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https://www.readbyqxmd.com/read/29769371/how-are-we-currently-training-and-maintaining-clinical-readiness-of-us-and-uk-military-surgeons-responsible-for-managing-head-face-and-neck-wounds-on-deployment
#1
John Breeze, J G Combes, J DuBose, D B Powers
INTRODUCTION: The conflicts in Iraq and Afghanistan provided military surgeons from the USA and the UK with extensive experience into the management of injuries to the head, face and neck (HFN) from high energy bullets and explosive weaponry. The challenge is now to maintain the expertise in managing such injuries for future military deployments. METHODS: The manner in which each country approaches four parameters required for a surgeon to competently treat HFN wounds in deployed military environments was compared...
May 16, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29769368/the-reconstructive-trauma-surgery-interface-fellowship-and-its-applicability-to-military-and-civilian-trainees
#2
EDITORIAL
Douglas Hammond, J Breeze, D Evriviades
The Reconstructive Trauma Surgery Fellowship is a based at the Queen Elizabeth Hospital, Birmingham, and focuses on the multidisciplinary management of major trauma from presentation to discharge. It is unique to the UK in that it provides both management and leadership experience as well as operative surgical skills particularly in terms of reconstruction on complex trauma patients including those from the military. This paper describes the relevance of fellowships in modern surgical training, composition of the reconstructive trauma fellowship and the relevance for both civilian and military trainees...
May 16, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29769093/granulomatosis-with-polyangiitis-a-17-year-experience-from-a-tertiary-care-hospital-in-pakistan
#3
Omar Irfan, Haris Khan, Zarrar Khan, Alina Ashraf, Rimsha Ahmed, Javaid Ahmad Khan, Ali Bin Sarwar Zubairi
OBJECTIVE: Granulomatosis with Polyangiitis (GPA) is an autoimmune, multi-system, small and medium vessel vasculitis with granulomatous inflammation. Aim of this study was to assess the clinical and radiological presentations of patients with GPA amongst the Pakistani population. It is a single centre retrospective single observation study. RESULTS: Study was conducted at the Aga Khan University Hospital, Karachi with records were reviewed from January 2000 to December 2017...
May 16, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29759952/head-and-neck-anatomy-effect-of-focussed-near-peer-teaching-on-anatomical-confidence-in-undergraduate-medical-students
#4
Simon Morris, Max Sallis Osborne, Duncan Bowyer
OBJECTIVES: To assess the effect of near-peer head and neck anatomy teaching on undergraduates and to quantify the benefit from a focussed teaching course. Near-peer teaching involves colleagues within close seniority and age proximity teaching one another on a specified topic. DESIGN: Small group teaching sessions were delivered to medical students on 3 key areas of ENT anatomy. Participants were given a precourse and postcourse questionnaire to determine the benefit attained from the course...
May 11, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29757901/revascularization-time-in-liver-transplantation-independent-prediction-of-inferior-short-and-long-term-outcomes-by-prolonged-graft-implantation
#5
Bettina M Buchholz, Undine A Gerlach, Vishnu V Chandrabalan, James Hodson, Bridget K Gunson, Hynek Mergental, Paolo Muiesan, John R Isaac, Keith J Roberts, Darius F Mirza, M Thamara Pr Perera
BACKGROUND: Strategies for successful transplantation are much needed in the era of organ shortage and there has been a resurgence of interest on the impact of revascularization time (RT) on outcomes in liver transplantation (LT). METHODS: All primary LT performed in Birmingham between 2009 and 2014 (n=678) with portal reperfusion first were stratified according to RT (<44 vs. ≥44 min) and graft quality (SLG, Donor risk index [DRI] <2.3 vs. MLG, DRI ≥2...
May 2, 2018: Transplantation
https://www.readbyqxmd.com/read/29754328/hbsag-negative-and-anti-hbc-positive-in-eosinophilic-granulomatosis-with-polyangiitis-a-retrospective-pilot-study
#6
Sang-Won Lee, Do Young Kim, Sang Hoon Ahn, Yong-Beom Park, Kwang-Hyub Han, Jun Yong Park
We examined whether resolved hepatitis B virus (HBV) infection was associated with antineutrophil cytoplasmic antibody-associated vasculitis (AAV), and affected AAV activity at diagnosis and prognosis during the follow-up. We reviewed the electronic medical records of 153 AAV patients, and included 91 hepatitis B surface antigen (HBsAg)-negative patients having results of both antibody to hepatitis B core antigen (anti-HBc) and surface antigen (anti-HBs). We collected clinical and laboratory data, Birmingham vasculitis activity score (BVAS) and five factor scores (FFS) at diagnosis and relapse rates during the follow-up...
May 12, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29753137/perceptions-of-intersectional-stigma-among-diverse-women-living-with-hiv-in-the-united-states
#7
Whitney S Rice, Carmen H Logie, Tessa M Napoles, Melonie Walcott, Abigail W Batchelder, Mirjam-Colette Kempf, Gina M Wingood, Deborah J Konkle-Parker, Bulent Turan, Tracey E Wilson, Mallory O Johnson, Sheri D Weiser, Janet M Turan
Attitudes and behavior that devalue individuals based upon their HIV status (HIV-related stigma) are barriers to HIV prevention, treatment, and wellbeing among women living with HIV. Other coexisting forms of stigma (e.g., racism, sexism) may worsen the effects of HIV-related stigma, and may contribute to persistent racial and gendered disparities in HIV prevention and treatment. Few studies examine perceptions of intersectional stigma among women living with HIV. From June to December 2015, we conducted 76 qualitative interviews with diverse women living with HIV from varied socioeconomic backgrounds enrolled in the Women's Interagency HIV Study (WIHS) in Birmingham, Alabama; Jackson, Mississippi; Atlanta, Georgia; and San Francisco, California...
May 4, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29752996/unmasking-leading-to-a-health-care-worker-mycobacterium-tuberculosis-transmission
#8
Kerry L Holden, Craig W Bradley, Evonne T Curran, Christopher Pollard, Grace Smith, Elisabeth Holden, Patricia Glynn, Mark Garvey
BACKGROUND: Mycobacterium tuberculosis is a major health burden worldwide. The disease can present as an individual case, community outbreak or more rarely a nosocomial outbreak. Even in countries with a low prevalence such as the UK, tuberculosis (TB) presents a risk to healthcare workers (HCWs). AIM: To report an outbreak which manifested 12 months after a patient with pulmonary tuberculosis was admitted to Queen Elizabeth Hospital Birmingham (QEHB). METHODS: We present the epidemiological and outbreak investigations; the role of whole genome sequencing (WGS) in identifying the outbreak and control measures to prevent further outbreaks...
May 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29741397/preliminary-normative-data-on-the-borb-for-children-aged-3-8
#9
Ruth Brunsdon, Pamela Joy, Erin Patten, Karen Burton
The Birmingham Object Recognition Battery (BORB) is a theoretically based test battery that is used in adult cognitive neuropsychology in research and for clinical assessment. It allows a detailed analysis of underlying impairments in individuals with brain injury who have visual object recognition difficulties. The BORB's usefulness in pediatrics is supported by numerous research studies. However, there is no published normative data for children, making clinical use of the test difficult. The aim of this brief report is to publish some preliminary normative data in 70 children aged between 3 and 8 years to assist both researchers and clinicians with interpretation of test scores...
May 9, 2018: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/29734289/the-impact-of-patient-navigation-on-diabetes
#10
Thomas M English, David Masom, Marilyn V Whitman
Diabetes is a growing concern in the United States as it is associated with increasing rates of mortality and morbidity, in addition to rising healthcare costs. It is the seventh-leading cause of death in the U.S. From 1980 through 2014, the number of Americans diagnosed with diabetes increased fourfold (from 5.5 million to 22 million). Consequently, costs associated with diabetes have soared to an estimated $245 billion, representing an average annual cost of approximately $13,700 per patient with diabetes...
May 2018: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/29732396/incidence-and-outcomes-of-neonatal-acute-kidney-injury-awaken-a-multicentre-multinational-observational-cohort-study
#11
Jennifer G Jetton, Louis J Boohaker, Sidharth K Sethi, Sanjay Wazir, Smriti Rohatgi, Danielle E Soranno, Aftab S Chishti, Robert Woroniecki, Cherry Mammen, Jonathan R Swanson, Shanty Sridhar, Craig S Wong, Juan C Kupferman, Russell L Griffin, David J Askenazi
Background: Single-center studies suggest that neonatal acute kidney injury (AKI) is associated with poor outcomes. However, inferences regarding the association between AKI, mortality, and hospital length of stay are limited due to the small sample size of those studies. In order to determine whether neonatal AKI is independently associated with increased mortality and longer hospital stay, we analyzed the Assessment of Worldwide Acute Kidney Epidemiology in Neonates (AWAKEN) database...
November 2017: The lancet child & adolescent health
https://www.readbyqxmd.com/read/29730641/peptalk2-results-of-a-pilot-randomised-controlled-trial-to-compare-vzig-and-aciclovir-as-postexposure-prophylaxis-pep-against-chickenpox-in-children-with-cancer
#12
Jessica Bate, Stephen Baker, Judith Breuer, Julia C Chisholm, Juliet Gray, Sophie Hambleton, Aimee Houlton, Mark Jit, Stephen Lowis, Guy Makin, Catherine O'Sullivan, Soonie R Patel, Robert Phillips, Neil Ransinghe, Mary Elizabeth Ramsay, Roderick Skinner, Keith Wheatley, Paul T Heath
OBJECTIVE: To determine the likely rate of patient randomisation and to facilitate sample size calculation for a full-scale phase III trial of varicella zoster immunoglobulin (VZIG) and aciclovir as postexposure prophylaxis against chickenpox in children with cancer. DESIGN: Multicentre pilot randomised controlled trial of VZIG and oral aciclovir. SETTING: England, UK. PATIENTS: Children under 16 years of age with a diagnosis of cancer: currently or within 6 months of receiving cancer treatment and with negative varicella zoster virus (VZV) serostatus at diagnosis or within the last 3 months...
May 5, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29725643/combination-therapy-with-rituximab-and-cyclophosphamide-for-remission-induction-in-anca-vasculitis
#13
Frank B Cortazar, Saif A Muhsin, William F Pendergraft, Zachary S Wallace, Colleen Dunbar, Karen Laliberte, John L Niles
Introduction: Remission induction in antineutrophil cytoplasmic autoantibody (ANCA) vasculitis may be complicated by slow response to treatment and toxicity from glucocorticoids. We describe outcomes with a novel remission induction regimen combining rituximab with a short course of low-dose, oral cyclophosphamide and an accelerated prednisone taper. Methods: Patients were included in this retrospective study if they had newly diagnosed or relapsing ANCA vasculitis with a Birmingham Vasculitis Activity Score for Wegener Granulomatosis (BVAS-WG) ≥3 and received a standardized remission induction regimen...
March 2018: KI Reports
https://www.readbyqxmd.com/read/29721167/glycine-a-non-invasive-imaging-biomarker-to-aid-magnetic-resonance-spectroscopy-in-the-prediction-of-survival-in-paediatric-brain-tumours
#14
Ben Babourina-Brooks, Sarah Kohe, Simrandip K Gill, Lesley MacPherson, Martin Wilson, Nigel P Davies, Andrew C Peet
Paediatric brain tumours have a high mortality rate and are the most common solid tumour of childhood. Identification of high risk patients may allow for better treatment stratification. Magnetic Resonance Spectroscopy (MRS) provides a non-invasive measure of brain tumour metabolism and quantifies metabolite survival markers to aid in the clinical management of patients. Glycine can be identified using MRS and has been recently found to be important for cancer cell proliferation in tumours making it a valuable prognostic marker...
April 10, 2018: Oncotarget
https://www.readbyqxmd.com/read/29719058/trajectories-of-community-mobility-recovery-after-hospitalization-in-older-adults
#15
Christine Loyd, T Mark Beasley, Rebecca S Miltner, Diane Clark, Barbara King, Cynthia J Brown
OBJECTIVES: To identify trajectories of recovery of community mobility in acutely ill older adults using the University of Alabama at Birmingham Life-Space Assessment (LSA). DESIGN: Prospective observation cohort study. SETTING: Central Alabama, Birmingham Veterans Affairs Medical Center. PARTICIPANTS: Community-dwelling adults aged 65 and older hospitalized for nonsurgical medical reasons (N=173). MEASUREMENTS: We determined LSA scores for the month before and monthly for 6 months after hospitalization (composite scores ranging from 0-120, with 120 reflecting completely unrestricted mobility)...
May 2, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29709382/numbness-of-the-lower-lip-does-not-adversely-affect-quality-of-life-or-patients-satisfaction-after-mandibular-orthognathic-surgery
#16
Z Ahmad, J Breeze, R Williams
Measures of patient-reported quality of life (QoL) are increasingly being used to tailor services that are funded by Clinical Commissioning Groups (CCG) in England. Mandibular osteotomies may result in altered sensation of the lower lip, but we know of limited evidence about the resulting effect on QoL. The modified Bristol orthognathic patient outcomes questionnaire was given to patients who had mandibular osteotomies at the Queen Elizabeth Hospital, Birmingham, between March 2006 and April 2016. Questionnaires were collected at the final orthognathic postoperative appointment...
April 27, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29707076/clinical-predictors-for-repeat-hospitalizations-in-left-ventricular-assist-device-lvad-patients-with-gastrointestinal-bleeding
#17
Charles V Welden, Wiley Truss, Gerald McGwin, Frederick Weber, Shajan Peter
Background: Patients implanted with left ventricular assist devices (LVAD) carry an increased risk of gastrointestinal bleeding (GIB), estimated at 25% in most studies. Significant efforts are employed in localizing and stopping the source of bleeding, but the rates of repeat hospitalization for GIB remain surprisingly high. Given the increasing incidence of LVAD-dependent end-stage heart failure and the excessive costs associated with repetitive endoscopic investigations, risk factors associated with re-bleeding need to be determined...
April 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29705529/long-term-outcomes-of-patients-with-hcv-associated-cryoglobulinemic-vasculitis-after-virologic-cure
#18
Martín Bonacci, Sabela Lens, Zoe Mariño, María-Carlota Londoño, Sergio Rodriguez-Tajes, José M Sánchez-Tapias, Manel Ramos-Casals, José Hernández-Rodríguez, Xavier Forns
Patients with hepatitis C virus-associated cryoglobulinemic vasculitis (HCV-CV) have high rates of clinical remission after treatment with direct-acting antivirals (DAAs),but circulating cryoglobulins persist and vascular disorders reappear in some patients shortly after DAA treatment ends. We performed a prospective study to assess the long-term clinical and immune system effects of HCV eradication with DAAs in 46 patients with HCV-CV and 42 asymptomatic patients with circulating cryoglobulins. A median of 24 months after DAA treatment (range, 17-41 months), 66% of patients with HCV-CV and 70% of asymptomatic patients with circulating cryoglobulins had immunologic response, with comparable reductions in cryocrit from 2...
April 26, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29702538/utilization-of-declined-liver-grafts-yields-comparable-transplant-outcomes-and-previous-decline-should-not-be-a-deterrent-to-graft-use
#19
Francesca Marcon, Andrea Schlegel, David C Bartlett, Marit Kalisvaart, Dawn Bishop, Hynek Mergental, Keith J Roberts, Darius F Mirza, John Isaac, Paolo Muiesan, M Thamara Perera
BACKGROUND: In the United Kingdom, up to 20% of liver graft offers are not used for transplantation, and the reasons for graft refusal are multifactorial and not consistent among transplant units. METHODS: Liver grafts previously declined by other transplant centers in the United Kingdom but transplanted in our unit in Birmingham between 2011 and 2015 were analyzed. According to the indicated reason for previous declines, liver grafts were categorized into 3 refusal groups: "quality," "logistics," and "other reasons...
May 2018: Transplantation
https://www.readbyqxmd.com/read/29702517/assessing-repeated-sprint-ability-in-division-i-collegiate-women-soccer-players
#20
Robert G Lockie, Tricia M Liu, Alyssa A Stage, Adrina Lazar, Dominic V Giuliano, Jillian M Hurley, Ibett A Torne, Megan D Beiley, Samantha A Birmingham-Babauta, John J Stokes, Fabrice G Risso, DeShaun L Davis, Matthew R Moreno, Ashley J Orjalo
Lockie, RG, Liu, TM, Stage, AA, Lazar, A, Giuliano, DV, Hurley, JM, Torne, IA, Beiley, MD, Birmingham-Babauta, SA, Stokes, JJ, Risso, FG, Davis, DL, Moreno, MR, and Orjalo, AJ. Assessing repeated-sprint ability in Division I collegiate women soccer players. J Strength Cond Res XX(X): 000-000, 2018-Repeated-sprint ability (RSA) is a key component of soccer, and is the capacity to repeatedly produce near-maximal to maximal sprints with short recovery periods. Repeated-sprint ability has received little analysis in collegiate women soccer players...
April 26, 2018: Journal of Strength and Conditioning Research
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