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https://www.readbyqxmd.com/read/29140152/trend-analysis-of-20-years-of-fim-road-racing-grand-prix-motorcycle-world-championship
#1
Emanuele D'Artibale, Maheswaran Rohan, John B Cronin
BACKGROUND/AIM: The technological advancements in motorcycle road racing have ensured the evolution of motorcycle performance, however, it is unknown whether these advancements have resulted in increased speed and therefore risk. To better understand the top level of this sport and inform future regulations, performance-related strategies and safety procedures, this study aims at: 1) analysing and describing how the performance characteristics of the top-class of the FIM Grand Prix motorcycle world championship have changed with time; and, 2) quantifying potential interactions between performance data (i...
November 15, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29135638/mountain-biking-injuries
#2
Majid Ansari, Ruhollah Nourian, Morteza Khodaee
With the increasing popularity of mountain biking, also known as off-road cycling, and the riders pushing the sport into extremes, there has been a corresponding increase in injury. Almost two thirds of acute injuries involve the upper extremities, and a similar proportion of overuse injuries affect the lower extremities. Mountain biking appears to be a high-risk sport for severe spine injuries. New trends of injury patterns are observed with popularity of mountain bike trail parks and freeride cycling. Using protective gear, improving technical proficiency, and physical fitness may somewhat decrease the risk of injuries...
November 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29112626/effects-of-ad-libitum-low-carbohydrate-high-fat-dieting-in-middle-age-male-runners
#3
Alexander J Heatherly, Lauren G Killen, Ashton F Smith, Hunter S Waldman, Angela Hollingsworth, Christie L Seltmann, Eric K O'Neal
PURPOSE: This study examined the effects of a 3-week ad libitum high fat (~70% of calories), low carbohydrate (<50 g/day) diet (LCHF) on markers of endurance performance in middle-aged, recreationally competitive male runners. METHODS: All subjects (n = 8) following their normal HC diet had anthropometric measures assessed and completed 5, 10-min running bouts at multiple individual race paces in the heat while physiological, metabolic variables and perceptual responses were recorded...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29109686/ketone-diester-ingestion-impairs-time-trial-performance-in-professional-cyclists
#4
Jill J Leckey, Megan L Ross, Marc Quod, John A Hawley, Louise M Burke
We investigated the effect of pre- "race" ingestion of a 1,3-butanediol acetoacetate diester on blood ketone concentration, substrate metabolism and performance of a cycling time trial (TT) in professional cyclists. In a randomized cross-over design, 10 elite male cyclists completed a ~31 km laboratory-based TT on a cycling ergometer programmed to simulate the 2017 World Road Cycling Championships course. Cyclists consumed a standardized meal [2 g/kg body mass (BM) carbohydrate (CHO)] the evening prior to a trial day and a CHO breakfast (2 g/kg BM CHO) with 200 mg caffeine on the morning of a trial day...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29067854/sex-and-age-related-differences-in-half-marathon-performance-and-competitiveness-in-the-world-s-largest-half-marathon-the-g%C3%A3-teborgsvarvet
#5
B Knechtle, P T Nikolaidis
In road runners, the age-related performance decline has been well investigated for marathoners, but little is known for half-marathoners. We analysed data from 138,616 runners (48,148 women and 90,469 men) competing between 2014 and 2016 in GöteborgsVarvet, the world's largest half-marathon. The men-to-women ratio in participants increased with age, the fastest race times were observed in age groups ˂35 and 35-39 years in women and in age group 35-39 years in men, the main effect of sex and the sex × age group interaction on race time were trivial, and the competitiveness was denser in men and in the younger age groups...
October 25, 2017: Research in Sports Medicine
https://www.readbyqxmd.com/read/28961410/overcoming-the-host-immune-response-to-adeno-associated-virus-gene-delivery-vectors-the-race-between-clearance-tolerance-neutralization-and-escape
#6
REVIEW
Federico Mingozzi, Katherine A High
Immune responses in gene therapy with adeno-associated virus (AAV) vectors have been the object of almost two decades of study. Although preclinical models helped to define and predict certain aspects of interactions between the vector and the host immune system, most of our current knowledge has come from clinical trials. These studies have allowed development of effective interventions for modulating immunotoxicities associated with vector administration, resulting in therapeutic advances. However, the road to full understanding and effective modulation of immune responses in gene therapy is still long; the determinants of the balance between tolerance and immunogenicity in AAV vector-mediated gene transfer are not fully understood, and effective solutions for overcoming preexisting neutralizing antibodies are still lacking...
September 29, 2017: Annual Review of Virology
https://www.readbyqxmd.com/read/28806276/circulating-progenitor-cell-response-to-exercise-in-wheelchair-racing-athletes
#7
Grace M Niemiro, Thomas Edwards, J P Barfield, Joseph W Beals, Elizabeth M Broad, Robert W Motl, Nicholas A Burd, Lara A Pilutti, Michael De Lisio
INTRODUCTION: Circulating progenitor cells (CPCs) are a heterogeneous population of stem/progenitor cells in peripheral blood that participate in tissue repair. CPC mobilization has been well characterized in able-bodied persons, but has not been previously investigated in wheelchair racing athletes. The purpose of this study was to characterize CPC and CPC sub-population mobilization in elite wheelchair racing athletes in response to acute, upper-extremity aerobic exercise to determine if CPC responses are similar to ambulatory populations...
August 11, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28798038/infographics-winning-road-cycle-races-a-team-sky-perspective
#8
EDITORIAL
Neil Heron, Richard Usher, Derick MacLeod, Inigo Sarrieguil, Juan Mercadel, Mark A Tully
No abstract text is available yet for this article.
August 10, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28746232/the-effect-of-topical-thiocolchicoside-in-preventing-and-reducing-the-increase-of-muscle-tone-stiffness-and-soreness-a-real-life-study-on-top-level-road-cyclists-during-stage-competition
#9
Marco Gervasi, Davide Sisti, Piero Benelli, Eneko Fernández-Peña, Cinzia Calcabrini, Marco B L Rocchi, Luigi Lanata, Michela Bagnasco, Andrea Tonti, Stocchi Vilberto, Piero Sestili
In professional road cyclists, the majority of overuse injuries affect the lower limbs and are mostly represented by contractures or muscle shortening, characterized by an increase of tone and stiffness and a variation of elasticity. Treatment and prevention of these specific conditions may include physical, supplementary, and pharmacologic support. The aim of this real-life study was to determine: first, the alterations of tone, stiffness, elasticity, and soreness of rectus femoris (RF) and biceps femoris (BF) in top class cyclists engaged in 3 multistage races, and second, whether any variable in the management of the athletes may affect the prevention and/or reduction of such alterations...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28707561/profiling-the-physical-load-on-riders-of-top-level-motorcycle-circuit-racing
#10
Emanuele D'Artibale, Paul B Laursen, John B Cronin
Manoeuvring a motorcycle at high-speed in official competition has been shown to expose riders to substantial and complex physiological and psychological demands, however few studies have analysed the physical load experienced by professional racers. This study aimed to quantify the physical stress experienced by riders and explore relationships between performance related variables (i.e. crashes). Performance and braking data were collected from official race reports from 2013 to 2015 of the top class of the FIM Road Racing Grand Prix World Championship...
July 14, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28701100/intervention-analysis-of-the-safety-effects-of-a-legislation-targeting-excessive-speeding-in-canada
#11
Suliman A Gargoum, Karim El-Basyouny
Excessive speeding is a major traffic safety concern consequently, numerous countermeasures have been considered to mitigate this problem. Excessive speeding, street racing and stunt driving activities subject all road users to extreme risk. To address this problem, three Canadian provinces introduced severe sanctions against drivers who exceed speed limits by high margins. Under the laws offenders were subject to immediate license suspension and vehicle impoundment. In this paper, intervention analysis of the collision data from the three provinces was conducted to identify the safety effects of the legislation...
July 13, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28700517/longitudinal-assessment-of-bone-mineral-density-and-body-composition-in-competitive-cyclists
#12
Breanne S Baker, Raoul F Reiser
Baker, BS and Reiser II, RF. A longitudinal assessment of bone mineral density and body composition in competitive cyclists. J Strength Cond Res 31(11): 2969-2976, 2017-Competitive cycling has been associated with low bone mineral density (BMD); however, BMD is a multifaceted issue. The purpose of this study was to investigate how age (18-49 years), sex, USA Cycling Category (elite-4), and racing type (road and multiple bikes), influenced body composition across a season in competitive cyclists. February marked the preseason, where 42 participants (22 males, 20 females) completed a health history and cycling questionnaire, 4-day dietary log and a dual-energy X-ray absorptiometry scan, and repeated the measures 180 ± 11 days later...
November 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28669689/effects-of-erythropoietin-on-cycling-performance-of-well-trained-cyclists-a-double-blind-randomised-placebo-controlled-trial
#13
Jules A A C Heuberger, Joris I Rotmans, Pim Gal, Frederik E Stuurman, Juliëtte van 't Westende, Titiaan E Post, Johannes M A Daniels, Matthijs Moerland, Peter L J van Veldhoven, Marieke L de Kam, Herman Ram, Olivier de Hon, Jelle J Posthuma, Jacobus Burggraaf, Adam F Cohen
BACKGROUND: Substances that potentially enhance performance (eg, recombinant human erythropoietin [rHuEPO]) are considered doping and are therefore forbidden in sports; however, the scientific evidence behind doping is frequently weak. We aimed to determine the effects of rHuEPO treatment in well trained cyclists on maximal, submaximal, and race performance and on safety, and to present a model clinical study for doping research on other substances. METHODS: We did this double-blind, randomised, placebo-controlled trial at the Centre for Human Drug Research in Leiden (Netherlands)...
August 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28547345/where-are-adults-active-an-examination-of-physical-activity-locations-using-gps-in-five-us-cities
#14
Katelyn M Holliday, Annie Green Howard, Michael Emch, Daniel A Rodríguez, Wayne D Rosamond, Kelly R Evenson
Increasing physical activity (PA) at the population level requires appropriately targeting intervention development. Identifying the locations in which participants with various sociodemographic, body weight, and geographic characteristics tend to engage in varying intensities of PA as well as locations these populations underutilize for PA may facilitate this process. A visual location-coding protocol was developed and implemented in Google Fusion Tables and Maps using data from participants (N = 223, age 18-85) in five states...
August 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28542090/5-km-time-trial-reliability-of-a-non-motorized-treadmill-and-comparison-of-physiological-and-perceptual-responses-versus-a-motorized-treadmill
#15
Hunter S Waldman, Alex J Heatherly, Ashton F Waddell, Ben M Krings, Eric K O'Neal
This study examined the reproducibility of performance across 3 non-motorized treadmill (NMT) 5-km time trials (TT) and physiological, gait, and perceptual differences of running at 5-km pace for both NMT and motorized treadmills (MT). Ten male runners experienced in road racing that had never run on a NMT completed 3 TT to establish personal best 5-km pace. In a later session, participants ran at this pace for 5 min on the NMT while metabolic, gait, and perceptual measures were recorded and then ran at outdoor 5-km personal best pace on a MT at 1% grade (counter-balanced crossover design)...
May 24, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28525454/bilateral-tibial-osteofibrous-dysplasia-on-18f-fdg-pet-ct
#16
Hiroaki Nagano, Megumi Jinguji, Masanori Nakajo, Michiyo Higashi, Takashi Yoshiura
A 17-year-old girl had pain in the right front lower leg while road racing 2 months earlier. Radiography and CT showed osteolytic lesions in the medial part of the bilateral tibia. Bone scintigraphy showed focally increased radiotracer uptake in the bilateral tibia. The lesions showed hypermetabolism on FDG PET/CT. Osteofibrous dysplasia was suspected from the radiographic findings, but adamantinoma or metastases could not be excluded. Surgical biopsies were performed, and histopathologic studies confirmed the diagnosis of bilateral osteofibrous dysplasia...
August 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28499425/hand-held-cell-phone-use-while-driving-legislation-and-observed-driver-behavior-among-population-sub-groups-in-the-united-states
#17
COMPARATIVE STUDY
Toni M Rudisill, Motao Zhu
BACKGROUND: Cell phone use behaviors are known to vary across demographic sub-groups and geographic locations. This study examined whether universal hand-held calling while driving bans were associated with lower road-side observed hand-held cell phone conversations across drivers of different ages (16-24, 25-59, ≥60 years), sexes, races (White, African American, or other), ruralities (suburban, rural, or urban), and regions (Northeast, Midwest, South, and West). METHODS: Data from the 2008-2013 National Occupant Protection Use Survey were merged with states' cell phone use while driving legislation...
May 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28445214/teaching-the-social-determinants-of-health-a-path-to-equity-or-a-road-to-nowhere
#18
Malika Sharma, Andrew D Pinto, Arno K Kumagai
Medical schools are increasingly called to include social responsibility in their mandates. As such, they are focusing their attention on the social determinants of health (SDOH) as key drivers in the health of the patients and communities they serve. However, underlying this emphasis on SDOH is the assumption that teaching medical students about SDOH will lead future physicians to take action to help achieve health equity. There is little evidence to support this belief. In many ways, the current approach to SDOH within medical education positions the SDOH as "facts to be known" rather than as "conditions to be challenged and changed...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28424267/using-a-novel-data-resource-to-explore-heart-rate-during-mountain-and-road-running
#19
Andrew Best, Barry Braun
Online, accessible performance and heart rate data from running competitions are posted publicly or semi-publicly to social media. We tested the efficacy of one such data resource- Strava- as a tool in exercise physiology investigations by exploring heart rate differences in mountain racing and road racing running events. Heart rate and GPS pace data were gathered from Strava activities posted by 111 males aged 21-49, from two mountain races (Mt. Washington Road Race and Pike's Peak Ascent) and two road race distances (half marathon and marathon)...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28282753/reliability-of-the-virtual-elevation-method-to-evaluate-rolling-resistance-of-different-mountain-bike-cross-country-tyres
#20
Thomas Maier, Beat Müller, Lucas Schmid, Thomas Steiner, Jon Peter Wehrlin
Although a low rolling resistance is advantageous in mountain bike cross-country racing, no studies have used the virtual elevation method to compare tyres from different manufacturers as used in international competitions so far. The aims of this study were to assess the reliability of this method, to compare the off-road rolling resistance between tyres and to calculate the influence on off-road speed. Nine 29-in. mountain bike cross-country tyres were tested on a course representing typical ground surface conditions 5 or 6 times...
February 9, 2017: Journal of Sports Sciences
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