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https://www.readbyqxmd.com/read/29026829/aggressive-combined-medical-and-surgical-management-of-mucormycosis-results-in-disease-eradication-in-2-pediatric-patients
#1
Haley F M Augustine, Colin White, James Bain
Rhinocerebral mucormycosis is an acute, rapidly fatal, fungal infection, classically involving the nasal mucosa and paranasal sinuses. It is an aggressive, opportunistic infection that frequently progresses to involve the orbit and cerebrum. Cerebral extension in immunocompromised patients is almost universally fatal. There are limited data on mucormycosis in pediatric immunocompromised patients in the literature, with only few reports on rhinocerebral involvement. The immunocompromised patients described in this report presented with suspected periorbital and nasal cellulitis, progressing rapidly to necrotic changes in nasal tissue and oral palatal mucosa...
August 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29025178/-reconstructive-urethral-surgery
#2
Vahudin Zugor, Daniel Porres, Leonidas Karapanos, Axel Heidenreich, Ilgar Akbarov
Urethral strictures are independent of a patient's age and can happen in every life period. They are often iatrogenic, resulting from a transurethral surgical procedure or traumatic catheterisation. Endoscopic slotting is the surgery of choice; although this method is frequently associated with recurrence. Retrograde urethrography or cystourethrography continue to play a central role in diagnostic evaluation and treatment. There is no standardised procedure regarding the surgical technique, perioperative management, and postoperative follow-up...
October 12, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/29019875/anterograde-injection-of-low-dose-urokinase-salvages-free-anterolateral-thigh-flap-a-case-report-of-safe-and-effective-treatment
#3
Shao-Yun Hsu, Hsu-Tang Cheng, Oscar Manrique, Yung-Chang Hsu
RATIONALE: A 54-year-old Taiwanese male came to our hospital presented with right retromolar mucoepidermoid carcinoma. Composite resection and right modified radical neck dissection were performed. We then use free anteral lateral thigh flap to reconstruct the defect. However, venous congestion was found 32 h after the surgery. PATIENT CONCERNS: The main concerns of the patient is complete salvage of the free flap, and avoiding the secondary free flap harvesting and reconstruction surgeries...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29016574/microvascular-free-flaps-in-oral-and-maxillofacial-reconstruction-following-cancer-ablation
#4
Santosh Kumar Yadav, Suraksha Shrestha
Microsurgical free flaps have become the first choice for reconstruction of oral and maxillofacial (OMF) defects after tumor resection. Till recently the pectoralis major myocutaneous flap (PMMC) was considered to be the benchmark for OMF reconstruction. This philosophy is changing fast with rapid advancement in reconstructive microsurgery. Years of innovation in reconstructive microsurgery has given us a reasonably good number of excellent flaps. Tremendous work has been put into producing some exceptionally brilliant research articles, sometimes contradicting each other...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28990694/suprafascial-versus-traditional-harvesting-technique-for-free-antero-lateral-thigh-flap-a-case-control-study-to-assess-the-best-functional-and-aesthetic-result-in-extremity-reconstruction
#5
Michele Maruccia, Nefer Fallico, Emanuele Cigna, Pedro Ciudad, Fabio Nicoli, Emilio Trignano, Eleonora Nacchiero, Giuseppe Giudice, Diego Ribuffo, Hung-Chi Chen
Clinical applications of ALT flap have currently extended to extremity (hand and foot) as well as oral cavity reconstruction. In these anatomical areas, the traditional harvesting technique presents a few disadvantages such as bulkiness of the recipient site and potential donor site morbidity including damage to the deep fascia and skin graft adhesions. The purpose of the present study was to compare the functional and aesthetic outcomes of upper and lower extremity reconstruction with either suprafascial or subfascial harvested anterolateral (ALT) flaps...
October 9, 2017: Microsurgery
https://www.readbyqxmd.com/read/28989544/local-therapies-for-breast-cancer
#6
REVIEW
Ruth Exner
During the San Antonio Breast Cancer Symposium in December 2016, the main topics were systemic treatment of breast cancer and molecular research. But several studies were also presented concerning local therapy: Surgical issues on evaluating resection margins, management of ductal carcinoma in situ (DCIS), surgical challenges after neoadjuvant therapy related to assessment of response or treatment of axillary lymph nodes, and studies about outcome after breast reconstruction and radiation therapy were discussed...
2017: Memo
https://www.readbyqxmd.com/read/28987224/controversies-in-traditional-oral-and-maxillofacial-reconstruction
#7
REVIEW
John S Vorrasi, Antonia Kolokythas
Traditional reconstruction of the head and neck and significantly evolved over the last 20 to 30 years with advances in microvascular surgery, biologic materials such as bone morphogenic protein, and dental implant predictability. Earlier and more definitive reconstruction can now be achieved with combining therapies, allowing patients immediate restoration of function and improved cosmetics. Antiresorptive medications, such as Denosumab and bisphosphonates, have complicated bony reconstruction treatments with altered biology and less-predictable results...
November 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/28968919/nutritional-aspects-of-enhanced-recovery-after-esophagectomy-with-gastric-conduit-reconstruction
#8
REVIEW
B Feike Kingma, Elles Steenhagen, Jelle P Ruurda, Richard van Hillegersberg
Enhanced Recovery After Surgery (ERAS) aims to accelerate recovery by a set of multimodality management strategies. For esophagectomy, several nutritional elements of ERAS can be safely introduced and are advised in routine practice, including preadmission counseling to screen and treat for potential malnutrition, shortened preoperative fasting, and carbohydrate loading. However, the timing of oral intake and the use of routine nasogastric decompression remain matter of debate after esophagectomy. Furthermore, more research is needed on future developments such as perioperative immunonutrition...
October 2, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28963817/comparison-of-outcomes-with-extensive-segmental-pectoralis-major-myocutaneous-flap-via-the-anterior-axillary-line-and-the-conventional-technique-in-oral-and-oropharyngeal-cancer
#9
Wei-Liang Chen, Da-Ming Zhang, Zhi-Quan Huang, Yan Wang, Bin Zhou, You-Yuan Wang
BACKGROUND: This study compared the outcomes of an extensive segmental pectoralis major myocutaneous flap (esPMMF) and a conventional pectoralis major myocutaneous flap (PMMF). METHODS: The study enrolled 91 patients with primary oral and oropharyngeal squamous cell carcinoma (SCC) who underwent radical resection followed by reconstruction of the defect using either an esPMMF via the anterior axillary line or a PMMF. The pedicle lengths of the esPMMF and PMMF were 22-28 and 18-22 cm, respectively...
September 30, 2017: Head & Neck
https://www.readbyqxmd.com/read/28961098/ieee-international-symposium-on-biomedical-imaging
#10
(no author information available yet)
The IEEE International Symposium on Biomedical Imaging (ISBI) is a scientific conference dedicated to mathematical, algorithmic, and computational aspects of biological and biomedical imaging, across all scales of observation. It fosters knowledge transfer among different imaging communities and contributes to an integrative approach to biomedical imaging. ISBI is a joint initiative from the IEEE Signal Processing Society (SPS) and the IEEE Engineering in Medicine and Biology Society (EMBS). The 2018 meeting will include tutorials, and a scientific program composed of plenary talks, invited special sessions, challenges, as well as oral and poster presentations of peer-reviewed papers...
September 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28960881/interspecies-dynamics-among-bacteria-associated-with-canine-periodontal-disease
#11
P Sanguansermsri, A H Nobbs, H F Jenkinson, R Surarit
The etiology and pathogenic mechanisms associated with canine periodontal disease are less well understood than the disease in humans. In this study we have reconstructed defined consortia biofilms in vitro of microorganisms identified as prevalent in a same-breed cohort of dogs with or without periodontal disease. Frederiksenia canicola and Neisseria canis were selected as potential early colonizers of salivary pellicle, and Fusobacterium nucleatum and Porphyromonas gulae were included as high incidence canine oral bacteria...
September 28, 2017: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/28960470/three-dimensional-reconstruction-with-serial-whole-mount-sections-of-oral-tongue-squamous-cell-carcinoma-a-preliminary-study
#12
Yujia Wang, Sheng Chen, Yanhong Ni, Derek Magee, Yumei Pu, Qian Zhou, Zhiyong Wang, Lei Zhang, Xiaofeng Huang, Qingang Hu
OBJECTIVES: Margin status and invasion pattern are prognostic factors for oral tongue squamous cell carcinoma (OTSCC). Current methods to identify these factors are limited to 2D observation, it is necessary to explore 3D reconstruction with whole-mount sample to improve analysis accuracy. This study aimed to study the tissue-preparation, section generation and 3D reconstruction with whole-mount OTSCC specimen. STUDY DESIGN: Two OTSCC samples were retrieved from Nanjing Stomatological Hospital, Medical School of Nanjing University...
September 28, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28955004/successful-treatment-of-mixed-mainly-cancer-pain-by-tramadol-preparations
#13
Shinji Kawahito, Tomohiro Soga, Naoji Mita, Shiho Satomi, Hiroyuki Kinoshita, Tomoko Arase, Akira Kondo, Hitoshi Miki, Kazumi Takaishi, Hiroshi Kitahata
The patient, a 70-year-old Japanese woman diagnosed with parotid gland cancer, underwent wide excision and reconstruction (facial nerve ablation, nerve transposition). At 1 month after the surgery, she was brought to our hospital's pain medicine department because her postoperative pain and cancer-related pain were poorly controlled. She had already been prescribed a tramadol (37.5 mg)/acetaminophen (325 mg) combination tablet (5 tablets/day). However, in addition to the continuous pain in her face and lower limbs, she was troubled by a trigeminal neuralgia-like prominence ache...
2017: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/28953734/the-horizontal-myocutaneous-infrahyoid-island-flap-for-soft-tissue-head-and-oral-reconstruction-step-by-step-video-description
#14
Charlie Verbruggen, Claire Majoufre, Laure Derosamel, Pierre-Antoine Dubreuil, Gabrielle Vallade, Caroline Mage, Quentin Sessiecq, Mathieu Bondaz
A clinical case is presented of a 70-year-old woman suffering from a right hemilingual epidermoid carcinoma. A step-by-step video description of the regional infrahyoid island flap is presented and narrated. Long-term results at 2 months in terms of aesthetics and function at the recipient and donor sites are excellent. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, V.
October 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28953155/bilateral-submental-flap-an-innovative-modification
#15
Kiran Gadre, Pushkar Gadre, Divya Singh, Anushri Shetty, Ankit Malu
Early management of premalignant lesions like oral submucous fibrosis cannot be underestimated in context of prevention and control of oral malignancies. Soft tissue reconstruction of the oral cavity and face is a complex undertaking. Several flaps local and distant as well as microvascular are available, each with their pros and cons. Microvascular free flaps lay a considerable burden on resources, expertise, increased operating time, and logistics. Simple and technically reproducible alternatives are needed to tackle these issues, more so in developing countries like ours...
September 25, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28953152/secondary-maxillary-and-orbital-floor-reconstruction-with-a-free-scapular-flap-using-cutting-and-fixation-guides-created-by-computer-aided-design-computer-aided-manufacturing
#16
Daiki Morita, Toshiaki Numajiri, Shoko Tsujiko, Hiroko Nakamura, Ryo Yamochi, Yoshihiro Sowa, Makoto Yasuda, Shigeru Hirano
Computer-aided design/computer-aided manufacturing (CAD/CAM) guides are now widely used in maxillofacial reconstruction. However, there are few reports of CAD/CAM guides being used for scapular flaps. The authors performed the secondary maxillary and orbital floor reconstruction using a free latissimus dorsi muscle, cutaneous tissue, and scapular flap designed using CAD/CAM techniques in a 72-year-old man who had undergone partial maxillectomy four years previously. The patient had diplopia, the vertical dystopia of eye position, and a large oral-nasal-cutaneous fistula...
September 25, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28947696/-surgical-treatment-for-anti-resorptive-agents-related-osteonecrosis-of-jaw
#17
Yoshihide Ota
The mechanisms of ARONJ(anti-resorptive agents-related osteonecrosis of jaw)are not completely known. Therefore the treatment policy has been controversial between surgical and conservative approach. Recently, surgical treatment, particularly in stage 2 and 3 cases, has been increasingly reported in literature and is considered a success when oral mucosa healing is maintained without bone exposure or infection. The surgical treatment modalities were classified as follows:debridement, sequestrectomy, marginal resection(bone resection without bone defect), bone reconstruction(free flaps)...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28944821/transplantation-of-periodontal-ligament-cell-sheets-expressing-human-%C3%AE-%C3%A2-defensin%C3%A2-3-promotes-anti%C3%A2-inflammation-in-a-canine-model-of-periodontitis
#18
Minwen Zhu, Bo Miao, Jianhua Zhu, Haiyan Wang, Zengtong Zhou
Periodontitis is a chronic oral inflammatory disease caused by microorganisms. Human β‑defensin‑3 (HBD‑3) is an endogenous antimicrobial peptide that inhibits a broad spectrum of microorganisms. Cell sheet technology has been widely applied in tissue and organ reconstructions. In the current study, it was aimed to investigate the anti‑inflammatory effect of periodontal tissue engineered by HBD‑3 gene‑modified periodontal ligament cell (PDLC) sheets, and to identify a suitable method of promoting the regeneration of periodontal tissues...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944220/determinants-for-further-wishes-for-cosmetic-and-reconstructive-interventions-in-1652-patients-with-surgical-treated-carcinomas-of-the-oral-cavity
#19
Henrik Holtmann, Simon Spalthoff, Nils-Claudius Gellrich, Jörg Handschel, Julian Lommen, Norbert R Kübler, Gertrud Krüskemper, Majeed Rana, Karoline Sander
BACKGROUND: The impairment of the appearance is a major problem for patients with carcinomas of the oral cavity. These patients want to recover their preoperative facial appearance. Some do not realize that this is not always possible and hence develop a desire for further cosmetic and reconstructive surgery (CRS) which often causes psychological problems. METHOD: The desire of patients for CRS (N = 410; 26%) has been acquired in this DÖSAK rehab study including multiple reasons such as medical, functional, aesthetic and psychosocial aspects...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28943022/patient-reported-quality-of-life-outcomes-following-treatment-for-oral-cancer
#20
J Breeze, A Rennie, D Dawson, J Tipper, K-U Rehman, N Grew, N Pigadas
Patient-reported quality of life (QoL) outcomes have the potential to assist clinicians in providing individually tailored treatment decisions. QoL assessments were collected prospectively for 168 consecutive patients treated for oral cancer between 1 January 2010 and 31 December 2014 using the University of Washington Quality of Life Questionnaire. Patients were followed up for 18 months post-treatment. Sub-group analyses were performed using paired t-tests and analysis of variance (ANOVA) to compare the effects of adjunctive chemoradiotherapy, type of bone resection, and methods of soft and hard tissue flap reconstruction...
September 21, 2017: International Journal of Oral and Maxillofacial Surgery
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