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https://www.readbyqxmd.com/read/29128233/cementless-total-knee-arthroplasty-in-knee-osteonecrosis-demonstrated-excellent-survivorship-and-outcomes-at-three-year-minimum-follow-up
#1
Assem A Sultan, Anton Khlopas, Nipun Sodhi, Mark L Denzine, Prem N Ramkumar, Steven F Harwin, Michael A Mont
BACKGROUND: Lack of consensus exists on the use of cementless total knee arthroplasty (TKA) in patients with knee osteonecrosis. Therefore, this study was conducted to evaluate (1) implant survivorship; (2) clinical outcomes and complications; and (3) radiographic outcomes of primary cementless TKA in knee osteonecrosis. METHODS: This study included 46 patients (49 knees) who had knee osteonecrosis and underwent primary cementless TKA and had a mean follow-up of 44 months (range 36-96)...
November 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29121696/quadriceps-and-hamstring-muscle-strength-improves-after-unicompartmental-knee-arthroplasty
#2
Jennifer Kurowicki, Anton Khlopas, Nipun Sodhi, Jared M Newman, Assem A Sultan, Morad Chughtai, Anil Bhave, Martin Roche, Peter M Bonutti, Michael A Mont
INTRODUCTION: The ability to reach functional capacity following knee arthroplasty depends on the strength of the quadriceps and hamstring muscles. Following total knee arthroplasty, weakness of these muscles can persist for up to one year postoperatively; however, this phenomenon is not well-studied in unicompartmental knee arthroplasty (UKA) patients. Therefore, we assessed: 1) quadriceps muscle strength; 2) hamstring muscle strength; and 3) correlation to functional outcomes. MATERIALS AND METHODS: A review of all patients with medial compartment osteoarthritis treated with UKA at a minimum of one-year follow-up was performed...
November 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29073001/kearns-sayre-syndrome-looking-beyond-a-v-conduction
#3
Mani Ram Krishna
A 15-year-old boy was diagnosed with Kayne Sayre Syndrome. He presented with pigmentary retinopathy, progressive ophthalmoplegia and complete heart block. He received a transvenous dual chamber pacemaker. Two years later he died suddenly while at home. This case highlights the importance of recognizing mechanisms other than heart block as a cause of sudden death in a patient with KSS.
May 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29071356/no-improvement-in-reducing-outliers-in-coronal-axis-alignment-with-patient-specific-instrumentation
#4
Uwe Maus, Carlos J Marques, David Scheunemann, Frank Lampe, Djordje Lazovic, Hagen Hommel, Dennis Vogel, Martin Haunschild, Tilman Pfitzner
PURPOSE AND HYPOTHESIS: Patient-specific instrumentation (PSI) uses 3D preoperative imaging to produce individualized cutting blocks specific to patients' anatomy and according to the preoperative plan with the aim to reduce the number of mechanical leg alignment (MLA) outliers, to improve implant positioning and to decrease surgery time. The primary purpose of this study was to investigate the efficacy of a specific PSI in comparison with standard instrumentation (SI) in reducing the number of MLA outliers...
October 25, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29065953/lemborexant-a-dual-orexin-receptor-antagonist-dora-for-the-treatment-of-insomnia-disorder-results-from-a-bayesian-adaptive-randomized-double-blind-placebo-controlled-study
#5
Patricia Murphy, Margaret Moline, David Mayleben, Russell Rosenberg, Gary Zammit, Kate Pinner, Shobha Dhadda, Quan Hong, Luigi Giorgi, Andrew Satlin
STUDY OBJECTIVES: To identify dose(s) of lemborexant that maximize insomnia treatment efficacy while minimizing next-morning residual sleepiness and evaluate lemborexant effects on polysomnography (PSG) measures (sleep efficiency [SE], latency to persistent sleep [LPS], and wake after sleep onset [WASO]) at the beginning and end of treatment. METHODS: Adults and elderly subjects with insomnia disorder per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition were enrolled in a multicenter, randomized, double-blind, placebo-controlled, Bayesian, adaptive, parallel-group study, receiving lemborexant (1, 2...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29062820/comparison-of-puddu-osteotomy-with-or-without-autologous-bone-grafting-a-prospective-clinical-trial
#6
Marcus Ceregatti Passarelli, José Roberto Tonelli Filho, Felipe Augusto Mendes Brizzi, Gustavo Constantino de Campos, Alessandro Rozim Zorzi, João Batista de Miranda
OBJECTIVES: To test the hypothesis that autologous iliac bone grafts do not enhance clinical results and do not decrease complication rates in patients undergoing medial opening-wedge high tibial osteotomy. METHODS: Forty patients allocated in a randomized, two-armed, double-blinded clinical trial were evaluated between 2007 and 2010. One group received bone graft, and the other group was left without filling the osteotomy defect. The primary outcome was the Knee Society Score...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29060505/three-drowsiness-categories-assessment-by-electroencephalogram-in-driving-simulator-environment
#7
Izzat A Akbar, Arthur M Rumagit, Mitaku Utsunomiya, Takamasa Morie, Tomohiko Igasaki
Traffic accidents remain one of the most critical issues in many countries. One of the major causes of traffic accidents is drowsiness while driving. Since drowsiness is related to human physiological conditions, drowsiness is hard to prevent. Several studies have been conducted in assessing drowsiness, especially in a driving environment. One of the common methods used is the electroencephalogram (EEG). It is known that drowsiness occurs in the central nervous system; thus, estimating drowsiness using EEG is the promising way to assess drowsiness accurately...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29045970/-unilateral-patellar-resurfacing-in-bilateral-total-knee-arthroplasty-a-randomized-controlled-study
#8
J F Wang, Z Li, K S Zhang, F Yuan, R J Li, Q J Zhong, Z P Guan
OBJECTIVE: To perform unilateral patellar resurfacing and contralateral patellar retention in bilateral total knee arthroplasty (TKA) randomly, and to compare the clinical effects of patellar retention with patellar resurfacing in TKA. METHODS: In the study, 14 bilateral knee osteoarthritis (OA) patients were randomized in the bilateral TKA to receive unilateral patellar resurfacing and contralateral patellar retention, including 28 knees, all were females, 53 to 78 years old, with average (66...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29043087/sleepiness-while-driving-and-shiftwork-patterns-among-korean-bus-drivers
#9
Seyoung Lee, Hyoung-Ryoul Kim, Junsu Byun, Taewon Jang
BACKGROUND: Sleepiness while driving has been regarded as a major cause of death due to traffic accidents. We compared the degree of sleepiness across five different working time periods (first, morning, post-lunch, afternoon, and last) among Korean bus drivers with different shift types (Daily two shift/Alternating day shift). METHOD: We interviewed 332 bus drivers with two shift types (Daily two shift, 128; Alternating day shift, 204). The questionnaire included demographic information (age, alcohol consumption and history of disease), a sleep disorder diagnosed by a doctor, job duration, the number of workdays in the past month, average working hours per workday and week, sleepiness while driving (Karolinska Sleepiness Scale), and sleeping time for both workdays and off-days...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29041970/comparison-of-the-efficacy-of-static-versus-articular-spacers-in-two-stage-revision-surgery-for-the-treatment-of-infection-following-total-knee-arthroplasty-a-meta-analysis
#10
Hai Ding, Jian Yao, Wenju Chang, Fendou Liu
BACKGROUND: The aim of this study was to compare the outcomes of static versus articular spacers in two-stage reimplantation for the treatment of infected total knee arthroplasty (TKA). METHODS: The literature regarding the articulating and static spacers for treating infected TKA were searched in PubMed, Embase, Cochrane Library, Chinese Periodical Full-Text Database of CNKI, and Wanfang database. Data were extracted according to the inclusion and exclusion criteria and analyzed by Review Manager 5...
October 17, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29032861/patellar-resurfacing-in-total-knee-arthroplasty-systematic-review-and-meta-analysis
#11
REVIEW
Umile G Longo, Mauro Ciuffreda, Nicholas Mannering, Valerio D'Andrea, Matteo Cimmino, Vincenzo Denaro
BACKGROUND: Patellar resurfacing in total knee arthroplasty remains controversial. The aim of this study is to evaluate this technique through an analysis of comparative studies in the current literature. METHODS: We performed a comprehensive search of PubMed, MEDLINE, Cochrane, CINAHL, and EMBASE databases using various combinations of the keywords "Knee," "Replacement," "Prosthesis," "Patella," "Resurfacing," and "Arthroplasty." All articles relevant to the subject were retrieved, and their bibliographies were hand searched for further references relevant to primary patellar resurfacing in total knee arthroplasty...
September 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29032478/total-knee-arthroplasty-in-patients-with-a-history-of-illicit-intravenous-drug-abuse
#12
David E Bauer, Andreas Hingsammer, Lukas Ernstbrunner, Alexander Aichmair, Andrea B Rosskopf, Franziska Eckers, Karl Wieser, Sandro F Fucentese
PURPOSE: Injection drug users are at high risk for both infection with blood-borne pathogens, namely, human immune deficiency virus (HIV), hepatitis-B, -C virus, various bacterial infections, as well as early primary and secondary joint degeneration. When total knee arthroplasty (TKA) is anticipated the risk of septic complications is a major concern. The purpose of this study was to assess the clinical and radiographic outcome of patients with a history of intravenous drug use after total knee arthroplasty...
October 14, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29026941/neutral-alignment-leads-to-higher-knee-society-scores-after-total-knee-arthroplasty-in-preoperatively-non-varus-patients-a-prospective-clinical-study-using-3d-ct
#13
Omer Slevin, Anna Hirschmann, Filippo F Schiapparelli, Felix Amsler, Rolf W Huegli, Michael T Hirschmann
PURPOSE: The optimal coronal alignment is still under debate. However, in most of the studies, alignment was only assessed using radiographs, which are not accurate enough for assessment of tibial and femoral TKA position. The primary purpose of this study was to assess the relationship between coronal TKA alignment using 3D-reconstructed CTs and clinical outcome in patients with preoperative varus in comparison with patients with natural or valgus deformity. It was the hypothesis that neutral limb alignment shows a better outcome after TKA...
October 12, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29021089/patellofemoral-arthritis-treated-with-resurfacing-implant-clinical-outcome-and-complications-at-a-minimum-two-year-follow-up
#14
Juan Pablo Zicaro, Carlos Yacuzzi, Juan Astoul Bonorino, Lisandro Carbo, Matias Costa-Paz
BACKGROUND: This study evaluated the clinical and radiographic outcomes of a series of patients treated with an anatomic inlay resurfacing implant, with a minimum two-year follow-up. METHODS: Fifteen patients underwent patellofemoral-resurfacing procedures using a HemiCAP Wave Patellofemoral Inlay Resurfacing implant from 2010 to 2013. Clinical outcomes included: Visual Analog Scale (VAS), Lysholm score, Knee Society Score (KSS), and evaluation of Kujala, and Hospital for Special Surgery Patellofemoral score (HSS-PF)...
October 8, 2017: Knee
https://www.readbyqxmd.com/read/28987265/performance-and-sleepiness-in-nurses-working-12-h-day-shifts-or-night-shifts-in-a-community-hospital
#15
Marian Wilson, Regan Permito, Ashley English, Sandra Albritton, Carlana Coogle, Hans P A Van Dongen
Hospitals are around-the-clock operations and nurses are required to care for patients night and day. The nursing shortage and desire for a more balanced work-to-home life has popularized 12-h shifts for nurses. The present study investigated sleep/wake cycles and fatigue levels in 22 nurses working 12-h shifts, comparing day versus night shifts. Nurses (11day shift and 11 night shift) were recruited from a suburban acute-care medical center. Participants wore a wrist activity monitor and kept a diary to track their sleep/wake cycles for 2 weeks...
October 5, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28969683/clinical-and-radiological-results-of-cruciate-retaining-total-knee-arthroplasty-with-the-nexgen%C3%A2-cr-system-comparison-of-patellar-resurfacing-versus-retention-with-more-than-14%C3%A2-years-of-follow-up
#16
Keun Churl Chun, Sung Hyun Lee, Jong Seok Baik, Seng Hwan Kook, Joung Kyue Han, Churl Hong Chun
BACKGROUND: The purpose of this study is to analyze clinical and radiological outcomes of patients (with a minimum of 14 years of follow-up) who underwent cruciate-retaining (CR) total knee arthroplasty (TKA) using a NexGen®-CR, comparing a patellar resurfacing group with a patellar retention group. METHODS: From June 1996 to April 2002, 116 cases of TKA using a NexGen®-CR who had at least 14 years of follow-up were enrolled in this study. Among them, 68 cases had patellar resurfacing and 48 had patellar retention...
October 2, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28949419/both-modular-and-single-domain-type-i-polyketide-synthases-are-expressed-in-the-brevetoxin-producing-dinoflagellate-karenia-brevis-dinophyceae
#17
Frances M Van Dolah, Gurjeet S Kohli, Jeanine S Morey, Shauna A Murray
Dinoflagellates are prolific producers of polyketide compounds, many of which are potent toxins with adverse impacts on human and marine animal health. To identify polyketide synthase (PKS) genes in the brevetoxin-producing dinoflagellate, Karenia brevis, we assembled a transcriptome from 595 million Illumina reads, sampled under different growth conditions. The assembly included 125,687 transcripts greater than 300 nt in length, with over half having >100x coverage. We found 121 transcripts encoding Type I ketosynthase (KS) domains, of which 99 encoded single KS domains, while 22 contained multiple KS domains arranged in 1-3 protein modules...
September 26, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/28939967/no-influence-of-obesity-on-survival-of-cementless-posterior-stabilised-rotating-platform-implants
#18
Romain Gaillard, Thierry Gaillard, Stephane Denjean, Sebastien Lustig
INTRODUCTION: This study compares survival and outcomes in four total knee arthroplasty (TKA) populations defined by baseline body mass index (BMI). We hypothesised that there would be no difference in survival between the groups. MATERIALS AND METHODS: Using an initial cohort of 1059 TKAs, BMI was systematically measured prior to surgery. A retrospective study was conducted and patients were accordingly allocated to four groups: normal or underweight (BMI < 25; n = 111), overweight (25 ≤ BMI < 30; n = 417), moderately obese (30 ≤ BMI < 35; n = 330) and severely or morbidly obese (BMI ≥ 35; n = 201)...
September 22, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28932491/osteophytes-removal-in-patella-versus-lateral-facetectomy-of-the-patella-in-patella-retaining-total-knee-arthroplasty
#19
Mehdi Moghtadaei, Mohammad Reza Miniator Sajadi, Hossein Farahini, Ali Yeganeh
BACKGROUND: In this study, the results of the partial lateral facetectomy of the patella to better patellofemoral motion and congruence are compared with the results of the osteophyte removal of the patella and neurectomy only in total knee arthroplasty (TKA). METHODS: Data from 55 patients undergoing TKA with osteophytes removal of the patella and neurectomy only, and those undergoing osteophytes removal of the patella and neurectomy and partial lateral facetectomy were reviewed retrospectively...
March 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28918523/focal-metallic-inlay-resurfacing-prosthesis-for-the-treatment-of-localized-cartilage-defects-of-the-femoral-condyles-a-systematic-review-of-clinical-studies
#20
REVIEW
Andreas Fuchs, Helge Eberbach, Kaywan Izadpanah, Gerrit Bode, Norbert P Südkamp, Matthias J Feucht
PURPOSE: To systematically review the results of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles. METHODS: A systematic electronic search of the PubMed database and the Cochrane Library was performed in April 2017 to identify studies that reported clinical or radiographic outcome of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles...
September 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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