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Abdominal adhesions

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https://www.readbyqxmd.com/read/28635173/laparoscopic-surgery-for-sigmoid-colon-cancer-after-multiple-operations-including-urinary-diversion-with-indiana-pouch-a-case-report
#1
Kazuya Iwamoto, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
A 73-year-old man with lower abdominal pain was diagnosed at our hospital with sigmoid colon cancer. He had previously undergone radical cystectomy with Indiana pouch construction and gastrectomy to treat bladder cancer and gastric cancer, respectively. We performed a laparoscopic Hartmann's operation with Japanese D3 lymph node dissection. We observed severe adhesion in the abdominal cavity; adhesions between the urostomy and sigmoid colon were particularly severe. The tumor had invaded to the distal rectum, which had adhered to the pubic bone and the previously reconstructed urinary pouch...
June 21, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28628674/hepatic-microvascular-dysfunction-and-increased-advanced-glycation-end-products-are-components-of-non-alcoholic-fatty-liver-disease
#2
Evelyn Nunes Goulart da Silva Pereira, Raquel Rangel Silvares, Edgar Eduardo Ilaquita Flores, Karine Lino Rodrigues, Isalira Peroba Ramos, Igor José da Silva, Marcelo Pelajo Machado, Rosiane Aparecida Miranda, Carmen Cabanelas Pazos-Moura, Cassiano F Gonçalves-de-Albuquerque, Hugo Caire de Castro Faria-Neto, Eduardo Tibiriça, Anissa Daliry
BACKGROUND: This study aimed to investigate the pathophysiology of hepatic microcirculatory dysfunction in non-alcoholic fatty liver disease (NAFLD). METHODS: In Wistar rats, NAFLD model was induced by 20 weeks of high-fat diet (HFD) feeding. Rolling and adhesion of leukocytes and tissue perfusion in hepatic microcirculation were examined using in vivo microscopic and laser speckle contrast imaging (LSCI), respectively. Oxidative stress and inflamatory parameters were analysed by TBARs, catalase enzyme activity, RT-PCR and ELISA...
2017: PloS One
https://www.readbyqxmd.com/read/28624050/impact-of-hospital-volume-on-outcomes-for-laparoscopic-adhesiolysis-for-small-bowel-obstruction
#3
Raymond A Jean, Kathleen M O'Neill, Kevin Y Pei, Kimberly A Davis
BACKGROUND: Volume-to-outcome data have been studied in several complex surgical procedures, demonstrating improved outcomes at higher volume centers. Laparoscopic lysis of adhesions (LLOA) for small bowel obstruction (SBO) may result in better outcomes, but there is no information on the learning curve for this potentially complex case. This study evaluates the effect of institutional procedural volume on length of stay (LOS), outcomes, and costs in LLOA for SBOs. MATERIALS AND METHODS: The Nationwide Inpatient Sample data set between 2000 and 2013 was queried for discharges for a diagnosis of SBO involving LLOA in adult patients...
June 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28618654/comparison-of-honey-and-dextrose-solution-on-post-operative-peritoneal-adhesion-in-rat-model
#4
Vafa Baradaran Rahimi, Reza Shirazinia, Narges Fereydouni, Parvin Zamani, Sousan Darroudi, Amir Hossein Sahebkar, Vahid Reza Askari
BACKGROUND: Peritoneal adhesion between abdominal organs is a complication of surgery. It causes major complications like pain, bowel obstruction, infertility and increases risk of death. Honey is known to have anti-inflammatory and antioxidant properties potentially relevant for adhesive protection. METHODS: Thirty rats were divided into five groups: negative control without any surgical procedure (normal group), control group treated with normal saline, experimental group I treated with 1ml of 10% honey, experimental group II treated with honey at half concentration of group I (honey0...
June 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28601319/a-carboxymethylcellulose-heparin-combination-for-the-prevention-of-surgical-adhesions
#5
James R Docherty, P Aiden McCormick
BACKGROUND: Adhesions are a major clinical problem after abdominal surgery. Despite decades of research, therapies to prevent adhesion formation are suboptimal. MATERIALS AND METHODS: We have investigated combinations of carboxymethylcellulose (CMC) and heparin at preventing surgical adhesions in two rat models of adhesion formation. The first was the well-established cecal abrasion model, and the second was a model developed in our laboratory, the avascular mesenteric knot model...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28601230/the-effects-of-pirfenidone-on-t-helper-cells-in-prevention-of-intraperitoneal-adhesions
#6
Kemal Ozbilgin, Melis Aylin Üner, Mahmud Ozkut, Pinar Solmaz Hasdemir
Abdominal surgery is linked with peritoneal adhesions. We investigated that the anti-fibrotic agent pirfenidone (PFD) has immune modulating activities and evaluated its effects on the function of T helper type 1 (Th1), Th2 and T regulatory (Treg) cells, which may play important roles in peritoneal adhesions. Eighteen female Wistar rats underwent right-sided parietal peritoneal and right uterine horn adhesion model. Rats were randomized into 3 groups as group 1 (control) (closure of midline abdominal incision without any agent administrations), group 2 (closure of incision after intraperitoneal administration of PFD) and group 3 (closure of incision and only oral administration of PFD for 14 days)...
June 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28597677/endoscopic-management-of-afferent-loop-syndrome-caused-by-enteroliths-and-anastomotic-stricture-a-case-report
#7
Ana Rita Alves, Nuno Almeida, Margarida Ferreira, Luís Tomé
Afferent loop syndrome (ALS) is a rare complication of Billroth-II gastrojejunostomy. Causes of afferent loop obstruction include adhesions, internal hernias, intestinal strictures or malignancy. Obstruction caused by enteroliths is rare and usually requires surgery. We present the case of a 90-year-old man with a Billroth-II performed 50 years earlier and three acute pancreatitis. He presented with acute abdominal pain, without signs of pancreatitis. Upper digestive endoscopy revealed a punctiform anastomotic stricture of the afferent loop...
June 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28594257/mri-evaluation-of-an-elastic-tpu-mesh-under-pneumoperitoneum-in-ipom-position-in-a-porcine-model
#8
A Lambertz, L C L van den Hil, A Ciritsis, R Eickhoff, N A Kraemer, N D Bouvy, A Müllen, U Klinge, U P Neumann, C D Klink
BACKGROUND: The frequency of laparoscopic approaches increased in hernia surgery over the past years. After mesh placement in IPOM position, the real extent of the meshes configurational changes after termination of pneumoperitoneum is still largely unknown. To prevent a later mesh folding it might be useful to place the mesh while it is kept under tension. Conventionally used meshes may lose their Effective Porosity under these conditions due to poor elastic properties. The aim of this study was to evaluate a newly developed elastic thermoplastic polyurethane (TPU) containing mesh that retains its Effective Porosity under mechanical strain in IPOM position in a porcine model...
June 8, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28589045/recurrent-enterolithiasis-small-bowel-obstruction-a-case-seldom-described
#9
Ashish Lal Shrestha, Pradita Shrestha
BACKGROUND: Enterolithiasis of the small bowel is a rare phenomenon in humans although it has been frequently described in equines. Primary enteroliths have been described including those occurring secondary to conditions like Crohn's disease, small bowel diverticula, tuberculous or postoperative strictures, and blind loops but those occurring in an otherwise normal gut are exceedingly rare. Of even greater rarity is a recurrent small bowel enterolith presenting with obstruction. This may be the first report of such kind...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28584681/abdominal-pseudocyst-as-a-complication-of-ventriculoperitoneal-shunt-placement-review-of-the-literature-and-a-proposed-algorithm-for-treatment-using-4-illustrative-cases
#10
Samir Kashyap, Hammad Ghanchi, Tanya Minasian, Fanglong Dong, Dan Miulli
BACKGROUND: Ventriculoperitoneal (VP) shunt placement is one of the most commonly performed procedures in neurosurgery. One rare complication is the formation of an abdominal pseudocyst, which can cause shunt malfunction. CASE DESCRIPTIONS: We present four unique cases of abdominal pseudocyst formation. Our first patient initially presented with a right upper quadrant pseudocyst. Shunt was externalized and the distal end was revised with placement of catheter on the opposite side...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28581895/safety-and-efficacy-of-alginate-adhesion-barrier-gel-in-compromised-intestinal-anastomosis
#11
Ankit A Chaturvedi, Simon T K Yauw, Roger M L M Lomme, Thijs Hendriks, Harry van Goor
BACKGROUND: For any anti-adhesive barrier developed for abdominal surgery, the use under conditions in which anastomotic healing is compromised needs to be investigated. The current study evaluates the effect of a new ultrapure alginate gel on early healing of high-risk anastomoses in the ileum and compares this with the gold standard used in clinical practice. MATERIALS AND METHODS: In 75 adult male Wistar rats, a 5 mm ileal segment was resected and continuity was restored by construction of an inverted anastomosis...
June 5, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28578700/a-rare-presentation-of-an-acute-abdomen-an-ileal-diverticular-perforation
#12
Basuru Uvindu Thilakawardana, Sanjay De Mel, Vasitha Abeysuriya, Janaki Hewavisenthi, Chandima De Mel, Lal Chandrasena, Visula Abeysuriya
BACKGROUND: This case report highlights the value of prompt intervention of diagnostic laparoscopy in a patient suspects of having an acute abdomen due to an intestinal perforation, where there is a limitation of performing Contrast Enhanced Computed Tomography of abdomen. A previously healthy young adult presenting with an acute abdomen due to a spontaneous ileal perforation, without any associated risk factors is a rare clinical entity in a developing country. Therefore, entertaining an early diagnosis will possibly prevent a fatal consequence...
June 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28576076/prevention-of-intra-abdominal-adhesion-using-electrospun-peg-plga-nanofibrous-membranes
#13
Jian Li, Jinhui Zhu, Ting He, Weida Li, Yue Zhao, Zaomei Chen, Junhui Zhang, Huaying Wan, Rubing Li
The use of physical barriers, such as nanofiber membranes, is a potential method to prevent adhesion formation after surgery. In this study, we fabricated electrospun composite poly(ethylene glycol) (PEG)/poly(lactic-co-glycolic) (PLGA) nanofibrous membrane to prevent abdomen adhesion; this composite acts as a barrier between cecum and the surrounding tissues without interrupting mass transfer and cecum healing. PEG/PLGA nanofibrous membranes consisting of 0% (P0), 5% (P1), 10% (P2), 15% (P3), 20% (P4), and 25% (P5) PEG were prepared, and their physicochemical properties were characterized...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28571995/is-peritoneal-dialysis-feasible-after-laparotomy-in-children-a-case-control-series-to-compare-outcomes
#14
A Bouty, A Faure, L Shaw, J Ah Toy, E Dobremez, M O'Brien, Y Heloury
OBJECTIVES: Peritoneal dialysis (PD) is the modality of choice for children with end-stage renal disease (ESRD) awaiting renal transplant; however, this option is sometimes avoided for those with previous laparotomy. The goal of this study was to compare the outcomes of PD in patients with and without previous laparotomy. PATIENTS AND METHODS: Twenty-four patients who had been started on peritoneal dialysis were retrospectively analysed. Group LAP consisted of six patients with previous laparotomy, and Group NO-LAP of 18 controls with either retroperitoneal or no abdominal surgery...
May 12, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28560023/malrotation-with-midgut-volvulus-in-an-adult-a-case-report-and-review-of-the-literature
#15
Adrian T Fung, David E Konkin, Zaheer S Kanji
We report a case of a 53-year-old male who presented with acute onset right upper quadrant (RUQ) abdominal pain with investigations demonstrating malrotation causing midgut volvulus and subsequent intestinal obstruction. The patient was consented for an emergent operation and underwent an exploratory laparotomy. Operative findings included the presence of adhesive bands in the RUQ (Ladd's Band), volvulus of the mid-portion of the small bowel in a clockwise fashion and multiple intra-abdominal adhesions causing internal hernias...
May 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28557204/anti-adhesive-effects-of-a-newly-developed-two-layered-gelatin-sheet-in-dogs
#16
Hiroko Torii, Toshitaka Takagi, Mamoru Urabe, Hiroyuki Tsujimoto, Yuki Ozamoto, Hiroe Miyamoto, Yoshihito Ikada, Akeo Hagiwara
AIM: Adhesion after pelvic surgery causes infertility, ectopic pregnancy, and ileus or abdominal pain. The materials currently available for clinical use are insufficient. The purpose of this study was to develop an anti-adhesive material that overcomes the limitations of conventional anti-adhesive agents. METHODS: The adhesion prevention effects of three methods - a two-layered sheet composed of gelatin film and gelatin sponge, Seprafilm and INTERCEED - were evaluated in 37 dogs...
May 29, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28550915/evaluation-of-four-mesh-fixation-methods-in-an-experimental-model-of-ventral-hernia-repair
#17
Grigoris Chatzimavroudis, Stylianos Kalaitzis, Nikolaos Voloudakis, Stefanos Atmatzidis, Spyridon Kapoulas, Ioannis Koutelidakis, Basilis Papaziogas, Emmanouil C Christoforidis
BACKGROUND: The present animal study was conducted to comparably investigate the performance of four different fixation techniques of intraperitoneally implanted meshes. MATERIALS AND METHODS: Fifteen New Zealand white rabbits were used. In each animal, four abdominal wall defects were created and repaired with four pieces of intraperitoneal mesh (Parietex Composite), fixed with nonabsorbable (titanium) spiral tacks (group A), absorbable (lactic and glycolic acid co-polymer) screw-type tacks (group B), transfascial polypropylene sutures (group C), or fibrin glue (group D)...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28549396/molecular-mechanisms-underlying-the-protective-effects-of-hydrogen-saturated-saline-on-noise-induced-hearing-loss
#18
Liwei Chen, Mingkun Han, Yan Lu, Daishi Chen, Xuejun Sun, Shiming Yang, Wei Sun, Ning Yu, Suoqiang Zhai
OBJECTIVES: This study aimed to explore the molecular mechanism of the protective effects of hydrogen-saturated saline on NIHL. METHODS: Guinea pigs were divided into three groups: hydrogen-saturated saline; normal saline; and control. For saline administration, the guinea pigs were given daily abdominal injections 3 d before and 1 h before noise exposure. ABR were tested to examine cochlear physiology changes. The changes of 8-hydroxy-desoxyguanosine (8-HOdG), interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), intercellular cell adhesion molecule-1 (ICAM-1) and high mobility group box-1 protein (HMGB1) in the cochlea were also examined...
May 26, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28547932/from-intraperitoneal-onlay-mesh-repair-to-preperitoneal-onlay-mesh-repair
#19
REVIEW
George Pei Cheung Yang
Laparoscopic repair for ventral and incisional hernias was first reported in the early 1990s. It uses intraperitoneal only mesh placement to achieve a tension-free repair of the hernia. However, in recent years, there has been greater concern about long-term complication involving intraperitoneal mesh placement. Many case reports and case series have found evidence of mesh adhesion, mesh fistulation, and mesh migration into hollow organs including the esophagus, small bowel, and large bowel, resulting in various major acute abdominal events...
May 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28545230/nanog-plays-a-hierarchical-role-in-the-transcription-network-regulating-the-pluripotency-and-plasticity-of-adipose-tissue-derived-stem-cells
#20
Maria Pitrone, Giuseppe Pizzolanti, Laura Tomasello, Antonina Coppola, Lorenzo Morini, Gianni Pantuso, Romina Ficarella, Valentina Guarnotta, Sebastio Perrini, Francesco Giorgino, Carla Giordano
The stromal vascular cell fraction (SVF) of visceral and subcutaneous adipose tissue (VAT and SAT) has increasingly come into focus in stem cell research, since these compartments represent a rich source of multipotent adipose-derived stem cells (ASCs). ASCs exhibit a self-renewal potential and differentiation capacity. Our aim was to study the different expression of the embryonic stem cell markers NANOG (homeobox protein NANOG), SOX2 (SRY (sex determining region Y)-box 2) and OCT4 (octamer-binding transcription factor 4) and to evaluate if there exists a hierarchal role in this network in ASCs derived from both SAT and VAT...
May 23, 2017: International Journal of Molecular Sciences
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