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https://www.readbyqxmd.com/read/29345736/palbociclib-in-combination-with-letrozole-as-first-line-treatment-for-advanced-breast-cancer-a-japanese-phase-ii-study
#1
Norikazu Masuda, Reiki Nishimura, Masato Takahashi, Kenichi Inoue, Shinji Ohno, Hiroji Iwata, Yuko Mori, Satoshi Hashigaki, Yasuaki Muramatsu, Takashi Nagasawa, Yoshiko Umeyama, Masakazu Toi
This single-arm, open-label, phase II study in 42 Japanese postmenopausal patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative (ER+/HER2-) advanced breast cancer evaluated the efficacy, safety, and pharmacokinetics of first-line palbociclib (125 mg once daily, 3 weeks on/1 week off) coadministered with letrozole (2.5 mg once daily). The primary endpoint of investigator-assessed 1-year progression-free survival probability was 75.0% (90% CI, 61.3%-84.4%), far surpassing the 40% lower limit of the 90% CI supporting efficacy...
January 18, 2018: Cancer Science
https://www.readbyqxmd.com/read/29315084/safety-of-reiki-therapy-for-newborns-at-risk-for-neonatal-abstinence-syndrome
#2
Rosanne Marie Radziewicz, Sandra Wright-Esber, Julie Zupancic, Deb Gargiulo, Patricia Woodall
The incidence of opioid abuse and subsequent drug withdrawal is exponentially on the rise in the United States for many populations including newborns who are born to drug-addicted mothers. These newborns often exhibit symptoms of neonatal abstinence syndrome (NAS) within 24 to 72 hours of birth. Treatment of NAS includes monitoring of withdrawal symptoms, managing physiological parameters, and the use of supportive and pharmacologic treatments. Although a few randomized controlled trials exist, studies on supportive intervention are generally limited by small sample sizes, case study reports, expert opinions, and descriptive design...
January 8, 2018: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29228783/training-in-integrative-therapies-increases-self-efficacy-in-providing-nondrug-therapies-and-self-confidence-in-offering-compassionate-care
#3
Kathi J Kemper, Ellie Hill
BACKGROUND: Patient demand and clinician interest have driven professional training in integrative therapies, but few rigorous evaluations have been published. METHODS: This project evaluated the proof of concept of training in acupressure, guided imagery, massage, and Reiki on clinicians' sense of self-efficacy in providing nondrug therapies, self-confidence in providing compassionate care, and engagement with work. RESULTS: Three out of 4 topics met minimum enrollment numbers; 22 of 24 participants completed follow-up as well as pretraining surveys...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29066578/r-spondin1-expands-paneth-cells-and-prevents-dysbiosis-induced-by-graft-versus-host-disease
#4
Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, Clara Noizat, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Yuki Yokoi, Rina Sugimoto, Satomi Matsuoka, Takahide Ara, Emi Yokoyama, Tomohiro Yamakawa, Ko Ebata, Takeshi Kondo, Rina Hiramine, Tomoyasu Aizawa, Yoshitoshi Ogura, Tetsuya Hayashi, Hiroshi Mori, Ken Kurokawa, Kazuma Tomizuka, Tokiyoshi Ayabe, Takanori Teshima
The intestinal microbial ecosystem is actively regulated by Paneth cell-derived antimicrobial peptides such as α-defensins. Various disorders, including graft-versus-host disease (GVHD), disrupt Paneth cell functions, resulting in unfavorably altered intestinal microbiota (dysbiosis), which further accelerates the underlying diseases. Current strategies to restore the gut ecosystem are bacteriotherapy such as fecal microbiota transplantation and probiotics, and no physiological approach has been developed so far...
October 24, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28968143/mental-health-wellness-and-biofield-therapies-an-integrative-review
#5
Lucrezia Mangione, Diane Swengros, Joel G Anderson
Biofield therapies such as Healing Touch and Reiki increase relaxation, decrease anxiety and stress, and improve mood. Understanding the efficacy of these therapies in terms of mental health wellness is important for nurses interested in complementary and integrative care. The goal of the present integrative review was to investigate the state of knowledge regarding biofield therapies and the impact on anxiety, mood, and mental health wellness. Electronic databases were searched for articles available in English and published from 2014 to 2016...
November 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28874060/reiki-is-better-than-placebo-and-has-broad-potential-as-a-complementary-health-therapy
#6
David E McManus
This study reviews the available clinical studies of Reiki to determine whether there is evidence for Reiki providing more than just a placebo effect. The available English-language literature of Reiki was reviewed, specifically for peer-reviewed clinical studies with more than 20 participants in the Reiki treatment arm, controlling for a placebo effect. Of the 13 suitable studies, 8 demonstrated Reiki being more effective than placebo, 4 found no difference but had questionable statistical resolving power, and only one provided clear evidence for not providing benefit...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28845677/massage-therapy-in-outpatient-cancer-care-a-metropolitan-area-analysis
#7
Virginia S Cowen, Robin Streit Miccio, Bijal Parikh
Massage offers cancer patients general quality of life benefits as well as alleviation of cancer-related symptoms/cancer-treatment-related symptoms including pain, anxiety, and fatigue. Little is known about whether massage is accessible to cancer patients who receive treatment in the outpatient setting and how massage is incorporated into the overall cancer treatment plan. Outpatient cancer centers (n = 78) in a single metropolitan area were included this mixed-methods project that included a systematic analysis of website information and a telephone survey...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28794663/physician-perspectives-on-education-training-and-implementation-of-complementary-and-alternative-medicine
#8
Sejal J Patel, Kathi J Kemper, Joseph P Kitzmiller
Over recent decades, the demand for complementary and alternative medicine (CAM) has continued to rise in the US. Like the practice of traditional Western medicine, CAM is associated with not only significant health benefits but also significant risks. Unlike traditional Western medicine, however, much of CAM use is less regulated and often occurs unbeknownst to a patient's medical doctor. The use of herbals, dietary supplements, and over-the-counter (OTC) medications can result in adverse effects, and many significant interactions can occur when their use is combined with allopathic medications...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28735986/challenges-for-the-travelling-donor-variability-between-donor-workup-and-donor-surgery-in-the-canadian-kidney-paired-exchange-program
#9
B A Reikie, T Kroczak, T B McGregor
BACKGROUND: A primary obstacle to providing renal transplantation is limited access to donated kidneys. The living-donor pool for renal allografts was greatly expanded through implementation of a kidney paired donation program. Whereas some programs ship donor kidneys to the site of renal transplantation, others send the donor to the site of transplantation. Performing the nephrectomy and transplantation at the same location may optimize functional renal outcomes, but preferred surgical approaches may differ between surgical teams performing the donor workup and donor surgery...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28668857/self-efficacy-for-coping-with-cancer-enhances-the-effect-of-reiki-treatments-during-the-pre-surgery-phase-of-breast-cancer-patients
#10
RANDOMIZED CONTROLLED TRIAL
Andrea Chirico, Giuseppe D'Aiuto, Antonella Penon, Luca Mallia, Michelino DE Laurentiis, Fabio Lucidi, Gerardo Botti, Antonio Giordano
BACKGROUND/AIM: Self-efficacy for coping with cancer plays a critical role in influencing psychological cancer-related outcomes, some studies suggested its role in enhancing or reducing the effects of psychological interventions in cancer patients. Reiki has recently been included among the efficacious complementary therapeutic intervention for cancer patients. PATIENTS AND METHODS: The present study evaluated the role of self-efficacy for coping with cancer as buffer of the Reiki treatment effects on cancer-related symptoms in a randomized controlled trial (intervention versus control group) of breast cancer patients (N=110) during the pre-surgery phase...
July 2017: Anticancer Research
https://www.readbyqxmd.com/read/28654301/an-integrative-review-of-scientific-evidence-for-reconnective-healing
#11
REVIEW
Ann L Baldwin, Natalie L Trent
BACKGROUND: Biofield therapies offer a novel, non-invasive approach to treating chronic diseases based on assessing and adjusting an individual's physiological and emotional responses through their bio-energetic field. Reconnective Healing(™) (RH) is defined as: "…not just energy healing, but instead a more comprehensive spectrum of healing composed of energy, light, and information." OBJECTIVES: Several biofield therapies, such as Reiki, Therapeutic Touch and Johrei, have already been reviewed in the literature but RH has received little attention even though it is taught and practiced worldwide...
August 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28572102/complementary-health-practitioners-in-the-acute-and-critical-care-setting-nursing-considerations
#12
Debra Kramlich
In response to the rising demand by patients and their families for complementary health approaches, hospitals are increasingly integrating complementary health approaches with their conventional medical practices to create healing environments. Results of the 2010 Complementary and Alternative Medicine Survey of Hospitals indicated that the top 6 inpatient modalities included pet therapy, massage therapy, music or art therapy, guided imagery, relaxation therapy, and Reiki and therapeutic touch. Whether complementary health approaches are provided by complementary health practitioners through hospital-based integrative medicine programs, volunteer practitioners, or bedside nurses, the regulatory, legal, ethical, and safety concerns remain constant...
June 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/28497700/instrumental-measurements-of-water-and-the-surrounding-space-during-a-randomized-blinded-controlled-trial-of-focused-intention
#13
Luís Carlos Matos, Sara Cristina Santos, Joel G Anderson, Jorge Machado, Henry Johannes Greten, Fernando Jorge Monteiro
The main goal of this work was the assessment of measurable interactions induced by focused intention, frequently used in biofield practices such as Healing Touch and Reiki. Water, as the main component of the human body, was chosen as a model. Intention experiments were performed over 4 different days at a scheduled interval, during which 286 trained biofield practitioners from several countries were instructed to meditate with the intention to change the molecular vibrational state of water samples selected by a blinded operator...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28443949/is-reiki-or-prayer-effective-in-relieving-pain-during-hospitalization-for-cesarean-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
Guilherme Augusto Rago Ferraz, Meline Rosseto Kron Rodrigues, Silvana Andrea Molina Lima, Marcelo Aparecido Ferraz Lima, Gabriela Lopes Maia, Carlos Alberto Pilan, Michelle Sako Omodei, Ana Cláudia Molina, Regina El Dib, Marilza Vieira Cunha Rudge
CONTEXT AND OBJECTIVE: This systematic review compared reiki and prayer with drug use for relieving pain during hospitalization for cesarean, given that the popularity of integrative medicine and spiritual healing has been increasing. It had the aim of evaluating whether reiki or prayer is effective in relieving pain during cesarean section. DESIGN AND SETTING: Systematic review with meta-analysis conducted at Botucatu Medical School, UNESP, São Paulo, Brazil. METHODS: The following databases were searched up to March 2016: MEDLINE, Embase, LILACS and CENTRAL...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28181973/effects-of-reiki-on-pain-anxiety-and-blood-pressure-in-patients-undergoing-knee-replacement-a-pilot-study
#15
RANDOMIZED CONTROLLED TRIAL
Ann Linda Baldwin, Anne Vitale, Elise Brownell, Elizabeth Kryak, William Rand
This blinded, controlled pilot study investigated the effects of Reiki on 46 patients undergoing knee replacement surgery. Of the 3 groups, Reiki, Sham Reiki, and Standard of Care, only the Reiki group showed significant reductions in pain, blood pressure, respiration rate, and state anxiety, which provides evidence for a full-scale clinical study.
March 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/28112554/inpatients-preferences-beliefs-and-stated-willingness-to-pay-for-complementary-and-alternative-medicine-treatments
#16
Lori P Montross-Thomas, Emily A Meier, Kimberly Reynolds-Norolahi, Erin E Raskin, Daniel Slater, Paul J Mills, Lauray MacElhern, Gene Kallenberg
OBJECTIVES: Research demonstrates the benefits of complementary and alternative medicine (CAM) in myriad environments. Yet, the majority of CAM services are offered in outpatient settings. Incorporating CAM into hospital settings may lead to increased patient comfort, well-being, and overall satisfaction with hospital admissions. Few studies have examined CAM services among inpatients. Therefore, this study assessed inpatients' preferences and beliefs regarding CAM, as well as their stated willingness to pay for these services...
April 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28111393/basic-study-for-the-purpose-of-developing-a-quantitative-67-ga-spect-measurement-method
#17
Kensuke Nakanishi, Reiki Sakata, Akihiro Takaki, Yutaka Nakasone, Masataka Kadota, Shigeki Ito
PURPOSE: (67)Ga-single photon emission computed tomography (SPECT) images vary according to the imaging time and image display methods. The calculation of an index, such as the standardized uptake value used in positron emission tomography, from (67)Ga-SPECT images would enable the accurate evaluation of the region of accumulation. The purpose of this study was to elucidate the conversion formula, the lower detection limit (LDL), and recovery coefficient (RC) for quantifying the radiation concentration in the (67)Ga accumulation site...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28107186/the-combination-of-pd-l1-expression-and-decreased-tumor-infiltrating-lymphocytes-is-associated-with-a-poor-prognosis-in-triple-negative-breast-cancer
#18
Hitomi Mori, Makoto Kubo, Rin Yamaguchi, Reiki Nishimura, Tomofumi Osako, Nobuyuki Arima, Yasuhiro Okumura, Masayuki Okido, Mai Yamada, Masaya Kai, Junji Kishimoto, Yoshinao Oda, Masafumi Nakamura
This study included patients with primary triple-negative breast cancer (TNBC) who underwent resection without neoadjuvant chemotherapy between January 2004 and December 2014. Among the 248 TNBCs studied, programmed cell death ligand-1 (PD-L1) expression was detected in 103 (41.5%) tumors, and high levels of tumor-infiltrating lymphocytes (TILs) were present in 118 (47.6%) tumors. PD-L1 expression correlated with high levels of TILs, but was not a prognostic factor. Patients with TILs-high tumors had better overall survival than those with TILs-low tumors (P = 0...
February 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28056400/efficacy-and-safety-of-eribulin-as-first-to-third-line-treatment-in-patients-with-advanced-or-metastatic-breast-cancer-previously-treated-with-anthracyclines-and-taxanes
#19
Shigeto Maeda, Michiyo Saimura, Shigeki Minami, Kaname Kurashita, Reiki Nishimura, Yuichiro Kai, Hiroshi Yano, Kohjiro Mashino, Shoshu Mitsuyama, Mototsugu Shimokawa, Kazuo Tamura
OBJECTIVES: Despite the survival benefit and acceptable tolerability of eribulin for advanced/metastatic breast cancer (MBC) patients pretreated with anthracyclines and taxanes, there is limited evidence of the clinical benefit of early eribulin use. We investigated the efficacy and safety of first- to third-line eribulin use in patients with MBC. MATERIALS AND METHODS: In this phase II, open-label, single-arm study conducted at 14 sites in Kyushu, Japan, women with histologically confirmed human epidermal growth factor receptor 2-negative MBC were enrolled between December 1, 2011 and November 30, 2013 (Data cut-off: November 30, 2014)...
April 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27903524/graft-versus-host-disease-targets-ovary-and-causes-female-infertility-in-mice
#20
Sonoko Shimoji, Daigo Hashimoto, Hidetsugu Tsujigiwa, Kohta Miyawaki, Koji Kato, Shuichiro Takahashi, Reiki Ogasawara, Takashi Jiromaru, Hiromi Iwasaki, Toshihiro Miyamoto, Koichi Akashi, Takanori Teshima
Infertility associated with ovarian failure is a serious late complication for female survivors of allogeneic hematopoietic stem cell transplantation (SCT). Although pretransplant conditioning regimen has been appreciated as a cause of ovarian failure, increased application of reduced-intensity conditioning allowed us to revisit other factors possibly affecting ovarian function after allogeneic SCT. We have addressed whether donor T-cell-mediated graft-versus-host disease (GVHD) could be causally related to female infertility in mice...
March 2, 2017: Blood
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