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https://www.readbyqxmd.com/read/27879085/potential-drug-drug-interactions-and-adverse-drug-reactions-in-dermatological-inpatients
#1
Lukas Koch, Birger Kränke, Werner Aberer
OBJECTIVES: To present information on the frequency of drug-drug interactions and adverse drug reactions, and to provide assistance on how to minimize these major problems in the pharmacological treatment of dermatological inpatients. PATIENTS AND METHODS: The medications given to 1,099 dermatological inpatients were retrospectively analyzed for drug-drug interactions and adverse drug reactions using web-based drug interaction software (Diagnosia(®) Check). RESULTS: We report an overall frequency of relevant drug-drug interactions of 51...
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27878058/patient-factors-and-their-association-with-nonmelanoma-skin-cancer-morbidity-and-the-performance-of-self-skin-exams-a-cross-sectional-study
#2
Kyle T Amber, Romi Bloom, Mohammad-Ali Yazdani Abyaneh, Leyre A Falto-Aizpurua, Martha Viera, Martin N Zaiac, Keyvan Nouri, Shasa Hu
Objective: Mohs micrographic surgery is widely utilized for the treatment of nonmelanoma skin cancers with the advantage of tissue sparing and higher cure rate. The preoperative tumor size and post-Mohs micrographic surgery defect size are useful surrogate measures of nonmelanoma skin cancer morbidity. The authors sought to evaluate whether gender, Hispanic ethnicity, socioeconomic status, sun-safe practices and self-skin exams affected tumor size and Mohs micrographic surgery defect size. They also investigated factors associated with self-skin exams...
September 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/27874213/questioning-the-clinical-utility-of-exome-sequencing-in-developing-countries
#3
Kenneth Fong, Celeste V Bailey, Peggy Tuttle, Bari Cunningham, John A McGrath, Raymond J Cho
The availability of whole-exome sequencing has revolutionized the study of genetic disease in recent years, particularly in dermatology, where clinical phenotypes are readily recognized. As this technology becomes increasingly affordable and accessible, questions are emerging regarding the clinical and ethical responsibilities of physicians who determine variants underlying disease, especially with regard to children, for whom treatment may be warranted and clinical course improved based on a known genotype...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27837412/skin-bleaching-and-dermatologic-health-of-african-and-afro-caribbean-populations-in-the-us-new-directions-for-methodologically-rigorous-multidisciplinary-and-culturally-sensitive-research
#4
Emma K T Benn, Andrew Alexis, Nihal Mohamed, Yan-Hong Wang, Ikhlas A Khan, Bian Liu
Skin-bleaching practices, such as using skin creams and soaps to achieve a lighter skin tone, are common throughout the world and are triggered by cosmetic reasons that oftentimes have deep historical, economic, sociocultural, and psychosocial roots. Exposure to chemicals in the bleaching products, notably, mercury (Hg), hydroquinone, and steroids, has been associated with a variety of adverse health effects, such as Hg poisoning and exogenous ochronosis. In New York City (NYC), skin care product use has been identified as an important route of Hg exposure, especially among Caribbean-born blacks and Dominicans...
November 11, 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27785785/epidemiological-trends-and-clinicopathological-features-of-cutaneous-melanoma-in-sporadic-and-xeroderma-pigmentosum-tunisian-patients
#5
Chokri Naouali, Meriem Jones, Imen Nabouli, Manel Jerbi, Haifa Tounsi, Mariem Ben Rekaya, Melika Ben Ahmed, Balkiss Bouhaouala, Olfa Messaoud, Aida Khaled, Mohamed Zghal, Sonia Abdelhak, Samir Boubaker, Houda Yacoub-Youssef
BACKGROUND: Epidemiological features and trends of cutaneous melanoma (CM) in North-African populations remain unclear. Those populations are of particular interest as they belong to a mosaic of various other origins (sub-Saharan, European Ancestry, and North-African Berbers). The aim of this study is to draw epidemiological profile and clinicopathological features of CM in the Tunisian population. METHODS: Incidence analyses were based on data from regional cancer registries...
October 26, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27784045/association-between-method-of-prescribing-and-primary-nonadherence-to-dermatologic-medication-in-an-urban-hospital-population
#6
Adewole S Adamson, Elizabeth A Suarez, April R Gorman
Importance: Prescription underuse is associated with poorer clinical outcomes. A significant proportion of underuse is owing to primary nonadherence, defined as the rate at which patients fail to fill and pick up new prescriptions. Although electronic prescribing increases coordination of care and decreases errors, its effect on primary nonadherence is less certain. Objectives: To analyze factors associated with primary nonadherence to dermatologic medications and study whether electronic prescribing affects rates of primary nonadherence...
October 26, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27782026/a-review-and-critique-of-teledermatology-in-the-south-african-public-health-sector
#7
Laticha E M Walters, Maurice Mars, Richard E Scott
: Nearly 80% of the world's population live in developing countries in Asia, Africa, and Latin America. Many of these countries must face a triple or quadruple burden of disease with severely limited resources and health systems. South Africa (SA) is one such country, and recognises the potential for e-health to moderate these limitations. Dermatological issues remain a concern in SA and globally. Indeed, the World Health Organisation (WHO) has recognised that a number of diseases are most likely to manifest themselves through a dermatological problem before becoming full-blown...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27761610/avoiding-psychological-pitfalls-in-aesthetic-medical-procedures
#8
Qiuyu Wang, Chuan Cao, Rui Guo, Xiaoge Li, Lele Lu, Wenping Wang, Shirong Li
OBJECTIVE: To assess the prevalence of body dysmorphic disorder (BDD) in an aesthetic surgery setting in the region of Southwest China, and to ascertain the differences in terms of body images between patients in the aesthetic setting and general Chinese population. This study tracked patient satisfaction with their body image changes while undergoing aesthetic medical procedures to identify whether the condition of patients who were presenting with BDD symptoms or their psychological symptoms could be improved by enhancing their appearance...
December 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27756084/-network-analyses-in-regional-health-care-research-example-of-dermatological-care-in-the-metropolitan-region-of-hamburg
#9
J Augustin, J Austermann, S Erasmi
Background: One of the overall objectives of the legislator is to ensure an overall "homogeneous", and easily accessible medical care for the population. The physician-patient ratio can be used to describe the regional health care situation. But this method does not provide information concerning the availability of, for instance, the nearest doctor. Therefore, further parameters such as accessibility must be taken into consideration. For this purpose, network analyses are an appropriate method. The objective of this study is to present methodological tools to evaluate the healthcare situation in the metropolitan region of Hamburg, primarily focusing on accessibility using dermatologists as an example...
October 18, 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27731355/quantification-and-characterization-of-uvb-induced-mitochondrial-fragmentation-in-normal-primary-human-keratinocytes
#10
Romain Jugé, Josselin Breugnot, Célia Da Silva, Sylvie Bordes, Brigitte Closs, Abdel Aouacheria
UV irradiation is a major environmental factor causing skin dryness, aging and cancer. UVB in particular triggers cumulative DNA damage, oxidative stress and mitochondrial dysfunction. The objective of our study was to provide both qualitative and quantitative analysis of how mitochondria respond to UVB irradiation in normal human epidermal keratinocytes (NHEK) of healthy donors, with the rationale that monitoring mitochondrial shape will give an indication of cell population fitness and enable the screening of bioactive agents with UVB-protective properties...
October 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27695866/evaluation-of-hygiene-habits-cross-sectional-study
#11
Manuel António Campos, Ana Cristina Sousa, Paulo Varela, Armando Baptista
Introduction: It is well known that adequate hygiene is important for health. Even though this topic has drawn the attention of the media, little or no scientific investigation has been done. Methods: We performed a comparative questionnaire-based cross-sectional study in three groups: patients attending a dermatology outpatient clinic, patients attending an internal medicine consultation, and community members. Results: We analyzed a total of 446 questionnaires (249 from dermatology patients, 98 from internal medicine patients, and 99 from the community group)...
September 2016: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/27694303/validation-of-a-screening-questionnaire-for-chronic-leg-ulcers
#12
Kian Zarchi, Peter Theut Riis, Christine Graversgaard, Iben M Miller, Michael Heidenheim, Gregor B E Jemec
The use of a validated screening questionnaire to identify individuals with chronic leg ulcers allows large-scale population-based studies to be conducted that measure and monitor the prevalence of the disease. The aim of this study was to design and validate such a screening questionnaire to identify patients with chronic leg ulcers. A simple 3-item questionnaire was developed at the Department of Dermatology, University Hospital of Zealand, Denmark. In total, 90 patients attending the department's outpatient clinic for dermatological diseases and chronic wounds were included in this study...
September 29, 2016: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/27689254/doctors-recognition-and-management-of-melanoma-patients-risk-an-australian-population-based-study
#13
C M Madronio, B K Armstrong, C G Watts, C Goumas, R L Morton, A Curtin, S W Menzies, G J Mann, J F Thompson, A E Cust
BACKGROUND: Guidelines recommend that health professionals identify and manage individuals at high risk of developing melanoma, but there is limited population-based evidence demonstrating real-world practices. OBJECTIVE: A population-based, observational study was conducted in the state of New South Wales, Australia to determine doctors' knowledge of melanoma patients' risk and to identify factors associated with better identification and clinical management. METHODS: Data were analysed for 1889 patients with invasive, localised melanoma in the Melanoma Patterns of Care study...
December 2016: Cancer Epidemiology
https://www.readbyqxmd.com/read/27681739/botulinum-toxin-a-for-controlling-obesity
#14
Raffaela Pero, Lorena Coretti, Francesca Lembo
Rapid growth of the overweight population and the number of obese individuals in recent decades suggests that current strategies based on diet, exercise, and pharmacological knowledge are not sufficient to address this epidemic. Obesity is the result of a high caloric intake and energy storage, not counterbalanced by an equally important energy expense. Botulinum toxin type A (BoNT-A) use is rapidly expanding to include treatment of a variety of ophthalmological, gastrointestinal, urological, orthopedic, dermatological, secretory, painful, and cosmetic disorders...
2016: Toxins
https://www.readbyqxmd.com/read/27680009/-cutaneous-squamous-cell-carcinoma
#15
U Leiter, R Gutzmer, M Alter, C Ulrich, A S Lonsdorf, M M Sachse, U Hillen
Squamous cell carcinoma (SCC) of the skin accounts for 20 % of non-melanoma skin cancer and is one of the most frequent types of cancer in Caucasian populations. Diagnosis is based on the clinical features and should be histopathologically confirmed to adequately address the prognosis and treatment. Complete surgical excision with histopathological control of excision margins is the gold standard in the treatment of primary SCC. Sentinel lymph node biopsies (SLNB) can be considered in SCC with a tumor thickness of >6 mm but there is currently no evidence concerning prognostic and therapeutic effects...
September 28, 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27663926/tinea-on-a-tattoo
#16
Alexandru Oanţă, Marius Irimie
In the last twenty years, the prevalence of individuals with tattoos in the general population has increased in Europe (1) as well as in Australia (2) and the United States of America (3). A series of complications such as acute inflammatory reactions, allergic contact dermatitis (4,5), photoinduced, lichenoid, and granulomatous reactions (6, 7), pseudolymphoma (8), pseudoepitheliomatous hyperplasia (9), skin infections (6), and skin cancers (10) may occur on tattoos. Infectious complications on tattoos include bacterial infections (pyoderma, leprosy, syphilis, cutaneous tuberculosis, mycobacteriosis) (11-14), viral infections (molluscum contagiosum, warts, herpes simplex, hepatitis B and C) (15-17), and fungal infections (sporotrichosis, dermatophytosis) (18,19)...
August 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27649398/what-is-the-standard-of-treatment-for-plantar-psoriasis
#17
Thomas B Birdwell, Sadiah M Hoque, Mara C Kennedy, Jane H Sim, Tracey C Vlahovic
INTRODUCTION AND OBJECTIVES: Psoriasis is a systemic condition with several dermatological manifestations that affect many individuals on a daily basis. According to Langley et al in a study titled "Psoriasis: epidemiology, clinical features, and quality of life," psoriasis affects 2% of the American population, which is approximately 6 million people. Out of these 6 million people, approximately 2-3% are affected by palmoplantar psoriasis (Farber et al). Plantar psoriasis in particular can cause significant functional and social disabilities...
September 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27647359/cutaneous-problems-in-elderly-diabetics-a-population-based-comparative-cross-sectional-survey
#18
N Asokan, V G Binesh
BACKGROUND: There are few population-based studies on prevalence of cutaneous problems in diabetes mellitus. AIMS: To identify skin problems associated with diabetes mellitus among elderly persons in a village in Kerala. METHODS: In this population-based cross-sectional survey, we compared the prevalence of skin problems among 287 elderly diabetics (aged 65 years or more) with 275 randomly selected elderly persons without diabetes mellitus...
September 20, 2016: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/27638444/phototherapy-in-children-considerations-and-indications
#19
Cary S Crall, Jillian F Rork, Sophia Delano, Jennifer T Huang
Phototherapy can be a safe and effective treatment for various skin diseases in children. Special considerations governing the use of this treatment modality in pediatric populations include patient, family, and facility-based factors that are oriented around heightened concerns with regard to safety and tolerability of treatment. Although phototherapy has been found to be effective in a wide range of dermatologic conditions affecting pediatric populations, including psoriasis, atopic dermatitis, pityriasis lichenoides, cutaneous T-cell lymphoma, and vitiligo, there is need for additional research on other conditions in which phototherapy has shown promise...
September 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27623553/experimental-metagenomics-and-ribosomal-profiling-of-the-human-skin-microbiome
#20
Pamela Ferretti, Stefania Farina, Mario Cristofolini, Giampiero Girolomoni, Adrian Tett, Nicola Segata
The skin is the largest organ in the human body and it is populated by a large diversity of microbes, most of which are co-evolved with the host and live in symbiotic harmony. There is increasing evidence that the skin microbiome plays a crucial role in the defence against pathogens, immune system training and homeostasis, and microbiome perturbations have been associated with pathological skin conditions. Studying the skin resident microbial community is thus essential to better understand the microbiome-host crosstalk and to associate its specific configurations with cutaneous diseases...
September 13, 2016: Experimental Dermatology
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