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https://www.readbyqxmd.com/read/29220543/skin-cancer-prevention-campaign-in-childhood-survey-based-on-3-676-children-in-brazil
#1
Paulo Ricardo Criado, Jorge Ocampo-Garza, Anne Lise Dias, Walter Belda Junior, Nilton Di Chiachio, Aparecida Machado de Moraes, Meire Brasil Parada, Fátima de Oliveira Rabay, Octavio Moraes Junior, Renato Sau Rios, Cristiana Silveira da Silva, Francisco C S Ferreira, Samuel Henrique Mandeulbaum, Cidia Vasconcellos
BACKGROUND AND OBJECTIVES: Primary skin cancer prevention campaigns are essential and more effective among children, not only because of the importance of sun exposure effects during this period, but also because at this age is when individuals are developing behaviors. The Brazilian Society of Dermatology - Regional State of Sao Paulo developed and conducted, the program named "The Sun, Friend of Childhood", a school health education and disease prevention project for children and parents...
December 8, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29215650/phenocopies-in-melanoma-prone-families-with-germ-line-cdkn2a-mutations
#2
Hildur Helgadottir, Håkan Olsson, Margaret A Tucker, Xiaohong R Yang, Veronica Höiom, Alisa M Goldstein
PurposeCarriers of CDKN2A mutations have high risks of melanoma and certain other cancers. In this study we examined the occurrence of tumors among CDKN2A wild type (wt) members of melanoma-prone families with CDKN2A mutations.MethodsSwedish and US melanoma-prone families with CDKN2A mutations were included. Data was collected on tumors diagnosed among family members. Among the CDKN2A mutated families, members with CDKN2A wt status who were diagnosed with melanoma were designated phenocopies.ResultsOf patients with melanoma in the CDKN2A mutated families (n = 266), 7...
December 7, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29204388/clinic-based-group-multi-professional-education-causes-significant-decline-in-psoriasis-severity-a-randomized-open-label-pilot-study
#3
Shubh Mohan Singh, Tarun Narang, Keshavamurthy Vinay, Aditi Sharma, Ashirbad Satapathy, Sanjeev Handa, Sunil Dogra
Background: The evidence for efficacy of psychoeducational interventions in psoriasis is not well researched. Objective: The objective of this study was to assess the benefits of a group, multi-professional, psychoeducational training in psoriasis. Materials and Methods: Adults with moderate-to-severe psoriasis were randomized into psychoeducational intervention plus treatment (intervention arm [IA]) and treatment as usual alone (control arm [CA]) groups using random number tables...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29197467/diagnostic-tools-to-use-when-we-suspect-an-allergic-reaction-to-a-tattoo-a-proposal-based-on-cases-at-our-hospital
#4
I González-Villanueva, J F Silvestre Salvador
INTRODUCTION: Tattooing has become a popular practice in western countries, particularly among younger populations. Tattoos, however, can cause complications, such as infections, allergic or foreign-body reactions, and even systemic inflammatory responses. PATIENTS AND METHODS: We conducted a retrospective study of all patients seen for tattoo-related complications at our skin allergy unit between January 2002 and December 2016. RESULTS: We studied 23 patients...
November 29, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29188286/association-of-dermatologist-density-with-the-volume-and-costs-of-dermatology-procedures-among-medicare-beneficiaries
#5
Sally Y Tan, Daphne Tsoucas, Arash Mostaghimi
Importance: The persistent shortage of dermatologists in the United States affects access to care and patient outcomes. Objective: To characterize the effect of geographic variations in dermatologist density on the provision of dermatology procedures within Medicare. Design, Setting, and Participants: This was a cross-sectional study using the 2013 Medicare Provider Utilization and Payment Database. Dermatology-related procedures were defined by the top 50 billing codes accounting for more than 95% of procedures billed by dermatologists...
November 29, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29142034/cumulative-burden-of-glucocorticoid-related-adverse-events-in-patients-with-systemic-lupus-erythematosus-findings-from-a-12-year-longitudinal-study
#6
Hung-Lin Chen, Li-Jiuan Shen, Ping-Ning Hsu, Chieh-Yu Shen, Susan A Hall, Fei-Yuan Hsiao
OBJECTIVE: The aim of this population-based study is to examine the adverse events (AE) associated with longitudinal systemic glucocorticoid (GC) use among an ethnic Chinese systemic lupus erythematosus (SLE) cohort. METHODS: Our study subjects were patients with newly diagnosed SLE aged 18 and older who received at least 1 prescription of systemic GC between 2001 and 2012 from Taiwan's National Health Insurance Research Database (NHIRD). The earliest prescription date of systemic GC for each subject was defined as the index date...
November 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29116441/validation-of-the-toronto-psoriatic-arthritis-screen-ii-topas-ii-questionnaire-in-a-turkish-population
#7
Mehmet Tuncay Duruöz, Canan Şanal Toprak, Fırat Ulutatar
OBJECTIVE: To evaluate the TOPAS II questionnaire validation in a Turkish population. METHODS: The Turkish translation of ToPAS II was sent to us by the developer authors of the original index. Subjects were recruited from dermatology, physical medicine and rehabilitation, and rheumatology outpatient clinics. All patients' demographic parameters and ToPAS II questionnaire results were recorded. After patients completed the questionnaire they were assessed by a rheumatologist according to a standard protocol which includes a complete history, detailed physical examination, laboratory tests and CASPAR criteria...
November 7, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29102368/-body-dysmorphic-disorder-future-prospects-of-medical-care
#8
E Siegfried, A Ayrolles, H Rahioui
Body dysmorphic disorder (BDD) is characterized by excessive preoccupation with a slight or imagined defect in one's physical appearance, believing they look ugly, abnormal or deformed. While the most common preoccupations focus on the skin, hair and nose, any part of the body may be involved. Preoccupations are intrusive, time-consuming and hard to control. Repetitive behaviors are performed in response to the preoccupations. BDD is associated with marked impairment in socio-professional functioning, poor quality of life and high suicide rates...
November 1, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29061762/descriptive-analysis-of-the-medical-care-performed-in-the-spanish-military-role-1-medical-treatment-facility-deployed-in-operation-inherent-resolve-iraq-2015-2016
#9
Rafael García Cañas, R Navarro Suay
INTRODUCTION: Operation 'Inherent Resolve' was approved by the United Nations in August 2014 with the objective of suppressing the Islamic State in Iraq and the Levant and increasing the region's stability. The mission of the Spanish military forces within this was to direct training missions for the Iraqi Army. The aim of this study is to analyse the medical care provided in the Spanish Role 1 deployed medical treatment facility during Operation 'Apoyo a Irak'. METHODS: A cross-sectional, descriptive and retrospective study was conducted between 15 December 2015 and 18 November 2016...
October 23, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29054605/increased-prevalence-of-filaggrin-deficiency-in-51-patients-with-recessive-x-linked-ichthyosis-presenting-for-dermatological-examination
#10
Kira Süßmuth, Robert Gruber, Elke Rodriguez, Heiko Traupe, Susanne Amler, Alberto Sánchez-Guijo, Frederic Valentin, Tatjana Tarinski, Natalia Straub, Dieter Metze, Stefan W Schneider, Ingrid Hausser, Hansjörg Baurecht, Stephan Weidinger, Vinzenz Oji
X-linked ichthyosis (XLI) is a keratinization disorder caused by deficient activity of steroidsulfatase. In contrast, ichthyosis vulgaris is due to semidominant mutations of the filaggrin gene (FLG). In view of phenotypic variations of these ichthyoses we speculated that XLI may be influenced by additional FLG mutations in a significant number of patients. We characterized a group of 51 patients with XLI and systematically analyzed them for additional FLG mutations (R501X, 2282del4, R2447X, S3247X). The study was complemented by morphological analyses...
October 17, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29048751/severity-strata-for-five-patient-reported-outcomes-in-adults-with-atopic-dermatitis
#11
P P Vakharia, R Chopra, R Sacotte, N Patel, S Immaneni, T White, R Kantor, D Y Hsu, E L Simpson, J I Silverberg
BACKGROUND: Multiple patient-reported outcomes have been used to assess the burden of atopic dermatitis (AD). Some are disease specific, e.g. the Patient Oriented Eczema Measure (POEM). While others pertain to itch, e.g. Numerical Rating Scale (NRS)-itch, ItchyQoL and 5-D itch, or dermatologic disease in general, e.g. Dermatology Life Quality Index (DLQI). Development of severity strata is essential for proper interpretability of these assessments. We sought to confirm previously developed strata for POEM, DLQI and raw ItchyQoL, and develop strata for the NRS-itch, mean ItchyQOL and 5-D itch scale for use in adults with AD...
October 19, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29030263/the-role-of-endemic-plants-in-mauritian-traditional-medicine-potential-therapeutic-benefits-or-placebo-effect
#12
REVIEW
Nawraj Rummun, Vidushi S Neergheen-Bhujun, Kersley B Pynee, Cláudia Baider, Theeshan Bahorun
ETHNOPHARMACOLOGICAL RELEVANCE: The Mauritian endemic flora has been recorded to be used as medicines for nearly 300 years. Despite acceptance of these endemic plants among the local population, proper documentation of their therapeutic uses is scarce. This review aims at summarising documented traditional uses of Mauritian endemic species with existing scientific data of their alleged bioactivities, in a view to appeal for more stringent validations for their ethnomedicinal uses. MATERIAL AND METHODS: A comprehensive bibliographic investigation was carried out by analysing published books on ethnopharmacology and international peer-reviewed papers via scientific databases namely ScienceDirect and PubMed...
October 10, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29020350/monitoring-of-parasite-kinetics-in-indian-post-kala-azar-dermal-leishmaniasis
#13
Srija Moulik, Surya Jyati Chaudhuri, Bikash Sardar, Manab Ghosh, Bibhuti Saha, Nilay Kanti Das, Mitali Chatterjee
Background: The potential reservoirs of Leishmaniasis in South Asia include relapsed cases of visceral leishmaniasis, patients with Post-Kala-azar dermal leishmaniasis (PKDL) and an asymptomatically infected population. Therefore, assessment of cure in terms of parasite clearance, early detection of PKDL and asymptomatic VL are pivotal for ensuring elimination. This study aimed to monitor the efficacy of Miltefosine and Liposomal Amphotericin B (LAmB) in PKDL based on parasite load. Methods: Patients with PKDL were recruited from the Dermatology outpatient departments or during active field surveys...
September 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28989106/demographic-and-healthcare-service-utilization-by-4-417-patients-with-hidradenitis-suppurativa
#14
Guy Shalom, Meir Babaev, Tamar Freud, Shmuel Tiosano, Nadav Pam, Amir Horev, Jacob Dreiher, Daniel A Vardy, Doron Comaneshter, Arnon D Cohen
BACKGROUND: Data on the healthcare utilization of hidradenitis suppurativa (HS) patients in primary care settings are scarce. OBJECTIVE: To investigate the healthcare service utilization of patients with HS. PATIENTS AND METHODS: In a cross-sectional study, HS patients were compared with two age- and gender-matched control groups-general population enrollees of Clalit Health Services and a group of patients with psoriasis. Healthcare services data included inpatient and outpatient community clinic visits and pharmacy claims for topical and systemic treatments...
October 5, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28954266/low-utilization-of-the-dermatology-ambulatory-encounter-among-patients-with-hidradenitis-suppurativa-a-population-based-retrospective-cohort-analysis-in-the-usa
#15
Amit Garg, Jonathan Lavian, Andrew Strunk
BACKGROUND: There are limited data evaluating the utilization of dermatologists for the care of patients with hidradenitis suppurativa. OBJECTIVE: To determine the utilization of the dermatology ambulatory encounter among hidradenitis suppurativa patients, and to evaluate whether utilization varies by insurance status. METHODS: This was a retrospective cohort analysis in an adult population sample of 42,030 hidradenitis suppurativa patients with either private or public health insurance who were identified by a validated scheme using SNOMED-CT terminology...
September 28, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28944414/the-spectrum-of-skin-biopsies-and-excisions-in-a-pediatric-skin-center
#16
Martin Theiler, Kathrin Neuhaus, Katrin Kerl, Lisa Weibel
Little is known about the spectrum of pediatric skin disorders requiring biopsy/excision, their indication, impact on further management, and the accuracy of clinical diagnosis. We aimed to address these questions in the patient population seen at our Swiss University referral center for Pediatric Dermatology and Plastic Surgery. All skin biopsies/excisions performed in patients aged ≤ 16 years over a period of 2 years were retrospectively analyzed. A total of 506 samples were included. The majority of biopsies/excisions (n = 413, 82%) was performed for tumors, cysts, and hamartomas and 18% for other skin conditions...
December 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28920474/the-state-of-ethnic-dermatology-in-canada
#17
Boluwaji Ogunyemi, Yvette Miller-Monthrope
Approximately 30% of Canadians will be members of a visible minority by 2031. When dermatology became an independent medical discipline in the late 18th and early 19th centuries, most residents of Canada and the United States were of Northern European descent. Morphology and descriptions of dermatoses are based on patients with light skin. Skin of colour dermatology refers to a unique field in dermatology dedicated to the diagnosis and management of disorders that are more prevalent in patients with moderately to richly pigmented skin...
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28912966/abcc6-gene-analysis-in-20-japanese-patients-with-angioid-streaks-revealing-four-frequent-and-two-novel-variants-and-pseudodominant-inheritance
#18
Satoshi Katagiri, Yuya Negishi, Kei Mizobuchi, Mitsuyoshi Urashima, Tadashi Nakano, Takaaki Hayashi
PURPOSE: To report the spectrum of ABCC6 variants in Japanese patients with angioid streaks (AS). PATIENTS AND METHODS: This was a single-center cohort study. The medical records of 20 patients with AS from 18 unrelated Japanese families were retrospectively reviewed. Screening of the ABCC6 gene (exons 1 to 31) was performed using PCR-based Sanger sequencing. RESULTS: Eight ABCC6 variants were identified as candidate disease-causing variants...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28902286/specific-antigen-serologic-tests-in-leprosy-implications-for-epidemiological-surveillance-of-leprosy-cases-and-household-contacts
#19
Ana Paula Mendes Carvalho, Angélica da Conceição Oliveira Coelho, Rodrigo Correa-Oliveira, Francisco Carlos Félix Lana
BACKGROUND: There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE: The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disaccharide linked to human serum albumin via an octyl (NDOHSA), a semisynthetic phenolic glycolipid-I (PGL-I); Leprosy Infectious Disease Research Institute Diagnostic-1 (LID-1) and natural disaccharide octyl - Leprosy Infectious Disease Research Institute Diagnostic-1 (NDOLID)...
September 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28879584/adverse-event-profile-of-pyrimethamine-based-therapy-in-toxoplasmosis-a-systematic-review
#20
REVIEW
Ruben R Ben-Harari, Elizabeth Goodwin, Julio Casoy
INTRODUCTION: Approximately a third of the population worldwide is chronically infected with Toxoplasma gondii. Pyrimethamine-based regimens are recommended for the treatment of toxoplasmosis. OBJECTIVE: The aim was to evaluate the safety profile of pyrimethamine-based treatment for the three main Toxoplasma manifestations: toxoplasmic encephalitis (TE), ocular toxoplasmosis, and congenital toxoplasmosis. METHODS: PubMed, Cochrane Library, and Google Scholar databases were searched through August 1, 2016...
December 2017: Drugs in R&D
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