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https://www.readbyqxmd.com/read/29331099/adaptation-and-validation-of-the-disruptive-behaviour-disorders-teacher-rating-scale-as-a-screening-tool-for-early-detection-of-disruptive-behaviour-disorders-in-schools-in-a-lower-middle-income-setting
#1
Olawunmi Olagundoye, Alex Igundunasse, Morenike Aluko
Background Despite the need to curb the menace resulting from the negative trajectory of disruptive behaviour disorders (DBD) in societies of the world today, there is yet a dearth of locally standardised tools for the early detection of these disorders in Nigeria. This study was aimed at standardising the DBD teacher rating scale (DBD-TRS) to be culturally specific using teachers' ratings of their students. Objectives To establish norm scores for the three categories of DBD on the DBD-TRS, to evaluate the reliability, validity, predictive power, sensitivity and specificity of DBD-TRS items for identifying DBD symptoms amongst children/adolescents between the ages of 4 and 16 years...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29330007/lost-connections-oxytocin-and-the-neural-physiological-and-behavioral-consequences-of-disrupted-relationships
#2
REVIEW
Tobias T Pohl, Larry J Young, Oliver J Bosch
In humans and rodent animal models, the brain oxytocin system is paramount for facilitating social bonds, from the formation and consequences of early-life parent-infant bonds to adult pair bond relationships. In social species, oxytocin also mediates the positive effects of healthy social bonds on the partners' well-being. However, new evidence suggests that the negative consequences of early neglect or partner loss may be mediated by disruptions in the oxytocin system as well. With a focus on oxytocin and its receptor, we review studies from humans and animal models, i...
January 9, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29325518/experiences-of-gestational-diabetes-and-gestational-diabetes-care-a-focus-group-and-interview-study
#3
Judith Parsons, Katherine Sparrow, Khalida Ismail, Katharine Hunt, Helen Rogers, Angus Forbes
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy. It is associated with adverse fetal, infant and maternal outcomes, as well as an increased risk of GDM in future pregnancies and type 2 diabetes for both mother and offspring. Previous studies have shown that GDM can result in an emotionally distressing pregnancy, but there is little research on the patient experience of GDM care, especially of a demographically diverse UK population. The aim of this research was to explore the experiences of GDM and GDM care for a group of women attending a large diabetes pregnancy unit in southeast London, UK, in order to improve care...
January 11, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29325468/does-enhanced-support-for-offenders-effectively-reduce-custodial-violence-and-disruption-an-evaluation-of-the-enhanced-support-service-pilot
#4
Jake Camp, Kerry Joy, Mark Freestone
This study aimed to examine the effectiveness of The Enhanced Support Service (ESS) pilot in reducing custodial violence and disruption, and the associated costs, by observing the behavioural change of the 35 service users who participated in ESS intervention within its first 22 months of operation. Frequencies of recorded incidents of aggressive behaviours, self-harming behaviours, noncompliance, and positive behaviours were counted from routine administrative systems using a coding structure developed in previous studies...
January 1, 2018: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29321841/reversed-gender-ratio-of-autism-spectrum-disorder-in-smith-magenis-syndrome
#5
Heidi Elisabeth Nag, Ann Nordgren, Britt-Marie Anderlid, Terje Nærland
Background: A substantial amount of research shows a higher rate of autistic type of problems in males compared to females. The 4:1 male to female ratio is one of the most consistent findings in autism spectrum disorder (ASD).Lately, the interest in studying ASD in genetic disorders has increased, and research has shown a higher prevalence of ASD in some genetic disorders than in the general population.Smith-Magenis syndrome (SMS) is a rare and complex genetic syndrome caused by an interstitial deletion of chromosome 17p11...
2018: Molecular Autism
https://www.readbyqxmd.com/read/29306521/what-can-autism-teach-us-about-the-role-of-sensorimotor-systems-in-higher-cognition-new-clues-from-studies-on-language-action-semantics-and-abstract-emotional-concept-processing
#6
REVIEW
Rachel L Moseley, Friedemann Pulvermüller
Within the neurocognitive literature there is much debate about the role of the motor system in language, social communication and conceptual processing. We suggest, here, that autism spectrum conditions (ASC) may afford an excellent test case for investigating and evaluating contemporary neurocognitive models, most notably a neurobiological theory of action perception integration where widely-distributed cell assemblies linking neurons in action and perceptual brain regions act as the building blocks of many higher cognitive functions...
December 7, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29295655/-not-tonight-zebrafish-the-effects-of-ruta-graveolens-on-reproduction
#7
Mohammad Navid Forsatkar, Maryam HedayatiRad, Ana Carolina Luchiari
CONTEXT: There is growing interest in the pharmacological evaluation of Rue due to its potential to treat a variety of clinical diseases. The plant seems to present potent endocrine disrupting effects, and its excretion and disposal are not a concern. OBJECTIVE: The effects of Ruta graveolens L. (Rutaceae) ethanol extract (RE) on reproductive behaviour, fertility, and steroid and thyroid hormone levels in zebrafish were investigated. MATERIAL AND METHODS: We exposed subjects to varying concentrations of RE, and one-tenth the LC50 concentration (2...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29291476/neurodevelopmental-disorders-in-prison-inmates-comorbidity-and-combined-associations-with-psychiatric-symptoms-and-behavioural-disturbance
#8
Susan Young, Rafael A González, Hannah Mullens, Laura Mutch, Isabella Malet-Lambert, Gisli H Gudjonsson
The identification and management of inmates with neurodevelopmental disorders (ND) has been insufficiently addressed in the literature. We estimated the proportion of cases with Attention deficit/hyperactivity disorder (ADHD), Autism spectrum disorder (ASD) and Intellectual disability (ID) in prison, their comorbidity, and associations with disruptive behaviours and with psychiatric symptoms. Further, we examined the role of coexisting ND on psychiatric symptoms and attitudes toward violence. All 390 male inmates underwent an assessment that included the Diagnostic Interview for ADHD in Adults 2...
December 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29280501/-just-because-a-doctor-says-something-doesn-t-mean-that-it-will-happen-self-perception-as-having-a-fertility-problem-among-infertility-patients
#9
Ophra Leyser-Whalen, Arthur L Greil, Julia McQuillan, Katherine M Johnson, Karina M Shrefffler
Only some individuals who have the medically defined condition 'infertility' adopt a self-definition as having a fertility problem, which has implications for social and behavioural responses, yet there is no clear consensus on why some people and not others adopt a medical label. We use interview data from 28 women and men who sought medical infertility treatment to understand variations in self-identification. Results highlight the importance of identity disruption for understanding the dialectical relationship between medical contact and self-identification, as well as how diagnosis acts both as a category and a process...
December 27, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29277599/evolution-of-mate-finding-allee-effect-in-prey
#10
Luděk Berec, Veronika Bernhauerová, Barbara Boldin
The search for mates is often accompanied with conspicuous behaviour or morphology that can be exploited by predators. Here we explore the evolutionary consequences of a trade-off that arises naturally between mate acquisition and risk of predation and study evolution of the rate at which male prey search for mates in a population subject to a mate-finding Allee effect and exposed to either generalist or specialist predators. Since we show that the mate search rate determines the strength of the mate-finding Allee effect, we can alternatively view this as evolution of the mate-finding Allee effect in prey...
December 22, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29274752/chronic-paroxetine-treatment-prevents-disruption-of-methamphetamine-sensitive-circadian-oscillator-in-a-transgenic-mouse-model-of-huntington-s-disease
#11
Koliane Ouk, Juliet Aungier, Marc Cuesta, A Jennifer Morton
Circadian abnormalities seen in Huntington's disease (HD) patients are recapitulated in several HD transgenic mouse models. In mice, alongside the master clock located in the suprachiasmatic nucleus (SCN), two other oscillators may influence circadian behaviour. These are the food-entrainable oscillator (FEO) and the methamphetamine-sensitive circadian oscillator (MASCO). SCN- and MASCO- (but not FEO-) driven rhythms are progressively disrupted in the R6/2 mouse model of HD. MASCO-driven rhythms are induced by chronic treatment with low dose of methamphetamine and characterised by an increase in period length to greater than 24 h...
December 21, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29242594/automated-tracking-to-measure-behavioural-changes-in-pigs-for-health-and-welfare-monitoring
#12
Stephen G Matthews, Amy L Miller, Thomas PlÖtz, Ilias Kyriazakis
Since animals express their internal state through behaviour, changes in said behaviour may be used to detect early signs of problems, such as in animal health. Continuous observation of livestock by farm staff is impractical in a commercial setting to the degree required to detect behavioural changes relevant for early intervention. An automated monitoring system is developed; it automatically tracks pig movement with depth video cameras, and automatically measures standing, feeding, drinking, and locomotor activities from 3D trajectories...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29239527/removal-of-epileptically-compromised-tissue-in-the-frontal-cortex-restores-oculomotor-selection-in-the-antisaccade-task
#13
Stefan Van der Stigchel, Frans S S Leijten, Mariska J Vansteensel, Hendrik Chris Dijkerman, Nick F Ramsey, Zachary V Freudenburg
The frontal cortex is heavily involved in oculomotor selection. Here, we investigated the neural correlates of eye movement selection during an antisaccade task in a young epileptic patient in whom the seizure focus included the frontal cortex and affected its function. Before resection surgery, the patient had difficulty in performing correct antisaccades towards the visual field contralateral to the seizure focus. Because the FEF is the only area in the human frontal cortex that is known to have a lateralized oculomotor function in the antisaccade task, this behavioural imbalance between the two visual fields suggests a disruption of FEF functioning by the nearby seizure focus...
December 14, 2017: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29239513/without-or-without-pheromone-habituation-possible-differences-between-insect-orders
#14
David Maxwell Suckling, Lloyd D Stringer, Alfredo Jiménez-Pérez, Gimme H Walter, Nicola Sullivan, Ashraf M El-Sayed
BACKGROUND: Habituation to sex pheromones is one of the key mechanisms in mating disruption, an insect control tactic. Male moths often show reduced sexual response after pre-exposure to female sex pheromone. Mating disruption is relatively rare in insect orders other than Lepidoptera. RESULTS: As a positive control we confirmed habituation in a moth (Epiphyas postvittana) using 24 h pre-exposure to sex pheromone to reduce subsequent activation behaviour. We then tested the impact of pre-exposure to sex or trail pheromone on subsequent behavioural response with insects from three other orders...
December 14, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29235590/unravelling-the-hydrophobicity-of-urea-in-water-using-thermodiffusion-implications-for-protein-denaturation
#15
Doreen Niether, Silvia Di Lecce, Fernando Bresme, Simone Wiegand
Urea is widely used as a protein denaturant in aqueous solutions. Experimental and computer simulation studies have shown that it dissolves in water almost ideally at high concentrations, introducing little disruption in the water hydrogen bonded structure. However, at concentrations of the order of 5 M or higher, urea induces denaturation in a wide range of proteins. The origin of this behaviour is not completely understood, but it is believed to stem from a balance between urea-protein and urea-water interactions, with urea becoming possibly hydrophobic at a specific concentration range...
December 13, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29234010/loss-of-the-molecular-clock-in-myeloid-cells-exacerbates-t-cell-mediated-cns-autoimmune-disease
#16
Caroline E Sutton, Conor M Finlay, Mathilde Raverdeau, James O Early, Joseph DeCourcey, Zbigniew Zaslona, Luke A J O'Neill, Kingston H G Mills, Annie M Curtis
The transcription factor BMAL1 is a core component of the molecular clock, regulating biological pathways that drive 24 h (circadian) rhythms in behaviour and physiology. The molecular clock has a profound influence on innate immune function, and circadian disruption is linked with increased incidence of multiple sclerosis (MS). However, the mechanisms underlying this association are unknown. Here we show that BMAL1 and time-of-day regulate the accumulation and activation of various immune cells in a CNS autoimmune disease model, experimental autoimmune encephalomyelitis (EAE)...
December 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/29225887/a-prospective-longitudinal-study-of-men-with-borderline-personality-disorder-with-and-without-comorbid-antisocial-personality-disorder
#17
Marie-Pier Robitaille, Dave Checknita, Frank Vitaro, Richard E Tremblay, Joel Paris, Sheilagh Hodgins
Background: Some evidence suggests that the prevalence of Borderline Personality Disorder (BPD) is elevated among male criminal offenders. It is not presently known whether offending, and violent offending, are limited to those presenting comorbid Antisocial Personality Disorder (ASPD) who have a childhood history of conduct problems and whether offending is linked to psychopathic traits. Methods: A community sample of 311 males followed from age 6 to 33 years, one third of whom had a criminal charge between ages 18 and 24, completed diagnostic interviews and the Psychopathy Checklist-Revised interview...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/29219089/health-impacts-of-climate-change-and-health-and-social-inequalities-in-the-uk
#18
REVIEW
Jouni Paavola
This article examines how social and health inequalities shape the health impacts of climate change in the UK, and what the implications are for climate change adaptation and health care provision. The evidence generated by the other articles of the special issue were interpreted using social justice reasoning in light of additional literature, to draw out the key implications of health and social inequalities for health outcomes of climate change. Exposure to heat and cold, air pollution, pollen, food safety risks, disruptions to access to and functioning of health services and facilities, emerging infections and flooding are examined as the key impacts of climate change influencing health outcomes...
December 5, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29216874/factors-influencing-the-experience-of-sexual-and-reproductive-healthcare-for-female-adolescents-with-perinatally-acquired-hiv-a-qualitative-case-study
#19
Gertrude Mwalabu, Catrin Evans, Sarah Redsell
BACKGROUND: Young people living with perinatally-acquired HIV require age-appropriate support regarding sex and relationships as they progress towards adulthood. HIV affects both genders but evidence suggests that young women are particularly vulnerable to sexual abuse and more prone to engaging in sexual behaviours to meet their daily survival needs. This can result in poor sexual and reproductive health (SRH) outcomes. HIV services in Malawi provide support for young women's HIV-related clinical needs, but it is unclear whether there is sufficient provision for their SRH needs as they become adults...
December 8, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29215670/is-a-strong-axial-crystal-field-the-only-essential-condition-for-a-large-magnetic-anisotropy-barrier-the-case-of-non-kramers-ho-iii-versus-tb-iii
#20
Sandeep K Gupta, Thayalan Rajeshkumar, Gopalan Rajaraman, Ramaswamy Murugavel
A monometallic non-Kramers Ho(iii) complex with a strong uniaxial ligand field displays a record high energy barrier of 355 K with hysteresis opening up to 4 K at a sweep rate of 0.027 T s-1, while the isomorphous, more anisotropic non-Kramers Tb(iii) complex displays strong quantum tunnelling between the ground states. Ab initio calculations reveal that the presence of strong axial ligands and moderately weaker equatorial ligands is sufficient to quench the QTM between the ground pseudo doublets (mJ = ±8) in the case of Ho(iii) complex, where the relaxation is found to proceed via the first excited state...
December 7, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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