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https://www.readbyqxmd.com/read/29682865/efficacy-of-forced-air-warming-for-preventing-perioperative-hypothermia-and-related-complications-in-patients-undergoing-laparoscopic-surgery-a-randomized-controlled-trial
#1
Shu-Fen Su, Hsiao-Chi Nieh
BACKGROUND: Perioperatively, unexpected hypothermia may cause adverse surgical outcomes. However, few studies have explored the efficacy of forced-air warming in patients undergoing laparoscopic surgery. AIM/OBJECTIVE: To determine the efficacy of forced-air warming for preventing perioperative hypothermia and complications in patients undergoing laparoscopic surgery. METHODS: A total of 127 participants undergoing laparoscopic thoracic or abdominal surgery were recruited between January and November 2015...
April 23, 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29682575/the-role-of-tympanic-membrane-retractions-in-cholesteatoma-pathogenesis
#2
Letícia Petersen Schmidt Rosito, Neil Sperling, Adriane Ribeiro Teixeira, Fábio André Selaimen, Sady Selaimen da Costa
Objective: To analyze the contralateral ear (CLE) of patients with cholesteatoma and to correlate the cholesteatoma growth pattern in the affected ear with the findings in the CLE. Methods: Videotoscopy of both ears in 432 patients with cholesteatomas classified as posterior epitympanic (PEC), posterior mesotympanic (PMC), two routes, or undetermined. Tympanic membrane (TM) retractions were classified by location and severity and TM perforations according to signs of previous TM retraction...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29678964/technology-enabled-examinations-of-cardiac-rhythm-optic-nerve-oral-health-tympanic-membrane-gait-and-coordination-evaluated-jointly-with-routine-health-screenings-an-observational-study-at-the-2015-kumbh-mela-in-india
#3
Pratik Shah, Gregory Yauney, Otkrist Gupta, Vincent Patalano Ii, Mrinal Mohit, Rikin Merchant, S V Subramanian
OBJECTIVES: Technology-enabled non-invasive diagnostic screening (TES) using smartphones and other point-of-care medical devices was evaluated in conjunction with conventional routine health screenings for the primary care screening of patients. DESIGN: Dental conditions, cardiac ECG arrhythmias, tympanic membrane disorders, blood oxygenation levels, optic nerve disorders and neurological fitness were evaluated using FDA-approved advanced smartphone powered technologies...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29674377/sensitive-high-frequency-hearing-in-earless-and-partially-eared-harlequin-frogs-atelopus
#4
Molly C Womack, Jakob Christensen-Dalsgaard, Luis A Coloma, Kim L Hoke
Harlequin frogs, genus Atelopus , communicate at high frequencies despite most species lacking a complete tympanic middle ear that facilitates high frequency hearing in most anurans and other tetrapods. Here we test whether Atelopus are better at sensing high frequency acoustic sound compared to other eared and earless species in the Bufonidae family, determine whether middle ear variation within Atelopus affects hearing sensitivity, and test potential hearing mechanisms in Atelopus We determine that at high frequencies (2000-4000 Hz) Atelopus are 10-34 dB more sensitive than other earless bufonids but are relatively insensitive to mid-range frequencies (900-1500 Hz) compared to eared bufonids...
April 19, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29668049/surgical-management-of-spontaneous-cerebrospinal-fistulas-and-encephaloceles-of-the-temporal-bone
#5
Joe Walter Kutz, Andrew K Johnson, Cameron C Wick
OBJECTIVES/HYPOTHESIS: To describe the presentation, surgical findings, and outcomes in patients with spontaneous temporal bone cerebrospinal fluid (CSF) fistulas and encephaloceles. STUDY DESIGN: Retrospective chart review. METHODS: A retrospective chart review of patients treated for a spontaneous temporal bone CSF fistula and/or encephalocele over a 10-year period was performed. Data recorded included demographic information, presenting signs and symptoms, radiographic and laboratory studies, surgical approach, materials used for repair, surgical complications, and successful closure of the CSF fistula...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29644162/clinical-study-on-middle-ear-diseases-in-children-with-orofacial-clefts
#6
Raja Kalaiarasi, Kamran A Syed, Chellappa Vijayakumar, Ajoy M Varghese, Mary John
Introduction Orofacial clefts are associated with middle ear diseases, but the magnitude of this problem is not generally well appreciated. The aim of this study was to describe the middle ear findings and audiological profile in children with orofacial clefts. Materials and methods Children with orofacial clefts attending plastic surgery and otorhinolaryngology departments of a tertiary hospital over one-year duration were included in this study. Ninety-six children with orofacial clefts were identified. They were categorized age-wise as zero to five years, more than five years to 10 years, and more than 10 years to 15 years...
February 8, 2018: Curēus
https://www.readbyqxmd.com/read/29628367/butterfly-cartilage-tympanoplasty-outcomes-a-single-institution-experience-and-literature-review
#7
Mejd Jumaily, Joel Franco, James A Gallogly, Joshua L Hentzelman, Dary J Costa, Alan P K Wild, Anthony A Mikulec
PURPOSE: In 1998, Dr. Eavey described the trans-canal inlay butterfly cartilage tympanoplasty technique, also known as cartilage button tympanoplasty. Many retrospective studies have since demonstrated its efficacy and decreased operative time when compared to underlay and overlay tympanoplasty techniques. The butterfly cartilage tympanoplasty approach uses only a cartilage graft to repair tympanic membrane perforations. The aim of this study was to review the literature for studies that examined butterfly cartilage tympanoplasty success rates and outcomes and compare them to outcomes from our cohort...
March 29, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29623476/transcription-and-microrna-profiling-of-cultured-human-tympanic-membrane-epidermal-keratinocytes
#8
Peder Aabel, Tor Paaske Utheim, Ole Kristoffer Olstad, Helge Rask-Andersen, Rodney James Dilley, Magnus von Unge
The human tympanic membrane (TM) has a thin outer epidermal layer which plays an important role in TM homeostasis and ear health. The specialised cells of the TM epidermis have a different physiology compared to normal skin epidermal keratinocytes, displaying a dynamic and constitutive migration that maintains a clear TM surface and assists in regeneration. Here, we characterise and compare molecular phenotypes in keratinocyte cultures from TM and normal skin. TM keratinocytes were isolated by enzymatic digestion and cultured in vitro...
April 5, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29619111/intratympanic-gentamicin-for-intractable-m%C3%A3-ni%C3%A3-re-s-disease-a-review-and-analysis-of-audiovestibular-impact
#9
Sertaç Yetişer
Introduction  Intratympanic gentamicin regulates the symptoms in most patients with incapacitating Ménière's disease. The treatment protocols have changed over the years from medical labyrinthectomy to preservation of vestibular function. Objectives  This study aims to review the audiovestibular response related to the effect of the drug in controlling vertigo. Data Synthesis  Articles were identified by means of a search in the PubMed database using the key words Meniere and intratympanic or transtympanic gentamicin ...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29611410/total-transcanal-endoscopic-facial-nerve-decompression-for-traumatic-facial-nerve-palsy
#10
Aveline Aloyce Kahinga, Ji Hyuk Han, In Seok Moon
A few approaches can be used to decompress traumatic facial nerve paralysis including the middle cranial fossa approach or transmastoid approach depending on the site of injury. In some specific situation of treating traumatic facial nerve palsy whose injured site was confined from the geniculate ganglion to the second genu, transcanal endoscopic approach for facial nerve decompression can be used. We performed two cases of total endoscopic transcanal facial nerve decompression in patients with traumatic facial nerve palsy...
May 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29608150/trans-tympanic-drug-delivery-for-the-treatment-of-ototoxicity
#11
Kelly Sheehan, Sandeep Sheth, Debashree Mukherjea, Leonard P Rybak, Vickram Ramkumar
The systemic administration of protective agents to treat drug-induced ototoxicity is limited by the possibility that these protective agents could interfere with the chemotherapeutic efficacy of the primary drugs. This is especially true for the drug cisplatin, whose anticancer actions are attenuated by antioxidants which provide adequate protection against hearing loss. Other current or potential otoprotective agents could pose a similar problem, if administered systemically. The application of various biologicals or protective agents directly to the cochlea would allow for high levels of these agents locally with limited systemic side effects...
March 16, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29594077/results-of-type-i-tympanoplasty-using-fascia-with-or-without-cartilage-reinforcement-10-years-experience
#12
Ali Kouhi, Mohammad Taghi Khorsandi Ashthiani, Mir Mohammad Jalali
Introduction: There remains controversy about the optimal kind of graft to repair tympanic membrane. The purpose of this study was to evaluate the anatomical and auditory outcomes of type I tympanoplasty using fascia with or without cartilage reinforcement. Materials and Methods: This retrospective cohort study was conducted from 2005 to 2015. All cases were surgically treated by a single surgeon. We excluded cases in which the etiology of chronic otitis media was cholesteatoma...
March 2018: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29588156/-tumulus-stabilization-of-a-total-ossicular-replacement-prosthesis
#13
T Mom, C Caburet, N Saroul, L Gilain, M Gersdorff
Functional failure of total ossicular replacement prostheses (TORP) is often due to secondary displacement, ranging from simple subluxation to prosthesis extrusion following recurrence of severe tympanic membrane retraction. Several surgical techniques have been proposed to stabilize a TORP, mostly using superimposed non-organic or resorbable heterologous materials. We describe a simple so-called "tumulus" surgical technique that limits prosthesis displacement and extrusion, regardless of the type of TORP, by using a few fragments of autologous cartilage that are always available and perfectly tolerated at no cost...
March 24, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29587475/microbiological-results-from-middle-ear-effusion-in-pediatric-patients-receiving-ventilation-tube-insertion-multicenter-registry-study-on-the-effectiveness-of-ventilation-tube-insertion-in-pediatric-patients-with-chronic-otitis-media-with-effusion-part-i
#14
Myung Hoon Yoo, Yang-Sun Cho, June Choi, Yun Hoon Choung, Jae-Ho Chung, Jong Woo Chung, Gyu Cheol Han, Eun-Ju Jeon, Beom Cho Jun, Dong-Kee Kim, Kyu Sung Kim, Jun Ho Lee, Kyu-Yup Lee, Seung Hwan Lee, In Seok Moon, Hong Ju Park, Shi Nae Park, Jihye Rhee, Jae Hyun Seo, Seung Geun Yeo
Objectives: The aim of this multicenter registry study was to investigate the effectiveness of ventilation tube insertion and the microbiology of otitis media with effusion (OME) in children. This part I study was conducted to evaluate the microbiological profile of children with OME who needed ventilation tube insertion. Methods: Patients <15 years old who were diagnosed as having OME and received ventilation tube insertion were prospectively enrolled in 16 tertiary hospitals from June 2014 to December 2016...
March 28, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29587128/direct-analysis-of-pathogenic-structures-affixed-to-the-tympanic-membrane-during-chronic-otitis-media
#15
Guillermo L Monroy, Wenzhou Hong, Pawjai Khampang, Ryan G Porter, Michael A Novak, Darold R Spillman, Ronit Barkalifa, Eric J Chaney, Joseph E Kerschner, Stephen A Boppart
Objective To characterize otitis media-associated structures affixed to the mucosal surface of the tympanic membrane (TM) in vivo and in surgically recovered in vitro samples. Study Design Prospective case series without comparison. Setting Outpatient surgical care center. Subjects and Methods Forty pediatric subjects scheduled for tympanostomy tube placement surgery were imaged intraoperatively under general anesthesia. Postmyringotomy, a portable optical coherence tomography (OCT) imaging system assessed for the presence of any biofilm affixed to the mucosal surface of the TM...
March 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29571277/tympanic-membrane-derived-stem-cell-like-cultures-for-tissue-regeneration
#16
Lawrence J Liew, Linda Q Chen, Allen Y Wang, Magnus von Unge, Marcus Atlas, Rodney J Dilley
Epidermal cells with stem cell-like characteristics have been identified in the tympanic membrane (TM) and localized specifically to the umbo and annulus regions. While they have been proposed to play a role in the regeneration of both acute and chronic tympanic membrane perforations, evidence for the mechanism and regulation of their contribution is not yet described. Indeed, the behaviour of these putative stem cells is largely unknown, in part due to a lack of refined methods for efficient cell isolation...
March 23, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29568876/fisetin-administration-improves-lps-induced-acute-otitis-media-in-mouse-in-vivo
#17
Peng Li, Dan Chen, Yang Huang
Acute otitis media is one of the most common infectious diseases worldwide in spite of the widespread vaccination. The present study was conducted to explore the effects of fisetin on mouse acute otitis media models. The animal models were established by lipopolysaccharide (LPS) injection into the middle ear of mice via the tympanic membrane. Fisetin was administered to mice for ten days through intragastric administration immediate after LPS application. Hematoxylin and eosin (H&E) staining was performed and the pro-inflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), IL-6 and VEGF, were measured through enzyme-linked immunosorbent assay (ELISA) method and RT-qPCR analysis...
March 22, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29566591/malignant-lymphoma-with-middle-ear-involvement-in-a-sprague-dawley-rat
#18
Jean-Francois Lafond, Annick Landry
Sprague-Dawley rats are amongst the most widely used animals in biomedical research and malignant lymphoma has long been known to be a frequent neoplasm in these animals. A 9-month-old male control Sprague-Dawley rat from a toxicity study showed gelatinous material in the cranial cavity and dark, thickened cerebral meninges at necropsy. At microscopic evaluation of the temporal bone, neoplastic lymphocytes were seen invading several structures of the middle ear. The neoplastic cells appeared to extend from the marrow of the temporal bone, covered the dorsal part of the tympanic cavity wall, and surrounded and infiltrated the base of the tensor tympani muscle as well as the chorda tympani branch of the facial nerve...
January 1, 2018: Laboratory Animals
https://www.readbyqxmd.com/read/29563067/paraquat-initially-damages-cochlear-support-cells-leading-to-anoikis-like-hair-cell-death
#19
Jianhui Zhang, Hong Sun, Richard Salvi, Dalian Ding
Paraquat (PQ), one of the most widely used herbicides, is extremely dangerous because it generates the highly toxic superoxide radical. When paraquat was applied to cochlear organotypic cultures, it not only damaged the outer hair cells (OHCs) and inner hair cells (IHCs), but also caused dislocation of the hair cell rows. We hypothesized that the dislocation arose from damage to the support cells (SCs) that anchors hair cells within the epithelium. To test this hypothesis, rat postnatal cochlear cultures were treated with PQ...
March 13, 2018: Hearing Research
https://www.readbyqxmd.com/read/29553522/a-surgical-procedure-for-the-administration-of-drugs-to-the-inner-ear-in-a-non-human-primate-common-marmoset-callithrix-jacchus
#20
Sho Kurihara, Masato Fujioka, Tomohiko Yoshida, Makoto Koizumi, Kaoru Ogawa, Hiromi Kojima, Hirotaka James Okano
Hearing research has long been facilitated by rodent models, although in some diseases, human symptoms cannot be recapitulated. The common marmoset (Callithrix jacchus) is a small, easy-to-handle New World monkey which has a similar anatomy of the temporal bone, including the middle ear ossicular chains and inner ear to humans, than in comparison with that of rodents. Here, we report a reproducible, safe, and rational surgical approach to the cochlear round window niche for the drug delivery to the inner ear of the common marmoset...
February 27, 2018: Journal of Visualized Experiments: JoVE
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