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https://www.readbyqxmd.com/read/28732244/thyroglossal-duct-cysts-in-children-sonographic-features-every-radiologist-should-know-and-their-histopathological-correlation
#1
REVIEW
Emilio Inarejos Clemente, Modupe Oyewumi, Evan Probst, Bo-Yee Ngan, Mary-Louise Greer
Distinguishing between thyroglossal duct cysts (TGDC) and dermoid cysts (DC) sonographically can be challenging. We illustrate the three sonographic features in neck masses in children recently identified as being most suggestive of TGDC (septa, irregular wall and solid elements) and their corresponding histopathology. These three variables form a proposed predictive model for TGDC as a guide to surgical intervention. Pediatric radiologists should be familiar with these key imaging features, as compared with other imaging features described in TGDC also illustrated here, which are less discriminating...
July 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28728931/new-anthracenyl-polar-embedded-stationary-phases-with-enhanced-aromatic-selectivity-a-combined-experimental-and-theoretical-study-part-1-experimental-study
#2
Mélanie Mignot, Clément De Saint Jores, Alain Tchapla, François Boyer, Pascal Cardinael, Valérie Peulon-Agasse
New polar embedded aromatic stationary phases of different functionalities (mono- and trifunctional) and on different silica supports (Fully Porous Particle (FPP) and Superficially Porous Particle (SPP)) were synthesized to determine the impact of the functionality on the retention process and the selectivity towards aromatic compounds. A full experimental characterization was performed using a combination of techniques (elemental analysis, thermogravimetric measurements, infrared spectroscopy and solid-state NMR) to differentiate unambiguously the mono- and trifunctional Stationary Phases (SP)...
June 27, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28727662/paraphilic-thoughts-behaviors-and-sex-addiction-in-a-sample-of-persons-who-use-drugs-a-cross-sectional-study
#3
Jales Clemente, Sandra Cristina Pillon, Jair de Jesus Mari, Claudio Jeronimo da Silva, Paulo Roberto Henrique Santana, Alessandra Diehl
OBJECTIVE: The aim of this study was to evaluate the prevalence of paraphilic thoughts/behaviors (including paraphilic disorders) with and without sexual addiction and sexual-related conditions in a sample of substance disorder patients. METHODS: This was a cross-sectional study of substance-dependent individuals who sought outpatient treatment in São Paulo, Brazil. Data included sociodemographic information, drug of choice, responses to questions about sexual behavior, and to the following standardized questionnaires: (a) Sexual Addiction Screening Test, and (b) Childhood Trauma Questionnaire...
July 19, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28726634/birth-and-death-of-a-protein
#4
Julie Clément, Bernard de Massy
The ways in which recombination sites are determined during meiosis are becoming clearer following a phylogenomic analysis for 225 different species.
July 20, 2017: ELife
https://www.readbyqxmd.com/read/28724627/using-step-width-to-compare-locomotor-biomechanics-between-extinct-non-avian-theropod-dinosaurs-and-modern-obligate-bipeds
#5
P J Bishop, C J Clemente, R E Weems, D F Graham, L P Lamas, J R Hutchinson, J Rubenson, R S Wilson, S A Hocknull, R S Barrett, D G Lloyd
How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study, step width-the mediolateral (transverse) distance between successive footfalls-was investigated with respect to speed (stride length) in non-avian theropod trackways of Late Triassic age. Comparable kinematic data were also collected for humans and 11 species of ground-dwelling birds...
July 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28724024/stigma-related-to-bipolar-disorder-in-the-perception-of-psychiatrists-from-belo-horizonte-minas-gerais-state-brazil
#6
Adauto Silva Clemente, Wagner Jorge Dos Santos, Rodrigo Nicolato, Josélia Oliveira Araújo Firmo
This research sought to understand meanings and implications of the stigma related to bipolar disorder in relation to social processes and local cultural value systems. Seven semidirected individual interviews were performed with psychiatrists (from Belo Horizonte city, Minas Gerais State, Brazil) and analyzed with referential from the Medical Anthropology. Some potential stigmatizing views about bipolar disorder patients were endorsed by respondents related to biomedical model of bipolar disorder. They claimed about the extreme trivialization of this diagnosis nowadays and observed that, in spite of the mitigation of stigma related to bipolar disorder over time, it remains an important issue, especially at labor fields and as a cause of refusal of treatment...
July 13, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28723931/why-aren-t-people-with-young-onset-dementia-and-their-supporters-using-formal-services-results-from-the-inspired-study
#7
Monica Cations, Adrienne Withall, Ruth Horsfall, Nicole Denham, Fiona White, Julian Trollor, Clement Loy, Henry Brodaty, Perminder Sachdev, Peter Gonski, Apo Demirkol, Robert G Cumming, Brian Draper
BACKGROUND/AIMS: Despite reporting high levels of burden, supporters of people with young onset dementia (YOD) underuse formal community services. Previous quantitative studies in YOD are of limited utility in guiding service design because they did not consider important contextual barriers to service use. The aim of this study was to identify all relevant barriers and describe the service features considered most important to improving uptake by people with YOD and their supporters...
2017: PloS One
https://www.readbyqxmd.com/read/28722802/pathology-imagebase-a-reference-image-database-for-standardization-of-pathology
#8
Lars Egevad, John Cheville, Andrew J Evans, Jonas Hörnblad, James G Kench, Glen Kristiansen, Katia R M Leite, Cristina Magi-Galluzzi, Chin-Chen Pan, Hemamali Samaratunga, John R Srigley, Lawrence True, Ming Zhou, Mark Clements, Brett Delahunt
AIMS: Despite efforts to standardize histopathology practice through the development of guidelines, the interpretation of morphology is still hampered by subjectivity. We here describe Pathology Imagebase, a novel mechanism for establishing an international standard for the interpretation of pathology specimens. METHODS AND RESULTS: The International Society of Urological Pathology (ISUP) established a reference image database through the input of experts in the field...
July 19, 2017: Histopathology
https://www.readbyqxmd.com/read/28722631/dengue-virus-coinfection-in-human-immunodeficiency-virus-1-infected-patients-on-the-west-coast-of-mexico
#9
Francisco Espinoza-Gómez, Iván Delgado-Enciso, Salvador Valle-Reyes, Rodolfo Ochoa-Jiménez, Conrado Arechiga-Ramírez, José L Gámez-Arroyo, Roberto Vázquez-Campuzano, Carmen Guzmán-Bracho, Clemente Vásquez, Uriel A López-Lemus
Dengue virus infection in human immunodeficiency virus (HIV)-positive patients is not well studied. Previous reports suggest a transitory inhibition of the HIV-1 viral load, as well as a benign clinical progression of dengue. The follow-up of six HIV-1-infected patients, diagnosed and hospitalized with dengue virus infection in the State of Colima, Mexico, was carried out to analyze the progression of this viral coinfection. The presence of dengue virus serotype 1 was confirmed through molecular tests. No severe complications were observed in any of the patients during dengue virus infection...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28721339/the-role-of-glucagon-like-peptide-1-receptor-agonists-in-the-treatment-of-type-2-diabetes
#10
Erin St Onge, Shannon Miller, Elizabeth Clements, Lindsay Celauro, Ke'la Barnes
The role of GLP-1 agonists in the treatment of type 2 diabetes have been shown to be viable options for add-on therapy in diabetic patients, as well as potential monotherapy options. With six available GLP-1 agents, and new combination products in the pipeline, they are a promising drug class for type 2 diabetic patients, especially due to their extended dosing interval and potential weight loss benefits.
June 2017: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/28719555/the-influence-of-shortening-on-clinical-outcome-in-healed-displaced-midshaft-clavicular-fractures-after-nonoperative-treatment
#11
E B Goudie, N D Clement, I R Murray, C R Lawrence, M Wilson, A J Brooksbank, C M Robinson
BACKGROUND: We aimed to evaluate the effect of clavicular shortening, measured with 3-dimensional computed tomography (3DCT), on functional outcomes and satisfaction in patients with healed displaced midshaft clavicular fractures up to 1 year following injury. METHODS: The data used in this study were collected as part of a multicenter, prospective randomized controlled trial of open reduction and plate fixation compared with nonoperative treatment for acute, displaced midshaft clavicular factures...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28719431/bispectral-index-measurements-are-not-degraded-during-aeromedical-evacuations
#12
Nicolas Donat, Audrey Cirodde, Clément Hoffmann, Jean-Vivien Schaal, Yannick Masson, Antoine Nau, Paul Vincent Martin, Samuel Madec, Thomas Leclerc
For a decade, depth of anesthesia monitoring has become a reality in the operating room. It provides valuable help for managing anesthesia, especially for unstable patients. This might be particularly relevant during aeromedical evacuation. In this study, we aimed to assess the validity of the bispectral index (BIS) during long-range patient transportation aboard fixed-wing aircraft. BIS was recorded in 30 patients, 25 under anesthesia and 5 awake, during aeromedical evacuations performed by the French Air Force...
July 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28719317/climate-influence-on-emerging-risk-areas-for-rift-valley-fever-epidemics-in-tanzania
#13
Clement N Mweya, Leonard E G Mboera, Sharadhuli I Kimera
Rift Valley Fever (RVF) is a climate-related arboviral infection of animals and humans. Climate is thought to represent a threat toward emerging risk areas for RVF epidemics globally. The objective of this study was to evaluate influence of climate on distribution of suitable breeding habitats for Culex pipiens complex, potential mosquito vector responsible for transmission and distribution of disease epidemics risk areas in Tanzania. We used ecological niche models to estimate potential distribution of disease risk areas based on vectors and disease co-occurrence data approach...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717304/letter-to-the-editor-can-vagus-nerve-schwannoma-masquerade-as-a-carotid-chemodectoma
#14
Joseph Benzakoun, Clement Cholet, Nadya Pyatigorskaya, Stephanie Trunet, Didier Dormont, Delphine Leclercq, Bruno Law-Ye
No abstract text is available yet for this article.
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28717027/regulation-of-the-calvin-benson-bassham-cycle-in-the-enigmatic-diatoms-biochemical-and-evolutionary-variations-on-an-original-theme
#15
REVIEW
Erik Jensen, Romain Clément, Stephen C Maberly, Brigitte Gontero
In Plantae, the Calvin-Benson-Bassham (CBB) cycle is highly regulated and most of its enzymes have been thoroughly studied. Since diatoms arose as a result of secondary endosymbiosis with one or more Plantae ancestors, their precise evolutionary history is enigmatic and complex resulting in biochemical variations on the original CBB cycle theme. The Rubisco Michaelis constant for CO2 is higher in diatoms than land plants and the nuclear-encoded Rubisco activase in Plantae is replaced by an analogous chloroplast-encoded CbbX (Calvin-Benson-Bassham protein X) in diatoms...
September 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28716983/systematic-review-of-the-cost-and-cost-effectiveness-of-rapid-endovascular-therapy-for-acute-ischemic-stroke
#16
Laura K Sevick, Sarah Ghali, Michael D Hill, Vishva Danthurebandara, Diane L Lorenzetti, Tom Noseworthy, Eldon Spackman, Fiona Clement
BACKGROUND AND PURPOSE: Rapid endovascular therapy (EVT) is an emerging treatment option for acute ischemic stroke. Several economic evaluations have been published examining the cost-effectiveness of EVT, and many international bodies are currently making adoption decisions. The objective of this study was to establish the cost-effectiveness of EVT for ischemic stroke patients and to synthesize all the publicly available economic literature. METHODS: A systematic review of the published literature was conducted to identify economic evaluations and cost analyses of EVT for acute ischemic stroke patients...
July 17, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28715460/early-infant-diagnosis-of-hiv-1-infection-in-luanda-angola-using-a-new-dna-pcr-assay-and-dried-blood-spots
#17
Francisco Martin, Claudia Palladino, Rita Mateus, Anna Bolzan, Perpétua Gomes, José Brito, Ana Patrícia Carvalho, Yolanda Cardoso, Cristovão Domingos, Vanda Sofia Lôa Clemente, Nuno Taveira
BACKGROUND: Early diagnosis and treatment reduces HIV-1-related mortality, morbidity and size of viral reservoirs in infants infected perinatally. Commercial molecular tests enable the early diagnosis of infection in infants but the high cost and low sensitivity with dried blood spots (DBS) limit their use in sub-Saharan Africa. OBJECTIVES: To develop and validate a sensitive and cheap qualitative proviral DNA PCR-based assay for early infant diagnosis (EID) in HIV-1-exposed infants using DBS samples...
2017: PloS One
https://www.readbyqxmd.com/read/28715449/a-unique-enhancer-boundary-complex-on-the-mouse-ribosomal-rna-genes-persists-after-loss-of-rrn3-or-ubf-and-the-inactivation-of-rna-polymerase-i-transcription
#18
Chelsea Herdman, Jean-Clement Mars, Victor Y Stefanovsky, Michel G Tremblay, Marianne Sabourin-Felix, Helen Lindsay, Mark D Robinson, Tom Moss
Transcription of the several hundred of mouse and human Ribosomal RNA (rRNA) genes accounts for the majority of RNA synthesis in the cell nucleus and is the determinant of cytoplasmic ribosome abundance, a key factor in regulating gene expression. The rRNA genes, referred to globally as the rDNA, are clustered as direct repeats at the Nucleolar Organiser Regions, NORs, of several chromosomes, and in many cells the active repeats are transcribed at near saturation levels. The rDNA is also a hotspot of recombination and chromosome breakage, and hence understanding its control has broad importance...
July 17, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28714894/carbonic-anhydrase-from-porphyromonas-gingivalis-as-a-drug-target
#19
REVIEW
Claudiu T Supuran, Clemente Capasso
Periodontitis originates from a microbial synergy causing the development of a mouth microbial imbalance (dysbiosis), consisting of a microbial community composed of anaerobic bacteria. Most studies concerning the treatment of periodontitis have primarily take into account the Gram-negative bacterium Porphyromonas gingivalis, because it is a prominent component of the oral microbiome and a successful colonizer of the oral epithelium. Here, we focus our attention on the study of the carbonic anhydrases (CAs, EC 4...
July 15, 2017: Pathogens
https://www.readbyqxmd.com/read/28714574/a-humanised-tissue-engineered-bone-model-allows-species-specific-breast-cancer-related-bone-metastasis-in-vivo
#20
V M C Quent, A V Taubenberger, J C Reichert, L C Martine, J A Clements, D W Hutmacher, D Loessner
Bone metastases frequently occur in the advanced stages of breast cancer. At this stage, the disease is deemed incurable. To date, the mechanisms of breast cancer-related metastasis to bone are poorly understood. This may be attributed to the lack of appropriate animal models to investigate the complex cancer cell-bone interactions. In this study, two established tissue-engineered bone constructs (TEBCs) were applied to a breast cancer-related metastasis model. A cylindrical medical-grade polycaprolactone-tricalcium phosphate scaffold produced by fused deposition modelling (scaffold 1) was compared with a tubular calcium phosphate-coated polycaprolactone scaffold fabricated by solution electrospinning (scaffold 2) for their potential to generate ectopic humanised bone in NOD/SCID mice...
July 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
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