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https://www.readbyqxmd.com/read/29031209/relative-value-of-three-whole-body-mr-approaches-for-pet-mr-including-gadofosveset-enhanced-mr-in-comparison-to-pet-ct
#1
Piotr Obara, Andreas Loening, Valentina Taviani, Andrei Iagaru, Brian A Hargreaves, Shreyas Vasanawala
PURPOSE: Evaluate MR protocol for PET-MR including coronal DWI (cDWI), fat-suppressed T2 (T2w), and gadofosveset-enhanced T1 (CE). MATERIALS AND METHODS: 18 patients underwent same-day PET-CT and PET-MR. Image quality and performance of each sequence, and combination of all three sequences, was evaluated with respect to PET-CT. RESULTS: Lesion conspicuity was best on cDWI, while delineation was best on CE. Considering all three sequences combined, both readers showed good sensitivity and specificity (>80%)...
September 29, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29029006/large-scale-assessment-of-aortic-stenosis-facing-the-next-cardiac-epidemic
#2
Javier Ramos, Juan Manuel Monteagudo, Teresa González-Alujas, María Eugenia Fuentes, Marta Sitges, María Luisa Peña, Fernando Carrasco-Chinchilla, Tomás Echeverría, Alberto Bouzas, José Francisco Forteza Alberti, Dolores Mesa, Jesús María De La Hera, José Luis Zamorano
Aims: Aortic stenosis (AS) is the most frequent valvular disease in developed countries. As society grows older, the prevalence of AS increases. However, the real burden, current aetiology, severity distribution, and echocardiographic patterns of AS are not fully clear. The aim of the present study is to provide an accurate overall picture of AS, focusing on its epidemiology, aetiology, and echocardiographic features. Methods and results: A total of 29 502 consecutive echocardiograpies were prospectively included in this multicentre study...
September 28, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29028758/mr-neurography-of-lumbosacral-plexus-in-failed-back-surgery-syndrome
#3
Riham Dessouky, Mohammed Khaleel, Dalia N Khalifa, Hazim I Tantawy, Avneesh Chhabra
STUDY DESIGN: Retrospective clinical case series. OBJECTIVE: To study the role of MRN of lumbosacral plexus in management of patients with FBSS. SUMMARY OF BACKGROUND DATA: Failed back surgery syndrome (FBSS) is one of the major problems in health care, affecting up to 40% of patients following spine surgery. To date, no imaging modality has been used to effectively classify nerve compression, since nerve injuries are challenging to detect on conventional lumbar spine MRI...
October 12, 2017: Spine
https://www.readbyqxmd.com/read/29028511/a-pictorial-review-of-diagnostic-pitfalls-of-developmental-anomalies-and-variants-in-pancreatic-imaging
#4
REVIEW
Jong Eun Lee, Sang Soo Shin, Shin Jung Kim, Suk Hee Heo, Hyo Soon Lim, Jin Woong Kim, Yong Yeon Jeong
Developmental anomalies and anatomic variants of the pancreas vary widely, and most of them are encountered incidentally during radiologic evaluation. However, some of these anomalies and variants are potentially pathologic and may cause various clinical presentations in childhood or adulthood. The early identification of these entities in various imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance (MR) imaging would be valuable in making correct diagnoses and, in turn, preventing unnecessary additional procedures...
September 19, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29028461/antibiotic-impregnated-central-venous-catheters-do-not-change-antibiotic-resistance-patterns
#5
Isaiah R Turnbull, Sara A Buckman, Christopher B Horn, Grant V Bochicchio, John E Mazuski
BACKGROUND: Antibiotic-impregnated central venous catheters (CVCs) decrease the incidence of infection in high-risk patients. However, use of these catheters carries the hypothetical risk of inducing antibiotic resistance. We hypothesized that routine use of minocycline and rifampin-impregnated catheters (MR-CVC) in a single intensive care unit (ICU) would change the resistance profile for Staphylococcus aureus. METHODS: We reviewed antibiotic susceptibilities of S...
October 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29028326/ratiometric-ph-imaging-with-a-co-ii-2-mri-probe-via-cest-effects-of-opposing-ph-dependences
#6
Agnes E Thorarinsdottir, Kang Du, James H P Collins, T David Harris
We report a Co2-based magnetic resonance (MR) probe that enables the ratiometric quantitation and imaging of pH through chemical exchange saturation transfer (CEST). This approach is illustrated in a series of air- and water-stable Co(II)2 complexes featuring CEST-active tetra(carboxamide) and/or hydroxyl-substituted bisphosphonate ligands. For the complex bearing both ligand types, variable-pH CEST and NMR analyses reveal highly-shifted carboxamide and hydroxyl peaks with intensities that increase and decrease with increasing pH, respectively...
October 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29028194/temporal-scalability-of-dynamic-volume-data-using-mesh-compensated-wavelet-lifting
#7
Wolfgang Schnurrer, Niklas Pallast, Thomas Richter, Andre Kaup
Due to their high resolution, dynamic medical 2D+t and 3D+t volumes from computed tomography (CT) and magnetic resonance tomography (MR) reach a size which makes them very unhandy for teleradiologic applications. A lossless scalable representation offers the advantage of a down-scaled version which can be used for orientation or previewing, while the remaining information for reconstructing the full resolution is transmitted on demand. The wavelet transform offers the desired scalability. A very high quality of the lowpass sub-band is crucial in order to use it as a down-scaled representation...
October 12, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29027857/is-there-added-value-in-obtaining-cervical-spine-mri-in-the-assessment-of-nontraumatic-angiographically-negative-subarachnoid-hemorrhage-a-retrospective-study-and-meta-analysis-of-the-literature
#8
Gelareh Sadigh, Chad A Holder, Jeffrey M Switchenko, Seena Dehkharghani, Jason W Allen
OBJECTIVE Diagnostic algorithms for nontraumatic angiographically negative subarachnoid hemorrhage (AN-SAH) vary, and the optimal method remains subject to debate. This study assessed the added value of cervical spine MRI in identifying a cause for nontraumatic AN-SAH. METHODS Consecutive patients 18 years of age or older who presented with nontraumatic SAH between February 1, 2009, and October 31, 2014, with negative cerebrovascular catheter angiography and subsequent cervical MRI were studied. Patients with intraparenchymal, subdural, or epidural hemorrhage; recent trauma; or known vascular malformations were excluded...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29027841/diffusion-tensor-tractography-in-cerebral-small-vessel-disease-correlation-with-cognitive-function
#9
Maria M D'Souza, S P Gorthi, Kunal Vadwala, Richa Trivedi, C Vijayakumar, Prabhjot Kaur, Subash Khushu
Background Patients with cerebral small vessel disease may suffer from varying levels of cognitive deficit and may progress on to vascular dementia. The extent of involvement, as seen on conventional magnetic resonance (MR) measures, correlates poorly with the level of cognitive decline. The purpose of this study was to investigate the utility of diffusion tensor imaging (DTI) as a marker for white matter damage in small vessel disease and to assess its correlation with cognitive function. Methods Thirty consecutive patients with cerebral small vessel disease underwent conventional MR imaging, DTI, and neuropsychological assessment...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#10
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29027261/prognostic-significance-of-additional-chromosomal-abnormalities-at-the-time-of-diagnosis-in-patients-with-chronic-myeloid-leukemia-treated-with-frontline-tyrosine-kinase-inhibitors
#11
Ahmad Alhuraiji, Hagop Kantarjian, Prajwal Boddu, Farhad Ravandi, Gautam Borthakur, Courtney DiNardo, Naval Daver, Tapan Kadia, Naveen Pemmaraju, Sherry Pierce, Guillermo Garcia-Manero, William Wierda, Srdan Verstovsek, Elias Jabbour, Jorge Cortes
Additional cytogenetic abnormalities (ACA) are considered a high risk feature in chronic myeloid leukemia (CML). However, its prognostic significance at the time of diagnosis in the setting of new tyrosine kinase inhibitors (TKIs) is less well understood. Patients with CML in CP with or without ACA at diagnosis treated with frontline TKIs in prospective clinical trials were analyzed for outcomes. Among 603 patients treated, 29 (5%) had ACA. Patients with ACA included 2 of 72 (2.8%) treated with imatinib 400 mg, 9 of 207 (4...
October 13, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/29027094/multimodal-functional-neuroimaging-by-simultaneous-bold-fmri-and-fiber-optic-calcium-recordings-and-optogenetic-control
#12
REVIEW
Franziska Albers, Lydia Wachsmuth, Timo Mauritz van Alst, Cornelius Faber
Recent developments of optogenetic tools and fluorescence-based calcium recording techniques enable the manipulation and monitoring of neural circuits on a cellular level. Non-invasive imaging of brain networks, however, requires the application of methods such as blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI), which is commonly used for functional neuroimaging. While BOLD fMRI provides brain-wide non-invasive reading of the hemodynamic response, it is only an indirect measure of neural activity...
October 12, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29027008/lateral-epicondylitis-associations-of-mr-imaging-and-clinical-assessments-with-treatment-options-in-patients-receiving-conservative-and-arthroscopic-managements
#13
Ji Young Jeon, Min Hee Lee, In-Ho Jeon, Hye Won Chung, Sang Hoon Lee, Myung Jin Shin
OBJECTIVES: We assessed the implications of MR imaging with clinical history in lateral epicondylitis management by evaluating imaging and clinical features in patients with lateral epicondylitis treated conservatively or operatively. METHODS: Sixty patients with lateral epicondylitis treated conservatively (n = 38) or operatively (n = 22) from 2011-2015 were included. MR imaging findings of common extensor tendon (CET), lateral collateral ligament (LCL) complex, muscle oedema, ulnar nerve and elbow joint were reviewed...
October 12, 2017: European Radiology
https://www.readbyqxmd.com/read/29026676/spinal-epidural-abscess-report-on-27-cases
#14
Nayil Khursheed, Sultan Dar, Altaf Ramzan, Bashir Fomda, Nisar Humam, Wani Abrar, Sarbjit Singh, Arif Sajad, Masood Mahek, Shoaib Yawar
BACKGROUND: Spinal epidural abscess, although an uncommon disease, often correlates with a high morbidity owing to significant delay in diagnosis. METHODS: In a prospective 5-year study, the clinical and magnetic resonance (MR) findings, treatment protocols, microbiology, and neurological outcomes were analyzed for 27 patients with spinal epidural abscess. RESULTS: Patients were typically middle-aged with underlying diabetes and presented with lumbar abscesses...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29026670/rare-case-of-conus-medullaris-glioblastoma-multiforme-in-a-teenager
#15
Lakhdar Fayçal, Bougrine Mouna, El Abbadi Najia
BACKGROUND: Primary intramedullary spinal glioblastoma multiforme (GBM) lesions are very rare comprising only 1.5% of all spinal cord tumors. These lesions typically result in rapid neurological deterioration and are associated with a very poor prognosis. CASE DESCRIPTION: A 16-year-old male exhibited a slowly progressive paraparesis with urinary incontinence, ultimately resulting in paraplegia. On magnetic resonance (MR), he was diagnosed with an intramedullary GBM of the spinal cord extending from the T9 level through the conus medullaris...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29026095/alterations-of-regional-homogeneity-and-functional-connectivity-in-pituitary-adenoma-patients-with-visual-impairment
#16
Guidong Song, Jicheng Qiu, Chuzhong Li, Jiye Li, Songbai Gui, Haibo Zhu, Yazhuo Zhang
Evidences have showed that the deprivation of vision can considerably alter the resting-state activity both within and beyond the visual cortices. However, the functional changes of the brain cortices related to partially vision-deprivation are still largely unknown. Using resting-state functional MR imaging, we quantitatively evaluated the regional homogeneity(ReHo) and functional connectivity(FC) changes between 25 pituitary adenoma patients with visual impairment and 25 healthy controls(HCs). Compared with HCs, PAs exhibited significant increased ReHo in the left superior occipital gyrus, bilateral middle occipital gyrus and reduced ReHo in the left inferior frontal gyrus and right middle temporal gyrus...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025988/advanced-methods-for-radiolabelling-nanomedicines-for-multi-modality-nuclear-mr-imaging
#17
Jennifer R Lamb, Jason P Holland
The advent of hybrid cameras that combine magnetic resonance imaging with either single-photon emission computed tomography (SPECT/MRI) or positron-emission tomography (PET/MRI) has stimulated growing interest in developing multi-modality imaging probes. Countless options are available for fusing magnetically active species with positron- or gamma-ray emitting radionuclides. The initial problem is one of choice: which chemical systems are a suitable basis for developing hybrid imaging agents? Any attempt to answer this question must also address how the physical, chemical, and biological properties of a unified imaging agent can be tailored to ensure that optimum specificity and contrast is achieved simultaneously for both imaging modalities...
October 12, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29025721/predictive-models-in-differentiating-vertebral-lesions-using-multiparametric-mri
#18
R Rathore, A Parihar, D K Dwivedi, A K Dwivedi, N Kohli, R K Garg, A Chandra
BACKGROUND AND PURPOSE: Conventional MR imaging has high sensitivity but limited specificity in differentiating various vertebral lesions. We aimed to assess the ability of multiparametric MR imaging in differentiating spinal vertebral lesions and to develop statistical models for predicting the probability of malignant vertebral lesions. MATERIALS AND METHODS: One hundred twenty-six consecutive patients underwent multiparametric MRI (conventional MR imaging, diffusion-weighted MR imaging, and in-phase/opposed-phase imaging) for vertebral lesions...
October 12, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29025679/relation-of-residual-mitral-regurgitation-despite-elevated-mitral-gradients-to-risk-of-heart-failure-hospitalization-after-mitraclip-repair
#19
Richard Cheng, Sam Dawkins, Emily Tat, Moody Makar, Asma Hussaini, Raj R Makkar, Alfredo Trento, Robert J Siegel, Saibal Kar
Achieving minimal residual mitral regurgitation (MR) after percutaneous MitraClip repair is limited by iatrogenic mitral stenosis. It is unknown whether allowing moderately elevated postprocedural mean mitral gradients (MMGs) to achieve < moderate residual MR is preferable to moderate residual regurgitation. Patients with less-than-moderate residual MR but a MMG of ≥5 mm Hg (Group 1) were compared with patients with moderate residual MR (Group 2). The primary end point was heart failure hospitalization...
November 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29025647/glucose-functionalized-carbon-quantum-dot-containing-organic-radical-for-optical-mr-dual-modality-bioimaging
#20
Xiaodan Lu, Zhide Zhang, Qi Xia, Meirong Hou, Chenggong Yan, Zelong Chen, Yikai Xu, Ruiyuan Liu
The organic paramagnetic compounds nitroxides have great potential as magnetic resonance imaging (MRI) contrast agents. Herein, we report the synthesis and characterization of glucose modified carbon quantum dot containing 2,2,6,6-tetramethyl-piperidinooxy (TEMPO) for targeted bimodal MR/optical imaging of tumor cells. CQD-TEMPO-Glu shows the greatest potentials for bioimaging applications in view of low cytotoxicity, good biocompatibility, green fluorescence emission and high T1 relaxivities. The in vitro MR and optical imaging results confirm enhanced cellular internalization of CQD-TEMPO-Glu in cancer cells through GLUT mediated endocytosis...
January 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
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