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https://www.readbyqxmd.com/read/29780932/case-series-pyramidal-cataracts-intact-irides-and-nystagmus-from-three-novel-pax6-mutations
#1
Bharesh K Chauhan, Anagha Medsinge, Matthew P Baumgartner, Hannah L Scanga, Smaragda Kamakari, Eva Gajdosova, Carlos J Camacho, Ken K Nischal
Purpose: To investigate the association between novel PAX6 mutations to bilateral anterior pyramidal congenital cataracts (APyC), complete and intact irides, and nystagmus. Observations: This is a retrospective observational case series in a multi-center setting with genetic testing. Three female patients were diagnosed with bilateral APyC, intact irides and nystagmus. Genetic testing identified the three patients had novel missense mutations in PAX6 - c.128C > T; p...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29756838/magnetic-excitations-across-the-metal-insulator-transition-in-the-pyrochlore-iridate-eu_-2-ir_-2-o_-7
#2
Sae Hwan Chun, Bo Yuan, Diego Casa, Jungho Kim, Chang-Yong Kim, Zhaoming Tian, Yang Qiu, Satoru Nakatsuji, Young-June Kim
We report a resonant inelastic x-ray scattering study of the magnetic excitation spectrum in a highly insulating Eu_{2}Ir_{2}O_{7} single crystal that exhibits a metal-insulator transition at T_{MI}=111(7)  K. A propagating magnon mode with a 20 meV bandwidth and a 28 meV magnon gap is found in the excitation spectrum at 7 K, which is expected in the all-in-all-out magnetically ordered state. This magnetic excitation exhibits substantial softening as the temperature is raised towards T_{MI} and turns into a highly damped excitation in the paramagnetic phase...
April 27, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29722680/decoupling-of-magnetism-and-electric-transport-in-single-crystal-sr-sub-1-x-sub-a-sub-x-sub-sub-2-sub-iro-sub-4-sub-a-ca-or-ba
#3
Hengdi Zhao, Jasminka Terzic, Hao Zheng, Yifei Ni, Yu Zheng, Feng Ye, Pedro Schlottmann, Gang Cao
We report a systematical structural, transport and magnetic study of Ca or Ba doped Sr2IrO4 single crystals. Isoelectronically substituting Ca2+ (up to 15%) or Ba2+ (up to 4%) ion for the Sr2+ ion provides no additional charge carriers but effectively changes the lattice parameters in Sr2IrO4. In particular, 15% Ca doping considerably compresses the c-axis and the unit cell by nearly 0.45% and 1.00 %, respectively. These significant, anisotropic compressions in the lattice parameters conspicuously cause no change in the Néel temperature which remains at 240 K, but drastically reduces the electrical resistivity by up to five orders of magnitude or even precipitates a sharp insulator-to-metal transition at lower temperatures, i...
May 3, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29701606/stability-of-the-antiferromagnetic-state-in-the-electron-doped-iridates
#4
Sayantika Bhowal, Jamshid Moradi Kurdestany, Sashi Satpathy
Iridates such as Sr$_2$IrO$_4$ are of considerable interest owing to the formation of the Mott insulating state driven by a large spin-orbit coupling. However, in contrast to the expectation from the Nagaoka Theorem that a single doped hole or electron destroys the anti-ferromagnetic (AFM) state of the half-filled Hubbard model in the large U limit, the anti-ferromagnetism persists in the doped Iridates for a large dopant concentration beyond half-filling. 
 With a tight-binding description of the relevant J$_{\rm eff}$ = 1/2 states by the third-neighbor ($t_1$, $t_2$, $t_3$, $U$) Hubbard model on the square lattice, we examine the stability of the AFM state to the formation of a spin spiral state...
April 27, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29701286/physiological-characterization-of-ocular-melanosis-affected-canine-melanocytes
#5
Ethan M Dawson-Baglien, Erica L Noland, Dodd G Sledge, Matti Kiupel, Simon M Petersen-Jones
OBJECTIVE: Cairn terriers with ocular melanosis (OM) accumulate large, heavily pigmented melanocytes in the anterior uvea. Darkly pigmented plaques develop within the sclera, leading us to hypothesize that OM uveal melanocytes may have an abnormal migratory capacity. ANIMALS STUDIED: Globes from OM-affected Cairn terriers and unaffected control eyes enucleated for reasons unrelated to this study were used for immunohistochemistry and to culture melanocytes for in vitro cell behavior assays...
April 27, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29688423/distinct-gene-networks-modulate-floral-induction-of-autonomous-maize-and-photoperiod-dependent-teosinte
#6
Mark A A Minow, Luis M Ávila, Katie Turner, Elena Ponzoni, Iride Mascheretti, Forest M Dussault, Lewis Lukens, Vincenzo Rossi, Joseph Colasanti
Temperate maize was domesticated from its tropical ancestor, teosinte. Whereas temperate maize is an autonomous day-neutral plant, teosinte is an obligate short-day plant that requires uninterrupted long nights to induce flowering. Leaf-derived florigenic signals trigger reproductive growth in both teosinte and temperate maize. To study the genetic mechanisms underlying floral inductive pathways in maize and teosinte, mRNA and small RNA genome-wide expression analyses were conducted on leaf tissue from plants that were induced or not induced to flower...
April 24, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29686615/theissenolactone-c-exhibited-ocular-protection-of-endotoxin-induced-uveitis-by-attenuating-ocular-inflammatory-responses-and-glial-activation
#7
Fan-Li Lin, Jau-Der Ho, Yu-Wen Cheng, George C Y Chiou, Jing-Lun Yen, Hung-Ming Chang, Tzong-Huei Lee, George Hsiao
The aim of this study was to investigate the effects of a natural component, theissenolactone C (LC53), on the ocular inflammation of experimental endotoxin-induced uveitis (EIU) and its related mechanisms in microglia. Evaluation of the severity of anterior uveitis indicated that LC53 treatment significantly decreased iridal hyperemia and restored the clinical scores. Additionally, the deficient retina functions of electroretinography were improved by LC53. LC53 significantly reduced levels of tumor necrosis factor (TNF)-α, monocyte chemoattractant protein-1, protein leakage and activation of matrix metalloproteinases in the anterior section during EIU...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29643790/a-case-of-fundus-oculi-albinoticus-diagnosed-as-angelman-syndrome-by-genetic-testing
#8
Yurie Fukiyama, Masahiro Tonari, Junko Matsuo, Hidehiro Oku, Jun Sugasawa, Shuichi Shimakawa, Tohru Ogihara, Nobuhiko Okamoto, Tsunehiko Ikeda
Purpose: To report a case of fundus oculi albinoticus diagnosed as Angelman syndrome (AS) via genetic testing. Case Report: This study reports on a 4-year-old boy. Since he had been having respiratory disturbance since birth, he underwent a complete physical examination to investigate the cause. The results indicated that he had various brain congenital abnormalities, such as a thin corpus callosum, as well as hydronephrosis, an atrial septal defect, and skin similar to patients with fundus oculi albinoticus...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29623638/the-cost-of-patients-with-chronic-kidney-failure-before-dialysis-results-from-the-iride-observational-study
#9
Claudio Jommi, Patrizio Armeni, Margherita Battista, Paolo di Procolo, Giuseppe Conte, Claudio Ronco, Mario Cozzolino, Anna Maria Costanzo, Umberto di Luzio Paparatti, Gabriella Concas, Giuseppe Remuzzi
BACKGROUND: Chronic kidney disease (CKD) is an important public health problem. Most of the evidence on its costs relates to patients receiving dialysis or kidney transplants, which shows that, in these phases, CKD poses a high burden to payers. Less evidence is available on the costs of the predialytic phase. OBJECTIVE: The aim of this study was to estimate the annual cost of patients with CKD not receiving dialysis treatment, using the Italian healthcare system perspective and a prospective approach...
December 4, 2017: PharmacoEconomics open
https://www.readbyqxmd.com/read/29515824/controlled-iris-radiance-in-a-diurnal-fish-looking-at-prey
#10
Nico K Michiels, Victoria C Seeburger, Nadine Kalb, Melissa G Meadows, Nils Anthes, Amalia A Mailli, Colin B Jack
Active sensing using light, or active photolocation, is only known from deep sea and nocturnal fish with chemiluminescent 'search' lights. Bright irides in diurnal fish species have recently been proposed as a potential analogue. Here, we contribute to this discussion by testing whether iris radiance is actively modulated. The focus is on behaviourally controlled iris reflections, called 'ocular sparks'. The triplefin Tripterygion delaisi can alternate between red and blue ocular sparks, allowing us to test the prediction that spark frequency and hue depend on background hue and prey presence...
February 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29509692/a-novel-anti-spoofing-solution-for-iris-recognition-toward-cosmetic-contact-lens-attack-using-spectral-ica-analysis
#11
Sheng-Hsun Hsieh, Yung-Hui Li, Wei Wang, Chung-Hao Tien
In this study, we maneuvered a dual-band spectral imaging system to capture an iridal image from a cosmetic-contact-lens-wearing subject. By using the independent component analysis to separate individual spectral primitives, we successfully distinguished the natural iris texture from the cosmetic contact lens (CCL) pattern, and restored the genuine iris patterns from the CCL-polluted image. Based on a database containing 200 test image pairs from 20 CCL-wearing subjects as the proof of concept, the recognition accuracy (False Rejection Rate: FRR) was improved from FRR = 10...
March 6, 2018: Sensors
https://www.readbyqxmd.com/read/29479143/ocular-lesions-in-leptin-receptor-deficient-medaka-oryzias-latipes
#12
Shin-Ichi Chisada, Ayano Hirako, Akihiko Sugiyama
Ocular lesions in leptin receptor-deficient medaka were examined histopathologically at 10, 28, and 37 weeks post hatching. Leptin receptor-deficient medaka at 28 and 37 weeks old showed hyperglycemia and hypoinsulinemia. Histopathologically, vacuolation, swelling, fragmentation, and liquefaction of the lens fibers and dilatation of the retinal central veins, retinal capillaries, iridal veins and capillaries, and choroidal veins were observed in leptin receptor-deficient medaka at 28 and 37 weeks old. Thinning of the total retina, pigment epithelial layer, layer of rods and cones, outer granular layer, outer plexiform layer, inner granular layer, and inner plexiform layer was observed in leptin receptor-deficient medaka at 28 and 37 weeks compared with in control medaka...
January 2018: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/29446382/a-spin-orbital-entangled-quantum-liquid-on-a-honeycomb-lattice
#13
K Kitagawa, T Takayama, Y Matsumoto, A Kato, R Takano, Y Kishimoto, S Bette, R Dinnebier, G Jackeli, H Takagi
The honeycomb lattice is one of the simplest lattice structures. Electrons and spins on this simple lattice, however, often form exotic phases with non-trivial excitations. Massless Dirac fermions can emerge out of itinerant electrons, as demonstrated experimentally in graphene, and a topological quantum spin liquid with exotic quasiparticles can be realized in spin-1/2 magnets, as proposed theoretically in the Kitaev model. The quantum spin liquid is a long-sought exotic state of matter, in which interacting spins remain quantum-disordered without spontaneous symmetry breaking...
February 14, 2018: Nature
https://www.readbyqxmd.com/read/29353815/the-challenge-of-spin-orbit-tuned-ground-states-in-iridates-a-key-issues-review
#14
Gang Cao, Pedro Schlottmann
Effects of spin-orbit interactions in condensed matter are an important and rapidly evolving topic. Strong competition between spin-orbit, on-site Coulomb and crystalline electric field interactions in iridates drives exotic quantum states that are unique to this group of materials. In particular, the 'J eff   =  ½' Mott state served as an early signal that the combined effect of strong spin-orbit and Coulomb interactions in iridates has unique, intriguing consequences. In this Key Issues Review, we survey some current experimental studies of iridates...
April 2018: Reports on Progress in Physics
https://www.readbyqxmd.com/read/29321361/a-novel-contiguous-deletion-involving-ndp-maob-and-efhc2-gene-in-a-patient-with-familial-norrie-disease-bilateral-blindness-and-leucocoria-without-other-deficits
#15
Bei Jia, Liping Huang, Yaoyu Chen, Siping Liu, Cuihua Chen, Ke Xiong, Lanlin Song, Yulai Zhou, Xinping Yang, Mei Zhong
Contiguous microdeletions of the Norrie disease pseudoglioma (NDP) region on chromosome Xp11.3 have been widely confirmed as contributing to the typical clinical features of Norrie disease (ND). However, the precise relation between genotype and phenotype could vary. The contiguous deletion of NDP and its neighbouring genes, MAOA/B and EFHC2, reportedly leads to syndromic clinical features such as microcephaly, intellectual disability, and epilepsy. Herewe report a novel contiguous microdeletion of the NDP region containing the MAOB and EFHC2 genes,which causes eye defects but no cognitive disability...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29219540/noncollinear-magnetic-structure-and-multipolar-order-in-eu_-2-ir_-2-o_-7
#16
Yilin Wang, Hongming Weng, Liang Fu, Xi Dai
The magnetic properties of the pyrochlore iridate material Eu_{2}Ir_{2}O_{7} (5d^{5}) have been studied based on first principles calculations, where the crystal field splitting Δ, spin-orbit coupling (SOC) λ, and Coulomb interaction U within Ir 5d orbitals all play significant roles. The ground state phase diagram has been obtained with respect to the strength of SOC and Coulomb interaction U, where a stable antiferromagnetic ground state with all-in-all-out (AIAO) spin structure has been found. In addition, another antiferromagnetic state with energy close to AIAO has also been found to be stable...
November 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29218423/early-intraocular-pressure-change-after-peripheral-iridotomy-with-ultralow-fluence-pattern-scanning-laser-and-nd-yag-laser-in-primary-angle-closure-suspect-kowloon-east-pattern-scanning-laser-study-report-no-3
#17
Jeffrey Chi Wang Chan, Bonnie Nga Kwan Choy, Orlando Chia Chieh Chan, Kenneth Kai Wang Li
PURPOSE: Our purpose was to assess the early intraocular pressure (IOP) changes of ultralow fluence laser iridotomy using pattern scanning laser followed by neodymium:yttrium-aluminum-gamet (Nd:YAG) laser. METHODS: This is a prospective interventional study. Thirty-three eyes of 33 adult Chinese primary angle-closure suspect subjects were recruited for prophylactic laser peripheral iridotomy. Sequential laser peripheral iridotomy was performed using pattern scanning laser followed by Nd:YAG laser...
February 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29165421/-outcomes-of-intraocular-lens-implantation-in-the-absence-of-capsular-support-a-review-of-current-literature
#18
A V Gushchin, N V Kadatskaya
Тhe prevalence of complications associated with the deficiency or absence of capsular support in cataract patients is 5-15%. Moreover, approximately 20% of patients have an inconspicuous zonular weakness, which is often left undetected preoperatively. AIM: to classify and comparatively analyze the latest published data on the outcomes of various kinds of complicated cataract surgery. MATERIAL AND METHODS: Analysis of available literature on the subject of research published in 2003-2016...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29157308/characterization-of-the-upper-and-lower-respiratory-tract-microbiota-in-piedmontese-calves
#19
Isabella Nicola, Francesco Cerutti, Elena Grego, Iride Bertone, Paola Gianella, Antonio D'Angelo, Simone Peletto, Claudio Bellino
BACKGROUND: The microbiota of the bovine upper respiratory tract has been recently characterized, but no data for the lower respiratory tract are available. A major health problem in bovine medicine is infectious bronchopneumonia, the most common respiratory syndrome affecting cattle. With this study, we used 16S rRNA gene sequencing to characterize and compare the microbial community composition of the upper and lower respiratory tracts in calves. RESULTS: The microbiota of the upper (nasal swab [NS]) and the lower (trans-tracheal aspiration [TTA]) respiratory tracts of 19 post-weaned Piedmontese calves with (8/19) and without (11/19) clinical signs of respiratory disease, coming from six different farms, was characterized by 16S rRNA gene metabarcoding...
November 21, 2017: Microbiome
https://www.readbyqxmd.com/read/29082081/human-iris-three-dimensional-imaging-at-micron-resolution-by-a-micro-plenoptic-camera
#20
Hao Chen, Maria A Woodward, David T Burke, V Swetha E Jeganathan, Hakan Demirci, Volker Sick
A micro-plenoptic system was designed to capture the three-dimensional (3D) topography of the anterior iris surface by simple single-shot imaging. Within a depth-of-field of 2.4 mm, depth resolution of 10 µm can be achieved with accuracy (systematic errors) and precision (random errors) below 20%. We demonstrated the application of our micro-plenoptic imaging system on two healthy irides, an iris with naevi, and an iris with melanoma. The ridges and folds, with height differences of 10~80 µm, on the healthy irides can be effectively captured...
October 1, 2017: Biomedical Optics Express
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