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https://www.readbyqxmd.com/read/29321361/a-novel-contiguous-deletion-involving-ndp-maob-and-efhc2-gene-in-a-patient-with-familial-norrie-disease-bilateral-blindness-and-leucocoria-without-other-deficits
#1
Bei Jia, Liping Huang, Yaoyu Chen, Siping Liu, Cuihua Chen, Ke Xiong, Lanlin Song, Yulai Zhou, Xinping Yang, Mei Zhong
Contiguous microdeletions of the Norrie disease pseudoglioma (NDP) region on chromosome Xp11.3 have been widely confirmed as contributing to the typical clinical features of Norrie disease (ND). However, the precise relation between genotype and phenotype could vary. The contiguous deletion of NDP and its neighbouring genes, MAOA/B and EFHC2, reportedly leads to syndromic clinical features such as microcephaly, intellectual disability, and epilepsy. Herewe report a novel contiguous microdeletion of the NDP region containing the MAOB and EFHC2 genes,which causes eye defects but no cognitive disability...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29219540/noncollinear-magnetic-structure-and-multipolar-order-in-eu_-2-ir_-2-o_-7
#2
Yilin Wang, Hongming Weng, Liang Fu, Xi Dai
The magnetic properties of the pyrochlore iridate material Eu_{2}Ir_{2}O_{7} (5d^{5}) have been studied based on first principles calculations, where the crystal field splitting Δ, spin-orbit coupling (SOC) λ, and Coulomb interaction U within Ir 5d orbitals all play significant roles. The ground state phase diagram has been obtained with respect to the strength of SOC and Coulomb interaction U, where a stable antiferromagnetic ground state with all-in-all-out (AIAO) spin structure has been found. In addition, another antiferromagnetic state with energy close to AIAO has also been found to be stable...
November 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29218423/early-intraocular-pressure-change-after-peripheral-iridotomy-with-ultralow-fluence-pattern-scanning-laser-and-nd-yag-laser-in-primary-angle-closure-suspect-kowloon-east%C3%A2-pattern-scanning-laser-study-report-no-3
#3
Jeffrey Chi Wang Chan, Bonnie Nga Kwan Choy, Orlando Chia Chieh Chan, Kenneth Kai Wang Li
PURPOSE: Our purpose was to assess the early intraocular pressure (IOP) changes of ultralow fluence laser iridotomy using pattern scanning laser followed by neodymium:yttrium-aluminum-gamet (Nd:YAG) laser. METHODS: This is a prospective interventional study. Thirty-three eyes of 33 adult Chinese primary angle-closure suspect subjects were recruited for prophylactic laser peripheral iridotomy. Sequential laser peripheral iridotomy was performed using pattern scanning laser followed by Nd:YAG laser...
December 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29165421/-outcomes-of-intraocular-lens-implantation-in-the-absence-of-capsular-support-a-review-of-current-literature
#4
A V Gushchin, N V Kadatskaya
Тhe prevalence of complications associated with the deficiency or absence of capsular support in cataract patients is 5-15%. Moreover, approximately 20% of patients have an inconspicuous zonular weakness, which is often left undetected preoperatively. AIM: to classify and comparatively analyze the latest published data on the outcomes of various kinds of complicated cataract surgery. MATERIAL AND METHODS: Analysis of available literature on the subject of research published in 2003-2016...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29157308/characterization-of-the-upper-and-lower-respiratory-tract-microbiota-in-piedmontese-calves
#5
Isabella Nicola, Francesco Cerutti, Elena Grego, Iride Bertone, Paola Gianella, Antonio D'Angelo, Simone Peletto, Claudio Bellino
BACKGROUND: The microbiota of the bovine upper respiratory tract has been recently characterized, but no data for the lower respiratory tract are available. A major health problem in bovine medicine is infectious bronchopneumonia, the most common respiratory syndrome affecting cattle. With this study, we used 16S rRNA gene sequencing to characterize and compare the microbial community composition of the upper and lower respiratory tracts in calves. RESULTS: The microbiota of the upper (nasal swab [NS]) and the lower (trans-tracheal aspiration [TTA]) respiratory tracts of 19 post-weaned Piedmontese calves with (8/19) and without (11/19) clinical signs of respiratory disease, coming from six different farms, was characterized by 16S rRNA gene metabarcoding...
November 21, 2017: Microbiome
https://www.readbyqxmd.com/read/29082081/human-iris-three-dimensional-imaging-at-micron-resolution-by-a-micro-plenoptic-camera
#6
Hao Chen, Maria A Woodward, David T Burke, V Swetha E Jeganathan, Hakan Demirci, Volker Sick
A micro-plenoptic system was designed to capture the three-dimensional (3D) topography of the anterior iris surface by simple single-shot imaging. Within a depth-of-field of 2.4 mm, depth resolution of 10 µm can be achieved with accuracy (systematic errors) and precision (random errors) below 20%. We demonstrated the application of our micro-plenoptic imaging system on two healthy irides, an iris with naevi, and an iris with melanoma. The ridges and folds, with height differences of 10~80 µm, on the healthy irides can be effectively captured...
October 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/29055045/diagnostic-relevance-of-ige-sensitization-profiles-to-eight-recombinant-phleum-pratense-molecules
#7
Francesca Cipriani, Carla Mastrorilli, Salvatore Tripodi, Giampaolo Ricci, Serena Perna, Valentina Panetta, Riccardo Asero, Arianna Dondi, Annamaria Bianchi, Nunzia Maiello, Michele Miraglia Del Giudice, Tullio Frediani, Francesco Macrì, Sandra Lucarelli, Iride Dello Iacono, Maria Francesca Patria, Elena Varin, Diego Peroni, Loredana Chini, Viviana Moschese, Roberto Bernardini, Giuseppe Pingitore, Umberto Pelosi, Mariangela Tosca, Francesco Paravati, Ifigenia Sfika, Andrea Di Rienzo Businco, Calotta Povesi Dascola, Pasquale Comberiati, Simone Frediani, Caterina Lambiase, Maria Carmen Verga, Diego Faggian, Mario Plebani, Mauro Calvani, Carlo Caffarelli, Paolo Maria Matricardi
BACKGROUND: Grass pollen-related seasonal allergic rhinoconjunctivitis (SARg) is clinically heterogeneous in severity, comorbidities and response to treatment. The component-resolved diagnostics disclosed also a high heterogeneity at molecular level. Our study aimed at analyzing the characteristics of the IgE sensitization to Phleum pratense molecules and investigating the diagnostic relevance of such molecules in childhood. METHODS: We examined 1120 children (age 4-18y) with SARg...
October 20, 2017: Allergy
https://www.readbyqxmd.com/read/29047513/bow-shaped-caustics-from-conical-prisms-a-13th-century-account-of-rainbow-formation-from-robert-grosseteste-s-de-iride
#8
Joshua S Harvey, Hannah E Smithson, Clive R Siviour, Giles E M Gasper, Sigbjørn O Sønnesyn, Brian K Tanner, Tom C B McLeish
The rainbow has been the subject of discussion across a variety of historical periods and cultures, and numerous optical explanations have been suggested. Here, we further explore the scientific treatise De iride [On the Rainbow] written by Robert Grosseteste in the 13th century. Attempting to account for the shape of the rainbow, Grosseteste bases his explanation on the optical properties of transparent cones, which he claims can give rise to arc-shaped projections through refraction. By stating that atmospheric phenomena are reducible to the geometric optics of a conical prism, the De iride lays out a coherent and testable hypothesis...
July 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29038538/correlated-states-in-%C3%AE-li2iro3-driven-by-applied-magnetic-fields
#9
Alejandro Ruiz, Alex Frano, Nicholas P Breznay, Itamar Kimchi, Toni Helm, Iain Oswald, Julia Y Chan, R J Birgeneau, Zahirul Islam, James G Analytis
Magnetic honeycomb iridates are thought to show strongly spin-anisotropic exchange interactions which, when highly frustrated, lead to an exotic state of matter known as the Kitaev quantum spin liquid. However, in all known examples these materials magnetically order at finite temperatures, the scale of which may imply weak frustration. Here we show that the application of a relatively small magnetic field drives the three-dimensional magnet β-Li2IrO3 from its incommensurate ground state into a quantum correlated paramagnet...
October 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28981260/cu2iro3-a-new-magnetically-frustrated-honeycomb-iridate
#10
Mykola Abramchuk, Cigdem Ozsoy-Keskinbora, Jason W Krizan, Kenneth R Metz, David C Bell, Fazel Tafti
We present the first copper iridium binary metal oxide with the chemical formula Cu2IrO3. The material is synthesized from the parent compound Na2IrO3 by a topotactic reaction where sodium is exchanged with copper under mild conditions. Cu2IrO3 has the same monoclinic space group (C2/c) as Na2IrO3 with a layered honeycomb structure. The parent compound Na2IrO3 is proposed to be relevant to the Kitaev spin liquid on the basis of having Ir(4+) with an effective spin of 1/2 on a honeycomb lattice. Remarkably, whereas Na2IrO3 shows a long-range magnetic order at 15 K and fails to become a true spin liquid, Cu2IrO3 remains disordered until 2...
October 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28959822/solution-of-the-heavily-stacking-faulted-crystal-structure-of-the-honeycomb-iridate-h3liir2o6
#11
Sebastian Bette, Tomohiro Takayama, Kentaro Kitagawa, Riku Takano, Hidenori Takagi, Robert E Dinnebier
A powder sample of pure H3LiIr2O6 was synthesized from α-Li2IrO3 powder by a soft chemical replacement of Li(+) with H(+). The crystal structure of H3LiIr2O6 consists of sheets of edge sharing LiO6- and IrO6-octahedra forming a honeycomb network with layers stacked in a monoclinic distorted HCrO2 type pattern. Heavy stacking faulting of the sheets is indicated by anisotropic peak broadening in the X-ray powder diffraction (XRPD) pattern. The ideal, faultless crystal structure was obtained by a Rietveld refinement of the laboratory XRPD pattern while using the LiIr2O6(3-)-layers of α-Li2IrO3 as a starting model...
November 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28951959/-iridal-color-changing-in-ocular-masquerade-syndrome
#12
S Waibel, K Pillunat, L Pillunat
No abstract text is available yet for this article.
September 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28949730/designing-kitaev-spin-liquids-in-metal-organic-frameworks
#13
Masahiko G Yamada, Hiroyuki Fujita, Masaki Oshikawa
Kitaev's honeycomb lattice spin model is a remarkable exactly solvable model, which has a particular type of spin liquid (Kitaev spin liquid) as the ground state. Although its possible realization in iridates and α-RuCl_{3} has been vigorously discussed recently, these materials have substantial non-Kitaev direct exchange interactions and do not have a spin liquid ground state. We propose metal-organic frameworks (MOFs) with Ru^{3+} (or Os^{3+}), forming the honeycomb lattice as promising candidates for a more ideal realization of Kitaev-type spin models, where the direct exchange interaction is strongly suppressed...
August 4, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28947738/correlation-induced-electron-hole-asymmetry-in-quasi-two-dimensional-iridates
#14
Ekaterina M Pärschke, Krzysztof Wohlfeld, Kateryna Foyevtsova, Jeroen van den Brink
The resemblance of crystallographic and magnetic structures of the quasi-two-dimensional iridates Ba2IrO4 and Sr2IrO4 to La2CuO4 points at an analogy to cuprate high-Tc superconductors, even if spin-orbit coupling is very strong in iridates. Here we examine this analogy for the motion of a charge (hole or electron) added to the antiferromagnetic ground state. We show that correlation effects render the hole and electron case in iridates very different. An added electron forms a spin polaron, similar to the cuprates, but the situation of a removed electron is far more complex...
September 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28807716/iritectol-g-a-novel-iridal-type-triterpenoid-from-iris-tectorum-displays-anti-epileptic-activity-in-vitro-through-inhibition-of-sodium-channels
#15
Chunlei Zhang, Juan Chen, Fang Zhao, Ruoyun Chen, Dequan Yu, Zhengyu Cao
Iritectol G, a novel iridal-type triterpenoid containing an uncommon tetrahydrofuran moiety, was isolated from the rhizomes of Iris tectorum. The structure was elucidated by comprehensive spectroscopic analysis. Iritectol G inhibited spontaneous and 4-aminopyridine-evoked calcium oscillations in primary cultured neocortical neurons with IC50 values of 8.2μM and 12.5μM, respectively. Further electrophysiological study demonstrated that iritectol G preferred to interact with inactivated state of voltage-gated sodium channel with an IC50 value of 7...
October 2017: Fitoterapia
https://www.readbyqxmd.com/read/28798487/epitaxial-thin-films-of-pyrochlore-iridate-bi2-xir2-yo7-%C3%AE-structure-defects-and-transport-properties
#16
W C Yang, Y T Xie, W K Zhu, K Park, A P Chen, Y Losovyj, Z Li, H M Liu, M Starr, J A Acosta, C G Tao, N Li, Q X Jia, J J Heremans, S X Zhang
While pyrochlore iridate thin films are theoretically predicted to possess a variety of emergent topological properties, experimental verification of these predictions can be obstructed by the challenge in thin film growth. Here we report on the pulsed laser deposition and characterization of thin films of a representative pyrochlore compound Bi2Ir2O7. The films were epitaxially grown on yttria-stabilized zirconia substrates and have lattice constants that are a few percent larger than that of the bulk single crystals...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28765523/robust-spin-correlations-at-high-magnetic-fields-in-the-harmonic-honeycomb-iridates
#17
K A Modic, B J Ramshaw, J B Betts, Nicholas P Breznay, James G Analytis, Ross D McDonald, Arkady Shekhter
The complex antiferromagnetic orders observed in the honeycomb iridates are a double-edged sword in the search for a quantum spin-liquid: both attesting that the magnetic interactions provide many of the necessary ingredients, while simultaneously impeding access. Focus has naturally been drawn to the unusual magnetic orders that hint at the underlying spin correlations. However, the study of any particular broken symmetry state generally provides little clue about the possibility of other nearby ground states...
August 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28753323/two-dimensional-j_-eff-1-2-antiferromagnetic-insulator-unraveled-from-interlayer-exchange-coupling-in-artificial-perovskite-iridate-superlattices
#18
Lin Hao, D Meyers, Clayton Frederick, Gilberto Fabbris, Junyi Yang, Nathan Traynor, Lukas Horak, Dominik Kriegner, Yongseong Choi, Jong-Woo Kim, Daniel Haskel, Phil J Ryan, M P M Dean, Jian Liu
We report an experimental investigation of the two-dimensional J_{eff}=1/2 antiferromagnetic Mott insulator by varying the interlayer exchange coupling in [(SrIrO_{3})_{1}, (SrTiO_{3})_{m}] (m=1, 2 and 3) superlattices. Although all samples exhibited an insulating ground state with long-range magnetic order, temperature-dependent resistivity measurements showed a stronger insulating behavior in the m=2 and m=3 samples than the m=1 sample which displayed a clear kink at the magnetic transition. This difference indicates that the blocking effect of the excessive SrTiO_{3} layer enhances the effective electron-electron correlation and strengthens the Mott phase...
July 14, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28695843/magnetic-impurity-doping-induced-spin-glass-state-and-short-range-zigzag-order-in-the-honeycomb-iridate-na2iro3
#19
W P Cai, Z R Yan, R M Liu, M H Qin, M Zeng, X B Lu, X S Gao, J-M Liu
Based on the modified Heisenberg-Kitaev model, the effects of magnetic substitution on the magnetic properties of the honeycomb-lattice iridate [Formula: see text] [Formula: see text] are studied using Monte Carlo simulations. It is observed that the long-range zigzag state of the original system is rather fragile and can be replaced by a spin-glass state even for small substitution, well consistent with the experimental observation in Ru-substituted samples (Mehlawat et al 2015 Phys. Rev. B 92 134412). Both the disordered Heisenberg and Kitaev interactions caused by the magnetic ion-doping are suggested to be responsible for the magnetic phase transitions in the system...
October 11, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28693457/calculation-of-iris-claw-iol-power-for-correction-of-late-in-the-bag-iol-complex-dislocation
#20
REVIEW
Valentín Huerva, Francisco J Ascaso, Isabel Caral, Andrzej Grzybowski
BACKGROUND: To assess the constants and formula for aphakia correction with iris-claw IOLs to achieve the best refractive status in cases of late in-the-bag IOL complex dislocation. METHODS: A literature search was performed. The following data were obtained: Iris-claw IOL model, Iridal or retroiridal enclavation, A-constant, ultrasound or optical biometry, formula employed and refractive outcomes. Acceptable emmetropia was considered if the resulting spherical equivalent (SE) was within ±1...
July 11, 2017: BMC Ophthalmology
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