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https://www.readbyqxmd.com/read/28079777/it-s-all-how-you-spin-it-interpretive-bias-in-research-findings-in-the-obstetrics-and-gynecology-literature
#1
Mark Turrentine
Scientific publications can be subject to varying degrees of interpretive bias, also known as spin. The rate of spin in randomized controlled trials (RCTs) with nonsignificant primary outcomes in the general obstetrics and gynecology literature is unknown. A decade (January 2006 through December 2015) of the tables of contents of Obstetrics & Gynecology and the American Journal of Obstetrics & Gynecology were screened, with 503 RCTs identified. Limiting assessment to only parallel-group RCTs with a nonsignificant primary outcome (P≥...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28079555/epidural-labor-analgesia-and-maternal-fever
#2
Emily E Sharpe, Katherine W Arendt
Women receiving an epidural for labor analgesia are at increased risk for intrapartum fever. This relationship has been supported by observational, before and after, and randomized controlled trials. The etiology is not well understood but is likely a result of noninfectious inflammation as studies have found women with fever have higher levels of inflammatory markers. Maternal pyrexia may change obstetric management and women are more likely to receive antibiotics or undergo cesarean delivery. Maternal pyrexia is associated with adverse neonatal outcomes...
January 10, 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28076940/cervical-ripening-with-self-administered-iso-sorbide-mononitrate-vaginally-in-uncomplicated-singleton-pregnancies-at-39-weeks-gestation-a-double-blind-randomised-controlled-trial
#3
RANDOMIZED CONTROLLED TRIAL
K Attanayake, M Goonewardene
Introduction: Vaginal iso sorbide mononitrate (ISMN) is effective in pre induction cervical ripening in post dated pregnancies. Objectives: To determine the effectiveness and acceptability of ISMN self-administered vaginally at home, in causing cervical ripening in uncomplicated singleton pregnancies at 39 weeks gestation. Methods: Consecutive women with uncomplicated singleton pregnancies, presenting between 01 October 2013 and 31 March 2014, with a modified Bishop score (MBS) of < 5 at a gestational age (GA) of 273 days to the University Obstetric Unit of Teaching Hospital Mahamodera Galle, were allocated by stratified (primip/multip) block randomisation to self-administer vaginally at home every other day, five doses of 60 mg of sustained release form of ISMN (ISMN-SR); (n = 72, cases), or pyridoxine 10 mgs (n=72, controls), from GA 273 to 282 days...
30, 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28075507/labour-induction-near-term-for-women-aged-35-or-over-an-economic-evaluation
#4
Kate F Walker, Melina Dritsaki, George Bugg, Marion Macpherson, Carol McCormick, Nicky Grace, Chris Wildsmith, Lucy Bradshaw, Gordon Cs Smith, James G Thornton
OBJECTIVE: Induction of labour at 39 weeks for nulliparous women aged 35 years and over may prevent stillbirths and does not increase caesarean births, so it may be popular. But the overall costs and benefits of such a policy have not been compared. DESIGN: A cost-utility analysis alongside a randomised controlled trial (the 35/39 trial). SETTING: Obstetric departments of 38 UK National Health Service hospitals and one UK primary care trust...
January 11, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28073296/the-microbiome-and-complement-activation
#5
Alexis B Dunn, Anne L Dunlop, Carol J Hogue, Andrew Miller, Elizabeth J Corwin
Preterm birth (PTB, <37 completed weeks' gestation) is one of the leading obstetrical problems in the United States, affecting approximately one of every nine births. Even more concerning are the persistent racial disparities in PTB, with particularly high rates among African Americans. There are several recognized pathophysiologic pathways to PTB, including infection and/or exaggerated systemic or local inflammation. Intrauterine infection is a causal factor linked to PTB thought to result most commonly from inflammatory processes triggered by microbial invasion of bacteria ascending from the vaginal microbiome...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28070251/comparison-between-vaginal-royal-jelly-and-vaginal-estrogen-effects-on-quality-of-life-and-vaginal-atrophy-in-postmenopausal-women-a-clinical-trial-study
#6
Fatemeh Seyyedi, Mahmoud Rafiean Kopaei, Sepideh Miraj
OBJECTIVE: This study was conducted to evaluate the therapeutic effects of vaginal royal jelly and vaginal estrogen on quality of life and vaginal atrophy in postmenopausal women. METHODS: This double-blind randomized controlled clinical trial was carried out at gynecology and obstetrics clinics of Hajar Hospital of Shahrekord University of Medical Sciences (Iran) from January 2013 to January 2014. The study was conducted on married postmenopausal women between 50 and 65 years old...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28069180/investigation-of-the-microbiota-of-the-reproductive-tract-in-women-undergoing-a-total-hysterectomy-and-bilateral-salpingo-oopherectomy
#7
Shana M Miles, Britney L Hardy, D Scott Merrell
OBJECTIVE: To conduct a pilot study to investigate the possible presence of bacteria throughout the female reproductive tract and to make a preliminary assessment of whether there are differences in the composition of the microbial communities between these body sites and/or between patients. DESIGN: Prospective pilot study followed by 16S amplification and high-throughput sequencing. SETTING: Tertiary care military hospital. PATIENT(S): A total of 10 women underwent a total hysterectomy with bilateral salpingo-oopherectomy; tissue samples were collected from the vagina, resected cervix, uterus, fallopian tubes, and ovaries...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28063907/impact-of-video-coaching-on-gynecologic-resident-laparoscopic-suturing-a-randomized-controlled-trial
#8
Noah B Rindos, Minhnoi Wroble-Biglan, Amanda Ecker, Ted T Lee, Nicole M Donnellan
STUDY OBJECTIVE: To determine if the addition of video coaching to an OBGYN resident laparoscopic simulation curriculum improves acquisition of suturing skills. DESIGN: Randomized controlled trial DESIGN CLASSIFICATION: I SETTING: Academic teaching hospital with a residency program in obstetrics and gynecology PATIENTS: Twenty OBGYN residents undergoing a 4-week laparoscopic simulation curriculum were video-recorded weekly performing a suturing task on a validated vaginal cuff model...
January 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28063805/effect-of-prenatal-counseling-on-breastfeeding-rates-in-mothers-of%C3%A2-twins
#9
Fernanda Cristina Ferreira Mikami, Maria de Lourdes Brizot, Terezinha Hideco Tase, Elizabeth Saccuman, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib
OBJECTIVE: To investigate the effect of antenatal breastfeeding counseling on the breastfeeding rates for women who give birth to twins. DESIGN: Prospective randomized trial. SETTING: Multiple Pregnancy Unit, Obstetrics Department, University of São Paulo, Brazil. PARTICIPANTS: A total of 171 mothers of twins and their 342 infants. METHODS: The participants were randomized into the prenatal counseling group (PCG) or control group (CG)...
January 5, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28062025/amniotic-fluid-technical-update-on-physiology-and-measurement
#10
Kenneth I Lim, Kimberly Butt, Kentia Naud, Mila Smithies
OBJECTIVE: OUTCOMES: EVIDENCE: A MEDLINE and KFINDER search was used to identify relevant articles, with review of bibliography identified article including Cochrane reviews and recent review articles. VALUES: The evidence collected was reviewed by the Diagnostic Imaging Committee of the Society of Obstetricians and Gynecologists of Canada. The recommendations were made according to the guidelines developed by The Canadian Task Force on Preventative Health Care (Table 1)...
January 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28061783/improving-the-knowledge-of-labour-and-delivery-nurses-in-india-a-randomized-controlled-trial-of-mentoring-and-case-sheets-in-primary-care-centres
#11
Janet Bradley, Krishnamurthy Jayanna, Souradet Shaw, Troy Cunningham, Elizabeth Fischer, Prem Mony, B M Ramesh, Stephen Moses, Lisa Avery, Maryanne Crockett, James F Blanchard
BACKGROUND: Birthing in health facilities in India has increased over the last few years, yet maternal and neonatal mortality rates remain high. Clinical mentoring with case sheets or checklists for nurses is viewed as essential for on-going knowledge transfer, particularly where basic training is inadequate. This paper summarizes a study of the effect of such a programme on staff knowledge and skills in a randomized trial of 295 nurses working in 108 Primary Health Centres (PHCs) in Karnataka, India...
January 7, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28058505/a-randomized-controlled-trial-effects-of-a-prenatal-depression-intervention-on-perinatal-outcomes-among-chinese-high-risk-pregnant-women-with-medically-defined-complications
#12
Ying Zhao, Michelle L Munro-Kramer, Shenxun Shi, Jing Wang, Jianfeng Luo
: Prenatal psychosocial health has been linked with health behaviors, maternal health, and birth outcomes. This randomized controlled trial evaluated the effects of a prenatal depression intervention on birth outcomes and maternal physical and psychological status at 42 days postpartum. Three hundred fifty-two high-risk pregnant women exposed to obstetric complications with an Edinburgh Postnatal Depression Scale (EPDS) ≥ 9 or a Postpartum Depression Screening Scale (PDSS) ≥ 60 were randomly assigned to the intervention group (n = 176) and control group (n = 176)...
January 5, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28057388/evaluation-of-focused-obstetric-ultrasound-examinations-by-health-care-personnel-in-the-democratic-republic-of-congo-guatemala-kenya-pakistan-and-zambia
#13
Robert O Nathan, Jonathan O Swanson, David L Swanson, Elizabeth M McClure, Victor Lokomba Bolamba, Adrien Lokangaka, Irma Sayury Pineda, Lester Figueroa, Walter López-Gomez, Ana Garces, David Muyodi, Fabian Esamai, Nancy Kanaiza, Waseem Mirza, Farnaz Naqvi, Sarah Saleem, Musaku Mwenechanya, Melody Chiwila, Dorothy Hamsumonde, Dennis D Wallace, Holly Franklin, Robert L Goldenberg
Prior studies have suggested that obstetrical (OB) ultrasound in low- and middle-income countries has aided in detection of high-risk conditions, which in turn could improve OB management. We are participating in a cluster-randomized clinical trial of OB ultrasound, which is designed to assess the effect of basic OB ultrasound on maternal mortality, fetal mortality, neonatal mortality, and maternal near-miss in 5 low-income countries. We designed a 2-week course in basic OB ultrasound, followed by 12 weeks of oversight, to train health care professionals with no prior ultrasound experience to perform basic OB ultrasound to screen for high-risk pregnancies...
November 10, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28044181/mr-pelvimetry-prognosis-for-successful-vaginal-delivery-in-patients-with-suspected-fetopelvic-disproportion-or-breech-presentation-at-term
#14
Marie Franz, Amanda von Bismarck, Maria Delius, Birgit Ertl-Wagner, Charlotte Deppe, Sven Mahner, Uwe Hasbargen, Christoph Hübener
PURPOSE: The purpose of this study was to correlate MR pelvimetric pelvic inlet measurements with mode of delivery and neonatal outcome in patients with suspected fetopelvic disproportion or breech presentation. METHODS: For this retrospective monocentric study, 237 consecutive MR pelvimetry reports (1999-2016) of pregnant women due to either suspected fetopelvic disproportion, pelvic deformation after trauma, or persistent breech presentation were retrieved from the radiologic database and matched with corresponding information from the obstetric database...
January 2, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28042167/diagnosis-and-therapy-of-female-pelvic-organ-prolapse-guideline-of-the-dggg-sggg-and-oeggg-s2e-level-awmf-registry-number-015-006-april-2016
#15
K Baeßler, T Aigmüller, S Albrich, C Anthuber, D Finas, T Fink, C Fünfgeld, B Gabriel, U Henscher, F H Hetzer, M Hübner, B Junginger, K Jundt, S Kropshofer, A Kuhn, L Logé, G Nauman, U Peschers, T Pfiffer, O Schwandner, A Strauss, R Tunn, V Viereck
Aims: The aim was to establish an official interdisciplinary guideline, published and coordinated by the German Society of Gynecology and Obstetrics (DGGG). The guideline was developed for use in German-speaking countries. In addition to the Germany Society of Gynecology and Obstetrics, the guideline has also been approved by the Swiss Society of Gynecology and Obstetrics (SGGG) and the Austrian Society of Gynecology and Obstetrics (OEGGG). This is a guideline published and coordinated by the DGGG. The aim is to provide evidence-based recommendations obtained by evaluating the relevant literature for the diagnostic, conservative and surgical treatment of women with female pelvic organ prolapse with or without stress incontinence...
December 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28031304/web-based-quality-assurance-process-drives-improvements-in-obstetric-ultrasound-in-5-low-and-middle-income-countries
#16
Jonathan O Swanson, David Plotner, Holly L Franklin, David L Swanson, Victor Lokomba Bolamba, Adrien Lokangaka, Irma Sayury Pineda, Lester Figueroa, Ana Garces, David Muyodi, Fabian Esamai, Nancy Kanaiza, Waseem Mirza, Farnaz Naqvi, Sarah Saleem, Musaku Mwenechanya, Melody Chiwila, Dorothy Hamsumonde, Elizabeth M McClure, Robert L Goldenberg, Robert O Nathan
High quality is important in medical imaging, yet in many geographic areas, highly skilled sonographers are in short supply. Advances in Internet capacity along with the development of reliable portable ultrasounds have created an opportunity to provide centralized remote quality assurance (QA) for ultrasound exams performed at rural sites worldwide. We sought to harness these advances by developing a web-based tool to facilitate QA activities for newly trained sonographers who were taking part in a cluster randomized trial investigating the role of limited obstetric ultrasound to improve pregnancy outcomes in 5 low- and middle-income countries...
December 23, 2016: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28029178/exercise-during-pregnancy-and-risk-of-preterm-birth-in-overweight-and-obese-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
Elena Rita Magro-Malosso, Gabriele Saccone, Daniele Di Mascio, Mariarosaria Di Tommaso, Vincenzo Berghella
INTRODUCTION: The incidence of overweight and obesity in pregnancy has risen significantly in the last decades. Overweight and obesity have been shown to increase the risk for some adverse obstetric outcome. Lifestyle interventions, such as diet, physical activity and behavior changes, may reduce these risks promoting weight loss and/or preventing excessive weight gain. The possible impact of exercise on the risk of preterm birth (PTB) in overweight or obese women is controversial. Therefore, the aim of our study was to evaluate the effect of exercise on the risk of PTB in overweight or obese pregnant women...
December 28, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28005272/prophylactic-versus-selective-blood-transfusion-for-sickle-cell-disease-in-pregnancy
#18
REVIEW
Babasola O Okusanya, Olufemi T Oladapo
BACKGROUND: Pregnant women with sickle cell disease (HbSS, HbSC and HbSβThal) may require blood transfusion to prevent severe anaemia or to manage potential medical complications. Preventive blood transfusion in the absence of complications starting from the early weeks of pregnancy or blood transfusion only for medical or obstetric indications have been used as management policies. There is currently no consensus on the blood transfusion policy that guarantees optimal clinical benefits with minimal risks for such women and their babies...
22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27998899/effect-of-the-type-of-maternal-pushing-during-the-second-stage-of-labour-on-obstetric-and-neonatal-outcome-a-multicentre-randomised-trial-the-eole-study-protocol
#19
Chloé Barasinski, Françoise Vendittelli
INTRODUCTION: The scientific data currently available do not allow any definitive conclusion to be reached about what type of pushing should be recommended to women during the second stage of labour. The objective of this trial is to assess and compare the effectiveness of directed open-glottis pushing versus directed closed-glottis pushing. Secondary objectives are to assess, according to the type of pushing: immediate maternal and neonatal morbidity, intermediate-term maternal pelvic floor morbidity, uncomplicated birth, and women's satisfaction at 4 weeks post partum...
December 20, 2016: BMJ Open
https://www.readbyqxmd.com/read/27986648/associations-between-maternal-characteristics-and-women-s-responses-to-acupuncture-during-labour-a-secondary-analysis-from-a-randomised-controlled-trial
#20
Linda Vixner, Erica Schytt, Lena B Mårtensson
BACKGROUND: Patient characteristics are modulators of pain experience after acupuncture treatment for chronic pain. Whether this also applies to labour pain is unknown. AIM: To examine for associations between maternal characteristics and response to acupuncture in terms of labour pain intensity in close proximity to the treatment (within 60 min) and over a longer time period (up to 240 min), and whether or not epidural analgesia is used, before and after adjustment for obstetric status upon admission to the labour ward...
December 16, 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
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