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Orbital lymphoma

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https://www.readbyqxmd.com/read/28421369/immunophenotypic-profiles-for-distinguishing-orbital-mucosa-associated-lymphoid-tissue-lymphoma-from-benign-lymphoproliferative-tumors
#1
Shunichiro Ueda, Yoshihiko Usui, Takeshi Nagai, Daniel Diaz-Aguilar, Toshitaka Nagao, Hiroshi Goto
PURPOSE: To evaluate novel immunophenotypic profiles of patients with orbital lymphoproliferative tumors. METHODS: From 2006 to 2014, surgical biopsies from consecutive patients with newly diagnosed orbital mucosa-associated lymphoid tissue (MALT) lymphoma and IgG4-related ophthalmic disease (IgG4-ROD) were collected from Tokyo Medical University Hospital. A total of 44 tumors from 44 patients were analyzed, including 21 with orbital MALT lymphoma (11 men and 10 women, mean age 67...
April 18, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28416234/orbit-lymphomas-in-spanish-population-descriptive-study-and-side-effects-of-treatment-with-radiotherapy
#2
Pilar Cifuentes-Canorea, Maravillas Abia-Serrano, Nuria Ibáñez-Flores
No abstract text is available yet for this article.
April 14, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28399347/conjunctival-tumors-review-of-clinical-features-risks-biomarkers-and-outcomes-the-2017-j-donald-m-gass-lecture
#3
Carol L Shields, Jason L Chien, Thamolwan Surakiatchanukul, Kareem Sioufi, Sara E Lally, Jerry A Shields
Conjunctival tumors encompass a broad range of diagnoses. The 3 most important malignant tumors include ocular surface squamous neoplasia (OSSN) (14%), melanoma (12%), and lymphoma (7%). Conjunctival malignancies are rarely found in children. Regarding OSSN, pre-disposing conditions include chronic solar radiation, immune deficiency (HIV), organ transplant, autoimmune conditions, xeroderma pigmentosum, and chronic exposure to cigarette smoke. OSSN is managed surgically or with topical/injection immunotherapy or chemotherapy...
March 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28399341/lymphoproliferative-tumors-of-the-ocular-adnexa
#4
Robert M Verdijk
The ocular adnexa include the eyelids, conjunctiva, lacrimal apparatus, and orbital soft tissue. One percent of all lymphomas and approximately 8% of all extranodal lymphomas arise in the ocular adnexa and their incidence is increasing. Reactive lymphoid hyperplasia comprises 16% of all lymphoproliferative tumors of the ocular adnexa. The relative frequencies of ocular adnexal lymphoma presentation are in the orbit, 37%; conjunctiva, 29%; lacrimal apparatus, 20%; and eyelid, 14%. The most frequent primary lymphoma types of the ocular adnexa are extranodal marginal zone lymphoma, 62%; follicular lymphoma, 17%; and diffuse large B-cell lymphoma, 10%...
March 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28399335/recent-advances-in-orbital-tumors-a-review-of-publications-from-2014-2016
#5
Santosh G Honavar, Fairooz P Manjandavida
The aim of this review article is to provide an update of the current literature on orbital tumors. The authors conducted a PubMed literature search of English language articles published between January 2014 and December 2016 using the following search items: orbit, tumors, lacrimal gland, lymphoma, hemangioma, lymphangioma. The authors included reviews, original articles, case series, and case reports with relevant new information. There is new information about the clinical spectrum of orbital tumors, capillary hemangioma, cavernous hemangioma, lymphangioma, orbital venous malformation, lacrimal gland tumors, and orbital lymphoma...
March 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28389894/upper-fornix-approach-combined-with-a-superior-lateral-cantholysis-a-minimally-invasive-approach-to-the-superonasal-intraconal-space
#6
Ho-Seok Sa, Ji Won Seo, Sunah Kang
PURPOSE: To present a new minimally invasive approach to the deep superonasal orbit. METHODS: This retrospective study reviewed seven consecutive patients who underwent orbital surgery using an upper conjunctival fornix approach combined with a superior lateral cantholysis for tumors in the superonasal intraconal space. Charts were reviewed for demographic, radiological, clinical, and surgical data including surgical outcome and morbidities for each patient. RESULTS: Six benign tumors of the superonasal intraconal orbit were successfully exposed and removed using this approach, and one malignant tumor was biopsied for diagnosis...
April 7, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28380647/-low-dose-radiotherapy-in-primary-marginal-zone-lymphoma-of-the-orbit
#7
K Zahiti-Rashiti, Y Ruiz, E Graeff, P Meyer
No abstract text is available yet for this article.
April 5, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28372859/the-wedge-sign-an-imaging-sign-for-aggressive-lacrimal-gland-disease
#8
Daniele Lorenzano, Geoffrey E Rose
PURPOSE: Lacrimal gland carcinoma can form a triangle of tissue back to the orbital apex, intraconal spread apparently being prevented by the intermuscular septum. The "wedge sign" frequency is assessed in lacrimal carcinoma, lacrimal lymphoma, or dacryoadenitis. DESIGN: Retrospective masked review of images from patients with biopsy-proven lacrimal gland pathology. METHODS: For each patient, the presence of a triangle of tissue between the lateral rectus and lateral orbital wall and the superior rectus and the orbital roof was assessed by masked review of computed tomography or magnetic resonance imaging...
March 31, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28370694/ultra-low-dose-radiotherapy-for-definitive-management-of-ocular-adnexal-b-cell-lymphoma
#9
Chelsea C Pinnix, Bouthaina S Dabaja, Sarah A Milgrom, Grace L Smith, Zeinab Abou, Loretta Nastoupil, Jorge Romaguera, Francesco Turturro, Nathan Fowler, Luis Fayad, Jason Westin, Sattva Neelapu, Michelle A Fanale, Maria A Rodriguez, Frederick Hagemeister, Hun Ju Lee, Yasuhiro Oki, Michael Wang, Felipe Samaniego, Linda Chi, Bita Esmaeli
BACKGROUND: The purpose of this study was to report the response to and toxicity of ultra-low-dose radiotherapy (RT) for B-cell ocular adnexal lymphoma (OAL). METHODS: We conducted a retrospective review of patients with indolent B-cell and mantle cell OAL treated with 4 Gy to the orbit(s) in two 2-Gy fractions. Disease response was assessed clinically and/or radiographically at 2 to 4-month intervals after RT. Data collected included rates of overall response, complete response (CR), partial response (PR), and treatment-related toxic effects...
April 3, 2017: Head & Neck
https://www.readbyqxmd.com/read/28367175/analysis-of-orbital-malignancies-presenting-in-a-tertiary-care-hospital-in-pakistan
#10
Asad Aslam Khan, Suhail Sarwar, Mohammad Ali A Sadiq, Imran Ahmad, Nayab Tariq, Sibghat-Ul-Noor
OBJECTIVE: To determine the frequencies of various orbital malignancies amongst orbital lesions in patients presenting in a tertiary care hospital in Pakistan. METHODS: A retrospective analysis of 666 orbital cases with an established histopathological diagnosis of malignant tumors treated in Mayo Hospital Lahore from 1996 to 2015 (20 years). RESULTS: About 66% of the malignant tumors were primary, 25% secondary, 8% haematopoietic and 1% metastatic...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28367047/incipient-ocular-mucosa-associated-lymphoid-tissue-lymphoma-in-igg4-related-orbital-disease
#11
Ji Won Kim, Sol Ah Han, Byeong Jae Son, Myoung Ju Koh, Jin Sook Yoon
No abstract text is available yet for this article.
April 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28364339/characteristics-of-orbital-lymphoma-a-clinicopathological-study-of-26-cases
#12
Daniel Briscoe, Christine Safieh, Yokrat Ton, Hava Shapiro, Ehud I Assia, Dvora Kidron
OBJECTIVE: Evaluation of the medical data of patients with orbital and adnexal lymphoma. DESIGN: Cohort study of all cases diagnosed with orbital or adnexal lymphoma at Meir Medical Center between 1993 and 2007. PARTICIPANTS: Twenty-six patients, with intraorbital or subconjunctival masses with orbital involvement, were examined and followed up between 1 and 8 years. MATERIALS AND METHODS: Examined data included: clinical presentation, age, gender, imaging, tumor location, surgical management, and pathological diagnosis...
March 31, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28348632/primary-ocular-adnexal-extranodal-marginal-zone-mucosa-associated-lymphoid-tissue-malt-lymphoma-presenting-as-orbital-apex-syndrome
#13
Carlen A Yuen, John H Pula, Milap Mehta
A 75-year-old female with a past medical history significant for prior stroke and atrial fibrillation presented with acute onset of orbital apex syndrome with chemosis and periorbital ecchymosis. Following initial treatment to relieve intraocular pressure, she began spontaneously haemorrhaging retro-orbitally. Preliminary investigation with neuroimaging demonstrated a left orbital mass with extension into the orbital apex. A provisional diagnosis of cavernous haemangioma was made. She was treated with transorbital resection of the orbital mass...
April 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28346259/igg4-related-ophthalmic-disease-presenting-as-choroidal-and-orbital-lesions
#14
William S Gange, Stephen M Holland, Felipe De Alba
PURPOSE: To report a case of IgG4-related ophthalmic disease (IgG4-ROD) which presented as choroidal and orbital lesions. METHODS: Case report. RESULTS: A 64-year-old man presented with left eye photopsias and a history of IgG4-related perirenal fibrosis. Fundoscopic examination showed multiple bilateral yellow choroidal lesions, and optical coherence tomography showed multiple choroidal lesions. Magnetic resonance imaging of the orbits showed an enhancing lesion present circumferential to the optic nerve, but greater medially, abutting the posterior surface of the left globe...
March 24, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28331132/orbital-malt-lymphoma-after-autologous-stem-cell-transplantation-for-follicular-lymphoma-as-relapse-of-diffuse-large-b-cell-lymphoma
#15
Toshihiko Matsuo, Takehiro Tanaka, Nobuharu Fujii
We report a patient who developed orbital MALT lymphoma after autologous peripheral blood stem cell transplantation for follicular lymphoma as relapse of diffuse large B-cell lymphoma. A 54-year-old woman with systemic lymphadenopathy was diagnosed with diffuse large B-cell lymphoma by left supraclavicular lymph node biopsy, and underwent 6 courses of R-CHOP chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, leading to complete response. Five years later in the follow-up, an abdominal mass with abnormal uptake was found by whole-body 2-[(18)F]fluoro-2-deoxy-D-glucose positron emission tomography, and computed tomography-guided biopsy demonstrated follicular lymphoma...
2017: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/28328558/dacryoadenitis-as-the-initial-presentation-of-a-natural-killer-t-cell-lymphoma
#16
Juan C Jiménez-Pérez, Frederick A Jakobiec, Fouad R Zakka, Michael K Yoon
Primary orbital natural killer T-cell lymphoma (NKTCL) is a rare condition with only a few published cases in the literature. Over 1 month, an 81-year-old man developed progressive left periocular inflammation unresponsive to treatment. Clinical examination and imaging studies demonstrated a left lacrimal gland enlargement. Bilateral anterior uveitis and erythematous nontender cutaneous lesions were also found. Biopsies of the skin and lacrimal gland on the back revealed histopathologic and immunohistochemical findings confirming Epstein-Barr virus-positive NKTCL...
March 21, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28284742/local-disease-control-in-ocular-adnexal-lymphoproliferative-disorders-comparative-outcomes-of-malt-versus-non-malt-histologies
#17
Binod Dhakal, Timothy S Fenske, Sridevi Ramalingam, Jamie Shuff, Narendranath Epperla, Paul Hosking, Lisa Rein, Anjisnu Banerjee, Parameswaran Hari, Anita D'Souza, Nirav Shah, Malika Siker, Gregory J Griepentrog, Gerald J Harris, Timothy S Wells, Beth A Erickson, Mehdi Hamadani
INTRODUCTION: Ocular adnexal lymphoproliferative disorders (OALDs) are almost exclusively of B-cell origin, with the majority being extra-nodal marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT). The comparative efficacy of involved field radiation therapy (IFRT) in MALT vs. non-MALT OALDs is not known. MATERIALS AND METHODS: We present a single-center, large cohort, retrospective study of the efficacy of IFRT in OALDs. Failure-free survival (FFS), complete remission, and local, regional, and distant failure were determined for 112 patients with MALT OALDs (n = 71) and non-MALT OALDs (n = 41) cohorts...
February 16, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28275603/isolated-extranodal-natural-killer-t-cell-lymphoma-of-the-orbit-in-a-young-patient-complete-regression-with-the-smile-regimen
#18
Rachna Meel, Rebika Dhiman, Meenakshi Wadhwani, Seema Kashyap, Sanjay Sharma, Ajay Gogia
PURPOSE: Natural killer T-cell lymphoma (NKTL) is a highly malignant tumor that typically arises in the nose and/or paranasal sinuses. Isolated orbital involvement by NKTL is extremely rare, and only few case reports exist in the literature. Herein, we report a case of primary orbital NKTL in a young patient who showed very good response to chemotherapy with the SMILE regimen. METHODS: A 28-year-old healthy female presented to us with epiphora and fullness of the lower eyelid...
January 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/28217141/primary-orbital-mantle-cell-lymphoma-flow-cytometric-immunophenotyping-as-an-adjunct-to-fine-needle-aspiration-cytology-for-diagnosis
#19
Sangeeta Verma, Nalini Gupta, Satyawati Mohindra, Manupdesh Singh Sachdeva, Arvind Rajwanshi
No abstract text is available yet for this article.
2017: CytoJournal
https://www.readbyqxmd.com/read/28194321/extranodal-natural-killer-t-cell-lymphoma-presenting-as-orbital-cellulitis
#20
Hanis Zuhaimy, Hayati Abdul Aziz, Suresh Vasudevan, Siah Hui Hui
Objective: To report an aggressive case of extranodal natural killer/T-cell lymphoma (NKTCL) of the ethmoid sinus presenting as orbital cellulitis Method: Case report Results: A 56-year-old male presented with right eye redness, reduced vision, and periorbital swelling for 5 weeks duration associated with a two-month history of blocked nose. The visual acuity of the right eye was 6/18. The eye was proptosed with periorbital oedema and conjunctival chemosis. The pupil was mid-dilated but there was no relative afferent pupillary defect...
2017: GMS Ophthalmology Cases
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