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Pharmacy economics

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https://www.readbyqxmd.com/read/29344376/effectiveness-of-pharmacist-s-intervention-in-the-management-of-cardiovascular-diseases
#1
REVIEW
Stefano Omboni, Marina Caserini
The pharmacist may play a relevant role in primary and secondary prevention of cardiovascular diseases, mainly through patient education and counselling, drug safety management, medication review, monitoring and reconciliation, detection and control of specific cardiovascular risk factors (eg, blood pressure, blood glucose, serum lipids) and clinical outcomes. Systematic reviews of randomised controlled and observational studies have documented an improved control of hypertension, dyslipidaemia or diabetes, smoking cessation and reduced hospitalisation in patients with heart failure, following a pharmacist's intervention...
2018: Open Heart
https://www.readbyqxmd.com/read/29337604/the-current-status-of-outcomes-based-contracting-for-manufacturers-and-payers-an-amcp-membership-survey
#2
Amy Duhig, Soumi Saha, Stacie Smith, Stew Kaufman, Janet Hughes
BACKGROUND: As the United States health care system shifts from traditional volume-based payments to value-based payments, outcomes-based contracts (OBCs) are gaining popularity among payers and manufacturers as a mechanism for the shift toward value. Under this model, stakeholders hope to align drug payment and value to real-world performance metrics (e.g., biomarkers and health care resource utilization). OBJECTIVE: To understand the experiences, perceptions, and needs of payers and manufacturers related to OBCs...
December 22, 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29336841/economic-impact-of-the-new-oral-treatments-for-multiple-sclerosis
#3
L Álvarez Ayuso, B Rodríguez Marrodán, M R Blasco Quílez, J A García-Merino, A Sánchez Guerrero
INTRODUCTION: Multiple sclerosis (MS) is a chronic disease affecting the central nervous system and is characterised by inflammation, demyelination, gliosis, and axonal damage. The introduction of dimethyl fumarate and teriflunomide has led to an increase in the number of alternative first-line therapies for MS. The objective of this study was to evaluate the economic impact of the incorporation of new oral therapies at the reference unit (CSUR) at Hospital Universitario Puerta de Hierro Majadahonda...
January 11, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/29325000/alcohol-tobacco-and-health-care-costs-a-population-wide-cohort-study-n-606-947-patients-of-current-drinkers-based-on-medical-and-administrative-health-records-from-catalonia
#4
Laia Miquel, Jürgen Rehm, Kevin D Shield, Emili Vela, Montserrat Bustins, Lidia Segura, Joan Colom, Peter Anderson, Antoni Gual
Background: Most cost of illness studies are based on models where information on exposure is combined with risk information from meta-analyses, and the resulting attributable fractions are applied to the number of cases. Methods: This study presents data on alcohol and tobacco use for 2011 and 2012 obtained from a routine medical practice in Catalonia of 606 947 patients, 18 years of age and older, as compared with health care costs for 2013 (all costs from the public health care system: primary health care visits, hospital admissions, laboratory and medical tests, outpatient visits to specialists, emergency department visits and pharmacy expenses)...
January 8, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29320915/healthcare-utilization-and-costs-associated-with-treatment-for-opioid-dependence
#5
Ankit Shah, Margaret Duncan, Nipun Atreja, Kei Sing Tai, Mugdha Gore
OBJECTIVE: Opioid use disorder (OUD) can be managed with medication assisted therapy (MAT) (methadone [MET], buprenorphine [BUP], or extended-release naltrexone [XR-NTX]) or counseling alone (non-pharmacological therapy [NPT]). The objective of this study was to evaluate healthcare resource utilization and costs associated with XR-NTX compared with alternative treatments for opioid dependence. METHODS: Adults with a diagnosis of opioid dependence who initiated treatment with XR-NTX, BUP, MET, or NPT between January 1, 2011 and December 31, 2014 were identified in the Truven Health MarketScan Commercial administrative claims database...
January 10, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29315859/medical-and-economic-factors-influencing-generic-drug-use-in-the-japanese-public-health-system-influencing-factors-in-different-populations
#6
Tomoya Tachi, Kosuke Saito, Hiroki Esaki, Yuta Kanematsu, Aki Yoshida, Ikuto Sugita, Yoshihiro Noguchi, Teppei Makino, Michi Umeda, Masahiro Yasuda, Takashi Mizui, Chitoshi Goto, Hitomi Teramachi
Factors influencing generic drug use must be considered when new drug policies are established and initiatives are implemented to promote generic drug use. This study was conducted to elucidate medical and economic factors that influence generic drug use in the Japanese public health system by evaluating the degree of generic drug use via a multivariate analysis. We conducted a retrospective study of medications administered to inpatients at Gifu Municipal Hospital (Japan) from November 1 to 14, 2014. Details of inpatients (age, sex, and type of medical insurance) and the drugs administered (prescribing institution, dispensing pharmacy, price, and class) were assessed...
January 8, 2018: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29297705/use-of-the-thermocool-smarttouch-catheter-for-ablation-of-atrial-fibrillation-the-relationship-between-hospital-procedure-volume-readmissions-and-economic-outcomes
#7
Andrea Barnow, Laura Goldstein, Iftekhar Kalsekar, Ray Liao, Rahul Khanna
OBJECTIVE: The purpose of this study was to examine the relationship between hospital volume of prior THERMOCOOL SMARTTOUCH Catheter use and health and economic outcomes among hospitalized patients with atrial fibrillation (AF) undergoing ablation using this device. MATERIALS AND METHODS: Patients aged ≥18 years with a primary diagnosis of AF undergoing ablation treatment using the THERMOCOOL SMARTTOUCH Catheter between January 2014 and June 2016 were identified from the Premier hospital database with the first date of such procedure being defined as the index date...
January 3, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29297655/the-emerging-role-of-gammacore-in-the-management-of-cluster-headache-expert-panel-recommendations
#8
Stephen D Silberstein, Anne H Calhoun, Christina Treppendahl, David W Dodick, Alan M Rapoport, Avinash Mamidi, Peter Vargas, Thomas H Ebert, Stewart J Tepper
A panel of 9 experts, including neurologists, other headache specialists, and medical and pharmacy directors, from 4 health plans (1 integrated delivery network and 3 plans with commercial, Medicare, and Medicaid lines of business), convened to discuss cluster headache (CH). Topics covered included the current treatment landscape, treatment challenges, economic impact of disease, and gaps in care for patients with CH. One major challenge in the management of CH is that it is underrecognized and frequently misdiagnosed, leading to delays in and suboptimal treatment for patients who suffer from this painful and disabling condition...
November 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29297654/review-of-non-invasive-vagus-nerve-stimulation-gammacore-efficacy-safety-potential-impact-on-comorbidities-and-economic-burden-for-episodic-and-chronic-cluster-headache
#9
Mkaya Mwamburi, Eric J Liebler, Andrew T Tenaglia
The FDA has cleared gammaCore (non-invasive vagus nerve stimulator [nVNS]) for the treatment of episodic cluster headache (eCH). With the exception of subcutaneous sumatriptan, all other treatments are used off label and have many limitations. The FDA approval process for devices differs from that of drugs. We performed a review of the literature to evaluate new evidence on various aspects of gammaCore treatment and impact. The ACute Treatment of Cluster Headache Studies (ACT1 and ACT2), both double-blind sham-controlled randomized trials, did not meet the primary endpoints of the trials but each demonstrated significant superiority of gammaCore among patients with eCH...
November 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29296090/clinical-and-economic-outcomes-of-a-high-touch-clinical-management-program-for-intravenous-immunoglobulin-therapy
#10
Julia Zhu, Heather S Kirkham, Gretchen Ayer, Chi-Chang Chen, Rolin L Wade, Swapna U Karkare, Chester H Robson, Jordan S Orange
Objective: To compare clinical and economic outcomes of patients who received intravenous immunoglobulin (IVIG) therapies and were managed by a clinical management program vs the outcomes of matched controls using administrative claim data. Methods: This retrospective cohort study used the PharMetrics Plus™ claim database between September 1, 2011 and June 30, 2014. Patients in the intervention group were from a "high-touch" IVIG clinical management program administered by a home infusion specialty pharmacy...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29290169/evaluating-oncology-value-based-frameworks-in-the-u-s-marketplace-and-challenges-in-real-world-application-a-multiple-myeloma-test-case
#11
Laurence M Djatche, Joseph A Goble, Grace Chun, Stefan Varga
BACKGROUND: With the continuous rise in costs for oncology drugs, the American Society of Clinical Oncology (ASCO), the Institute for Clinical and Economic Review (ICER), the Memorial Sloan Kettering Cancer Center's Drug Abacus (DrugAbacus), and the National Comprehensive Cancer Network (NCCN) have developed value-based frameworks (VBFs) to assist stakeholders in formulary and treatment decision-making processes. Since emerging VBFs have the potential to affect available treatment options for patients, it is important to understand the differences associated with these VBFs within various therapeutic areas...
January 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29285002/historical-contribution-of-pharmaceutics-to-botany-and-pharmacognosy-development
#12
REVIEW
Lejla Zunic, Armin Skrbo, Amra Dobraca
Introduction: Pharmacy and medicine belong to the oldest human activities, so the development of these sciences is closely related to the socio-economic, cultural and religious opportunities of the nations within which they have been developing. Goals: To present the historical influence of pharmacy on the development of the human being from its very beginning; To present the historical link between pharmaceutical and medical activity, as well as early development of independent pharmaceutical activity; To present the historical influence of pharmacists on the development of botany and pharmacognosy and to present the historical influence of the first written herbarium and incunabula on the development of pharmacognosy...
December 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/29284908/contribution-of-arabic-medicine-and-pharmacy-to-the-development-of-health-care-protection-in-bosnia-and-herzegovina-the-first-part
#13
REVIEW
Izet Masic, Armin Skrbo, Nabil Naser, Salih Tandir, Lejla Zunic, Senad Medjedovic, Aziz Sukalo
The time interval from the 9th to the 13th century remained known as the "Golden period of the Arab science", and a significant place among the taught sciences are occupied by Medicine and Pharmacy. In the history of medicine, Islamic medicine, also known as Arabic medicine, refers to the science of medicine developed in the Islamic Golden Age, and written in Arabic Arabs were able to use their cultural and natural resources and trade links to contribute to the strong development of pharmacy. After the collapse of the Arab rule, the Arab territorial expanses and cultural heritage were taken over by the Turks...
October 2017: Medical Archives
https://www.readbyqxmd.com/read/29284715/pharmacy-diabetes-screening-trial-protocol-for-a-pragmatic-cluster-randomised-controlled-trial-to-compare-three-screening-methods-for-undiagnosed-type-2-diabetes-in-australian-community-pharmacy
#14
Ines Krass, Rob Carter, Bernadette Mitchell, Mohammadreza Mohebbi, Sophy T F Shih, Peta Trinder, Vincent L Versace, Frances Wilson, Kevin Mc Namara
INTRODUCTION: With the rising prevalence of type 2 diabetes in Australia, screening and earlier diagnosis is needed to provide opportunities to intervene with evidence-based lifestyle and treatment options to reduce the individual, social and economic impact of the disease. The objectives of the Pharmacy Diabetes Screening Trial are to compare the clinical effectiveness and cost-effectiveness of three screening models for type 2 diabetes in a previously undiagnosed population. METHODS AND ANALYSIS: The Pharmacy Diabetes Screening Trial is a pragmatic cluster randomised controlled trial to be conducted in 363 community pharmacies across metropolitan, regional and remote areas of Australia, randomly allocated by geographical clusters to one of three groups, each with 121 pharmacies and 10 304 screening participants...
December 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/29261180/preemptive-pharmacogenetic-testing-exploring-the-knowledge-and-perspectives-of-us-payers
#15
Nicholas J Keeling, Meagen M Rosenthal, Donna West-Strum, Amit S Patel, Cyrine E Haidar, James M Hoffman
PurposePreemptive pharmacogenetic testing aims to optimize medication use by having genetic information at the point of prescribing. Payers' decisions influence implementation of this technology. We investigated US payers' knowledge, awareness, and perspectives on preemptive pharmacogenetic testing.MethodsA qualitative study was conducted using semistructured interviews. Participants were screened for eligibility through an online survey. A blended inductive and deductive approach was used to analyze the transcripts...
October 26, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29248401/health-economic-implications-of-complications-associated-with-pancreaticoduodenectomy-at-a-university-hospital-a%C3%A2-retrospective-cohort-cost-study
#16
Jason Wang, Ronald Ma, Paul Eleftheriou, Leonid Churilov, David Debono, Ray Robbins, Mehrdad Nikfarjam, Chris Christophi, Laurence Weinberg
BACKGROUND: A cost analyses of complications following pancreaticoduodenectomy (PD) was performed in a high volume hepato-biliary-pancreatic service. We hypothesised that costs are increased with both severity and number of complications; we investigated the relationship between complications and specific cost centres. METHODS: 100 patients from 2011 to 2016 were included. Data relating to their perioperative course were collected. Complications were documented by the Clavien-Dindo classification and costs were inflated and converted to 2017 USD...
December 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29243513/evaluation-of-health-care-costs-and-utilization-for-patients-with-gout-a-population-based-matched-cohort-study
#17
Yi-Yun Lee, Chao-Hsiun Tang, Jin-Hua Chen, Li-Na Kuo, Yu Ko
OBJECTIVES: To better understand the economic burden of gout patients in Taiwan, we conducted a nationwide retrospective study to compare the healthcare costs and utilization between gout and gout-free patients. METHODS: The Longitudinal Health Insurance Database (LHID) 2010 was used to identify gout cases and matched gout-free controls. Gout cases were defined as having (1) at least three instances of diagnoses of gout on medical claims or (2) one diagnosis of gout with at least one gout-related pharmacy claim in 2011...
December 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29236665/-claude-bernard%C3%A2-%C3%A2-then-and-now
#18
Peter Wise
The early life of Claude Bernard - dreamer and frustrated playwright - reveals no indication of his future scientific aptitude. Cartesian doubt, a principle that he would adhere to lifelong, clouded a failed pharmacy apprenticeship that led to medical studies in Paris - but without great success. Research was his only aim, it was made possible only by a lucrative but unsuccessful arranged marriage. His passion for work and over-riding principles of truth and proof would ultimately allow him to stand out from his peers with recognition by multiple French professional societies - and the wider scientific world...
2017: Biologie Aujourd'hui
https://www.readbyqxmd.com/read/29222044/the-effects-of-assurances-of-voluntary-compliance-on-retail-sales-to-minors-in-the-united-states-2015-2016
#19
Hongying Dai, Delwyn Catley
Multiple state attorneys generals have entered assurances of voluntary compliance (AVCs) with numerous national retail chains as an application of consumer protection laws to help prevent tobacco sales to minors. Little is known about the effectiveness of AVCs in reducing the violations of tobacco retailers for underage sales. We collected inspection data involving minors (n=53,832) on tobacco retailers in 2015 and 2016 from the Food and Drug Administration (FDA) compliance check database. Inspections on 13 national retail chains were classified into four categories: gas stations from oil companies, convenience stores, pharmacy stores, and supermarkets...
December 5, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29209527/pembrolizumab-as-second-line-therapy-in-non-small-cell-lung-cancer-in-northern-norway-budget-impact-and-expected-gain-a-model-based-analysis
#20
Jan Norum, Margareth Aarag Antonsen, Terje Tollåli, Khalid Al-Shibli, Gry Andersen, Kristin Helene Svanqvist, Nina Helbekkmo
Background: Pembrolizumab is a new drug approved in several countries for second-line therapy in non-small cell lung cancer (NSCLC) being programmed cell death ligand (PD-L1) positive. This drug has a high cost, and the cost-effectiveness ratio has been debated. Patients and methods: The budget impact to the Northern Norwegian Regional Health Authority trust of implementing pembrolizumab in second-line therapy in patients with PD-L1-positive NSCLC was calculated...
2017: ESMO Open
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