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https://www.readbyqxmd.com/read/28087416/the-path-of-a-click-stimulus-from-ear-canal-to-umbo
#1
Mario Milazzo, Elika Fallah, Michael Carapezza, Nina S Kumar, Jason H Lei, Elizabeth S Olson
The tympanic membrane (TM) has a key role in transmitting sounds to the inner ear, but a concise description of how the TM performs this function remains elusive. This paper probes TM operation by applying a free field click stimulus to the gerbil ear and exploring the consequent motions of the TM and umbo. Motions of the TM were measured both on radial tracks starting close to the umbo and on a grid distal and adjacent to the umbo. The experimental results confirmed the high fidelity of sound transmission from the ear canal to the umbo...
January 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/28087415/estimation-of-the-young-s-modulus-of-the-human-pars-tensa-using-in-situ-pressurization-and-inverse-finite-element-analysis
#2
S Alireza Rohani, Soroush Ghomashchi, Sumit K Agrawal, Hanif M Ladak
Finite-element models of the tympanic membrane are sensitive to the Young's modulus of the pars tensa. The aim of this work is to estimate the Young's modulus under a different experimental paradigm than currently used on the human tympanic membrane. These additional values could potentially be used by the auditory biomechanics community for building consensus. The Young's modulus of the human pars tensa was estimated through inverse finite-element modelling of an in-situ pressurization experiment. The experiments were performed on three specimens with a custom-built pressurization unit at a quasi-static pressure of 500 Pa...
January 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/28087317/acute-otitis-media-caused-by-streptococcus-pneumoniae-serotype-19a-st320-clone-epidemiological-and-clinical-characteristics
#3
Hsin Chi, Nan-Chang Chiu, Fu-Yuan Huang, Chyong-Hsin Hsu, Kuo-Sheng Lee, Li-Min Huang, Yu-Chia Hsieh
BACKGROUND: Streptococcus pneumoniae serotype 19A ST320, a highly multiresistant and virulent clone, has emerged as a common pathogen causing acute otitis media (AOM) in children. METHODS: Patients aged 0-18 years with AOM who presented at Mackay Memorial Hospital, Taipei, Taiwan were prospectively enrolled between December 1, 2009, and November 30, 2012. For each patient, a specimen of middle-ear fluid was obtained and cultured. S. pneumoniae isolates were tested by serotyping, antibiotic-resistance profiling, and multilocus sequence typing...
December 19, 2016: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28069080/role-of-circumferential-subannular-tympanoplasty-in-anterior-and-subtotal-perforations
#4
G B Singh, S Ranjan, R Arora, S Kumar
OBJECTIVE: This study aimed to evaluate the surgical success of a modified inlay tympanoplasty technique, known as circumferential subannular tympanoplasty, for anterior and subtotal perforations. METHODS: This prospective study was performed in a tertiary care teaching hospital between October 2013 and April 2016. A total of 58 adult patients of both sexes with anterior or subtotal perforations underwent circumferential subannular tympanoplasty under local anaesthesia...
January 10, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28057352/sigmoid-sinus-cortical-plate-dehiscence-induces-pulsatile-tinnitus-through-amplifying-sigmoid-sinus-venous-sound
#5
Shan Tian, Lizhen Wang, Jiemeng Yang, Rui Mao, Zhaohui Liu, Yubo Fan
Sigmoid sinus cortical plate dehiscence (SSCPD) is common in pulsatile tinnitus (PT) patients, and is treated through SSCPD resurfacing surgery in clinic, but the bio-mechanism is not clear as so far. This study aimed to clarify the bio-mechanism of PT sensation induced by SSCPD, and quantify the relationship of cortical plate (CP) thickness and PT sensation intensity. It was hypothesized that SSCPD would induce PT through significantly amplifying sigmoid sinus (SS) venous sound in this study. Finite element (FE) analysis based on radiology data of typical patient was used to verify this hypothesis, and was validated with clinical reports...
December 16, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28057076/audiometric-findings-with-voluntary-tensor-tympani-contraction
#6
Brandon Wickens, Duncan Floyd, Manohar Bance
BACKGROUND: Tensor tympani contraction may have a "signature" audiogram. This study demonstrates audiometric findings during voluntary tensor tympani contraction. METHODS: Five volunteers possessing the ability to voluntarily contract their tensor tympani muscles were identified and enrolled. Tensor tympani contraction was confirmed with characteristic tympanometry findings. Study subjects underwent conventional audiometry. Air conduction and bone conduction threshold testing was performed with and without voluntary tensor tympani contraction...
January 5, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28056979/malaria-epidemiology-in-central-myanmar-identification-of-a-multi-species-asymptomatic-reservoir-of-infection
#7
Isaac Ghinai, Jackie Cook, Teddy Tun Win Hla, Hein Myat Thu Htet, Tom Hall, Inke Nd Lubis, Rosanna Ghinai, Therese Hesketh, Ye Naung, Mya Mya Lwin, Tint Swe Latt, David L Heymann, Colin J Sutherland, Chris Drakeley, Nigel Field
BACKGROUND: The spread of artemisinin-resistant Plasmodium falciparum is a global health concern. Myanmar stands at the frontier of artemisinin-resistant P. falciparum. Myanmar also has the highest reported malaria burden in Southeast Asia; it is integral in the World Health Organization's plan to eliminate malaria in Southeast Asia, yet few epidemiological data exist for the general population in Myanmar. METHODS: This cross-sectional, probability household survey was conducted in Phyu township, Bago Region (central Myanmar), during the wet season of 2013...
January 5, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28052725/paracrine-activity-from-adipose-derived-stem-cells-on-in-vitro-wound-healing-in-human-tympanic-membrane-keratinocytes
#8
Huan Ting Ong, Sharon Redmond, Robert Marano, Marcus Atlas, Magnus von Unge, Peder Aabel, Rodney J Dilley
Stem cell therapies for tympanic membrane repair have shown initial experimental success using mesenchymal stem cells in rat models to promote healing, however the mechanisms providing this benefit are not known. We investigated in vitro the paracrine effects of human adipose-derived stem cells (ADSC) on wound healing mechanisms for human tympanic membrane-derived keratinocytes (hTM) and immortalised human keratinocytes (HaCat). ADSC conditioned media (CMADSC) were assessed for paracrine activity on keratinocyte proliferation and migration, with hypoxic conditions for ADSC culture used to generate contrasting effects on cytokine gene expression...
January 4, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28051987/traumatic-hearing-loss-in-the-context-of-blast-related-tympanic-membrane-perforation
#9
Max D Pusz, Jon Robitschek
OBJECTIVE: Identify associated clinical factors and characterize the various forms of hearing loss in the context of blast-related traumatic tympanic membrane (TM) perforation sustained in the combat setting. METHODS: A prospective study of 41 patients who sustained a TM perforation secondary to blast injury between 2010 and 2012 while serving in combat. Clinical examinations and audiograms were obtained for all patients by a single-institution Otolaryngology service with comparative data generated from review of pre and post-trauma hearing screens...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28045835/normative-wideband-reflectance-equivalent-admittance-at-the-tympanic-membrane-and-acoustic-stapedius-reflex-threshold-in-adults
#10
M Patrick Feeney, Douglas H Keefe, Lisa L Hunter, Denis F Fitzpatrick, Angela C Garinis, Daniel B Putterman, Garnett P McMillan
OBJECTIVES: Wideband acoustic immittance (WAI) measures such as pressure reflectance, parameterized by absorbance and group delay, equivalent admittance at the tympanic membrane (TM), and acoustic stapedius reflex threshold (ASRT) describe middle ear function across a wide frequency range, compared with traditional tests employing a single frequency. The objective of this study was to obtain normative data using these tests for a group of normal-hearing adults and investigate test-retest reliability using a longitudinal design...
December 30, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/28045591/clinical-practice-guideline-update
#11
Seth R Schwartz, Anthony E Magit, Richard M Rosenfeld, Bopanna B Ballachanda, Jesse M Hackell, Helene J Krouse, Claire M Lawlor, Kenneth Lin, Kourosh Parham, David R Stutz, Sandy Walsh, Erika A Woodson, Ken Yanagisawa, Eugene R Cunningham
Objective This update of the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation cerumen impaction clinical practice guideline provides evidence-based recommendations on managing cerumen impaction. Cerumen impaction is defined as an accumulation of cerumen that causes symptoms, prevents assessment of the ear, or both. Changes from the prior guideline include a consumer added to the development group; new evidence (3 guidelines, 5 systematic reviews, and 6 randomized controlled trials); enhanced information on patient education and counseling; a new algorithm to clarify action statement relationships; expanded action statement profiles to explicitly state quality improvement opportunities, confidence in the evidence, intentional vagueness, and differences of opinion; an enhanced external review process to include public comment and journal peer review; and 3 new key action statements on managing cerumen impaction that focus on primary prevention, contraindicated intervention, and referral and coordination of care...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28031155/an-implantable-hearing-system-as-rehabilitation-for-hearing-loss-due-to-bilateral-aural-atresia-surgical-technique-and-audiological-results
#12
Rubens de Brito, Luzia Maria Pozzobom Ventura, José Carlos Jorge, Eduardo Boaventura Oliveira, Luiz Fernando Manzoni Lourencone
OBJECTIVE: To demonstrate the surgical technique and audiological results of a middle ear implant for restoring hearing in patients with bilateral aural atresia and microtia with conductive or mixed hearing loss. MATERIALS AND METHODS: In this prospective study, 12 subjects aged 12 years and older presenting with hearing loss and bilateral congenital aural atresia underwent surgical insertion of a middle ear implant. The patients underwent tympanomastoidectomy with a wide opening of the attic and preservation of the roof of the atresic tympanic bone to expose the middle ear and position the floating mass transducer of the implant...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28031154/single-administration-of-a-sustained-release-formulation-of-kb-r7785-inhibits-tympanic-membrane-regeneration-in-an-animal-model
#13
Peter Luke Santa Maria, Chloe Santa Maria, Sungwoo Kim, Yunzhi Peter Yang
OBJECTIVE: A pressure equalization tube placed within the tympanic membrane is the only clinically available method for inhibiting tympanic membrane regeneration. Problems associated with this include associated otorrhea, biofilm formation, medial migration of the tube, tube retention, induction of granulation tissue, and a small but significant rate of cholesteatoma. We aimed to demonstrate that a single administration of a sustained-release polymer formulation of KB-R7785 maintains tympanic membrane perforation for at least 6 months...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28024609/mesenchymal-stem-cell-laden-hybrid-scaffold-for-regenerating-subacute-tympanic-membrane-perforation
#14
Chul Ho Jang, SeungHyun Ahn, Jae Whi Lee, Byeong Ha Lee, Hyeongjin Lee, GeunHyung Kim
Tympanic membrane (TM) perforation is one of the most common otology complications. To date, there has not been reported TM regeneration using bioprinted scaffold. The purpose of this study was to evaluate the efficacy and feasibility of bioprinted polycaprolactone/collagen/alginate-mesenchymal stem cell (PCAMSC) scaffolds for the regeneration of subacute TM perforation. Sprague-Dawley rats were used in an animal model of subacute TM perforation. In the experimental group (n=7), bioprinted 3D PCAMSC scaffold was placed on the perforation...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28017492/superior-canal-dehiscence-with-tegmen-defect-revealed-by-otoscopy-video-clip-demonstration-of-pulsatile-tympanic-membrane
#15
Andrea Castellucci, Cristina Brandolini, Gianluca Piras, Ignacio Javier Fernandez, Davide Giordano, Carmine Pernice, Giovanni Carlo Modugno, Antonio Pirodda, Gian Gaetano Ferri
Superior canal dehiscence is a pathologic condition of the otic capsule acting as aberrant window of the inner ear. It results in reduction of inner ear impedance and in abnormal exposure of the labyrinthine neuroepithelium to the action of the surrounding structures. The sum of these phenomena leads to the onset of typical cochleo-vestibular symptoms and signs. Among them, pulsatile tinnitus has been attributed to a direct transmission of intracranial vascular activities to labyrinthine fluids. We present the first video-otoscopic documentation of spontaneous pulse-synchronous movements of the tympanic membrane in two patients with superior canal dehiscence...
December 22, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28013421/measuring-core-temperature-using-the-proprietary-application-and-thermo-smartphone-adapter
#16
Tomasz Darocha, Jacek Majkowski, Tomasz Sanak, Paweł Podsiadło, Sylweriusz Kosiński, Kinga Sałapa, Piotr Mazur, Mirosław Ziętkiewicz, Robert Gałązkowski, Łukasz Krzych, Rafał Drwiła
Fast and accurate measurement of core body temperature is crucial for accidental hypothermia treatment. We have developed a novel light and small adapter to the headset jack of a mobile phone based on Android. It has been applied to measure temperature and set up automatic notifications (e.g. Global Positioning System coordinates to emergency services dispatcher, ECMO coordinator). Its validity was confirmed in comparison with Vital Signs Monitor Spacelabs Healthcare Elance 93300 as a reference method, in a series of 260 measurements in the temperature range of 10-42 °C...
December 24, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28011121/temporal-bone-paragangliomas-15-years-experience
#17
Mehmet Düzlü, Hakan Tutar, Recep Karamert, Furkan Karaloğlu, Muammer Melih Şahin, Mehmet Göcek, Mehmet Birol Uğur, Nebil Göksu
INTRODUCTION: Temporal bone paragangliomas (TBPs) are benign tumors arising from neural crest cells located along the jugular bulbus and the tympanic plexus. In general surgical excision, radiotherapy and wait-and-scan protocols are the main management modalities for TBPs. OBJECTIVE: In this paper we aim to present our clinical experience with TBPs and to review literature data. METHODS: The patients who were operated for tympanomastoid paraganglioma (TMP) or tympanojugular paraganglioma (TJP) in our clinic in the last 15 years were enrolled in the study...
December 8, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28005809/lipoma-of-the-tympanic-membrane
#18
Nurdoğan Ata, Tahir Bülbül, Betül Berberoğlu
No abstract text is available yet for this article.
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005796/tympanic-membrane-perforation-caused-by-thunderbolt-strike
#19
Nazim Bozan, Ahmet Faruk Kiroglu, Muzaffer Ari, Mahfuz Turan, Hakan Cankaya
Thunderbolt strike is a life-threatening entity. In the patients presenting with thunderbolt strike, the central nervous system and the cardiovascular system should be primarily evaluated, followed by tympanic membrane lesions. The most important symptom connected with ear is the loss of hearing. In this report, a 43-year-old male patient with unilateral tympanic membrane perforation, tinnitus, and bilateral sensorineural hearing loss caused by thunderbolt strike is presented through a review of the literature...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005742/aberrant-internal-carotid-artery-in-the-tympanic-cavity
#20
Rasim Yanmaz, Şemsettin Okuyucu, Gülen Burakgazi, Hanifi Bayaroğullari
OBJECTIVES: Presence of aberrant internal carotid artery (ICA) in the tympanic cavity is a very rare case and therefore the diagnosis is a challenge. Here, the authors aimed to address the importance of the diagnosis since the intervention to the middle ear and implants is increasing in number and this condition may lead to life-threatening bleeding. METHODS: Between 2012 and 2016, among the patients referred to the authors' Radiology Department from the Department of Otolaringology for the evaluation of the temporal region for various indications, the authors reported this anomaly in 6 patients and multidetector computerized tomography of these 6 patients and magnetic resonance imaging of 2 were assessed in detail...
November 2016: Journal of Craniofacial Surgery
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