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Gilles Lavigne

Yoshitaka Suzuki, Samar Khoury, Héjar El-Khatib, Jean-Marc Chauny, Jean Paquet, Jean-François Giguère, Ronald Denis, Nadia Gosselin, Gilles J Lavigne, Caroline Arbour
OBJECTIVE: Hypersomnia is frequently reported after mild traumatic brain injury (mTBI), but its cause(s) remain elusive. This study examined sleep/wake activity after mTBI and its association with pain, a comorbidity often associated with insomnia. METHODS: Actigraphy recording was performed for 7 ± 2 consecutive days in 56 individuals at one month post-mTBI (64% male; 38 ± 12 years), 24 individuals at one year post-mTBI (58% male; 44 ± 11years), and in 20 controls (50% male; 37 ± 12 years)...
May 2017: Sleep Medicine
Jean-Marc Chauny, Martin Marquis, Jean Paquet, Gilles Lavigne, Alexis Cournoyer, Christiane Manzini, Raoul Daoust
OBJECTIVE: The management of acute pain constitutes an essential skill of emergency department (ED) physicians. However, the accurate assessment of pain intensity and relief represents a clinically challenging undertaking. Some studies have proposed to define effective pain relief as the patient's refusal for additional analgesic administration. The aim of this study was to verify whether such a refusal is effectively indicative of pain relief. METHODS: This prospective cohort study included ED patients who received single or multiple doses of pain medication for an acute pain problem...
March 15, 2017: CJEM
Samar Khoury, Maria Clotilde Carra, Nelly Huynh, Jacques Montplaisir, Gilles J Lavigne
STUDY OBJECTIVES: Sleep bruxism (SB) is characterized by tooth grinding and jaw clenching during sleep. Familial factors may contribute to the occurrence of SB. This study aims are: (1) revisit the prevalence and characteristics of SB in a large cross-sectional survey and assess familial aggregation of SB, (2) assess comorbidity such as insomnia and pain, (3) compare survey data in a subset of subjects diagnosed using polysomnography research criteria. METHODS: A sample of 6,357 individuals from the general population in Quebec, Canada, undertook an online survey to assess the prevalence of SB, comorbidities, and familial aggregation...
November 1, 2016: Sleep
Caroline Arbour, Andrée-Ann Baril, Harrison J Westwick, Marie-Julie Potvin, Danielle Gilbert, Jean-François Giguère, Gilles J Lavigne, Alex Desautels, Francis Bernard, Steven Laureys, Nadia Gosselin
OBJECTIVE: Posttraumatic amnesia is superior to the initial Glasgow Coma Scale score for predicting traumatic brain injury recovery, but it takes days/weeks to assess. Here, we examined whether return of visual fixation-a potential marker of higher cognitive function-within 24 hours of ICU admission could be used as an early predictor of traumatic brain injury recovery. DESIGN: Two-phase cohort study. SETTING: Level-I trauma ICU. PATIENTS: Moderate-to-severe traumatic brain injury discharged alive between 2010 and 2013...
December 2016: Critical Care Medicine
Gilles J Lavigne
No abstract text is available yet for this article.
2016: Pain Research & Management: the Journal of the Canadian Pain Society
Geneviève Chaput, Susanne P Lajoie, Laura M Naismith, Gilles Lavigne
Background. Identifying which patients are most likely to be at risk of chronic pain and other postconcussion symptoms following mild traumatic brain injury (MTBI) is a difficult clinical challenge. Objectives. To examine the relationship between pain catastrophizing, defined as the exaggerated negative appraisal of a pain experience, and early MTBI outcome. Methods. This cross-sectional design included 58 patients diagnosed with a MTBI. In addition to medical chart review, postconcussion symptoms were assessed by self-report at 1 month (Time 1) and 8 weeks (Time 2) after MTBI...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
Elham Emami, Huy Phan The Nguyen, Pierre Rompré, Gilles J Lavigne, Nelly T Huynh
PURPOSE: The effect of nocturnal wear of denture on sleep quality and integrity is still not well understood. Therefore, this systematic review was conducted to provide evidence on this topic. METHODS: Electronic searches were conducted from 1964 up to September 2015, using MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. Only publications in English or French, in which sleep quality of edentate adult individuals wearing dentures at night was compared to those not wearing were included in the review...
June 25, 2016: Sleep & Breathing, Schlaf & Atmung
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
Andrew S Decker, Gabriela C Cipriano, Gill Tsouri, Jill E Lavigne
Objective. To assess and improve student adherence to hand hygiene indications using radio frequency identification (RFID) enabled hand hygiene stations and performance report cards. Design. Students volunteered to wear RFID-enabled hospital employee nametags to monitor their adherence to hand-hygiene indications. After training in World Health Organization (WHO) hand hygiene methods and indications, student were instructed to treat the classroom as a patient care area. Report cards illustrating individual performance were distributed via e-mail to students at the middle and end of each 5-day observation period...
April 25, 2016: American Journal of Pharmaceutical Education
Marie-Lou Filiatrault, Jean-Marc Chauny, Raoul Daoust, Marie-Pier Roy, Ronald Denis, Gilles Lavigne
STUDY OBJECTIVE: Opioids are associated with higher risk for ataxic breathing and sleep apnea. We conducted a systematic literature review and meta-analysis to assess the influence of long-term opioid use on the apnea-hypopnea and central apnea indices (AHI and CAI, respectively). METHODS: A systematic review protocol (Cochrane Handbook guidelines) was developed for the search and analysis. We searched Embase, Medline, ACP Journal Club, and Cochrane Database up to November 2014 for three topics: (1) narcotics, (2) sleep apnea, and (3) apnea-hypopnea index...
April 15, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Soumia Brahmi, Abdelaziz Touati, Axelle Cadière, Nassima Djahmi, Alix Pantel, Albert Sotto, Jean-Philippe Lavigne, Catherine Dunyach-Remy
To determine the occurrence of carbapenem-resistantAcinetobacter baumanniiin fish fished from the Mediterranean Sea near the Bejaia coast (Algeria), we studied 300 gills and gut samples that had been randomly and prospectively collected during 1 year. After screening on selective agar media, using PCR arrays and whole-genome sequencing, we identified for the first time two OXA-23-producingA. baumanniistrains belonging to the widespread sequence type 2 (ST2)/international clone II and harboring aminoglycoside-modifying enzymes [aac(6')-Ib andaac(3')-I genes]...
April 2016: Antimicrobial Agents and Chemotherapy
Florian Chouchou, Jean-Marc Chauny, Pierre Rainville, Gilles J Lavigne
The placebo effect is a neurobiological and psychophysiological process known to influence perceived pain relief. Optimization of placebo analgesia may contribute to the clinical efficacy and effectiveness of medication for acute and chronic pain management. We know that the placebo effect operates through two main mechanisms, expectations and learning, which is also influenced by sleep. Moreover, a recent study suggested that rapid eye movement (REM) sleep is associated with modulation of expectation-mediated placebo analgesia...
2015: PloS One
Gilles Lavigne
No abstract text is available yet for this article.
November 19, 2015: Pain Research & Management: the Journal of the Canadian Pain Society
Miku Saito, Taihiko Yamaguchi, Saki Mikami, Kazuhiko Watanabe, Akihito Gotouda, Kazuki Okada, Ryuki Hishikawa, Eiji Shibuya, Yoshie Shibuya, Gilles Lavigne
PURPOSE: No definitive associations or causal relationships have been determined between obstructive sleep apnea-hypopnea (OSAH) and sleep bruxism (SB). The purpose of this study was to investigate, in a population reporting awareness of both OSAH and SB, the associations between each specific breathing and jaw muscle event. METHODS: Polysomnography and audio-video data of 59 patients reporting concomitant OSAH and SB history were analyzed. Masseteric bursts after sleep onset were scored and classified into three categories: (1) sleep rhythmic masticatory muscle activity with SB (RMMA/SB), (2) sleep oromotor activity other than RMMA/SB (Sleep-OMA), and (3) wake oromotor activity after sleep onset (Wake-OMA)...
May 2016: Sleep & Breathing, Schlaf & Atmung
Jean-Marc Chauny, Jean Paquet, Gilles Lavigne, Martin Marquis, Raoul Daoust
Percentage of pain intensity difference (PercentPID) is a recognized way of evaluating pain relief with an 11-point numerical rating scale (NRS) but is not without flaws. A new metric, the slope of relative pain intensity difference (SlopePID), which consists in dividing PercentPID by the time between 2 pain measurements, is proposed. This study aims to validate SlopePID with 3 measures of subjective pain relief: a 5-category relief scale (not, a little, moderate, very, complete), a 2-category relief question ("I'm relieved," "I'm not relieved"), and a single-item question, "Wanting other medication to treat pain?" (Yes/No)...
February 2016: Pain
Geneviève Chaput, Susanne P Lajoie, Laura M Naismith, Gilles Lavigne
No abstract text is available yet for this article.
September 10, 2015: Pain Research & Management: the Journal of the Canadian Pain Society
Maria Clotilde Carra, Nelly Huynh, Bernard Fleury, Gilles Lavigne
Sleep bruxism (SB) is a common sleep-related jaw motor disorder observed in 8% of the adult population. SB diagnosis is based on history of tooth grinding and clenching and is confirmed by the polysomnographic recording of the electromyographic activity of jaw muscles during sleep. SB may be associated with orofacial pain, headaches, and sleep-disordered breathing. Managing SB cannot be done without a comprehensive clinical and, when indicated, polysomnographic differential diagnosis of other comorbidities, which need to be taken into account to select the best treatment approach...
September 2015: Sleep Medicine Clinics
Marnix H Medema, Renzo Kottmann, Pelin Yilmaz, Matthew Cummings, John B Biggins, Kai Blin, Irene de Bruijn, Yit Heng Chooi, Jan Claesen, R Cameron Coates, Pablo Cruz-Morales, Srikanth Duddela, Stephanie Düsterhus, Daniel J Edwards, David P Fewer, Neha Garg, Christoph Geiger, Juan Pablo Gomez-Escribano, Anja Greule, Michalis Hadjithomas, Anthony S Haines, Eric J N Helfrich, Matthew L Hillwig, Keishi Ishida, Adam C Jones, Carla S Jones, Katrin Jungmann, Carsten Kegler, Hyun Uk Kim, Peter Kötter, Daniel Krug, Joleen Masschelein, Alexey V Melnik, Simone M Mantovani, Emily A Monroe, Marcus Moore, Nathan Moss, Hans-Wilhelm Nützmann, Guohui Pan, Amrita Pati, Daniel Petras, F Jerry Reen, Federico Rosconi, Zhe Rui, Zhenhua Tian, Nicholas J Tobias, Yuta Tsunematsu, Philipp Wiemann, Elizabeth Wyckoff, Xiaohui Yan, Grace Yim, Fengan Yu, Yunchang Xie, Bertrand Aigle, Alexander K Apel, Carl J Balibar, Emily P Balskus, Francisco Barona-Gómez, Andreas Bechthold, Helge B Bode, Rainer Borriss, Sean F Brady, Axel A Brakhage, Patrick Caffrey, Yi-Qiang Cheng, Jon Clardy, Russell J Cox, René De Mot, Stefano Donadio, Mohamed S Donia, Wilfred A van der Donk, Pieter C Dorrestein, Sean Doyle, Arnold J M Driessen, Monika Ehling-Schulz, Karl-Dieter Entian, Michael A Fischbach, Lena Gerwick, William H Gerwick, Harald Gross, Bertolt Gust, Christian Hertweck, Monica Höfte, Susan E Jensen, Jianhua Ju, Leonard Katz, Leonard Kaysser, Jonathan L Klassen, Nancy P Keller, Jan Kormanec, Oscar P Kuipers, Tomohisa Kuzuyama, Nikos C Kyrpides, Hyung-Jin Kwon, Sylvie Lautru, Rob Lavigne, Chia Y Lee, Bai Linquan, Xinyu Liu, Wen Liu, Andriy Luzhetskyy, Taifo Mahmud, Yvonne Mast, Carmen Méndez, Mikko Metsä-Ketelä, Jason Micklefield, Douglas A Mitchell, Bradley S Moore, Leonilde M Moreira, Rolf Müller, Brett A Neilan, Markus Nett, Jens Nielsen, Fergal O'Gara, Hideaki Oikawa, Anne Osbourn, Marcia S Osburne, Bohdan Ostash, Shelley M Payne, Jean-Luc Pernodet, Miroslav Petricek, Jörn Piel, Olivier Ploux, Jos M Raaijmakers, José A Salas, Esther K Schmitt, Barry Scott, Ryan F Seipke, Ben Shen, David H Sherman, Kaarina Sivonen, Michael J Smanski, Margherita Sosio, Evi Stegmann, Roderich D Süssmuth, Kapil Tahlan, Christopher M Thomas, Yi Tang, Andrew W Truman, Muriel Viaud, Jonathan D Walton, Christopher T Walsh, Tilmann Weber, Gilles P van Wezel, Barrie Wilkinson, Joanne M Willey, Wolfgang Wohlleben, Gerard D Wright, Nadine Ziemert, Changsheng Zhang, Sergey B Zotchev, Rainer Breitling, Eriko Takano, Frank Oliver Glöckner
No abstract text is available yet for this article.
September 2015: Nature Chemical Biology
Louise Cullen, Rebecca Weiser, Tomasz Olszak, Rita F Maldonado, Ana S Moreira, Lisa Slachmuylders, Gilles Brackman, Tsvetelina S Paunova-Krasteva, Paulina Zarnowiec, Grzegorz Czerwonka, James Reilly, Pavel Drevinek, Wieslaw Kaca, Oto Melter, Anthony De Soyza, Audrey Perry, Craig Winstanley, Stoyanka R Stoitsova, Rob Lavigne, Eshwar Mahenthiralingam, Isabel Sá-Correia, Tom Coenye, Zuzanna Drulis-Kawa, Daria Augustyniak, Miguel A Valvano, Siobhán McClean
Pseudomonas aeruginosa causes chronic lung infections in people with cystic fibrosis (CF) and acute opportunistic infections in people without CF. Forty-two P. aeruginosa strains from a range of clinical and environmental sources were collated into a single reference strain panel to harmonise research on this diverse opportunistic pathogen. To facilitate further harmonized and comparable research on P. aeruginosa, we characterized the panel strains for growth rates, motility, virulence in the Galleria mellonella infection model, pyocyanin and alginate production, mucoid phenotype, LPS pattern, biofilm formation, urease activity, and antimicrobial and phage susceptibilities...
October 2015: Microbiology
Pierre Mayer, Raphael Heinzer, Gilles Lavigne
Sleep bruxism (SB) consists of involuntary episodic and repetitive jaw muscle activity characterized by occasional tooth grinding or jaw clenching during sleep. Prevalence decreases from 20% to 14% in childhood to 8% to 3% in adulthood. Although the causes and mechanisms of idiopathic primary SB are unknown, putative candidates include psychologic risk factors (eg, anxiety, stress due to life events, hypervigilance) and sleep physiologic reactivity (eg, sleep arousals with autonomic activity, breathing events)...
January 2016: Chest
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