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https://www.readbyqxmd.com/read/29648939/reversal-of-schistosome-resistance-in-biomphalaria-glabrata-by-heat-shock-may-be-dependent-on-snail-genotype
#1
John Sullivan
Several genes have recently been shown to affect the innate resistance of laboratory strains of Biomphalaria glabrata to infection with Schistosoma mansoni, including Hsp90, expression of which following a brief exposure to elevated temperature can interfere with resistance in juvenile BS-90 snails. Because a prior study failed to see a similar effect in adult snails, juvenile BS-90 snails were exposed to 10 or 50 miracidia following a 4.5 to 6-hr incubation at 33 C or 37 C. Snails were then monitored for production of secondary sporocysts or release of cercariae...
April 12, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29568198/comparative-molluscicidal-and-schistosomicidal-potentiality-of-two-solanum-species-and-its-isolated-glycoalkaloids
#2
Muhammad A Alsherbiny, Shymaa A El Badawy, Hesham Elbedewy, Shahira M Ezzat, Fatma S Elsakhawy, Mostafa A Abdel-Kawy
Schistosomiasis is the most noteworthy parasitic disease after malaria. Furthermore, the significant activity of the genus Solanum against Schistosoma worms and its intermediate host snails reinforced the study of Solanum seaforthianum Andr. (SS) and Solanum macrocarpon L. (SM) for their molluscicidal and schistosomicidal potentiality. In this study, different extracts, fractions and isolated compounds of both Solanum species are evaluated for the molluscicidal and schistosomicidal potentialities. The niclosamide was used as positive molluscicide control against Biomphalaria alexandrina snails...
January 2018: Pharmacognosy Research
https://www.readbyqxmd.com/read/29566237/allelic-variation-in-a-single-genomic-region-alters-the-microbiome-of-the-snail-biomphalaria-glabrata
#3
Euan R O Allan, Jacob A Tennessen, Thomas J Sharpton, Michael S Blouin
Freshwater snails are the intermediate hosts for numerous parasitic worms which can have negative consequences for human health and agriculture. Understanding the transmission of these diseases requires a more complete characterization of the immunobiology of snail hosts. This includes the characterization of its microbiome and genetic factors which may interact with this important commensal community. Allelic variation in the Guadeloupe Resistance Complex (GRC) genomic region of Guadeloupean Biomphalaria glabrata influences their susceptibility to schistosome infection, and may have other roles in the snail immune response...
March 16, 2018: Journal of Heredity
https://www.readbyqxmd.com/read/29551000/spatial-distribution-and-seasonality-of-biomphalaria-spp-in-s%C3%A3-o-lu%C3%A3-s-maranh%C3%A3-o-brazil
#4
Nathalia Ferreira David, Selma Patrícia Diniz Cantanhede, Natanael Bezerra Monroe, Luciana Patrícia Lima Alves Pereira, Nêuton Silva-Souza, Ana Lúcia Abreu-Silva, Verônica Maria de Oliveira, Ligia Tchaicka
Two of the three vector species of Schistosoma mansoni Sambon, 1907 in Brazil occur in the state of Maranhão: Biomphalaria glabrata (Say, 1818) and Biomphalaria straminea (Dunker, 1848). For the implementation of effective measures to combat schistosomiasis, it is necessary to identify the spatial and seasonal dynamics of these snails. Therefore, this work brought together information from malacological survey carried out in São Luís (Maranhão, Brazil) to identify the spatial and seasonal distribution patterns of Biomphalaria spp...
March 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29545305/complete-genome-sequence-of-pittsburgh-sewage-associated-virus-1
#5
Paul G Cantalupo, James M Pipas
We present the complete genome sequence of a virus found in raw sewage collected in Pittsburgh, PA, USA. Pittsburgh sewage-associated virus 1 (PSAV1) encodes one large open reading frame with conserved domains typically found in the Picornavirales order of viruses. PSAV1 is closely related to Biomphalaria virus 2 (BV2).
March 15, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29534740/biomphalaria-camerunensis-as-a-viable-alternative-intermediate-host-for-schistosoma-mansoni-in-southern-cameroon
#6
Alvine C Kengne-Fokam, Hugues C Nana-Djeunga, Mohamed Bagayan, Flobert Njiokou
BACKGROUND: Intestinal schistosomiasis due to Schistosoma mansoni was mapped in Cameroon in the 1990s and preventive chemotherapy launched since 2005. A situation analysis conducted in 2011 revealed an increase in schistosomiasis transmission, especially in the equatorial part of the country, despite the fact that Biomphalaria pfeifferi, the main intermediate host of this parasite, is now scarce in many foci. Biomphalaria camerunensis, restricted to the equatorial part of the country, is considered as a less suitable host for S...
March 13, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29534072/a-field-survey-using-lamp-assay-for-detection-of-schistosoma-mansoni-in-a-low-transmission-area-of-schistosomiasis-in-umbuzeiro-brazil-assessment-in-human-and-snail-samples
#7
Javier Gandasegui, Pedro Fernández-Soto, Antonio Muro, Constança Simões Barbosa, Fabio Lopes de Melo, Rodrigo Loyo, Elainne Christine de Souza Gomes
BACKGROUND: In Brazil, schistosomiasis is a parasitic disease of public health relevance, mainly in poor areas where Schistosoma mansoni is the only human species encountered and Biomphalaria straminea is one of the intermediate host snails. A nested-PCR based on a specific mitochondrial S. mansoni minisatellite DNA region has been successfully developed and applied as a reference method in Brazil for S. mansoni detection, mainly in host snails for epidemiological studies. The amplification efficiency of LAMP is known to be higher than PCR...
March 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29469526/-density-and-hydrostatic-settling-velocity-of-biomphalaria-straminea
#8
Min Feng-Yang, Wang Jia-Sheng, Xu Xing-Jian, Zhou Jian-Yin, Chen Li-Zhen
OBJECTIVE: To understand the eco-hydraulics characteristics of Biomphalaria straminea , the intermediate host of Schistosoma mansoni . METHODS: The drainage method and settlement tube method were applied to measure B. straminea 's density and hydrostatic settling velocity respectively. RESULTS: The density of B. straminea was 1.04-1.16 g/cm3 , and the average value was 1.08 g/cm3 . The hydrostatic settling velocity was 2.32-12.92 cm/s. CONCLUSIONS: The eco-hydraulics characteristics of B...
May 18, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469321/-identification-of-a-myeloid-differentiation-factor-88-myd88-in-oncomelania-hupensis-against-schistosoma-japonicum-infection
#9
Gao Qian, Li Yan-Wei, Huang Wen-Ling, Zhao Qin-Ping, Dong Hui-Fen
OBJECTIVE: To identify a myeloid differentiation factor 88 (MyD88) in Oncomelania hupensis , and characterize the role of MyD88 against Schistosoma japonicum infection. METHODS: The complete cDNA of MyD88 in O. hupensis was obtained by using rapid amplification of cDNA ends (RACE), and homologues sequences and conserved domains were aligned and the structure of MyD88 was predicted either. A phylogenetic tree of MyD88 was further constructed with other species. In addition, the mRNA expression level of O...
March 1, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29451595/evaluation-of-molluscicidal-activity-of-three-mangrove-species-avicennia-schaueriana-laguncularia-racemosa-and-rhizophora-mangle-and-their-effects-on-the-bioactivity-of-biomphalaria-glabrata-say-1818
#10
Renato Juvino de Aragão Mendes, Adalberto Alves Pereira Filho, Aline de Jesus Lustosa Nogueira, Karla Regina Freitas Araújo, Clícia Rosane Costa França, Iramar Borba de Carvalho, Natale Maria Lindoso da Silva, Alexandre Santana Azevedo, Ivone Garros Rosa
Schistosomiasis is a disease of global extent reaching populations in social vulnerability. One of the control measures of this parasitosis is the use of molluscicidal substances that can fight snails of the genus Biomphalaria, intermediate hosts of Schistosoma mansoni. The aim of this work was to study the toxic activity of three mangrove species (Avicennia schaueriana Stapf. & Leech, ex Moldenke, 1939, Laguncularia racemosa (L.) CF Gaertn, 1807 and Rhizophora mangle L. 1753) on the biological activities of snails Biomphalaria glabrata...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29409884/identification-of-toll-like-receptor-family-members-in-oncomelania-hupensis-and-their-role-in-defense-against-schistosoma-japonicum
#11
Qin Ping Zhao, Qian Gao, Yan Zhang, Yan Wei Li, Wen Ling Huang, Chun-Lian Tang, Hui Fen Dong
The amphibious snail, Oncomelania hupensis, primarily distributed in the Far East, is the only intermediate host of Schistosoma japonicum, which causes the most virulent form of schistosomiasis. Obligatory parasitism of snails is the main vehicle for human and livestock infection and depends primarily on parasite infectivity, snail defense capacity and specificity, and parasite-snail compatibility. Therefore, the schistosome-snail interaction is biomedically significant, particularly the molecular mechanisms involved in the innate immune response against S...
January 30, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29319750/biological-screening-of-extracts-from-leaf-and-stem-bark-of-croton-floribundus-spreng-euphorbiaceae
#12
E F Barth, L S Pinto, P Dileli, D C Biavatti, Y L Silva, W Bortolucci, Z C Gazim, O S Takemura, M B Romagnolo, A Laverde-Junior
This work describes the preliminary evaluation of cytotoxic, antimicrobial, molluscicidal, antioxidant and anticholinesterase activities from leaf (LECF) and stem bark alcoholic extracts (BECF) of the species Croton floribundus Spreng. (Euphorbiaceae), popularly known as capixingui or tapixingui. BECF presented significant toxicity (LC50 = 89.6 μg/ml) in the Artemia salina Leach, 1819 (Crustacea: Branchiopoda) bioassay, whereas LECF did not show activity (LC50 > 1000 μg/ml). From DPPH method, the values of IC50 for the LECF and BECF were 61...
January 8, 2018: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29239570/spatial-analysis-of-the-prevalence-of-schistosomiasis-in-an-endemic-coastal-area-in-north-eastern-brazil
#13
Allan D Santos, Jonhnatas Silva, Ana Caroline Lima, Márcio Santos, Shirley Lima, Monalisa Amor, Carlos Santos, Arthur Vasconcelos, Silvio Dolabella, Karina C G M Araújo
Due to contact and misuse of water drainage channels, schistosomiasis has spread and become a constant concern in northeastern Brazil. The aim of this study was to monitor human cases of Schistosomiasis mansoni and the breeding areas of the snail intermediate host Biomphalaria glabrata through spatial analysis in a community named Invasão do Canal do Guaxinim, located in Barra dos Coqueiros City in an endemic coastal part of the state of Sergipe, Brazil. This research was performed as a cross-sectional epidemiological study conducted with parasitological and malacological surveys...
November 27, 2017: Geospatial Health
https://www.readbyqxmd.com/read/29228974/central-nervous-system-transcriptome-of-biomphalaria-alexandrina-an-intermediate-host-for-schistosomiasis
#14
Tamer A Mansour, Mohamed R Habib, Laura C Vicente Rodríguez, Anthony Hernández Vázquez, Julián Maldonado Alers, Alfredo Ghezzi, Roger P Croll, C Titus Brown, Mark W Miller
OBJECTIVE: Globally, more than 200 million people live at risk of the neglected tropical disease schistosomiasis (or snail fever). Larval schistosomes require the presence of specific snail species that act as intermediate hosts, supporting their multiplication and transformation into forms that can infect humans. This project was designed to generate a transcriptome from the central nervous system (CNS) of Biomphalaria alexandrina, the major intermediate host for Schistosoma mansoni in Egypt...
December 11, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29196196/molluscicidal-activity-of-manilkara-subsericea-mart-dubard-on-biomphalaria-glabrata-say-1818
#15
Robson Xavier Faria, Leandro Machado Rocha, Eloísa Portugal Barros Silva Soares Souza, Fernanda Borges Almeida, Caio Pinho Fernandes, José Augusto Albuquerque Santos
Schistosomiasis is promoted for species from Schistosoma genus affecting over 200 million people worldwide. Molluscicides are an efficient method to control this disease, being able to reduce intermediate host snail Biomphalaria glabrata number. In function of resistance cases using niclosamide, natural products are promisors to discover new drugs. Manilkara subsericea is endemic to Brazilian sandbanks of Rio de Janeiro State and wide ranges of biological activities. However, there is no studies evaluating its effects as molluscicidal agent...
February 2018: Acta Tropica
https://www.readbyqxmd.com/read/29183853/toxicity-of-usnic-acid-from-cladonia-substellata-lichen-to-embryos-and-adults-of-biomphalaria-glabrata
#16
Hallysson D A Araújo, Luanna R S Silva, Williams N Siqueira, Caíque S M Fonseca, Nicácio H Silva, Ana M M A Melo, Mônica C B Martins, Vera L M Lima
This study reports the molluscicidal activity of usnic acid isolated from Cladonia substellata Vanio (lichen) on embryos at various stages of development and in adult mollusks of Biomphalaria glabrata. The toxicity of usnic acid was also evaluated through Artemia salina larvae mortality. Usnic acid was extracted with diethyl ether, isolated, purified, and its structure confirmed by analyzing the spectra of proton nuclear magnetic resonance. LC90 for 24 h of exposure were 1.62, 4.45, 5.36, and 4.49 μg mL-1 for blastula, gastrula, trocophore, and veliger embryonic stages, respectively, and 3...
March 2018: Acta Tropica
https://www.readbyqxmd.com/read/29169384/assessing-s-mansoni-prevalence-in-biomphalaria-snails-in-the-gombe-ecosystem-of-western-tanzania-the-importance-of-dna-sequence-data-for-clarifying-species-identification
#17
Jared S Bakuza, Robert Gillespie, Gamba Nkwengulila, Aileen Adam, Elizabeth Kilbride, Barbara K Mable
BACKGROUND: Snails are essential for the transmission and maintenance of schistosomiasis in endemic areas, as they serve as intermediate hosts for schistosome parasites. A clear understanding of the snail species present, their local distribution and infection status is therefore a prerequisite for effective control of schistosomiasis. The purpose of this study was to establish the infection status and distribution of Schistosoma mansoni in snails in the Gombe area along the shores of Lake Tanganyika in western Tanzania, using both detection of cercarial shedding and molecular approaches...
November 23, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29166439/the-geographic-information-system-applied-to-study-schistosomiasis-in-pernambuco
#18
Verônica Santos Barbosa, Rodrigo Moraes Loyo, Ricardo José de Paula Souza E Guimarães, Constança Simões Barbosa
OBJECTIVE: Diagnose risk environments for schistosomiasis in coastal localities of Pernambuco using geoprocessing techniques. METHODS: A coproscopic and malacological survey were carried out in the Forte Orange and Serrambi areas. Environmental variables (temperature, salinity, pH, total dissolved solids and water fecal coliform dosage) were collected from Biomphalaria breeding sites or foci. The spatial analysis was performed using ArcGis 10.1 software, applying the kernel estimator, elevation map, and distance map...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29137971/clearance-of-schistosome-parasites-by-resistant-genotypes-at-a-single-genomic-region-in-biomphalaria-glabrata-snails-involves-cellular-components-of-the-hemolymph
#19
Euan R O Allan, Benjamin Gourbal, Camila B Dores, Anais Portet, Christopher J Bayne, Michael S Blouin
Schistosomiasis is one of the most detrimental neglected tropical diseases. Controlling the spread of this parasitic illness requires effective sanitation, access to chemotherapeutic drugs, and control over populations of the freshwater snails, such as Biomphalaria glabrata, that are essential intermediate hosts for schistosomes. Effectively controlling this disease, while minimising ecological implications of such control, will require an extensive understanding of the immunological interactions between schistosomes and their molluscan intermediate hosts...
November 12, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/29127867/effects-of-ashes-from-a-brazilian-savanna-wildfire-on-water-soil-and-biota-an-ecotoxicological-approach
#20
Eduardo C Oliveira-Filho, Darlan Q Brito, Zelia M B Dias, Mayara S Guarieiro, Esther L Carvalho, Maria L Fascineli, Cintia C Niva, Cesar K Grisolia
Wildfire is very common in Brazilian savannas, and its effects on water, soil and aquatic/soil organisms are poorly understood. In this study, we observed the effects of fire, especially of ashes, on surface soil and subsurface water in a typical Brazilian savanna (Cerrado sensu strictu) for one year. Soil analyses (pH, organic matter content, potential acidity, K, Ca, Mg and P) and subsurface water analyses (NO(3-), PO4(3-) Mg(2+), Ca(2+) and K(+)) were assessed. We evaluated the ecotoxicological effects of ashes on three different endpoints and species, in fish Danio rerio (embryonic development), aquatic snail Biomphalaria glabrata (reproduction) and a soil species Enchytraeus sp...
November 8, 2017: Science of the Total Environment
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