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https://www.readbyqxmd.com/read/29678273/preoperative-ct-based-predictive-factors-for-resectability-and-medium-term-overall-survival-in-patients-with-peritoneal-carcinomatosis-from-colorectal-cancer
#1
C Suzuki, H Wallgren, M Abraham-Nordling, G Palmer
AIM: To determine preoperative radiological findings that may correlate with resectability and medium-term overall survival (OS) in patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC). MATERIALS AND METHODS: The study included 81 consecutive patients with PC scheduled for cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). PCI scores from preoperative computed tomography (CT) were compared with Peritoneal Cancer Index (PCI) scores at laparotomy...
April 17, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29670226/analysis-for-patient-survival-after-open-abdomen-for-torso-trauma-and-the-impact-of-achieving-primary-fascial-closure-a-single-center-experience
#2
Yu-Pao Hsu, Yon-Cheong Wong, Chih-Yuan Fu, Shang-Yu Wang, Chien-Hung Liao, Chun-Hsiang Ou Yang, Kuo-Ching Yuan
Open abdomen indicates the abdominal fascia is unclosed to abbreviate surgery and to reduce physiological stress. However, complications and difficulties in patient care are often encountered after operation. During May 2008 to March 2013, we performed a prospective protocol-directed observation study regarding open abdomen use in trauma patients. Bogota bag is the temporary abdomen closure initially but negative pressure dressing is used later. A goal-directed ICU care is applied and primary fascial closure is the primary endpoint...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29661290/factors-affecting-the-caloric-and-protein-intake-over-time-in-critically-ill-trauma-patients
#3
Tobias Haltmeier, Kenji Inaba, Beat Schnüriger, Stefano Siboni, Elizabeth Benjamin, Lydia Lam, Damon Clark, Demetrios Demetriades
BACKGROUND: Major trauma leads to increased nutritional requirements. However, little is known about the actual amount of calories and protein administered and the factors affecting the intake over time in critically ill trauma patients. METHODS: Prospective study including 100 trauma patients admitted to the Los Angeles County + University of Southern California Medical Center intensive care unit between March 2014 and October 2014. Inclusion criteria were age > 16 y, surgery at admission, and no oral nutrition...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29621060/prediction-of-the-development-of-persistent-massive-ascites-after-living-donor-liver-transplantation-using-a-perioperative-risk-score
#4
Yi-Ju Wu, Shih-Ho Wang, Ahmed M Elsarawy, Yi-Chia Chan, Chao-Long Chen, Ben-Chung Cheng, Lung-Chi Li, Chien-Hua Chiu, Yi-Wei Lee, Yu-Cheng Lin, Sin-Yong Wee, Cheng-Chung Pan, Yu-Yin Kao, Ying-Hsiu Chen, Hsiao-Wen Lin, Li-Man Lin, Chih-Che Lin
BACKGROUND: Persistent massive ascites (PMAS) >14 days after living donor liver transplantation (LDLT) is not uncommon and associated with worse outcome. A predictive risk scoring system was constructed after analysis of recipient, graft and surgery related factors. METHODS: We retrospectively reviewed adult LDLT recipients from 2005 to 2011 after excluding cases that experienced any intervention for perioperative vascular-related events. Two groups were identified; PMAS and non-PMAS...
April 5, 2018: Transplantation
https://www.readbyqxmd.com/read/29616320/trauma-patients-with-an-open-abdomen-following-damage-control-laparotomy-can-be-extubated-prior-to-abdominal-closure
#5
Joseph A Sujka, Karen Safcsak, Michael L Cheatham, Joseph A Ibrahim
BACKGROUND: The open abdomen (OA) is commonly utilized as a technique during damage control laparotomy (DCL). We propose that a selected group of these OA patients can be extubated prior to abdominal closure to decrease ventilator days and risk of pneumonia. METHODS: A retrospective chart review was performed at a Level I trauma center on all adult trauma patients with an OA following DCL. Patients were stratified into two groups: extubated prior to (PRE) and extubated after (POST) abdominal closure...
April 3, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29613955/influence-of-postoperative-hepatic-angiography-on-mortality-after-laparotomy-in-grade-iv-v-hepatic-injuries
#6
Shokei Matsumoto, Emily Cantrell, Kyoungwon Jung, Alan Smith, Raul Coimbra
BACKGROUND: Mortality rate for severe liver injuries remains high. As an adjunct to surgery, postoperative hepatic angiography (PHA) may have a positive impact on outcomes. This study sought to compare outcomes following surgical management of severe liver injuries with and without PHA using propensity score matching analysis. METHODS: Data from the National Trauma Data Bank from 2007 - 2014 was analyzed. The study population consisted of patients greater than 18 years of age sustaining severe liver injuries (ie AAST-OIS grade IV or V) who underwent surgery...
April 2, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29603126/thirty-day-mortality-in-patients-undergoing-laparotomy-for-small-bowel-obstruction
#7
O Peacock, M G Bassett, A Kuryba, K Walker, E Davies, I Anderson, R S Vohra
BACKGROUND: Small bowel obstruction (SBO) is a common indication for emergency laparotomy. There are currently variations in the timing of surgery for patients with SBO and limited evidence on whether delayed surgery affects outcomes. The aim of this study was to evaluate the impact of time to operation on 30-day mortality in patients requiring emergency laparotomy for SBO. METHODS: Data were collected from the National Emergency Laparotomy Audit (NELA) on all patients aged 18 years or older who underwent emergency laparotomy for all forms of SBO between December 2013 and November 2015...
March 30, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29589984/the-effect-of-calcium-dobesilate-on-liver-damage-in-experimental-obstructive-jaundice
#8
Yilmaz Unal, Salih Tuncal, Koray Kosmaz, Berkay Kucuk, Kemal Kismet, Turgut Cavusoglu, Pinar Celepli, Mehmet Senes, Selin Yildiz, Sema Hucumenoglu
Purpose/Aim of the study: Inflammation and oxidative stress are two significant factors affecting the degree of liver damage in obstructive jaundice. The aim of this study was to evaluate the effect of calcium dobesilate (CaDob), an effective antioxidant and anti-inflammatory drug, on damage to liver caused by experimental obstructive jaundice. MATERIALS AND METHODS: 30 rats in total were randomly placed into three groups, each group consisting of 10 rats. The sham group (Group 1) only received solely laparotomy...
March 28, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29589458/laparoscopic-treatment-of-bowel-perforation-after-blunt-abdominal-trauma-bat-in-children
#9
P Zahradnikova, J Babala, Ľ Sýkora, J Trnka, M Vidiscak, P Sinka, L Fedorová
Minimally invasive techniques have now become standard for the treatment of many surgical conditions in children. There are a few studies that describe the utility of laparoscopy in BAT in children. In this article, we describe the complete laparoscopic surgical treatment of two patients after a single blunt abdominal trauma, both with bowel perforation. In both cases, the perforation was identified and closed, one laparoscopically with an ongoing suture, the second jejune perforation was closed by laparoscopic-assisted techniques...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29577217/-impact-of-previous-abdominal-surgery-on-the-outcomes-of-laparoscopic-resection-for-colorectal-cancer
#10
Jinhua Tao, Xishan Wang, Zheng Liu, Zheng Jiang, Chunguang Guo, Jianan Chen, Zhijie Wang, Qian Liu
OBJECTIVE: To investigate the effect of previous abdominal surgery(PAS) on laparoscopic resection of colorectal cancer. METHODS: The retrospective cohort study was adopted.Clinical data of consecutive colorectal cancer patients with PAS history (past history of at least one abdominal surgery, exclusion of previous inguinal hernia repair, simple laparoscopic approach, appendectomy of the right lower quadrant and endoscopic therapy) undergoing laparoscopic surgery at the Cancer Hospital of Chinese Academy of Medical Sciences between 2010 and 2015 were collected, meanwhile other colorectal cancer patients without PAS history were selected according to 1 to 1 match in age, sex, body mass index, American Society of Anesthesiologists score, tumor location, type of surgery, and staging of tumor...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29554039/direct-to-operating-room-trauma-resuscitation-decreases-mortality-among-severely-injured-children
#11
Minna M Wieck, Aaron J Cunningham, Brandon Behrens, Erika T Ohm, Bryan G Maxwell, Nicholas A Hamilton, M Christopher Adams, Frederick J Cole, Mubeen A Jafri
BACKGROUND: Expediting evaluation and intervention for severely injured patients has remained a mainstay of advanced trauma care. One technique, direct to operating room (DOR) resuscitation, for selective adult patients has demonstrated decreased mortality. We sought to investigate the application of this protocol in children. METHODS: All DOR pediatric patients from 2009-2016 at a pediatric Level I Trauma Center were identified. DOR criteria included penetrating injury, chest injuries, amputations, significant blood loss, cardiopulmonary resuscitation, and surgeon discretion...
March 16, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29546805/a-deep-neural-network-to-assess-spontaneous-pain-from-mouse-facial-expressions
#12
Alexander H Tuttle, Mark J Molinaro, Jasmine F Jethwa, Susana G Sotocinal, Juan C Prieto, Martin A Styner, Jeffrey S Mogil, Mark J Zylka
Grimace scales quantify characteristic facial expressions associated with spontaneous pain in rodents and other mammals. However, these scales have not been widely adopted largely because of the time and effort required for highly trained humans to manually score the images. Convoluted neural networks were recently developed that distinguish individual humans and objects in images. Here, we trained one of these networks, the InceptionV3 convolutional neural net, with a large set of human-scored mouse images...
January 2018: Molecular Pain
https://www.readbyqxmd.com/read/29546406/characteristics-of-combat-associated-small-bowel-injuries
#13
Mariya E Skube, Quinn Mallery, Elizabeth Lusczek, Joel Elterman, Mary A Spott, Greg J Beilman
Introduction: Although there are multiple studies regarding the management and outcomes of colonic injuries incurred in combat, the literature is limited with regard to small bowel injuries. This study seeks to provide the largest reported review of the characteristics of combat-associated small bowel injuries. Materials and Methods: The Department of Defense Trauma Registry was queried for U.S. Armed Forces members who sustained hollow viscus injuries in the years 2007-2012 during Operations Enduring Freedom, Iraqi Freedom, and New Dawn...
March 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29521830/human-derived-amniotic-membrane-is-associated-with-decreased-postoperative-intraperitoneal-adhesions-in-a-rat-model
#14
John P Kuckelman, Joseph Kononchik, Joshua Smith, Kevin R Kniery, Jeffrey T Kay, Zachary S Hoffer, Scott R Steele, Vance Sohn
BACKGROUND: Complications from adhesions after intra-abdominal surgery accounts for ~6% of hospital admissions. Currently, hyaluronate/carboxymethylcellulose represents the main option to prevent postoperative adhesion formation. Human amniotic membrane contains inherent anti-inflammatory properties that mitigate adhesion formation. OBJECTIVE: This study aimed to evaluate adhesion generation after surgical trauma with amniotic membranes compared with standard intraperitoneal adhesion barriers...
April 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29518504/can-recognition-of-spinal-ischemia-be-improved-application-of-motor-evoked-potentials-serum-markers-and-breath-gas-analysis-in-an-acutely-instrumented-pig-model
#15
Anja Püschel, Rasmus Ebel, Patricia Fuchs, Janet Hofmann, Jochen K Schubert, Jan P Roesner, Stefan Bergt, Andreas Wree, Brigitte Vollmar, Ernst Klar, Carsten M Bünger, Sabine Kischkel
BACKROUND: Paraplegia due to spinal cord ischemia (SCI) is a serious complication after repair of thoraco-abdominal aortic aneurysms. For prevention and early treatment of spinal ischemia intraoperative monitoring of spinal cord integrity is essential. This study was intended to improve recognition of SCI through a combination of transcranial motor-evoked potentials (tc-MEPs), serum markers and innovative breath analysis. METHODS: In nine female German landrace pigs, tc-MEPs were captured, markers of neuronal damage were determined in blood and volatile organic compounds (VOCs) were analysed in exhaled air...
March 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29485210/evaluation-of-potential-serum-biomarkers-of-hepatic-fibrosis-and-necroinflammatory-activity-in-dogs-with-liver-disease
#16
Chantel Raghu, Joanne Ekena, John M Cullen, Craig B Webb, Lauren A Trepanier
BACKGROUND: Serum interleukin 6 (IL-6), chemokine ligand 2 (CCL2), C-reactive protein (CRP), and the ratio of aspartate transaminase to alanine transaminase (AST:ALT) have been correlated with fibrosis and necroinflammatory activity in humans with various hepatopathies. HYPOTHESIS/OBJECTIVES: To determine whether increases in serum IL-6, CCL2, CRP, or AST:ALT were associated with moderate to severe fibrosis or necroinflammatory activity in dogs with various hepatopathies...
February 27, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29483377/laparoscopic-management-of-retroperitoneal-injuries-from-penetrating-abdominal-trauma-in-haemodynamically-stable-patients
#17
Modise Zacharia Koto, Oleh Y Matsevych, Fusi Mosai, Moses Balabyeki, Colleen Aldous
Background: Laparoscopy is increasingly utilised in the trauma setting. However, its safety and reliability in evaluating and managing retroperitoneal injuries are not known. Aim: The aim of this study was to analyse our experience with laparoscopic management of retroperitoneal injuries due to penetrating abdominal trauma (PAT) and to investigate its feasibility, safety and accuracy in haemodynamically stable patients. Methods: Over a 4-year period, patients approached laparoscopically with retroperitoneal injuries were analysed...
February 27, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29470527/value-of-diagnostic-and-therapeutic-laparoscopy-for-patients-with-blunt-abdominal-trauma-a-10-year-medical-center-experience
#18
Heng-Fu Lin, Ying-Da Chen, Shyr-Chyr Chen
Laparoscopy has been used for the diagnosis and treatment for hemodynamically stable patients with penetrating abdominal trauma. This study evaluated whether diagnostic and therapeutic laparoscopy can be used as effectively in select patients with blunt abdominal trauma. All hemodynamically stable patients undergoing operations for blunt abdominal trauma over a 10-year period (2006-2015) at a tertiary medical center were included. Patients undergoing laparotomy were categorized as group A. Patients who underwent laparoscopy were categorized as group B...
2018: PloS One
https://www.readbyqxmd.com/read/29461612/the-hyperthermic-intraoperative-intraperitoneal-chemotherapy-in-the-treatment-of-advanced-abdominopelvic-cancer-personal-experience-on-103-procedures-during-a-seventeen-year-period-in-a-single-italian-center
#19
D Di Miceli, C Cina, C Fiorillo, G B Doglietto, S Alfieri
OBJECTIVE: Integration of different therapeutic strategies in cancer surgery in the last years has led from treating primary lesions to the surgical treatment of metastases. The purpose of this paper is to report a single Italian center experience of treatment of peritoneal carcinosis of the abdominopelvic malignancies. PATIENTS AND METHODS: 103 HIPEC procedures were performed in 17 years on 94 selected patients affected by abdominopelvic cancer. The PCI score was calculated at laparotomy...
February 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29443788/a-prospective-randomized-open-label-controlled-study-investigating-the-efficiency-and-safety-of-3-different-methods-of-rectus-sheath-block-analgesia-following-midline-laparotomy
#20
Martin Purdy, Mari Kinnunen, Merja Kokki, Maarit Anttila, Matti Eskelinen, Heidi Hautajärvi, Marko Lehtonen, Hannu Kokki
BACKGROUND: There is a controversy regarding the efficacy of rectus sheath block (RSB). The aim of the present study was to evaluate analgesic efficacy and safety of three different methods of RSB in postoperative pain management after midline laparotomy. METHODS: A prospective, randomized, controlled, open-label clinical trial with 4 parallel groups was conducted in a tertiary care hospital in Finland. A total of 57 patients undergoing midline laparotomy were randomized to the control group (n = 12) or to 1 of the 3 active RSB analgesia groups: single-dose (n = 16), repeated-doses (n = 12), or continuous infusion (n = 17)...
February 2018: Medicine (Baltimore)
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