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https://www.readbyqxmd.com/read/28814930/comparing-lavage-of-the-peritoneal-cavity-with-lidocaine-bupivacaine-and-normal-saline-to-reduce-the-formation-of-abdominal-adhesion-bands-in-rats
#1
Hossein Parsa, Hengameh Saravani, Fatemeh Sameei-Rad, Marjan Nasiri, Zahra Farahaninik, Amirhossein Rahmani
BACKGROUND: Intra-abdominal adhesions are fibrous bands that develop after abdominal surgery or inflammation and cause mortality and morbidity following surgeries. This study aimed to assess the effects of bupivacaine, saline and two doses of lidocaine, after peritoneal lavage and to compare their effects in reducing abdominal adhesions in rat. METHODS: In a blinded, randomised, placebo-controlled clinical trial, 50 female rats were anaesthetised and the parietal peritoneum was scratched to induce punctate bleeding...
May 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28808225/congestive-preconditioning-by-portal-venous-clamping-a-novel-preventive-concept-for-small-intestinal-congestive-re-outflow-injury
#2
Hironori Hayashi, Hiroyuki Takamura, Ryosuke Gabata, Yoshinao Ohbatake, Shinichi Nakanuma, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya, Sachio Fushida, Tetsuo Ohta
BACKGROUND Congestion of the small intestine, which induces mucosal damage via apoptosis, is a common pathophysiological change in hepato-biliary-pancreatic surgery, including liver transplantation. Small intestinal mucosal damage can trigger postoperative complications via various pathways. Therefore, we investigated the efficacy of intermittent portal venous clamping, which we named congestive preconditioning (CPC), for decreasing congestive re-outflow injury (CRoI) of the small intestine. MATERIAL AND METHODS Small intestinal CRoI was induced in rats by clamping the portal vein (PV) for 30 min, followed by re-outflow...
August 15, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28800941/survival-and-safety-associated-with-aggressive-surgery-for-stage-iii-iv-epithelial-ovarian-cancer-a-single-institution-observation-study
#3
Shinichi Tate, Kazuyoshi Kato, Kyoko Nishikimi, Ayumu Matsuoka, Makio Shozu
OBJECTIVE: We evaluated the efficacy and safety of aggressive surgery for advanced ovarian cancer at a non-high-volume center. MATERIALS AND METHODS: We evaluated consecutive patients with stage III/IV ovarian, fallopian, and peritoneal cancer undergoing elective aggressive surgery from January 2008 to December 2012, which encompassed the first 5years after implementing an aggressive surgery protocol. After receiving appropriate training for 9months, a gynecological surgical team began performing multi-visceral resections...
August 8, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28796074/postoperative-characteristics-of-infants-who-developed-necrotizing-enterocolitis-with-different-postnatal-ages
#4
Xiaowen Li, Lei Li, Yan Wang, Chun Deng, Chunbao Guo
Our goal was to investigate the surgical procedures, postoperative complications, and survival with regard to different onset timing of necrotizing enterocolitis (NEC).We performed a retrospective review of medical records with a diagnosis of NEC between 2005 and 2016. The cutoff was set at 10 days for early onset ≤10 days and late onset over 10 days. Propensity score matching was performed to adjust for any baseline differences. In 53 paired patients, clinical outcomes, including, mortality, postoperative complications, and length of neonatal intensive care unit (NICU) stay, were evaluated on the basis of early or late-onset NEC...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28780836/-retrospectively-analysis-on-95-postpartum-hemorrhage-women-treated-with-obstetrics-and-gynecology-in-intensive-care-unit
#5
A J Pan, T J Yang, Q Mei, L Zhang, L Chen, D B Wu, B Liu
Objective: To review the clinical aspects and pathogenesis of postpartum hemorrhage (PPH) and investigate the optimal protocols for intervention. Methods: From February 2009 to December 2015, data of normal labour and casearean birth women admitted to intensive care unit (ICU) in our hospital because of hematobilia were selected. 95 patients were divided into three groups (e. g ≥500-1 000 ml, ≥1 000-1 500 ml, ≥1 500-2 500 ml and ≥2 500 ml group) according to the bleeding volume. A retrospective analysis was performed to study the pathogenesis of PPH, organ function, surgical intervention and clinical prognosis on hemorrhage...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28762447/protective-effects-of-dexmedetomidine-and-remote-ischemic-preconditioning-on-renal-ischemia-reperfusion-injury-in-rats
#6
Cansu Balcı, Mert Akan, Nilay Boztaş, Sevda Özkardeşler, Bekir Uğur Ergür, Mustafa Ensari Güneli, Belgin Ünal
BACKGROUND: The aim of this study was to evaluate the effects of remote ischemic preconditioning (RIPC) and dexmedetomidine as pharmacological conditioning in a rat renal ischemia/reperfusion (IR) injury model. METHODS: Total of 28 male Wistar Albino rats weighing 250 to 300 g were divided into 4 equal groups. Group I (Sham; n=7): Laparotomy and renal pedicle dissection were performed, and the rats were observed under anesthesia without any intervention. Group II (IR; n=7): Following laparotomy and 45 minutes of left renal pedicle occlusion, 4 hours of reperfusion was performed...
July 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28757438/does-the-difference-in-fascial-closure-technique-affect-post-operative-pain
#7
Anna Lyapis, Amanda Ulrich, Rachel LaMonica, Chia-Ling Kuo, Leak Kaye, Danielle Luciano
STUDY OBJECTIVE: To compare post-operative incisional pain on post-operative days 1 and 14 when utilizing fascial closure device (FCD) versus traditional fascial closure (TFC) of the 12mm upper quadrant port during robotic surgery. Time required to close the incision was also compared. DESIGN: Randomized controlled trial DESIGN CLASSIFICATION: Clinical study, Canadian task force class I SETTING: Two academic affiliated hospitals- The Hospital of Central Connecticut and The University of Connecticut PATIENTS: Women undergoing robotic surgery for benign indications by minimally invasive gynecologists at our institutions between 11/2012 and 10/2014 were enrolled in the study at their preoperative visit...
July 27, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28746186/laparoscopic-based-score-assessment-combined-with-a-multiple-disciplinary-team-in-management-of-recurrent-ovarian-cancer-a-single-center-prospective-study-for-personalized-surgical-therapy
#8
Weihong Yang, Zhongping Cheng, Hong Dai, Changchun Long, Hailun Liu
The aim of the study was to evaluate the effect of laparoscopic-based score combined with a multiple disciplinary team (MDT) for predicting optimal cytoreduction and perform personalized surgical treatment in recurrent ovarian cancer (ROC).The study is a single-center, prospective investigation. From March 2013 to May 2015, the consecutive treated patients with platinum-sensitive ROC were collected in Yangpu Hospital. The appropriated patients were enrolled into the study to perform the laparoscopic-based PIV (predictive index value) score assessment with an MDT for predicting optimal cytoreduction...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28740960/prognostic-factors-in-patients-with-acute-mesenteric-ischemia
#9
Doğan Yıldırım, Adnan Hut, Cihad Tatar, Turgut Dönmez, Muzaffer Akıncı, Mehmet Toptaş
OBJECTIVE: Acute mesenteric ischemia, one of the causes of acute abdominal pain due to occlusion of the superior mesenteric artery, has a fatal course as a result of intestinal necrosis. There is no specific laboratory test to diagnose acute mesenteric ischemia. The basis of treatment in cases of acute mesenteric ischemia is composed of early diagnosis, resection of intestinal sections with infarction, regulation of intestinal blood flow, second look laparotomy when required, and intensive care support...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28738942/in-the-modern-era-of-ct-do-blunt-trauma-patients-with-markers-for-blunt-bowel-or-mesenteric-injury-still-require-exploratory-laparotomy
#10
Katelyn Young, Melina Benson, Andrew Higgins, James Dove, Marie Hunsinger, Mohsen Shabahang, Joseph Blansfield, Denise Torres, Kenneth Widom, Jeffrey Wild
After blunt trauma, certain CT markers, such as free intraperitoneal air, strongly suggest bowel perforation, whereas other markers, including free intraperitoneal fluid without solid organ injury, may be merely suspicious for acute injury. The present study aims to delineate the safety of nonoperative management for markers of blunt bowel or mesenteric injury (BBMI) that are suspicious for significant bowel injury after blunt trauma. This was a retrospective review of adult blunt trauma patients with abdominopelvic CT scans on admission to a Level I trauma center between 2012 and 2014...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28735116/surgical-technique-of-percutaneous-iliosacral-screw-fixation-in-s3-level-in-unstable-pelvic-fracture-with-closed-degloving-injury-and-morrell-lavallee-lesion-two-case-reports
#11
Ismail H Dilogo, Jessica Fiolin
INTRODUCTION: Percutaneous screw fixation is considered the best option in unstable pelvic fracture with severe soft tissue injury. However, fixation technique at the level of S3 has not been well established. This paper showed the feasible surgical technique of S3 screw insertion in unstable pelvic fracture with severe soft tissue injury. METHODS: We reported 2 cases of unstable pelvic injury of an 11 years old boy with Marvin-Tile (MT) C1 pelvic fracture with sacroiliac (SI) joint disruption, skin avulsion and Morel-Lavallée lesion...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28729125/comparative-effects-of-vitamin-d-and-methylprednisolone-against-ischemia-reperfusion-injury-of-rabbit-spinal-cords
#12
Bora Gürer, Abdullah Karakoç, Pınar Kuru Bektaşoğlu, Hayri Kertmen, Mehmet Ali Kanat, Ata Türker Arıkök, Berrin İmge Ergüder, Mustafa Fevzi Sargon, Özden Çağlar Öztürk, Erhan Çelikoğlu
INTRODUCTION: Recent studies have demonstrated the neuroprotective and immunomodulatory effects of 1,25-dihydroxyvitamin D3 (calcitriol), but no previous study has examined these effects on spinal cord ischemia/reperfusion (I/R) injury. Therefore, the present study aimed to evaluate whether calcitriol protects the spinal cord from I/R injury. METHODS: Rabbits were randomized into four groups of eight animals: group 1 (laparotomy control), group 2 (ischemia control), group 3 (30mg/kg intraperitoneal methylprednisolone at surgery), and group 4 (0...
July 18, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28718038/reappraisal-of-staging-laparoscopy-for-patients-with-pancreatic-adenocarcinoma-a-contemporary-analysis-of-1001-patients
#13
Zhi Ven Fong, Donna Marie L Alvino, Carlos Fernández-Del Castillo, Winta T Mehtsun, Ilaria Pergolini, Andrew L Warshaw, David C Chang, Keith D Lillemoe, Cristina R Ferrone
BACKGROUND: Recent advances in imaging and the increasing use of neoadjuvant therapy puts the contemporary utility of staging laparoscopy for patients with pancreatic adenocarcinoma (PDAC) into question. This study aimed to develop a prognostic score to optimize prevention of an unnecessary laparotomy and minimize the rate for unnecessary laparoscopy. METHODS: Clinicopathologic data were evaluated for all patients undergoing surgical intervention for PDAC between 2001 and 2015, who were stratified into group 1 (2001-2008) and group 2 (2009-2014)...
July 17, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28706891/evaluation-of-botulinum-toxin-type-a-effectiveness-in-preventing-postoperative-intraperitoneal-adhesions
#14
Mehmet Dokur, Erdal Uysal
PURPOSE: Postoperative intraperitoneal adhesions (PIAs) are one of the most important problems surgeons have to face after laparotomies. In this study, we aimed to evaluate the effectiveness of local application of botulinum toxin type A (BoNT-A) in various dosages on the prevention of intra-abdominal adhesions in rats with experimental intra-abdominal adhesions. METHODS: Forty Wistar Albino female rats were randomly separated into 4 groups. The 4 groups were determined as follows: Control (group 1, n = 10); Sham (group 2, n = 10); 10-µg/kg low-dose BoNT-A (group 3, n = 10) and 30-µg/kg high-dose BoNT-A (group 4, n = 10)...
July 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28706425/procalcitionin-as-a-diagnostic-marker-to-distinguish-upper-and-lower-gastrointestinal-perforation
#15
Yang Gao, Kai-Jiang Yu, Kai Kang, Hai-Tao Liu, Xing Zhang, Rui Huang, Jing-Dong Qu, Si-Cong Wang, Rui-Jin Liu, Yan-Song Liu, Hong-Liang Wang
AIM: To assess the accuracy of serum procalcitionin (PCT) as a diagnostic marker in verifying upper and lower gastrointestinal perforation (GIP). METHODS: This retrospective study included 46 patients from the surgical intensive care unit (ICU) of the Second Affiliated Hospital of Harbin Medical University who were confirmed to have GIP between June 2013 and December 2016. Demographic and clinical patient data were recorded on admission to ICU. Patients were divided into upper (n = 19) and lower (n = 27) GIP groups according to the perforation site (above or below Treitz ligament)...
June 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28700426/coexisting-primary-ovarian-and-omental-hydatid-disease-mimicking-an-ovarian-neoplasm-a-case-report
#16
Emre E Tas, Gulin F Yegin Akcay, Fatma Yildirim, Filiz Yavuz
Hydatid disease is a parasitic infection that most commonly affects the liver and lungs, although the disease can arise in any part of the body. Cysts may mimic many benign and malignant conditions. The diagnosis cannot be confirmed preoperatively in all cases. A 44-yr-old menopausal woman was admitted to the department of gynecology with complaints of abdominal distention. A fixed abdominopelvic mass was identified. Radiology revealed a 20-cm mass with branched septations and solid components. CA-125 level was 55 kU/L, and Risk of Malignancy Index-2 score was 880...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28694568/the-role-of-routine-measurement-of-intra-abdominal-pressure-in-preventing-abdominal-compartment-syndrome
#17
G Raghavendra Prasad, J V Subba Rao, Amtul Aziz, T M Rashmi
INTRODUCTION: Abdomen, a closed compartment, is prone to raised intra-abdominal pressure (IAP) in the postoperative period. After a critical value of ≥ 15 cm of water, IAP produces abdominal compartment syndrome (ACS). ACS leads to reduced venous return, reduced cardiac output, and domino effect of organ dysfunction, leading to death. Hence, it is the need of hour to monitor IAP to pick up intra-abdominal hypertension (IAH) and ACS. This routine facilitates early institution of treatment measures...
July 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28682130/the-front-line-general-surgery-consultant-as-a-new-model-of-emergency-care
#18
A P Navarro, Ejo Hardy, B Oakley, E Mohamed, N T Welch, S L Parsons
INTRODUCTION Emergency general surgery services in England are undergoing rapid structural change with the aim of improving care. In our centre, the key issues identified were high numbers of admissions, inappropriate referrals, prolonged waiting times, delayed senior input and poor patient satisfaction. A new model was launched in January 2015 to address these issues: the surgical triage unit (STU). This study assesses the success of the new service. METHODS All emergency general surgical admissions during a five-month period before introduction of the STU were compared with those of a comparable five-month period after its introduction...
July 6, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28679359/bilateral-thoracic-paravertebral-block-for-immediate-postoperative-pain-relief-in-the-pacu-a-prospective-observational-study
#19
Fei Liu, HuanKai Zhang, Yunxia Zuo
BACKGROUND: To investigate the feasibility, effectiveness and safety of bilateral thoracic paravertebral block (TPVB) in the post anesthesia care unit (PACU) for pain relief in participants after laparotomy. METHODS: A single shot of bilateral TPVB with 25 ml of 0.2% ropivacaine and 5 mg dexamethasone in combination for both sides at the 8th thoracic transverse level (T8) was performed on 201 participants who complained moderate to severe pain on arrival to PACU after laparotomy...
July 5, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28678652/postoperative-c-reactive-protein-concentration-and-clinical-outcome-comparison-of-open-cystectomy-to-robot-assisted-laparoscopic-cystectomy-with-extracorporeal-or-intracorporeal-urinary-diversion-in-a-prospective-study
#20
Pernille Skjold Kingo, Rikke Nørregaard, Michael Borre, Jørgen Bjerggaard Jensen
OBJECTIVE: This study aimed to compare clinical outcome and postoperative systemic inflammatory response using C-reactive protein (CRP) levels, to quantify the degree of tissue injury in open mini-laparotomy cystectomy (OMC) versus robot-assisted laparoscopic cystectomy with extracorporeal (RALC-EUD) or intracorporeal urinary diversion (RALC-IUD). MATERIALS AND METHODS: From September 2012 to September 2015, 309 patients diagnosed with bladder cancer underwent radical cystectomy with urinary diversion...
July 5, 2017: Scandinavian Journal of Urology
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