Manoj Limbraj Yellurkar, Vani Sai Prasanna, Pamelika Das, Sulogna Sarkar, Rakesh Matta, Devendra Kumar Dhaked, Ramalingam Peraman, Amit Kumar Taraphdar, Satheesh Kumar Nanjappan, Ravichandiran Velayutham, Somasundaram Arumugam
ETHNOPHARMACOLOGICAL RELEVANCE: Nonalcoholic fatty liver disease (NAFLD) is the most common severe liver disease globally, progressing further into nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). Vasaguduchyadi Kwatha (VK) is an Ayurvedic formulation traditionally used to treat liver diseases and other metabolic complications. This study is an ethnopharmacological approach to unravel this indigenous remedy. AIM OF THE STUDY: We aimed to discover the probable mechanism of action of VK against NASH in this study, using network pharmacology, molecular docking, in vitro study, and preclinical investigation...
May 23, 2024: Journal of Ethnopharmacology