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https://www.readbyqxmd.com/read/28945049/-standardization-of-names-in-prescriptions-of-traditional-chinese-medicines
#1
Chao-Feng Li, Yu-Jun Zhang, Dong-He Fan, Meng-Jie Zhang, Xue Bai, Wen-Hua Yang, Shu-Ya Qi, Zhi-Jie Zhang, Chun-Miao Xue, Liu-Ying Mao, Jun-Ling Cao
Chinese medicine prescriptions are a type of medical documents written by doctors after they understand the patients' conditions for syndrome differentiation. Chinese medicine prescriptions are also the basis for pharmacy personnel to dispense medicines and guide patients to use drugs. It has the legal, technical and economic significances. Chinese medicine prescriptions contain such information of names, quantity and usage. Whether the names of drugs in Chinese medicine prescriptions are standardized or not is directly related to the safety and efficacy of the drugs...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28944733/performance-based-risk-sharing-arrangements-for-pharmaceutical-products-in-the-united-states-a-systematic-review
#2
Justin S Yu, Lauren Chin, Jennifer Oh, Jorge Farias
BACKGROUND: Value for money is a growing necessity in today's U.S. health care system in which drug spending is expected to increase by an average rate of 6.7% yearly through 2025. In response to uncertainty about real-world clinical and economic outcomes for many drugs, health insurers and pharmacy benefit managers (PBMs) have implemented various contracts and arrangements with drug manufacturers that can collectively be described as performance-based risk-sharing arrangements (PBRSAs)...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28926636/the-expected-and-unexpected-benefits-of-dispensing-the-exact-number-of-pills
#3
Carole Treibich, Sabine Lescher, Luis Sagaon-Teyssier, Bruno Ventelou
BACKGROUND: From November 2014 to November 2015, an experiment in French community pharmacies replaced traditional pre-packed boxes by per-unit dispensing of pills in the exact numbers prescribed, for 14 antibiotics. METHODS: A cluster randomised control trial was carried out in 100 pharmacies. 75 pharmacies counted out the medication by units (experimental group), the other 25 providing the treatment in the existing pharmaceutical company boxes (control group)...
2017: PloS One
https://www.readbyqxmd.com/read/28890020/the-national-cost-of-asthma-among-school-aged-children-in-the-united%C3%A2-states
#4
Patrick W Sullivan, Vahram Ghushchyan, Prakash Navaratnam, Howard S Friedman, Abhishek Kavati, Benjamin Ortiz, Bob Lanier
BACKGROUND: Recent research has quantified the national health care resource use (HCRU) and health care expenditure (HCE) burden associated with adult asthma; however, estimates specific to school-aged children are more than 2 decades old. OBJECTIVE: To estimate the national HCRU and HCEs attributable to asthma among school-aged children in the United States. METHODS: This was a cross-sectional retrospective analysis of school-aged children (aged 6-17 years) in the nationally representative 2007-2013 Medical Expenditure Panel Survey...
September 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28853698/prioritization-of-diseases-for-the-development-of-a-pharmaceutical-care-service-model-in-south-korea-using-the-analytic-hierarchy-process%C3%A2
#5
Kiyon Rhew, Nayoung Han, Keun-Tae Cho, Jeong-Hyun Yoon, Jung Mi Oh
OBJECTIVE: Drug therapy plays a critical role in most chronic diseases. Effectiveness of pharmaceutical care services in the improvement of clinical, social, or economic outcomes has been scientifically proven through numerous studies. In South Korea, to optimize and standardize pharmaceutical care for patients with chronic metabolic diseases, the development of a pharmaceutical care service model is needed. MATERIALS: To determine the priority of diseases in developing pharmaceutical care service models, analytic hierarchny process (AHP)analysis was used...
August 30, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28851428/social-and-economic-value-of-portuguese-community-pharmacies-in-health-care
#6
Jorge Félix, Diana Ferreira, Marta Afonso-Silva, Marta Vargas Gomes, César Ferreira, Björn Vandewalle, Sara Marques, Melina Mota, Suzete Costa, Maria Cary, Inês Teixeira, Ema Paulino, Bruno Macedo, Carlos Maurício Barbosa
BACKGROUND: Community pharmacies are major contributors to health care systems across the world. Several studies have been conducted to evaluate community pharmacies services in health care. The purpose of this study was to estimate the social and economic benefits of current and potential future community pharmacies services provided by pharmacists in health care in Portugal. METHODS: The social and economic value of community pharmacies services was estimated through a decision-model...
August 29, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28841868/a-systematic-review-of-the-effectiveness-of-policies-restricting-access-to-pregabalin
#7
Brett R Stacey, Jonathan Liss, Regina Behar, Alesia Sadosky, Bruce Parsons, Elizabeth T Masters, Patrick Hlavacek
BACKGROUND: Formularies often employ restriction policies to reduce pharmacy costs. Pregabalin, an alpha-2-delta ligand, is approved for treatment of fibromyalgia (FM); neuropathic pain (NeP) due to postherpetic neuralgia (PHN), diabetic peripheral neuropathy (pDPN), spinal cord injury; and as adjunct therapy for partial onset seizures. Pregabalin is endorsed as first-line therapy for these indications by several US and EU medical professional societies. However, restriction policies such as prior authorization (PA) and step therapy (ST) often favor less costly generic pain medications over pregabalin...
August 25, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28841003/superficial-chiral-etching-on-achiral-metal-organic-framework-for-enantioselective-sorption
#8
Xudong Hou, Tingting Xu, Yang Wang, Shengjun Liu, Jing Tong, Bo Liu
Chiral recognition and separation is of general research interests in natural product separation and the pharmacy industry. In this work, we develop a novel strategy to modify achiral porous metal-organic framework (MOF) surfaces via a superficial chiral etching process (SCEP), in which reacting a presynthesized achiral MOF with a chiral ligand produces an achiral@chiral MOF core-shell hybrid composition. SCEP creates chiral species on an achiral porous MOF surface but does not change the porosity and pore structure, enabling core-shell composition enantioselective sorption...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28835370/screening-for-atrial-fibrillation-in-canadian-pharmacies-an-economic-evaluation
#9
Jean-Eric Tarride, Lisa Dolovich, Gordon Blackhouse, Jason Robert Guertin, Natasha Burke, Veena Manja, Alex Grinvalds, Ting Lim, Jeff S Healey, Roopinder K Sandhu
BACKGROUND: Screening for undiagnosed atrial fibrillation may lead to treatment with oral anticoagulation therapy, which can decrease the risk of ischemic stroke. The objective of this study was to conduct an economic evaluation of the Program for the Identification of 'Actionable' Atrial Fibrillation in the Pharmacy Setting (PIAAF-Pharmacy), which screened 1145 participants aged 65 years or more at 30 community pharmacies in Ontario and Alberta between October 2014 and April 2015. METHODS: We used a 2-part decision model to evaluate the short- and long-term costs and quality-adjusted life-years (QALYs) of a pharmacy screening program for atrial fibrillation compared to no screening...
August 22, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28816643/pharmacometabolomics-informs-quantitative-radiomics-for-glioblastoma-diagnostic-innovation
#10
Theodora Katsila, Minos-Timotheos Matsoukas, George P Patrinos, Dimitrios Kardamakis
Applications of omics systems biology technologies have enormous promise for radiology and diagnostics in surgical fields. In this context, the emerging fields of radiomics (a systems scale approach to radiology using a host of technologies, including omics) and pharmacometabolomics (use of metabolomics for patient and disease stratification and guiding precision medicine) offer much synergy for diagnostic innovation in surgery, particularly in neurosurgery. This synthesis of omics fields and applications is timely because diagnostic accuracy in central nervous system tumors still challenges decision-making...
August 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28809128/real-world-adherence-and-economic-outcomes-associated-with-paliperidone-palmitate-versus-oral-atypical-antipsychotics-in-schizophrenia-patients-with-substance-related-disorders-using-medicaid-benefits
#11
Kruti Joshi, Marie-Hélène Lafeuille, Rhiannon Kamstra, Sean Tiggelaar, Patrick Lefebvre, Edward Kim, Yong Yue, Neeta Tandon
AIM: Compare medication utilization, costs and healthcare resource use in schizophrenia patients with substance-related disorders initiated on once-monthly paliperidone palmitate (PP1M) or an oral atypical antipsychotic (OAA). MATERIALS & METHODS: Data from six Medicaid states (07/2009-03/2015) were used to compare outcomes between PP1M and OAA patients. RESULTS: PP1M patients had higher 12-month antipsychotic adherence and persistence than OAA patients...
August 15, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28807018/the-neglected-burden-of-snakebites-in-cameroon-a-review-of-the-epidemiology-management-and-public-health-challenges
#12
Joel Noutakdie Tochie, Mazou N Temgoua, Tsi Njim, Danwang Celestin, Ronni Tankeu, Njinkeng J Nkemngu
OBJECTIVES: Snakebite is an underestimated medical and surgical emergency in developing countries responsible for a high disease burden. Optimal management of snake envenomation in these resource-limited settings is precluded by several public health challenges. In this review, we discuss the disease burden of snakebites in Cameroon and the public health challenges of its management in view of making recommendations essential for policy-making. MEDLINE, African Journals Online and Google Scholar were searched from January 1990 to February 2017 for studies addressing snakebite in Cameroon...
August 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28805473/the-impact-of-persistence-with-mirabegron-usage-vs-switching-to-onabotulinumtoxina-on-healthcare-costs-and-resource-utilization-in-patients-with-overactive-bladder-in-the-united-states
#13
Daniel Bin Ng, Robert Espinosa, Scott J Johnson, David Walker, Katherine Gooch
AIMS: To compare healthcare costs and resource utilization in patients with overactive bladder (OAB) in the US who switch from mirabegron to onabotulinumtoxinA (onabotA) with those who persist on mirabegron. MATERIALS AND METHODS: A retrospective observational claims analysis of the OptumHealth Administrative Claims database conducted between April 1, 2012 and September 30, 2015 used medical and pharmacy claims to identify patients with at least one OAB diagnosis who switched from mirabegron to onabotA (onabotA group) or persisted on mirabegron for at least 180 days (mirabegron persisters)...
September 4, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28805105/economic-burden-of-multiple-myeloma-among-patients-in-successive-lines-of-therapy-in-the-united-states
#14
Joanna P MacEwan, Katharine Batt, Wes Yin, Desi Peneva, Steve Sison, Seanna Vine, Clara Chen
This study characterized the costs of multiple myeloma (MM) during first-line (1L), second-line (2L) and third-line (3L) treatment from the US payer perspective. Patients with ≥2 outpatient or ≥1 inpatient claims with a primary MM diagnosis and 12 months continuous enrollment post index were identified in a retrospective claims database between 1 July 2006 and 30 June 2013. A cost per-patient per-month (PPPM) metric was used to calculate total all-cause and anti-MM pharmacy costs in 1L, 2L, and 3L treatment...
August 13, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28793065/infrastructure-evaluation-of-pharmaceutical-services-in-the-national-health-system-of-minas-gerais
#15
Mariana Michel Barbosa, Marina Morgado Garcia, Renata Cristina Rezende Macedo do Nascimento, Edna Afonso Reis, Augusto Afonso Guerra, Francisco De Assis Acurcio, Juliana Álvares
Objectives: To characterize the infrastructure of public pharmacies in Minas Gerais, comparing municipalities that have received the RFM program to the ones that haven't, in order to verify if the State's Economic Incentives implied in improvement of local Pharmaceutical Services (PS). Methods: A cross-sectional, exploratory, evaluative study in a representative sample of the municipalities of Minas Gerais. Face-to-face interviews were conducted with users, physicians, and drug dispensers, as well as observation of pharmacy facilities and telephone interviews with municipal officials from the PS...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28791891/the-economic-burden-of-urinary-tract-infection-and-pressure-ulceration-in-acute-traumatic-spinal-cord-injury-admissions-evidence-for-comparative-economics-and-decision-analytics-from-a-matched-case-control-study
#16
Barry A B White, Nicolas Dea, John T Street, Christiana L Cheng, Carly S Rivers, Najmedden Attabib, Brian K Kwon, Charles G Fisher, Marcel F Dvorak
Secondary complications of spinal cord injury (SCI) are a burden to affected individuals and the rest of society. There is limited evidence of the economic burden or cost of complications in SCI populations in Canada, however, which is necessary for comparative economic analyses and decision analytic modeling of possible solutions to these common health problems. Comparative economic analyses can inform resource allocation decisions, but the outputs are only as good as the inputs. In this article, new evidence of the excess or incremental costs of urinary tract infection (UTI) and pressure ulceration (PU) in acute traumatic SCI from an exploratory case series analysis of admissions to a Level I specialized Canadian spine facility (2008-2013) is presented...
September 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28782449/real-world-economic-burden-of-hematopoietic-cell-transplantation-among-a-large-us-commercially-insured-population-with-hematologic-malignancies
#17
Machaon Bonafede, Akshara Richhariya, Qian Cai, Neil C Josephson, Donna McMorrow, Phillip M Garfin, Miguel-Angel Perales
AIMS: Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are performed in the US annually. This study aims to study the healthcare resource utilization and costs among commercially-insured patients with hematologic malignancies who received autologous HCT (auto-HCT) and allogeneic HCT (allo-HCT) in the US. MATERIALS AND METHODS: Adult patients with hematologic malignancies undergoing auto- or allo-HCT between January 1, 2011 and June 30, 2014 were identified in the Truven Health MarketScan Research Databases...
August 7, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28776320/cost-effectiveness-of-support-for-people-starting-a-new-medication-for-a-long-term-condition-through-community-pharmacies-an-economic-evaluation-of-the-new-medicine-service-nms-compared-with-normal-practice
#18
Rachel A Elliott, Lukasz Tanajewski, Georgios Gkountouras, Anthony J Avery, Nick Barber, Rajnikant Mehta, Matthew J Boyd, Asam Latif, Antony Chuter, Justin Waring
BACKGROUND: The English community pharmacy New Medicine Service (NMS) significantly increases patient adherence to medicines, compared with normal practice. We examined the cost effectiveness of NMS compared with normal practice by combining adherence improvement and intervention costs with the effect of increased adherence on patient outcomes and healthcare costs. METHODS: We developed Markov models for diseases targeted by the NMS (hypertension, type 2 diabetes mellitus, chronic obstructive pulmonary disease, asthma and antiplatelet regimens) to assess the impact of patients' non-adherence...
August 3, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28769577/social-and-economic-burden-of-patients-with-influenza-like-illness-and-clinically-diagnosed-flu-treated-at-various-health-facilities-in-vietnam
#19
Trung Quang Vo, Usa Chaikledkaew, Minh Van Hoang, Arthorn Riewpaiboon
Influenza is a malady related to the human respiratory system, and its influenza-like illness (ILI) can cause an economic and social burden, especially among children and the elderly. This study was conducted to estimate the cost of illness based on a social perspective of ILI cases. A prospective study was conducted between February and March of 2016 in pharmacies, private clinics at Khanh Hoa, Lam Dong, Tay Ninh, Dong Nai Province, and Ho Chi Minh City, and Hospital of Tropical Diseases. Demographic and clinical information were collected by face-to-face interview...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28760001/association-of-obesity-with-healthcare-utilization-and-costs-in-a-medicare-population
#20
Brandon T Suehs, Pravin Kamble, Joanna Huang, Mette Hammer, Jonathan Bouchard, Mary E Costantino, Andrew Renda
OBJECTIVES: To examine the association of obesity on healthcare resource utilization and costs in a Medicare population. METHODS: This study was a retrospective cohort study using Humana Medicare Advantage (MA) claims data. Body mass index (BMI) was assessed using ICD-9-CM status codes (V85 hierarchy) that have been validated in the data source to classify patients into BMI categories: Normal (N), Overweight (Ow), Obese class I (ObI), Obese class II (ObII), and Obese class III (ObIII)...
August 1, 2017: Current Medical Research and Opinion
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