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Parotid gland

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https://www.readbyqxmd.com/read/27911406/ultrasound-guided-botulinum-toxin-a-injections-a-method-of-treating-sialorrhea
#1
Pierangelo Barbero, Marco Busso, Carlo Alberto Artusi, Stefania De Mercanti, Marco Tinivella, Andrea Veltri, Luca Durelli, Marinella Clerico
Neurological diseases can be complicated by sialorrhea, an excessive flow of saliva. Patients suffering from moderate to severe sialorrhea have an impaired quality of life, often worsened by correlated complications such as aspiration pneumonia, oral infections, dental caries, and maceration of the skin. Diverse therapeutic approaches have been proposed for the treatment of sialorrhea, including surgery and the use of anticholinergic agents, with limited results and the possible occurrence of serious adverse events...
November 9, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27908305/abatacept-treatment-of-patients-with-primary-sj%C3%A3-gren-s-syndrome-results-in-a-decrease-of-germinal-centres-in-salivary-gland-tissue
#2
Erlin A Haacke, Bert van der Vegt, Petra M Meiners, Arjan Vissink, Fred K L Spijkervet, Hendrika Bootsma, Frans G M Kroese
OBJECTIVES: The aim of this study was to assess the histopathological changes in parotid gland tissue of primary Sjögren's syndrome (pSS) patients treated with abatacept. METHODS: In all 15 pSS patients included in the open-label Active Sjögren Abatacept Pilot (ASAP, 8 abatacept infusions) study parotid gland biopsies were taken before treatment and at 24 weeks of follow up. Biopsies were analysed for pSS-related histopathological features and placed in context of clini- cal responsiveness as assessed with EULAR Sjögren's syndrome disease activity index (ESSDAI)...
November 12, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27900250/effect-of-tens-on-stimulation-of-saliva-in-postmenopausal-women-with-or-without-oral-dryness-an-interventional-study
#3
Aravinda Konidena, Dheeraj Sharma, Gagan Puri, Avani Dixit, Deepa Jatti, Rajesh Gupta
BACKGROUND: Decreased estrogen levels in postmenopausal women may cause an increase in oral symptoms including dry mouth, burning sensation of the mouth, and taste alterations. Management of salivary gland hypofunction by various modalities had been tried with variable results and associated side effects or discomfort. AIM: To evaluate the effects of transcutaneous electric nerve stimulation (TENS) on whole salivary flow rate in postmenopausal females with and without oral dryness...
November 2016: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/27895943/congenital-unilateral-agenesis-of-the-parotid-gland-a-case-report-and-review-of-the-literature
#4
Afshin Teymoortash, Stephan Hoch
Congenital unilateral agenesis of the parotid gland is a rare condition with only few cases reported in the literature. A review of 21 cases in the available literature is presented in this article. We report on a further case of a 34-year-old woman with agenesis of the left parotid gland and lipoma of the right cheek. Clinicopathological characteristics of described cases in the literature were discussed.
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27894600/reply-letter-to-texture-analysis-of-parotid-gland-as-a-predictive-factor-of-radiation-induced-xerostomia-a-subset-analysis
#5
Lisanne V van Dijk, Johannes A Langendijk, Nanna M Sijtsema, Roel J H M Steenbakkers
No abstract text is available yet for this article.
November 25, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27890427/internal-and-external-generalizability-of-temporal-dose-response-relationships-for-xerostomia-following-imrt-for-head-and-neck-cancer
#6
Maria Thor, Adepitan A Owosho, Haley D Clark, Jung Hun Oh, Nadeem Riaz, Allan Hovan, Jillian Tsai, Steven D Thomas, Sae Hee K Yom, Jonn S Wu, Joseph M Huryn, Vitali Moiseenko, Nancy Y Lee, Cherry L Estilo, Joseph O Deasy
BACKGROUND AND PURPOSE: To study internal and external generalizability of temporal dose-response relationships for xerostomia after intensity-modulated radiotherapy (IMRT) for head and neck cancer, and to investigate potential amendments of the QUANTEC guidelines. MATERIAL AND METHODS: Objective xerostomia was assessed in 121 patients (nCohort1=55; nCohort2=66) treated to 70Gy@2Gy in 2006-2015. Univariate and multivariate analyses (UVA, MVA with 1000 bootstrap populations) were conducted in Cohort1, and generalizability of the best-performing MVA model was investigated in Cohort2 (performance: AUC, p-values, and Hosmer-Lemeshow p-values (pHL))...
November 24, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27888671/sclerosing-polycystic-adenosis-of-the-parotid-gland-a-systematic-review-and-report-of-2-new-cases
#7
Carlos A Espinosa, Laura Rua, Héctor E Torres, Álvaro Fernández Del Valle, Rui P Fernandes, Juan C Devicente
PURPOSE: We sought to evaluate clinical-epidemiologic aspects, pathologic characteristics, and treatment of sclerosing polycystic adenosis (SPA) of the parotid gland and to report 2 new cases. MATERIALS AND METHODS: We conducted a systematic review following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for studies published in or before June 2016. The inclusion criteria were as follows: final diagnosis of SPA affecting the parotid gland and articles published in Spanish or English...
November 2, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27888340/prognostic-value-of-comorbidities-in-patients-with-carcinoma-of-the-major-salivary-glands
#8
Christoph Becker, Kilian Konrad Kenjiro Dahlem, Jens Pfeiffer
This study aimed at evaluating the influence of comorbidities on outcome and survival in patients with carcinoma of the major salivary glands. Medical records of 109 patients with carcinoma of the major salivary glands treated at a single quaternary medical care and cancer center between 2003 and 2015 were reviewed. Comorbidities were classified according to the Age-Adjusted Charlson Comorbidity Index (ACCI) scoring system. 59 patients were males, 50 were females. Median age was 69 years and the median interval between tumor diagnosis and date of study inclusion was 71 months...
November 25, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27886428/immune-reactivity-after-adenoviral-mediated-aquaporin-1-cdna-transfer-to-human-parotid-glands
#9
Ilias Alevizos, Changyu Zheng, Ana P Cotrim, Corinne M Goldsmith, Linda McCullagh, Theodore Berkowitz, Susan L Strobl, Anatoli Malyguine, William C Kopp, John A Chiorini, Nikolay P Nikolov, Megan Neely, Gabor G Illei, Bruce J Baum
OBJECTIVES: The purpose of this study was to examine the humoral and cellular immune reactivity to adenoviral vector (AdhAQP1) administration in the human parotid gland over the first 42 days of a clinical gene therapy trial. METHODS: Of eleven treated subjects, five were considered as positive responders (Baum et al, 2012). Herein, we measured serum neutralizing antibody titers, circulating cytotoxic lymphocytes, and lymphocyte proliferation in peripheral blood mononuclear cells...
November 25, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27882318/sialendoscopy-and-combined-minimally-invasive-treatment-for-large-parotid-stones
#10
Jan Rotnágl, Šárka Zavázalová, Olexii Vorobiov, Jaromír Astl
Sialendoscopy (SE) represents nowadays one of the standard diagnostic and therapeutic procedures in the treatment of major salivary glands lithiasis. We know from experience that it is successful only in small percentage of patients, when used in monotherapy. However, it represents an indispensable part of all of the combined minimally invasive gland-preserving treatment techniques, the success rate of which is around 90%. In this work, we focused on the role of sialendoscopy in the treatment of patients with larger inflamed fixed stones in glandula parotis...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27875709/iodine-125-interstitial-brachytherapy-for-pediatric-desmoid-type-fibromatosis-of-the-head-and-neck-a-case-report
#11
Wen-Jie Wu, Hua-Qiu Guo, Guang-Yan Yu, Jian-Guo Zhang
Desmoid-type fibromatosis (DF) is a locally aggressive benign soft tissue tumor. It is rarely observed in the head and neck region and is particularly uncommon in the parotid gland. This report describes the case of a 32-month-old girl with DF of the head and neck. The tumor was resected with gross residual tumors. Recurrence occurred 3 months later and then the patient was treated with iodine-125 interstitial brachytherapy. The tumor was completely absent 6 months after brachytherapy. No recurrence was found 60 months after brachytherapy during follow-up...
October 29, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27874161/diffusion-weighted-magnetic-resonance-imaging-in-the-diagnosis-of-parotid-masses-preliminary-results
#12
Zeynel Yologlu, Hasan Aydin, Nalan A Alp, Bilgin K Aribas, Volkan Kizilgoz, Kemal Arda
To demonstrate the diagnostic potentials of MRI, diffusion weighted imaging (DWI), and apparent diffusion coefficient (ADC) mapping in the detection of parotid masses correlated to the histopathological results. Methods: Study design was retrospective. Fifteen patients with parotid gland masses were included as the study group and contralateral normal parotis glands of same patients were taken as the control group. Patients with bilateral parotid gland tumors were excluded, 7 right-sided and 8 left-sided parotid masses were included in the research...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27873327/cost-effectiveness-of-transfacial-gland-preserving-removal-of-parotid-sialoliths
#13
Adrian A Ong, William W Carroll, Shaun A Nguyen, M Boyd Gillespie
OBJECTIVE: Examine outcomes of transfacial gland-preserving removal of difficult parotid stones and compare the cost and operative time to traditional parotidectomy. STUDY DESIGN: Cost-effectiveness analysis and retrospective chart review. METHODS: Patients who underwent transfacial removal of symptomatic parotid sialoliths at a tertiary medical center from June 2010 to July 2015 were evaluated. Outcomes included operative technique, stone size, stone location, complications, and symptom relief...
November 22, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27872417/virtual-touch-quantification-of-the-salivary-glands-for-diagnosis-of-primary-sj%C3%A3-gren-syndrome
#14
Shaoqi Chen, Yukai Wang, Shaoxing Chen, Qiulin Wu, Shigao Chen
OBJECTIVES: To investigate the value of salivary gland stiffness measured by Virtual Touch quantification (VTQ; Siemens Medical Solutions, Erlangen, Germany) for assessment of primary Sjögren syndrome. METHODS: Fifty-four patients with primary Sjögren syndrome, 35 patients without primary Sjögren syndrome (patients with dry mouth and dry eye symptoms), and 52 healthy control volunteers were included in this study. Patients with primary Sjögren syndrome were classified as early or advanced stage by labial gland biopsies...
December 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27872134/metastatic-trichilemmal-carcinoma-in-a-patient-with-breast-cancer
#15
Chrysis Sofianos, Nkhensani Y Chauke, Alexandra Grubnik
Trichilemmal carcinoma (TC) is described as a very rare cancer of the skin adnexa.(1 2) Ninety per cent of the lesions present on the scalp. Prognostic factors in TC are limited to lymph node status and surgical margins, with no statistical significance observed for age or gender of the patient, size of tumour or locoregional recurrence. We present a 46-year-old black patient who developed TC during treatment for breast cancer. Postoperative histology of the scalp lesion excision confirmed no involved margins...
November 21, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27861944/chronic-parotitis-with-multiple-calcifications-clinical-and-sialendoscopic-findings
#16
Emmanuel Jáuregui, Ruwan Kiringoda, William R Ryan, David W Eisele, Jolie L Chang
OBJECTIVES/HYPOTHESIS: To characterize clinical, imaging, and sialendoscopy findings in patients with chronic parotitis and multiple parotid calcifications. STUDY DESIGN: Retrospective review. METHODS: Clinical history, radiographic images and reports, lab tests, and operative reports were reviewed for adult patients with chronic parotitis and multiple parotid calcifications who underwent parotid sialendoscopy. RESULTS: Thirteen of 133 (10%) patients undergoing parotid sialendoscopy for chronic sialadenitis had more than one calcification in the region of the parotid gland...
November 15, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27861380/atheroma-of-the-facial-artery-mimicking-a-parotid-gland-tumor-a-case-report
#17
Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim
INTRODUCTION: Atheroma of the facial artery is an extremely rare disease. CLINICAL FINDINGS/PATIENT CONCERNS: Herein, we report an extremely rare case of an atheroma arising from the facial artery, mimicking a parotid gland tumor. DIAGNOSES: The preoperative diagnosis was a right-sided parotid gland tumor. INTERVENTIONS: We performed removal of the right parotid gland tumor, via a modified face-lift incision. OUTCOMES: Histological examination of the specimen revealed an atheroma of the facial artery...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27861333/isolated-neurosarcoidosis-mimicking-multifocal-meningiomas-a-diagnosis-pitfall-a-case-report
#18
Kun Wang, Xiaoying He, Wei Wang, Huanjiang Niu, Yirong Wang, Xiujun Cai, Shuxu Yang
INTRODUCTION: Neurosarcoidosis accounts for approximately 5% of the sarcoidosis, which develops exclusively in the nervous system and is always difficult to diagnose. We describe a rare case of isolated neurosarcoidosis mimicking as multifocal meningiomas. A 27-year-old male was admitted to our hospital with a history of unconsciousness and convulsion 1 month ago, which was suspected as a seizure. The results showed no abnormalities in complete blood count; serum electrolytes; erythrocyte sedimentation rate and ultrasonography of the liver, pancreas, spleen, kidney and parotid gland, and so on...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27853498/dosimetry-of-three-cone-beam-computerized-tomography-scanners-at-different-fields-of-view-in-terms-of-various-head-and-neck-organs
#19
Sima Nikneshan, Mahmood Reza Aghamiri, Ehsan Moudi, Nika Bahemmat, Hoora Hadian
BACKGROUND: Marketing new radiography devices necessitates documenting their absorbed X-ray doses. Since the current literature lacks studies on new devices, we assessed the doses of two new devices that had not previously been assessed. OBJECTIVES: The new devices were compared to the Promax three dimensional (3D) scanner at two fields of view (FOV) in nine critical head and neck tissues and organs. MATERIALS AND METHODS: Seventeen thermoluminescence dosimeters positioned in an average-sized male RANDO phantom were used to determine the dosimetry of the three cone beam computerized tomography devices (NewTom VGi, NewTom 5G, and Promax 3D) at two field of views (FOVs), one small and one large...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27847831/relapsed-acinic-cell-carcinoma-of-the-parotid-gland-with-diffuse-distant-metastasis-case-report-with-literature-review
#20
Yousef Khelfa, Munthir Mansour, Yousef Abdel-Aziz, Ali Raufi, Krista Denning, Yehuda Lebowicz
Acinic cell carcinoma (ACC) is an uncommon salivary gland neoplasm that generally displays an indolent growth pattern. Most cases arise in the major glands, particularly the parotid. However, it can arise from minor salivary glands in the oral cavity and aero-digestive tract. Although ACC is generally a low-grade malignant tumor, poorly differentiated and high-grade transformed variants exhibit a propensity for late recurrence and metastasis. There are no adequate clinical trials that define the optimal approach to patients with metastatic salivary gland tumors due to its rarity...
October 2016: Journal of Investigative Medicine High Impact Case Reports
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