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https://www.readbyqxmd.com/read/29791813/higher-lung-cancer-incidence-in-young-women-than-young-men-in-the-united-states
#1
Ahmedin Jemal, Kimberly D Miller, Jiemin Ma, Rebecca L Siegel, Stacey A Fedewa, Farhad Islami, Susan S Devesa, Michael J Thun
BACKGROUND: Previous studies showed a higher incidence of lung cancer among young women than among young men in the United States. Whether this pattern has continued in contemporary birth cohorts and, if so, whether it can be fully explained by sex differences in smoking behaviors are unknown. METHODS: We examined the nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group (30 to 34, 35 to 39, 40 to 44, 45 to 49, and 50 to 54 years), year of birth (1945 to 1980), and calendar period of diagnosis (1995-1999, 2000-2004, 2005-2009, and 2010-2014), and we calculated female-to-male incidence rate ratios...
May 24, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29791721/persistence-of-treatment-with-biologics-for-patients-with-psoriasis-a-real-world-analysis-of-16-545-biologic-na%C3%A3-ve-patients-from-the-french-national-health-insurance-database-sniiram
#2
E Sbidian, M Mezzarobba, A Weill, J Coste, J Rudant
BACKGROUND: Long-term clinical effectiveness of biologics in psoriasis is needed. OBJECTIVES: We aimed to assess the long-term persistence of biologics used to treat psoriasis in a real-life setting. METHODS: All adults with psoriasis having been registered in the French national health insurance database (SNIIRAM) between 2008 and 2016 were eligible for inclusion. Psoriasis was defined as the fulfilment of at least two prescriptions for topical formulations of vitamin D derivative within a two-year period...
May 23, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29791197/gender-differences-in-psychosocial-determinants-of-self-perceived-health-among-portuguese-older-adults-in-nursing-homes
#3
Violeta Alarcão, Teresa Madeira, Catarina Peixoto-Plácido, Nuno Sousa-Santos, Elisabete Fernandes, Paulo Nicola, Osvaldo Santos, João Gorjão-Clara
OBJECTIVES: Self-perceived health declines with age, varies by gender and is a predictor of mortality, morbidity, physical and psychological functioning. However, gender differences in health and illness perception are complex and not yet fully understood. This study aimed to explore gender-related differences in psychosocial determinants of self-perceived health among older adults living in nursing homes. METHOD: Nationwide face-to-face survey of the Portuguese population aged 65 and over...
May 23, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29790779/the-two-by-four-appliance-a-nationwide-cross-sectional-survey
#4
V Quinzi, R Ferro, F A Rizzo, E M Marranzini, F Federici Canova, S Mummolo, A Mattei, G Marzo
AIM: The aim of the study was to investigate how widespread is the use of the 2 x 4 appliance among Italian general dentists and specialists in orthodontics, as well as the type of treatment employed and length of use. MATERIALS AND METHODS: We conducted a nationwide cross-sectional survey from July 14, 2016 to January 12, 2017 using an online questionnaire of 8 multiple choice questions, created by the SurveyMonkey® Company, on a population of Italian dentists and specialists in orthodontics affiliated with the Italian Society of Paediatric Dentistry (SIOI)...
June 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29790303/association-between-reappearance-of-myeloperoxidase-antineutrophil-cytoplasmic-antibody-and-relapse-in-antineutrophil-cytoplasmic-antibody-associated-vasculitis-subgroup-analysis-of-nationwide-prospective-cohort-studies
#5
Haruki Watanabe, Ken-Ei Sada, Yoshinori Matsumoto, Masayoshi Harigai, Koichi Amano, Hiroaki Dobashi, Shouichi Fujimoto, Joichi Usui, Kunihiro Yamagata, Tatsuya Atsumi, Shogo Banno, Takahiko Sugihara, Yoshihiro Arimura, Seiichi Matsuo, Hirofumi Makino
OBJECTIVE: The aim of this study was to evaluate clinical links between levels of myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA) and relapse in patients with ANCA-associated vasculitis (AAV) using a data set from two nationwide prospective cohort studies. METHODS: From the cohort studies, 477 MPO-ANCA positive patients, who achieved remission during the 6 months after remission induction therapy, were enrolled. We measured MPO-ANCA levels at months 0, 3, 6, 12, 18, 24, and at the time of relapse...
May 22, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29790022/compliance-with-pregnancy-prevention-recommendations-for-isotretinoin-in-estonia-in-2012-2016
#6
Anneli Uusküla, Heti Pisarev, Katrin Kurvits, Ott Laius, Made Laanpere, Maia Uusküla
BACKGROUND: Isotretinoin is an effective treatment for severe acne; no alternative treatment has an equal therapeutic effect. The teratogenic effects of isotretinoin can be avoided, and numerous recommendations and regulations are in force to minimize the risk of pregnancy during treatment. OBJECTIVES: To describe isotretinoin prescription patterns for women aged 15-45 years, assess the concomitancy of isotretinoin and contraceptive use, and determine the rate of potential isotretinoin-exposed pregnancies in Estonia...
May 22, 2018: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29789871/emergency-admissions-for-complicated-colonic-diverticulitis-are-increasing-a-nationwide-register-based-cohort-study
#7
Line Hupfeld, Hans-Christian Pommergaard, Jakob Burcharth, Jacob Rosenberg
BACKGROUND: Acute colonic diverticulitis is common in the Western world representing a growing burden on health care. We aimed to report the factual epidemiological and demographic characteristics in patients with acute diverticulitis in a large nationwide population. METHOD: We conducted a population-based cohort study from 2000 to 2012 on the complete Danish population, which included all patients with acute colonic diverticulitis. Data were composed through two national longitudinal registries...
May 22, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29789444/short-term-seizure-outcomes-in-childhood-epilepsy
#8
Kari Modalsli Aaberg, Inger Johanne Bakken, Morten I Lossius, Camilla Lund Søraas, Kamath K Tallur, Camilla Stoltenberg, Richard Chin, Pål Surén
BACKGROUND AND OBJECTIVES: Seizure freedom is the optimal response to antiepileptic treatment. In previous studies, it has been shown that between 61% and 71% of children with epilepsy achieve seizure freedom, whereas 7% to 20% have drug-resistant epilepsy. The definition of drug resistance has not been consistent across studies, and there is a lack of contemporary population-based data. We used data from a large nationwide child cohort to provide such information, implementing the current standard definition of drug resistance...
May 22, 2018: Pediatrics
https://www.readbyqxmd.com/read/29788414/the-contribution-of-genetic-variation-of-streptococcus-pneumoniae-to-the-clinical-manifestation-of-invasive-pneumococcal-disease
#9
Amelieke J H Cremers, Fredrick M Mobegi, Christa van der Gaast-de Jongh, Michelle van Weert, Fred J van Opzeeland, Minna Vehkala, Mirjam J Knol, Hester J Bootsma, Niko Välimäki, Nicholas J Croucher, Jacques F Meis, Stephen Bentley, Sacha A F T van Hijum, Jukka Corander, Aldert L Zomer, Gerben Ferwerda, Marien I de Jonge
Background: Different clinical manifestations of invasive pneumococcal disease (IPD) have thus far mainly been explained by patient characteristics. Here we studied the contribution of pneumococcal genetic variation to IPD phenotype. Methods: The index cohort consisted of 349 patients admitted to two Dutch hospitals between 2000-2011 with pneumococcal bacteraemia. We performed genome-wide association studies to identify pneumococcal lineages, genes and allelic variants associated with 23 clinical IPD phenotypes...
May 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29787574/child-morbidity-and-mortality-associated-with-alternative-policy-responses-to-the-economic-crisis-in-brazil-a-nationwide-microsimulation-study
#10
Davide Rasella, Sanjay Basu, Thomas Hone, Romulo Paes-Sousa, Carlos Octávio Ocké-Reis, Christopher Millett
BACKGROUND: Since 2015, a major economic crisis in Brazil has led to increasing poverty and the implementation of long-term fiscal austerity measures that will substantially reduce expenditure on social welfare programmes as a percentage of the country's GDP over the next 20 years. The Bolsa Família Programme (BFP)-one of the largest conditional cash transfer programmes in the world-and the nationwide primary healthcare strategy (Estratégia Saúde da Família [ESF]) are affected by fiscal austerity, despite being among the policy interventions with the strongest estimated impact on child mortality in the country...
May 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29785965/inflammatory-bowel-disease-increases-the-risk-of-parkinson-s-disease-a-danish-nationwide-cohort-study-1977-2014
#11
Marie Villumsen, Susana Aznar, Bente Pakkenberg, Tine Jess, Tomasz Brudek
OBJECTIVE: Intestinal inflammation has been suggested to play a role in development of Parkinson's disease (PD) and multiple system atrophy (MSA). To test the hypothesis that IBD is associated with risk of PD and MSA, we performed a nationwide population-based cohort study. DESIGN: The cohort consisted of all individuals diagnosed with IBD in Denmark during 1977-2014 (n=76 477) and non-IBD individuals from the general population, who were comparable in terms of gender, age and vital status (n=7 548 259)...
May 21, 2018: Gut
https://www.readbyqxmd.com/read/29785462/the-prognostic-value-of-tumour-stroma-ratio-and-tumour-budding-in-stage-ii-colon-cancer-a-nationwide-population-based-study
#12
Ann Christina Eriksen, Flemming B Sørensen, Jan Lindebjerg, Henrik Hager, René dePont Christensen, Sanne Kjær-Frifeldt, Torben F Hansen
PURPOSE: High-risk patients with stage II colon cancer (CC) may benefit from adjuvant chemotherapy, but additional prognostic markers are needed for better stratification. We investigated the prognostic value of tumour stroma ratio (TSR) and tumour budding (TB). METHODS: A nationwide population-based cohort of 573 patients with stage II CC was included. TSR was scored on hematoxylin and eosin sections as low TSR (> 50% stroma) and high TSR (≤ 50% stroma)...
May 21, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29782543/correction-the-relationship-between-drinking-alcohol-and-esophageal-gastric-or-colorectal-cancer-a-nationwide-population-based-cohort-study-of-south-korea
#13
Yoon Jin Choi, Dong Ho Lee, Kyung-Do Han, Hyun Soo Kim, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim
[This corrects the article DOI: 10.1371/journal.pone.0185778.].
2018: PloS One
https://www.readbyqxmd.com/read/29779713/regional-differences-in-electronic-medical-record-adoption-in-japan-a-nationwide-longitudinal-ecological-study
#14
Hideaki Kawaguchi, Soichi Koike, Kazuhiko Ohe
PURPOSE: Regional differences in the adoption of electronic medical records (EMR) are a major problem, yet little is known about these differences internationally. We analyzed regional differences in EMR adoption in Japan and evaluated factors associated with these differences. METHODS: This nationwide ecological study used secondary data from all secondary medical service areas (SMSAs) in fiscal years 2008 (n = 348) and 2014 (n = 344). For each SMSA we collected the following information from a Japanese national database: the number of medical facilities that had adopted EMR, the population density, the average per capita income, the number of working doctors per 1000 people, and the proportion of interns to all working doctors...
July 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29778776/identification-and-medical-utilization-of-incident-cases-of-alcohol-dependence-a-population-based-case-control-study
#15
Chun-Hung Pan, Min-Shan Li, Tien-Wey Yang, Ming-Chyi Huang, Sheng-Shiang Su, Yen-Ni Hung, Chiao-Chicy Chen, Chian-Jue Kuo
BACKGROUND: Patients with alcohol dependence (AD) often seek help from medical professionals due to alcohol-related diseases, but the overall distribution of medical specialties identifying new AD cases is unclear. We investigated how such cases were identified and how medical resources were utilized before the identification of AD in a nationwide cohort. METHODS: We enrolled a population-based cohort (N = 1,000,000) using the National Health Insurance Research Database of Taiwan; 8181 cases with incident AD were retrieved between January 1, 2000, and December 31, 2010...
May 5, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29778099/general-practitioners-can-increase-participation-in-cervical-cancer-screening-a-model-program-in-hungary
#16
Anikó Gyulai, Attila Nagy, Vera Pataki, Dóra Tonté, Róza Ádány, Zoltán Vokó
BACKGROUND: Cervical cancer is a preventable disease. Unfortunately, its mortality is high in Hungary: 9.2 deaths /100000 women/year in 2015. The Hungarian organized, nationwide cervical screening program was launched in 2003, but it could improve the coverage rate of cervical cancer screening only by a few percentage points. The vast majority of women still uses opportunistic screening and the organized screening program had little impact on participation by women who never or rarely consult their gynecologists...
May 19, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29777842/nationally-representative-readmission-factors-in-patients-with-claudication-and-critical-limb-ischemia
#17
Rennier A Martinez, Michelle Shnayder, Joshua Parreco, Lukas Gaffney, Marcus Eby, Nicholas Cortolillo, Michael Lopez, Jack Zeltzer
INTRODUCTION: Hospital readmissions are not only associated with increased mortality, morbidity and costs but also, with current healthcare reform, tied to significant financial and administrative penalties. Some studies show that patients undergoing vascular surgery may have higher than average readmission rates. The recently released Nationwide Readmission Database (NRD) is the most comprehensive national source of readmission data, gathering discharge information from 22 geographically dispersed states, accounting for 51...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777536/periodontitis-and-dental-scaling-associated-with-pyogenic-liver-abscess-a-population-based-case-control-study
#18
Y-T Yeh, B-Y Wang, C-W Lin, S-F Yang, S-W Ho, H-W Yeh, J-Y Huang, Y-C Chang, C-B Yeh
BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the relationship between periodontitis, dental scaling (DS) and pyogenic liver abscesses (PLAs). MATERIAL AND METHODS: A nationwide population-based case-control study was applied using data from the National Health Insurance Research Database in Taiwan. We identified and enrolled 691 PLA patients, who were individually matched by age and sex to 2764 controls. RESULTS: Conditional logistic regression was applied to estimate adjusted odds ratios (aORs) in patients with exposure to periodontitis and DS before PLA...
May 18, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29777238/impact-of-body-mass-index-and-body-weight-variabilities-on-mortality-a-nationwide-cohort-study
#19
Ga Eun Nam, Kyung Hwan Cho, Kyungdo Han, Byoungduck Han, Sung Jung Cho, Yong Kyun Roh, Seon Mee Kim, Youn Seon Choi, Do Hoon Kim, Yang Hyun Kim, Yong Gyu Park
BACKGROUND/OBJECTIVES: There is limited information regarding the impact of body mass index (BMI) and body weight (BWt) variabilities on mortality. This study aimed to investigate the association between BMI, BWt variabilities and subsequent mortality in the Korean population. SUBJECTS/METHODS: This study used a representative sample cohort enrolled in the national health examination program conducted by the Korean National Health Insurance Service, and 125,391 individuals were included and followed up until 2013 (mean follow-up period = 84 months)...
May 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29774378/interpersonal-and-institutional-ethnic-discrimination-and-mental-health-in-a-random-sample-of-palestinian-minority-men-smokers-in-israel
#20
Nihaya Daoud, Meiyin Gao, Amira Osman, Carles Muntaner
PURPOSE: We sought to extend research into the health effects of discrimination to a non-Western context. We examined the associations between interpersonal and institutional ethnic discrimination, and anxiety and depression among Palestinian-Arab minority men citizens of Israel. METHODS: We used data from a nationwide stratified random sample of 964 Arab men in Israel, current or former smokers (age 18-64), who were interviewed as part of a 2012-2013 study on cessation...
May 17, 2018: Social Psychiatry and Psychiatric Epidemiology
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