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Keywords Medical presentations of psych...

Medical presentations of psychiatric disease

https://read.qxmd.com/read/38486258/a-mixed-method-study-on-the-impact-of-covid-19-on-mental-healthcare-in-ghana-rethinking-mental-health-service-delivery
#1
JOURNAL ARTICLE
Michael Zobi, Seth Kofi Abrokwa, Eugene Dordoye, Angel Phuti
BACKGROUND: Since its emergence, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused severe health, social and economic challenges. Mental healthcare has been significantly affected globally, and even worse in developing countries. An emerging economy like Ghana in West Africa was not spared its disruptive effects. This study aimed to elucidate the impact of the coronavirus disease 2019, the COVID-19 pandemic (caused by SARS-CoV-2), on Ghana's mental healthcare system...
March 14, 2024: International Journal for Equity in Health
https://read.qxmd.com/read/38469206/clinical-characteristics-of-asymptomatic-thromboembolism-in-psychiatric-inpatients-a-retrospective-study
#2
JOURNAL ARTICLE
Yimeng Geng, Peifen Zhang, Yanmeng Pan, Huaizhi Wang, Yi Chen, Jianbo Lai, Shaohua Hu
PURPOSE: Venous thromboembolism (VTE) poses a significant threat to individuals' health, yet its correlation with mental disorders remains underappreciated. Here, we conducted a retrospective analysis to explore the characteristics of psychiatric patients presenting with VTE. METHODS: We retrospectively analyzed psychiatric inpatients with elevated plasma D-dimer levels at the Mental Health Center, First Affiliated Hospital, Zhejiang University School of Medicine, from January 2014 to January 2022...
2024: Neuropsychiatric Disease and Treatment
https://read.qxmd.com/read/38463061/wilson-s-disease-causing-acute-onset-of-optic-neuropathy-in-a-child-a-case-report-and-literature-review
#3
Ammar Albostani, Hamza Warda, Fares Alhashemi, Manar Rajabieh, Mohammed Abdulrazzak, Muhamad Kanjo
INTRODUCTION AND IMPORTANCE: Wilson disease (WD) is a rare genetic disorder with a wide range of clinical manifestations, including hepatic, neurologic, and psychiatric symptoms. To date, there have been five cases (including our case) representing optic neuropathy caused by WD. CASE PRESENTATION: A 15-year-old female presented to the emergency department with neurological symptoms. The patient exhibited confusion but maintained stable vital signs, and physical examinations were all normal...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38461125/drug-resistant-juvenile-myoclonic-epilepsy-a-literature-review
#4
REVIEW
A Nica
The ILAE's Task Force on Nosology and Definitions revised in 2022 its definition of juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy disorder, but this definition may well change again in the future. Although good drug response could almost be a diagnostic criterion for JME, drug resistance (DR) is observed in up to a third of patients. It is important to distinguish this from pseudoresistance, which is often linked to psychosocial problems or psychiatric comorbidities. After summarizing these aspects and the various definitions applied to JME, the present review lists the risk factors for DR-JME that have been identified in numerous studies and meta-analyses...
March 8, 2024: Revue Neurologique
https://read.qxmd.com/read/38454895/the-night-and-day-challenge-of-sleep-disorders-and-insomnia-a-narrative-review
#5
REVIEW
Luis San, Belén Arranz
This is a narrative review of sleep disorders, especially chronic insomnia, as a primary diagnosis or as a comorbid diagnosis associated with different psychiatric and organic diseases. The epidemiological evidence is reviewed, the diagnostic criteria most frequently used in clinical practice are examined, and a series of therapeutic recommendations for the correct treatment of this pathology is presented. Sleep disorders are very prevalent in the general population (one-third experiences difficulty with sleep initiation/maintenance at least once a week, and about 6-15% meet the criteria for insomnia disorders), but remain relatively poorly understood and frequently overlooked by healthcare professionals...
February 2024: Actas Españolas de Psiquiatría
https://read.qxmd.com/read/38454589/fixed-drug-combination-levosulpiride-and-rabeprazole-induced-atypical-parkinsonian-s-disorders-with-associated-anxiety-and-low-lying-depression
#6
JOURNAL ARTICLE
Vishal R Tandon, Sheikh Hanan Ismail, Amarjeet Singh
We hereby describe a rare case of levosulpiride-induced atypical parkinsonism presenting with sluggish movements, atypical kinetic tremors (tremors with voluntary movement), periorbital tremors, dystonia, difficulty in speech and coordination, postural imbalance, with additional features of difficulty in swallowing and drooling with associated recent onset psychiatric disturbances such as anxiety and low-lying depression. The dechallenge of levosulpiride and medications for associated anxiety and low-lying depression caused a complete remission of the disease within 2 ½ months...
January 1, 2024: Indian Journal of Pharmacology
https://read.qxmd.com/read/38453230/case-of-tizanidine-withdrawal-showing-hallucination-decorticate-posture-and-tremor-with-hypersympathetic-vital-signs
#7
JOURNAL ARTICLE
Jun Tanimura, Takao Hashimoto
Tizanidine, an α2-adrenergic receptor agonist commonly prescribed as a muscle relaxant, has been associated with limited cases of acute intoxication or withdrawal. Here, we present a case of tizanidine withdrawal in a woman in her 40s who presented with an unusual combination of systemic and neurological symptoms. These included hallucinations, decorticate posture, limb and eyelid tremors, along with hypertension, tachycardia and tachypnoea. The diagnosis of tizanidine withdrawal was established by a comprehensive assessment of the patient's medical history and the systematic exclusion of other potential diseases...
March 7, 2024: BMJ Case Reports
https://read.qxmd.com/read/38451668/a-medical-and-neuropsychiatric-management-survey-in-a-brazilian-cohort-of-patients-with-inflammatory-bowel-disease-ibd
#8
JOURNAL ARTICLE
Antônio Miguel Furtado Leitão, José Lopes Tabatinga Neto, Marcellus Henrique Loiola Ponte de Souza, Lúcia Libanez Bessa Campelo Braga, Francisco de Assis Aquino Gondim
BACKGROUND: Inflammatory bowel disease (IBD) can be accompanied by several neurological disorders. Since 2004, we started a Brazilian cohort to assess neuropsychiatric complications in IBD patients. Changes in therapeutic strategy and differences in the prevalence and relevance of neuropsychiatric disorders have been reported in the literature. We conducted a short patient-reported survey about the medical management of IBD (with a special focus on neuropsychiatric management) and its complications...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38443835/opportunistic-screening-for-copd-among-socially-marginalized-patients
#9
JOURNAL ARTICLE
Nina Brünés, Mette Bendtz Lindstroem, Charlotte Suppli Ulrik, Ove Andersen, Marianne Lisby, Nina Skavlan Godtfredsen, Tina Leth Hansen, Charlotta Pisinger, Vibeke Graven, Kristoffer Marsaa, Laura Hohwü Thomsen
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common disease associated with premature death. Tobacco exposure is the main risk factor, but lower socioeconomic status, early life insults, and occupational exposures are also important risk factors. Socially marginalized people, facing homelessness, substance use disorder, and mental illness, are likely to have a higher risk of developing COPD, and, furthermore, experience barriers to healthcare access and consequently poorer outcomes...
March 5, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38433412/diabetic-ketoacidosis-associated-with-second-generation-antipsychotics-a-case-study-and-review-of-literature
#10
JOURNAL ARTICLE
Heewon Bae, Ji Hyun Lee, Sungsuk Je, Seung-Hoon Lee, Hayun Choi
OBJECTIVE: Second-generation antipsychotics (SGAs) have revolutionized the treatment of psychiatric disorders, but are associated with significant metabolic risks, including diabetes and hyperglycemic crises. This review explores the complex interplay between antipsychotics, diabetes, and hyperglycemic crises, highlighting the mechanisms underlying SGA-induced diabetes. METHODS: We present the case of a patient with schizophrenia who was taking antipsychotic medication and was admitted to the emergency room due to the sudden onset of diabetic ketoacidosis (DKA) without any history of diabetes...
February 2024: Psychiatry Investigation
https://read.qxmd.com/read/38431209/psychiatric-and-substance-use-disorders-and-their-association-with-clinical-outcomes-in-diabetic-ketoacidosis-and-hyperosmolar-hyperglycemic-syndrome
#11
JOURNAL ARTICLE
Jacinta Leyden, Amy Uber, Juan P Herrera-Escobar, Nomi C Levy-Carrick
BACKGROUND: Diabetic Ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are life-threatening conditions that send nearly 180,000 patients to the ICU each year, with mortality rates up to 5-10%. Little is known about the impact of concurrent psychiatric disorders on specific DKA/HHS outcomes. Identifying these relationships offers opportunities to improve clinical management, treatment planning, and mitigate associated morbidity and mortality. METHODS: We conducted a retrospective review including adult DKA/HHS admissions within a large Massachusetts hospital system from 2010 - 2019...
February 29, 2024: Journal of the Academy of Consultation—Liaison Psychiatry
https://read.qxmd.com/read/38422833/a-whole-brain-neuromark-resting-state-fmri-analysis-of-first-episode-and-early-psychosis-evidence-of-aberrant-cortical-subcortical-cerebellar-functional-circuitry
#12
JOURNAL ARTICLE
Kyle M Jensen, Vince D Calhoun, Zening Fu, Kun Yang, Andreia V Faria, Koko Ishizuka, Akira Sawa, Pablo Andrés-Camazón, Brian A Coffman, Dylan Seebold, Jessica A Turner, Dean F Salisbury, Armin Iraji
Psychosis (including symptoms of delusions, hallucinations, and disorganized conduct/speech) is a main feature of schizophrenia and is frequently present in other major psychiatric illnesses. Studies in individuals with first-episode (FEP) and early psychosis (EP) have the potential to interpret aberrant connectivity associated with psychosis during a period with minimal influence from medication and other confounds. The current study uses a data-driven whole-brain approach to examine patterns of aberrant functional network connectivity (FNC) in a multi-site dataset comprising resting-state functional magnetic resonance images (rs-fMRI) from 117 individuals with FEP or EP and 130 individuals without a psychiatric disorder, as controls...
February 28, 2024: NeuroImage: Clinical
https://read.qxmd.com/read/38419952/case-report-uncovering-hidden-glucose-patterns-in-medicated-versus-unmedicated-bipolar-disorder-and-comorbid-type-1-diabetes-mellitus
#13
Dagmar Breznoscakova, Maria Pallayova
INTRODUCTION: Type 1 diabetes mellitus is characterized by an absolute insulin deficiency requiring the lifetime intensive insulin therapy accompanied by daily self-monitoring, self-management, ongoing education, and complex diabetes care. Regular patient-clinician shared therapeutic decisions based on age, sex, comorbidities, medications, predicted impact of meals, physical activity, stress, hormonal changes, insulin therapy, and patterns of glycemic changes are key for achieving glycemic targets...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414722/anti-nmda-receptor-encephalitis-and-concurrent-neuroborreliosis-misdiagnosed-for-post-covid-19-syndrome-a-case-report
#14
Tobias Brummer, Johannes Lotz, Christian Dresel, Frank Birklein
We present a case of a 42-year-old woman with paraneoplastic anti-N-Methyl-D-Aspartat (NMDA)-receptor encephalitis and concurrent neuroborreliosis that was initially misdiagnosed as post-COVID-19 syndrome. Clinically, the patient presented with a range of chronic and subacute neuropsychiatric symptoms and recalled a tick bite weeks prior to admission. The patient had undergone psychiatric and complementary medical treatments for 1 year before admission and was initially diagnosed with post-COVID-19 syndrome...
2024: Therapeutic Advances in Neurological Disorders
https://read.qxmd.com/read/38414227/patterns-and-outcomes-of-traumatic-suicides-a-retrospective-study-of-132-patients-admitted-to-a-turkish-medical-center
#15
JOURNAL ARTICLE
Meltem Gürü, Habibe Selmin Özensoy
BACKGROUND Patients who have attempted suicide by traumatic mechanisms and who present to the Emergency Department (ED) are important due to their severity and high mortality. This retrospective study aimed to evaluate the presentation 132 cases of attempted suicide admitted to a hospital ED in Ankara, Turkey, between September 2022 and August 2023. MATERIAL AND METHODS This retrospective study assessed data on 132 adult patients who presented at the ED of Ankara City Hospital due to attempted suicide by traumatic method during a 1-year study period...
February 28, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38398500/neuropsychiatric-systemic-lupus-erythematosus-molecules-involved-in-its-imunopathogenesis-clinical-features-and-treatment
#16
REVIEW
Angel A Justiz-Vaillant, Darren Gopaul, Sachin Soodeen, Rodolfo Arozarena-Fundora, Odette Arozarena Barbosa, Chandrashehkar Unakal, Reinand Thompson, Bijay Pandit, Srikanth Umakanthan, Patrick E Akpaka
Systemic lupus erythematosus (SLE) is an idiopathic chronic autoimmune disease that can affect any organ in the body, including the neurological system. Multiple factors, such as environmental (infections), genetic (many HLA alleles including DR2 and DR3, and genes including C4), and immunological influences on self-antigens, such as nuclear antigens, lead to the formation of multiple autoantibodies that cause deleterious damage to bodily tissues and organs. The production of autoantibodies, such as anti-dsDNA, anti-SS(A), anti-SS(B), anti-Smith, and anti-neuronal DNA are characteristic features of this disease...
February 6, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38397620/impaired-well-being-and-insomnia-as-residuals-of-resolved-medical-conditions-survey-in-the-italian-population
#17
JOURNAL ARTICLE
Danilo Menicucci, Luca Bastiani, Eleonora Malloggi, Francesca Denoth, Angelo Gemignani, Sabrina Molinaro
BACKGROUND: Well-being encompasses physical, mental, social, and cultural aspects. Sleep quality and pathologies are among the objective conditions jeopardising it. Chronic insomnia, inflammatory-based diseases, and mood disorders often occur in a single cluster, and inflammation can negatively impact sleep, potentially harming well-being. Some evidence from specific clinical populations suggests that also some resolved past diseases could still have an impact on present sleep quality and well-being...
January 24, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38397100/autism-spectrum-disorder-brain-areas-involved-neurobiological-mechanisms-diagnoses-and-therapies
#18
REVIEW
Jacopo Lamanna, Jacopo Meldolesi
Autism spectrum disorder (ASD), affecting over 2% of the pre-school children population, includes an important fraction of the conditions accounting for the heterogeneity of autism. The disease was discovered 75 years ago, and the present review, based on critical evaluations of the recognized ASD studies from the beginning of 1990, has been further developed by the comparative analyses of the research and clinical reports, which have grown progressively in recent years up to late 2023. The tools necessary for the identification of the ASD disease and its related clinical pathologies are genetic and epigenetic mutations affected by the specific interaction with transcription factors and chromatin remodeling processes occurring within specific complexes of brain neurons...
February 19, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38389341/applications-of-pet-and-spect-in-patients-with-autism-spectrum-disorder
#19
JOURNAL ARTICLE
Anna Lisa Martini, Natale Quartuccio, Irene Giovanna Schiera, Valentina Berti, Luca Burroni, Angelina Cistaro
Autism spectrum disorder (ASD) consists of neurological development disorders that manifest before three years of age and affect social interactions, markedly restricting range of interests and activities, often associated with some degree of intellectual disability. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are non-invasive imaging tools to investigate the function of the brain in vivo. SPECT and PET studies exploring rCBF and brain glucose metabolism in patients with ASD have been performed, providing important insights into the brain regions involved in ASD...
2024: Current medical imaging
https://read.qxmd.com/read/38387837/an-evolutionary-analysis-of-the-applicability-and-utility-of-the-clinico-pathological-method-in-psychiatry
#20
REVIEW
Alfonso Troisi
Unlike other medical specialties, psychiatry has not been involved in the theoretical shift that replaced the syndromal approach with the clinico-pathological method, which consists in explaining clinical manifestations by reference to morbid anatomical and physiological changes. Past and present discussions on the applicability of the clinico-pathological method in psychiatry are based on a pre-Darwinian concept of biology as the study of proximate causation. Distinguishing between mediating mechanisms and evolved functions, an evolutionary perspective offers an original contribution to the debate by overcoming the opposite views of dualism (i...
February 20, 2024: Neuroscience and Biobehavioral Reviews
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