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https://www.readbyqxmd.com/read/28916596/cutaneous-angiosarcoma-a-current-update
#1
REVIEW
Elina Shustef, Viktoryia Kazlouskaya, Victor G Prieto, Doina Ivan, Phyu P Aung
Cutaneous angiosarcoma (cAS) is a rare malignant neoplasm with variable clinical presentation. Although a distinct vascular tumour, cAS shares many overlapping histopathological features with other vasoformative and epithelioid tumours or 'mimickers'. cAS shows aggressive behaviour and carries a grave prognosis, thus early diagnosis is of paramount importance to achieve the best possible outcomes. Recently, several genetic studies were conducted leading to the identification of novel molecular targets in the treatment of cAS...
September 15, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28914106/concomitant-diseases-and-their-effect-on-disease-prognosis-in-meniere-s-disease-diabetes-mellitus-identified-as-a-negative-prognostic-factor
#2
Teemu Pieskä, Jouko Kotimäki, Minna Männikkö, Martti Sorri, Elina Hietikko
OBJECTIVE: To study comorbidities and their effect on the disease progression in Meniere's disease (MD). METHODS: Retrospective study on 350 definite MD patients diagnosed according to AAO-HNS 1995 criteria using hospital records and postal questionnaire. RESULTS: The prevalence of migraine, hypothyroidism, allergies, coronary heart disease and autoimmune diseases was more common in MD patients than reported in the general population of Finland...
September 15, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28912961/trpa1-expression-is-downregulated-by-dexamethasone-and-aurothiomalate-in-human-chondrocytes-trpa1-as-a-novel-factor-and-drug-target-in-arthritis
#3
Elina Nummenmaa, Mari Hämäläinen, Lauri J Moilanen, Teemu Moilanen, Katriina Vuolteenaho, Eeva Moilanen
No abstract text is available yet for this article.
2017: RMD Open
https://www.readbyqxmd.com/read/28911251/patient-enablement-after-a-single-appointment-with-a-gp-analysis-of-finnish-qualicopc-data
#4
Elina Tolvanen, Tuomas H Koskela, Mika Helminen, Elise Kosunen
BACKGROUND: Patient enablement is described as patient's ability to understand and cope with illness after a consultation. The purpose of this study was to analyze factors associated with enablement in Finnish primary health care. An additional aim was to evaluate whether a single question could be used to measure enablement. METHODS: A questionnaire survey was addressed to Finnish general practitioners (GPs) within the Quality and Costs of Primary Care in Europe (QUALICOPC) study framework...
September 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28899016/reply-the-phenotypic-and-molecular-spectrum-of-peho-syndrome-and-peho-like-disorders
#5
Anna-Kaisa Anttonen, Anna-Elina Lehesjoki
No abstract text is available yet for this article.
August 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28892118/association-of-trial-registration-with-reporting-of-primary-outcomes-in-protocols-and-publications
#6
An-Wen Chan, Annukka Pello, Jessica Kitchen, Anna Axentiev, Jorma I Virtanen, Annie Liu, Elina Hemminki
No abstract text is available yet for this article.
September 11, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28889479/associations-of-oral-fluid-mmp-8-with-periodontitis-in-swiss-adult-subjects
#7
Matti Mauramo, Adrian M Ramseier, Elina Mauramo, Andreas Buser, Taina Tervahartiala, Timo Sorsa, Tuomas Waltimo
OBJECTIVE: MMP-8 is a prominent collagenase in periodontal disease. This cross-sectional study examined whether MMP-8 levels in saliva and gingival crevicular fluid (GCF) are associated with periodontitis in a Swiss population. SUBJECTS AND METHODS: 258 subjects (107 m, 151 f, mean age: 43.5 yr; range: 21-58 yr) acquired from the Swiss bone marrow donor registry participated in the study. Saliva and GCF samples were collected from subjects followed by a thorough dental and periodontal examination...
September 10, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28888631/incidence-of-elephant-endotheliotropic-herpesvirus-in-asian-elephants-in-india
#8
Nagendra N Barman, Bhaskar Choudhury, Vishnu Kumar, Monika Koul, Sophia M Gogoi, Elina Khatoon, A Chakroborty, P Basumatary, B Barua, T Rahman, S K Das, Sachin Kumar
Elephant endotheliotropic herpesviruses (EEHVs) are the cause of acute hemorrhagic disease in endangered Asian and African elephants. In the present study, we report the incidence of EEHV infection and associated mortality in the captive elephant of Assam, India. Our result showed the gross morphology and histopathological changes of EEHV infection in the elephant. Moreover, the phylogenetic analysis of the polymerase, helicase, and GPCR genes from the infected tissue samples suggested the presence of EEHV1A virus...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28888247/fatal-anaphylaxis-mortality-rate-and-risk-factors
#9
Paul J Turner, Elina Jerschow, Thisanayagam Umasunthar, Robert Lin, Dianne E Campbell, Robert J Boyle
Up to 5% of the US population has suffered anaphylaxis. Fatal outcome is rare, such that even for people with known venom or food allergy, fatal anaphylaxis constitutes less than 1% of total mortality risk. The incidence of fatal anaphylaxis has not increased in line with hospital admissions for anaphylaxis. Fatal drug anaphylaxis may be increasing, but rates of fatal anaphylaxis to venom and food are stable. Risk factors for fatal anaphylaxis vary according to cause. For fatal drug anaphylaxis, previous cardiovascular morbidity and older age are risk factors, with beta-lactam antibiotics, general anesthetic agents, and radiocontrast injections the commonest triggers...
September 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28887501/voluntary-liquorice-ingestion-increases-blood-pressure-via-increased-volume-load-elevated-peripheral-arterial-resistance-and-decreased-aortic-compliance
#10
Elina J Hautaniemi, Anna M Tahvanainen, Jenni K Koskela, Antti J Tikkakoski, Mika Kähönen, Marko Uitto, Kalle Sipilä, Onni Niemelä, Jukka Mustonen, Ilkka H Pörsti
We investigated the haemodynamic effects of two-week liquorice exposure (glycyrrhizin dose 290-370 mg/day) in 22 healthy volunteers during orthostatic challenge. Haemodynamics were recorded during passive 10-minute head-up tilt using radial pulse wave analysis, whole-body impedance cardiography, and spectral analysis of heart rate variability. Thirty age-matched healthy subjects served as controls. Liquorice ingestion elevated radial systolic (p < 0.001) and diastolic (p = 0.018) blood pressure and systemic vascular resistance (p = 0...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28887260/the-use-of-smart-phone-thermal-imaging-for-assessment-of-peripheral-perfusion-in-vascular-patients
#11
Gabriel A Wallace, Niten Singh, Elina Quiroga, Nam T Tran
BACKGROUND: Ankle brachial index (ABI) is a reliable method to evaluate extremity perfusion but can be prohibitive to obtain secondary to patient discomfort or extremity trauma. This study investigates smart phone based forward looking infrared imaging (FLIR) to assess peripheral perfusion using thermal ABI (tABI). METHODS: ABI's were measured by a certified vascular laboratory. Thermographs of each extremity (hands/feet) were obtained and maximum surface temperature recorded...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28884143/use-of-genotype-mtbdrplus-assay-for-diagnosis-of-multidrug-resistant-tuberculosis-in-nepal
#12
Elina Maharjan, Narayan Dutt Pant, Sanjeev Neupane, Jyoti Amatya, Bhawana Shrestha
The main aims of this study were to study the patterns of mutations in rpoB, katG, and inhA genes in Mycobacterium tuberculosis strains isolated from patients from Nepal and to evaluate the performance of genotype MTBDRplus assay, taking conventional drug susceptibility testing as gold standard for diagnosis of MDR-TB. A total of 69 Mycobacterium tuberculosis strains isolated from 73 smear positive sputum samples from patients suspected of suffering from multidrug-resistant tuberculosis were used in our study...
2017: International Scholarly Research Notices
https://www.readbyqxmd.com/read/28878546/a-case-of-rapidly-destructive-osteoarthritis-of-the-hip-with-onset-of-less-than-six-weeks
#13
Elina Huerfano, Maria Bautista, Guillermo Bonilla, Mauricio Palau-Lazaro, Adolfo Llinás, Daniel Monsalvo
INTRODUCTION: Rapidly destructive osteoarthritis is characterized by a severe destruction of the hip joint developing over short periods of time. However, to date, there is no agreement on the biological process that triggers this condition. The aim of this report is to present a case of rapidly destructive osteoarthritis. CASE REPORT: We report a case of a 76 year-old female who presented with hip pain of sudden onset and normal X-rays. Six weeks later she presented with increased pain intensity, functional limitation and evidence of a collapse of the femoral head in the X-rays...
August 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28877733/insecticide-use-pattern-and-phenotypic-susceptibility-of-anopheles-gambiae-sensu-lato-to-commonly-used-insecticides-in-lower-moshi-northern-tanzania
#14
Elinas J Nnko, Charles Kihamia, Filemoni Tenu, Zul Premji, Eliningaya J Kweka
BACKGROUND: Evidence of insecticide resistance has been documented in different malaria endemic areas. Surveillance studies to allow prompt investigation of associated factors to enable effective insecticide resistance management are needed. The objective of this study was to assess insecticide use pattern and phenotypic susceptibility level of Anopheles gambiae sensu lato to insecticides commonly used in malaria control in Moshi, northern Tanzania. METHODS: A cross-sectional survey was conducted to assess insecticide usage pattern...
September 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28877482/high-yield-methods-for-accurate-two-alternative-visual-psychophysics-in-head-fixed-mice
#15
Christopher P Burgess, Armin Lak, Nicholas A Steinmetz, Peter Zatka-Haas, Charu Bai Reddy, Elina A K Jacobs, Jennifer F Linden, Joseph J Paton, Adam Ranson, Sylvia Schröder, Sofia Soares, Miles J Wells, Lauren E Wool, Kenneth D Harris, Matteo Carandini
Research in neuroscience increasingly relies on the mouse, a mammalian species that affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield methods for probing mouse visual decisions. Mice are head-fixed, facilitating repeatable visual stimulation, eye tracking, and brain access. They turn a steering wheel to make two alternative choices, forced or unforced. Learning is rapid thanks to intuitive coupling of stimuli to wheel position. The mouse decisions deliver high-quality psychometric curves for detection and discrimination and conform to the predictions of a simple probabilistic observer model...
September 5, 2017: Cell Reports
https://www.readbyqxmd.com/read/28876384/influence-of-substrate-on-the-richness-and-composition-of-neotropical-cave-fauna
#16
Tamires Zepon, Maria Elina Bichuette
The food base in the subterranean environment consists mainly of allochthonous materials. In this environment the resources are distributed generally in a heterogeneous dispersed way and the distribution of resources and their availability determine where the terrestrial invertebrates will reside, which is important for understanding ecological relationships and to establish conservation strategies. Thus, we tested how the complexity of substrates influences the richness and composition of the subterranean terrestrial invertebrates in the Presidente Olegário karst area, southeastern Brazil...
August 31, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28874657/emergence-of-native-peptide-sequences-in-prebiotic-replication-networks
#17
Jayanta Nanda, Boris Rubinov, Denis Ivnitski, Rakesh Mukherjee, Elina Shtelman, Yair Motro, Yifat Miller, Nathaniel Wagner, Rivka Cohen-Luria, Gonen Ashkenasy
Biopolymer syntheses in living cells are perfected by an elaborate error correction machinery, which was not applicable during polymerization on early Earth. Scientists are consequently striving to identify mechanisms by which functional polymers were selected and further amplified from complex prebiotic mixtures. Here we show the instrumental role of non-enzymatic replication in the enrichment of certain product(s). To this end, we analyzed a complex web of reactions in β-sheet peptide networks, focusing on the formation of specific intermediate compounds and template-assisted replication...
September 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/28871154/herbivores-rescue-diversity-in-warming-tundra-by-modulating-trait-dependent-species-losses-and-gains
#18
Elina Kaarlejärvi, Anu Eskelinen, Johan Olofsson
Climate warming is altering the diversity of plant communities but it remains unknown which species will be lost or gained under warming, especially considering interactions with other factors such as herbivory and nutrient availability. Here, we experimentally test effects of warming, mammalian herbivory and fertilization on tundra species richness and investigate how plant functional traits affect losses and gains. We show that herbivory reverses the impact of warming on diversity: in the presence of herbivores warming increases species richness through higher species gains and lower losses, while in the absence of herbivores warming causes higher species losses and thus decreases species richness...
September 4, 2017: Nature Communications
https://www.readbyqxmd.com/read/28869872/semi-preparative-high-performance-countercurrent-chromatography-method-for-the-purification-of-chemically-synthesized-atp-analogue-apppi
#19
Elina Puljula, Petri A Turhanen
An efficient high-performance countercurrent chromatography (HPCCC) based method has been developed for the purification of chemically synthesized 1-adenosin-5'-yl 3-(3-methylbut-3-enyl)triphosphoric acid diester (ApppI). ApppI is an adenosine triphosphate (ATP) analogue with biological significance due to its varied actions in the body. ApppI was synthesized and purified as its tetrabutylammonium (TBA) salt and converted successfully into its more practical sodium salt form after purification. The amount of TBA hydroxide (2...
August 30, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28866307/evaluation-of-periprocedural-hypersensitivity-reactions
#20
Melissa Iammatteo, Taha Keskin, Elina Jerschow
BACKGROUND: Identifying the cause of periprocedural hypersensitivity reactions (HSRs) remains challenging because of the multitude of medications involved. Antibiotics are the most common cause in the United States, whereas neuromuscular blocking agents are most common in Europe. OBJECTIVE: To identify causative agents for periprocedural HSRs. METHODS: This study was a 7-year retrospective medical record review of patients evaluated between December 2009 and January 2017 at a drug allergy center in Bronx, New York for periprocedural HSRs, defined as occurring soon before, during, or soon after a medical procedure or operation with or without general anesthesia...
August 30, 2017: Annals of Allergy, Asthma & Immunology
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