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https://www.readbyqxmd.com/read/28209338/the-pharmacist-role-in-the-development-and-implementation-of-a-naloxone-prescription-program-in-alabama
#1
Jordan L Wulz, Hanna Sung, B DeeAnn Dugan, Terri M Wensel, Roger Lander, Bryn Manzella
OBJECTIVE: The purpose of this report is to describe the development and implementation of a pharmacist-led naloxone-training and prescription service at a county health department. SETTING: Jefferson County Department of Health, Birmingham, Alabama. PRACTICE DESCRIPTION: This service was developed in response to the overwhelming heroin and opioid epidemic that is currently affecting the entire nation and which is highly prevalent in the state of Alabama...
February 10, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28182158/demographic-characteristics-and-clinical-outcome-of-work-related-open-globe-injuries-in-the-most-industrialised-region-of-turkey
#2
Sertaç Argun Kıvanç, Berna Akova Budak, Emina Skrijelj, Mediha Tok Çevik
OBJECTIVES: To evaluate demographic characteristics and clinical outcomes of work-related open globe injuries in the most industrialized region of Turkey. MATERIALS AND METHODS: The demographic and medical records of patients with work-related open globe injuries who presented to the ophthalmology or emergency departments with an official occupational accident report were retrospectively reviewed. Visual acuity categories were defined according to the World Health Organization...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28176671/the-perceptions-and-attitudes-of-medical-students-towards-trauma-and-orthopaedic-teaching-a-cross-sectional-study
#3
Tarek Boutefnouchet, Basil Budair
OBJECTIVES: This study aimed to identify how undergraduate students perceive learning opportunities available to them and to determine whether students with an interest in trauma and orthopaedic (T&O) surgery have different perceptions and attitudes towards learning. METHODS: All fourth year medical students from the University of Birmingham Medical School (UK) were surveyed regarding their career intentions and their attitudes towards the teaching received in trauma and orthopaedic surgery...
2017: SICOT-J
https://www.readbyqxmd.com/read/28162098/the-effect-of-universal-decolonization-with-screening-in-critical-care-to-reduce-mrsa-across-an-entire-hospital
#4
Craig W Bradley, Martyn A C Wilkinson, Mark I Garvey
OBJECTIVE To describe the effect of universal methicillin-resistant Staphylococcus aureus (MRSA) decolonization therapy in a large intensive care unit (ICU) on the rates of MRSA cases and acquisitions in a UK hospital. DESIGN Descriptive study. SETTING University Hospitals Birmingham (UHB) NHS Foundation Trust is a tertiary referral teaching hospital in Birmingham, United Kingdom, that provides clinical services to nearly 1 million patients every year. METHODS A break-point time series analysis and kernel regression models were used to detect significant changes in the cumulative monthly numbers of MRSA bacteremia cases and acquisitions from April 2013 to August 2016 across the UHB system...
February 6, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28161135/temporomandibular-total-joint-prosthesis-infections-a-ten-year-retrospective-analysis
#5
W S McKenzie, P J Louis
A retrospective review of 178 total temporomandibular joint replacements (TJR) performed on 106 patients at the University of Alabama at Birmingham during the years 2000-2010 was completed. Data regarding sex, past medical history, prosthesis manufacturer, microbiology, antibiotic therapy, and the need for additional procedures were obtained from the medical records of patients who developed a prosthetic joint infection following TJR. Of the 106 patients, 95 (89.6%) were female and 11 (10.4%) were male. The average age of the patients was 47 years (range 19-68 years)...
February 1, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28152748/patient-activation-measures-distress-levels-and-causes-of-distress-in-chronic-lymphocytic-leukemia
#6
Emily Van Laar, Uma Borate, Bradford E Jackson, Maria Pisu, Pamela M Peters, Thomas Wayne Butler, Randall S Davis, Amitkumar Mehta, Aras Acemgil, Sara J Knight, Monika M Safford, Gabrielle Betty Rocque
: 201 Background: Patients with chronic lymphocytic leukemia (CLL) reporting high levels of distress due to knowledge gaps and emotional concerns can have negative outcomes and suffer from lower quality of life. Understanding patients' activation levels, causes of distress, knowledge gaps, and psychosocial needs are crucial in high quality care. Optimally activated, educated and empowered patients are better positioned to communicate effectively with providers regarding selection of, and adherence to, CLL treatment protocols and long-term care plans, and potentially improving quality of life...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152701/shared-decision-making-in-chronic-lymphocytic-leukemia-preferences-and-perceptions-of-patients-providers-and-navigators
#7
Emily Van Laar, Uma Borate, Karina I Halilova, Pamela M Peters, Bradford E Jackson, Maria Pisu, Thomas Wayne Butler, Randall S Davis, Amitkumar Mehta, Aras Acemgil, Sara J Knight, Monika M Safford
: 221 Background: In recent years, new treatments for chronic lymphocytic leukemia (CLL) with excellent response rates and varying toxicity profiles have emerged. In the setting of multiple available options, shared decision-making is critical. Developing strategies to enhance shared decision-making requires better understanding of how patients and providers make treatment decisions. METHODS: Patients with CLL and health care providers within the University of Alabama at Birmingham Health System Cancer Community Network were to assess how treatment decisions are made...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152168/life-space-mobility-change-predicts-6-month-mortality
#8
Richard E Kennedy, Patricia Sawyer, Courtney P Williams, Alexander X Lo, Christine S Ritchie, David L Roth, Richard M Allman, Cynthia J Brown
OBJECTIVES: To examine 6-month change in life-space mobility as a predictor of subsequent 6-month mortality in community-dwelling older adults. DESIGN: Prospective cohort study. SETTING: Community-dwelling older adults from five Alabama counties in the University of Alabama at Birmingham (UAB) Study of Aging. PARTICIPANTS: A random sample of 1,000 Medicare beneficiaries, stratified according to sex, race, and rural or urban residence, recruited between November 1999 and February 2001, followed by a telephone interview every 6 months for the subsequent 8...
February 2, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28138233/birmingham-copd-cohort-a-cross-sectional-analysis-of-the-factors-associated-with-the-likelihood-of-being-in-paid-employment-among-people-with-copd
#9
Kiran K Rai, Rachel E Jordan, W Stanley Siebert, Steven S Sadhra, David A Fitzmaurice, Alice J Sitch, Jon G Ayres, Peymané Adab
BACKGROUND: Employment rates among those with chronic obstructive pulmonary disease (COPD) are lower than those without COPD, but little is known about the factors that affect COPD patients' ability to work. METHODS: Multivariable analysis of the Birmingham COPD Cohort Study baseline data was used to assess the associations between lifestyle, clinical, and occupational characteristics and likelihood of being in paid employment among working-age COPD patients. RESULTS: In total, 608 of 1,889 COPD participants were of working age, of whom 248 (40...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28135390/improving-quality-outcomes-in-veteran-centric-care
#10
Tristan T Tave, Daniel R Wyers, Catherine Schreiber-Jones, Susanne A Fogger, Teena M McGuinness
The University of Alabama at Birmingham (UAB) School of Nursing and the Birmingham Veterans Affairs Medical Center (BVAMC) created a Psychiatric-Mental Health Nurse Practitioner (PMHNP) Residency Continuity Clinic tasked with providing Veteran-centric mental health outpatient treatment informed by measurement-based care (MBC) to provide quality outcomes. Approved by the BVAMC, the UAB Institutional Review Board also approved and exempted the project as quality improvement. PMHNP residents administered the Patient Stress Questionnaire (PSQ)-an MBC tool that incorporates validated tools for assessing depression, anxiety, posttraumatic stress, alcohol use, and pain-to each Veteran from March to August 2016...
January 1, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28134074/chest-and-renal-involvements-birmingham-vascular-activity-score-more-than-13-5-and-five-factor-score-1996-more-than-1-at-diagnosis-are-significant-predictors-of-relapse-of-microscopic-polyangiitis
#11
Yoon-Jeong Oh, Sung Soo Ahn, Eun Seong Park, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
OBJECTIVES: We investigated whether specified organ involvements, antineutrophil cytoplasmic antibody (ANCA) positivity, Birmingham vasculitis activity score (BVAS) and five factor scores (FFS) at diagnosis could predict relapse of microscopic polyangiitis (MPA). METHODS: We reviewed the medical records of 90 patients with MPA. We collected clinical and prognostic data, (MPO)-ANCA and proteinase 3 (PR3)-ANCA, BVAS and FFS at diagnosis, and we compared them between the two groups...
January 19, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28132120/mentoring-university-students-with-asd-a-mentee-centered-approach
#12
Nicole Roberts, Elina Birmingham
This study presents a conceptual understanding of how mentorship is experienced by the participants of a mentorship program for university students with Autism Spectrum Disorder. We interviewed the participants of the Autism Mentorship Initiative at Simon Fraser University. A grounded theory approach was used to systematically organize data from interviews and documents to reveal themes that were salient to the mentees (students with autism; n = 9) and mentors (neurotypical students; n = 9). The following five main themes were identified and interrelated under the core theme of A Mentee-centered Approach: (1) The Natural Progression of the Relationship, (2) The Supportive Mentor, (3) The Meeting Process, (4) Identifying and Implementing Goals, and (5) Learning Together...
January 28, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28130472/long-term-functional-outcome-in-patients-with-acquired-infections-after-acute-spinal-cord-injury
#13
Marcel A Kopp, Ralf Watzlawick, Peter Martus, Vieri Failli, Felix W Finkenstaedt, Yuying Chen, Michael J DeVivo, Ulrich Dirnagl, Jan M Schwab
OBJECTIVE: To investigate whether prevalent hospital-acquired pneumonia and wound infection affect the clinical long-term outcome after acute traumatic spinal cord injury (SCI). METHODS: This was a longitudinal cohort study within the prospective multicenter National Spinal Cord Injury Database (Birmingham, Alabama). We screened datasets of 3,834 patients enrolled in 20 trial centers from 1995 to 2005 followed up until 2016. Eligibility criteria were cervical SCI and American Spinal Cord Injury Association impairment scale A, B, and C...
January 27, 2017: Neurology
https://www.readbyqxmd.com/read/28127938/an-open-label-randomized-bioavailability-study-of-alternative-methods-of-oral-administration-of-naloxegol-in-healthy-subjects
#14
Khanh Bui, Bruce Birmingham, Ulysses Diva, Bruce Berger
Naloxegol is a peripherally acting μ-opioid receptor antagonist approved as an orally administered tablet for the treatment of opioid-induced constipation. Patients with swallowing difficulties may benefit from alternative approaches to the oral administration of the whole-tablet formulation of naloxegol. This open-label, randomized, 4-period, 4-treatment, crossover, single-dose study (NCT02446171) evaluated the pharmacokinetic (PK) characteristics of crushed naloxegol 25-mg tablets (suspended in water) administered orally or by nasogastric tube and a naloxegol solution compared with the commercially available 25-mg tablet formulation in healthy volunteers...
January 27, 2017: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/28127867/application-of-biocatalysis-to-on-dna-carbohydrate-library-synthesis
#15
Baptiste Thomas, Xiaojie Lu, William Birmingham, Kun Huang, Peter Both, Juana Reyes Martinez, Robert Young, Christopher Davie, Sabine Flitsch
DNA-encoded libraries are increasingly used for the discovery of bioactive lead compounds in high-throughput screening programmes against specific biological targets. Although a number of libraries are now available, they cover limited chemical space due to bias in ease of synthesis and the lack of chemical reactions that are compatible with DNA-tagging. For example, compound libraries rarely contain complex biomolecules such as carbohydrates with high level of functionality, stereochemistry and hydrophilicity...
January 26, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28125760/resource-use-and-medicare-costs-during-lay-navigation-for-geriatric-patients-with-cancer
#16
Gabrielle B Rocque, Maria Pisu, Bradford E Jackson, Elizabeth A Kvale, Wendy Demark-Wahnefried, Michelle Y Martin, Karen Meneses, Yufeng Li, Richard A Taylor, Aras Acemgil, Courtney P Williams, Nedra Lisovicz, Mona Fouad, Kelly M Kenzik, Edward E Partridge
Importance: Lay navigators in the Patient Care Connect Program support patients with cancer from diagnosis through survivorship to end of life. They empower patients to engage in their health care and navigate them through the increasingly complex health care system. Navigation programs can improve access to care, enhance coordination of care, and overcome barriers to timely, high-quality health care. However, few data exist regarding the financial implications of implementing a lay navigation program...
January 26, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28124439/rates-of-criminal-victimization-in-an-early-intervention-for-psychosis-service-a-cross-sectional-survey
#17
Rowena Jones, Luke Banbury
BACKGROUND: There is a growing body of research looking into the high rates of victimization amongst people with severe mental illness. Studies to date have tended to look at victimization rates in people with chronic mental illness over a wide age range. However, national crime surveys indicate that younger people are more likely to be the victim of crime than older people. There is also evidence that people from ethnic minorities are more likely to experience and less likely to report criminal victimization...
January 26, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28124392/precision-medicine-at-the-university-of-alabama-at-birmingham-laying-the-foundational-processes-through-implementation-of-genotype-guided-antiplatelet-therapy
#18
REVIEW
Shuko Harada, Yaolin Zhou, Steve Duncan, Alicia R Armstead, Gina M Coshatt, Chrisly Dillon, Brigitta C Brott, James Willig, Jorge A Alsip, William B Hillegass, Nita A Limdi
Despite evidence that genotype-guided therapy (GGTx) can improve outcomes, advances in genotyping technology and decreasing costs, integration into practice is limited. We describe a successful implementation framework using genotype-guided antiplatelet therapy as an example. We outline how we developed consensus across stakeholders, obtained institutional endorsement, built genotyping capability, and provide decision support to guide treatment selection; and demonstrate how to leverage such efforts to assess clinical effectiveness and cost-effectiveness and bolster research infrastructure...
January 25, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28118526/gout-self-management-in-african-american-veterans-a-qualitative-exploration-of-challenges-and-solutions-from-patients-perspectives
#19
Jasvinder A Singh, Ivan Herbey, Aseem Bharat, Janet E Dinnella, Sally Pullman-Mooar, Seth Eisen, Nataliya Ivankova
OBJECTIVE: To explore gout self-management and associated challenges and solutions in African-Americans. METHODS: We conducted semi-structured interviews with 35 African-Americans veterans with gout, who received healthcare at Birmingham or Philadelphia Veterans Affairs (VA) medical centers, had filled urate-lowering therapy (ULT; most commonly allopurinol) for at least 6 months and had ULT a medication possession ratio ≥80%. The interview protocol was constructed to explore key concepts related to gout self-management, including: initial diagnosis of gout, beginning medical care for gout, the course of the gout, ULT medication adherence, dietary strategies, comorbidity and side effects, and social support...
January 24, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28108170/birmingham-hip-resurfacing-in-patients-55-years-or-younger-risk-factors-for-poor-midterm-outcomes
#20
Mohamad J Halawi, David Brigati, William Messner, Peter J Brooks
BACKGROUND: Birmingham hip resurfacing (BHR) is the only Food and Drug Administration-approved hip resurfacing system available in the United States and is used as an alternative to conventional total hip arthroplasty in younger patients. The purpose of this study is to report on the midterm outcomes of BHR in patients 55 years and younger, and specifically to examine the risk factors for aseptic failure, all-cause revision, and complications in this patient population. METHODS: Four hundred forty-two consecutive patients with 5-year follow-up were retrospectively reviewed...
January 3, 2017: Journal of Arthroplasty
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