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Myocardial infarction in women

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https://www.readbyqxmd.com/read/28807713/opioid-drug-use-and-acute-cardiac-events-among-pregnant-women-in-the-united-states
#1
Hamisu M Salihu, Jason L Salemi, Anjali Aggarwal, Beverly F Steele, Ross C Pepper, Mulubrhan F Mogos, Muktar H Aliyu
BACKGROUND: Cardiovascular disease remains a leading cause of pregnancy-associated deaths in the United States (US). The extent to which increasing opioid use among pregnant women contributes to fatal cardiovascular events is unknown. We examine trends in opioid use among pregnant women over the previous decade, and the association between changes in temporal trends in opioid drug use and the incidence of acute cardiac events among mothers. METHODS: In this retrospective analysis of the Healthcare and Cost Utilization Project (HCUP), we utilized a two-stage stratified cluster sampling of all inpatient hospital discharges from non-federal hospitals between 01/01/2002 through 12/31/2014...
August 11, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28801280/-regression-analysis-of-red-cell-distribution-width-and-mean-platelet-volume-in-patients-with-acute-myocardial-infarction
#2
Qi Liang, Xin-Jun Lei, Hong-Bing Li, Yang-Rong Yin, Jie Ren, Li-Hong Fan, Xin Huang, Zu-Yi Yuan
OBJECTIVE: To investigate clinical implications of changes in red cell distribution width (RDW) and mean platelet volume (MPV) in patients with acute myocardial infarction. METHODS: A total of 127 patients (90 men and 37 women) were enrolled in this analysis, including 66 with acute myocardial infarction (AMI) and 61 with unstable angina (UA). The patients' baseline demographic and clinical data were compared between the two groups including age, hypertension, diabetes, smoking, BMI, blood biochemical profiles, cardiac functions and platelet and red blood cell parameters...
August 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28801278/-a-rare-case-of-spontaneous-coronary-artery-dissection-after-emotional-stress-in-a-postmenopausal-woman
#3
Yuan DU, Ke Han, Ling Bai, Ping Liu
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute myocardial infarction. While its etiology and pathogenesis remain not fully understood, SCAD occurs most frequently in patients at a young age and of a female gender. We report a case of SCAD in a 52-year-old healthy postmenopausal woman who developed acute myocardial infarction and subsequent ventricular aneurysm after emotional stress. This case may provide valuable insight into this rare disease and highlights the importance of psychological factors as contributing factors of SCAD in postmenopausal women with acute onset of chest pain...
August 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28799038/association-of-lead-exposure-with-cardiovascular-risk-factors-and-diseases-in-chinese-adults
#4
Chi Chen, Qin Li, Xiaomin Nie, Bing Han, Yi Chen, Fangzhen Xia, Hualing Zhai, Ningjian Wang, Yingli Lu
We aimed to determine whether lead exposure was associated with cardiovascular diseases (CVD) and risk factors in Chinese adults. Five thousand three hundred and forty-eight subjects were enrolled from 16 sites in China. Blood lead level (BLL) was measured by atomic absorption spectrometry. Cardiovascular diseases included coronary heart disease, stroke, and myocardial infarction. Cardiovascular risk factors included body mass index (BMI), fasting plasma glucose (FPG), lipid profile, and blood pressure. We found that 5...
August 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28798780/gender-related-differences-in-long-term-outcome-among-high-risk-patients-with-myocardial-infarction-treated-invasively
#5
Julita Sarek, Anita Paczkowska, Bartosz Wilczyński, Paweł Francuz, Tomasz Podolecki, Radosław Lenarczyk, Beata Średniawa, Zbigniew Kalarus, Jacek Kowalczyk
INTRODUCTION: Treating acute myocardial infarction (AMI) with percutaneous coronary intervention (PCI) has an impact on improving long-term outcome. However, patients with other comorbidities are challenging, and are considered as a high-risk population. AIM: To assess gender-related differences in long-term prognosis after AMI among high-risk patients. MATERIAL AND METHODS: The single-center registry encompassed 4375 AMI patients treated with PCI...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/28797259/gender-differences-in-hospital-admissions-for-major-cardiovascular-events-and-procedures-in-people-with-and-without-diabetes-in-england-a-nationwide-study-2004-2014
#6
Anthony A Laverty, Alex Bottle, Sung-Hee Kim, Bhakti Visani, Azeem Majeed, Christopher Millett, Eszter P Vamos
BACKGROUND: Secondary prevention of cardiovascular disease (CVD) has improved immensely during the past decade but controversies persist on cardiovascular benefits among women with diabetes. We investigated 11-year trends in hospital admission rates for acute myocardial infarction (AMI), stroke, percutaneous coronary intervention (PCI), and coronary artery bypass graft (CABG) in people with and without diabetes by gender in England. METHODS: We identified all hospital admissions for cardiovascular disease causes among people aged 17 years and above between 2004 and 2014 in England...
August 10, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28796809/a-randomized-multicenter-trial-comparing-the-xience-everolimus-eluting-stent-with-the-cypher-sirolimus-eluting-stent-in-the-treatment-of-female-patients-with-de-novo-coronary-artery-lesions-the-spirit-women-study
#7
Anna Franzone, Serge Zaugg, Raffaele Piccolo, Maria Grazia Modena, Ghada W Mikhail, Josepa Mauri Ferré, Ruth Strasser, Liliana Grinfeld, Dik Heg, Peter Jüni, Stephan Windecker, Marie-Claude Morice
BACKGROUND: The comparative performance of different drug-eluting stents (DES) among female patients has not been assessed in a randomized manner. OBJECTIVES: The SPIRIT Women Clinical Evaluation trial compared the durable polymer everolimus-eluting XIENCE stent (DP-EES) with the durable polymer sirolimus-eluting Cypher stent (DP-SES) in women undergoing percutaneous coronary intervention (PCI). METHODS: A total of 455 female patients with stable CAD were randomly assigned to receive DP-EES (n = 304) or DP-SES (n = 151)...
2017: PloS One
https://www.readbyqxmd.com/read/28794619/grip-strength-as-a-frailty-diagnostic-component-in-geriatric-inpatients
#8
Joanna Dudzińska-Griszek, Karolina Szuster, Jan Szewieczek
BACKGROUND: Frailty has emerged as a key medical syndrome predictive of comorbidity, disability, institutionalization and death. As a component of the five frailty phenotype diagnostic criteria, patient grip strength deserves attention as a simple and objective measure of the frailty syndrome. The aim of this study was to assess conditions that influence grip strength in geriatric inpatients. PATIENTS AND METHODS: The study group consisted of 80 patients aged 78...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28794105/left-ventricular-diastolic-dysfunction-in-women-with-non-obstructive-ischemic-heart-disease-insights-from-magnetic-resonance-imaging-and-spectroscopy
#9
Michael D Nelson
Ischemic Heart Disease, in the absence of obstructive coronary artery disease, is prevalent in women, and constitutes a major risk factor for developing major adverse cardiovascular events, including myocardial infarction, stroke, and heart failure. For decades, diagnosis was considered benign and often minimized; however, it is now known that this etiology caries much risk and is a significant burden to the health care system. This review summarizes the current state-of-knowledge on non-obstructive ischemic heart disease (NOIHD), the association between NOIHD and left ventricular diastolic dysfunction, potential links between NOIHD and the development of heart failure with preserved ejection fraction (HFpEF), and therapeutic options and knowledge gaps for patients living with NOIHD...
August 9, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28791827/correlation-between-the-state-of-periodontal-tissues-and-selected-risk-factors-for-periodontitis-and-myocardial-infarction
#10
Renata Górska, Elżbieta Dembowska, Tomasz P Konopka, Joanna Wysokińska-Miszczuk, Małgorzata Pietruska, Ewa Ganowicz
BACKGROUND: The current level of knowledge indicates a relationship between periodontitis and diabetes and/or cardiovascular diseases (CVD). Periodontitis can be not only a risk factor for these diseases, but also a condition modifying other primary risk factors associated with the occurrence of cardiovascular complications (lipid disorders, arterial hypertension, etc.) or diabetes. OBJECTIVES: The aim of the study was an analysis of the correlation between the state of periodontal tissues and selected risk factors for myocardial infarction (MI) in patients after recent myocardial infarction...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790123/prognostic-significance-of-nonobstructive-left-main-coronary-artery-disease-in-women-versus-men-long-term-outcomes-from-the-confirm-coronary-ct-angiography-evaluation-for-clinical-outcomes-an-international-multicenter-registry
#11
Joe X Xie, Parham Eshtehardi, Tina Varghese, Abhinav Goyal, Puja K Mehta, William Kang, Jonathon Leipsic, Bríain Ó Hartaigh, C Noel Bairey Merz, Daniel S Berman, Heidi Gransar, Matthew J Budoff, Stephan Achenbach, Tracy Q Callister, Hugo Marques, Ronen Rubinshtein, Mouaz H Al-Mallah, Daniele Andreini, Gianluca Pontone, Filippo Cademartiri, Erica Maffei, Kavitha Chinnaiyan, Gilbert Raff, Martin Hadamitzky, Joerg Hausleiter, Gudrun Feuchtner, Philipp A Kaufmann, Todd C Villines, Benjamin J W Chow, James K Min, Leslee J Shaw
BACKGROUND: Patients with obstructive (≥50% stenosis) left main (LM) coronary artery disease (CAD) are at high risk for adverse events; prior studies have also documented worse outcomes among women than men with severe multivessel/LM CAD. However, the prognostic significance of nonobstructive (1%-49% stenosis) LM CAD, including sex-specific differences, has not been previously examined. METHODS AND RESULTS: In the long-term CONFIRM (Coronary CT Angiography Evaluation For Clinical Outcomes: An International Multicenter) registry, patients underwent elective coronary computed tomographic angiography for suspected CAD and were followed for 5 years...
August 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28781064/cardiovascular-mortality-and-morbidity-in-patients-with-type-2-diabetes-following-initiation-of-sodium-glucose-co-transporter-2-inhibitors-versus-other-glucose-lowering-drugs-cvd-real-nordic-a-multinational-observational-analysis
#12
Kåre I Birkeland, Marit E Jørgensen, Bendix Carstensen, Frederik Persson, Hanne L Gulseth, Marcus Thuresson, Peter Fenici, David Nathanson, Thomas Nyström, Jan W Eriksson, Johan Bodegård, Anna Norhammar
BACKGROUND: In patients with type 2 diabetes and a high cardiovascular risk profile, the sodium-glucose co-transporter-2 (SGLT2) inhibitors empagliflozin and canagliflozin have been shown to lower cardiovascular morbidity and mortality. Using real-world data from clinical practice, we aimed to compare cardiovascular mortality and morbidity in new users of SGLT2 inhibitors versus new users of other glucose-lowering drugs, in a population with a broad cardiovascular risk profile. METHODS: CVD-REAL Nordic was an observational analysis of individual patient-level data from the Prescribed Drug Registers, Cause of Death Registers, and National Patient Registers in Denmark, Norway, and Sweden...
August 3, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28781027/tobacco-exposure-as-determined-by-serum-cotinine-and-subclinical-myocardial-injury-in-individuals-free-from-cardiovascular-disease
#13
Muhammad Ali, Yabing Li, Wesley T O'Neal, Elsayed Z Soliman
Tobacco exposure including second-hand smoke is the leading preventable cause of premature death in the United States. Serum cotinine, a highly sensitive and specific biomarker for tobacco exposure, is a more accurate measure of tobacco exposure than self-reported smoking status. Although the harmful effect of tobacco exposure on cardiovascular disease (CVD) risk factors (e.g., atherosclerosis) or hard CVD outcomes (e.g., myocardial infarction) is well established, its effect on intermediate outcomes such as subclinical myocardial injury (SMI), especially in nonsmokers, is not clear...
July 14, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28781023/comparison-of-30-day-readmission-rates-after-hospitalization-for-acute-myocardial-infarction-in-men-versus-women
#14
Cashel O'Brien, Linda Valsdottir, Jason H Wasfy, Jordan B Strom, Eric A Secemsky, Yun Wang, Robert W Yeh
Readmission after hospitalization for acute myocardial infarction (AMI) significantly contributes to preventable morbidity and health-care costs. Outcomes after AMI vary by sex but the relationship of sex to readmissions warrants further exploration. Using the 2013 Nationwide Readmissions Database, we identified patients with a principal discharge diagnosis of AMI and stratified all-cause 30-day readmissions by sex and age. Of 214,824 patients, 44% were 18 to 64 years of age, 56% were ≥65 years, and 28% and 45%, respectively, were female...
July 14, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28780661/unique-presentations-and-etiologies-of-myocardial-infarction-in-women
#15
REVIEW
Marysia S Tweet, Patricia Best, Sharonne N Hayes
Despite recent efforts to reduce cardiovascular disease, it remains the leading cause of morbidity and mortality among women, particularly younger women. When compared to men, women have more inpatient complications, mortality, heart failure, and stroke following acute myocardial infarction (AMI) despite having less obstructive coronary artery disease. Moreover, women are less likely to have AMI from plaque rupture than men, and more likely to experience alternate etiologies of AMI including plaque erosion and spontaneous coronary artery dissection...
September 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28777117/delays-in-treatment-seeking-decisions-among-women-with-myocardial-infarction
#16
Cynthia Arslanian-Engoren, Linda D Scott
BACKGROUND: Minimizing the time from myocardial infarction (MI) symptom onset to the implementation of lifesaving interventions decreases morbidity and mortality of women who experience an MI. However, not all women seek timely evaluation and treatment for their MI symptoms. OBJECTIVES: The aim of this article is to describe reasons for decision treatment delays among women who experience an initial MI. METHOD: A secondary analysis of narrative data collected as part of a qualitative study examining the triage experiences of women (N = 14) who presented to the emergency department with symptoms of acute MI...
September 2017: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/28776263/age-and-ischemia-differentially-impact-mitochondrial-ultrastructure-and-function-in-a-novel-model-of-age-associated-estrogen-deficiency-in-the-female-rat-heart
#17
Alexandra M Garvin, Nicole C Aurigemma, Jenna L Hackenberger, Donna H Korzick
Altered mitochondrial respiration, morphology, and quality control collectively contribute to mitochondrial dysfunction in the aged heart. Because myocardial infarction remains the leading cause of death in aged women, the present study utilized a novel rodent model to recapitulate human menopause to interrogate the combination of age and estrogen deficiency on mitochondrial ultrastructure and function with cardiac ischemia/reperfusion (I/R) injury. Female F344 rats were ovariectomized (OVX) at 15 months and studied at 24 months (MO OVX; n = 40) vs adult ovary intact (6 months; n = 41)...
August 4, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28775115/association-of-concentric-left-ventricular-hypertrophy-with-subsequent-change-in-left-ventricular-end-diastolic-volume-the-dallas-heart-study
#18
Sonia Garg, James A de Lemos, Susan A Matulevicius, Colby Ayers, Ambarish Pandey, Ian J Neeland, Jarett D Berry, Roderick McColl, Christopher Maroules, Ronald M Peshock, Mark H Drazner
BACKGROUND: In the conventional paradigm of the progression of left ventricular hypertrophy, a thick-walled left ventricle (LV) ultimately transitions to a dilated cardiomyopathy. There are scant data in humans demonstrating whether this transition occurs commonly without an interval myocardial infarction. METHODS AND RESULTS: Participants (n=1282) from the Dallas Heart Study underwent serial cardiac magnetic resonance ≈7 years apart. Those with interval cardiovascular events and a dilated LV (increased LV end-diastolic volume [EDV] indexed to body surface area) at baseline were excluded...
August 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28774633/trends-in-hospitalization-and-mortality-rates-due-to-acute-cardiovascular-disease-in-castile-and-le%C3%A3-n-2001-to-2015
#19
Juan B López-Messa, Jesús M Andrés-de Llano, Laura López-Fernández, Jesús García-Cruces, Julio García-Crespo, Miryam Prieto González
INTRODUCTION AND OBJECTIVES: To analyze hospitalization and mortality rates due to acute cardiovascular disease (ACVD). METHODS: We conducted a cross-sectional study of the hospital discharge database of Castile and León from 2001 to 2015, selecting patients with a principal discharge diagnosis of acute myocardial infarction (AMI), unstable angina, heart failure, or acute ischemic stroke (AIS). Trends in the rates of hospitalization/100 000 inhabitants/y and hospital mortality/1000 hospitalizations/y, overall and by sex, were studied by joinpoint regression analysis...
July 31, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28766924/factors-associated-with-performing-urgent-coronary-angiography-in-out-of-hospital-cardiac-arrest-patients
#20
David H Lam, Lauren M Glassmoyer, Jordan B Strom, Roger B Davis, James M McCabe, Donald E Cutlip, Michael W Donnino, Michael N Cocchi, Duane S Pinto
OBJECTIVES: Factors associated with performing urgent coronary angiography (UCA) in patients with out-of-hospital cardiac arrest (OHCA) were identified. BACKGROUND: Current guidelines for resuscitated OHCA patients recommend UCA if there is ST-elevation on post-arrest electrocardiogram or high suspicion of acute myocardial infarction. Some have advocated for UCA in all OHCA regardless of suspected etiology. The reasons for variations in performing UCA are not well understood...
August 2, 2017: Catheterization and Cardiovascular Interventions
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