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https://www.readbyqxmd.com/read/29145274/diagnosis-of-fetal-megacystis-with-chromosomal-abnormality-by-2d-prenatal-ultrasound-a-case-report
#1
Fuman She, Shengwen Dong, Bibo Yuan, Xiaoli Gao
RATIONALE: The pathogenesis of fetal megacystis is divided into obstructive and nonobstructive. Megacystis combined with chromosomal abnormalities is rare and most of the cases are nonobstructive. PATIENT CONCERNS: The fetus showed posterior urethral obstructive megacystis with features of bladder enlargement, "keyhole" feature, and thick bladder wall. DIAGNOSES: Here, we present a case of fetal megacystis diagnosed by ultrasound at pregnancy week 15+2 and with multisystem abnormalities...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29143107/how-i-do-it-endoscopic-microvascular-decompression-for-hemifacial-spasm-associated-with-the-vertebral-artery
#2
Fuminari Komatsu, Masaaki Imai, Mitsunori Matsumae
BACKGROUND: Microvascular decompression (MVD) of hemifacial spasm (HFS) associated with the vertebral artery (VA) shows higher rates of incomplete cure and complications compared to non-VA-related HFS. METHOD: Purely endoscopic MVD for VA-associated HFS via a retrosigmoid keyhole was performed. Neurovascular conflicts by a directly offending artery and VA around the root exit zone of the facial nerve were clearly demonstrated under 30° endoscopic view without significant cerebellar retraction...
November 15, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29138975/distal-transsylvian-keyhole-approach-for-unruptured-anterior-circulation-small-aneurysms
#3
Ririko Takeda, Hiroki Kurita
BACKGROUND: To reduce complications associated with conventional pterional craniotomy, a transsylvian keyhole approach for unruptured small anterior circulation aneurysms is proposed. METHODS: A 7-cm linear scalp incision is made along the hairline, beginning at the zygoma, followed by minimal temporal muscle dissection. Two burr holes are drilled out at McCarty's point and the temporal bone, and a 3-cm equilateral triangle bone flap is made, whose apex is located above the sylvian point...
November 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29134456/european-hernia-society-guidelines-on-prevention-and-treatment-of-parastomal-hernias
#4
REVIEW
S A Antoniou, F Agresta, J M Garcia Alamino, D Berger, F Berrevoet, H-T Brandsma, K Bury, J Conze, D Cuccurullo, U A Dietz, R H Fortelny, C Frei-Lanter, B Hansson, F Helgstrand, A Hotouras, A Jänes, L F Kroese, J R Lambrecht, I Kyle-Leinhase, M López-Cano, L Maggiori, V Mandalà, M Miserez, A Montgomery, S Morales-Conde, M Prudhomme, T Rautio, N Smart, M Śmietański, M Szczepkowski, C Stabilini, F E Muysoms
BACKGROUND: International guidelines on the prevention and treatment of parastomal hernias are lacking. The European Hernia Society therefore implemented a Clinical Practice Guideline development project. METHODS: The guidelines development group consisted of general, hernia and colorectal surgeons, a biostatistician and a biologist, from 14 European countries. These guidelines conformed to the AGREE II standards and the GRADE methodology. The databases of MEDLINE, CINAHL, CENTRAL and the gray literature through OpenGrey were searched...
November 13, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29126442/effect-of-enriched-housing-on-levels-of-natural-auto-antibodies-in-pigs-co-infected-with-porcine-reproductive-and-respiratory-syndrome-virus-prrsv-and-actinobacillus-pleuropneumoniae
#5
Lu Luo, Ingrid Daniëlle Ellen van Dixhoorn, Inonge Reimert, Bas Kemp, Jantina Elizabeth Bolhuis, Hendrik Karel Parmentier
Housing of pigs in barren, stimulus-poor housing conditions may influence their immune status, including antibody responses to (auto-)antigens, and thus affect immune protection, which will influence the onset and outcome of infection. In the present study, we investigated the effects of environmental enrichment versus barren housing on the level of natural (auto-)antibodies (NA(A)b) and their isotypes (IgM and IgG) binding keyhole limpet hemocyanin (KLH), myelin basic protein (MBP), and phosphorycholine conjugated to bovine serum albumin (PC-BSA) in pigs co-infected with porcine reproductive and respiratory syndrome virus (PRRSV) and Actinobacillus pleuropneumoniae (A...
November 10, 2017: Veterinary Research
https://www.readbyqxmd.com/read/29117242/the-keybox-shape-frame-fitting-during-tool-use-in-goffin-s-cockatoos-cacatua-goffiniana
#6
Cornelia Habl, Alice Marie Isabel Auersperg
The ability to move an object in alignment to a surface develops early in human ontogeny. However, aligning not just your own body but also the object itself in relation to a surface with a specific shape requires using landmarks rather than the own body as a frame of reference for orientation. The ability to do so is considered important in the development of tool use behaviour in human and non-human animals. Aside from humans, with the exception of a single study on habitually tool using primates, shape-frame matching abilities remain largely unstudied...
2017: PloS One
https://www.readbyqxmd.com/read/29115074/adapter-based-safety-injection-system-for-prevention-of-wrong-route-and-wrong-patient-medication-errors
#7
Yong Chan Cho, Seung Ho Lee, Yang Hyun Cho, Young Bin Choy
Wrong-route or -patient medication errors due to human mistakes have been considered difficult to resolve in clinical settings. In this study, we suggest a safety injection system that can help to prevent an injection when a mismatch exists between the drug and route or patient. For this, we prepared two distinct adapters with key and keyhole patterns specifically assigned to a pair of drug and route or patient. When connected to a syringe tip and its counterpart, a catheter injection-port, respectively, the adapters allowed for a seamless connection only with their matching patterns...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29114976/a-comparative-study-of-viral-capsids-and-bacterial-microcompartments-reveals-an-enriched-understanding-of-shell-dynamics
#8
Guang Song
In this work, we carry out a comparative study of the homo 360-mer structures of viral capsids and bacterial micro-compartments (MCPs). Different from viral 360-mers that all are arranged on a skewed right-handed icosahedral lattice with a triangulation number T of 7, the new 360-mer structure of AaLS-13, an engineered bacterial micro-compartment, offers a novel open conformation that has a unique unskewed lattice arrangement with a triangulation number T of 1 and large keyhole-shaped pores in the shell. By comparing their differences, we are able to predict a closed conformation of AaLS-13 that has the same lattice arrangement as existing viral capsid structures and in which all the keyhole-shaped pores are shut...
November 7, 2017: Proteins
https://www.readbyqxmd.com/read/29103840/the-influence-of-full-thickness-chondral-defects-on-outcomes-following-meniscal-allograft-transplantation-a-comparative-study
#9
Bryan M Saltzman, Maximilian A Meyer, Timothy S Leroux, Matthew E Gilelis, Margot Debot, Adam B Yanke, Brian J Cole
PURPOSE: To compare a series of patients who underwent meniscus allograft transplantation (MAT) with full-thickness chondral defects (FTD) with those with no chondral defect (ND) with regard to the following: change in patient-reported outcomes (PROs) from baseline to 2-year follow-up and baseline to the final follow-up (including comparisons to minimal clinically important differences), complications and complication rates, reoperations and reoperation rates/timing, and failures and time to failure (revision MAT or conversion to total knee arthroplasty)...
November 2, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29079224/a-new-species-of-proctoeces-and-reinstatement-of-proctoeces-humboldti-george-nascimento-and-quiroga-1983-digenea-fellodistomidae-based-on-molecular-and-morphological-evidence
#10
Marcelo E Oliva, Isabel M Valdivia, Leyla Cárdenas, Gabriela Muñoz, Ruben Escribano, Mario George-Nascimento
The most studied digenean of marine organisms in Chile is by far Proctoeces humboldti, a parasite of the intestine of the clingfish Sicyases sanguineus and gonad of the keyhole limpet Fissurella spp. (progenetic metacercariae). The mussel Perumytilus purpuratus has been suggested as the first intermediate host for this digenean. In a study examining the parasites of S. sanguineus from central Chile, we found specimens of Proctoeces showing significant morphological differences with P. humboldti. To assist in the resolution of the taxonomic identification of these specimens, as well sporocysts obtained from the mussel P...
October 24, 2017: Parasitology International
https://www.readbyqxmd.com/read/29062642/breast-reduction-decreasing-complications-and-improving-long-term-aesthetic-results-with-parenchymal-sutures
#11
Donald Anthony Hudson, Sean Moodley
BACKGROUND: The inverted T/keyhole pattern is commonly used for large breast reductions. This technique relies on the breast skin to retain the shape. With the passage of time "fallout" (pseudoptosis) occurs impairing the cosmetic result. A technique is described that uses parenchymal sutures and inframammary fold (IMF) reinforcement sutures to maintain the intraoperative shape. METHODS: A retrospective study of 25 consecutive patients (50 breasts) where the IMF was reinforced and parenchymal sutures were inserted...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29061321/robotic-parastomal-hernia-repair-with-biologic-mesh
#12
Peter Mekhail, Akbar Ashrafi, Mario Mekhail, David Hatcher, Monish Aron
INTRODUCTION: Parastomal hernia is a common and vexing problem after ileal conduit urinary diversion that can cause pain, bowel symptoms, and problems with the stoma appliance, resulting in leakage, odor, and impairment of quality of life. Historically, these hernias have been managed open surgically, which requires considerable dissection of the abdominal wall for mesh placement, and may also require relocating the stoma to the contralateral side. Further, open parastomal hernia repair can be a morbid procedure with recurrence rates of approximately 30%...
September 7, 2017: Urology
https://www.readbyqxmd.com/read/29055004/stat4-regulates-the-cd8-regulatory-t-cell-t-follicular-helper-cell-axis-and-promotes-atherogenesis-in-insulin-resistant-ldlr-mice
#13
Parésa L Taghavie-Moghadam, Tayab C Waseem, Julian Hattler, Lindsey M Glenn, Anca D Dobrian, Mark H Kaplan, Yi Yang, Roza Nurieva, Jerry L Nadler, Elena V Galkina
The metabolic syndrome and diabetic conditions support atherosclerosis, but the exact mechanisms for accelerated atherogenesis remain unclear. Although the proinflammatory role of STAT4 in atherosclerosis and diet-induced insulin resistance (IR) was recently established, the impact of STAT4 on atherogenesis in conditions of IR is not known. In this study, we generated Stat4(-/-)Ldlr(-/-) mice that were fed a diabetogenic diet with added cholesterol (DDC). DDC-fed Stat4(-/-)Ldlr(-/-) mice demonstrated improved glucose tolerance, insulin sensitivity, and a 36% reduction in atherosclerosis compared with Ldlr(-/-) controls...
November 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29053891/look-beyond-the-door-not-through-the-keyhole-evidence-from-a-cognitive-assessment-including-social-cognition-evaluation-in-multiple-sclerosis
#14
EDITORIAL
Antonio Carotenuto
Multiple sclerosis (MS) is a neurological disorder leading to both physical and cognitive disability in young adults. These limitations harshly impact the overall subject's habits and are predictive of poor social integration, resulting in reduced working activity and limited social network [1]. To this point, among the cognitive domains that could be impaired in MS, Social Cognition (SC) can have a direct impact on this outcome, due to its involvement in social interactions. This article is protected by copyright...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29040405/the-balcony-technique-of-breast-augmentation-and-inverted-t-mastopexy-with-an-inferior-dermoglandular-flap
#15
Roy de Vita, Giovanni Zoccali, Ernesto Maria Buccheri
Background: Optimal breast augmentation-mastopexy involves a reliable technique, fast recovery, minimal complications, and aesthetic results that are excellent and enduring. Objectives: The authors sought to determine whether the balcony technique of augmentation-mastopexy was safe and yielded satisfactory long-term outcomes in patients with breast ptosis and hypoplasia. Methods: The authors conducted a retrospective review of 207 patients who underwent subglandular augmentation and inverted-T mastopexy with a customized Wise keyhole resection pattern and an inferior flap...
October 16, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29040349/female-to-male-gender-affirming-top-surgery-a-single-surgeon-s-15-year-retrospective-review-and-treatment-algorithm
#16
Giancarlo McEvenue, Fang Zhou Xu, Runting Cai, Hugh McLean
Background: Mastectomy, referred to here as "Top Surgery," is an important surgical step for female-to-male (FTM) transgender patients. The goal is to excise breast tissue and create a masculine chest contour. Despite the rising demand for Top Surgery, debate still exists regarding how to select the most appropriate surgical technique to optimize aesthetic outcomes safely. Objectives: To determine the safety profile and aesthetic outcome of one surgeon's 15-year FTM Top Surgery experience...
July 24, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29027895/changes-in-foraminal-area-with-anterior-decompression-versus-keyhole-foraminotomy-in-the-cervical-spine-a-biomechanical-investigation
#17
Jacqueline Nguyen, Bryant Chu, Calvin C Kuo, Jeremi M Leasure, Christopher Ames, Dimitriy Kondrashov
OBJECTIVE Anterior cervical discectomy and fusion (ACDF) with or without partial uncovertebral joint resection (UVR) and posterior keyhole foraminotomy are established operative procedures to treat cervical disc degeneration and radiculopathy. Studies have demonstrated reliable results with each procedure, but none have compared the change in neuroforaminal area between indirect and direct decompression techniques. The purpose of this study was to determine which cervical decompression method most consistently increases neuroforaminal area and how that area is affected by neck position...
October 13, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28989048/supraorbital-keyhole-approach-to-the-sella-and-anterior-skull-base-via-a-forehead-wrinkle-incision
#18
Jin Xiao, Weihong Wang, Xianxiang Wang, Zhongxiang Mao, Hao Qi, Hongwei Cheng, Yongqiang Yu
OBJECTIVE: To evaluate safety and effectiveness of supraorbital keyhole approach to the sella and anterior skull base via a forehead wrinkle incision. METHODS: We analyzed and reclassified forehead wrinkle types in 100 recruited healthy individuals. Twenty patients with different intracranial lesions in the sella and anterior skull base areas were selected for surgery using the supraorbital keyhole approach via a forehead wrinkle incision by forehead wrinkle type...
October 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28982200/a-baculovirus-conjugated-mimotope-vaccine-targeting-mycobacterium-tuberculosis-lipoarabinomannan
#19
Hyun-Jin Shin, Luis H Franco, Vidhya R Nair, Angela C Collins, Michael U Shiloh
Mycobacterium tuberculosis, the causative agent of tuberculosis, is a major cause of morbidity and mortality worldwide. However, an effective vaccine for M. tuberculosis is lacking. We panned a phage display library using monoclonal antibodies against M. tuberculosis liporabinomannan (LAM), an important component of the M. tuberculosis cell wall, and identified two peptide sequences, HSFKWLDSPRLR or SGVYKVAYDWQH, with high antibody affinity after multiple rounds of panning. Only the HSFKWLDSPRLR peptide induced an anti-LAM response when conjugated to either keyhole limpet hemocyanin (KLH) or to the baculovirus Autographa californica multicapsid nucleopolyherovirus (AcMNPV) when introduced into mice by injection or via intranasal inoculation, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28958927/microscopic-minimally-invasive-keyhole-technique-for-surgical-resection-of-spinal-dumbbell-tumors
#20
Jie Xu, Chun-Hua Liu, Yuan Lin, Fen-Qi Luo
BACKGROUND: Multiple surgical modalities have been developedl and applied for surgical excision of spinal dumbbell tumors. The microscopic minimally invasive keyhole technique has not yet been well characterized for this purpose. We report our experience with 1-stage surgical resection of both intraforaminal and extraforaminal/paraspinal components of spinal dumbbell tumors using the microsurgical keyhole technique. METHODS: We retrospectively reviewed 12 cases of spinal dumbbell tumors treated via 1-stage surgical resection by the same senior spinal surgeon from January 2013 to April 2017...
September 27, 2017: World Neurosurgery
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