Asmaa T Y Kishawy, Doaa Ibrahim, Elshimaa M Roushdy, Amira Moustafa, Fatma Eldemery, Elham M Hussein, Fardos A M Hassan, Sara T Elazab, Mohamed Tharwat Elabbasy, Raheela Kanwal, Walid M Kamel, Mohamed R Atteya, Asmaa W Zaglool
Climate change is considered to be the primary cause of heat stress (HS) in broiler chickens. Owing to the unique properties of extracted polyphenols, resveratrol-loaded liposomal nanoparticles (Resv-Lipo NPs) were first explored to mitigate the harmful effects of HS. The dietary role of Resv-Lipo NPs in heat-stressed birds was investigated based on their growth performance, antioxidative potential, and the expression of heat shock proteins, sirtuins, antioxidant, immune, and muscle-building related genes. A total of 250 1-day-old Ross 308 broiler chickens were divided into five experimental groups (5 replicates/group, 10 birds/replicate) for 42 days as follows: the control group was fed a basal diet and reared in thermoneutral conditions, and the other four HS groups were fed a basal diet supplemented with Resv-Lipo NPsI, II, and III at the levels of 0, 50, 100, and 150 mg/kg diet, respectively...
2023: Frontiers in Veterinary Science