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https://www.readbyqxmd.com/read/29770589/short-term-follow-up-of-antibiotic-loaded-articulating-cement-spacers-in-two-stage-revision-of-infected-total-knee-arthroplasty-a-case-series
#1
Meng-Qiang Tian, Xian-Teng Yang, Xiao-Bin Tian, Yun-Bo Sun, Yuan-Hui Duan, Li Sun
OBJECTIVE: Infection of total knee arthroplasty (TKA) is a rare but devastating complication. Two-stage revision is an effective treatment for late infected TKA. This study aimed to assess the short-term results of two-stage revision using articulating antibiotic-loaded spacers. METHODS: Twenty-five patients (10 men and 15 women) were diagnosed with late infections after TKA and treated with two-stage revision from April 2006 to August 2010; 19 of these patients had TKA for osteoarthritis and 6 for rheumatoid arthritis...
May 17, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29767270/no-correlation-between-rotation-of-femoral-components-in-the-transverse-plane-and-clinical-outcome-after-total-knee-arthroplasty
#2
Roland Becker, Katharina Bäker, Hagen Hommel, Manfred Bernard, Sebastian Kopf
PURPOSE: It was hypothesized that malrotation of femoral component in total knee arthroplasty (TKA) will significantly impact clinical outcome. METHODS: Eighty-eight consecutive patients with primary osteoarthritis of the knee were prospectively evaluated. They received a cemented posterior stabilized TKA (NexGen, Zimmer/Biomet® Inc., Warsaw, IN, USA). The femoral component was placed in 3° of external rotation referenced to the posterior condylar line. Postoperatively, a CT scan was performed to evaluate rotation of femoral component in the transverse plane...
May 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29765985/effects-of-afternoon-nap-deprivation-on-adult-habitual-nappers-inhibition-functions
#3
Qingwei Chen, Taotao Ru, Minqi Yang, Pei Yan, Jinghua Li, Ying Yao, Xiaoran Li, Guofu Zhou
Multiple studies have established the effects of afternoon naps on cognition. However, relatively few studies have investigated the domain of executive functions. Moreover, the effects of napping on inhibition are far from conclusive. The present study employed adult habitual nappers to investigate the effects of afternoon nap deprivation on response-based inhibition assessed by a Go/No-go task and stimulus-based inhibition assessed by a Flanker task and on alertness assessed by a psychomotor vigilance test (PVT) and the Karolinska Sleepiness Scale (KSS)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29764618/investigating-daily-fatigue-scores-during-two-week-offshore-day-shifts
#4
Vanessa Riethmeister, Ute Bültmann, Marijke Gordijn, Sandra Brouwer, Michiel de Boer
OBJECTIVES: This study examined daily scores of fatigue and circadian rhythm markers over two-week offshore day shift periods. METHODS: A prospective cohort study among N = 60 offshore day-shift workers working two-week offshore shifts was conducted. Offshore day shifts lasted from 07:00 - 19:00 h. Fatigue was measured objectively with pre- and post-shift scores of the 3-minute psychomotor vigilance tasks (PVT-B) parameters (reaction times, number of lapses, errors and false starts) and subjectively with pre- and post-shift Karolinska Sleepiness Scale (KSS) ratings...
September 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29762282/uncemented-tantalum-monoblock-tibial-fixation-for-total-knee-arthroplasty-in-patients-less-than-60-years-of-age-mean-10-year-follow-up
#5
Christopher J DeFrancesco, José A Canseco, Charles L Nelson, Craig L Israelite, Atul F Kamath
BACKGROUND: Although tibial component loosening has been considered a concern after total knee arthroplasty without cement, such implants have been used in younger patients because of the potential for ingrowth and preservation of bone stock. However, mid-term and long-term studies of modern uncemented implants are lacking. We previously reported promising prospective 5-year outcomes after using an uncemented porous tantalum tibial component in patients who underwent surgery before the age of 60 years...
May 16, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29762280/long-term-outcomes-of-pedicled-gastrocnemius-flaps-in-total-knee-arthroplasty
#6
Matthew T Houdek, Eric R Wagner, Cody C Wyles, William S Harmsen, Arlen D Hanssen, Michael J Taunton, Steven L Moran
BACKGROUND: Deficient soft tissue following total knee arthroplasty (TKA) can jeopardize outcome. The gastrocnemius flap is an important means of providing coverage of a knee with deficient soft tissue. There is a paucity of long-term studies on the use of the gastrocnemius flap in the setting of TKA. The purpose of this study was to review the outcomes after the use of pedicled gastrocnemius flaps for coverage of a soft-tissue defect at the time of TKA. METHODS: Eighty-three patients in whom a gastrocnemius flap had been used to cover the site of a primary (n = 18) or revision (n = 65) TKA over a 25-year period were identified...
May 16, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29761973/-research-on-vigilance-detection-based-on-pulse-wave
#7
Yong Cao, Xuejun Jiao, Jinjin Pan, Jin Jiang, Jiahao Fu, Fenggang Xu, Hanjun Yang
This paper studied the rule for the change of vigilance based on pulse wave. 10 participants were recruited in a 95-minute Mackworth clock test (MCT) experiment. During the experiment, the vigilance of all participants were evaluated by Karolinska sleepiness scale (KSS) and Stanford sleepiness scale (SSS), and behavior data (the reaction time and the accuracy of target) and pulse wave signal of the participants were recorded simultaneously. The result indicated that vigilance of the participants can be divided into 3 classes: the first 30 minutes for high vigilance level, the middle 30 minutes for general vigilance level, and the last 30 minutes for low vigilance level...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29757693/a-rotator-cuff-tear-concomitant-with-shoulder-stiffness-is-associated-with-a-lower-retear-rate-after-1-stage-arthroscopic-surgery
#8
In-Bo Kim, Dong-Wook Jung
BACKGROUND: Few studies have reported on the radiological characteristics and repair integrity of coexistent rotator cuff tears (RCTs) and shoulder stiffness after simultaneous arthroscopic rotator cuff repair and capsular release. PURPOSE: To evaluate the radiological characteristics and repair integrity of 1-stage arthroscopic surgery of RCTs concomitant with shoulder stiffness. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: Among patients who underwent arthroscopic repair of full-thickness RCTs, the stiff group underwent simultaneous capsular release for shoulder stiffness, and the nonstiff group had no stiffness...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29732517/coronal-tibiofemoral-subluxation-is-correlated-to-correction-angle-in-medial-opening-wedge-high-tibial-osteotomy
#9
Hiroyasu Ogawa, Kazu Matsumoto, Haruhiko Akiyama
PURPOSE: This study aimed to analyse the change in coronal tibiofemoral (CTF) subluxation after high tibial osteotomy and to determine demographic variables associated with CTF subluxation. The change in CTF subluxation was hypothesised to be associated with the magnitude of correction of lower limb alignment and medial proximal tibial angle (MPTA). METHODS: A total of 103 consecutive knees in 86 patients who underwent medial opening wedge high tibial osteotomy for symptomatic medial compartment knee osteoarthritis were retrospectively analysed...
May 7, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29725747/no-difference-in-mid-term-survival-and-clinical-outcome-between-patient-specific-and-conventional-instrumented-total-knee-arthroplasty-a-randomized-controlled-trial
#10
M G M Schotanus, B Boonen, W van Weegen, H Hoekstra, R van Drumpt, R Borghans, R Vos, L van Rhijn, N P Kort
PURPOSE: The purpose of this multicentre prospective randomized controlled trial was to compare the survival rate and clinical outcome in total knee arthroplasty (TKA) after MRI-based patient-specific instruments (PSI) and conventional instruments 5 years after initial surgery. METHODS: At a mean follow-up of 5.1 years (0.4), 163 patients (90.6%) with a mean age of 71.8 years (8.7) were analysed. A survival analysis with revision of the TKA as endpoint was performed...
May 3, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29725177/involvement-of-the-spinal-cord-in-mitochondrial-disorders
#11
REVIEW
Josef Finsterer, Sinda Zarrouk-Mahjoub
This review aims at summarising and discussing the current status concerning the clinical presentation, pathogenesis, diagnosis, and treatment of spinal cord affection in mitochondrial disorders (MIDs). A literature search using the database Pubmed was carried out by application of appropriate search terms and their combinations. Involvement of the spinal cord in MIDs is more frequent than anticipated. It occurs in specific and non-specific MIDs. Among the specific MIDs it has been most frequently described in LBSL, LS, MERRF, KSS, IOSCA, MIRAS, and PCH and only rarely in MELAS, CPEO, and LHON...
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29696144/a-systematic-review-of-clinical-functional-outcomes-after-medial-stabilized-versus-non-medial-stabilized-total-knee-joint-replacement
#12
Tony Young, Michelle M Dowsey, Marcus Pandy, Peter F Choong
Background: Medial stabilized total knee joint replacement (TKJR) construct is designed to closely replicate the kinematics of the knee. Little is known regarding comparison of clinical functional outcomes of patients utilising validated patient reported outcome measures (PROM) after medial stabilized TKJR and other construct designs. Purpose: To perform a systematic review of the available literature related to the assessment of clinical functional outcomes following a TKJR employing a medial stabilized construct design...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29681492/revision-total-knee-arthroplasty-for-arthrofibrosis
#13
Richard W Rutherford, Jason M Jennings, Daniel L Levy, Thomas J Parisi, J Ryan Martin, Douglas A Dennis
BACKGROUND: Arthrofibrosis after TKA is a significant cause of patient dissatisfaction. There is little evidence regarding revision arthroplasty in this patient population. The purpose of this study is to evaluate outcomes after revision TKA for arthrofibrosis. METHODS: We retrospectively reviewed 46 consecutive revision TKAs for arthrofibrosis between 2007 and 2015 with minimum 2-year follow-up. Range of motion (ROM), complication rates, and Knee Society Scores (KSS) were recorded...
March 23, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29671707/prediction-of-cognitive-performance-and-subjective-sleepiness-using-a-model-of-arousal-dynamics
#14
Svetlana Postnova, Steven W Lockley, Peter A Robinson
A model of arousal dynamics is applied to predict objective performance and subjective sleepiness measures, including lapses and reaction time on a visual Performance Vigilance Test (vPVT), performance on a mathematical addition task (ADD), and the Karolinska Sleepiness Scale (KSS). The arousal dynamics model is comprised of a physiologically based flip-flop switch between the wake- and sleep-active neuronal populations and a dynamic circadian oscillator, thus allowing prediction of sleep propensity. Published group-level experimental constant routine (CR) and forced desynchrony (FD) data are used to calibrate the model to predict performance and sleepiness...
April 2018: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29671128/a-phase-i-study-of-the-pharmacokinetics-and-pharmacodynamics-of-intranasal-doxylamine-in-subjects-with-chronic-intermittent-sleep-impairment
#15
Mark Allison, Cecilia Hale
INTRODUCTION: Doxylamine tablets are approved as an over-the-counter sleep aid. We developed a doxylamine succinate intranasal metered-dose delivery system with the expectation of a more rapid onset of action with reduced side-effect potential compared with the oral tablet. METHODS: This phase I study randomized 24 adults with chronic intermittent sleep impairment to receive either single doses of intranasal doxylamine succinate 3.2, 6.3, or 12.7 mg or doxylamine succinate 25-mg oral tablet...
April 18, 2018: Drugs in R&D
https://www.readbyqxmd.com/read/29664816/evaluating-the-accuracy-and-quality-of-the-information-in-kyphosis-videos-shared-on-youtube
#16
Mehmet Nuri Erdem, Sinan Karaca
STUDY DESIGN: A quality-control YouTube-based study using the recognized quality scoring systems. OBJECTIVE: In this study, our aim was to confirm the accuracy and quality of the information in kyphosis videos shared on YouTube. SUMMARY OF BACKGROUND DATA: The Internet is a widely and increasingly used source for obtaining medical information both by patients and clinicians. YouTube, in particular, manifests itself as a leading source with its ease of access to information and visual advantage for Internet users...
April 16, 2018: Spine
https://www.readbyqxmd.com/read/29656972/clinical-outcomes-of-gap-balancing-vs-measured-resection-in-total-knee-arthroplasty-a-systematic-review-and-meta-analysis-involving-2259-subjects
#17
Shuxiang Li, Xiaomin Luo, Peng Wang, Han Sun, Kun Wang, Xiaoliang Sun
BACKGROUND: The argument on the clinical effects between gap balancing (GB) and measured resection (MR) in total knee arthroplasty remains to be resolved. A systematic review and meta-analysis was performed to investigate which technique in total knee arthroplasty has better clinical effect. METHODS: A total of 20 studies involving 2259 cases were included in the meta-analysis. The primary outcome measure was Knee Society Score (KSS), whereas the secondary outcomes included other function assessment systems (eg, range of motion, Western Ontario and McMaster University Osteoarthritis Index), radiological outcomes (eg, femoral component rotation, total outliers), revision rate, complications (eg, infection, loosening, instability), and surgical time...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29656129/no-difference-in-implant-survivorship-and-clinical-outcomes-between-full-cementless-and-full-cemented-fixation-in-primary-total-knee-arthroplasty-a-systematic-review-and-meta-analysis
#18
REVIEW
Kai Zhou, Haoda Yu, Jinglong Li, Haoyang Wang, Zongke Zhou, Fuxing Pei
BACKGROUND: The debate over the use of cemented or cementless fixation in total knee arthroplasty (TKA) has never stopped since cementless fixation was introduced. We undertook a systematic review and meta-analysis to evaluate the optimal mode of fixation (full-cementless vs. full-cemented) in TKA. METHODS: PubMed, Embase, and the Cochrane Library databases up to July 2017 were searched to identify randomised controlled trials (RCTs) and quasi-RCTs comparing full-cementless TKA and full-cemented TKA...
April 12, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29628683/short-term-outcomes-of-long-duration-versus-short-duration-tourniquet-in-primary-total-knee-arthroplasty-a-randomized-controlled-trial
#19
Raju Vaishya, Amit Kumar Agarwal, Vipul Vijay, Manish Kumar Tiwari
Introduction: A tourniquet is used during the total knee replacement surgery to improve the visibility, to reduce the blood loss and for better cementation. Indirectly it decreases the duration of surgery and enhances the recovery of the patient. Their use however is controversial due to some side effects associated with the use of tourniquet. They may increase the risk of deep vein thrombosis and pulmonary embolism by causing venous stasis, endothelial damage and increased platelet adhesion secondary to distal limb ischemia...
January 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29623574/does-patient-specific-instrumentation-improve-femoral-and-tibial-component-alignment-in-total-knee-arthroplasty-a-prospective-randomized-study
#20
Artur Stolarczyk, Lukasz Nagraba, Tomasz Mitek, Magda Stolarczyk, Jarosław Michał Deszczyński, Maciej Jakucinski
Alignment of the prosthesis is one of the most significant factors that affect the long-term clinical outcome following total knee arthroplasty (TKA). There is conflicting evidence whether patient-specific instrumentation (PSI) for TKA improves the component position compared to standard instrumentation. This study aimed to compare the rotational alignment of the femoral and tibial components in TKA patients when performed with either conventional or PSI. Sixty patients with primary knee osteoarthritis were randomly divided into two groups treated surgically with TKA: one with conventional instrumentation and the other with the Visionaire PSI system (Smith and Nephew, Memphis, TN)...
April 6, 2018: Advances in Experimental Medicine and Biology
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