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pigmented villonodular synovitis

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https://www.readbyqxmd.com/read/29220303/locally-aggressive-connective-tissue-tumors
#1
Mrinal M Gounder, David M Thomas, William D Tap
In this review, we highlight the complexities of the natural history, biology, and clinical management of three intermediate connective tissue tumors: desmoid tumor (DT) or aggressive fibromatosis, tenosynovial giant cell tumor (TGCT) or diffuse-type pigmented villonodular synovitis (dtPVNS), and giant cell tumor of bone (GCTB). Intermediate histologies include tumors of both soft tissue and bone origin and are locally aggressive and rarely metastatic. Some common aspects to these tumors are that they can be locally infiltrative and/or impinge on critical organs, which leads to disfigurement, pain, loss of function and mobility, neurovascular compromise, and occasionally life-threatening consequences, such as mesenteric, bowel, ureteral, and/or bladder obstruction...
December 8, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29215692/chondroid-tenosynovial-giant-cell-tumor-of-the-temporomandibular-joint-a-rare-case-report
#2
Ana Lia Anbinder, Barbara Maria Corrêa Geraldo, Rubens Guimarães, Débora Lima Pereira, Oslei Paes de Almeida, Yasmin Rodarte Carvalho
Tenosynovial giant cell tumor of diffuse type (TGCT-d) or pigmented villonodular synovitis (PVNS) is a locally aggressive lesion that mostly affects the joints of long bones. Chondroid tenosynovial giant cell tumor (CTGCT) or PVNS with chondroid metaplasia is a rare distinct subset of synovial tumors that has a predilection for the TMJ. We report a rare case of CTGCT in the TMJ, initially misdiagnosed as temporomandibular disorder (TMD). A 51-year-old woman was referred to the surgeon with the chief complaint of TMJ pain for 5 years and a past history of an unsuccessful TMD treatment...
September 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29202997/arthroscopic-treatment-of-intra-artricularly-localised-pigmented-villonodular-synovitis-of-the-ankle-4-cases-with-long-term-follow-up
#3
Ulunay Kanatli, M Baybars Ataoğlu, Mustafa Özer, Ahmet Yildirim, Mehmet Cetinkaya
BACKGROUND CONTEXT: Pigmented villonodular synovitis (PVNS) is a rare, locally aggressive benign proliferative pathology of synovial tissue. Lesions are classified regarding location as diffuse or localised which are same as histologically. Intra-articularly localised type is relatively rare, especially in the ankle joint. Because of the high recurrence rate and aggressive nature, localised lesions should be excised totally. PURPOSE: We performed a retrospective study of 4 patients with intra-articularly localised PVNS in the ankle joint who were treated by total arthroscopic excision and evaluated for functional results and recurrence rate...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29137617/surgical-treatment-for-diffused-type-giant-cell-tumor-pigmented-villonodular-synovitis-about-the-ankle-joint
#4
Xingchen Li, Yang Xu, Yuan Zhu, Xiangyang Xu
BACKGROUND: Diffused-type giant cell tumor(Dt-GCT) is a rare, aggressive disorder of the joint synovium, bursa and tendon sheaths. Osseous erosions and subchondral cysts may develop as the result of synovium infiltration in Dt-GCT. We present a retrospective study of a series of patients who are diagnosed with Dt-GCT about the ankle joint, there clinical outcome is evaluated in this study. MATERIAL AND METHOD: Fifteen patients with radiologically and histologically confirmed Dt-GCT about the ankle joint were identified in our foot and ankle department...
November 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29062829/total-knee-replacement-in-patients-with-diffuse-villonodular-synovitis
#5
Lucio Flávio Biondi Pinheiro Junior, Marcos Henrique Frauendorf Cenni, Rafael Henriques Soares Leal, Luiz Eduardo Moreira Teixeira
This paper reports a case of diffuse pigmented villonodular synovitis (DPVNS), associated with advanced gonarthrosis, submitted to total knee replacement. The patient had progressive pain and swelling. She had two previous surgeries, firstly arthroscopic synovectomy and subsequently open synovectomy associated with radiotherapy, with recurrence of the disease. Magnetic resonance imaging revealed diffuse synovitis, advanced arthrosis, and bone cysts. The patient was submitted to a total knee replacement and synovectomy...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28978573/a-rare-case-of-localised-pigmented-villonodular-synovitis-in-the-knee-of-a-24-year-old-female-soccer-player-diagnosis-management-and-summary-of-tenosynovial-giant-cell-tumours
#6
Casper Falster, Simon Stockmann Poulsen, Uffe Joergensen
Localised pigmented villonodular synovitis (PVNS) of the knee is a rare diagnosis, with clinical signs and symptoms mimicking meniscal damage or other common knee injuries.We report the case of a 24-year-old female soccer player, seeking treatment after 7 months of persisting knee pain. Additionally, we present an overview of tenosynovial giant cell tumours.On examination, the patient was found to have tenderness in the medial joint space of the knee. MRI revealed a heterogeneous formation in the central part of the knee...
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28884104/diffuse-pigmented-villonodular-synovitis-in-knee-joint-diagnosis-and-treatment
#7
Eduardo Frois Temponi, Antônio Augusto Guimarães Barros, Vinícius Oliveira Paganini, Victor Atsushi Kasuya Barbosa, Roger Badet, Lúcio Honório de Carvalho Júnior
Pigmented villonodular synovitis is a rare proliferative condition of the synovium. Although the condition can present in any joint, the knee is the most commonly affected site. Despite being a benign condition, pigmented villonodular synovitis is often aggressive, with marked extra-articular extension in some cases. Monoarticular involvement occurs in two forms: localized and diffuse. The latter is more common, with a high recurrence rate. There is no standard method of management of this lesion. Open surgery is a classical and effective method for treatment...
June 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28875266/csf-1r-inhibitor-development-current-clinical-status
#8
REVIEW
Florent Peyraud, Sophie Cousin, Antoine Italiano
PURPOSE OF REVIEW: Colony-stimulating factor 1 receptor (CSF-1R) and its ligands, CSF-1 and interleukin 34 (IL-34), regulate the function and survival of tumor-associated macrophages, which are involved in tumorigenesis and in the suppression of antitumor immunity. Moreover, the CSF-1R/CSF-1 axis has been implicated in the pathogenesis of pigmented villonodular synovitis (PVNS), a benign tumor of the synovium. As advanced or metastatic malignant solid tumors and relapsed/refractory PVNS remain unresolved therapeutic problems, new approaches are needed to improve the outcome of patients with these conditions...
September 5, 2017: Current Oncology Reports
https://www.readbyqxmd.com/read/28864387/tenosynovial-giant-cell-tumor-in-the-midfoot-treated-with-femoral-head-allograft-reconstruction
#9
Daniel J Fuchs, Paul J Switaj, Terrance D Peabody, Anish R Kadakia
Tenosynovial giant cell tumor (also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis) is a rare soft tissue tumor that arises from the tenosynovium of a tendon sheath or the synovium of a diarthrodial joint. This disease process occurs infrequently in the foot and ankle but can result in significant bone erosion and destructive changes of affected joints. These cases are challenging to treat, because the tumor most commonly presents in young, active patients and can be associated with extensive bone loss...
August 29, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28776631/diffuse-pigmented-villonodular-synovitis-as-a-rare-cause-of-graft-failure-following-anterior-cruciate-ligament-reconstruction
#10
Rajiv Rajani, Liliana Ogden, Christopher J Matthews, C Parker Gibbs
This case report describes a 42-year-old woman who was diagnosed with pigmented villonodular synovitis (PVNS) in the knee. The patient had received a bone-patella tendon-bone autograft reconstruction of her anterior cruciate ligament (ACL) 22 years prior to her diagnosis of PVNS. After a traumatic event that tore her ACL graft, she underwent a second surgery to repair the initial reconstruction. However, her pain and joint instability remained unresolved. When radiolucent lesions in her tibia and femur were identified through a radiographic image, the patient was referred to the authors' orthopedic oncology clinic...
August 3, 2017: Orthopedics
https://www.readbyqxmd.com/read/28764182/pigmented-villonodular-synovitis-of-thumb-a-cytological-diagnosis
#11
Kaneeka Bhatnagar, Akshdeep Singh Bawa, Vikram Narang, Pavneet Kaur
Pigmented Villonodular Synovitis (PVNS) is a unique benign proliferative process of unknown aetiology involving the synovial lined joints diffusely or focally. The entity remains a diagnostic challenge. This condition is attributed to an increased synovial proliferation causing villous or nodular changes of synovial lined joints leading to PVNS, Pigmented Villonodular Bursitis (PVNB) when arising from bursae or Pigmented Villonodular Tenosynovitis (PVNTS) originating from the tendon sheath. We present a case of a young female with nodular masses on right thumb with cytomorphological features on FNAC suggestive of PVNS which was finally confirmed by histopathology...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28749260/pigmented-villonodular-synovitis-in-a-reticulated-giraffe-giraffa-camelopardalis
#12
Elizabeth A Ihms, Anne Rivas, Ellen Bronson, Lisa M Mangus
: A 17-yr-old, female, captive-born reticulated giraffe ( Giraffa camelopardalis ) presented with acute-onset lameness of the right metacarpophalangeal (fetlock) joint. Despite multiple courses of treatment, the lameness and swelling progressively worsened over a 3.5-yr period, and the giraffe was euthanized. At necropsy, gross and microscopic changes in the right, front fetlock and associated flexor tendon sheath included villous synovial hyperplasia and the formation of discrete pigmented nodules within synovial membranes...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28728303/-enhancing-soft-tissue-reattachment-with-artificial-mesh-in-joint-endoprosthetic-reconstruction-for-bone-tumors
#13
J S Lin, R Chen, W Yan, D D Chen
Objective: To investigate the operative method and clinical application of the BARD(®) Mesh in enhancing joint stability and function of endoprosthetic reconstruction for bone tumors. Methods: From Jan 2013 to Jun 2015, the clinical data of 51 patients aged (44.75±23.18) years underwent wide resection of tumor and endoprosthetic reconstruction using the BARD(®) Mesh were collected. Among them, 27 were male and 24 were female. The surgical treatments received by these patients included 5 shoulder arthroplasties, 12 elbow replacements, 12 hip replacements and 32 knee replacements (including 24 femoral tumors and 8 tibial tumors)...
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28685013/arthroscopic-approach-for-treating-a-pigmented-villonodular-sinovitis-of-tmj-a-case-report
#14
Maria Roman-Ramos, Paolo Cariati, Almudena Cabello-Serrano, Miguel Garcia-Martin, Blas Garcia-Medina
The present report describes the case of a 29-year-old man referred to our service for TMJ pain and progressive reduction of the mouth opening. Differential diagnostics included rheumatologic diseases, monoarthritis and intraarticular lumps. In this line, a face CT scan and a MRI of TMJ were carried out in order to ensure a proper diagnosis. These tests showed a solid lesion into the joint cavity. In view of that, we decided to perform a diagnostic and therapeutic arthroscopy of TMJ. Histopathological studies confirmed the diagnosis of pigmented villonodular synovitis...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28683727/multifocal-pigmented-villonodular-synovitis-coexisting-in-both-the-knee-joint-and-the-patella-a-case-report-and-literature-review
#15
Mingxuan Gao, Hong Li, Xiaoyan Liang, Xiaoyan Fu, Xusheng Li
BACKGROUD: Pigmented villonodular synovitis (PVNS) is an uncommon entity of proliferative lesion of the synovium, presenting with different clinical signs and symptoms. PVNS rarely forms an osteolytic lesion in a bone. Here we report a unique case of PVNS with a nodular lesion in the left patella. CASE PRESENTATION: A 37-year-old female was referred to our hospital with complaints of ongoing left knee pain and a painful and palpable mass in her left popliteal fossa...
July 6, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28652100/current-role-for-radioisotope-synovectomy
#16
Vincent André, Vincent Dalibard, Emmanuelle Dernis, Stéphane Varin, Grégoire Cormier
Radioisotope synovectomy has been extensively used to treat patients with chronic inflammatory joint disease but has moved to a less prominent position since the introduction of new and highly effective drugs. Remaining indications are refractory synovitis, pigmented villonodular synovitis as an adjunct to surgery, and hemophilic arthropathy. The three main radioisotopes used are yttrium-90, rhenium-186, and erbium-189. Radioisotope synovectomy should be performed only by highly experienced professionals, to minimize the risk of injection-related complications...
June 23, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28638690/an-unusual-case-of-diffuse-pigmented-villonodular-synovitis-of-the-shoulder-a-multidisciplinary-approach-with-arthroscopic-synovectomy-and-adjuvant-radiotherapy
#17
Tânia Quinás Serra, João Morais, Zico Gonçalves, Francisco Agostinho, Gilberto Melo, Mónica Henriques
Pigmented villonodular synovitis (PVNS) is a rare proliferative disorder of the synovial membrane. This condition is usually monoarticular, can be locally destructive, and involves muscles, tendons, bursae, bones, and skin. The most commonly affected joints are the knee and hip, followed by the ankle and shoulder. Patients often present with pain, swelling, and joint effusion; however, the duration of symptoms varies. Total synovectomy is the preferred treatment for PVNS. Subtotal synovectomy is a factor of recurrence, and in diffuse PVNS, total excision is very difficult to achieve...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28552192/long-term-outcome-of-knee-arthroplasty-in-the-setting-of-pigmented-villonodular-synovitis
#18
Matthew T Houdek, Maurizio Scorianz, Cody C Wyles, Robert T Trousdale, Franklin H Sim, Michael J Taunton
BACKGROUND: Pigmented villonodular synovitis (PVNS) is a rare, benign proliferation of the synovium, commonly affecting the knee. Arthroplasty can successfully manage arthrosis in this population; however, outcome data is limited. The purpose of this study was to investigate the oncologic and functional outcome of patients undergoing total knee arthroplasty (TKA) in the setting of PVNS. METHODS: 48 patients were identified at our institution with histologically confirmed PVNS that subsequently received TKA...
May 25, 2017: Knee
https://www.readbyqxmd.com/read/28461957/pigmented-villonodular-synovitis-of-the-hip
#19
Sylvain Steinmetz, Anne-Laure Rougemont, Robin Peter
Pigmented villonodular synovitis (PVNS) is a rare disease that can affect any joint, bursa or tendon sheath.The hip is less frequently affected than the knee, and hence is less discussed in scientific journals.PVNS of the hip mainly occurs in young adults, requiring early diagnosis and adequate treatment to obtain good results.There is no consensus on the management of PVNS of the hip in current literature.We will discuss the options for surgical intervention in hip PVNS using a literature review of clinical, biological, etiological, histological and radiographic aspects of the disease...
June 2016: EFORT Open Reviews
https://www.readbyqxmd.com/read/28447110/-diagnosis-and-therapy-of-benign-intraarticular-tumors
#20
REVIEW
H R Dürr, A Klein
Intraarticular benign tumors are rare lesions in many cases seen as incidental findings. One of the typical lesions is the diffuse or nodular form of pigmented villonodular synovitis, which needs a complete surgical removal. Magnetic Resonance Imaging (MRI) is diagnostic in most of the cases because of the intracellular iron content which shows an at least in some parts dark T2-sequence. Adjuvant therapies as radiosynoviorthesis should be considered in diffuse or recurrent lesions. Synovial Chondromatosis represents a metaplastic disorder of the synovial membrane resulting in the production of loose cartilage bodies...
June 2017: Der Orthopäde
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