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https://www.readbyqxmd.com/read/28293767/gambling-in-a-national-u-s-veteran-population-prevalence-socio-demographics-and-psychiatric-comorbidities
#1
Elina A Stefanovics, Marc N Potenza, Robert H Pietrzak
This study aimed to examine associations between gambling level and clinically relevant measures, including psychiatric disorders and suicidality, in a nationally representative sample of U.S. veterans. Data on 3157 U.S. veterans were analyzed from the National Health and Resilience in Veterans Study. Chi square tests and analyses of variance were used to assess associations between gambling level, and demographic, military, and personality characteristics. Multinomial logistic regressions using stepwise selection were used to identify independent correlates of recreational gambling and at-risk/problem gambling (ARPG)...
March 14, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/28286627/subcutaneous-interferon-%C3%AE-1a-administration-by-electronic-auto-injector-is-associated-with-high-adherence-in-patients-with-relapsing-remitting-multiple-sclerosis-in-a-real-life-study
#2
Elina Järvinen, Juha Multanen, Sari Atula
The objective was to investigate adherence measured by an electronic auto-injector device, and self-reported adherence and treatment convenience in subjects with relapsing remitting multiple sclerosis (RRMS), using an electronic auto-injector Rebismart(®) to self-inject interferon β-1a. Thirty one patients with RRMS using the electronic auto-injector Rebismart(®) for self-injecting interferon β-1a subcutaneously three times weekly were included in a real-life clinical multicenter study for 24 weeks in Finland...
February 20, 2017: Neurology International
https://www.readbyqxmd.com/read/28283612/self-reported-mental-health-problems-among-adults-born-preterm-a-meta-analysis
#3
REVIEW
Riikka Pyhälä, Elina Wolford, Hannu Kautiainen, Sture Andersson, Peter Bartmann, Nicole Baumann, Ann-Mari Brubakk, Kari Anne I Evensen, Petteri Hovi, Eero Kajantie, Marius Lahti, Ryan J Van Lieshout, Saroj Saigal, Louis A Schmidt, Marit S Indredavik, Dieter Wolke, Katri Räikkönen
CONTEXT: Preterm birth increases the risk for mental disorders in adulthood, yet findings on self-reported or subclinical mental health problems are mixed. OBJECTIVE: To study self-reported mental health problems among adults born preterm at very low birth weight (VLBW; ≤1500 g) compared with term controls in an individual participant data meta-analysis. DATA SOURCES: Adults Born Preterm International Collaboration. STUDY SELECTION: Studies that compared self-reported mental health problems using the Achenbach Young Adult Self Report or Adult Self Report between adults born preterm at VLBW (n = 747) and at term (n = 1512)...
March 10, 2017: Pediatrics
https://www.readbyqxmd.com/read/28279702/molecular-characterization-of-classical-swine-fever-virus-isolates-from-india-during-2012-14
#4
Elina Khatoon, Nagendra N Barman, Manab Deka, Gitika Rajbongshi, Kongkon Baruah, Nipu Deka, Durlav P Bora, Sachin Kumar
Classical swine fever is a highly contagious and economically important viral disease of pigs. Outbreaks of classical swine fever virus (CSFV) were recorded in different places in the Kamrup district of Assam in India between the years 2012 and 2014. The nucleotide sequences of the 10 CSFV isolates were analyzed based on the partial nucleotide sequences of the E2, 5'NTR and NS5B genes. Phylogenetic analysis indicated the dominance of subgroup 2.2 along with 2.1 strains in the northeast part of India. Variation in the nucleotide sequences of E2, 5'NTR and 3'NS5B genes of CSFV allows tracking changes in the virus population over time...
March 6, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28276799/comparison-of-outcome-and-clinical-characteristics-of-bacteremia-caused-by-methicillin-resistant-penicillin-resistant-and-penicillin-susceptible-staphylococcus-aureus-strains
#5
Elina Jokinen, Janne Laine, Reetta Huttunen, Pekka Rahikka, Heini Huhtala, Risto Vuento, Jaana Vuopio, Jaana Syrjänen
BACKGROUND: The aim of this study was to assess the association of methicillin resistance and penicillinase production with clinical characteristics and outcome of Staphylococcus aureus bacteremia. METHODS: For 126 patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, 378 age- and gender-matched controls with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia were selected. Of controls, 126 had bacteremia caused by penicillin-susceptible strains (PSSA) and 252 by penicillinase-producing strains (PRSA)...
February 28, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28268826/seasonal-weight-variation-patterns-in-seven-countries-located-in-northern-and-southern-hemispheres
#6
Saeed Mehrang, Elina Helander, Angela Chieh, Ilkka Korhonen
The digital revolution of information and technology in late 20th century has led to emergence of devices that help people monitor their weight in a long-term manner. Investigation of population-level variations of body mass using smart connected weight scales enabled the health coaches acquire deeper insights about the models of people's behavior as a function of time. Typically, body mass varies when the seasons change. That is, during the warmer seasons people's body mass tend to decrease while in colder seasons it usually moves up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28264828/potential-determinants-of-vitamin-d-in-finnish-adults-a-cross-sectional-study-from-the-northern-finland-birth-cohort-1966
#7
Saranya Palaniswamy, Elina Hyppönen, Dylan M Williams, Jari Jokelainen, Estelle Lowry, Sirkka Keinänen-Kiukaanniemi, Karl-Heinz Herzig, Marjo-Riitta Järvelin, Sylvain Sebert
OBJECTIVE: Evidence from randomised controlled trials suggests that vitamin D may reduce multimorbidity, but very few studies have investigated specific determinants of vitamin D2 and D3 (two isoforms of 25-hydroxyvitamin D). The aim of the study was to investigate the determinants of vitamin D2 and D3 and to identify the risk factors associated with hypovitaminosis D. DESIGN: Cross-sectional study. SETTING: Northern Finland Birth Cohort 1966...
March 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28258980/in-situ-synthesis-of-exopolysaccharides-by-leuconostoc-spp-and-weissella-spp-and-their-rheological-impacts-in-fava-bean-flour
#8
Yan Xu, Yaqin Wang, Rossana Coda, Elina Säde, Päivi Tuomainen, Maija Tenkanen, Kati Katina
Fava bean flour is regarded as a potential plant-based protein source, but the addition of it at high concentration is restricted by its poor texture-improving ability and by anti-nutritional factors (ANF). Exopolysaccharides (EPS) produced by lactic acid bacteria (LAB) are regarded as good texture modifiers. In this study, fava bean flour was fermented with Leuconostoc spp. and Weissella spp. with or without sucrose addition, in order to evaluate their potential in EPS production. The contents of free sugars, organic acids, mannitol and EPS in all fermented fava bean doughs were measured...
February 21, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28250237/bovine-embryo-oviduct-interaction-in-vitro-reveals-an-early-crosstalk-mediated-by-bmp-signaling
#9
Elina Vanesa García, Meriem Hamdi, Antonio Daniel Barrera, Maria-Jesús Sánchez Calabuig, Alfonso Gutierrez-Adan, Dimitrios Rizos
Signaling components of Bone Morphogenetic Proteins (BMPs) are expressed in an anatomically and temporally regulated fashion in bovine oviduct. However, a local response of this signaling to the presence of the embryo has yet to be elucidated. The aim of the present study was to evaluate if early embryo-oviduct interaction induces changes in the gene expression of BMP signaling components. For this purpose, we used an in vitro co-culture system to investigate the local interaction between bovine oviductal epithelial cells (BOEC) from the isthmus region with early embryos during two developmental periods: before (from the 2-cell to 8-cell stage) or during (from the 8-cell to 16-cell stage) the main phase of embryonic genome activation (EGA)...
March 1, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28249569/unity-in-defence-honeybee-workers-exhibit-conserved-molecular-responses-to-diverse-pathogens
#10
Vincent Doublet, Yvonne Poeschl, Andreas Gogol-Döring, Cédric Alaux, Desiderato Annoscia, Christian Aurori, Seth M Barribeau, Oscar C Bedoya-Reina, Mark J F Brown, James C Bull, Michelle L Flenniken, David A Galbraith, Elke Genersch, Sebastian Gisder, Ivo Grosse, Holly L Holt, Dan Hultmark, H Michael G Lattorff, Yves Le Conte, Fabio Manfredini, Dino P McMahon, Robin F A Moritz, Francesco Nazzi, Elina L Niño, Katja Nowick, Ronald P van Rij, Robert J Paxton, Christina M Grozinger
BACKGROUND: Organisms typically face infection by diverse pathogens, and hosts are thought to have developed specific responses to each type of pathogen they encounter. The advent of transcriptomics now makes it possible to test this hypothesis and compare host gene expression responses to multiple pathogens at a genome-wide scale. Here, we performed a meta-analysis of multiple published and new transcriptomes using a newly developed bioinformatics approach that filters genes based on their expression profile across datasets...
March 2, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28248959/aspidoras-mephisto-new-species-the-first-troglobitic-callichthyidae-teleostei-siluriformes-from-south-america
#11
Luiz Fernando Caserta Tencatt, Maria Elina Bichuette
Aspidoras mephisto n. sp. is described from the Anésio-Russão cave system, upper Tocantins River basin, Goiás, Brazil. The species can be readily distinguished from its congeners by troglomorphic features and also by presenting the following combination of features: infraorbital 1 generally with well-developed ventral laminar; or moderately developed; poorly-developed serrations on posterior margin of pectoral spine; nuchal plate not externally visible; dorsal fin, even in conspicuously colored specimens, with only dark brown or black chromatophores concentrated on rays, forming spots in some specimens; membranes hyaline; or sparse dark brown or black chromatophores on membranes, not forming any conspicuous pattern; and inner laminar expansion of infraorbital 1 moderately developed...
2017: PloS One
https://www.readbyqxmd.com/read/28248716/intraepithelial-melanoma-in-the-stomach-after-treatment-with-immune-checkpoint-blockade-therapy
#12
Elina Shustef, Carlos A Torres-Cabala, Jonathan L Curry, Michael T Tetzlaff, Priyadharsini Nagarajan, Doina Ivan, Victor G Prieto, Phyu P Aung
Melanoma is the most common tumor to metastasize to the gastrointestinal tract, commonly affecting the small intestine, colon, and anorectum. Primary mucosal melanoma can arise in any gastrointestinal site, most frequently affecting anorectal mucosa. Melanoma involving the gastric mucosa, specifically, is exceedingly rare and carries a poor prognosis with a median survival of 5 months. The presence of atypical melanocytes exclusively within gastric epithelium has not been previously described. We report a case of a 52-year-old man with widespread BRAFV600E mutant metastatic melanoma who was referred to our institution for immune checkpoint antibody-blockade therapy...
February 23, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28245149/airborne-particulate-matter-induces-non-allergic-eosinophilic-sinonasal-inflammation-in-mice
#13
Murugappan Ramanathan, Nyall R London, Anuj Tharakan, Nitya Surya, Thomas E Sussan, Xiaoquan Rao, Sandra Y Lin, Elina Toskala, Sanjay Rajagopalan, Shyam Biswal
RATIONALE: Exposure to airborne particulate matter has been linked to aggravation of respiratory symptoms, increased risk of cardiovascular disease, and all-cause mortality. While the health effects of particulate matter on the lower pulmonary airway have been extensively studied, little is known regarding the impact of chronic particulate matter exposure on the upper sinonasal airway. OBJECTIVES: To test the impact of chronic airborne particulate matter exposure on the upper respiratory system in vivo...
February 28, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28240343/term-twin-birth-impact-of-mode-of-delivery-on-outcome
#14
Elina Ylilehto, Outi Palomäki, Heini Huhtala, Jukka Uotila
The main aims of this study were to compare maternal and neonatal outcomes in term twin birth according to the planned mode of delivery and to study the effects of chorionicity and inter-twin delivery time on neonatal outcome MATERIAL AND METHODS: A single-center cohort study of 495 women with twin deliveries at ≥ 37+0 weeks of gestation. Term twin deliveries were divided into a trial of labor group (TOL, 69.3%) and a planned cesarean section (CS) group (30.7%). The primary outcomes were maternal and neonatal morbidity RESULTS: 80...
February 27, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28236418/one-year-observational-study-of-palivizumab-prophylaxis-on-infants-at-risk-for-respiratory-syncytial-virus-infection-in-latin-america
#15
Leandro Martin Castillo, Gabriela Bugarin, Juan Carlos Arias, Jairo Israel Barajas Rangel, Maria Elina Serra, Nestor Vain
OBJECTIVE: This study aims to describe real world palivizumab use and effectiveness in high-risk Latin American infants and young children. METHOD: Prospective, multicenter observational study with infants at risk for severe RSV infection who received palivizumab according to routine clinical practice. Subjects were followed for one year with monthly visits after the first dose of palivizumab. An infant was considered adherent if receiving all the expected injections or five or fewer injections within appropriate inter-dose intervals...
February 22, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28235819/does-the-risk-of-hospitalisation-for-ischaemic-heart-disease-rise-already-before-widowhood
#16
Elina Einiö, Heta Moustgaard, Pekka Martikainen, Taina Leinonen
BACKGROUND: The death of a spouse has been shown to increase mortality from various causes, including ischaemic heart disease. It is unclear, however, whether cardiac problems are already on the rise before widowhood. METHODS: Using longitudinal register data of Finnish widows-to-be aged 65 and over at baseline (N=19 185), we assessed the risk of hospitalisation for ischaemic heart disease 18 months before and after widowhood. Hospital admissions were derived from national hospital discharge registers between 1996 and 2002...
February 24, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28235612/efficacy-and-safety-of-direct-acting-antiviral-regimens-in-hiv-hcv-coinfected-patients-french-anrs-co13-hepavih-cohort
#17
Lionel Piroth, Linda Wittkop, Karine Lacombe, Eric Rosenthal, Camille Gilbert, Patrick Miailhes, Patrizia Carrieri, Julie Chas, Isabelle Poizot-Martin, Anne Gervais, Stéphanie Dominguez, Didier Neau, David Zucman, Eric Billaud, Philippe Morlat, Hugues Aumaitre, Caroline Lascoux-Combe, Anne Simon, Olivier Bouchaud, Elina Teicher, Firouzé Bani-Sadr, Laurent Alric, Daniel Vittecoq, François Boué, Claudine Duvivier, Marc-Antoine Valantin, Laure Esterle, François Dabis, Philippe Sogni, Dominique Salmon
BACKGROUND & AIMS: Few data are available on the use of new oral direct-acting antiviral (DAA) regimens to treat HIV/HCV-coinfected patients in real-life settings. METHODS: HIV/HCV-coinfected patients enrolled in the ANRS CO13 HEPAVIH observational cohort were included if they began an all-oral DAA-based regimen before 1 May 2015 (12-week regimens) or 1 February 2015 (24-week regimens). Treatment success (SVR12) was defined by undetectable HCV-RNA 12 weeks after treatment cessation...
February 21, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28227022/seasonal-weight-variation-patterns-in-seven-countries-located-in-northern-and-southern-hemispheres
#18
Saeed Mehrang, Elina Helander, Angela Chieh, Ilkka Korhonen, Saeed Mehrang, Elina Helander, Angela Chieh, Ilkka Korhonen, Ilkka Korhonen, Saeed Mehrang, Elina Helander, Angela Chieh
The digital revolution of information and technology in late 20th century has led to emergence of devices that help people monitor their weight in a long-term manner. Investigation of population-level variations of body mass using smart connected weight scales enabled the health coaches acquire deeper insights about the models of people's behavior as a function of time. Typically, body mass varies when the seasons change. That is, during the warmer seasons people's body mass tend to decrease while in colder seasons it usually moves up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224618/the-feasibility-of-nbi-in-patients-with-suspected-upper-airway-lesions-a-multicenter-study
#19
Leif J J Bäck, Jami Rekola, Lassi Raittinen, Elina Halme, Petra Pietarinen, Harri Keski-Säntti, Leena-Maija Aaltonen, Antti A Mäkitie, Antti Raappana, Jukka Tikanto, Aleksi Schrey, Reidar Grenman, Jussi Laranne, Petri Koivunen, Heikki Irjala
OBJECTIVE: Narrow band imaging (NBI) improves diagnosis of laryngopharyngeal cancer, but most reported NBI studies are from experienced centers. Feasibility reports on use at everyday outpatient departments are needed. STUDY DESIGN: Researcher-initiated, prospective, multicenter. METHODS: Participating physicians were instructed in NBI technique during a 4-hour meeting. Patients underwent an examination that included endoscopy with white light (WL) high-definition (HD) TV and NBI filter in the selected time period...
February 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28223512/glucosylceramide-synthase-inhibition-alleviates-aberrations-in-synucleinopathy-models
#20
S Pablo Sardi, Catherine Viel, Jennifer Clarke, Christopher M Treleaven, Amy M Richards, Hyejung Park, Maureen A Olszewski, James C Dodge, John Marshall, Elina Makino, Bing Wang, Richard L Sidman, Seng H Cheng, Lamya S Shihabuddin
Mutations in the glucocerebrosidase gene (GBA) confer a heightened risk of developing Parkinson's disease (PD) and other synucleinopathies, resulting in a lower age of onset and exacerbating disease progression. However, the precise mechanisms by which mutations in GBA increase PD risk and accelerate its progression remain unclear. Here, we investigated the merits of glucosylceramide synthase (GCS) inhibition as a potential treatment for synucleinopathies. Two murine models of synucleinopathy (a Gaucher-related synucleinopathy model, Gba(D409V/D409V) and a A53T-α-synuclein overexpressing model harboring wild-type alleles of GBA, A53T-SNCA mouse model) were exposed to a brain-penetrant GCS inhibitor, GZ667161...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
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