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https://www.readbyqxmd.com/read/29240930/britain-breathing-using-the-experience-sampling-method-to-collect-the-seasonal-allergy-symptoms-of-a-country
#1
Markel Vigo, Lamiece Hassan, William Vance, Caroline Jay, Andrew Brass, Sheena Cruickshank
Objective: Allergies are increasing, but the reasons for this are unclear. Although environmental factors are thought to be important, there is a lack of data on how they contribute to symptom development. To understand this relationship better, we need accurate data about both symptoms and environmental factors. Our objective here is to ascertain whether experience sampling is a reliable approach for collecting allergy symptom data in the general population, allowing us to map symptoms and understand etiology...
December 12, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29238261/physical-physiological-and-perceptual-match-demands-of-amateur-mixed-gender-touch-players
#2
Will Vickery, Alice Harkness
The purpose of this study was to provide a position specific (middle, link [male], link [female], wing) analysis of mixed gender touch on the physical physiological and perceptual demands of amateur players during match-play across a season. Distance and speed measures were obtained through the use of 10-Hz global positioning system devices, whilst telemetric heart rate devices were used determine a range of physiological measures. Players also provided a rating of perceived exertion following each match. The greatest physical demand was associated with the middle playing position by comparison to all others (Distance travelled ≥5...
December 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29236624/a-socio-ecological-examination-of-treatment-access-uptake-and-adherence-issues-encountered-by-hiv-positive-women-in-rural-north-central-nigeria
#3
Llewellyn J Cornelius, Salome C Erekaha, Joshua N Okundaye, Nadia A Sam-Agudu
BACKGROUND: In spite of the global decline in HIV infections, sub-Saharan Africa still accounts for a non-proportional majority of global new infections. While many studies have documented the importance of facilitating access to anti-retroviral therapy (ART) as a means of reducing infections, the relationship between interpersonal, community, healthcare facility, and policy-level factors and treatment adherence in Africa have not been well-described. The authors examined these factors in the context of prevention of mother-to-child transmission (PMTCT) of HIV in rural north-central Nigeria, where HIV burden is high and service coverage is low...
December 13, 2017: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/29235710/localized-high-abundance-of-marine-group-ii-archaea-in-the-subtropical-pearl-river-estuary-implications-for-their-niche-adaptation
#4
Wei Xie, Haiwei Luo, Senthil K Murugapiran, Jeremy A Dodsworth, Songze Chen, Ying Sun, Brian P Hedlund, Peng Wang, Huaying Fang, Minghua Deng, Chuanlun Zhang
Marine group II archaea are widely distributed in global oceans and dominate the total archaeal community within the upper euphotic zone of temperate waters. However, factors controlling the distribution of MGII are poorly delineated and the physiology and ecological functions of these still-uncultured organisms remain elusive. In this study, we investigated the planktonic MGII associated with particles and in free-living forms in the Pearl River Estuary (PRE) over a 10-month period. We detected high abundance of particle-associated MGII in PRE (up to ∼108 16S rRNA gene copies/L), which was around 10-fold higher than the free-living MGII in the same region, and an order of magnitude higher than previously reported in other marine environments...
December 13, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29235543/purification-of-replicating-pancreatic-%C3%AE-cells-for-gene-expression-studies
#5
Reyes Carballar, Maria de Lluc Canyelles, Claudia Fernández, Yasmina Martí, Sarah Bonnin, Esther Castaño, Eduard Montanya, Noèlia Téllez
β-cell proliferation is a rare event in adult pancreatic islets. To study the replication-related β-cell biology we designed a replicating β-cells sorting system for gene expression experiments. Replicating β-cells were identified by EdU incorporation and purified by flow cytometry. For β-cell separation islet cells were sorted by size, granularity and Newport Green fluorescence emission that was combined with emitted fluorescence for EdU-labelled replicating cells sorting. The purity of the resulting sorted populations was evaluated by insulin staining and EdU for β-cell identification and for replicating cells, respectively...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29234302/home-based-virtual-reality-augmented-training-improves-lower-limb-muscle-strength-balance-and-functional-mobility-following-chronic-incomplete-spinal-cord-injury
#6
Michael Villiger, Jasmin Liviero, Lea Awai, Rahel Stoop, Pawel Pyk, Ron Clijsen, Armin Curt, Kynan Eng, Marc Bolliger
Key factors positively influencing rehabilitation and functional recovery after spinal cord injury (SCI) include training variety, intensive movement repetition, and motivating training tasks. Systems supporting these aspects may provide profound gains in rehabilitation, independent of the subject's treatment location. In the present study, we test the hypotheses that virtual reality (VR)-augmented training at home (i.e., unsupervised) is feasible with subjects with an incomplete SCI (iSCI) and that it improves motor functions such as lower limb muscle strength, balance, and functional mobility...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29234080/genomic-diversity-and-macroecology-of-the-crop-wild-relatives-of-domesticated-pea
#7
Petr Smýkal, Iveta Hradilová, Oldřich Trněný, Jan Brus, Abhishek Rathore, Michael Bariotakis, Roma Rani Das, Debjyoti Bhattacharyya, Christopher Richards, Clarice J Coyne, Stergios Pirintsos
There is growing interest in the conservation and utilization of crop wild relatives (CWR) in international food security policy and research. Legumes play an important role in human health, sustainable food production, global food security, and the resilience of current agricultural systems. Pea belongs to the ancient set of cultivated plants of the Near East domestication center and remains an important crop today. Based on genome-wide analysis, P. fulvum was identified as a well-supported species, while the diversity of wild P...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233465/physical-demands-and-technical-performance-in-australian-football-league-women-s-aflw-competition-match-play
#8
Anthea C Clarke, Samuel Ryan, Georgia Couvalias, Ben J Dascombe, Aaron J Coutts, Thomas Kempton
OBJECTIVES: To compare positional differences in the physical and technical demands of Australian Football League Women's (AFLW) match-play. A secondary aim was to examine the time course changes in activity profiles during AFLW match-play. DESIGN: Longitudinal observational study. METHODS: Global positioning system data were collected from 26 players (6 positional groups) from the same club during seven AFLW matches. Absolute and relative physical performance data were categorised into total distance, high-speed running (>14...
December 5, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29233121/do-retreatment-tuberculosis-patients-need-special-treatment-response-follow-up-beyond-the-standard-regimen-finding-of-five-year-retrospective-study-in-pastoralist-setting
#9
Fentabil Getnet, Henok Sileshi, Wubareg Seifu, Selam Yirga, Abere Shiferaw Alemu
BACKGROUND: Treatment outcomes serve as proxy measures of the quality of tuberculosis treatment provided by the health care system, and it is essential to evaluate the effectiveness of Directly Observed Therapy-Short course program in controlling the disease, and reducing treatment failure, default and death. Hence, we evaluated tuberculosis treatment success rate, its trends and predictors of unsuccessful treatment outcome in Ethiopian Somali region where 85% of its population is pastoralist...
December 12, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29227257/world-and-national-experience-in-organization-of-prevention-of-cardiovascular-diseases
#10
А Biduchak, Zh Chornenka
The aim of the study was to examine the global, European and national experience in the implementation of preventive programs and to reveal their value in health, economy and social health development. The conducted research has found that the implementation of the national program, the correct methodological approach of the physician to evaluate risk factors, and implementing preventive measures of diseases of the circulatory system bring positive results (reduction of prevalence and incidence of cerebral stroke by 13,7% and 1,4%, respectively)...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29227216/front-of-package-nutrition-references-are-positively-associated-with-food-processing
#11
Anthea Christoforou, Naomi Dachner, Rena Mendelson, Valerie Tarasuk
OBJECTIVE: Foods characterized by a high degree of processing are pervasive in the global food supply and concerns have been raised about their contribution to the escalating burden of diet-related disease. It has been suggested that the dominance of these products relates in part to their aggressive on-package marketing. The purpose of the present study was to assess the relationship between the extent and nature of front-of-package (FOP) nutrition references on products sold in Canadian supermarkets and the level of food processing...
January 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29222091/waste-management-informal-recycling-environmental-pollution-and-public-health
#12
Hong Yang, Mingguo Ma, Julian R Thompson, Roger J Flower
With rapid population growth, especially in low-income and middle-income countries, the generation of waste is increasing at an unprecedented rate. For example, annual global waste arising from waste electrical and electronic equipment alone will have increased from 33.8 to 49.8 million tonnes between 2010 and 2018. Despite incineration and other waste treatment techniques, landfill still dominates waste disposal in low-income and middle-income countries. There is usually insufficient funding for adequate waste management in these countries and uptake of more advanced waste treatment technologies is poor...
December 8, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29219097/analysis-of-the-impact-of-healthcare-support-initiatives-for-physically-disabled-people-on-their-access-to-care-in-the-city-of-saint-louis-senegal
#13
Diarra Bousso Senghor, Oumar Diop, Issa Sombié
BACKGROUND: People with disabilities represent approximately 6% of the Senegalese population. They face significant barriers to accessing health care. Although several initiatives have been implemented to improve access to health care for this vulnerable population, few studies have examined the effects of these initiatives. We conducted a mixed methods study in three neighborhoods in Saint-Louis City (Senegal) to assess the impact of health systems and social assistance programs aimed at improving access to health care for people with disabilities...
December 4, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29219084/an-improved-bayesian-network-method-for-reconstructing-gene-regulatory-network-based-on-candidate-auto-selection
#14
Linlin Xing, Maozu Guo, Xiaoyan Liu, Chunyu Wang, Lei Wang, Yin Zhang
BACKGROUND: The reconstruction of gene regulatory network (GRN) from gene expression data can discover regulatory relationships among genes and gain deep insights into the complicated regulation mechanism of life. However, it is still a great challenge in systems biology and bioinformatics. During the past years, numerous computational approaches have been developed for this goal, and Bayesian network (BN) methods draw most of attention among these methods because of its inherent probability characteristics...
November 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29218318/patient-comfort-scores-do-not-affect-endoscopist-behavior-during-colonoscopy-while-trainee-involvement-has-negative-effects-on-patient-comfort
#15
Brian P H Chan, Amanda Hussey, Natalie Rubinger, Lawrence C Hookey
Introduction : Patient comfort is an important part of endoscopy and reflects procedure quality and endoscopist technique. Using the validated, Nurse Assisted Patient Comfort Score (NAPCOMS), this study aimed to determine whether the introduction of NAPCOMS would affect sedation use by endoscopists. Patients and methods : The study was conducted over 3 phases. Phase One and Two consisted of 8 weeks of endoscopist blinded and aware data collection, respectively...
December 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29215301/the-positioning-of-aboriginal-students-and-their-languages-within-australia-s-education-system-a-human-rights-perspective
#16
Leonard A Freeman, Bea Staley
This paper is a critical review of past and present languages policies in Australian schooling. We highlight the One Literacy movement that contravenes the human rights of Australia's Aboriginal students. This in turn impacts students' right to freedom of opinion and expression as stated in Article 19 of the Universal Declaration of Human Rights. The One Literacy movement operates by equating Standard Australian English literacy acquisition with Australia's global competitiveness and economic success. There is only one pathway through the Australian English curriculum with common assessments and standards...
December 7, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29214429/reduction-and-stability-analysis-of-a-transcription-translation-model-of-rna-polymerase
#17
Ismail Belgacem, Stefano Casagranda, Edith Grac, Delphine Ropers, Jean-Luc Gouzé
The aim of this paper is to analyze the dynamical behavior of biological models of gene transcription and translation. We focus on a particular positive feedback loop governing the synthesis of RNA polymerase, needed for transcribing its own gene. We write a high-dimension model based on mass action laws and reduce it to a two-variable model (RNA polymerase and its mRNA) by means of monotone system theory and timescale arguments. We show that the reduced model has either a single globally stable trivial equilibrium in (0, 0), or an unstable zero equilibrium and a globally stable positive one...
December 6, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29211200/air-pollution-and-hospitalizations-in-the-largest-brazilian-metropolis
#18
Nelson Gouveia, Flavia Prado Corrallo, Antônio Carlos Ponce de Leon, Washington Junger, Clarice Umbelino de Freitas
OBJECTIVE: To evaluate the impact of air pollution on hospitalizations for respiratory and cardiovascular diseases in the largest Brazilian metropolis. METHODS: This study was carried out at the Metropolitan Region of São Paulo, Brazil. Environmental data were obtained from the network of monitoring stations of nine municipalities. Air pollution exposure was measured by daily means of PM10 (particles with a nominal mean aerodynamic diameter ≤ 10 μm) per municipality, while daily counts of hospitalizations for respiratory and cardiovascular diseases within the Brazilian Unified Health System were the outcome...
December 4, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29210954/examining-the-influence-of-exercise-intensity-and-hydration-on-gastrointestinal-temperature-in-collegiate-football-players
#19
Julie K DeMartini-Nolan, Jessica L Martschinske, Douglas J Casa, Rebecca M Lopez, Rebecca L Stearns, Matthew S Ganio, Eric Coris
Debate exists regarding the influence of intensity and hydration on body temperature during American football. The purpose of this study was to observe body core temperature responses with changes in intensity and hydration. Twenty-nine male football players (age=21±1y, height=187±9 cm, mass=110.1±23.5 kg, body mass index (BMI)=31.3±5.0, and body surface area (BSA)=2.34±0.27m2) participated in eight days of practice in a warm environment (WBGT:29.6±1.6°C). Participants were identified as Starters (S;n=12) or Non-Starters (NS;n=17) and Linemen (L;n=14) or Non-Linemen (NL;n=15)...
November 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29209525/final-results-of-the-large-scale-multinational-trial-profile-1005-efficacy-and-safety-of-crizotinib-in-previously-treated-patients-with-advanced-metastatic-alk-positive-non-small-cell-lung-cancer
#20
Fiona Blackhall, D Ross Camidge, Alice T Shaw, Jean-Charles Soria, Benjamin J Solomon, Tony Mok, Vera Hirsh, Pasi A Jänne, Yuankai Shi, Pan-Chyr Yang, Tommaso De Pas, Toyoaki Hida, Javier De Castro Carpeño, Silvana Lanzalone, Anna Polli, Shrividya Iyer, Arlene Reisman, Keith D Wilner, Dong-Wan Kim
Purpose: Crizotinib is a potent, orally administered tyrosine kinase inhibitor approved for the treatment of anaplastic lymphoma kinase (ALK)-positive advanced non-small-cell lung cancer (NSCLC). We report final results from PROFILE 1005, the largest clinical trial to date for an ALK inhibitor in ALK-positive NSCLC. Patients and methods: PROFILE 1005 (NCT00932451) was a multicenter, single-arm phase 2 trial of the efficacy, safety and tolerability of crizotinib (250 mg twice daily; 3 week continuous treatment cycles) in patients with ALK-positive NSCLC after failure of ≥1 lines of systemic treatment for locally advanced/metastatic disease...
2017: ESMO Open
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