keyword
MENU ▼
Read by QxMD icon Read
search

Elina

keyword
https://www.readbyqxmd.com/read/29335920/clergy-s-beliefs-about-mental-illness-and-their-perception-of-its-treatability-experience-from-a-church-based-prevention-of-mother-to-child-hiv-transmission-pmtct-trial-in-nigeria
#1
Theddeus Iheanacho, Elina Stefanovics, Echezona E Ezeanolue
Clergy participating in the Healthy Beginning Initiative (N = 45), a program utilizing church workers to integrate packages of care into church activities, completed a 43-item self-administered questionnaire assessing their attitudes and beliefs about mental disorders and perception of their treatability. A majority believed that drug/alcohol use, stress and genetic inheritance could cause mental illness and that society needed to adopt more tolerant attitude toward people with mental disorders. Clergy with contact with people with mental disorders were more likely to perceive depression as treatable...
January 15, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29335026/congenital-anomalies-in-neurofibromatosis-1-a-retrospective-register-based-total-population-study
#2
Jussi Leppävirta, Roope A Kallionpää, Elina Uusitalo, Tero Vahlberg, Minna Pöyhönen, Juha Peltonen, Sirkku Peltonen
BACKGROUND: Neurofibromatosis type 1 (NF1) is a dominantly inherited Rasopathy caused by mutations in the NF1 gene on chromosome 17. NF1 has been connected to congenital anomalies, e.g., in the skeletal and cardiovascular systems, but the overall incidence of anomalies is unknown. In this retrospective register-based total population study conducted in Finland, the congenital anomalies in NF1 were evaluated. METHODS: One thousand four hundred ten patients with NF1 were identified by searching the medical records related to inpatient and outpatient hospital visits of patients with an associated diagnosis for NF1 in 1987-2011...
January 15, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29334462/pot-economy-autooxidative-condensation-of-2-aryl-2-lithio-1-3-dithianes
#3
João R Vale, Tatu Rimpiläinen, Elina Sievanen, Kari Rissanen, Carlos A M Afonso, Nuno R Candeias
The autooxidative condensation of 2-aryl-2-lithio-1,3-dithianes is here reported. Treatment of 2-aryl-1,3-dithianes with n-BuLi in the absence of any electrophile leads to condensation of three molecules of 1,3-dithianes and formation of highly functionalized α-thioether ketones orthothioesters in 51-89% yields upon air exposure. The method was further expanded to benzaldehyde dithioacetals, affording corresponding orthothioesters and α-thioether ketones in 48-97% yields. The experimental results combined with density functional theory studies support a mechanism triggered by the autooxidation of 2-aryl-2-lithio-1,3-dithianes to yield a highly reactive thioester that undergoes condensation with two other molecules of 2-aryl-2-lithio-1,3-dithiane...
January 15, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29334432/antibiotic-use-patterns-in-endoscopic-sinus-surgery-a-survey-of-the-american-rhinologic-society-membership
#4
Christina H Fang, Judd H Fastenberg, Marvin P Fried, Elina Jerschow, Nadeem A Akbar, Waleed M Abuzeid
BACKGROUND: There is a paucity of data supporting antibiotic use in endoscopic sinus surgery (ESS). The objective of this study is to determine perioperative antibiotic use patterns and factors which influence use in ESS. METHODS: An online-based survey was distributed to members of the American Rhinologic Society (ARS). Outcomes included timing of perioperative antibiotic use, practice environment, years of experience, and patient factors that influenced antibiotic use...
January 15, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29332234/attitudes-of-u-s-psychiatry-residents-and-fellows-towards-mental-illness-and-its-causes-a-comparison-study-with-medical-students
#5
Catherine Chiles, Elina Stefanovics, Robert Rosenheck
Stigma towards people with mental illness remains a burden for patients and healthcare providers. This study at a large US university examined the attitudes of psychiatry residents and fellows towards mental illness and its causes, and whether their attitudes differed from the medical student attitudes previously studied utilizing the same survey method. An electronic questionnaire examining attitudes toward people with mental illness, causes of mental Illness, and treatment efficacy was used to survey the attitudes of psychiatry residents and fellows...
January 13, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29326266/the-epigenetic-control-of-stemness-in-cd8-t-cell-fate-commitment
#6
Luigia Pace, Christel Goudot, Elina Zueva, Paul Gueguen, Nina Burgdorf, Joshua J Waterfall, Jean-Pierre Quivy, Geneviève Almouzni, Sebastian Amigorena
After priming, naïve CD8+ T lymphocytes establish specific heritable transcription programs that define progression to long-lasting memory cells or to short-lived effector cells. Although lineage specification is critical for protection, it remains unclear how chromatin dynamics contributes to the control of gene expression programs. We explored the role of gene silencing by the histone methyltransferase Suv39h1. In murine CD8+ T cells activated after Listeria monocytogenes infection, Suv39h1-dependent trimethylation of histone H3 lysine 9 controls the expression of a set of stem cell-related memory genes...
January 12, 2018: Science
https://www.readbyqxmd.com/read/29318646/improving-the-validity-of-script-concordance-testing-by-optimising-and-balancing-items
#7
Michael Sh Wan, Elina Tor, Judith Nicky Hudson
BACKGROUND: A script concordance test (SCT) is a modality for assessing clinical reasoning. Concerns had been raised about the plausible validity threat to SCT scores if students deliberately avoided the extreme answer options to obtain higher scores. The aims of the study were firstly to investigate whether students' avoidance of the extreme answer options could result in higher scores, and secondly to determine whether a 'balanced approach' by careful construction of SCT items (to include extreme as well as median options as model responses) would improve the validity of an SCT...
January 9, 2018: Medical Education
https://www.readbyqxmd.com/read/29315614/defining-the-phenotypic-spectrum-of-slc6a1-mutations
#8
Katrine M Johannesen, Elena Gardella, Tarja Linnankivi, Carolina Courage, Anne de Saint Martin, Anna-Elina Lehesjoki, Cyril Mignot, Alexandra Afenjar, Gaetan Lesca, Marie-Thérèse Abi-Warde, Jamel Chelly, Amélie Piton, J Lawrence Merritt, Lance H Rodan, Wen-Hann Tan, Lynne M Bird, Mark Nespeca, Joseph G Gleeson, Yongjin Yoo, Murim Choi, Jong-Hee Chae, Desiree Czapansky-Beilman, Sara Chadwick Reichert, Manuela Pendziwiat, Judith S Verhoeven, Helenius J Schelhaas, Orrin Devinsky, Jakob Christensen, Nicola Specchio, Marina Trivisano, Yvonne G Weber, Caroline Nava, Boris Keren, Diane Doummar, Elise Schaefer, Sarah Hopkins, Holly Dubbs, Jessica E Shaw, Laura Pisani, Candace T Myers, Sha Tang, Shan Tang, Deb K Pal, John J Millichap, Gemma L Carvill, Kathrine L Helbig, Oriano Mecarelli, Pasquale Striano, Ingo Helbig, Guido Rubboli, Heather C Mefford, Rikke S Møller
OBJECTIVE: Pathogenic SLC6A1 variants were recently described in patients with myoclonic atonic epilepsy (MAE) and intellectual disability (ID). We set out to define the phenotypic spectrum in a larger cohort of SCL6A1-mutated patients. METHODS: We collected 24 SLC6A1 probands and 6 affected family members. Four previously published cases were included for further electroclinical description. In total, we reviewed the electroclinical data of 34 subjects. RESULTS: Cognitive development was impaired in 33/34 (97%) subjects; 28/34 had mild to moderate ID, with language impairment being the most common feature...
January 8, 2018: Epilepsia
https://www.readbyqxmd.com/read/29315179/prevalence-of-hearing-loss-and-hearing-care-use-among-asian-americans-a-nationally-representative-sample
#9
Janet S Choi, Elina Kari, Rick A Friedman, Laurel M Fisher
OBJECTIVE: To assess the prevalence of hearing loss and factors affecting hearing care use among Asian Americans, using the first nationally representative sample of Asian Americans. STUDY DESIGN: National cross-sectional survey. SETTING: Ambulatory examination centers. PATIENTS: Three thousand six hundred twelve adults (522 Asian American) aged 20 to 69 in the 2011 to 2012 National Health and Examination Survey with pure-tone audiometry...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29314514/non-immediate-heparin-and-heparinoid-cutaneous-allergic-reactions-a-role-for-fondaparinux
#10
Elina Tan, Grace Thompson, Charlotta Ekstrom, Michaela Lucas
Non-immediate allergic cutaneous reactions to heparins have been increasingly reported, typically manifesting as large, eczematous plaques at sites of subcutaneous injection. Patients may demonstrate cross-reactivity between unfractionated heparin, low molecular weight heparin and semi-synthetic heparinoids, making finding an alternative difficult. Fondaparinux has been identified as a useful alternative in such patients; here we present the first two documented cases in Australia and a literature review.
January 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29302317/causes-of-death-among-women-aged-17-49-years-between-2007-and-2010-in-maputo-mozambique
#11
Saara Parkkali, Bright I Nwaru, Orvalho Augusto, Fatima Abacassamo, Julie Cliff, Elina Hemminki
Objectives: To describe causes of death among young women and estimate the role of HIV/AIDS as a cause in Maputo City, based on the civil death register. Methods: Death data of 17-49 year-old women were abstracted from January 2007-March 2010 from the civil death register in Maputo City, registering overall about 15 000 deaths per-year. Causes of death in the register were either based on physicians' diagnoses on death certificates or determined by asking questions to deceased relatives...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29300333/atomic-resolution-structures-of-human-bufaviruses-determined-by-cryo-electron-microscopy
#12
Maria Ilyas, Mario Mietzsch, Shweta Kailasan, Elina Väisänen, Mengxiao Luo, Paul Chipman, J Kennon Smith, Justin Kurian, Duncan Sousa, Robert McKenna, Maria Söderlund-Venermo, Mavis Agbandje-McKenna
Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, including Finland, the Netherlands, and Bhutan, in pediatric patients exhibiting similar symptoms. Towards their characterization, the structures of virus-like particles of BuV1, BuV2, and BuV3, the current known genotypes, have been determined by cryo-electron microscopy and image reconstruction to 2...
January 4, 2018: Viruses
https://www.readbyqxmd.com/read/29298539/cholesteatoma-surgery-with-the-canal-wall-up-technique-combined-with-mastoid-obliteration-results-from-primary-surgery-in-230-consecutive-cases
#13
Johanna Westerberg, Elina Mäki-Torkko, Henrik Harder
OBJECTIVE: To evaluate the canal wall up (CWU) technique combined with mastoid obliteration used in cholesteatoma surgery from the aspects of safety and function. STUDY DESIGN: Retrospective chart review. Information was extracted from a medical database and complementary data from patient files and audiograms were collected and recorded retrospectively. SETTING: A tertiary-stage hospital and a secondary-stage hospital. Surgeons of various levels of experience...
January 3, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29298037/mthpc-conjugated-gold-nanoparticles-as-a-tool-to-improve-photodynamic-therapy
#14
Elina Haimov, Hana Weitman, Shlomi Polani, Hadas Schori, David Zitoun, Orit Shefi
Photodynamic Therapy (PDT) is a promising therapeutic modality for cancer. However, current protocols using bare drugs suffer from several limitations that impede its beneficial clinical effects. Here, we introduce a new approach for an efficient PDT treatment. It involves conjugating a PDT agent, meso-tetrahydroxy-phenylchlorin (mTHPC) photosensitizer, to gold nanoparticles (AuNPs) that serve as carriers for the drug. AuNPs have a number of characteristics that make them highly suitable to function as drug carriers: they are biocompatible, serve as biomarkers and function as contrast agents in vitro and in vivo...
January 3, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29296508/two-photon-microscopy-imaging-of-oxidative-stress-in-human-living-erythrocytes
#15
Gohar Tsakanova, Elina Arakelova, Violetta Ayvazyan, Anna Ayvazyan, Stepan Tatikyan, Rouben Aroutiounian, Yeva Dalyan, Samvel Haroutiunian, Vasili Tsakanov, Arsen Arakelyan
Red blood cells (RBCs) are known to be the most suitable cells to study oxidative stress, which is implicated in the etiopathology of many human diseases. The goal of the current study was to develop a new effective approach for assessing oxidative stress in human living RBCs using two-photon microscopy. To mimic oxidative stress in human living RBCs, an in vitro model was generated followed by two-photon microscopy imaging. The results revealed that oxidative stress is clearly visible on the two-photon microscopy images of RBCs under oxidative stress compared to no fluorescence in controls (P<0...
December 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/29285267/a-molecular-signature-of-lung-cancer-potential-biomarkers-for-adenocarcinoma-and-squamous-cell-carcinoma
#16
Varda Shoshan-Barmatz, Yael Bishitz, Avijit Paul, Yakov Krelin, Itay Nakdimon, Nir Peled, Avia Lavon, Elina Rudoy-Zilberman, Yael Refaely
Adenocarcinoma (AC) and squamous cell carcinoma (SCC), sub-types of non-small cell lung cancer (NSCLC), both present unique features at the genome, epigenome, transcriptome and proteome levels, as well as shared clinical and histopathological characteristics, but differ in terms of treatment. To ensure proper treatment, one must be able to distinguish between these sub-types. Here, we identify novel biomarker proteins in NSCLC, allowing for distinguishing between the AC and SCC sub-types. Proteomics analysis distinguished between healthy and tumor tissues, with the expression level of 1,494 proteins being altered, 378 of which showed a ≥|100|-fold change...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29278384/marine-cryptophytes-are-great-sources-of-epa-and-dha
#17
Elina Peltomaa, Matthew D Johnson, Sami J Taipale
Microalgae have the ability to synthetize many compounds, some of which have been recognized as a source of functional ingredients for nutraceuticals with positive health effects. One well-known example is the long-chain polyunsaturated fatty acids (PUFAs), which are essential for human nutrition. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are the two most important long-chain omega-3 (ω-3) PUFAs involved in human physiology, and both industries are almost exclusively based on microalgae. In addition, algae produce phytosterols that reduce serum cholesterol...
December 26, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29276046/drug-target-commons-a-community-effort-to-build-a-consensus-knowledge-base-for-drug-target-interactions
#18
Jing Tang, Zia-Ur-Rehman Tanoli, Balaguru Ravikumar, Zaid Alam, Anni Rebane, Markus Vähä-Koskela, Gopal Peddinti, Arjan J van Adrichem, Janica Wakkinen, Alok Jaiswal, Ella Karjalainen, Prson Gautam, Liye He, Elina Parri, Suleiman Khan, Abhishekh Gupta, Mehreen Ali, Laxman Yetukuri, Anna-Lena Gustavsson, Brinton Seashore-Ludlow, Anne Hersey, Andrew R Leach, John P Overington, Gretchen Repasky, Krister Wennerberg, Tero Aittokallio
Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights into therapeutic potential and possible adverse effects. The existing compound-target bioactivity data resources are often incomparable due to non-standardized and heterogeneous assay types and variability in endpoint measurements. To extract higher value from the existing and future compound target-profiling data, we implemented an open-data web platform, named Drug Target Commons (DTC), which features tools for crowd-sourced compound-target bioactivity data annotation, standardization, curation, and intra-resource integration...
December 15, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/29261808/correction-perinatal-outcomes-after-induced-termination-of-pregnancy-by-methods-a-nationwide-register-based-study-of-first-births-in-finland-1996-2013
#19
Situ Kc, Elina Hemminki, Mika Gissler, Suvi M Virtanen, Reija Klemetti
[This corrects the article DOI: 10.1371/journal.pone.0184078.].
2017: PloS One
https://www.readbyqxmd.com/read/29248729/a-novel-3d-heterotypic-spheroid-model-for-studying-extracellular-vesicle-mediated-tumour-and-immune-cell-communication
#20
Lilite Sadovska, Elīna Zandberga, Krizia Sagini, Kaspars Jēkabsons, Una Riekstiņa, Zane Kalniņa, Alicia Llorente, Aija Linē
Cancer-derived extracellular vesicles (EVs) have emerged as important mediators of tumour-host interactions, and they have been shown to exert various functional effects in immune cells. In most of the studies on human immune cells, EVs have been isolated from cancer cell culture medium or patients' body fluids and added to the immune cell cultures. In such a setting, the physiological relevance of the chosen EV concentration is unknown and the EV isolation method and the timing of EV administration may bias the results...
December 14, 2017: Biochemical and Biophysical Research Communications
keyword
keyword
91147
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"