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Orbital lymphoma

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https://www.readbyqxmd.com/read/27911447/the-enlarged-extraocular-muscle-to-relax-reflect-or-refer
#1
F Shafi, P Mathewson, P Mehta, H S Ahluwalia
PurposeExtraocular muscle enlargement (EOME) is most commonly associated with thyroid eye disease, but there are other causes. We report our outcomes of investigating and managing non-thyroid-related EOME (NTR-EOME).MethodsRetrospective consecutive case series. Sixteen patients identified by clinical features and orbital imaging. Patient demographics, radiological features, and adjuvant tests including biopsy and final diagnosis were recorded.ResultsMean age at presentation 59.3 years (range 24-89 years). Mean follow-up 3...
December 2, 2016: Eye
https://www.readbyqxmd.com/read/27900092/primary-orbital-precursor-t-cell-lymphoblastic-lymphoma-report-of-a-unique-case
#2
Lisa Stenman, Marta Persson, Fredrik Enlund, Erik Clasen-Linde, Göran Stenman, Steffen Heegaard
Primary T-cell lymphoblastic lymphoma (T-LBL) in the eye region is very rare. The present study described a unique case of T-LBL involving the extraocular muscles. A 22-year-old male patient presented with a 3-week history of headache, reduced visual acuity and edema of the left eye. Clinical examination revealed left-sided exophthalmus, periorbital edema, chemosis, and reduced motility of the left eye. A magnetic resonance imaging scan revealed thickening of the left orbital muscles and a positron emission tomography-computed tomography scan also demonstrated activity in a subclavicular lymph node...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27894519/proptosis-as-initial-manifestation-of-burkitt-s-lymphoma-with-orbital-involvement
#3
A de Freytas, M Rengel Ruiz, E España Gregori
CASE PRESENTATION: A 35-year-old woman without any known systemic disorder presented with a complaint of painful and rapidly increasing proptosis in her right eye. Based on the clinical, radiological, analytical and ophthalmological assessments, the diagnosis made was Burkitt's lymphoma in acquired immunodeficiency syndrome. CONCLUSION: Proptosis can be an unusual way of presenting with Burkitt's lymphoma associated with acquired immunodeficiency. This differential diagnosis is important because confirmation leads to a change in the vital prognosis of the patient...
November 25, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27882744/transpalpebral-exenteration-in-cattle-a-retrospective-study-of-115-cases
#4
Munashe Chigerwe, John A Angelos, Lisa Gamsjäeger, Meera C Heller
OBJECTIVE: To describe the indications for exenteration and complications associated with the procedure. ANIMALS STUDIED: 115 cattle. PROCEDURES: Medical records of cattle presented for unilateral exenteration evaluated at the University of California, Davis Veterinary Medical Teaching Hospital from January 1985 through December 2015 were reviewed. RESULTS: Median (range) age at presentation for all cattle was 6 (0.2-30) years...
November 24, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27824517/a-rare-case-of-orbital-hodgkin-lymphoma-demonstrating-therapeutic-response-to-a-novel-systemic-medication
#5
Brynn N Wajda, Michael P Rabinowitz
Orbital Hodgkin lymphoma is infrequent, representing less than 1% of adult orbital malignancies. It is typically seen in the setting of terminally advanced systemic disease. This case highlights orbital, head, and neck disease in a systemically stable individual treated with the novel anti-CD30 monoclonal antibody brentuximab vedotin.
November 8, 2016: Orbit
https://www.readbyqxmd.com/read/27818811/first-report-of-aids-related-burkitt-s-lymphoma-presenting-as-bilateral-orbital-masses
#6
Monica Alves de Almeida, Juliana Nesi Cardoso Migliano Porto, Ana Carolina de Brito Lyra, Luiz Arthur Calheiros Leite, Rodrigo Panno Basilio-de-Oliveira, Rogério Neves-Motta, Andréa Ramos Correa, Fernando Raphael de Almeida Ferry, Walter de Araujo Eyer-Silva, Ronaldo Grechi Pacheco
Burkitt's lymphoma (BL) is an aggressive B-cell non-Hodgkin's lymphoma and one of the fastest growing tumors in humans. It is an acquired immunodeficiency syndrome- (AIDS-) defining disease and occurs with relatively preserved CD4 cell counts. It rarely affects the orbital region in the setting of AIDS. We report unusual presentation of a fatal case of AIDS-associated BL in a 42-year-old female patient with severe CD4 cell depletion who presented with dramatic fast growing (within days) bilateral orbital masses leading to striking facial deformities...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27789481/long-term-course-of-patients-with-primary-ocular-adnexal-malt-lymphoma-a-large-single-institution-cohort-study
#7
Amrita Desai, Madhura G Joag, Lazaros Lekakis, Jennifer R Chapman, Francisco Vega, Robert Tibshirani, David Tse, Arnold Markoe, Izidore S Lossos
While Primary Ocular Adnexal MALT Lymphoma (POAML) is the most common orbital tumor, there are large gaps in knowledge of its natural history. We conducted a retrospective analysis of the largest reported cohort, consisting of 182 patients with POAML, diagnosed or treated at our institution to analyze long-term outcome, response to treatment, incidence and localization of relapse and transformation. The majority of patients (80%) presented with stage I disease. Overall, 84% of treated patients achieved a complete response after first-line therapy...
October 27, 2016: Blood
https://www.readbyqxmd.com/read/27740876/natural-killer-t-cell-lymphoma-of-the-orbit-an-evidence-based-approach
#8
Juan C Jiménez-Pérez, Michael K Yoon
Natural killer T-cell lymphoma (NKTCL) is a rare and aggressive condition with a high mortality rate. It is most commonly seen in the nasal sinuses, generally affecting the orbit by direct extension. Primary orbital NKTCL is even more rare, with only a few published cases with occasional secondary nasal involvement. This malignancy can present as a "masquerade syndrome," delaying proper diagnosis and treatment. Biopsy is required for diagnosis, which shows specific histopathological characteristics. Radiation and chemotherapy are the mainstay of treatment...
October 14, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27674830/acute-and-late-toxicity-of-bilateral-orbital-irradiation-in-the-management-of-primary-intraocular-lymphoma
#9
S A Milgrom, C Cheah, C C Pinnix, G L Smith, B Dabaja, P Horace, P Chevez-Barrios, N H Fowler, D S Gombos
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27649521/lymphoma-and-inflammation-in-the-orbit-diagnostic-performance-with-diffusion-weighted-imaging-and-dynamic-contrast-enhanced-mri
#10
Bo Sun, Liyuan Song, Xinyan Wang, Jing Li, Junfang Xian, Feifei Wang, Pan Tan
PURPOSE: To investigate the diagnostic performance of diffusion-weighted imaging (DWI), dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), and the combination of both in the differential diagnosis of lymphoma and inflammation in the orbit. MATERIALS AND METHODS: This retrospective study was approved by the Institutional Review Board and the informed consent requirement was waived. A total of 53 patients underwent preoperative 3T MRI. Parameters of DWI and DCE MRI were evaluated in these 30 patients with orbital lymphoma and 23 patients with orbital inflammation...
September 20, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27644607/clinicopathologic-assessment-of-ocular-adnexal-lymphoproliferative-lesions-at-a-tertiary-eye-hospital-in-iran
#11
Fahimeh Asadi-Amoli, Zohreh Nozarian, Hirbod Nasiri Bonaki, Vahid Mehrtash, Samaneh Entezari
BACKGROUND: The most common type of ocular lymphoma is non-Hodgkin lymphoma (NHL), categorized into two groups: indolent (slow growing) and aggressive (rapid growing). Differentiating benign reactive lymphoid hyperplasia (RLH) from malignant ocular adnexal lymphoma (OAL) is challenging. Histopathology, immunohistochemistry (IHC) and ow cytometry have been used as diagnostic tools in such cases. MATERIALS AND METHODS: In this retrospective case series, from 2002 to 2013 at Farabi Eye Center, 110 patients with ocular lymphoproliferative disease were enrolled...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27631251/gallium-spect-ct-in-evaluation-of-igg4-related-disease-a-case-report-and-literature-review
#12
Tzyy-Ling Chuang, Bao-Bao Hsu, Chen-Lin Chi, Yuh-Feng Wang
BACKGROUND: The clinical picture of IgG4-related sclerosing disease (IgG4-RSD) may mimic lymphoma, and should be in the differential diagnosis of patients with this clinical picture. CASE SUMMARY: A 32-year-old female had recurrent swelling of both eyelids for more than 15 years. Examination revealed elastic, firm, swollen lacrimal glands about 2-3 cm in diameter that was not painful. Head and orbits magnetic resonance imaging (MRI) showed mass lesions over the bilateral lacrimal glands, submandibular glands, and left foramen of ovale...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27631245/hiv-and-cancer-registry-linkage-identifies-a-substantial-burden-of-cancers-in-persons-with-hiv-in-india
#13
Sheela V Godbole, Karabi Nandy, Mansi Gauniyal, Pallavi Nalawade, Suvarna Sane, Shravani Koyande, Joy Toyama, Asha Hegde, Phil Virgo, Kishor Bhatia, Ramesh S Paranjape, Arun R Risbud, Sam M Mbulaiteye, Ronald T Mitsuyasu
We utilized computerized record-linkage methods to link HIV and cancer databases with limited unique identifiers in Pune, India, to determine feasibility of linkage and obtain preliminary estimates of cancer risk in persons living with HIV (PLHIV) as compared with the general population.Records of 32,575 PLHIV were linked to 31,754 Pune Cancer Registry records (1996-2008) using a probabilistic-matching algorithm. Cancer risk was estimated by calculating standardized incidence ratios (SIRs) in the early (4-27 months after HIV registration), late (28-60 months), and overall (4-60 months) incidence periods...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27630925/spectrum-of-radiological-manifestations-in-lymphoproliferative-malignancies-with-unusual-extra-nodal-soft-tissue-involvement
#14
Shantiranjan Sanyal, Kahila Prasad, Lalendra Upreti, Umesh Chandra Garga
Lymphoproliferative malignancies constitute a wide spectrum of haematological malignancies and their prevalence is widely increasing. Non-Hodgkin lymphomas and Hodgkin disease, frequently involve extranodal soft tissue structures in the head and neck, thorax and abdomen. These malignancies may involve virtually any type of soft tissues to any extent; hence many different imaging manifestations are possible which may mimic other disorders. The imaging characteristics of extranodal lymphomatous soft tissue involvement are described and classified here according to the site of involvement in 6 cases (primary diseases with orbital, muscle, extra testicular, scalp, sinonasal and pachymeningeal/dural involvement)...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27625965/a-case-report-of-primary-orbital-non-hodgkin-s-lymphoma-causing-complete-vision-loss
#15
Neerav Lamba, Douglas P Dworak, Shyam A Patel, Rohini Chennuri
A 29-year-old male with acquired immunodeficiency syndrome presented with a week of left eye blurriness, which then progressed to complete vision loss. On exam, the left pupil was nonreactive to light, and fundoscopy showed significant optic nerve edema. CT and MRI of the left orbit showed a mass lesion compressing the posterior aspect of the sclera with diffuse thickening and contrast enhancement of the retrobulbar portion of the left optic nerve. The lesion demonstrated low T1 and intermediate T2 intensities and heterogeneous contrast enhancement and measured 17...
2016: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/27614509/-radiotherapy-for-localized-gastric-and-orbital-malt-lymphomas
#16
L Quéro, C Hennequin, S Amorim, S Guillerm, A Ruskoné-Fourmestraux, C Thieblemont
Primary gastric and orbital MALT lymphomas are both low grade (indolent) B-cell non-Hodgkin's lymphomas. Traditionally, these tumors are radiosensitive and have a good prognosis. In localized orbital and stages IE-IIE gastric MALT lymphomas without Helicobacter pylori infection or in case of persistent H. pylori infection after eradication therapy, several retrospective studies have shown that radiotherapy was an effective and well-tolerated treatment.
October 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/27604535/secondary-bilateral-orbital-involvement-from-primary-non-hodgkin-lymphoma-of-the-cheek
#17
Shungo Furudoi, Takashi Yoshii, Takahide Komori
We describe a patient with oculomotor nerve palsy due to secondary orbital infiltration from the primary malignant lymphoma of the cheek. The patient was a 78-year-old female who had non-Hodgkin lymphoma (diffuse large B cell lymphoma [DLBCL]) of the cheek. The patient received chemotherapy and local radiation therapy. The combined treatment brought about complete remission. About 6 months after the last treatment the patient began to have left blepharoptosis and impaired vision. Findings from ophthalmological and neurosurgical examinations suggested no intraorbital or intracranial lesions...
2016: Kobe Journal of Medical Sciences
https://www.readbyqxmd.com/read/27468099/-lymphoma-of-ocular-and-periocular-tissues-clinicopathological-correlations
#18
I Schmack, H E Grossniklaus, S Hartmann
Lymphomas of the ocular adnexa and intraocular tissue include a wide range of lymphoproliferative neoplastic disorders. They are predominantly extranodal non-Hodgkin lymphomas (NHL). The World Health Organization (WHO) classification of lymphoid neoplasm and individual morphological, immunophenotypical, and molecular genetic features, indicate that they may be divided into B-cell (approximately 80 % of all NHL) and T-cell lymphomas (approximately 10-20 % of all NHL). The most common forms of ocular NHL are extranodal marginal zone lymphoma (EMZL) of the mucosa-associated lymphoid tissue (MALT-type), follicular lymphoma (FL), diffuse large B-cell lymphoma, and mantel cell lymphoma...
July 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27443585/sinonasal-inflammatory-myofibroblastic-tumor-with-anaplastic-lymphoma-kinase-1-rearrangement-case-study-and-literature-review
#19
Ghizlene Lahlou, Marion Classe, Michel Wassef, Pierre-Alexandre Just, Nicolas Le Clerc, Philippe Herman, Benjamin Verillaud
Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal tumors initially described in the lung. About half of them exhibit expression of the ALK1 protein, generally resulting from a gene rearrangement. Paranasal sinus IMTs are extremely uncommon, and gene rearrangement of ALK1 is very rare in this localization. A 47-year-old woman presented with rapidly progressive vision loss in her left eye. Clinical and imaging work-up revealed a tumor invading the left ethmoidal and sphenoidal sinuses and extending into the nasal cavity, the orbit and the skull base...
July 21, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27440138/case-report-of-subcutaneous-panniculitis-like-t-cell-lymphoma-complicated-by-eyelid-swelling
#20
Ryuya Hashimoto, Michihiro Uchiyama, Takatoshi Maeno
BACKGROUND: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare, highly malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose tissue. No case of SPTCL with the earliest symptoms occurring in the eye region has been reported. We report a case of SPTCL complicated by eyelid swelling. CASE PRESENTATION: A 19-year-old Japanese man presented with worsening left eyelid swelling. The patient's best-corrected visual acuity (BCVA) was 0...
2016: BMC Ophthalmology
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