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Myocardial infarction in women

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https://www.readbyqxmd.com/read/29352072/sex-and-race-differences-in-lifetime-risk-of-heart-failure-with-preserved-ejection-fraction-and-heart-failure-with-reduced-ejection-fraction
#1
Ambarish Pandey, Wally Omar, Colby Ayers, Michael LaMonte, Liviu Klein, Norrina Allen, Lewis H Kuller, Philip Greenland, Charles Eaton, John S Gottdiener, Donald Lloyd-Jones, Jarett D Berry
Background -Lifetime risk of heart failure has been estimated to range from 20% to 46% in diverse sex and race groups. However, lifetime risk estimates for the two HF phenotypes, HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF), is not known. Methods -Participant-level data from 2 large prospective cohort studies, the Cardiovascular Health Study (CHS) and the Multiethnic Study of Atherosclerosis (MESA), were pooled excluding individuals with prevalent HF at baseline...
January 19, 2018: Circulation
https://www.readbyqxmd.com/read/29351624/takotsubo-cardiomyopathy-associated-with-work-place-bullying
#2
Halla Malik, Nadarajah Kangaharan, Ian Agahari
Background: Takotsubo cardiomyopathy (TC) is a condition of transient left ventricular dysfunction precipitated by acute physical or emotional stress. The pathogenesis of TC is not well understood, but it is known to predominantly affect postmenopausal women in the context of physical or emotional triggers. Aims: To describe a case of TC with an association to a never previously described work place stressor of bullying. Case Report: A 48-year-old female lawyer developed acute chest pain after experiencing significant emotional distress at a workplace meeting...
January 17, 2018: Occupational Medicine
https://www.readbyqxmd.com/read/29348194/health-care-costs-associated-with-incident-complications-in-patients-with-type-2-diabetes-in-germany
#3
Katharina Kähm, Michael Laxy, Udo Schneider, Wolf H Rogowski, Stefan K Lhachimi, Rolf Holle
OBJECTIVE: The aim of this study is to provide reliable regression-based estimates of costs associated with different type 2 diabetes complications. RESEARCH DESIGN AND METHODS: We used nationwide statutory health insurance (SHI) data from 316,220 patients with type 2 diabetes. Costs for inpatient and outpatient care, pharmaceuticals, rehabilitation, and nonmedical aids and appliances were assessed in the years 2013-2015. Quarterly observations are available for each year...
January 18, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29344384/blood-pressure-target-achievement-and-antihypertensive-medication-use-in-women-and-men-after-first-ever-myocardial-infarction-the-troms%C3%A3-study-1994-2016
#4
Laila A Hopstock, Anne Elise Eggen, Maja-Lisa Løchen, Ellisiv B Mathiesen, Amalie Nilsen, Inger Njølstad, Tom Wilsgaard
Background: Recurrent cardiovascular events after myocardial infarction (MI) are frequent, and gender differences in blood pressure treatment have been reported. Despite increased focus on secondary prevention, recent reports indicate that treatment targets are not achieved. There is a need for gender-specific analyses of post-MI blood pressure treatment target achievement and antihypertensive medication adherence. Design: We investigated the change in systolic and diastolic blood pressure and antihypertensive drug use after first-ever MI over two time periods in a Norwegian population-based study...
2018: Open Heart
https://www.readbyqxmd.com/read/29340571/comparison-of-physician-visual-assessment-with-quantitative-coronary-angiography-in-assessment-of-stenosis-severity-in-china
#5
Haibo Zhang, Lin Mu, Shuang Hu, Brahmajee K Nallamothu, Alexandra J Lansky, Bo Xu, Georgios Bouras, David J Cohen, John A Spertus, Frederick A Masoudi, Jeptha P Curtis, Runlin Gao, Junbo Ge, Yuejin Yang, Jing Li, Xi Li, Xin Zheng, Yetong Li, Harlan M Krumholz, Lixin Jiang
Importance: Although physician visual assessment (PVA) of stenosis severity is a standard clinical practice to support decisions for coronary revascularization, there are concerns about its accuracy. Objective: To compare PVA with quantitative coronary angiography (QCA) as a means of assessing stenosis severity among patients undergoing percutaneous coronary intervention (PCI) in China. Design, Setting, and Participants: A cross-sectional study (2012-2013) of a random subset of 1295 patients from the China Patient-centered Evaluative Assessment of Cardiac Events (PEACE) Prospective PCI Study was carried out...
January 16, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29331164/adherence-to-the-danish-food-based-dietary-guidelines-and-risk-of-myocardial-infarction-a-cohort-study
#6
Camilla Plambeck Hansen, Kim Overvad, Inge Tetens, Anne Tjønneland, Erik Thorlund Parner, Marianne Uhre Jakobsen, Christina Catherine Dahm
OBJECTIVE: A direct way to evaluate food-based dietary guidelines is to assess if adherence is associated with development of non-communicable diseases. Thus, the objective was to develop an index to assess adherence to the 2013 Danish food-based dietary guidelines and to investigate the association between adherence to the index and risk of myocardial infarction (MI). DESIGN: Population-based cohort study with recruitment of participants in 1993-1997. Information on dietary intake was collected at baseline using an FFQ and an index ranging from 0 to 6 points was created to assess adherence to the 2013 Danish food-based dietary guidelines...
January 14, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#7
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29328029/-metabolic-secretion-in-reproductive-age-women-with-obesity
#8
A Malazonia, T Zerekidze, N Vekua, N Chkheidze, K Asatiani
For the last decade melatonin has attracted attention as a neuroregulator in pathogenesis of obesity and metabolic syndrome. The aim of our study is to evaluate the characteristics of metabolic secretion in obese women of reproductive age. The study was conducted on the total number of 120 women. Eighty women with obesity formed the case group, and forty healthy women - the control group. Carbohydrate metabolism, lipid profile and serum levels of melatonin were evaluated in all study subjects. According to the results, 61...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29327149/gestational-diabetes-and-risk-of-cardiovascular-disease-up-to-25%C3%A2-years-after-pregnancy-a-retrospective-cohort-study
#9
Safyer McKenzie-Sampson, Gilles Paradis, Jessica Healy-Profitós, Frédérique St-Pierre, Nathalie Auger
AIMS: The risk of cardiovascular disease in women with gestational diabetes is poorly understood. We sought to determine whether gestational diabetes increases the risk of cardiovascular disease more than two decades after pregnancy. METHODS: We carried out a retrospective cohort study of 1,070,667 women who delivered infants in hospitals within Quebec, Canada, between 1989 and 2013. We followed 67,356 women with gestational diabetes and 1,003,311 without gestational diabetes for a maximum of 25...
January 11, 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29326108/short-term-risk-of-cardiovascular-readmission-following-a-hypertensive-disorder-of-pregnancy
#10
Jennifer L Jarvie, Torri D Metz, Melinda B Davis, Jessica C Ehrig, David P Kao
OBJECTIVE: Women with pregnancies complicated by hypertensive disorders of pregnancy (HDP) have increased long-term cardiovascular (CV) risk. We sought to determine if they demonstrate increased short-term CV risk. METHODS: Using administrative records, all hospital-based deliveries in Florida from 2004 to 2010 and subsequent readmission to any Florida hospital within 3 years of index delivery were identified. Deliveries and clinical diagnoses were determined using International Classification of Diseases, Ninth Revision, Clinical Modification codes...
January 11, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29324812/identifying-unmet-clinical-need-in-hypertrophic-cardiomyopathy-using-national-electronic-health-records
#11
Mar Pujades-Rodriguez, Oliver P Guttmann, Arturo Gonzalez-Izquierdo, Bram Duyx, Constantinos O'Mahony, Perry Elliott, Harry Hemingway
INTRODUCTION: To evaluate unmet clinical need in unselected hypertrophic cardiomyopathy (HCM) patients to determine the risk of a wide range of subsequent cardiovascular disease endpoints and safety endpoints relevant for trial design. METHODS: Population based cohort (CALIBER, linked primary care, hospital and mortality records in England, period 1997-2010), all people diagnosed with HCM were identified and matched by age, sex and general practice with ten randomly selected people without HCM...
2018: PloS One
https://www.readbyqxmd.com/read/29322612/validation-of-contemporary-risk-scores-in-predicting-coronary-thrombotic-events-and-major-bleeding-in-patients-with-acute-coronary-syndrome-after-drug-eluting-stent-implantations
#12
Li Song, Changdong Guan, Hongbing Yan, Shubin Qiao, Yongjian Wu, Jinqing Yuan, Kefei Dou, Yuejin Yang, George D Dangas, Bo Xu
OBJECTIVES: We aimed to assess the prognostic ability of the ST score, DAPT score, and PARIS score in a Chinese population. BACKGROUND: Recently, several risk scores predicting the long-term risk of coronary thrombotic events [CTE, defined as the composite of definite or probable stent thrombosis (ST) and myocardial infarction] and bleeding have been developed and initially validated in Western populations. METHODS: A total of 6,088 consecutive patients with acute coronary syndrome (mean age 58...
January 11, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29322167/use-of-high-risk-coronary-atherosclerotic-plaque-detection-for-risk-stratification-of-patients-with-stable-chest-pain-a-secondary-analysis-of-the-promise-randomized-clinical-trial
#13
Maros Ferencik, Thomas Mayrhofer, Daniel O Bittner, Hamed Emami, Stefan B Puchner, Michael T Lu, Nandini M Meyersohn, Alexander V Ivanov, Elizabeth C Adami, Manesh R Patel, Daniel B Mark, James E Udelson, Kerry L Lee, Pamela S Douglas, Udo Hoffmann
Importance: Coronary computed tomographic angiography (coronary CTA) can characterize coronary artery disease, including high-risk plaque. A noninvasive method of identifying high-risk plaque before major adverse cardiovascular events (MACE) could provide practice-changing optimizations in coronary artery disease care. Objective: To determine whether high-risk plaque detected by coronary CTA was associated with incident MACE independently of significant stenosis (SS) and cardiovascular risk factors...
January 10, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29321430/new-onset-takayasu-s-arteritis-as-acute-myocardial-infarction
#14
Yusuke Ishiyama, Kazuo Eguchi, Katsuaki Yokota, Tomokazu Ikemoto, Kazuomi Kario
We herein report the case of a 25-year-old Japanese woman with left-main-trunk acute myocardial infarction (LMT-AMI). She had cardiogenic shock, so emergency percutaneous intervention was performed. Intravascular ultrasound of LMT-AMI showed that the three-layered structure of the intima, tunica media, and adventitia was not clearly visible, and the vessel was concentrically thickened; unstable plaque and calcification were not seen. AMI is rarely seen in young women, but Takayasu's arteritis is one major cause...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29319393/sex-based-differences-in-discharge-disposition-and-outcomes-for-st-segment-elevation-myocardial-infarction-patients-within-a-regional-network
#15
James R Langabeer, Timothy D Henry, Raymond Fowler, Tiffany Champagne-Langabeer, Junghyun Kim, Alice K Jacobs
BACKGROUND: It is known that women with ST-segment elevation myocardial infarction (STEMI) have higher mortality in comparison to men. While the reasons for this sex-based difference are not completely understood, biologic differences and disparities in care have been implicated. Whether these differences persist within an urban, regional STEMI system of care with defined protocols is unclear. Our objective was to explore sex-related effects in outcomes in a large regional system of care...
January 10, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29316329/rapid-and-safe-discharge-from-the-emergency-department-a-single-troponin-to-exclude-acute-myocardial-infarction
#16
Lisa Brichko, Hans G Schneider, William Chan, Jarrel Seah, De Villiers Smit, Anthony Dart, Jeremy P Stevens, Biswadev Mitra
OBJECTIVE: To determine variables that could facilitate safe discharge from the ED following a single high-sensitivity troponin I (HsTnI) result to exclude acute myocardial infarction (AMI). METHODS: A retrospective cohort study was performed at a tertiary hospital of all patients that had serial HsTnI performed within 12 h of arrival to the ED over a 3 year period. The primary exposure variable of interest was a very low troponin initial result (HsTnI <5 ng/L)...
January 8, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29314248/calcium-and-vitamin-d-supplementation-are-not-associated-with-risk-of-incident-ischaemic-cardiac-events-or-death-findings-from-the-uk-biobank-cohort
#17
Nicholas C Harvey, Stefania D'Angelo, Julien Paccou, Elizabeth M Curtis, Mark Edwards, Zahra Raisi-Estabragh, Karen Walker-Bone, Steffen E Petersen, Cyrus Cooper
We investigated associations between calcium/vitamin D supplementation and incident cardiovascular events/deaths in a UK population-based cohort. UK Biobank is a large prospective cohort comprising 502,637 men and women aged 40-69 years at recruitment. Supplementation with calcium/vitamin D was self-reported, and information on incident hospital admission (ICD-10) for ischaemic heart disease (IHD), myocardial infarction (MI) any cardiovascular event, and subsequent death, was obtained from linkage to national registers...
January 4, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29311289/contemporary-sex-based-differences-by-age-in-presenting-characteristics-use-of-an-early-invasive-strategy-and-inhospital-mortality-in-patients-with-non-st-segment-elevation-myocardial-infarction-in-the-united-states
#18
Tanush Gupta, Dhaval Kolte, Sahil Khera, Nayan Agarwal, Pedro A Villablanca, Kashish Goel, Kavisha Patel, Wilbert S Aronow, Jose Wiley, Anna E Bortnick, Herbert D Aronow, J Dawn Abbott, Robert T Pyo, Julio A Panza, Mark A Menegus, Charanjit S Rihal, Gregg C Fonarow, Mario J Garcia, Deepak L Bhatt
BACKGROUND: Prior studies have reported higher inhospital mortality in women versus men with non-ST-segment-elevation myocardial infarction. Whether this is because of worse baseline risk profile compared with men or sex-based disparities in treatment is not completely understood. METHODS AND RESULTS: We queried the 2003 to 2014 National Inpatient Sample databases to identify all hospitalizations in patients aged ≥18 years with the principal diagnosis of non-ST-segment-elevation myocardial infarction...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29311155/increased-risk-of-severe-hypoglycemic-events-before-and-after-cardiovascular-outcomes-in-tecos-suggests-an-at-risk-type-2-diabetes-frail-patient-phenotype
#19
Eberhard Standl, Susanna R Stevens, Paul W Armstrong, John B Buse, Juliana C N Chan, Jennifer B Green, John M Lachin, Andre Scheen, Florence Travert, Frans Van de Werf, Eric D Peterson, Rury R Holman
OBJECTIVE: Severe hypoglycemic events (SHEs) in type 2 diabetes are associated with subsequent cardiovascular (CV) event risk. We examined whether CV events were associated with subsequent SHE risk. RESEARCH DESIGN AND METHODS: Time-dependent associations between SHEs and a composite CV end point (fatal/nonfatal myocardial infarction or stroke, hospitalization for unstable angina, hospitalization for heart failure [hHF]) were examined post hoc in 14,671 TECOS (Trial Evaluating Cardiovascular Outcomes With Sitagliptin) participants with type 2 diabetes and CV disease followed for a median of 3...
January 8, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29310674/ezetimibe-prescriptions-in-older-canadian-adults-after-an-acute-myocardial-infarction-a-population-based-cohort-study
#20
Kristin K Clemens, Salimah Z Shariff, Eric McArthur, Robert A Hegele
BACKGROUND: The utility of ezetimibe in preventing cardiovascular outcomes remains controversial. To guide future assessments of the effectiveness of ezetimibe in routine care, we evaluated how this medication has been prescribed to high-risk older adults in Ontario, Canada. METHODS: Using linked healthcare databases, we carried out a population-based cohort study of older adults who were discharged from hospital following an acute myocardial infarction from 2005 until 2014...
January 8, 2018: Lipids in Health and Disease
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