keyword
https://read.qxmd.com/read/38598351/cardiopulmonary-exercise-testing-in-a-prospective-multicenter-cohort-of-older-adults
#1
JOURNAL ARTICLE
Cody Wolf, Terri L Blackwell, Eileen Johnson, Nancy W Glynn, Barbara Nicklas, Stephen B Kritchevsky, Elvis A Carnero, Peggy M Cawthon, Steven R Cummings, Frederico G S Toledo, Anne B Newman, Daniel E Forman, Bret H Goodpaster
PURPOSE: Cardiorespiratory fitness (CRF) measured by peak oxygen consumption (VO2peak) declines with aging and correlates with mortality and morbidity. Cardiopulmonary Exercise Testing (CPET) is the criterion method to assess CRF, but its feasibility, validity and reliability in older adults is unclear. Our objective was to design and implement a dependable, safe and reliable CPET protocol in older adults. METHODS: VO2peak was measured by CPET, performed using treadmill exercise in 875 adults ≥70 years in the Study of Muscle, Mobility and Aging (SOMMA)...
April 11, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38571126/rer-yolo-improved-method-for-surface-defect-detection-of-aluminum-ingot-alloy-based-on-yolov5
#2
JOURNAL ARTICLE
Ting Chen, Chenguang Cai, Jing Zhang, Yu Dong, Ming Yang, Deguang Wang, Jing Yang, Chengbin Liang
Aluminum ingot alloy is one of the commonly used materials in industrial production and intelligent manufacturing, whose quality directly affects the performance of aluminum processed products. Therefore, the inspection of surface defects of aluminum ingot alloy is extremely valuable for actual industrial engineering. Aiming at the issues of low detecting precision and the slowly processing rate thatexisted in the traditional target detection methods for aluminum ingot alloy dataset, the YOLOv5-based improvement model RER-YOLO is proposed...
March 11, 2024: Optics Express
https://read.qxmd.com/read/38570525/impact-of-a-virtual-reality-based-simulation-training-for-shoulder-dystocia-on-human-and-technical-skills-among-caregivers-a-randomized-controlled-trial
#3
JOURNAL ARTICLE
Veronica Falcone, Anja Catic, Florian Heinzl, Philipp Steinbauer, Michael Wagner, Fanny Mikula, Tim Dorittke, Bernhard Roessler, Alex Farr
This study analyzed the adherence to the modified Advanced Life Support in Obstetrics (ALSO) algorithm (HELP-RER) for handling shoulder dystocia (SD) using a virtual reality (VR) training modality. Secondary outcomes were improvements in the post-training diagnosis-to-delivery time, human skills factors (HuFSHI), and perceived task-load index (TLX). Prospective, case-control, single-blind, 1:1 randomized crossover study. Participants were shown a 360° VR video of SD management. The control group was briefed theoretically...
April 3, 2024: Scientific Reports
https://read.qxmd.com/read/38556075/evaluation-of-a-novel-drilling-approach-for-dynamic-navigation-aided-endodontic-microsurgery-a-surgical-simulation-comparison-study
#4
JOURNAL ARTICLE
Li Qin, Chen Chen, Rui Zhang, Zan Wang, Fangzhe Li, Liuyan Meng
INTRODUCTION: This study investigated the feasibility of a novel drilling approach that integrates a pilot trephine into dynamic navigation (DN) for guided osteotomy and root-end resection (RER) with unimanual operation in endodontic microsurgery (EMS). METHODS: Two operators with varying levels of DN experience performed guided osteotomy and RER using two unimanual drilling methods with DN-aided operation on 3D-printed jaw models. Method 1 (M1) involved drilling with a conventional trephine...
March 29, 2024: Journal of Endodontics
https://read.qxmd.com/read/38555545/a-sponsor-s-perspective-on-the-contribution-of-regulatory-required-observational-post-marketing-studies-to-understanding-human-drug-product-benefit-risk-in-japan
#5
JOURNAL ARTICLE
Kevin D Wolter, Asayuki Kamatani, Yumiko Suzuki, Takayuki Imaeda, Ramzi Dagher, Allan Safferman, Rod Junor
BACKGROUND: Following marketing authorization in Japan, for almost all new drugs or new indications, postmarketing studies (PMS) are a regulatory requirement. These PMS focus on accrual of a defined number of cases with data being collected for a predetermined period after approval to confirm efficacy/effectiveness, safety, and quality in the Japanese population. In contrast to other regions where PMS are only required to address a specific scientific uncertainty, in Japan, PMS are often required regardless of any specific scientific uncertainty, and therefore, their scientific value is unclear...
March 31, 2024: Pharmaceutical Medicine
https://read.qxmd.com/read/38474825/chlorella-supplementation-reduces-blood-lactate-concentration-and-increases-o-2-pulse-during-submaximal-and-maximal-cycling-in-young-healthy-adults
#6
JOURNAL ARTICLE
Harry White, Tom Gurney
Chlorella supplementation is reported to improve V˙O2max following extended supplementation periods (~3 weeks). However, there is little research on its impact over submaximal exercise intensities and following shorter supplementation regimens. This study aimed to investigate the efficacy of 6 g/day 2-day chlorella supplementation on exercise performance in healthy young adults. Twenty young healthy adults (Males = 16, Females = 4) (Age 22 ± 6 years, V˙O2max 42.7 ± 9.6 mL/(kg·min)) were recruited for this double-blinded, randomised cross-over study...
February 29, 2024: Nutrients
https://read.qxmd.com/read/38456897/diagnostic-performance-of-hepatic-ct-and-chemical-shift-mri-to-discriminate-lipid-poor-adrenal-adenomas-from-hepatocellular-carcinoma-metastases
#7
JOURNAL ARTICLE
Yasunori Nagayama, Hidetaka Hayashi, Narumi Taguchi, Ryuya Yoshida, Ryota Harai, Masafumi Kidoh, Seitaro Oda, Takeshi Nakaura, Toshinori Hirai
PURPOSE: To evaluate the diagnostic performance of multiphase hepatic CT parameters (non-contrast attenuation, absolute and relative washout ratios [APW and RPW, respectively], and relative enhancement ratio [RER]) and chemical-shift MRI (CS-MRI) for discriminating lipid-poor adrenal adenomas (with non-contrast CT attenuation > 10 HU) from metastases in patients with hepatocellular carcinoma (HCC). METHODS: This retrospective study included HCC patients with lipid-poor adrenal lesions who underwent multiphase hepatic CT between January 2010 and December 2021...
March 8, 2024: Abdominal Radiology
https://read.qxmd.com/read/38399396/application-of-nir-spectroscopy-for-the-valorisation-of-cork-by-products-a-feasibility-study-over-the-screening-and-discrimination-of-chemical-compounds-of-interest
#8
JOURNAL ARTICLE
Ricardo N M J Páscoa, Cláudia Pinto, Liliana Rego, Joana Rocha E Silva, Maria E Tiritan, Honorina Cidade, Isabel F Almeida
Quercus suber is considered a sustainable tree mainly due to its outer layer (cork) capacity to regenerate after each harvesting cycle. Cork bark is explored for several application; however, its industrial transformation generates a significant amount of waste. Recently, cork by-products have been studied as a supplier of bioactive ingredients. This work aimed to explore whether near infrared spectroscopy (NIRS), a non-destructive analysis, can be employed as a screening device for selecting cork by-products with higher potential for bioactives extraction...
January 30, 2024: Pharmaceuticals
https://read.qxmd.com/read/38398482/long-term-functional-limitations-on-cardiopulmonary-exercise-testing-in-emotion-triggered-takotsubo-syndrome
#9
JOURNAL ARTICLE
Jean Pierre Jabbour, Luca Arcari, Luca Cacciotti, Damiano Magrì, Tommaso Recchioni, Livia Valeri, Enrico Maggio, Carmine Dario Vizza, Roberto Badagliacca, Silvia Papa
Background: In patients with prior Takotsubo syndrome (TTS), long-lasting functional cardiac limitations were described as compared with normal subjects. Emotion-triggered Takotsubo syndrome (E-TTS) has more favorable outcomes than TTS preceded by a physical trigger or by no identifiable factors. The aim of the present study was to assess long-term cardiac functional limitations in a cohort of asymptomatic E-TTS patients. Methods: We enrolled n = 40 asymptomatic patients with a diagnosis of E-TTS. Cardiopulmonary exercise tests (CPET) were performed at 30 (12-40) months median follow-up from the acute event...
February 19, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38308261/introducing-a-novel-intraoral-mandibular-nerve-block-technique-for-loco-regional-analgesia-in-camels-camelus-dromedarius-a-cadaveric-study-using-computed-tomography
#10
JOURNAL ARTICLE
Mohamed Marzok, Mohamed A Nazih, Adel I Almubarak, Zakriya Al Mohamad, Ibrahim A Emam, Mohamed W El-Sherif
The aim of this study was to introduce a novel intraoral technique for performing mandibular nerve blocks in dromedary camels (Camelus dromedarius). In this study, 18 adult camel skulls of varying ages and breeds were examined to determine the position of the mandibular foramen. Using a Vernier caliper, three dimensions in millimeters were measured: (1) the distance between the mandibular foramen (MF) and the caudal edge of the third molar tooth at the occlusal surface level, (2) the distance between the MF and the rostral edge border of the mandible's ramus (RER) at the occlusal surface level, and (3) the distance between the MF and the ventral margin border of the mandible (VM)...
February 3, 2024: BMC Veterinary Research
https://read.qxmd.com/read/38267738/effectiveness-of-a-dose-graded-aerobic-exercise-regimen-on-cardiopulmonary-fitness-and-physical-performance-in-pediatric-survivors-of-acute-lymphoblastic-leukemia-a-randomized-clinical-trial
#11
JOURNAL ARTICLE
Ragab K Elnaggar, Ahmad M Osailan, Mohammed F Elbanna, Amira M Abd-Elmonem
PURPOSE: To determine whether a 12-week supervised dose-graded aerobic exercise (D-GAE) training, when implemented in conjunction with traditional rehabilitation, could help pediatric survivors of acute lymphoblastic leukemia (ALL) enhance their cardiopulmonary capacity and improve their physical performance. METHODS: Fifty-eight pediatric survivors of ALL (age 13.78 ± 2.47 years; boys 60.34%) were assigned at random to either undergo the D-GAE in addition to the traditional physical rehabilitation (D-GAE group; n = 29) or the traditional physical rehabilitation solely (control group; n = 29)...
January 24, 2024: Journal of Cancer Survivorship: Research and Practice
https://read.qxmd.com/read/38263789/assessing-postoperative-motor-risk-in-insular-low-grade-gliomas-patients-the-potential-role-of-presurgery-mri-corticospinal-tract-shape-measures
#12
JOURNAL ARTICLE
Zuo-Cheng Yang, Fang-Cheng Yeh, Bo-Wen Xue, Chuan-Dong Yin, Xin-Yu Song, Gen Li, Zheng-Hai Deng, Sheng-Jun Sun, Zong-Gang Hou, Jian Xie
BACKGROUND: Insular low-grade gliomas (LGGs) are surgically challenging due to their proximity to critical structures like the corticospinal tract (CST). PURPOSE: This study aims to determine if preoperative CST shape metrics correlate with postoperative motor complications in insular LGG patients. STUDY TYPE: Retrospective. POPULATION: 42 patients (mean age 40.26 ± 10.21 years, 25 male) with insular LGGs...
January 23, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38251327/molecular-typing-of-leishmania-spp-causing-tegumentary-leishmaniasis-in-northeastern-italy-2014-2020
#13
JOURNAL ARTICLE
Tommaso Gritti, Elena Carra, Gert Van der Auwera, José Carlos Solana, Valeria Gaspari, Silvana Trincone, Margherita Ortalli, Alice Rabitti, Alessandro Reggiani, Gianluca Rugna, Stefania Varani, The Skin Leish Rer Network
Tegumentary leishmaniasis (TL) is endemic but neglected in southern Europe. Therefore, this study aimed to analyze the Leishmania strains causing TL cases in northeastern Italy, where an upsurge of TL cases has been observed in the last decade. Sections from 109 formalin-fixed and paraffin-embedded (FFPE) biopsies of skin and mucosal tissues were collected from TL cases in the selected area. Two DNA targets were amplified and sequenced: the ribosomal internal transcribed spacer 1 (ITS1) and the heat-shock protein 70 gene (hsp70)...
December 24, 2023: Pathogens
https://read.qxmd.com/read/38197606/acute-effects-of-commercial-energy-drink-consumption-on-exercise-performance-and-cardiovascular-safety-a-randomized-double-blind-placebo-controlled-crossover-trial
#14
RANDOMIZED CONTROLLED TRIAL
Nile F Banks, Emily M Rogers, Nate J Helwig, Laura E Schwager, Justin P Alpers, Sydni L Schulte, Emma R Trachta, Christopher M Lockwood, Nathaniel D M Jenkins
The aim of this study was to examine the acute effects of a non-caloric energy drink (C4E) compared to a traditional sugar-containing energy drink (MED) and non-caloric placebo (PLA) on exercise performance and cardiovascular safety. Thirty healthy, physically active males (25 ± 4 y) completed three experimental visits under semi-fasted conditions (5-10 h) and in randomized order, during which they consumed C4E, MED, or PLA matched for volume, appearance, taste, and mouthfeel. One hour after drink consumption, participants completed a maximal, graded exercise test (GXT) with measurement of pulmonary gases, an isometric leg extension fatigue test (ISOFTG ), and had their cardiac electrical activity (ECG), leg blood flow (LBF), and blood pressure (BP) measured throughout the visit...
December 2024: Journal of the International Society of Sports Nutrition
https://read.qxmd.com/read/38190376/exercise-training-independent-of-intensity-lowers-plasma-bile-acids-in-prediabetes
#15
JOURNAL ARTICLE
Steven K Malin, U S Afsheen Syeda
INTRODUCTION: People with obesity have high circulating bile acids (BA). Although aerobic fitness favors low circulating BAs, the effect of training intensity prior to clinically meaningful weight loss on BA is unclear. Test the hypothesis that 2-wks of interval (INT) versus continuous (CONT) exercise would lower plasma BAs in relation to insulin sensitivity. METHODS: Twenty-three older adults with prediabetes (ADA criteria) were randomized to 12 work-matched bouts of INT (n = 11; 60...
January 8, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38137757/predictors-of-long-covid-and-chronic-impairment-of-exercise-tolerance-in-spiroergometry-in-patients-after-15-months-of-covid-19-recovery
#16
JOURNAL ARTICLE
Katarzyna Gryglewska-Wawrzak, Agata Sakowicz, Maciej Banach, Agata Bielecka-Dabrowa
BACKGROUND: The aim of the study was to identify factors that may cause the presence of long COVID and to assess factors that affect chronic limited exercise tolerance in spiroergometry after one-year follow-up in patients who had recovered from COVID-19. METHODS: Of 146 patients hospitalised in the Cardiology Department, 82 completed a one-year follow-up (at least 15 months post-COVID-19 recovery). We compared their conditions at initial screening and follow-up to analyse the course of long COVID and exercise intolerance mechanisms...
December 14, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38137239/a-novel-variable-selection-method-based-on-ordered-predictors-selection-and-successive-projections-algorithm-for-predicting-gastrodin-content-in-fresh-gastrodia-elata-using-fourier-transform-near-infrared-spectroscopy-and-chemometrics
#17
JOURNAL ARTICLE
Zhenjie Wang, Changzhou Zuo, Min Chen, Jin Song, Kang Tu, Weijie Lan, Chunyang Li, Leiqing Pan
Gastrodin is one of the most important biologically active components of Gastrodia elata , which has many health benefits as a dietary and health food supplement. However, gastrodin measurement traditionally relies on laboratory and sophisticated instruments. This research was aimed at developing a rapid and non-destructive method based on Fourier transform near infrared (FT-NIR) to predict gastrodin content in fresh Gastrodia elata . Auto-ordered predictors selection (autoOPS) and successive projections algorithm (SPA) were applied to select the most informative variables related to gastrodin content...
December 11, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38125488/assessing-the-differences-of-two-vineyards-soils-by-nir-spectroscopy-and-chemometrics
#18
JOURNAL ARTICLE
Sandia Machado, Luisa Barreiros, António R Graça, Manuel Madeira, Ricardo N M J Páscoa, Marcela A Segundo, João A Lopes
Soil properties influence greatly the status of vine plants which consequently influences the quality of wine. Therefore, in the context of viticulture management, it is extremely important to assess the physical and chemical parameters of vineyards soils. In this study, the soils of two vineyards were analysed by near-infrared (NIR) spectroscopy and established analytical reference procedures. The main objective of this study was to verify if NIR spectroscopy is a potential tool to discriminate the soils of both vineyards as well as to quantify differences of soil's parameters...
December 2023: Heliyon
https://read.qxmd.com/read/38114986/comparison-of-energy-expenditure-measurements-by-a-new-basic-respiratory-room-vs-classical-ventilated-hood
#19
JOURNAL ARTICLE
Timia Van Soom, Wiebren Tjalma, Ulrike Van Daele, Nick Gebruers, Eric van Breda
BACKGROUND: Nutritional support is often based on predicted resting energy expenditure (REE). In patients, predictions seem invalid. Indirect calorimetry is the gold standard for measuring EE. For assessments over longer periods (up to days), room calorimeters are used. Their design makes their use cumbersome, and warrants improvements to increase utility. Current study aims to compare data on momentary EE, obtained by a basic respiration room vs. classical ventilated hood. The objective is to compare results of the basic room and to determine its 1) reliability for measuring EE and 2) sensitivity for minute changes in activity...
December 20, 2023: Nutrition Journal
https://read.qxmd.com/read/38109660/does-the-menstrual-cycle-influence-aerobic-capacity-in-endurance-trained-women
#20
JOURNAL ARTICLE
Sofie Ekberg, Bente Morseth, Karin B Larsén, Lisbeth Wikström-Frisén
Purpose: The aim was to study if aerobic capacity varies during different phases of the menstrual cycle (MC) in endurance-trained female athletes. Methods: Ten endurance-trained eumenorrheic women performed a submaximal test followed by an incremental test until exhaustion three times during one MC, early follicular phase (EFP), late follicular phase (LFP), and midluteal phase (MLP). During the submaximal test, the respiratory exchange ratio (RER) and utilization of fat and carbohydrates were analyzed; and, during the incremental test, VO2 peak , maximal heart rate, utilization of fat and carbohydrates, and RER were analyzed...
December 18, 2023: Research Quarterly for Exercise and Sport
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