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https://www.readbyqxmd.com/read/27602132/rapid-bone-repair-in-a-patient-with-lung-cancer-metastases-to-the-spine-using-a-novel-herbal-medicine-a-case-report
#1
Rong Pu, Qianhong Zhao, Zhimei Li, Lingyan Zhang, Xiaolu Luo, Yangji Zeren, Cui Yu, Xianyong Li
The prognosis of lung carcinoma with metastasis to the bone, particularly to the spine, is poor. Chemotherapy and radiotherapy are established treatments for metastatic bone disease, but their effectiveness is unsatisfactory and bone repair following their use is slow and difficult. Medicine prepared from herbal extracts may be an alternative treatment option. The present study discusses the case of a 59-year-old patient diagnosed with squamous cell lung cancer (T2N3M1) in which first-line chemotherapy using docetaxel plus cisplatin failed...
September 2016: Oncology Letters
https://www.readbyqxmd.com/read/27468539/-clinical-value-of-tongguanteng-radix-seu-herba-marsdeniae-tenacissimae-extract-combined-with-chemotherapy-in-the-treatment-of-advanced-non-small-cell-lung-cancer-a-meta-analysis
#2
REVIEW
Haiming Zhang, Junli Zhang, Hao Ding, Rui Chen, Fengxia Liang
OBJECTIVE: To investigate the clinical efficacy and safety of Tongguanteng (Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy in the treatment of advanced non-small cell lung cancer (NCSLC) compared with chemotherapy alone. METHODS: Databases including Chinese National Knowledge Infrastructure, China Biology Medicine Disc, Wanfang, and MEDLINE were searched until April 1, 2014. Two assessors independently reviewed each trial. The primary outcome was the effective rate (ER) of Tongguanteng (Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy...
June 2016: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
https://www.readbyqxmd.com/read/26386954/study-on-the-pharmacokinetic-profiles-of-corynoline-and-its-potential-interaction-in-traditional-chinese-medicine-formula-shuanghua-baihe-tablets-in-rats-by-lc-ms-ms
#3
Ruijuan Liu, Pan Gu, Lei Wang, Minlu Cheng, Yao Wu, Lu Zheng, Yujie Liu, Li Ding
Corynoline, the major isoquinoline alkaloid component derived from Corydalis bungeana Herba, has greatly impressed many scientists due to its various pharmacological effects. However, there is little information on its pharmacokinetics. In this study, a sensitive and rapid liquid chromatography with tandem mass spectrometry method has been developed and validated for the determination of corynoline in rat plasma. The calibration curve showed good linearity within the concentration range of 0.01-20 ng/mL. The method was fully validated and successfully applied in a pharmacokinetic study of corynoline in rats, in which the rats were treated with corynoline, corynoline combined with berberine and the traditional Chinese medicine formula Shuanghua Baihe tablets (SBT, containing corynoline, berberine and other ingredients), respectively...
January 5, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/25790672/-adjunctive-treatment-of-axial-undifferentiated-spondyloarthritis-by-qiangji-recipe-a-clinical-study
#4
RANDOMIZED CONTROLLED TRIAL
Meng-Yin He, Fu-Yuan Fan
OBJECTIVE: To evaluate the clinical efficacy and safety of Qiangji Recipe (QR) in ad- junctive treatment of axial undifferentiated spondyloarthritis (axuSpA) through a four-week open study. METHODS: Fifty-four axuSpA patients of Shen-deficiency Du-channel cold syndrome (SDDCS) in line with inclusive criteria were recruited and assigned to the treatment group and the control group according to random digit table, 27 in each group. Patients in the control group took Celecoxib Capsule (0...
January 2015: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/25722078/hours-in-non-parental-child-care-are-related-to-language-development-in-a-longitudinal-cohort-study
#5
M P C M Luijk, M Linting, J Henrichs, C M Herba, M L Verhage, J J Schenk, L R Arends, H Raat, V W V Jaddoe, A Hofman, F C Verhulst, H Tiemeier, M H van IJzendoorn
BACKGROUND: The effects of child care services on several domains of child development have been extensively investigated, but evidence regarding the effects of child care on language development remains inconclusive. METHODS: Within a large-scale population-based study, we examined the longitudinal associations between non-parental child care and language development from 1 to 6 years (n = 5375). RESULTS: Results showed that more hours in non-parental child care were associated with better language abilities...
November 2015: Child: Care, Health and Development
https://www.readbyqxmd.com/read/25324527/simultaneous-quantification-and-pharmacokinetics-of-alkaloids-in-herba-ephedrae-radix-aconiti-lateralis-extracts
#6
Shuai Song, Qingfa Tang, Huiling Huo, Hancheng Li, Xuefeng Xing, Jiabo Luo
The combination of Herba Ephedrae (Mahuang in Chinese) and Radix Aconiti Lateralis (Fuzi in Chinese) is a classical preparation in traditional Chinese medicine and used for treating colds and rheumatic arthralgia. However, herbal medicines containing ephedrines and Aconitum alkaloids are strictly regulated because of the potential for adverse effects on the cardiovascular system and the central nervous system. We aimed to investigate the pharmacokinetics of 11 alkaloids in the Mahuang-Fuzi combination and single-herb extracts after oral administration in rats...
January 2015: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/24929107/pharmacokinetic-comparisons-of-five-ephedrine-alkaloids-following-oral-administration-of-four-different-mahuang-guizhi-herb-pair-aqueous-extracts-ratios-in-rats
#7
COMPARATIVE STUDY
Ping Wei, Hui-ling Huo, Qing-hai Ma, Han-cheng Li, Xue-feng Xing, Xiao-mei Tan, Jia-bo Luo
ETHNOPHARMACOLOGICAL RELEVANCE: Herba Ephedra (Mahuang in Chinese), is derived from dried Ephedra sinica Stapf stems and has been widely used to treat the common cold, coughs, asthma, and edema for thousands of years. The Mahuang-Guizhi herb-pair is a famous formula composed of Mahuang and Ramulus Cinnamomi (Guizhi in Chinese, the dried twig of Cinnamomum cassia Presl.), used to improve pharmacological effects and reduce toxicity. In order to investigate the influence of Mahuang-Guizhi herb-pair ratios on bioavailability, the plasma pharmacokinetics profiles of five ephedrine alkaloids were compared following oral administration of four different ratios to rats...
August 8, 2014: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/24728546/from-positive-emotionality-to-internalizing-problems-the-role-of-executive-functioning-in-preschoolers
#8
Akhgar Ghassabian, Eszter Székely, Catherine M Herba, Vincent W Jaddoe, Albert Hofman, Albertine J Oldehinkel, Frank C Verhulst, Henning Tiemeier
Temperament and psychopathology are intimately related; however, research on the prospective associations between positive emotionality, defined as a child's positive mood states and high engagement with the environment, and psychopathology is inconclusive. We examined the longitudinal relation between positive emotionality and internalizing problems in young children from the general population. Furthermore, we explored whether executive functioning mediates any observed association. Within a population-based Dutch birth cohort, we observed positive emotionality in 802 children using the laboratory temperament assessment battery at age 3 years...
September 2014: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/24400706/maternal-depressive-symptoms-are-associated-with-low-fearfulness-in-preschoolers
#9
Eszter Székely, Henning Tiemeier, Pauline W Jansen, Vincent W V Jaddoe, Albert Hofman, Frank C Verhulst, Catherine M Herba
The purpose of this study is to examine whether maternal depressive symptoms predict low positive emotionality and high temperamental fearfulness in preschool children. Maternal depressive symptoms were assessed prenatally and at 2, 6, and 36 months postnatally. Positive emotionality and temperamental fearfulness were assessed using laboratory observations in a large cohort of typically developing Dutch preschoolers (N = 799; 404 boys) at age 36 months (M = 37.53, SD = 1.50). Children exposed to elevated levels of maternal depressive symptoms in the first 3 years of life behaved less fearfully at age 3 years in a novel context that primarily elicited a startle response (B = -0...
2014: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/24055915/late-onset-congenital-diaphragmatic-hernia-a-case-report
#10
Marcel Tapia Vega, Regina Herbas Maldonado, Gretty Tapia Vega, Alenka Tapia Vega, Elisafat Arce Liévano, Paulina Moctezuma Velázquez
INTRODUCTION: A Bochdalek hernia is a posterior congenital defect of the diaphragm, usually on the left hemidiafragm, caused by a lack of closure of the pleuroperitoneal canal between the eighth and tenth week of fetal life during the embryonic development. It typically presents in the neonatal period with severe respiratory failure. PRESENTATION OF CASE: In this paper we present a 35 year old man with a 5-year history of episodes of severe dyspnea who arrived to the emergency room, during his medical work-up we incidentally found an intrathoracic gastric bubble, a laparoscopy was performed, founding a necrotic stomach and for defect correction...
2013: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/23983777/can-medical-herbs-stimulate-regeneration-or-neuroprotection-and-treat-neuropathic-pain-in-chemotherapy-induced-peripheral-neuropathy
#11
Sven Schröder, Kathrin Beckmann, Giovanna Franconi, Gesa Meyer-Hamme, Thomas Friedemann, Henry Johannes Greten, Matthias Rostock, Thomas Efferth
Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan), Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto), Huang Qi Wu Wu Tang (Ogikeishigomotsuto), and Shao Yao Gan Cao Tang (Shakuyakukanzoto)...
2013: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/23167730/breastfeeding-and-early-brain-development-the-generation-r-study
#12
Catherine M Herba, Sabine Roza, Paul Govaert, Albert Hofman, Vincent Jaddoe, Frank C Verhulst, Henning Tiemeier
Breastfeeding during infancy is associated with a range of short- and long-term health benefits. We examine whether breastfeeding in the first 2 months of life is associated with structural markers of brain development in infants from the general population. This study was embedded within the Generation R study. Cranial ultrasounds were obtained at approximately 7 weeks post-natal age. The diameter of the gangliothalamic ovoid, corpus callosum length, ventricular volume and head circumference were measured...
July 2013: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/22803386/-regularity-analysis-on-clinical-treatment-in-primary-liver-cancer-by-traditional-chinese-medicine
#13
Xiaoni Liu, Ning Li
OBJECTIVE: To evaluate clinical treatment regularity of traditional Chinese medicine (TCM) on primary liver cancer and provide inspiration for the clinical use. METHOD: Traditional Chinese medicine database on primary liver cancer was established to analysis the classification, frequency, dosage of TCM in clinical treatment. RESULT: Tonic medicine is the most common medication, herbs for heat-clearing, promoting blood circulation for removing blood stasis, eliminating dampness and diuresis and regulating flow of Qi are more common medication, herbs for relieving exterior disorder and digesting are common medication; the first frequency of single herb is Atractglodis Macrocephalae Rhizoma, Poria, Codonopsis Radix...
May 2012: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/19381859/safety-of-an-injection-with-a-mixture-of-extracts-from-herba-artemisiae-annuae-fructus-gardeniae-and-flos-lonicerae
#14
MULTICENTER STUDY
Hou Ming Xu, Yue Wang, Nai Feng Liu
OBJECTIVE: This study aimed to evaluate the safety for an injection with a mixture of extracts from Herba Artemisiae annuae, Fructus Gardeniae and Flos Lonicerae and to determine the risk factors that may affect its adverse drug reactions. METHODS: A drug-oriented prospective observational study was performed. Physicians filled in clinical observation forms with detailed information of the patients including general information, drug information, therapeutic effects and adverse drug events...
August 2009: Pharmacy World & Science: PWS
https://www.readbyqxmd.com/read/19371465/elimination-of-ephedrines-in-urine-following-administration-of-a-sho-seiryu-to-preparation
#15
Kuei Hui Chan, Mei-Chich Hsu, Fu-An Chen, Ku-Fu Hsu
Sho-seiryu-to is one of the most common Traditional Chinese Medicine preparations for the attenuation of colds. Ephedrae Herba is one of the prescriptions of Sho-seiryu-to. The major ingredients of Ephedrae Herba, ephedrines, are banned substances on the World Anti-Doping Agency (WADA) list. The purpose of this study was to investigate the elimination of urinary ephedrines after administering Sho-seiryu-to preparation and to determine the possibility of positive ephedrines test results in urine. Six healthy volunteers took a single 2...
April 2009: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/19021932/urinary-elimination-of-ephedrines-following-administration-of-the-traditional-chinese-medicine-preparation-kakkon-to
#16
Kuei Hui Chan, Ryh-Nan Pan, Mei-Chich Hsu, Ku-Fu Hsu
Kakkon-to is one of the most common Traditional Chinese Medicine preparations for the attenuation of colds. Ephedrae Herba is one of the prescriptions of Kakkon-to. The major ingredients of Ephedrae Herba, ephedrines, are banned substances on the World Anti-Doping Agency (WADA) list. The purpose of this study was to investigate the elimination of urinary ephedrines after administering Kakkon-to and to determine the possibility of urinary positive ephedrine test results. Six healthy volunteers took one single dose of 2...
November 2008: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/19004205/the-effect-enhancing-and-toxicity-reducing-action-of-the-extract-of-herba-scutellariae-barbatae-for-chemotherapy-in-hepatoma-h22-tumor-bearing-mice
#17
Zhijun Dai, Xiaoxu Liu, Zongzheng Ji, Lei Liu, Huafeng Kang, Xijing Wang, Yan Diao
OBJECTIVE: To investigate the effect-enchancing and toxicity-reducing action of the extract of Ban Zhi Lian (Herba Scutellariae Barbatae, EHSB) for chemotherapy in hepatoma H22 tumor-bearing mice. METHODS: The tumor-bearing mice were divided into 6 groups randomly: a model group, a high dose EHSB group, a low dose EHSB group, a 5-fluorouracil (5-FU) group, a 5-FU+high dose EHSB group and a 5-FU+low dose EHSB group, and with a normal group set as the controls. All the groups were treated for 10 days...
September 2008: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
https://www.readbyqxmd.com/read/18923070/amygdala-hypoactivity-to-fearful-faces-in-boys-with-conduct-problems-and-callous-unemotional-traits
#18
Alice P Jones, Kristin R Laurens, Catherine M Herba, Gareth J Barker, Essi Viding
OBJECTIVE: Although early-onset conduct problems predict both psychiatric and health problems in adult life, little research has been done to index neural correlates of conduct problems. Emerging research suggests that a subgroup of children with conduct problems and elevated levels of callous-unemotional traits may be genetically vulnerable to manifesting disturbances in neural reactivity to emotional stimuli indexing distress. Using functional MRI, the authors evaluated differences in neural response to emotional stimuli between boys with conduct problems and elevated levels of callous-unemotional traits and comparison boys...
January 2009: American Journal of Psychiatry
https://www.readbyqxmd.com/read/16052824/-quality-of-life-in-patients-suffering-from-choroideremia
#19
Dorota Pojda-Wilczek, Ewa Herba, Stefan M Pojda, Katarzyna Makowiecka-Obidzińska
PURPOSE: To direct attention on every-day problems in choroideremia, which are not a barrier in patients occupation. MATERIAL AND METHODS: Two cases of patients with choroideremia which was diagnosed when they were 30 and 54 are described. In spite of widespread visual field changes patients with good visual acuity did not have to change their lifestyles or their jobs (miner and mechanic). Visual acuity, visual field, mesoptometry, adaptometry, electroretinography, electrooculography were done...
2005: Klinika Oczna
https://www.readbyqxmd.com/read/15637565/the-chinese-herbal-medicine-formula-fahf-2-completely-blocks-anaphylactic-reactions-in-a-murine-model-of-peanut-allergy
#20
Kamal D Srivastava, Jacob D Kattan, Zhong Mei Zou, Jing Hua Li, Libang Zhang, Sylvan Wallenstein, Joseph Goldfarb, Hugh A Sampson, Xiu-Min Li
BACKGROUND: Peanut allergy is potentially life threatening. There is no curative therapy for this disorder. We previously found that an herbal formula, food allergy herbal formula (FAHF)-1, blocked peanut-induced anaphylaxis in a murine model when challenged immediately posttherapy. OBJECTIVE: To test whether FAHF-2, an improved herbal formula, from which 2 herbs, Zhi Fu Zi (Radix Lateralis Aconiti Carmichaeli Praeparata) and Xi Xin (Herba Asari), were eliminated, is equally effective to FAHF-1, and if so, whether protection persists after therapy is discontinued...
January 2005: Journal of Allergy and Clinical Immunology
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