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aggressive periodontitis

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https://www.readbyqxmd.com/read/29456312/long-term-effect-of-lactobacillus-brevis-cd2-inersan-%C3%A2-and-or-doxycycline-in-aggressive-periodontitis
#1
Mishal Piyush Shah, Sheela Kumar Gujjari, Veerendrakumar Siddhpur Chandrasekhar
Context: The over usage and broad use of antibiotics resulted in the emergence of resistant microorganisms to the drugs which also disturb the indigenous microflora, which include the Lactobacillus in the oral cavity. Hence, it is preferred to avoid the use of antibiotics. Aims: The hypothesis tested in this study was that 14 days of treatment with Lactobacillus brevis CD2 lozenges, L. brevis CD2 with oral doxycycline, or doxycycline alone would have a beneficial effect on periodontal health after 5 months...
July 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29451591/impact-of-aggressive-periodontitis-and-chronic-periodontitis-on-oral-health-related-quality-of-life
#2
Alexandre Hugo Llanos, Carlos Guillermo Benítez Silva, Karina Tamie Ichimura, Estela Sanches Rebeis, Marcela Giudicissi, Marcelo Munhóes Romano, Luciana Saraiva
The purpose of this cross-sectional study was to investigate the effect of different forms of periodontal diseases on Oral Health-Related Quality of Life (OHRQoL). Fifty-two patients with Aggressive Periodontitis (AP) or Chronic Periodontitis (CP) were included: nine patients with Localized Aggressive Periodontitis (LAP), thirty-three patients with Generalized Aggressive Periodontitis (GAP) and ten patients with Generalized Chronic Periodontitis (GCP). Oral Health Impact Profile questionnaires (OHIP-14) were distributed after a clinical examination that measured the following periodontal parameters: tooth loss, bleeding on probing (BoP), probing depth (PD), gingival recession (REC) and clinical attachment level (CAL)...
2018: Brazilian Oral Research
https://www.readbyqxmd.com/read/29449347/association-of-tumor-necrosis-factor-%C3%AE-tnf-%C3%AE-gene-promoter-polymorphisms-with-aggressive-and-chronic-periodontitis-in-eastern-indian-population
#3
Poulami Majumder, Keheibamding Thou, Mandar Bhattacharya, Vineet Nair, Sujay Ghosh, Subrata Kumar Dey
Periodontitis is a very common inflammatory oral disease. Tumor necrosis factor α (TNF-α), a cytokine has been involved with the gingival tissue destruction and remodeling occurrence. We aimed at investigation of the association of single nucleotide polymorphisms (SNPs) in TNF-α gene promoter region to the susceptibility of aggressive and chronic periodontitis in eastern Indian population. A total of 397 DNA samples from venous blood have been isolated, among them 40 individuals were aggressive periodontitis patient, 157 were identified chronic periodontitis patients and remaining 200 were healthy individuals...
February 15, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29429231/-combined-periodontal-orthodontic-treatment-and-nine-year-follow-up-of-a-patient-with-generalized-aggressive-periodontitis-a-case-report
#4
L H Lei, H J Hu, Y Y Yu, J Z Xie, W L Sun
No abstract text is available yet for this article.
February 9, 2018: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29415708/il-13-1112-polymorphism-and-periodontitis-susceptibility-a-meta-analysis
#5
Wenbo Zhang, Pu Xu, Zhuogeng Chen, Yanan Cheng, Xiaoni Li, Qiuhua Mao
BACKGROUND: Several studies have examined the association between the IL-13 -1112C/T polymorphism and the risk of periodontitis. However, these studies have reached different conclusions. The aim of the current study was to investigate the link between this IL-13 -1112 polymorphism and susceptibility to periodontitis. METHODS: We utilized electronic databases, including the CNKI (China National Knowledge Infrastructure), Wanfang, PubMed, Embase, and Cochrane Library databases, to manually search for relevant research published through November 30, 2016...
February 7, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29411112/treatment-of-intrabony-defects-with-modified-perforated-membranes-in-aggressive-periodontitis-a-12-month-randomized-controlled-trial
#6
Bartłomiej Górski, Stanisław Jalowski, Renata Górska, Maciej Zaremba
OBJECTIVE: The aim of this study was to compare the clinical and radiographic efficacy of guided tissue regeneration with a modified perforated collagen membrane (MPM) or standard collagen membrane (CM) in the treatment of intrabony defects in patients with aggressive periodontitis (AgP). MATERIALS AND METHODS: Fifteen AgP patients were included in the study. Two single intrabony defects of at least 3 mm depth with ≥ 6 mm probing pocket depth (PPD) from each patient were randomly assigned to either xenogenic graft plus MPM (test group) or xenogenic graft plus CM (control group)...
February 6, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29405147/profiling-of-aggregatibacter-actinomycetemcomitans-serotypes-b-and-c-and-the-genotypes-in-periodontal-health-and-disease
#7
Swati Setty, Tanvee Wadikar, S S Suprith, Kishore Bhat, Srinath Thakur
BACKGROUND: A. actinomycetemcomitans is prevalent in periodontitis but is found in some periodontally healthy individuals as well. Certain serotypes of the organism have shown to determine severity of the disease. The distribution of serotype and genotype is affected by geographic and ethnic variation. Therefore, the present study was aimed to detect serotypes b & c of A. actinomycetemcomitans and the genotypes and find its correlation with periodontal status. MATERIALS AND METHODS: A total of 75 subjects (25 aggressive periodontitis, 25 chronic periodontitis and 25 periodontally healthy) in age range of 14-55 yrs were included...
October 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29398863/comprehensive-rehabilitation-using-dental-implants-in-generalized-aggressive-periodontitis
#8
Asha Ramesh, Sheethalan Ravi, Gurumoorthy Kaarthikeyan
Generalized aggressive periodontitis (GAP) is a debilitating form of the disease and it results in deteriorating effects on the esthetic and functional aspects of the oral cavity. This case report describes the comprehensive rehabilitation of GAP patient using dental implants. The treatment planning involved thorough scaling and root planning (SRP) with oral hygiene instructions. The patient was motivated to adhere to a strict oral hygiene regimen following which periodontal flap surgery employing guided tissue regeneration and bone grafts was performed...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29363676/diagnosis-of-aggressive-periodontitis-a-dilemma
#9
Raisa Queiroz Catunda, Liran Levin, Ida Kornerup, Monica Prasad Gibson
Periodontitis is one of the leading causes of tooth loss in the adult population. This disease can be classified into various categories, and one of the most destructive amongst them is aggressive periodontitis (AgP). The incidence of AgP is lower than other types of periodontitis. However, it affects young individuals and can cause severe destruction of tooth-supporting structures including tooth loss if left untreated. The current classification for diagnosing periodontal disease was established by the American Academy of Periodontology (AAP) in 1999...
January 22, 2018: Quintessence International
https://www.readbyqxmd.com/read/29332208/localised-aggressive-periodontitis-in-a-3-year-old-boy
#10
E Mass, F Hershkovitz, U Zilberman
BACKGROUND: Localised aggressive periodontitis (LAgP), characterised by rapid attachment and bone loss, which may occur in children and adolescents, without clinical evidence of systemic disease. CASE REPORT: Three-year-old boy was referred with excessive mobility of 83 and exfoliation of 73. Clinical examination revealed acceptable oral hygiene. Blood tests were performed to evaluate PMNs activity and the parents were advised to apply 0.2% chlorhexidine twice a day...
January 13, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29331511/maresin-1-regulates-autophagy-and-inflammation-in-human-periodontal-ligament-cells-through-glycogen-synthase-kinase-3%C3%AE-%C3%AE-catenin-pathway-under-inflammatory-conditions
#11
Li Du, Yucheng Li, Weifeng Liu
OBJECTIVE: Accumulating lines of evidence suggest that maresin 1 (MaR-1) exerts anti-inflammatory effects in many cell types and plays beneficial roles in inflammatory disease, such as peritonitis and colitis. Moreover, it has been demonstrated that MaR-1 play protective roles against localized aggressive periodontitis. However, the function and mechanism of MaR-1 in human periodontal ligament cells (PDL) cells from periodontitis are poorly understood. The present study aimed to clarify the effects and molecular mechanism of MaR-1 in PDL cell survival and inflammation...
December 23, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29326511/differential-diagnosis-between-chronic-versus-aggressive-periodontitis-and-staging-of-aggressive-periodontitis-a-cross-sectional-study
#12
Srinivas Sulugodu Ramachandra, Vivek Vijay Gupta, Dhoom Singh Mehta, Kalyan C Gundavarapu, Nibali Luigi
Background: Differentiating between chronic periodontitis (CP) and aggressive periodontitis (AgP) is challenging. The aim of this study was to assess the variations in diagnosis between CP versus AgP and the staging of AgP based on the disease-staging index for AgP among periodontists, specialists in oral medicine, and general dental practitioners (GDPs). Materials and Methods: Fifteen cases diagnosed as either CP or AgP were included in a "case document" and sent electronically to 75 respondents...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29318966/chronic-inflammatory-diseases-and-atherosclerotic-cardiovascular-disease-innocent-bystanders-or-partners-in-crime
#13
Peter Riis Hansen
Inflammation plays a significant role in atherosclerosis and cardiovascular disease (CVD). Patients with chronic inflammatory diseases are at increased risk of CVD, but it is debated whether this association is causal or dependent on shared risk factors, other exposures, genes, and/or inflammatory pathways. The current review summarizes epidemiological, clinical, and experimental data supporting the role of shared inflammatory mechanisms between atherosclerotic CVD and rheumatoid arthritis, psoriasis, inflammatory bowel disease, and periodontitis, respectively, and provides insights to future prospects in this area of research...
January 9, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29306716/risk-factors-affecting-the-prognosis-of-descending-necrotizing-mediastinitis-from-odontogenic-infection
#14
Luyao Qu, Xiang Liang, Bin Jiang, Wentao Qian, Weijie Zhang, Xieyi Cai
PURPOSE: Descending necrotizing mediastinitis (DNM) is a serious complication of head and neck infections and has an excessively high mortality rate owing to the lack of understanding of DNM. We assessed the clinical characteristics, diagnosis, treatment, and outcomes of odontogenic DNM and evaluated the risk factors affecting the prognosis of DNM to provide an up-to-date overview for clinical practice. MATERIALS AND METHODS: We performed a retrospective cohort study, enrolling a sample of patients with DNM due to odontogenic infection who had been referred from January 2013 to December 2016...
December 13, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29299190/evaluation-of-microbiota-associated-with-herpesviruses-in-active-sites-of-generalized-aggressive-periodontitis
#15
Claudio Passariello, Pierangelo Gigola, Luca Testarelli, Monica Puttini, Serena Schippa, Stefano Petti
Aims: The present study aimed to investigate microbial patterns associated with disease progression and coinfection by different Herpesviruses in generalized aggressive periodontitis (GAP). Methods: Microbiological samples were obtained from active (AS) and non-active (n-AS) sites in 165 subjects affected by GAP and were analyzed for 40 bacterial species by the Checkerboard DNA-DNA Hybridization technique and for Herpes simplex 1 (HSV-1), Human Cytomegalovirus (CMV), and Epstein Bar virus (EBV) by PCR...
April 2017: Annali di Stomatologia
https://www.readbyqxmd.com/read/29284977/rehabilitation-of-anterior-maxilla-with-dental-implants-in-periodontally-compromised-patient
#16
D Manikandan, V R Balaji, R Lamobodharan, R Mahalakshmi
Although implant is the treatment of choice for rehabilitation of patients with aggressive periodontitis, it is also challenging for the dentists. There are various views about success of implant therapy for these patients. Few authors have proposed that aggressive periodontitis patients have less success rate of implant survival, while many authors have shown successful management of aggressive periodontitis patients with implants. For implants to be successful in these patient, it is important to control the periodontal disease before placement of implants...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29279825/ct-evaluation-of-underlying-bone-sclerosis-in-patients-with-oral-squamous-cell-carcinoma-a-preliminary-retrospective-study
#17
Gyu-Dong Jo, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee, Soon-Chul Choi, Kyung-Hoe Huh
Purpose: Underlying bone sclerosis is frequently observed in clinical settings when oral squamous cell carcinoma (OSCC) invades the jaw bone. The aim of this study was to assess the prevalence and characteristics of underlying bone sclerosis in patients with OSCC. Materials and Methods: We retrospectively reviewed the computed tomographic (CT) images of 131 patients who underwent mandibulectomy between January 2012 and December 2015 to treat OSCC. The presence, degree, and extent of underlying bone sclerosis were assessed on CT images and correlated with the following imaging patterns of bone invasion: cortical invasion, medullary invasion with a smooth margin, and medullary invasion with an irregular margin...
December 2017: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/29276776/periodontitis-in-ch%C3%A3-diak-higashi-syndrome-an-altered-immunoinflammatory-response
#18
V Thumbigere Math, P Rebouças, P A Giovani, R M Puppin-Rontani, R Casarin, L Martins, L Wang, K Krzewski, W J Introne, M J Somerman, F H Nociti, K R Kantovitz
Chédiak-Higashi syndrome (CHS), a rare autosomal recessive disorder caused by mutations in the lysosomal trafficking regulator gene (LYST), is associated with aggressive periodontitis. It is suggested that LYST mutations affect the toll-like receptor (TLR)-mediated immunoinflammatory response, leading to frequent infections. This study sought to determine the periodontal status of patients with classic (severe) and atypical (milder) forms of CHS and the immunoregulatory functions of gingival fibroblasts in CHS patients...
January 2018: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/29243487/assessing-a-multiplex-targeted-proteomics-approach-for-the-clinical-diagnosis-of-periodontitis-using-saliva-samples
#19
Brenda Mertens, Valérie Orti, Jérôme Vialaret, Philippe Gibert, Aroa Relaño-Ginés, Sylvain Lehmann, Dominique Deville de Périère, Christophe Hirtz
AIM: The present study focused on the research of new biomarkers based on the liquid chromatography-multiple-reaction monitoring (MRM) proteomic profile in whole saliva of patients with periodontitis compared with periodontal healthy patients. METHODS: A 30-min multiplexed liquid chromatography-MRM method was used for absolute quantification of 35 plasma biomarkers in saliva from control patients and patients with periodontitis. RESULTS: Three proteins namely hemopexin, plasminogen and α-fibrinogen were shown to be clearly related to the presence of periodontitis compared with healthy patients...
December 15, 2017: Bioanalysis
https://www.readbyqxmd.com/read/29229732/utilization-of-variant-and-fusion-proteins-to-functionally-map-the-aggregatibacter-actinomycetemcomitans-trimeric-autotransporter-protein-apia
#20
Carla Cugini, Yongyi Mei, David Furgang, Nisha George, Narayanan Ramasubbu, Daniel H Fine
The Gram-negative bacterium Aggregatibacter actinomycetemcomitans is a causative agent of localized aggressive periodontitis. Critical to its infection process is the first and essential step of attachment, which is related to the coordinated functions of surface components comprised of proteins and extracellular polysaccharides. One such protein is the outer membrane trimeric autotransporter protein ApiA, a versatile virulence factor with numerous functions including cell binding, invasion, serum resistance, autoaggregation, and induction of cytokine release...
December 11, 2017: Infection and Immunity
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