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https://www.readbyqxmd.com/read/29411045/-health%C3%A2-4-0-how-are-we-doing-tomorrow
#1
REVIEW
Markus Müschenich, Laura Wamprecht
Digitization in healthcare is progressing steadily. While currently processes are being optimized and processes are being facilitated, the breakthrough of digital medicine is still forthcoming. Digital medicine includes applications that focus on the patient and give them the promise of better care. Many digital health applications are raising attention in traditional healthcare, as they are increasingly showing evidence.This report discusses the question of the impact of digital health applications on healthcare in the near future by evaluating the effect of software used to improve diagnosis, therapy and the communication between patients and healthcare professionals...
February 6, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29334953/care-relationships-at-stake-home-healthcare-professionals-experiences-with-digital-medicine-dispensers-a-qualitative-study
#2
Sigrid Nakrem, Marit Solbjør, Ida Nilstad Pettersen, Hanne Hestvik Kleiven
BACKGROUND: Although digital technologies can mitigate the burdens of home healthcare services caused by an ageing population that lives at home longer with complex health problems, research on the impacts and consequences of digitalised remote communication between patients and caregivers is lacking. The present study explores how home healthcare professionals had experienced the introduction of digital medicine dispensers and their influence on patient-caregiver relationships. METHODS: The multi-case study comprised semi-structured interviews with 21 healthcare professionals whose home healthcare service involved using the digital medicine dispensers...
January 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29316626/merging-digital-medicine-and-economics-two-moving-averages-unlock-biosignals-for-better-health
#3
Mohamed Elgendi
Algorithm development in digital medicine necessitates ongoing knowledge and skills updating to match the current demands and constant progression in the field. In today's chaotic world there is an increasing trend to seek out simple solutions for complex problems that can increase efficiency, reduce resource consumption, and improve scalability. This desire has spilled over into the world of science and research where many disciplines have taken to investigating and applying more simplistic approaches. Interestingly, through a review of current literature and research efforts, it seems that the learning and teaching principles in digital medicine continue to push towards the development of sophisticated algorithms with a limited scope and has not fully embraced or encouraged a shift towards more simple solutions that yield equal or better results...
January 6, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29285753/biobanks-in-the-era-of-digital-medicine
#4
Gunnar Jacobs, Andreas Wolf, Michael Krawczak, Wolfgang Lieb
Digitalization is currently permeating virtually all sectors of modern societies, including biomedical research and medical care. At the same time, biobanks engaged in the long-term storage of biological samples that are fit for purpose have become key drivers in both fields. The present article highlights some of the challenges and opportunities that biobanking is facing in the current proverbial "era of digitalization."
December 29, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29243960/what-can-behavioral-healthcare-learn-from-digital-medicine
#5
Brenda K Wiederhold
No abstract text is available yet for this article.
December 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29224260/-ten-years-retrospective-review-of-the-application-of-digital-medical-technology-in-general-surgery-in-china
#6
C H Fang, Y Y Lau, W P Zhou, W Cai
Digital medical technology is a powerful tool which has forcefully promoted the development of general surgery in China. In this article, we reviews the application status of three-dimensional visualization and three-dimensional printing technology in general surgery, introduces the development situation of surgical navigation guided by optical and electromagnetic technology and preliminary attempt to combined with mixed reality applied to complicated hepatectomy, looks ahead the development direction of digital medicine in the era of artificial intelligence and big data on behalf of surgical robot and radiomics...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29224259/-expert-consensus-of-precise-diagnosis-and-treatment-for-pancreatic-head-cancer-using-three-dimensional-visualization-technology
#7
(no author information available yet)
Three-dimensional (3D) visualization technology in pancreatic head cancers could offer decision-making support to preoperative diagnosis, resectability assessment and individualized surgical planning. In addition, the pancreas 3D printing helps to realize the leapfrog development from 3D images to 3D physical models and provides better guidance of the precise surgery of complicated cancers of the pancreatic head. In order to standardize the application of 3D visualization and 3D printing technology in the diagnosis and treatment of pancreatic head cancer, Chinese experts in relevant fields were organized by four committees to formulate this expert consensus...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29153081/risks-and-benefits-of-twitter-use-by-hematologists-oncologists-in-the-era-of-digital-medicine
#8
REVIEW
Deanna J Attai, Patricia F Anderson, Michael J Fisch, David L Graham, Matthew S Katz, Jennifer Kesselheim, Merry Jennifer Markham, Nathan A Pennell, Mina S Sedrak, Michael A Thompson, Audun Utengen, Don S Dizon
Twitter use by physicians, including those in the hematology-oncology field, is increasing. This microblogging platform provides a means to communicate and collaborate on a global scale. For the oncology professional, an active Twitter presence provides opportunities for continuing medical education, patient engagement and education, personal branding, and reputation management. However, because Twitter is an open, public forum, potential risks such as patient privacy violations, personal information disclosures, professionalism lapses, and time management need to be considered and managed...
October 2017: Seminars in Hematology
https://www.readbyqxmd.com/read/29089771/a-multicenter-open-label-pilot-study-evaluating-the-functionality-of-an-integrated-call-center-for-a-digital-medicine-system-to-optimize-monitoring-of-adherence-to-oral-aripiprazole-in-adult-patients-with-serious-mental-illness
#9
Alex Kopelowicz, Ross A Baker, Cathy Zhao, Claudette Brewer, Erica Lawson, Timothy Peters-Strickland
BACKGROUND: Medication nonadherence is common in the treatment of serious mental illness (SMI) and leads to poor outcomes. The digital medicine system (DMS) objectively measures adherence with oral aripiprazole in near-real time, allowing recognition of adherence issues. This pilot study evaluated the functionality of an integrated call center in optimizing the use of the DMS. MATERIALS AND METHODS: An 8-week, open-label, single-arm trial at four US sites enrolled adults with bipolar I disorder, major depressive disorder, and schizophrenia on stable oral aripiprazole doses and willing to use the DMS (oral aripiprazole + ingestible event marker [IEM], IEM-detecting skin patch, and software application)...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29081149/-effect-of-simulating-leg-length-inequality-on-spinal-and-pelvic-posture-in-the-elderly
#10
H F Zhang, J L Liao, M Ji, S Y Tang, J F Jin, L Chen, L J Wu
Objective: To study the effects of simulating leg length inequality on the spine and pelvic posture in standing and walking states and to explore their compensatory laws. Methods: From January to April, a total of 44 healthy volunteers were rasterstereographically examined for spine and pelvis in Institute of Digitized Medicine, Wenzhou Medical University and Department of Orthopaedics, First Affiliated Hospital of Wenzhou Medical University.Volunteers wore uniform shoes, and single 5 mm thick insoles were customized...
October 24, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29058219/lemrg-decision-rule-generation-algorithm-for-mining-microrna-expression-data
#11
Łukasz Piątek, Jerzy W Grzymała-Busse
Recently, research on mining microRNA (or miRNA) expression data has received a lot of attention, mainly because of its role in gene regulation. However, such type of data - usually saved in the form of microarrays - are very specific, because they contain only a small number of cases (often less than 100) compared with large number of attributes (equal to several hundreds or even tens of thousand). The small number of cases available during the learning process can cause instability of the newly created classifiers...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29042823/digital-health-technology-for-use-in-patients-with-serious-mental-illness-a-systematic-review-of-the-literature
#12
REVIEW
Sonal Batra, Ross A Baker, Tao Wang, Felicia Forma, Faith DiBiasi, Timothy Peters-Strickland
BACKGROUND: As the capabilities and reach of technology have expanded, there is an accompanying proliferation of digital technologies developed for use in the care of patients with mental illness. The objective of this review was to systematically search published literature to identify currently available health technologies and their intended uses for patients with serious mental illness. MATERIALS AND METHODS: The Medline, Embase, and BIOSIS Previews electronic databases were searched to identify peer-reviewed English language articles that reported the use of digital, mobile, and other advanced technology in patients with schizophrenia/schizoaffective disorder, bipolar disorder, and major depressive disorder...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29027665/impact-of-digital-technologies-on-novel-endpoint-capture-in-clinical-trials
#13
Ieuan Clay
Digital technologies have been successfully deployed in clinical settings for many years, yet recent advances in hardware and analytic capabilities have driven an explosion in interest over the potential of digital medicine to change how drugs are developed, centering on how we interact with patients, treat patients, and capture information about patients.
December 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28952822/recent-advances-in-the-molecular-diagnosis-of-polycystic-kidney-disease
#14
Carsten Bergmann
Polycystic kidney disease (PKD) is clinically and genetically heterogeneous and constitutes the most common heritable kidney disease. Most patients are affected by the autosomal dominant form (ADPKD) which generally is an adult-onset multisystem disorder. By contrast, the rarer recessive form ARPKD usually already manifests perinatally or in childhood. In some patients, however, ADPKD and ARPKD can phenotypically overlap with early manifestation in ADPKD and only late onset in ARPKD. Progressive fibrocystic renal changes are often accompanied by severe hepatobiliary changes or other extrarenal abnormalities...
November 16, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28797726/progress-in-digital-medicine
#15
EDITORIAL
Zheng-Guo Wang, Liang Zhang, Wen-Jun Zhao
No abstract text is available yet for this article.
July 14, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28732101/the-conundrum-of-digital-medicine
#16
EDITORIAL
David A Fisher
No abstract text is available yet for this article.
July 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28698169/effectiveness-of-digital-medicines-to-improve-clinical-outcomes-in-patients-with-uncontrolled-hypertension-and-type-2-diabetes-prospective-open-label-cluster-randomized-pilot-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
Juan Frias, Naunihal Virdi, Praveen Raja, Yoona Kim, George Savage, Lars Osterberg
BACKGROUND: Hypertension and type 2 diabetes mellitus are major modifiable risk factors for cardiac, cerebrovascular, and kidney diseases. Reasons for poor disease control include nonadherence, lack of patient engagement, and therapeutic inertia. OBJECTIVE: The aim of this study was to assess the impact on clinic-measured blood pressure (BP) and glycated hemoglobin (HbA1c) using a digital medicine offering (DMO) that measures medication ingestion adherence, physical activity, and rest using digital medicines (medication taken with ingestible sensor), wearable sensor patches, and a mobile device app...
July 11, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28597911/digitizing-medicines-for-remote-capture-of-oral-medication-adherence-using-co-encapsulation
#18
Sara H Browne, Charles Peloquin, Frank Santillo, Richard Haubrich, Leticia Muttera, Kathleen Moser, George Savage, Constance Benson, Terrence Blaschke
High-resolution measurement of medication adherence is essential to personalized drug therapy . An FDA-cleared device, using an edible ingestion sensor (IS), external wearable patch and paired mobile device, can detect and record ingestion events. Oral medications must be combined with an IS to generate precise 'digitized-medication' ingestion records. We developed a GMP-protocol to repackage oral medications with the IS within certified Capsugel® capsules, termed co-encapsulation (CoE). A randomized bioequivalence study of CoE-IS-Rifamate (Isoniazid/Rifampin 150/300mg) versus native-Rifamate was conducted in 12 patients with active Mycobacterium Tuberculosis (MTB) and demonstrated bioequivalence using the population method ratio test (95% CI)...
June 9, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28597138/advances-in-renal-genetic-diagnosis
#19
REVIEW
Carsten Bergmann
Most genetic disorders are clinically and genetically heterogeneous. Next-generation sequencing (NGS) has revolutionized the field and is providing rapidly growing insights into the pathomechanism of hereditary nephropathies. Current best-practice guidelines for most hereditary nephropathies include genetic diagnostics. The increasing number of genes that have to be considered in patients with hereditary nephropathies is often challenging when addressed by conventional techniques and largely benefits from NGS-based approaches that allow the parallel analysis of all disease genes in a single test at relatively low cost, e...
July 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28590335/technological-methods-to-measure-adherence-to-antiretroviral-therapy-and-preexposure-prophylaxis
#20
Lindsey E Garrison, Jessica E Haberer
PURPOSE OF REVIEW: The WHO's Consolidated Guidelines (2016) call for research on improved methods to proactively monitor adherence and identify those individuals who have the greatest needs for adherence support. This review aims to elucidate the latest technologies available to measure adherence to HIV antiretroviral therapy and preexposure prophylaxis against HIV infection and present their utility in various settings and populations. RECENT FINDINGS: Within the last few years, advances have been made in the features of existing technology to measure adherence (real-time electronic adherence measurements), additional approaches have been developed (digital medicine systems) and improved (short message service surveys), and point of care testing for pharmacokinetic measures are under development...
September 2017: Current Opinion in HIV and AIDS
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