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pigmented villonodular synovitis

Yaxia Zhang, Michael Joyce, Jean Schils, Thomas W Bauer
Sarcoidosis is a systemic inflammatory disorder characterized by non-caseating granulomas, predominantly involving lung, mediastinal lymph nodes and other organs. Synovium involvement is infrequent, and as far as we know, involvement of a periprosthetic membrane has not been reported in the English literature. Intra-articular diffuse tenosynovial giant cell tumor ("conventional diffuse pigmented villonodular synovitis") is an uncommon, locally aggressive neoplasm with few previous case reports in which it arose in periprosthetic tissues after knee arthroplasty...
October 7, 2016: Skeletal Radiology
Qian-Qian Gao, Yuan-Yong Feng, Ling-Xue Bu, Kai Song, Xin Dai, Wei Shang
Pigmented villonodular synovitis (PVNS) is a benign, proliferative disorder of synovium. It often affects the knee, and rarely occurs in the temporomandibular joint (TMJ). This paper reported a 45-year-old male patient with PVNS of the TMJ, who was referred with a chief complaint of slowly growing and painless preauricular mass that was noticed about 1 year. Radical excision and follow-up were conducted, no recurrence and metastasis were noted.
June 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Rajendra Kumar, Robert A Lefkowitz, Afranio Dos Reis Teixeira Neto
OBJECTIVE: This retrospective study was undertaken to highlight clinical and magnetic resonance imaging features of myxoinflammatory fibroblastic sarcoma. METHODS: The clinical records of 29 patients (14 men and 15 women) were analyzed. RESULTS: The soft tissue tumors involved hand, wrist, foot and ankle in 21 patients, more proximal extremities in 7 patients, and neck in 1 patient. The tumors were subcutaneous in 11 patients, and intramuscular in 15 patients...
August 25, 2016: Journal of Computer Assisted Tomography
Liang Zhao, Kaiyu Zhou, Yimin Hua, Yifei Li, Dezhi Mu
INTRODUCTION: Pigmented villonodular synovitis (PVNS) is a rare, benign proliferative disorder of the synovial membrane that typically presents in adults and affects a single joint. Multifocal PVNS is very rare, particularly in childhood. We reported a rare case of multifocal PVNS affecting over 20 joints in a child. CLINICAL PROCEDURE: A 7-year-old female patient had a 6-month history of multifocal joints swelling with mild pain. She was diagnosed as polyarticular juvenile idiopathic arthritis at a local hospital...
August 2016: Medicine (Baltimore)
Marlon Araujo Ramos, Niso Eduardo Balsini, Fernando Ramos, Luiz Gustavo Machado
This case concerns a male patient complaining of pain and discomfort in his right elbow, associated with decreased range of motion. Elbow radiography showed an osteolytic lesion in the metaphyseal region of the distal humerus and magnetic resonance imaging showed intra-articular tumor formation with swelling that suggested pigmented villonodular synovitis. Arthroscopic treatment was performed in order to obtain a synovial biopsy and then to carry out total synovectomy. Anatomopathological examination confirmed the diagnosis...
July 2016: Revista Brasileira de Ortopedia
Stephen R Stephan, Brandon Shallop, Richard Lackman, Tae Won B Kim, Mary K Mulcahey
No abstract text is available yet for this article.
July 19, 2016: JBJS Rev
Michalis Mazonakis, Antonis Tzedakis, Efrossyni Lyraraki, John Damilakis
Pigmented villonodular synovitis (PVNS) is a benign disease affecting synovial membranes of young and middle-aged adults. The aggressive treatment of this disorder often involves external-beam irradiation. This study was motivated by the lack of data relating to the radiation exposure of healthy tissues and radiotherapy-induced cancer risk. Monte Carlo methodology was employed to simulate a patient's irradiation for PVNS in the knee and hip joints with a 6 MV photon beam. The average radiation dose received by twenty-two out-of-field critical organs of the human body was calculated...
September 7, 2016: Physics in Medicine and Biology
Ashley Startzman, Devin Collins, Dominic Carreira
OBJECTIVES: Benign synovial diseases of the hip including Synovial Chondromatosis (SC) and Pigmented Villonodular Synovitis (PVNS) are devastating diseases. Initially, patients present with hip pain unrelieved by conservative measures. The diagnosis of PVNS and SC are often delayed, leading to progression of joint damage. The purpose of this review is to present the latest on the diagnosis, management, and prognosis of SC and PVNS of the hip. METHODS: An extensive systematic search of MEDLINE and PUBMED Databases was performed...
July 22, 2016: Physician and Sportsmedicine
Victoria H Wilkinson, Emma L Rowbotham, Andrew J Grainger
The foot and ankle are commonly involved in a range of arthritides that affect the joints, bones, and soft tissues. Accurate plain film interpretation can often aid the diagnosis and monitor disease progression and treatment response. Ultrasound and MRI afford superior depiction of the soft tissues, and advances over recent years have centered on early detection of synovitis, enabling earlier diagnosis and treatment. Advantages and disadvantages of the imaging techniques of radiography, multidetector computed tomography, ultrasound, and MRI are discussed, as is optimization of these modalities for the assessment of the anatomically complex joints of the foot and ankle...
April 2016: Seminars in Musculoskeletal Radiology
Cheung Man Hong, Lui Tun Hing
INTRODUCTION: Pigmented villonodular synovitis (PVNS) is a proliferative condition of the synovium, which is composed of nodules and/or villi and has an abundant number of hemosiderin-laden macrophages. CASE REPORT: A 10-year-old boy presented with an acute irritable knee. Emergency arthroscopy showed a nodular PVNS in the intercondylar notch. The symptoms resolved after resection of the lesion. CONCLUSION: PVNS of the knee in children is a rare entity...
July 2015: Journal of Orthopaedic Case Reports
Nikhil Gokhale, Shaligam Purohit, Pradeep B Bhosale
INTRODUCTION: Pigmented villonodular synovitis is an uncommon disease characterized by hyperplastic synovium, large effusions and bone erosions. It commonly mimics other conditions. As a result, the diagnosis may remain elusive, as the classic signs of tenderness and effusion are not specific. Occasionally, PVNS presents as a popliteal cyst, which may divert attention from intra-articular pathology. In this article, we describe a case of pigmented villonodular synovitis that presented with a popliteal cyst as the chief problem...
July 2015: Journal of Orthopaedic Case Reports
Valerio Belgrano, Ilan Ben-Shabat, Peter Bergh, Roger Olofsson Bagge
BACKGROUND: Isolated limb perfusion (ILP) is an established and effective treatment for advanced melanoma and soft tissue sarcomas of the extremities with a high overall response rate. The aim of this study was to describe our experience of ILP for more rare types of tumours. METHODS: Patients with Merkel cell carcinoma (MCC) (n = 4), squamous cell carcinoma (SCC) (n = 2), B-cell lymphoma (n = 1), desmoid tumours (n = 3), pigmented villonodular synovitis (PVNS) (n = 1) and giant cell tumour (n = 1) were treated with ILP and analysed retrospectively...
September 2016: International Journal of Hyperthermia
Abdellatif Benabbouha, Jonathan Basinga, Ismail Anteri, Abdelouab Jaafar
Pigmented villonodular synovitis (PVNS) is a rare pseudotumoral proliferative benign condition of unknown etiology, affecting synovial joints. It can also develop in the synovial bursae and in the tendon sheaths. It usually affects large joints, such as the knee and the hip. Ankle is a rare location, with only a few cases reported in the literature. We report a case of a 52 year old patient with a PVS of the right ankle. She received a subtotal synovectomy. After 2 years of follow-up there was no clinical recurrence...
2016: Pan African Medical Journal
Kiersten Pianosi, Matthew Rigby, Robert Hart, Jonathan Trites, S Mark Taylor
Pigmented villonodular synovitis (PVNS) is a rare and benign proliferative disorder of synovium with potentially locally aggressive growth and invasion of the bone. Occurring within the joints, tendon sheaths, and bursae, it is most commonly a monoarticular disease affecting large joints. In particular, most cases of PVNS occur in the knee. PVNS of the temporomandibular joint (TMJ) is a highly rare disorder, with approximately 60 cases reported. Herein, we present a unique case of an elderly male presenting with ear pain and subsequently diagnosed with PVNS of the TMJ with a history of trauma to the area...
April 2016: Plastic and Reconstructive Surgery. Global Open
Comfort O Elumogo, James N Kochenderfer, A Cahid Civelek, David A Bluemke
Pigmented villonodular synovitis (PVNS) is a benign joint disease best characterized on magnetic resonance imaging (MRI). The role of fluorine 18 fluorodeoxyglucose ((18)F-FDG) position emission tomography-computed tomography (PET-CT) in the diagnosis or characterization remains unclear. PVNS displays as a focal FDG avid lesion, which can masquerade as a metastatic lesion, on PET-CET. We present a case of PVNS found on surveillance imaging of a lymphoma patient.
April 2016: Quantitative Imaging in Medicine and Surgery
Lizz van der Heijden, Sheila R Piner, Michiel Adrianus Josephus van de Sande
PURPOSE: We aimed to ascertain the feasibility of crowdsourcing via Facebook for medical research purposes; by investigating surgical, oncological and functional outcome and quality-of-life (QOL) in patients with pigmented villonodular synovitis (PVNS) enrolled in a Facebook community (1112 members). METHODS: Patients completed online open surveys on demographics, surgery and clinical outcomes (group 1); and patient-reported outcome measures (PROMs) including knee-injury osteoarthritis outcome score (KOOS), hip-disability osteoarthritis outcome score (HOOS), Toronto extremity salvage score (TESS) and SF-36 (group 2)...
May 12, 2016: International Orthopaedics
Javier Martin-Broto, Nadia Hindi
PURPOSE OF REVIEW: Sarcoma is a heterogeneous group of malignancies historically treated with classic cytotoxic chemotherapy. This review updates the recent advances in targeted therapies in soft-tissue sarcoma, bone sarcoma and other connective diseases with local aggressiveness. RECENT FINDINGS: Platelet-derived growth factor receptor (PDGFR) inhibitors, antiangiogenics, cell cycle inhibitors and immunomodulatory agents are the main targeted therapies in development in sarcoma...
July 2016: Current Opinion in Oncology
Tahsin Beyzadeoğlu, Esra Çirci
We report a 24-year-old male who was admitted to the emergency department with an unusual complaint of locked hip joint. Magnetic resonance imaging (MRI) showed a 3-cm intra-articular synovial nodular mass and a 3.0x2.4x1.6-cm yellow-brownish colored pediculed synovial nodular mass was excised with hip arthroscopy. Pathological examination confirmed the diagnosis of pigmented villonodular synovitis. Excision of the mass allowed prompt resolution of the symptoms and there was no sign of recurrence at 3-year follow-up...
2016: Acta Orthopaedica et Traumatologica Turcica
Xinning Li, Phillip Williams, Emily J Curry, Jo A Hannafin
Two elite female athletes presented with anterior knee pain with range of motion and reproducible tenderness to palpation. Diagnostic arthroscopy was performed in both cases resulting in excision of a nodular pigmented villonodular synovitis (PVNS) in the first patient and scar tissue in the second patient. Correct diagnosis of anterior knee pain in the elite female athlete can present a challenge to clinicians. Although patellofe-moral pain is the most common diagnosis, other uncommon causes include PVNS and residual scar formation in patients with a history of surgery or trauma...
March 21, 2016: Orthopedic Reviews
Bharat Rekhi, Anuj Verma, Nirmala A Jambhekar, Santosh Menon, Siddhartha Laskar, Nikhil Merchant, Neha Mittal, Ajay Puri
Epithelioid sarcoma (ES) displays a wide clinicopathologic spectrum. On histopathology, osteoclast-like giant cells have been rarely described in these tumors. A 45-year-old gentleman presented with a perineal swelling of 6-month duration. Radiologic imaging disclosed a large, highly vascular tumor mass in his perineal region that was diagnosed elsewhere as pigmented villonodular synovitis. A 58-year-old lady presented with a recurrent tumor in her right inguinolabial region for which she underwent multiple tumor resections in the past...
April 2016: Annals of Diagnostic Pathology
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