaucoma-worsens
#6
Lee Jones, Susan R Bryan, David P Crabb
Purpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range of VF loss identified from a UK hospital-based glaucoma service database. Trends were assessed in a composite score from NEI VFQ-25 against better-eye mean deviation (BEMD) using linear regression and a spline-fitting method that can highlight where a monotonic relationship may have different stages...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28457055/short-term-efficacy-of-cbd-enriched-hemp-oil-in-girls-with-dysautonomic-syndrome-after-human-papillomavirus-vaccination
#7
Beniamino Palmieri, Carmen Laurino, Maria Vadalà
BACKGROUND: Cannabidiol (CBD)-based treatments for several diseases, including Tourette's syndrome, multiple sclerosis, epilepsy, movement disorders and glaucoma, are proving to be beneficial and the scientific clinical background of the drug is continuously evolving. OBJECTIVES: To investigate the short-term effect of CBD-enriched hemp oil for relieving symptoms and improving the life quality (QOL) in young girls with adverse drug effects (ADRs) following human papillomavirus (HPV) vaccine...
February 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28442683/achievements-and-limits-of-current-medical-therapy-of-glaucoma
#8
Pelagia Kalouda, Christina Keskini, Eleftherios Anastasopoulos, Fotis Topouzis
Prescribing medical therapy for the treatment of glaucoma can be a complex process since many parameters should be taken into consideration regarding its achievements and limits. Today, a variety of options, including multiple drug classes and multiple agents within classes, are available to the clinician, but caution should be given to their side effects and contraindications. Glaucoma patients with preexisting ocular surface disease should be treated with caution, and preferably with preservative-free formulations, as there is an increased risk for symptom deterioration...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28408039/binocular-measures-of-visual-acuity-and-visual-field-versus-binocular-approximations
#9
David C Musch, Leslie M Niziol, Brenda W Gillespie, Paul R Lichter, Nancy K Janz
PURPOSE: To assess the relationship of binocular visual function tests with binocular approximations using data from the Collaborative Initial Glaucoma Treatment Study (CIGTS). DESIGN: Case series based on existing data from a clinical trial. PARTICIPANTS: Six hundred seven patients with newly diagnosed open-angle glaucoma from the CIGTS. METHODS: Monocular visual field (VF) and visual acuity (VA) tests were performed at baseline and every 6 months thereafter...
April 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28385300/quality-of-life-and-functional-vision-in-children-with-glaucoma
#10
Annegret Dahlmann-Noor, Vijay Tailor, Catey Bunce, Yassir Abou-Rayyah, Gillian Adams, John Brookes, Peng T Khaw, Maria Papadopoulos
PURPOSE: To evaluate the effect of glaucoma on functional vision and on vision-related (VR) and health-related (HR) quality of life (QoL) in children up to 16 years of age. DESIGN: Cross-sectional observational study. PARTICIPANTS: One hundred nineteen children 2 to 16 years of age (mean age, 9.4 years; standard deviation [SD], 4.56 years) with glaucoma and their parents. METHODS: Completion of 3 validated instruments for children to assess (1) functional visual ability (FVA) with the Cardiff Visual Ability Questionnaire for Children (CVAQC), (2) VR QoL with the Impact of Vision Impairment for Children (IVI-C), and (3) HR QoL with the Pediatric Quality of Life Inventory (PedsQL) version 4...
April 3, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28322732/glaucoma-patient-reported-concerns-and-associated-factors
#11
Rachel S Mogil, Andrew Tirsi, Jung Min Lee, Celso Tello, Sung Chul Park
PURPOSE: To assess the character and degree of concerns of glaucoma patients and identify demographic/clinical factors affecting the concerns. DESIGN: Prospective cross-sectional study. METHODS: A questionnaire that addressed patients' concerns was administered to consecutive glaucoma patients. Severity of concern was scored with a scale of 0 to 5 in order of increasing severity. Age, gender, intraocular pressure, visual field (VF) mean deviation (MD), number of anti-glaucoma medications, history of glaucoma surgery, and employment status were recorded...
March 16, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28318724/-preliminary-study-of-the-quality-of-life-of-glaucoma-patients-in-the-district-of-sousse-tunisia-sociodemographic-and-clinical-associations
#12
L Knani, F Gatfaoui, A Mahjoub, M Ghorbel, H Mahjoub, F Ben Hadj Hamida
PURPOSE: To assess the vision-specific quality-of-life (VS-QoL) of glaucoma patients followed at Farhat Hached university hospital, Sousse-Tunisia, and identify clinical and sociodemographic factors potentially affecting it. METHODS: This was a cross-sectional study enrolling one-hundred twenty patients followed for primary open angle glaucoma (POAG). All the patients successfully responded to the Arabic version of the National Eye Institute Visual Function Questionnaire 25 (NEI-VFQ 25)...
March 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28293433/eye-tracking-as-a-tool-to-evaluate-functional-ability-in-everyday-tasks-in-glaucoma
#13
REVIEW
Enkelejda Kasneci, Alex A Black, Joanne M Wood
To date, few studies have investigated the eye movement patterns of individuals with glaucoma while they undertake everyday tasks in real-world settings. While some of these studies have reported possible compensatory gaze patterns in those with glaucoma who demonstrated good task performance despite their visual field loss, little is known about the complex interaction between field loss and visual scanning strategies and the impact on task performance and, consequently, on quality of life. We review existing approaches that have quantified the effect of glaucomatous visual field defects on the ability to undertake everyday activities through the use of eye movement analysis...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28284903/ocular-and-visual-disorders-in-parkinson-s-disease-common-but-frequently-overlooked
#14
REVIEW
Merel S Ekker, Sabine Janssen, Klaus Seppi, Werner Poewe, Nienke M de Vries, Thomas Theelen, Jorik Nonnekes, Bastiaan R Bloem
Patients with Parkinson's disease (PD) often compensate for their motor deficits by guiding their movements visually. A wide range of ocular and visual disorders threatens the patients' ability to benefit optimally from visual feedback. These disorders are common in patients with PD, yet they have received little attention in both research and clinical practice, leading to unnecessary - but possibly treatable - disability. Based on a literature search covering 50 years, we review the range of ocular and visual disorders in patients with PD, and classify these according to anatomical structures of the visual pathway...
February 21, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28280297/does-the-world-health-organization-criterion-adequately-define-glaucoma-blindness
#15
P Mokhles, Jsag Schouten, Hjm Beckers, Cab Webers
PURPOSE: Blindness in glaucoma is difficult to assess with merely the use of the current World Health Organization (WHO) definition (a visual field restricted to 10° in a radius around central fixation), as this criterion does not cover other types of visual field loss that are encountered in clinical practice and also depict blindness. In this study, a 5-point ordinal scale was developed for the assessment of common visual field defect patterns, with the purpose of comparing blindness as outcome to the findings with the WHO criterion when applied to the same visual fields...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28260356/-focus-on-popular-science-education-of-glaucoma-and-reduce-glaucomatous-low-vision-and-blindness
#16
X H Sun
The prevention of blindness caused by glaucoma is a difficult task. In order to accomplish the task better, we need the participation of whole society and popularize relevant medical knowledge. Popular science and related knowledge of glaucoma are needed to the people especially for high risk population. If people know glaucoma better and actively join the screening of glaucoma, we can find and diagnose glaucoma earlier, avoid late treatment and reduce the glaucomatous visual function impairment. For patients who had been diagnosed with glaucoma, they should aware and accept new medical concept and technique through systemic popular science education...
February 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28251091/a-cross-sectional-study-on-compliance-with-topical-glaucoma-medication-and-its-associated-socioeconomic-burden-for-a-chinese-population
#17
Man-Hin Lui, Jason Chun Ho Lam, Yi Lee Kwong, Tak Siu Wong, Pak Long Cheung, Sherri Shun Yan Lai, Pak Lun Yuen, Wai Yiu Lam, Ho Yan Chan, Yiu Fai Wong, Jimmy Shiu Ming Lai, Kendrick Co Shih
AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment. METHODS: This was a retrospective cross-sectional study. Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication, attitude towards glaucoma and therapy and vision related quality of life. Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28218404/topical-medication-instillation-techniques-for-glaucoma
#18
REVIEW
Li Xu, Xuemei Wang, Meijing Wu
BACKGROUND: Glaucoma is a leading cause of irreversible blindness worldwide and the second most common cause of blindness after cataracts. The primary treatment for glaucoma aims to lower intraocular pressure (IOP) with the use of topical medicines. Topical medication instillation techniques, such as eyelid closure and nasolacrimal occlusion when instilling drops, have been proposed as potential methods to increase ocular absorption and decrease systemic absorption of the drops. OBJECTIVES: To investigate the effectiveness of topical medication instillation techniques compared with usual care or another method of instillation of topical medication in the management of glaucoma or ocular hypertension...
February 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28186941/preference-based-disease-specific-health-related-quality-of-life-instrument-for-glaucoma-a-mixed-methods-study-protocol
#19
Sergei Muratov, Dominik W Podbielski, Susan M Jack, Iqbal Ike K Ahmed, Levine A H Mitchell, Monika Baltaziak, Feng Xie
INTRODUCTION: A primary objective of healthcare services is to improve patients' health and health-related quality of life (HRQoL). Glaucoma, which affects a substantial proportion of the world population, has a significant detrimental impact on HRQoL. Although there are a number of glaucoma-specific questionnaires to measure HRQoL, none is preference-based which prevent them from being used in health economic evaluation. The proposed study is aimed to develop a preference-based instrument that is capable of capturing important effects specific to glaucoma and treatments on HRQoL and is scored based on the patients' preferences...
November 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/28161049/quality-of-life-in-the-tube-versus-trabeculectomy-study
#20
RANDOMIZED CONTROLLED TRIAL
Aachal Kotecha, William J Feuer, Keith Barton, Steven J Gedde
PURPOSE: To report the vision-specific quality-of-life (QoL) outcomes in the Tube Versus Trabeculectomy (TVT) Study. DESIGN: Multicenter randomized clinical trial. METHODS: Setting: Seventeen clinical centers. STUDY POPULATION: Patients 18-85 years of age with medically uncontrolled glaucoma who had previous cataract and/or glaucoma surgery. INTERVENTIONS: Tube shunt (350-mm(2) Baerveldt glaucoma implant) or trabeculectomy with MMC...
April 2017: American Journal of Ophthalmology
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