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Parotid gland

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https://www.readbyqxmd.com/read/28730224/histopathological-and-immunohistochemical-profile-in-primary-sj%C3%A3-gren-s-syndrome
#1
Ştefan Cristian Dinescu, Mircea Cătălin ForŢofoiu, Ana Maria Bumbea, Paulina Lucia Ciurea, Cristina Jana Busuioc, Anca Emanuela Muşetescu
Sjögren's syndrome (SS) is an autoimmune disease characterized by hypofunction of the salivary and lachrymal glands. Main clinical features of SS are sicca symptoms, due to the altered glandular function. Also, in advanced stages, bilateral swelling of the parotid glands can be noted, indicative of severe glandular involvement. Phenotypic expression of various mononuclear cells present in the affected tissue offers additional insight into cellular proliferation, survival, migration, antibody secretion and also the potential of forming tertiary lymphoid tissue, i...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28728321/review-of-the-nomenclature-of-the-retaining-ligaments-of-the-cheek-frequently-confused-terminology
#2
Yeui Seok Seo, Jennifer Kim Song, Tae Suk Oh, Seong Ihl Kwon, Tanvaa Tansatit, Joo Heon Lee
Since the time of its inception within facial anatomy, wide variability in the terminology as well as the location and extent of retaining ligaments has resulted in confusion over nomenclature. Confusion over nomenclature also arises with regard to the subcutaneous ligamentous attachments, and in the anatomic location and extent described, particularly for zygomatic and masseteric ligaments. Certain historical terms-McGregor's patch, the platysma auricular ligament, parotid cutaneous ligament, platysma auricular fascia, temporoparotid fasica (Lore's fascia), anterior platysma-cutaneous ligament, and platysma cutaneous ligament-delineate retaining ligaments of related anatomic structures that have been conceptualized in various ways...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28726106/arginine-derivatives-of-dicarboxylic-acids-from-the-parotid-gland-secretions-of-common-toad-bufo-bufo-new-agonists-of-ionotropic-%C3%AE-aminobutyric-acid-receptors
#3
D S Lebedev, I A Ivanov, E V Kryukova, V G Starkov, V I Tsetlin, Yu N Utkin
Compounds activating γ-aminobutyric acid type A receptor were isolated from the toad Bufo bufo venom as a result of chromatographic separation. Analysis of the structure of these compounds by mass spectrometry and nuclear magnetic resonance showed that they are arginine derivatives of dicarboxylic acids and represent suberylarginine, pimeloylarginine, and adipoylarginine.
May 2017: Doklady. Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28722698/magnetic-resonance-imaging-of-parotid-gland-tumors-dynamic-contrast-enhanced-sequence-evaluation
#4
Xavier Stefanovic, Yassine Al Tabaa, Gregory Gascou, Sandy Lacombe, Yves Auge, Philippe Delort, Paul Hagen, Renaud Garrel, Alain Bonafe, Jean-Pierre Daures, Jean-François Vendrell
OBJECTIVE: The aim of the study was to evaluate dynamic contrast-enhanced magnetic resonance (MR) imaging in the characterization of parotid gland tumors. METHODS: Fifty-five parotid lesions in 55 patients were retrospectively included. Two observers interpreted 2 reading protocols derived from all MR imaging in 2 distinct sessions, independently and blinded. Benign versus malignant distinction was carried out for protocol 1 (without contrast administration) and protocol 2 (with dynamic contrast-enhanced sequence)...
July 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28722506/diffusion-weighted-magnetic-resonance-imaging-of-parotid-glands-before-and-after-abatacept-therapy-in-patients-with-sj%C3%A3-gren-s-syndrome-associated-with-rheumatoid-arthritis-utility-to-evaluate-and-predict-response-to-treatment
#5
Hiroyuki Takahashi, Hiroto Tsuboi, Masahiro Yokosawa, Hiromitsu Asashima, Tomoya Hirota, Yuya Kondo, Isao Matsumoto, Takayuki Sumida
OBJECTIVE: To compare parotid diffusion-weighted images (DWIs) taken before and after abatacept therapy in patients with Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA) and to examine the utility in evaluation and prediction of response to therapy. METHODS: DWIs of the parotid glands taken at baseline and 52 weeks after initiation of abatacept were analyzed in nine SS patients with RA using relative standard deviation (RSD) of the entire glands and signal intensity ratio (SIR) within the residual parenchyma...
July 19, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28721884/dosimetric-predictors-of-patient-reported-xerostomia-and-dysphagia-with-deintensified-chemoradiation-therapy-for-hpv-associated-oropharyngeal-squamous-cell-carcinoma
#6
Bhishamjit S Chera, David Fried, Alex Price, Robert J Amdur, William Mendenhall, Chiray Lu, Shiva Das, Nathan Sheets, Lawrence Marks, Panayiotis Mavroidis
PURPOSE/OBJECTIVE(S): To estimate the association between different dose-volume metrics of the salivary glands and pharyngeal constrictors with patient reported severity of xerostomia/dysphagia in the setting of deintensified chemoradiation therapy (CRT). METHODS AND MATERIALS: Forty-five patients were treated on a phase 2 study assessing the efficacy of deintensified CRT for favorable-risk, HPV-associated oropharyngeal squamous cell carcinoma. Patients received 60 Gy intensity modulated radiation therapy with concurrent weekly cisplatin (30 mg/m(2)), and reported the severity of their xerostomia/dysphagia (before and after treatment) using the patient-reported outcome version of the Common Terminology Criteria for Adverse Events (CTCAE) (PRO-CTCAE)...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28714528/salivary-duct-stenosis-short-term-symptom-outcomes-after-sialendoscopy-assisted-salivary-duct-surgery
#7
Elise A Delagnes, Melissa Zheng, Annick Aubin-Pouliot, Jolie L Chang, William R Ryan
OBJECTIVES: To prospectively assess short-term symptom change after sialendoscopy-assisted salivary duct surgery (SASDS) for salivary duct stenosis. STUDY DESIGN: Prospective cohort study. METHODS: Patients with obstructive sialadenitis from duct stenosis completed the 20-item Chronic Obstructive Sialadenitis Symptoms (COSS) Questionnaire (scored 0-100) prior to SASDS and 3 months postoperatively. RESULTS: Thirty glands in 19 patients with endoscopically confirmed salivary duct stenosis showed overall symptom improvement, with a mean COSS score reduction of 12...
July 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28713751/parotid-duct-repair-with-intubation-tube-technical-note
#8
Muhammed Beşir Öztürk, Seda Asrufoğlu Barutca, Elif Seda Keskin, Bekir Atik
The parotid duct can be damaged in traumatic injuries and surgical interventions. Early diagnosis and treatment of a duct injury is of great importance because complications such as sialocele and salivary gland fistula may develop if the duct is not surgically repaired. We think the cuff of an intubation tube is an ideal material in parotid duct repair, because of its technical characteristics, easiness of availability, and low-cost. In this paper, we described the use of the cuff cannula of an intubation tube for the diagnosis and treatment of parotid duct laceration, as a low-cost and easy to access material readily available in every operating room...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28712533/dose-volume-toxicity-modeling-for-de-intensified-chemo-radiation-therapy-for-hpv-positive-oropharynx-cancer
#9
Panayiotis Mavroidis, Alex Price, David Fried, Mark Kostich, Robert Amdur, William Mendenhall, Chihray Liu, Shiva Das, Lawrence B Marks, Bhishamjit Chera
BACKGROUND AND PURPOSE: The aim is to determine the radiobiological parameters of four popular normal tissue complication probability (NTCP) models that describe the dose-response relations of salivary glands and pharyngeal constrictors to the severity of patient reported xerostomia and dysphagia, respectively 6 and 12months post chemo-radiotherapy, furthermore, to evaluate the goodness-of-fit of the NTCP models for different combinations of glands and constrictors. MATERIAL AND METHODS: Forty-three patients were treated on a prospective multi-institutional phase II study (ClinicalTrials...
July 13, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28710097/germinal-centres-in-diagnostic-labial-gland-biopsies-of-patients-with-primary-sj%C3%A3-gren-s-syndrome-are-not-predictive-for-parotid-malt-lymphoma-development
#10
Erlin A Haacke, Bert van der Vegt, Arjan Vissink, Fred K L Spijkervet, Hendrika Bootsma, Frans G M Kroese
OBJECTIVE: Patients with primary Sjögren's syndrome (pSS) have an increased risk of developing non-Hodgkin's lymphoma (NHL), particularly parotid gland mucosa-associated lymphoid tissue (MALT) lymphomas. Presence of germinal centres (GCs) in labial gland biopsies has been suggested as predictive factor for NHL. We assessed whether presence of GCs is increased in labial gland biopsies from patients with pSS who developed parotid MALT lymphoma, the dominant NHL-subtype in pSS, compared with patients with pSS who did not develop lymphoma...
July 14, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28709532/margins-for-benign-salivary-gland-neoplasms-of-the-head-and-neck
#11
REVIEW
Eric R Carlson, James Michael McCoy
The proper ablation of any neoplasm of the head and neck requires the inclusion of linear and anatomic barrier margins surrounding the neoplasm. Extirpative surgery of the major and minor salivary glands is certainly no exception to this surgical principle. To this end, the selection and execution of the most appropriate ablative surgical procedure for a major or minor benign salivary gland neoplasm is an essential exercise in oral and maxillofacial surgery. Of equal importance is the intraoperative identification and preservation of the pseudocapsule surrounding the benign neoplasm...
August 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/28709482/parotid-tuberculosis
#12
REVIEW
Poras Chaudhary, Bindiya Chaudhary, Chandrakant K Munjewar
Parotid gland tuberculosis is an uncommon manifestation of one of the most common infections even in the developing countries, caused by Mycobacterium tuberculosis. There are no specific symptoms or clinical signs of parotid tuberculosis, and such an infection most commonly presents as a slow growing painless parotid mass. Because of its rarity, tuberculosis of parotid gland is often mistaken for a malignant growth, and it most commonly gets diagnosed after superficial protidectomy. Complete cure is possible with standard antituberculous therapy...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28709149/uptake-of-psma-ligands-in-normal-tissues-is-dependent-on-tumor-load-in-patients-with-prostate-cancer
#13
Florian C Gaertner, Khalil Halabi, Hojjat Ahmadzadehfar, Stefan Kürpig, Elisabeth Eppard, Charalambos Kotsikopoulos, Nikolaos Liakos, Ralph A Bundschuh, Holger Strunk, Markus Essler
Radioligand therapy (RLT) with Lu-177-labeled PSMA-ligands is a new therapy option for prostate cancer. Biodistribution in normal tissues is of interest for therapy planning. We evaluated if the biodistribution of Ga-68-PSMA-11 is influenced by tumor load. RESULTS: In patients with high tumor load, SUVmean was reduced to 61.5% in the lacrimal glands, to 56.6% in the parotid glands, to 63.7% in the submandibular glands, to 61.3% in the sublingual glands and to 55.4% in the kidneys (p < 0...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28708969/a-case-of-early-pneumoparotid-presenting-with-oral-noises
#14
Hiroshi Yamazaki, Rena Kojima, Yasuhiro Nakanishi, Akihiro Kaneko
A 53-year-old man presented with the chief complaint of oral noises. No lesion could be observed in the oral cavity. Ultrasound detected several high-echogenicity areas inside the bilateral parotid ducts, and the initial stage of pneumoparotid was diagnosed. It was considered that air had entered each duct in retrograde fashion through the parotid papilla because of repeated compression of the bilateral parotid glands by the patient who had the habit of compressing the buccal region. This case suggests that ultrasound is effective for diagnosing the initial stage of pneumoparotid...
June 12, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28707990/clinical-usefulness-of-the-mdixon-quant-the-method-for-estimation-of-the-salivary-gland-fat-fraction-comparison-with-mr-spectroscopy
#15
Yoshitaka Kise, Toru Chikui, Yasuo Yamashita, Koji Kobayashi, Kazunori Yoshiura
OBJECTIVES: To estimate the fat fraction (FF) in the salivary glands (SGs) by the mDIXON method and the MRS method, and to compared the results. METHODS: Sixteen healthy volunteers were enrolled. mDIXON Quant and MRS (point-resolved spectroscopy: PRESS) with a single TE were employed to measure the FF in the parotid gland (PG) and submandibular gland (SMG). Multiple TEs were applied in 10 volunteers to correct for T2 decay. In addition, we assumed that the 1.3 ppm peak accounted for 60% of the total fat peak and estimated the FF (MRS all) as a gold standard...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28707954/lymphoepithelial-carcinoma-of-salivary-glands-ct-and-mr-imaging-findings
#16
Pingzhong Wang, Jie Yang, Qiang Yu
OBJECTIVES: To depict the CT and MR imaging characteristics of salivary gland lymphoepithelial carcinoma (LEC) and provide more diagnostic information for this malignancy. METHODS: One hundred and three salivary gland LEC subjects were retrospectively reviewed. The subjects include 35 males with a mean age of 40.8 years and 68 females with a mean age of 49.4 years. Of 103 subjects, 86 subjects were in the parotid gland, five in the submandibular gland, one in the sublingual gland, three in the cheek, and eight in the palate...
July 14, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28707525/is-there-a-role-for-ultrasound-guided-sialoplasty-in-the-management-of-salivary-duct-strictures
#17
Jimmy Makdissi, Lee Feinberg, Amit Roy
Ductal stricture is a common cause of obstructive salivary gland disease. Balloon dilatation of the parotid duct as a minimally invasive technique is currently carried out under fluoroscopic guidance or during sialendocopy. We present a case report of ultrasound guided balloon dilatation. A 45 year old lady presented with a long history of obstructive symptoms affecting the right parotid gland. Ultrasound examination revealed a tortuous right main parotid duct with marked dilatation throughout its course and multiple sites of focal stricture formation...
July 14, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28705814/head-and-neck-mri-findings-in-charge-syndrome
#18
M J Hoch, S H Patel, D Jethanamest, W Win, G M Fatterpekar, J T Roland, M Hagiwara
Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary abnormalities, and Ear abnormalities and deafness (CHARGE) syndrome is a disorder with multiple congenital anomalies seen on imaging. A retrospective review of 10 patients with CHARGE syndrome who underwent MR imaging of the brain as part of a preoperative evaluation for cochlear implantation was conducted. Structural abnormalities of the entire MR imaging of the head were evaluated, including the auditory system, olfactory system, face, skull base, and central nervous system...
July 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28704636/partial-superficial-superficial-and-total-parotidectomy-in-the-management-of-benign-parotid-gland-tumors-a-10-year-prospective-study-of-205-patients
#19
Panagiotis Stathopoulos, Dimosthenis Igoumenakis, William P Smith
PURPOSE: The aim of this report is to present an overview of the authors' experience in treating parotid gland tumors for a period of 10 years. This report describes patients' demographics, surgical outcomes, and complications and discusses the management of benign disease with particular emphasis on the importance of facial nerve dissection. PATIENTS AND METHODS: A total of 205 consecutive patients with different parotid gland tumors underwent surgery at Northampton General Hospital (Northampton, UK) from October 2000 to November 2010...
June 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28697515/-recurrent-sialadenitis-of-both-parotid-glands-in-adolescence
#20
Karolin Weigel, Peggy Rühmer, Michael Borte, Iver Petersen, Martin Scholten, Orlando Guntinas-Lichius
No abstract text is available yet for this article.
June 2017: Laryngo- Rhino- Otologie
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