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Disseminated histoplasmosis

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https://www.readbyqxmd.com/read/28647712/disseminated-histoplasmosis-in-a-patient-with-hiv-diagnosed-by-simple-bedside-investigations
#1
Pongsakorn Buraphat, Wannarat Pongpirul, Patama Suttha
No abstract text is available yet for this article.
June 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28626627/tonsillar-ulceration-as-manifestation-of-disseminated-african-histoplasmosis-in-an-immunocompetent-portuguese-host
#2
L Cardoso, C Silva, N Marques, C Veríssimo
Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia. Most of the cases are asymptomatic. Disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. We report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent Portuguese host, as manifestation of disseminated African histoplasmosis 45 years later after living 3 years in Africa...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28617878/granulomatous-hepatitis-a-rare-primary-manifestation-of-disseminated-histoplasmosis-in-a-renal-transplant-recipient
#3
Jiten P Kothadia, Vyshnavi Kone, Shah Giashuddin
No abstract text is available yet for this article.
June 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28554708/protothecosis-in-a-patient-with-t-cell-lymphocytic-leukemia
#4
Mariana S Fernández, Florencia D Rojas, María E Cattana, Javier E Mussin, María de Los Ángeles Sosa, Carlos D Benzoni, Gustavo E Giusiano
Human protothecosis is a rare infection caused by algae of the genus Prototheca. Prototheca wickerhamii has been recognized as the main species that causes infection in immunocompromised hosts with deficits in innate or cellular immunity. We report a case of persisting subcutaneous protothecosis in a patient with T-cell large granular lymphocyte leukemia, who also presented a history of disseminated histoplasmosis.
May 27, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28548709/-polka-dot-macrophages-on-cytology-of-bilateral-adrenal-masses-nailing-disseminated-histoplasmosis
#5
Sumit Grover, Pavneet Kaur Selhi, Neena Sood, Ridhi Sood, Harpreet Kaur
Histoplasma capsulatum is a saprophytic fungus that in immunocompetent individuals causes self-limited pulmonary infection; however, in immunosuppressed patients involvement of the reticuloendothelial system, alimentary tract, urinary tract, and central nervous system is fairly common. Rarely patients present with bilateral adrenal masses which mimic tuberculosis and metastasis on radiology because of associated central necrosis. Ultrasound guided FNAC aided by special stains like Periodic Acid Schiff (PAS) and Gomori Methenamine Silver (GMS) may help in early diagnosis in such dubious cases...
May 26, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28530163/gastrointestinal-histoplasmosis-a-case-series
#6
Rashi Sharma, Lipika Lipi, Smeeta Gajendra, Ishani Mohapatra, Ruchika K Goel, Rajan Duggal, Smruti Ranjan Mishra, Dheeraj Gautam
Histoplasmosis is an invasive mycosis caused by inhalation of the spores of dimorphic fungi Histoplasma capsulatum. The disease manifests in the lung as acute or chronic pulmonary histoplasmosis and in severe cases gets disseminated in multiple organs like skin, adrenal gland, central nervous system, lymph node, liver, spleen, bone marrow, and gastrointestinal tract. It occurs most commonly in immunodeficient patients like HIV-positive patients and transplant recipients, while immunocompetent hosts are affected rarely...
May 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28528522/reconstitution-inflammatory-syndrome-like-reactive-hemophagocytic-syndrome-associated-with-disseminated-histoplasmosis-in-a-hiv-patient
#7
REVIEW
Sandra M Gómez-Espejo, Julián Olalla-Sierra, Pilar Marí-Jiménez, Teresa Pereda-Salguero, Javier Pérez-Stachowski, Javier de-la-Torre-Lima, Alfonso Del-Arco-Jiménez, José L Prada-Pardal
We describe an unusual clinical association of disseminated histoplasmosis with reactive hemophagocytic syndrome. We report the case of a new HIV-positive patient with reconstitution inflammatory syndrome like reactive hemophagocytic syndrome associated with disseminated histoplasmosis. We describe the clinical case, the procedures performed, the treatment provided and the patient's evolution. A figure of liver biopsy Grocott's silver methenamine stain that shows lots of uniform ovoid yeasts in portal spaces' macrophages that supports the diagnosis of disseminated histoplasmosis in our case...
May 20, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28476105/case-of-disseminated-histoplasmosis-in-a-hiv-infected-patient-revealed-by-nasal-involvement-with-maxillary-osteolysis
#8
A C Lehur, M Zielinski, J Pluvy, V Grégoire, S Diamantis, A Bleibtreu, C Rioux, A Picard, D Vallois
BACKGROUND: Disseminated Histoplasmosis (DH) is a rare manifestation of Acquired Immune Deficiency Syndrome (AIDS) in European countries. Naso-maxillar osteolysis due to Histoplasma capsulatum var. capsulatum (Hcc) is unusual in endemic countries and has never been reported in European countries. Differential diagnoses such as malignant tumors, cocaine use, granulomatosis, vasculitis and infections are more frequently observed and could delay and/or bias the final diagnosis. CASE PRESENTATION: We report the case of an immunocompromised patient infected by Human Immunodeficiency Virus (HIV) with naso-maxillar histoplasmosis in a non-endemic country...
May 5, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28474430/unusual-presentation-of-disseminated-histoplasmosis-in-an-immunocompetent-patient
#9
Manju Kumari, Madhumitha Udayakumar, Manju Kaushal, Garima Baweja Madaan
Disseminated histoplasmosis (DH) is a systemic granulomatous disease caused by the fungus Histoplasma capsulatum. This disease occurs mainly in immunocompromised individuals with CD 4 counts less than 200 cell/µL and is rarely noted in immunocompetent person. In India, this disease has been reported from several parts of the country of which most cases are from eastern India which is considered to be endemic for this disease. Inhalation of the spores can lead to a self-limiting flulike illness in immunocompetent hosts...
May 4, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28470019/pulmonary-histoplasma-infection-after-allogeneic-hematopoietic-stem-cell-transplantation-case-report-and-review-of-the-literature
#10
Mukil Natarajan, Matthew J Swierzbinski, Sandra Maxwell, Adrian M Zelazny, Gary A Fahle, Martha Quezado, John Barrett, Minoo Battiwalla, Michail S Lionakis
Histoplasmosis causes a wide spectrum of clinical illness, including disseminated infection in the immunocompromised. We report a case of pulmonary histoplasmosis in an allogeneic stem cell transplant recipient and review the literature on this topic. Histoplasmosis in this patient population is uncommon, but it is associated with poor outcome.
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28462780/-african-histoplamosis-a-report-of-three-pediatric-cases
#11
REVIEW
J R Mabiala Babela, C Mboutol Mandavo, R Nika Evrard, B Ossibi Ibara, L Lamah, L C Ollandzobo Ikobo, A Mouko, J F Peko
Histoplasmosis duboisii (Histoplasma capsulatum var duboisii) is uncommon disease especially in children. It is observed in Africa where the incidence is unknown. The authors report a series of three pediatric cases. The report concerned 2 girls and one boy who were 3, 9 and 4 year-old, respectively. Symptoms evolved for more than two months in each case. At admission, we found fever and poor general condition. Observed lesions were lymphnodes localisation disseminated (cases 1 and 2), subcutaneous (cold abscess) and cutaneous simulating molluscum contagiosum (case 2), osteoarticular (cases 2 and 3), abdominal including peritoneal and hepatosplenic (case 1)...
April 24, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28457513/fatal-disseminated-histoplasmosis-presenting-as-fuo-in-an-immunocompetent-italian-host
#12
Alessandro Bonsignore, Giulio Fraternali Orcioni, Rosario Barranco, Francesco De Stefano, Jean Louis Ravetti, Francesco Ventura
Histoplasmosis is a relatively rare infectious disease endemic to certain geographic areas such as East Africa, eastern and central United States, western Mexico, Central and South America. Disseminated histoplasmosis has been reported mainly in immunocompromised hosts and in AIDS patients. In this paper we report on a fatal case of undiagnosed disseminated histoplasmosis presenting as fever of unknown origin (FUO) in a 43-year-old Italian woman who, although splenectomized 5years earlier due to a motor vehicle accident, was otherwise immunocompetent...
March 2017: Legal Medicine
https://www.readbyqxmd.com/read/28431110/african-histoplasmosis-new-clinical-and-microbiological-insights
#13
C Valero, S Gago, M C Monteiro, A Alastruey-Izquierdo, M J Buitrago
African histoplasmosis is defined as the fungal infection caused by Histoplasma capsulatum var. duboisii (Hcd). Studies focused on distinguishing Hcd and H. capsulatum var. capsulatum (Hcc), which coexist in Africa, are scarce or outdated, and African strains are continuously underrepresented. In this work, 13 cases of African patients with histoplasmosis diagnosed in the Spanish Mycology Reference Laboratory have been reviewed showing that 77% had disseminated disease and AIDS as underlying disease although Hcd infection has been classically considered a rare presentation in AIDS patients...
April 20, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28380270/oral-ulcers-associated-with-bone-destruction-as-the-primary-manifestation-of-histoplasmosis-in-an-immunocompetent-patient
#14
LETTER
J A Figueira, D Camilo Júnior, É R Biasoli, G I Miyahara, D G Bernabé
No abstract text is available yet for this article.
April 5, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28379418/histoplasmosis-in-pleural-effusion-in-a-23-year-old-man-with-mixed-phenotype-acute-leukemia
#15
Sudha Sharma, Priya Singh, Kamal Kant Sahu, Arvind Rajwanshi, Pankaj Malhotra, Shano Naseem
Histoplasmosis has been observed in patients with immunosuppression in the form of isolated pulmonary involvement and disseminated disease. However, very few cases of this type that involved pleural effusion have been reported, and none have been reported in a case individual with mixed-phenotype acute leukemia (MPAL). Herein, we report a case involving a 23 year old Punjabi man having fever and breathlessness in the postinduction therapy period for mixed-phenotype acute leukemia (MPAL) with diagnosis of histoplasmosis based on the results of pleural fluid cytologic testing...
April 1, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28349614/progressive-histoplasmosis-with-hemophagocytic-lymphohistiocytosis-and-epithelioid-cell-granulomatosis-a-case-report-and-review-of-the-literature
#16
Arik Bernard Schulze, Britta Heptner, Torsten Kessler, Birgit Baumgarten, Viorelia Stoica, Michael Mohr, Rainer Wiewrodt, Viktoria Susanne Warneke, Wolfgang Hartmann, Jörg Wüllenweber, Christoph Schülke, Michael Schäfers, Dunja Wilmes, Karsten Becker, Lars Henning Schmidt, Andreas H Groll, Wolfgang E Berdel
Histoplasmosis in central Europe is a rare fungal disease with diverse clinical presentations. Apart from acute pulmonary histoplasmosis and involvement of the central nervous system, the most serious clinical presentation is progressive disseminated histoplasmosis which is generally associated with severe immunodeficiency and, in particular, advanced human immunodeficiency virus infection. Here, we report on an immunocompetent female residing in a non-endemic area, presenting with progressive disseminated histoplasmosis after a remote travel history to Thailand and Costa Rica...
March 27, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28348765/progressive-disseminated-histoplasmosis-mimicking-a-flare-of-systemic-lupus-erythematosus-a-european-case-report
#17
M L M van Doorn-Schepens, E J Peters, R M van Vugt, J I van der Spoel, K van Dijk
INTRODUCTION: Diagnosing progressive disseminated histoplasmosis (PDH) in patients with systemic lupus erythematosus (SLE) is diagnostically challenging. Since PDH is lethal when untreated, awareness of this infection in patients with SLE is of utmost importance. To the best of our knowledge, this is the first description of a case of PDH in a patient with SLE in Europe. CASE PRESENTATION: A 56-year-old woman of Surinamese descent with a history of SLE, presented with fever and polyarthritis...
August 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28327821/disseminated-histoplasmosis-diagnosed-in-a-peripheral-blood-smear
#18
André Luiz Maltos, Evaldo Maia, Cristina da Cunha Hueb Barata de Oliveira
No abstract text is available yet for this article.
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28317569/oral-fungal-infections-diagnosis-and-management
#19
REVIEW
David R Telles, Niraj Karki, Michael W Marshall
Oral and maxillofacial fungal infections can appear in high-risk patients, including those immunocompromised. This article explores common oral manifestations of fungal infections in the oral cavity as primary lesions or as a result of disseminated disease. By far the most common oral fungal infection experienced in dentistry is oral candidiasis, which is reviewed in depth from simple oral infections to invasive candidiasis. The review aids the dental practitioner in understanding the full scope of Candida infections and other fungal infections...
April 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28273974/primary-cutaneous-histoplasmosis-masquerading-as-lepromatous-leprosy
#20
Jenna Blah Bhattacharya, Poonam Rani, Radhika Aggarwal, Seema Kaushal
Histoplasmosis is a genus of dimorphic fungi having various varieties of which the commonest one causing infection is Histoplasma capsulatum known to cause histoplasmosis. It has a varied disease spectrum ranging from an acute infection to chronic disease especially in lungs, disseminated disease and cutaneous disorder. Histoplasma capsulatum usually causes subclinical infection and serious infections only manifest in immunocompromised patients. Frank cases of infection are seen in pulmonary histoplasmosis...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
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