keyword
https://read.qxmd.com/read/38536661/trial-of-labor-after-2-previous-cesareans-a-multicenter-study
#1
JOURNAL ARTICLE
Yael Gold Zamir, Tzuria Peled, Hila Hochler, Hen Y Sela, Ari Weiss, Michal Lipschuetz, Joshua Isaac Rosenbloom, Sorina Grisaru-Granovsky, Misgav Rottenstreich
BACKGROUND: Trial of labor after cesarean after 2 cesarean deliveries is linked to a lower success rate of vaginal delivery and higher rates of adverse obstetrical outcomes than trial of labor after cesarean after 1 previous cesarean delivery. OBJECTIVE: This study aimed to investigate the factors associated with failed trial of labor after cesarean among women with 2 previous cesarean deliveries. STUDY DESIGN: This was a multicenter retrospective cohort study, which included all women with singleton pregnancies attempting trial of labor after cesarean after 2 previous cesarean deliveries between 2003 and 2021...
December 1, 2023: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38532503/the-repair-study-oral-antibiotics-to-prevent-infection-and-wound-dehiscence-after-obstetric-perineal-tear-a-double-blinded-placebo-controlled-randomized-trial
#2
JOURNAL ARTICLE
Kathrine Perslev, Niels Klarskov, Thomas Bergholt, Hanna Jangö
BACKGROUND: Approximately 85% of women experience an obstetric tear at delivery and up to 25% subsequently experience wound dehiscence and/or infection. Previous publications suggest that intravenous antibiotics administrated during delivery reduces this risk. We do not know if oral antibiotics given after delivery can reduce the risk of wound dehiscence or infection. Our aim is to investigate whether three doses of oral antibiotics (amoxicillin 500 mg/clavulanic acid 125 mg) given after delivery can reduce the risk of wound dehiscence and infection in patients with a second-degree obstetric tear or episiotomy...
March 27, 2024: Trials
https://read.qxmd.com/read/38532280/procalcitonin-and-c-reactive-protein-as-early-markers-of-anastomotic-leakage-in-intestinal-resections-for-advanced-ovarian-cancer-edmocs
#3
JOURNAL ARTICLE
José Luis Sánchez-Iglesias, Clara Morales-Coma, Lucas Minig, Víctor Lago, Santiago Domingo, Gemma Mancebo, Jaime Siegrist, María Soledad Fidalgo García, Antoni Llueca, Anna Serra, Paloma Cobas Lozano, Arantza Lekuona Artola, Natalia R Gómez-Hidalgo, Úrsula Acosta, Roser Ferrer-Costa, Melissa Bradbury, Assumpció Pérez-Benavente, Antonio Gil-Moreno
INTRODUCTION: Serum levels of procalcitonin and C-reactive protein (CRP) have been used to predict anastomotic leakage after colorectal surgery, but information is scarce in advanced ovarian cancer (AOC) surgery with bowel resection. This study aimed to assess the predictive value of procalcitonin and CRP in detecting anastomotic leakage after AOC surgery with bowel resection. The study also aimed to determine the optimal postoperative reference values and the best day for evaluating these markers...
March 26, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38531628/a-rapid-improvement-event-progesterone-prescribing-in-prevention-of-miscarriage
#4
JOURNAL ARTICLE
Lucy Anne Bolger, Nicola O'Riordan, Cathy Allen
A rapid improvement event (RIE) is a standard operational excellence technique that uses team-based problem solving to improve processes. In this study, a RIE was undertaken to improve progesterone prescribing rates for those with a history of miscarriage experiencing vaginal bleeding in early pregnancy. This was on the basis of a recent change in guidelines regarding prescribing in these instances. NICE guidelines changed in November 2021 after Cochrane meta-analysis and the PRISM (Progesterone in Spontaneous Miscarriage) randomised control trial demonstrated a higher incidence of live births in those prescribed vaginal micronised progesterone for threatened miscarriage, when compared with those not prescribed it...
March 26, 2024: BMJ Open Quality
https://read.qxmd.com/read/38531377/a-crossover-trial-evaluating-coconut-oil-as-an-alternative-to-commercial-ultrasound-gel-in-obstetrical-ultrasounds
#5
JOURNAL ARTICLE
Claire Edelman, Caroline Rouse, Ziyi Yang, Myanna Cook, Joanne Daggy, Anthony Shanks
OBJECTIVE:  Our objective was to evaluate the quality of obstetrical ultrasound images obtained with coconut oil compared with commercial ultrasound gel and to assess patient acceptability. STUDY DESIGN:  This was a randomized two-period crossover study in which 40 pregnant patients had standard biometry images obtained with both coconut oil and commercial ultrasound gel during their growth or anatomy ultrasound. All images were then rated by two blinded maternal-fetal medicine physicians on quality, resolution, and detail using a 0 to 100 scale...
March 26, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38530442/editorial-expression-of-concern-the-effect-of-alpha-lipoic-acid-on-uterine-wound-healing-after-primary-cesarean-section-a-triple-blind-placebo-controlled-parallel-group-randomized-clinical-trial
#6
Hazem Sammour, Abdellatif Elkholy, Radwa Rasheedy, Ebtesam Fadel
No abstract text is available yet for this article.
March 26, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38530330/comparison-of-spontaneous-pushing-and-directed-pushing-during-the-second-stage-of-labor-among-chinese-women-without-epidural-analgesia-protocol-for-a-noninferior-feasibility-study
#7
JOURNAL ARTICLE
Jiasi Yao, Heike Roth, Debra Anderson, Hong Lu, Huijuan Rong, Kathleen Baird
BACKGROUND: Maternal pushing during the second stage of labor could influence labor progress and maternal-neonatal outcomes. Although the image of health care providers directing the laboring women to push during the second stage of labor could be commonly observed globally, this practice is not sufficiently researched and is questioned regarding its effectiveness and outcomes on the mother and baby. Meanwhile, a strategy referred to as "spontaneous pushing," which supports women to push by following their bodily urges, has been evaluated in several trials...
March 26, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38528474/reproductive-factors-and-subsequent-pregnancy-outcomes-in-patients-with-prior-pregnancy-loss
#8
JOURNAL ARTICLE
Xin Yang, Fangxiang Mu, Jian Zhang, Liwei Yuan, Wei Zhang, Yanting Yang, Fang Wang
BACKGROUND: At present, individualized interventions can be given to patients with a clear etiology of pregnancy loss to improve the subsequent pregnancy outcomes, but the current reproductive status of the patient cannot be changed. The aim of this study was to investigate the association between female reproductive status and subsequence pregnancy outcome in patients with prior pregnancy loss (PL). METHODS: A prospective, dynamic population cohort study was carried out at the Second Hospital of Lanzhou University...
March 25, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38527605/defining-success-after-surgical-treatment-of-stress-urinary-incontinence
#9
JOURNAL ARTICLE
Rubin Raju, Annetta M Madsen, Brian J Linder, John A Occhino, John B Gebhart, Michaela E McGree, Amy L Weaver, Emanuel C Trabuco
BACKGROUND: A consensus standardized definition of success after stress urinary incontinence surgical treatment is lacking, which precludes comparisons between studies and affects patient counseling. OBJECTIVES: To identify optimal patient-centric definition(s) of success after stress urinary incontinence surgical treatment and to compare the identified "more accurate" treatment success definitions with a commonly used composite definition of success (ie, no reported urine leakage, negative cough stress test result, and no retreatment)...
March 23, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38525626/implementing-e-motive-for-detection-and-treatment-of-postpartum-haemorrhage-in-south-africa
#10
JOURNAL ARTICLE
M Singata-Madliki, S Fawcus, N Moran, E Arends, E Muller, S Mandondo, G J Hofmeyr
Postpartum haemorrhage is the leading cause of preventable maternal mortality in South Africa. In a significant breakthrough in the management of PPH, the E-MOTIVE trial found that a multifaceted health service intervention reduced severe PPH after vaginal delivery by 60% in 78 hospitals in Nigeria, Kenya, Tanzania and SA. The E-MOTIVE approach comprises objective blood loss measurement monitored every 15 minutes during the first hour after delivery to detect PPH early and trigger a bundle of first-line treatments, including massaging the uterus, oxytocin infusion, tranexamic acid infusion, intravenous crystalloid fluids, examination for the cause, emptying the bladder and, if necessary, escalation of care...
December 4, 2023: South African Medical Journal
https://read.qxmd.com/read/38524189/reducing-trainee-mistakes-better-performance-with-changing-to-a-high-fidelity-simulation-system
#11
JOURNAL ARTICLE
Aino Ritva Weyers, Gabriel von Waldenfels, Pimrapat Gebert, Wolfgang Henrich, Larry Hinkson
BACKGROUND: Postpartum hemorrhage is a significant cause of both maternal morbidity and mortality worldwide and is increasing in incidence. This study aimed to assess improvement and identify shortcomings in trainee performance in different simulation systems in the management of postpartum hemorrhage. OBJECTIVE: To perform a pilot study evaluating and comparing high- and low-fidelity simulation models, assessing improvement in repeated performance with high-fidelity mode and identifying mistakes made assessed using Objective Structured Assessment of Technical Skills and thereby exploring what aspects of emergency management of postpartum hemorrhage should be prioritized in teaching settings and assessing what simulation setup is most effective in achieving competence...
May 2024: AJOG global reports
https://read.qxmd.com/read/38522950/influence-of-cancer-in-pregnancy-on-obstetric-and-neonatal-outcomes-an-observational-retrospective-cohort-study
#12
JOURNAL ARTICLE
Xuan Huang, Chen Zhang, Jialei Zhu, Yueyan Li, Jing Tang
OBJECTIVE: The study aimed to review the oncological characteristics and treatment of pregnancy-associated cancers and analyze the obstetric and neonatal outcomes to provide evidence-based recommendations for reproductive function preservation, oncological treatment, and obstetric management. METHODS: We conducted an observational retrospective cohort study among pregnant patients with cancer in 7 Chinese tertiary A hospitals from 2003 to 2021. We conducted multiple logistic regression to determine the influence of various factors on preterm birth and small-for-gestational-age infants, log-binomial regression to analyze temporal changes, and χ² tests to explore the effects of cancer type/treatment...
March 11, 2024: Journal of Gynecologic Oncology
https://read.qxmd.com/read/38522420/a-learning-curve-for-first-trimester-anatomy-ultrasound-in-obese-patients
#13
Cara Buskmiller, Sarah E Toates, Vanessa Rodriguez, Edgar Hernandez-Andrade
OBJECTIVES: A recent randomized controlled trial of first-trimester anatomy ultrasound in obese women found some advantages to using this technique in this population, but some aspects of feasibility were not clear, such as whether first-trimester ultrasound can be brought outside of a research setting. The learning curve for first-trimester anatomy has been described in the general population, but a learning curve has not been described for this technique in obese patients. This study sought to describe a learning curve for first-trimester anatomy ultrasounds in obese patients in an operator familiar with the basics of first-trimester imaging...
March 22, 2024: Gynecologic and Obstetric Investigation
https://read.qxmd.com/read/38521925/development-validation-and-reliability-of-the-chrononutrition-profile-questionnaire-pregnancy-cpq-p
#14
JOURNAL ARTICLE
Ee Yin Kok, Satvinder Kaur, Nurul Husna Mohd Shukri, Nurliyana Abdul Razak, Masaki Takahashi
BACKGROUND: During pregnancy, physiological changes can affect eating and sleeping habits, which may eventually have negative consequences for maternal and foetal health. To better understand these changes, it is essential to develop a reliable questionnaire that addresses lifestyle habits such as snacking and daytime napping. This study aimed to determine the validity and reliability of the Chrononutrition Profile Questionnaire-Pregnancy (CPQ-P). METHODS: A total of 399 women in their second and third trimester of pregnancy were recruited from government maternal and child health clinics in Kuala Lumpur and Putrajaya and completed a self-administered online questionnaire...
March 23, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38521233/preoperative-free-access-to-water-compared-to-fasting-for-planned-cesarean-under-spinal-anesthesia-a-randomized-controlled-trial
#15
JOURNAL ARTICLE
Yee Ling Ng, Sabeetha Segaran, Carolyn Chue Wai Yim, Boon Kiong Lim, Mukhri Hamdan, Farah Gan, Peng Chiong Tan
BACKGROUND: Contemporary guidance for preoperative feeding allows solids up to six hours and clear fluid up to two hours before anesthesia. Clinical trial evidence to support this approach for cesarean section is lacking. Many medical practitioners continue to follow conservative policies of no intake from midnight to the time of surgery, especially in pregnant women. OBJECTIVE: To evaluate the pragmatic approach of permitting free access to water to the point when the operating theater call to dispatch the woman compared to fasting from midnight in preoperative oral intake restriction for planned cesarean under spinal anesthesia on perioperative vomiting and maternal satisfaction...
March 21, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38521232/reproductive-and-obstetric-outcomes-after-treatment-of-retained-products-of-conception-hysteroscopic-removal-versus-ultrasound-guided-electric-vacuum-aspiration-a-prospective-follow-up-study
#16
JOURNAL ARTICLE
Liselot P Wagenaar, Wouter L J van Vugt, Aleida G Huppelschoten, Celine M Radder, Louisette W Peters, Steven Weyers, Steffi van Wessel, Benedictus C Schoot, Tjalina W O Hamerlynck, Huib A van Vliet
BACKGROUND: Traditionally, curettage is the most widely performed surgical intervention used to remove retained products of conception. However, hysteroscopic removal is increasingly performed as an alternative due to the potentially lower risk of intrauterine adhesions and higher rates of complete removal. Until recently, studies comparing curettage with hysteroscopic removal regarding reproductive and obstetric outcomes were limited, and data conflicting. OBJECTIVE: To study reproductive and obstetric outcomes in women wishing to conceive after removal of retained products of conception by hysteroscopy or ultrasound-guided electric vacuum aspiration...
March 21, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38521126/-usefulness-of-ultrasound-measurement-of-the-lower-uterine-segment-before-delivery-of-women-with-a-prior-cesarean-literature-review
#17
JOURNAL ARTICLE
Patrick Rozenberg
Identifying women with a history of cesarean delivery and at real risk for uterine rupture is an important aim in obstetric care. It is with this objective that different authors have evaluated the interest of ultrasound for predicting the risk of a cesarean scar defect by measuring the thickness of the lower uterine segment. The literature is sparse and subject to numerous biases because they are mainly prospective cohort studies with small numbers. However, the results are concordant: Ultrasound measurements of lower uterine segment thickness are strongly correlated with the operative findings observed during cesarean delivery...
March 21, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38521086/pembrolizumab-or-placebo-with-chemoradiotherapy-followed-by-pembrolizumab-or-placebo-for-newly-diagnosed-high-risk-locally-advanced-cervical-cancer-engot-cx11-gog-3047-keynote-a18-a-randomised-double-blind-phase-3-clinical-trial
#18
JOURNAL ARTICLE
Domenica Lorusso, Yang Xiang, Kosei Hasegawa, Giovanni Scambia, Manuel Leiva, Pier Ramos-Elias, Alejandro Acevedo, Vladyslav Sukhin, Noelle Cloven, Andrea J Pereira de Santana Gomes, Fernando Contreras Mejía, Ari Reiss, Ali Ayhan, Jung-Yun Lee, Valeriya Saevets, Flora Zagouri, Lucy Gilbert, Jalid Sehouli, Ekkasit Tharavichitkul, Kristina Lindemann, Roberta Lazzari, Chih-Long Chang, Rudolf Lampé, Hong Zhu, Ana Oaknin, Melissa Christiaens, Stephan Polterauer, Tomoka Usami, Kan Li, Karin Yamada, Sarper Toker, Stephen M Keefe, Sandro Pignata, Linda R Duska
BACKGROUND: Pembrolizumab has shown efficacy in persistent, recurrent, or metastatic cervical cancer. The effect of chemoradiotherapy might be enhanced by immunotherapy. In this phase 3 trial, we assessed the efficacy and safety of adding pembrolizumab to chemoradiotherapy in locally advanced cervical cancer. METHODS: In this randomised, double-blind, placebo-controlled, phase 3 ENGOT-cx11/GOG-3047/KEYNOTE-A18 clinical trial, adults (age ≥18 years) at 176 medical centres in 30 countries with newly diagnosed, high-risk, locally advanced cervical cancer were randomly assigned (1:1) using an interactive voice-response system with integrated web response to receive 5 cycles of pembrolizumab (200 mg) or placebo every 3 weeks plus chemoradiotherapy, followed by 15 cycles of pembrolizumab (400 mg) or placebo every 6 weeks...
March 20, 2024: Lancet
https://read.qxmd.com/read/38520066/the-endometrial-transcriptome-of-infertile-women-with-and-without-implantation-failure
#19
JOURNAL ARTICLE
Bich Ngoc Bui, Viktorija Kukushkina, Alvin Meltsov, Catharina Olsen, Nienke van Hoogenhuijze, Signe Altmäe, Femke Mol, Gijs Teklenburg, Jan-Peter de Bruin, Dagmar Besselink, Linda Stevens Brentjens, Darina Obukhova, Masoud Zamani Esteki, Ron van Golde, Andrea Romano, Triin Laisk, Gaby Steba, Shari Mackens, Andres Salumets, Frank Broekmans
INTRODUCTION: Implantation failure after transferring morphologically "good-quality" embryos in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) may be explained by impaired endometrial receptivity. Analyzing the endometrial transcriptome analysis may reveal the underlying processes and could help in guiding prognosis and using targeted interventions for infertility. This exploratory study investigated whether the endometrial transcriptome profile was associated with short-term or long-term implantation outcomes (ie success or failure)...
March 22, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38518811/systematic-review-of-barriers-to-and-facilitators-of-screening-for-postpartum-depression-at-well-child-visits-in-the-united-states
#20
REVIEW
Marcy Hanson, Tracy Hellem, Julie Alexander-Ruff, Sophia R Newcomer
OBJECTIVE: To identify and evaluate barriers to and facilitators of screening for postpartum depression (PPD) during well-child visits in the United States. Additionally, to describe prior work on PPD screening tool evaluation and outcomes from PPD screenings conducted within the well-child setting. DATA SOURCES: A systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Five databases (Pub Med, PsycINFO, Web of Science, CINAHL, and Cochrane Library) were searched...
March 19, 2024: Nursing for Women's Health
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